|
Name |
Accession |
Description |
Interval |
E-value |
| secA2 |
TIGR03714 |
accessory Sec system translocase SecA2; Members of this protein family are homologous to SecA ... |
9-771 |
0e+00 |
|
accessory Sec system translocase SecA2; Members of this protein family are homologous to SecA and part of the accessory Sec system. This system, including both five core proteins for export and a variable number of proteins for glycosylation, operates in certain Gram-positive pathogens for the maturation and delivery of serine-rich glycoproteins such as the cell surface glycoprotein GspB in Streptococcus gordonii. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 163426 [Multi-domain] Cd Length: 762 Bit Score: 1228.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 9 INNMRLRRLQKKLDQINRLGETFVTYSNQALKAMTKEFKKRLNKpRESLDTILPEAYAVVREASRRVLGMYPKDVQVLGA 88
Cdd:TIGR03714 1 INNLRLKKLRKILNKINALKGKMATLSDEELQAKTAEFKNRLVE-GESLDDILPEAYAVVREADKRVLGMFPYDVQVLGA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 89 IVLHEGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTTSLGFVDIPDYEYQKNEK 168
Cdd:TIGR03714 80 IVLHQGNIAEMKTGEGKTLTATMPLYLNALTGKGAMLVTTNDYLAKRDAEEMGPVYEWLGLTVSLGVVDDPDEEYDANEK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 169 AMLYKHDIVYTTNGRLGFDYLIDNLADSIEGKFLPKLNYGIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETL 248
Cdd:TIGR03714 160 RKIYNSDIVYTTNSALGFDYLIDNLASNKEGKFLRPFNYVIVDEVDSVLLDSAQTPLVISGAPRVQSNLYHIADTFVRTL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 249 EKDIHFKVKKAKKEIWLTEAGIEAANQYFNVSDIYDEPYFDLARNINLALRAHHLFESNLDYFVYNGEVVLIDRITGRML 328
Cdd:TIGR03714 240 KEDVDYIFKKDKKEVWLTDKGIEKAEQYFKIDNLYSEEYFELVRHINLALRAHYLFKRNKDYVVTNGEVVLLDRITGRLL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 329 PGTKLQSGLHQAIEAKEQIDISLDMSVMATITFQNLFKQFEDFAGMTGTGKMDEPEFFNLYSKIVIQIPTDRPVQRIDYD 408
Cdd:TIGR03714 320 EGTKLQSGIHQAIEAKEHVELSKETRAMASITYQNLFKMFNKLSGMTGTGKVAEKEFIETYSLSVVKIPTNKPIIRIDYP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 409 DRVFKTEADKNQAIIDKVQELHAQKRPILLITRTAEAAEKFSSTLFKMDIPNNLLIAQNVAKEAQMIAEAGQLAAVTVAT 488
Cdd:TIGR03714 400 DKIYATLPEKLMATLEDVKEYHETGQPVLLITGSVEMSEIYSELLLREGIPHNLLNAQNAAKEAQIIAEAGQKGAVTVAT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 489 SMAGRGTDIKLHPEVQDLGGLAVIINEHMENSHVDRQLRGRSGRQGDPGMSQIYISLEDYLVKRWGDDKLTENERLTAMD 568
Cdd:TIGR03714 480 SMAGRGTDIKLGKGVAELGGLAVIGTERMENSRVDLQLRGRSGRQGDPGSSQFFVSLEDDLIKRWSPSWLKKYYKKYSVK 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 569 ADRLESSGVFKRRVKHIVKKAQRLSEEQGMNAREMANDYEKSISLQRELIYDERDRVLNLEHIDEIEFDTLAKEVFRRDY 648
Cdd:TIGR03714 560 DSKLKPSALFKRRFRKIVEKAQRASEDKGESAREQTNEFEESLSIQRENIYAERNRLIEGSDFLDDDVDQIIDDVFNMYA 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 649 IQAEPLTPRTLTEYIYRNISFQFDQDLSTLDISDHHAVIQFLLDLFKSQLETQRQTINDPYFYQRFLQKTILKSIDTTWI 728
Cdd:TIGR03714 640 EEQDLSNKSLLKRFILENLSYQFKNDPDEFDLKNKEAIKDFLKEIADKELSEKKKVLNNDYLFNDFERLSILKAIDENWI 719
|
730 740 750 760
....*....|....*....|....*....|....*....|...
gi 973245241 729 DQVDHLQQLKASVRNRQNGQRNAIFEYHKVALESYEVMCNKIK 771
Cdd:TIGR03714 720 EQVDYLQQLKTVVTNRQNGQRNPIFEYHKEALESYEYMKKEIK 762
|
|
| PRK09200 |
PRK09200 |
preprotein translocase subunit SecA; Reviewed |
1-796 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 236408 [Multi-domain] Cd Length: 790 Bit Score: 1187.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 1 MKQQINTTINNMRLRRLQKKLDQINRLGETFVTYSNQALKAMTKEFKKRLNKpRESLDTILPEAYAVVREASRRVLGMYP 80
Cdd:PRK09200 1 MKKKLLGDIDKRRLKKYRKIVKQINKLEGKMSSLSDEELRQKTIEFKERLAS-GKTLDDILPEAFAVVREAAKRVLGMRP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 81 KDVQVLGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTTSLGFVDIPD 160
Cdd:PRK09200 80 YDVQLIGALVLHEGNIAEMQTGEGKTLTATMPLYLNALEGKGVHLITVNDYLAKRDAEEMGQVYEFLGLTVGLNFSDIDD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 161 yeyqKNEKAMLYKHDIVYTTNGRLGFDYLIDNLADSIEGKFLPKLNYGIIDEVDSIILDAAQTPLVISGAPRVQSNLFHI 240
Cdd:PRK09200 160 ----ASEKKAIYEADIIYTTNSELGFDYLRDNLADSKEDKVQRPLNYAIIDEIDSILLDEAQTPLIISGKPRVQSNLYHI 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 241 VKTFVETLEKDIHFKVKKAKKEIWLTEAGIEAANQYFNVSDIYDEPYFDLARNINLALRAHHLFESNLDYFVYNGEVVLI 320
Cdd:PRK09200 236 AAKFVKTLEEDVDYEFDEEKKEVWLTDQGIEKAESYFGIDNLYSLEHQVLYRHIILALRAHVLFKRDVDYIVYDGEIVLV 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 321 DRITGRMLPGTKLQSGLHQAIEAKEQIDISLDMSVMATITFQNLFKQFEDFAGMTGTGKMDEPEFFNLYSKIVIQIPTDR 400
Cdd:PRK09200 316 DRFTGRVLPGRKLQDGLHQAIEAKEGVEITEENRTMASITIQNLFRMFPKLSGMTGTAKTEEKEFFEVYNMEVVQIPTNR 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 401 PVQRIDYDDRVFKTEADKNQAIIDKVQELHAQKRPILLITRTAEAAEKFSSTLFKMDIPNNLLIAQNVAKEAQMIAEAGQ 480
Cdd:PRK09200 396 PIIRIDYPDKVFVTLDEKYKAVIEEVKERHETGRPVLIGTGSIEQSETFSKLLDEAGIPHNLLNAKNAAKEAQIIAEAGQ 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 481 LAAVTVATSMAGRGTDIKLHPEVQDLGGLAVIINEHMENSHVDRQLRGRSGRQGDPGMSQIYISLEDYLVKRWGDDKLTE 560
Cdd:PRK09200 476 KGAVTVATNMAGRGTDIKLGEGVHELGGLAVIGTERMESRRVDLQLRGRSGRQGDPGSSQFFISLEDDLLKRFAPEELEK 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 561 NERLTAMDADRLESSgVFKRRVKHIVKKAQRLSEEQGMNAREMANDYEKSISLQRELIYDERDRVLNLEHIDEIEFDTLA 640
Cdd:PRK09200 556 LKKKLKTDAQRLTGL-LFNRKVHKIVVKAQRISEGAGYSAREYALELDDVINIQRDVVYKERNRLLEEDDRDLIDIVILM 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 641 KEVFRRDYIQAEPLTPRTLTEYIYRNISFQFDQDLSTLDISDHHAVIQFLLDLFKSQLETQRQTINDPYFYQRFLQKTIL 720
Cdd:PRK09200 635 IDVYLEAVAEEYLLEKSLLEEWIYENLSFQLNEILSNTNFPDKKEVVQFLLEEAEKQLKEKRNKLPSATLYNQFLRKVAL 714
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 973245241 721 KSIDTTWIDQVDHLQQLKASVRNRQNGQRNAIFEYHKVALESYEVMCNKIKGNIIRNLSQSMATFDKDGDLVIHFP 796
Cdd:PRK09200 715 KAIDQNWVEQVDALQQLKEGIGLRQYGQRNPIREYQKEALESFEYMYENIKKDMVRNLLLSLLVFDKEGEIVIHFP 790
|
|
| SecA |
COG0653 |
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, ... |
10-779 |
0e+00 |
|
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440418 [Multi-domain] Cd Length: 876 Bit Score: 695.62 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 10 NNMRLRRLQKKLDQINRLGETFVTYSNQALKAMTKEFKKRLNKpRESLDTILPEAYAVVREASRRVLGMYPKDVQVLGAI 89
Cdd:COG0653 13 NDRELKRLRKIVDKINALEPEMEALSDEELRAKTDEFKERLAN-GETLDDLLPEAFAVVREASKRVLGMRHFDVQLIGGI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 90 VLHEGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTTSLGFVDIPDYEYQKNeka 169
Cdd:COG0653 92 VLHQGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGRLYRFLGLSVGVIVHGMDPEERRAA--- 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 170 mlYKHDIVYTTNGRLGFDYLIDNLADSIEGKFLPKLNYGIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETLE 249
Cdd:COG0653 169 --YAADITYGTNNEFGFDYLRDNMVFSLEDMVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDSTDLYYRINKLVPRLK 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 250 KDIHFKVKKAKKEIWLTEAGIEAANQYFNVSDIYDEPYFDLARNINLALRAHHLFESNLDYFVYNGEVVLIDRITGRMLP 329
Cdd:COG0653 247 RDGDYTVDEKARTVTLTEEGIEKVEKLLGIDNLYDPENIELVHHLNQALRAHALFKRDVDYIVKDGEVVIVDEFTGRLMP 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 330 GTKLQSGLHQAIEAKEQIDISLDMSVMATITFQNLFKQFEDFAGMTGTGKMDEPEFFNLYSKIVIQIPTDRPVQRIDYDD 409
Cdd:COG0653 327 GRRYSDGLHQAIEAKEGVKIQNENQTLASITFQNYFRMYEKLAGMTGTADTEAEEFREIYGLDVVVIPTNRPMIRKDEPD 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 410 RVFKTEADKNQAIIDKVQELHAQKRPILLITRTAEAAEKFSSTLFKMDIPNNLLIAQNVAKEAQMIAEAGQLAAVTVATS 489
Cdd:COG0653 407 LVYKTEEEKFNAVVEDIKERHEKGQPVLVGTTSIEKSELLSKLLKKEGIPHNVLNAKQHEREAEIVAQAGRPGAVTIATN 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 490 MAGRGTDIKL---------------------------------HPEVQDLGGLAVIINEHMENSHVDRQLRGRSGRQGDP 536
Cdd:COG0653 487 MAGRGTDIVLggnpeflaaaeladrgleweeaiakikaewqaeHEEVLEAGGLHVIGTERHESRRIDNQLRGRSGRQGDP 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 537 GMSQIYISLEDYLVKRWGDDKLtEN--ERLtAMDAD-RLESSGVFKRrvkhiVKKAQRLSEeqGMNArEM---------- 603
Cdd:COG0653 567 GSSRFYLSLEDDLMRIFGSDRI-KGmmDKL-GMEEGePIEHKMVSKA-----IENAQKKVE--GRNF-DIrknlleyddv 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 604 ANDyeksislQRELIYDERDRVLNLEHIDEIEFDtlakevFRRDYIQA--EPLTPR----------TLTEYIYRNISFQF 671
Cdd:COG0653 637 MND-------QRKVIYEQRREILEGEDLSETILD------MREDVIEDlvDEYIPEgsypeqwdleGLEEALKELFGLDL 703
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 672 D-QDLSTLDISDHHAVIQFLLDLFKSQLETQRQTINDPYFyqRFLQKTI-LKSIDTTWIDQVDHLQQLKASVRNRQNGQR 749
Cdd:COG0653 704 PiEEWLDEEGLDEEELRERLLEAADEAYEEKEEELGPEVM--RELERVVlLQVLDRKWREHLDAMDHLRQGIGLRGYAQK 781
|
810 820 830
....*....|....*....|....*....|
gi 973245241 750 NAIFEYHKVALESYEVMCNKIKGNIIRNLS 779
Cdd:COG0653 782 DPLVEYKREAFELFEEMLDSIKEEVVRYLF 811
|
|
| SecA_DEAD |
smart00957 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
8-386 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the.
Pssm-ID: 214937 [Multi-domain] Cd Length: 380 Bit Score: 558.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 8 TINNMRLRRLQKKLDQINRLGETFVTYSNQALKAMTKEFKKRLNKpRESLDTILPEAYAVVREASRRVLGMYPKDVQVLG 87
Cdd:smart00957 7 SKNDRELKRLRKIVDQINALEPEMEALSDEELRAKTAEFKERLAE-GESLDDLLPEAFAVVREAAKRVLGMRHFDVQLIG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 88 AIVLHEGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTTSLGFVDIPDyeyqkNE 167
Cdd:smart00957 86 GIVLHEGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLTVGVIVSGMSP-----EE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 168 KAMLYKHDIVYTTNGRLGFDYLIDNLADSIEGKFLPKLNYGIIDEVDSIILDAAQTPLVISG-APRVQSNLFHIVKTFVE 246
Cdd:smart00957 161 RRAAYAADITYGTNNEFGFDYLRDNMAFSKEDKVQRGLNYAIVDEVDSILIDEARTPLIISGpAEDESSDLYHRADKFVP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 247 TLEKDIHFKVKKAKKEIWLTEAGIEAANQYFNVSDIYDEPYFDLARNINLALRAHHLFESNLDYFVYNGEVVLIDRITGR 326
Cdd:smart00957 241 RLKEDEDYTVDEKSRTVELTEEGIEKAEKLLGIDNLYDPENIELLHHVNQALRAHYLFKRDVDYIVRDGEVVIVDEFTGR 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 327 MLPGTKLQSGLHQAIEAKEQIDISLDMSVMATITFQNLFKQFEDFAGMTGTGKMDEPEFF 386
Cdd:smart00957 321 VMEGRRYSDGLHQAIEAKEGVEIQEENQTLATITFQNYFRMYKKLSGMTGTAKTEAEEFR 380
|
|
| SecA_DEAD |
pfam07517 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
8-385 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the pfam00270.
Pssm-ID: 462190 [Multi-domain] Cd Length: 379 Bit Score: 535.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 8 TINNMRLRRLQKKLDQINRLGETFVTYSNQALKAMTKEFKKRLnKPRESLDTILPEAYAVVREASRRVLGMYPKDVQVLG 87
Cdd:pfam07517 7 SPNERDLKRLRKIVDQINALEEELKALSDEELRAKTDELRERL-REGESLDDILPEAFALVREAAKRVLGMRHYDVQLIG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 88 AIVLHEGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTTSLGFVDIPDYEYQKNe 167
Cdd:pfam07517 86 GLVLHEGKIAEMKTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLTVGVITSDMDPEERRAA- 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 168 kamlYKHDIVYTTNGRLGFDYLIDNLADSIEGKFLPKLNYGIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVET 247
Cdd:pfam07517 165 ----YNADITYGTNNELGFDYLRDNMATSKEDKVQRGLNFAIVDEVDSILIDEARTPLIISGPSEDDSELYREADRLVKS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 248 LEKDIHFKVKKAKKEIWLTEAGIEAANQYFNVSDIYDEPYFDLARNINLALRAHHLFESNLDYFVYNGEVVLIDRITGRM 327
Cdd:pfam07517 241 LEEDGDYEIDEKSKNVELTEKGIEKIEKLLGIDNLYDPENVELLHHINQALKAHHLFKRDVDYIVRDGEVVIVDEFTGRV 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 973245241 328 LPGTKLQSGLHQAIEAKEQIDISLDMSVMATITFQNLFKQFEDFAGMTGTGKMDEPEF 385
Cdd:pfam07517 321 MPGRRWSDGLHQAIEAKEGVEITPESQTLASITYQNFFRLYPKLSGMTGTAKTEAEEF 378
|
|
| DEXDc_SecA |
cd17928 |
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the ... |
38-398 |
2.44e-93 |
|
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the vast majority of bacterial and ER-exported proteins. SecA binds both the signal sequence and the mature domain of the preprotein emerging from the ribosome. SecA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350686 [Multi-domain] Cd Length: 230 Bit Score: 291.36 E-value: 2.44e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 38 ALKAMTKEFKKRLNKpRESLDTILPEAYAVVREASRRVLGMYPKDVQVLGAIVLHEGNIAEMQTGEGKTLTATMPLYLNA 117
Cdd:cd17928 1 ELRAKTDELRERLAK-GETLDDLLPEAFALVREAARRVLGMRPFDVQLIGGLVLHEGKIAEMKTGEGKTLTATLPAYLNA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 118 LTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTTSLGFVDIPDYEYQKNekamlYKHDIVYTTNGRLGFDYLIDNLADSI 197
Cdd:cd17928 80 LTGKGVHVVTVNDYLARRDAEWMGPLYEFLGLTVGVILSDMSPDERREA-----YAADITYGTNNELGFDYLRDNMVTSK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 198 EGKFLPKLNYGIIDEVDSIILDAAQTPLVISGaprvqsnlfhivktfvetlekdihfkvkkakkeiwlteagieaanqyf 277
Cdd:cd17928 155 EDLVQRGLNFAIVDEVDSILIDEARTPLIISG------------------------------------------------ 186
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 278 nvsdiydepyfdlarninlalrahhlfesnldyfvyngevvlidritgrmlpgtklqsglhqaieakeqidisldmsVMA 357
Cdd:cd17928 187 -----------------------------------------------------------------------------TLA 189
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 973245241 358 TITFQNLFKQFEDFAGMTGTGKMDEPEFFNLYSKIVIQIPT 398
Cdd:cd17928 190 TITFQNYFRLYPKLAGMTGTAKTEAEEFREIYNLDVVVIPT 230
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| secA2 |
TIGR03714 |
accessory Sec system translocase SecA2; Members of this protein family are homologous to SecA ... |
9-771 |
0e+00 |
|
accessory Sec system translocase SecA2; Members of this protein family are homologous to SecA and part of the accessory Sec system. This system, including both five core proteins for export and a variable number of proteins for glycosylation, operates in certain Gram-positive pathogens for the maturation and delivery of serine-rich glycoproteins such as the cell surface glycoprotein GspB in Streptococcus gordonii. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 163426 [Multi-domain] Cd Length: 762 Bit Score: 1228.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 9 INNMRLRRLQKKLDQINRLGETFVTYSNQALKAMTKEFKKRLNKpRESLDTILPEAYAVVREASRRVLGMYPKDVQVLGA 88
Cdd:TIGR03714 1 INNLRLKKLRKILNKINALKGKMATLSDEELQAKTAEFKNRLVE-GESLDDILPEAYAVVREADKRVLGMFPYDVQVLGA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 89 IVLHEGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTTSLGFVDIPDYEYQKNEK 168
Cdd:TIGR03714 80 IVLHQGNIAEMKTGEGKTLTATMPLYLNALTGKGAMLVTTNDYLAKRDAEEMGPVYEWLGLTVSLGVVDDPDEEYDANEK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 169 AMLYKHDIVYTTNGRLGFDYLIDNLADSIEGKFLPKLNYGIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETL 248
Cdd:TIGR03714 160 RKIYNSDIVYTTNSALGFDYLIDNLASNKEGKFLRPFNYVIVDEVDSVLLDSAQTPLVISGAPRVQSNLYHIADTFVRTL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 249 EKDIHFKVKKAKKEIWLTEAGIEAANQYFNVSDIYDEPYFDLARNINLALRAHHLFESNLDYFVYNGEVVLIDRITGRML 328
Cdd:TIGR03714 240 KEDVDYIFKKDKKEVWLTDKGIEKAEQYFKIDNLYSEEYFELVRHINLALRAHYLFKRNKDYVVTNGEVVLLDRITGRLL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 329 PGTKLQSGLHQAIEAKEQIDISLDMSVMATITFQNLFKQFEDFAGMTGTGKMDEPEFFNLYSKIVIQIPTDRPVQRIDYD 408
Cdd:TIGR03714 320 EGTKLQSGIHQAIEAKEHVELSKETRAMASITYQNLFKMFNKLSGMTGTGKVAEKEFIETYSLSVVKIPTNKPIIRIDYP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 409 DRVFKTEADKNQAIIDKVQELHAQKRPILLITRTAEAAEKFSSTLFKMDIPNNLLIAQNVAKEAQMIAEAGQLAAVTVAT 488
Cdd:TIGR03714 400 DKIYATLPEKLMATLEDVKEYHETGQPVLLITGSVEMSEIYSELLLREGIPHNLLNAQNAAKEAQIIAEAGQKGAVTVAT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 489 SMAGRGTDIKLHPEVQDLGGLAVIINEHMENSHVDRQLRGRSGRQGDPGMSQIYISLEDYLVKRWGDDKLTENERLTAMD 568
Cdd:TIGR03714 480 SMAGRGTDIKLGKGVAELGGLAVIGTERMENSRVDLQLRGRSGRQGDPGSSQFFVSLEDDLIKRWSPSWLKKYYKKYSVK 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 569 ADRLESSGVFKRRVKHIVKKAQRLSEEQGMNAREMANDYEKSISLQRELIYDERDRVLNLEHIDEIEFDTLAKEVFRRDY 648
Cdd:TIGR03714 560 DSKLKPSALFKRRFRKIVEKAQRASEDKGESAREQTNEFEESLSIQRENIYAERNRLIEGSDFLDDDVDQIIDDVFNMYA 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 649 IQAEPLTPRTLTEYIYRNISFQFDQDLSTLDISDHHAVIQFLLDLFKSQLETQRQTINDPYFYQRFLQKTILKSIDTTWI 728
Cdd:TIGR03714 640 EEQDLSNKSLLKRFILENLSYQFKNDPDEFDLKNKEAIKDFLKEIADKELSEKKKVLNNDYLFNDFERLSILKAIDENWI 719
|
730 740 750 760
....*....|....*....|....*....|....*....|...
gi 973245241 729 DQVDHLQQLKASVRNRQNGQRNAIFEYHKVALESYEVMCNKIK 771
Cdd:TIGR03714 720 EQVDYLQQLKTVVTNRQNGQRNPIFEYHKEALESYEYMKKEIK 762
|
|
| PRK09200 |
PRK09200 |
preprotein translocase subunit SecA; Reviewed |
1-796 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 236408 [Multi-domain] Cd Length: 790 Bit Score: 1187.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 1 MKQQINTTINNMRLRRLQKKLDQINRLGETFVTYSNQALKAMTKEFKKRLNKpRESLDTILPEAYAVVREASRRVLGMYP 80
Cdd:PRK09200 1 MKKKLLGDIDKRRLKKYRKIVKQINKLEGKMSSLSDEELRQKTIEFKERLAS-GKTLDDILPEAFAVVREAAKRVLGMRP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 81 KDVQVLGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTTSLGFVDIPD 160
Cdd:PRK09200 80 YDVQLIGALVLHEGNIAEMQTGEGKTLTATMPLYLNALEGKGVHLITVNDYLAKRDAEEMGQVYEFLGLTVGLNFSDIDD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 161 yeyqKNEKAMLYKHDIVYTTNGRLGFDYLIDNLADSIEGKFLPKLNYGIIDEVDSIILDAAQTPLVISGAPRVQSNLFHI 240
Cdd:PRK09200 160 ----ASEKKAIYEADIIYTTNSELGFDYLRDNLADSKEDKVQRPLNYAIIDEIDSILLDEAQTPLIISGKPRVQSNLYHI 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 241 VKTFVETLEKDIHFKVKKAKKEIWLTEAGIEAANQYFNVSDIYDEPYFDLARNINLALRAHHLFESNLDYFVYNGEVVLI 320
Cdd:PRK09200 236 AAKFVKTLEEDVDYEFDEEKKEVWLTDQGIEKAESYFGIDNLYSLEHQVLYRHIILALRAHVLFKRDVDYIVYDGEIVLV 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 321 DRITGRMLPGTKLQSGLHQAIEAKEQIDISLDMSVMATITFQNLFKQFEDFAGMTGTGKMDEPEFFNLYSKIVIQIPTDR 400
Cdd:PRK09200 316 DRFTGRVLPGRKLQDGLHQAIEAKEGVEITEENRTMASITIQNLFRMFPKLSGMTGTAKTEEKEFFEVYNMEVVQIPTNR 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 401 PVQRIDYDDRVFKTEADKNQAIIDKVQELHAQKRPILLITRTAEAAEKFSSTLFKMDIPNNLLIAQNVAKEAQMIAEAGQ 480
Cdd:PRK09200 396 PIIRIDYPDKVFVTLDEKYKAVIEEVKERHETGRPVLIGTGSIEQSETFSKLLDEAGIPHNLLNAKNAAKEAQIIAEAGQ 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 481 LAAVTVATSMAGRGTDIKLHPEVQDLGGLAVIINEHMENSHVDRQLRGRSGRQGDPGMSQIYISLEDYLVKRWGDDKLTE 560
Cdd:PRK09200 476 KGAVTVATNMAGRGTDIKLGEGVHELGGLAVIGTERMESRRVDLQLRGRSGRQGDPGSSQFFISLEDDLLKRFAPEELEK 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 561 NERLTAMDADRLESSgVFKRRVKHIVKKAQRLSEEQGMNAREMANDYEKSISLQRELIYDERDRVLNLEHIDEIEFDTLA 640
Cdd:PRK09200 556 LKKKLKTDAQRLTGL-LFNRKVHKIVVKAQRISEGAGYSAREYALELDDVINIQRDVVYKERNRLLEEDDRDLIDIVILM 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 641 KEVFRRDYIQAEPLTPRTLTEYIYRNISFQFDQDLSTLDISDHHAVIQFLLDLFKSQLETQRQTINDPYFYQRFLQKTIL 720
Cdd:PRK09200 635 IDVYLEAVAEEYLLEKSLLEEWIYENLSFQLNEILSNTNFPDKKEVVQFLLEEAEKQLKEKRNKLPSATLYNQFLRKVAL 714
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 973245241 721 KSIDTTWIDQVDHLQQLKASVRNRQNGQRNAIFEYHKVALESYEVMCNKIKGNIIRNLSQSMATFDKDGDLVIHFP 796
Cdd:PRK09200 715 KAIDQNWVEQVDALQQLKEGIGLRQYGQRNPIREYQKEALESFEYMYENIKKDMVRNLLLSLLVFDKEGEIVIHFP 790
|
|
| PRK12904 |
PRK12904 |
preprotein translocase subunit SecA; Reviewed |
10-780 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237259 [Multi-domain] Cd Length: 830 Bit Score: 708.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 10 NNMRLRRLQKKLDQINRLGETFVTYSNQALKAMTKEFKKRLNKPrESLDTILPEAYAVVREASRRVLGMYPKDVQVLGAI 89
Cdd:PRK12904 13 NDRELKRLRKIVDKINALEPEMEKLSDEELKAKTAEFKERLAKG-ETLDDLLPEAFAVVREASKRVLGMRHFDVQLIGGM 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 90 VLHEGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTTSLGFVDIPDYEYQKNeka 169
Cdd:PRK12904 92 VLHEGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLSVGVILSGMSPEERREA--- 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 170 mlYKHDIVYTTNGRLGFDYLIDNLADSIEGKFLPKLNYGIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETLE 249
Cdd:PRK12904 169 --YAADITYGTNNEFGFDYLRDNMVFSLEERVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDSSELYKRANKIVPTLE 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 250 KDIHFKVKKAKKEIWLTEAGIEAANQYFNVSDIYDEPYFDLARNINLALRAHHLFESNLDYFVYNGEVVLIDRITGRMLP 329
Cdd:PRK12904 247 KEGDYTVDEKSRTVGLTEEGIEKAEKLLGIENLYDPENIALVHHLNQALRAHELFKRDVDYIVKDGEVVIVDEFTGRLMP 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 330 GTKLQSGLHQAIEAKEQIDISLDMSVMATITFQNLFKQFEDFAGMTGTGKMDEPEFFNLYSKIVIQIPTDRPVQRIDYDD 409
Cdd:PRK12904 327 GRRYSDGLHQAIEAKEGVKIQNENQTLASITFQNYFRMYEKLAGMTGTADTEAEEFREIYNLDVVVIPTNRPMIRIDHPD 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 410 RVFKTEADKNQAIIDKVQELHAQKRPILLITRTAEAAEKFSSTLFKMDIPNNLLIAQNVAKEAQMIAEAGQLAAVTVATS 489
Cdd:PRK12904 407 LIYKTEKEKFDAVVEDIKERHKKGQPVLVGTVSIEKSELLSKLLKKAGIPHNVLNAKNHEREAEIIAQAGRPGAVTIATN 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 490 MAGRGTDIKL------------------------------HPEVQDLGGLAVIINEHMENSHVDRQLRGRSGRQGDPGMS 539
Cdd:PRK12904 487 MAGRGTDIKLggnpemlaaalleeeteeqiakikaewqeeHEEVLEAGGLHVIGTERHESRRIDNQLRGRSGRQGDPGSS 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 540 QIYISLEDYLVKRWGddklteNERLTAMDaDRL--------ESSGVFKRrvkhiVKKAQRLSEEQGMNAR-------EMA 604
Cdd:PRK12904 567 RFYLSLEDDLMRIFG------SDRVKGMM-DRLgmkegeaiEHKMVTRA-----IENAQKKVEGRNFDIRkqlleydDVM 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 605 NDyeksislQRELIYDERDRVLNLEHIDEIEFDtlakevFRRDYIQA------------EPLTPRTLTEYIYRNISFQFD 672
Cdd:PRK12904 635 ND-------QRKVIYAQRNEILEGEDLSETILD------MREDVIEDlvdayippgsyeEDWDLEGLEEALKTDFGLELP 701
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 673 QDLSTLDISDHHAVIQFLLDLFKSQLETQRQTINDPYFyqRFLQKTI-LKSIDTTWIDQVDHLQQLKASVRNRQNGQRNA 751
Cdd:PRK12904 702 IEEWLEEGLDEEELRERILEAAEEAYEEKEEELGEEQM--REFERVVmLQVLDTKWREHLAAMDHLRQGIGLRGYAQKDP 779
|
810 820
....*....|....*....|....*....
gi 973245241 752 IFEYHKVALESYEVMCNKIKGNIIRNLSQ 780
Cdd:PRK12904 780 LQEYKREGFELFEEMLDSIKEEVVRTLMK 808
|
|
| secA |
TIGR00963 |
preprotein translocase, SecA subunit; The proteins SecA-F and SecY, not all of which are ... |
24-770 |
0e+00 |
|
preprotein translocase, SecA subunit; The proteins SecA-F and SecY, not all of which are necessary, comprise the standard prokaryotic protein translocation apparatus. Other, specialized translocation systems also exist but are not as broadly distributed. This model describes SecA, an essential member of the apparatus. This model excludes SecA2 of the accessory secretory system. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273366 [Multi-domain] Cd Length: 742 Bit Score: 702.86 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 24 INRLGETFVTYSNQALKAMTKEFKKRLNKPRESLDTILPEAYAVVREASRRVLGMYPKDVQVLGAIVLHEGNIAEMQTGE 103
Cdd:TIGR00963 1 INALEEDYEKLSDEELRNKTNEFKDRLAKQGETLDDLLPEAFAVVREASKRVLGMRPFDVQLIGGIALHKGKIAEMKTGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 104 GKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTTSLGFVDIPDYEYQKNekamlYKHDIVYTTNGR 183
Cdd:TIGR00963 81 GKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAEWMGQVYRFLGLSVGLILSGMSPEERREA-----YACDITYGTNNE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 184 LGFDYLIDNLADSIEGKFLPKLNYGIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETLEKDIHFKVKKAKKEI 263
Cdd:TIGR00963 156 LGFDYLRDNMAHSKEEKVQRPFHFAIIDEVDSILIDEARTPLIISGPAEKSTELYVQANKFAKALEKEVDYEVDEKNRAV 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 264 WLTEAGIEAANQYFNVSDIYDEPYFDLARNINLALRAHHLFESNLDYFVYNGEVVLIDRITGRMLPGTKLQSGLHQAIEA 343
Cdd:TIGR00963 236 LLTEQGMKKAEDLLGVDNLYDLENSPLIHYINNALKAKELFQKDVDYIVRDGEVVIVDEFTGRIMEGRRWSDGLHQAIEA 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 344 KEQIDISLDMSVMATITFQNLFKQFEDFAGMTGTGKMDEPEFFNLYSKIVIQIPTDRPVQRIDYDDRVFKTEADKNQAII 423
Cdd:TIGR00963 316 KEGVEIQNENQTLATITYQNFFRLYEKLSGMTGTAKTEEEEFRKIYNLEVVVVPTNRPVIRKDRPDLVYKTEEEKWKAVV 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 424 DKVQELHAQKRPILLITRTAEAAEKFSSTLFKMDIPNNLLIAQNVAKEAQMIAEAGQLAAVTVATSMAGRGTDIKLHpEV 503
Cdd:TIGR00963 396 EEIKERHAKGQPVLVGTTSVEKSELLSNLLKERGIPHNVLNAKNHEREAEIIAQAGRKGAVTIATNMAGRGTDIKLE-EV 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 504 QDLGGLAVIINEHMENSHVDRQLRGRSGRQGDPGMSQIYISLEDYLVKRWGDDKL-TENERLTAMDADRLESSGVFKrrv 582
Cdd:TIGR00963 475 KELGGLYVIGTERHESRRIDNQLRGRSGRQGDPGSSRFFLSLEDNLMRIFGGDRLeGLMRRLGMDDDEPIESKMVSR--- 551
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 583 khIVKKAQRLSEEQGMNAREMANDYEKSISLQRELIYDERDRVLNLEHIDEIeFDTLAKEV-------FRRDYIQAEPLT 655
Cdd:TIGR00963 552 --ALESAQKRVEGRNFDIRKQLLEYDDVLNKQREVIYAERRRVLESEDLSEL-ILQMLESTldrivdaYINEEKLSEEWD 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 656 PRTLTEYIyrNISFQFDQDLSTLDISD--HHAVIQFLLDLFKSQLETQRQTINDPYFyQRFLQKTILKSIDTTWIDQVDH 733
Cdd:TIGR00963 629 LEGLIEKL--KTLFLLDGDLTPEDLENltSEDLKELLLEKIRAAYDEKEEQLESERM-REFERYVLLQSIDRKWKEHLDA 705
|
730 740 750
....*....|....*....|....*....|....*..
gi 973245241 734 LQQLKASVRNRQNGQRNAIFEYHKVALESYEVMCNKI 770
Cdd:TIGR00963 706 MDLLREGIGLRSYGQKDPLIEYKNEGFNLFEEMLEDI 742
|
|
| SecA |
COG0653 |
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, ... |
10-779 |
0e+00 |
|
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440418 [Multi-domain] Cd Length: 876 Bit Score: 695.62 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 10 NNMRLRRLQKKLDQINRLGETFVTYSNQALKAMTKEFKKRLNKpRESLDTILPEAYAVVREASRRVLGMYPKDVQVLGAI 89
Cdd:COG0653 13 NDRELKRLRKIVDKINALEPEMEALSDEELRAKTDEFKERLAN-GETLDDLLPEAFAVVREASKRVLGMRHFDVQLIGGI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 90 VLHEGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTTSLGFVDIPDYEYQKNeka 169
Cdd:COG0653 92 VLHQGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGRLYRFLGLSVGVIVHGMDPEERRAA--- 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 170 mlYKHDIVYTTNGRLGFDYLIDNLADSIEGKFLPKLNYGIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETLE 249
Cdd:COG0653 169 --YAADITYGTNNEFGFDYLRDNMVFSLEDMVQRGLNYAIVDEVDSILIDEARTPLIISGPAEDSTDLYYRINKLVPRLK 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 250 KDIHFKVKKAKKEIWLTEAGIEAANQYFNVSDIYDEPYFDLARNINLALRAHHLFESNLDYFVYNGEVVLIDRITGRMLP 329
Cdd:COG0653 247 RDGDYTVDEKARTVTLTEEGIEKVEKLLGIDNLYDPENIELVHHLNQALRAHALFKRDVDYIVKDGEVVIVDEFTGRLMP 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 330 GTKLQSGLHQAIEAKEQIDISLDMSVMATITFQNLFKQFEDFAGMTGTGKMDEPEFFNLYSKIVIQIPTDRPVQRIDYDD 409
Cdd:COG0653 327 GRRYSDGLHQAIEAKEGVKIQNENQTLASITFQNYFRMYEKLAGMTGTADTEAEEFREIYGLDVVVIPTNRPMIRKDEPD 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 410 RVFKTEADKNQAIIDKVQELHAQKRPILLITRTAEAAEKFSSTLFKMDIPNNLLIAQNVAKEAQMIAEAGQLAAVTVATS 489
Cdd:COG0653 407 LVYKTEEEKFNAVVEDIKERHEKGQPVLVGTTSIEKSELLSKLLKKEGIPHNVLNAKQHEREAEIVAQAGRPGAVTIATN 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 490 MAGRGTDIKL---------------------------------HPEVQDLGGLAVIINEHMENSHVDRQLRGRSGRQGDP 536
Cdd:COG0653 487 MAGRGTDIVLggnpeflaaaeladrgleweeaiakikaewqaeHEEVLEAGGLHVIGTERHESRRIDNQLRGRSGRQGDP 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 537 GMSQIYISLEDYLVKRWGDDKLtEN--ERLtAMDAD-RLESSGVFKRrvkhiVKKAQRLSEeqGMNArEM---------- 603
Cdd:COG0653 567 GSSRFYLSLEDDLMRIFGSDRI-KGmmDKL-GMEEGePIEHKMVSKA-----IENAQKKVE--GRNF-DIrknlleyddv 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 604 ANDyeksislQRELIYDERDRVLNLEHIDEIEFDtlakevFRRDYIQA--EPLTPR----------TLTEYIYRNISFQF 671
Cdd:COG0653 637 MND-------QRKVIYEQRREILEGEDLSETILD------MREDVIEDlvDEYIPEgsypeqwdleGLEEALKELFGLDL 703
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 672 D-QDLSTLDISDHHAVIQFLLDLFKSQLETQRQTINDPYFyqRFLQKTI-LKSIDTTWIDQVDHLQQLKASVRNRQNGQR 749
Cdd:COG0653 704 PiEEWLDEEGLDEEELRERLLEAADEAYEEKEEELGPEVM--RELERVVlLQVLDRKWREHLDAMDHLRQGIGLRGYAQK 781
|
810 820 830
....*....|....*....|....*....|
gi 973245241 750 NAIFEYHKVALESYEVMCNKIKGNIIRNLS 779
Cdd:COG0653 782 DPLVEYKREAFELFEEMLDSIKEEVVRYLF 811
|
|
| secA |
PRK12906 |
preprotein translocase subunit SecA; Reviewed |
10-781 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237260 [Multi-domain] Cd Length: 796 Bit Score: 687.21 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 10 NNMRLRRLQKKLDQINRLGETFVTYSNQALKAMTKEFKKRLnKPRESLDTILPEAYAVVREASRRVLGMYPKDVQVLGAI 89
Cdd:PRK12906 12 DKRELKRLEKIADKVNALEDEYEKLSDEQLQAKTPEFRDRI-KDGESLDDLLPEAFAVAREGAKRVLGLRPFDVQIIGGI 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 90 VLHEGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTtslgfVDIPDYEYQKNEKA 169
Cdd:PRK12906 91 VLHEGNIAEMKTGEGKTLTATLPVYLNALTGKGVHVVTVNEYLSSRDATEMGELYRWLGLT-----VGLNLNSMSPDEKR 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 170 MLYKHDIVYTTNGRLGFDYLIDNLADSIEGKFLPKLNYGIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETLE 249
Cdd:PRK12906 166 AAYNCDITYSTNSELGFDYLRDNMVVYKEQMVQRPLNYAIVDEVDSILIDEARTPLIISGQAEKATDLYIRADRFVKTLI 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 250 KD-----------IHFKVKKAKKEIWLTEAGIEAANQYFNVSDIYDEPYFDLARNINLALRAHHLFESNLDYFVYNGEVV 318
Cdd:PRK12906 246 KDeaedgdddedtGDYKIDEKTKTISLTEQGIRKAEKLFGLDNLYDSENTALAHHIDQALRANYIMLKDIDYVVQDGEVL 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 319 LIDRITGRMLPGTKLQSGLHQAIEAKEQIDISLDMSVMATITFQNLFKQFEDFAGMTGTGKMDEPEFFNLYSKIVIQIPT 398
Cdd:PRK12906 326 IVDEFTGRVMEGRRYSDGLHQAIEAKEGVKIQEENQTLATITYQNFFRMYKKLSGMTGTAKTEEEEFREIYNMEVITIPT 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 399 DRPVQRIDYDDRVFKTEADKNQAIIDKVQELHAQKRPILLITRTAEAAEKFSSTLFKMDIPNNLLIAQNVAKEAQMIAEA 478
Cdd:PRK12906 406 NRPVIRKDSPDLLYPTLDSKFNAVVKEIKERHAKGQPVLVGTVAIESSERLSHLLDEAGIPHAVLNAKNHAKEAEIIMNA 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 479 GQLAAVTVATSMAGRGTDIKLHPEVQDLGGLAVIINEHMENSHVDRQLRGRSGRQGDPGMSQIYISLEDYLVKRWGDDKL 558
Cdd:PRK12906 486 GQRGAVTIATNMAGRGTDIKLGPGVKELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDDLMRRFGSDRV 565
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 559 TEN-ERLTAMDADR-LESsgvfkRRVKHIVKKAQRLSEEQGMNAREMANDYEKSISLQRELIYDERDRVLNL-----EHI 631
Cdd:PRK12906 566 KAFlDRLGMNDDDQvIES-----RMITRQVESAQKRVEGNNYDTRKQLLQYDDVMREQREVIYKQRMQVINEdkdlkEVL 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 632 DEIEFDTLAKEVfrRDYIQAEPLTPR--TLTEYIYRNISFQFDQDLSTLDISDHHAVIQFLLDLFKSQLETQRQTINDPY 709
Cdd:PRK12906 641 MPMIKRTVDRQV--QMYTQGDKKDWDldALRDFIVSAMPDEETFDFEDLKGKSPEELKKRLLDIVEDNYAEKEKQLGDPT 718
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 973245241 710 FYQRFLQKTILKSIDTTWIDQVDHLQQLKASVRNRQNGQRNAIFEYHKVALESYEVMCNKIKGNIIRNLSQS 781
Cdd:PRK12906 719 QMLEFEKVVILRVVDSHWTDHIDAMDQLRQSIGLRGYGQLNPLVEYQEEGYRMFEEMISNIDYDVTRLFMKA 790
|
|
| secA |
PRK12903 |
preprotein translocase subunit SecA; Reviewed |
1-779 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237258 [Multi-domain] Cd Length: 925 Bit Score: 603.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 1 MKQQINTTINNMRLRRLQKKLDQINRLGETFVTYSNQALKAMTKEFKKRLnKPRESLDTILPEAYAVVREASRRVLGMYP 80
Cdd:PRK12903 1 MKFLKLFFFKSTEMRIAEKILKQINDLEPYYRNLTDEELANKTNEFKDRL-KNGETLEDIRVEAFAVAREATKRVLGKRP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 81 KDVQVLGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTTSLGFVDIPd 160
Cdd:PRK12903 80 YDVQIIGGIILDLGSVAEMKTGEGKTITSIAPVYLNALTGKGVIVSTVNEYLAERDAEEMGKVFNFLGLSVGINKANMD- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 161 yeyqKNEKAMLYKHDIVYTTNGRLGFDYLIDNLADSIEGKFLPKLNYGIIDEVDSIILDAAQTPLVISGAPRVQSNLFHI 240
Cdd:PRK12903 159 ----PNLKREAYACDITYSVHSELGFDYLRDNMVSSKEEKVQRGLNFCLIDEVDSILIDEAKTPLIISGGQSNDSNLYLA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 241 VKTFVETLEKDiHFKVKKAKKEIWLTEAGIEAANQYFNVSDIYDEPYFDLARNINLALRAHHLFESNLDYFVYNGEVVLI 320
Cdd:PRK12903 235 ADQFVRTLKED-DYKIDEETKAISLTEKGIKKANKFFKLKNLYDIENSELVHRIQNALRAHKVMKEDVEYIVRDGKIELV 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 321 DRITGRMLPGTKLQSGLHQAIEAKEQIDISLDMSVMATITFQNLFKQFEDFAGMTGTGKMDEPEFFNLYSKIVIQIPTDR 400
Cdd:PRK12903 314 DQFTGRIMEGRSYSEGLQQAIQAKEMVEIEPETKTLATITYQNFFRLFKKLSGMTGTAKTEEQEFIDIYNMRVNVVPTNK 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 401 PVQRIDYDDRVFKTEADKNQAIIDKVQELHAQKRPILLITRTAEAAEKFSSTLFKMDIPNNLLIAQNVAKEAQMIAEAGQ 480
Cdd:PRK12903 394 PVIRKDEPDSIFGTKHAKWKAVVKEVKRVHKKGQPILIGTAQVEDSETLHELLLEANIPHTVLNAKQNAREAEIIAKAGQ 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 481 LAAVTVATSMAGRGTDIKLHPEVQDLGGLAVIINEHMENSHVDRQLRGRSGRQGDPGMSQIYISLEDYLVKRW-GDDKLt 559
Cdd:PRK12903 474 KGAITIATNMAGRGTDIKLSKEVLELGGLYVLGTDKAESRRIDNQLRGRSGRQGDVGESRFFISLDDQLFRRFsNFDKI- 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 560 enERLTAMDADRLESSGVFKRrvkhIVKKAQRLSEeqGMN--AREMANDYEKSISLQRELIYDERDRVL---NLEHIDEI 634
Cdd:PRK12903 553 --KEAFKKLGDDEIKSKFFSK----ALLNAQKKIE--GFNfdTRKNVLDYDDVIRQQRDLIYAQRDLILiadDLSHVIEK 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 635 EFDTLAKEVFRRDYIQA--EPLTPRTLTEYIYRNISFQFDQDLSTLDISDHH--AVIQFLLDLFKSQLETQRQTINDPYF 710
Cdd:PRK12903 625 MISRAVEQILKNSFIILknNTINYKELVEFLNDNLLRITHFKFSEKDFENYHkeELAQYLIEALNEIYFKKRQVILDKIA 704
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 973245241 711 YQRFLQ---KTILKSIDTTWIDQVDHLQQLKASVRNRQNGQRNAIFEYHKVALESYEVMCNKIKGNIIRNLS 779
Cdd:PRK12903 705 LNTFFEserYIILSALDKYWQNHIDTMDKLRSGVNLVQYSQKNPYQVYTEEGTKKFNILLQEIAYDVIVSLF 776
|
|
| secA |
CHL00122 |
preprotein translocase subunit SecA; Validated |
9-784 |
0e+00 |
|
preprotein translocase subunit SecA; Validated
Pssm-ID: 214371 [Multi-domain] Cd Length: 870 Bit Score: 584.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 9 INNMRLRRLQKKLDQINRLGETFVTYSNQALKAMTKEFKKRLNKpRESLDTILPEAYAVVREASRRVLGMYPKDVQVLGA 88
Cdd:CHL00122 7 NNKSKLNKYQTLVNQINLLEEELKNLTDTELRSKTNKLKKRLSN-GQNLNKIIPESFALTREASFRTLGLRHFDVQLIGG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 89 IVLHEGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTTSLGFVDIPDYEYQKNek 168
Cdd:CHL00122 86 LVLNDGKIAEMKTGEGKTLVATLPAYLNALTGKGVHIVTVNDYLAKRDQEWMGQIYRFLGLTVGLIQEGMSSEERKKN-- 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 169 amlYKHDIVYTTNGRLGFDYLIDNLADSIEGKFLPKLNYGIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETL 248
Cdd:CHL00122 164 ---YLKDITYVTNSELGFDYLRDNMALSLSDVVQRPFNYCIIDEVDSILIDEARTPLIISGQSKTNIDKYIVADELAKYL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 249 EKDIHFKVKKAKKEIWLTEAGIEAANQYFNVSDIYDE-----PYFdlarnINlALRAHHLFESNLDYFVYNGEVVLIDRI 323
Cdd:CHL00122 241 EKNVHYEVDEKNKNVILTEQGILFIEKILKIEDLYSAndpwiPYI-----LN-ALKAKELFFKNVHYIVRNNEIIIVDEF 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 324 TGRMLPGTKLQSGLHQAIEAKEQIDISLDMSVMATITFQNLFKQFEDFAGMTGTGKMDEPEFFNLYSKIVIQIPTDRPVQ 403
Cdd:CHL00122 315 TGRIMPGRRWSDGLHQAIEAKENLPIRQETETLASITYQNFFLLYPKLSGMTGTAKTEELEFEKIYNLEVVCIPTHRPML 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 404 RIDYDDRVFKTEADKNQAIIDKVQELHAQKRPILLITRTAEAAEKFSSTLFKMDIPNNLLIA--QNVAKEAQMIAEAGQL 481
Cdd:CHL00122 395 RKDLPDLIYKDELSKWRAIADECLQMHQTGRPILIGTTTIEKSELLSQLLKEYRLPHQLLNAkpENVRRESEIVAQAGRK 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 482 AAVTVATSMAGRGTDIKL-------------------------------------------------------------- 499
Cdd:CHL00122 475 GSITIATNMAGRGTDIILggnpefklkkelydlllsyksnekistisqnflnilnslkndlkflslsdfenlkilnease 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 500 ------HPE------------------------VQDLGGLAVIINEHMENSHVDRQLRGRSGRQGDPGMSQIYISLEDYL 549
Cdd:CHL00122 555 isipknSYQlslrflynellekykklqekekkiVKKLGGLYVIGTERHESRRIDNQLRGRAGRQGDPGSSRFFLSLEDNL 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 550 VKRWGDDKLTEnerltAMDADRLESSGVFKRRVKHIVKKAQRLSEEQGMNAREMANDYEKSISLQRELIYDERDRVLNLE 629
Cdd:CHL00122 635 LRIFGGDKIQN-----LMQTLNLDDEPLESKLLSKSLDSAQKKVEEYYYDQRKQLFEYDQVLNKQRKAIYSERRKILESQ 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 630 HIDE--IEF--DTLAKEVFRRDYIQAEPLTPRTLTEYIYRNISFQFDQDLSTLDISDHHAVIQFLL-------DLFKSQL 698
Cdd:CHL00122 710 SLRDwiLAYgeQVIDDIITFLKSRKNPNNKFINLINKFKELLKLPLCFNKSDLNTLNSGELKKFLYqqfwisyDLKELYL 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 699 EtqrqtINDPYFYQRFLQKTILKSIDTTWidqVDHLQQ---LKASVRNRQNGQRNAIFEYHKVALESYEVMCNKIKGNII 775
Cdd:CHL00122 790 E-----QIGTGLMRELERSLLLQQIDKSW---KEHLQKmslLREAIGWRSYGQKDPLIEYKNEAFNLFINMINHIRHLVI 861
|
....*....
gi 973245241 776 RNLSQSMAT 784
Cdd:CHL00122 862 YDLFRSSIL 870
|
|
| SecA_DEAD |
smart00957 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
8-386 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the.
Pssm-ID: 214937 [Multi-domain] Cd Length: 380 Bit Score: 558.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 8 TINNMRLRRLQKKLDQINRLGETFVTYSNQALKAMTKEFKKRLNKpRESLDTILPEAYAVVREASRRVLGMYPKDVQVLG 87
Cdd:smart00957 7 SKNDRELKRLRKIVDQINALEPEMEALSDEELRAKTAEFKERLAE-GESLDDLLPEAFAVVREAAKRVLGMRHFDVQLIG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 88 AIVLHEGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTTSLGFVDIPDyeyqkNE 167
Cdd:smart00957 86 GIVLHEGKIAEMKTGEGKTLVATLPAYLNALTGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLTVGVIVSGMSP-----EE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 168 KAMLYKHDIVYTTNGRLGFDYLIDNLADSIEGKFLPKLNYGIIDEVDSIILDAAQTPLVISG-APRVQSNLFHIVKTFVE 246
Cdd:smart00957 161 RRAAYAADITYGTNNEFGFDYLRDNMAFSKEDKVQRGLNYAIVDEVDSILIDEARTPLIISGpAEDESSDLYHRADKFVP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 247 TLEKDIHFKVKKAKKEIWLTEAGIEAANQYFNVSDIYDEPYFDLARNINLALRAHHLFESNLDYFVYNGEVVLIDRITGR 326
Cdd:smart00957 241 RLKEDEDYTVDEKSRTVELTEEGIEKAEKLLGIDNLYDPENIELLHHVNQALRAHYLFKRDVDYIVRDGEVVIVDEFTGR 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 327 MLPGTKLQSGLHQAIEAKEQIDISLDMSVMATITFQNLFKQFEDFAGMTGTGKMDEPEFF 386
Cdd:smart00957 321 VMEGRRYSDGLHQAIEAKEGVEIQEENQTLATITFQNYFRMYKKLSGMTGTAKTEAEEFR 380
|
|
| SecA_DEAD |
pfam07517 |
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with ... |
8-385 |
0e+00 |
|
SecA DEAD-like domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This domain represents the N-terminal ATP-dependent helicase domain, which is related to the pfam00270.
Pssm-ID: 462190 [Multi-domain] Cd Length: 379 Bit Score: 535.92 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 8 TINNMRLRRLQKKLDQINRLGETFVTYSNQALKAMTKEFKKRLnKPRESLDTILPEAYAVVREASRRVLGMYPKDVQVLG 87
Cdd:pfam07517 7 SPNERDLKRLRKIVDQINALEEELKALSDEELRAKTDELRERL-REGESLDDILPEAFALVREAAKRVLGMRHYDVQLIG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 88 AIVLHEGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTTSLGFVDIPDYEYQKNe 167
Cdd:pfam07517 86 GLVLHEGKIAEMKTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAKRDAEWMGPLYEFLGLTVGVITSDMDPEERRAA- 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 168 kamlYKHDIVYTTNGRLGFDYLIDNLADSIEGKFLPKLNYGIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVET 247
Cdd:pfam07517 165 ----YNADITYGTNNELGFDYLRDNMATSKEDKVQRGLNFAIVDEVDSILIDEARTPLIISGPSEDDSELYREADRLVKS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 248 LEKDIHFKVKKAKKEIWLTEAGIEAANQYFNVSDIYDEPYFDLARNINLALRAHHLFESNLDYFVYNGEVVLIDRITGRM 327
Cdd:pfam07517 241 LEEDGDYEIDEKSKNVELTEKGIEKIEKLLGIDNLYDPENVELLHHINQALKAHHLFKRDVDYIVRDGEVVIVDEFTGRV 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 973245241 328 LPGTKLQSGLHQAIEAKEQIDISLDMSVMATITFQNLFKQFEDFAGMTGTGKMDEPEF 385
Cdd:pfam07517 321 MPGRRWSDGLHQAIEAKEGVEITPESQTLASITYQNFFRLYPKLSGMTGTAKTEAEEF 378
|
|
| secA |
PRK12898 |
preprotein translocase subunit SecA; Reviewed |
9-601 |
0e+00 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237253 [Multi-domain] Cd Length: 656 Bit Score: 535.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 9 INNMRLRRLQKKLDQINRLGETFVTYSNQALKAMTKEFKKRLNKPRESLDTILPEAYAVVREASRRVLGMYPKDVQVLGA 88
Cdd:PRK12898 33 VRGRAARRQRLLADRVLAAAEALAGLSEEALRARSLALRARLRARDGFRDALLAEAFALVREASGRVLGQRHFDVQLMGG 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 89 IVLHEGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTTSLGfvdIPDYEYQKNEK 168
Cdd:PRK12898 113 LALLSGRLAEMQTGEGKTLTATLPAGTAALAGLPVHVITVNDYLAERDAELMRPLYEALGLTVGCV---VEDQSPDERRA 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 169 AmlYKHDIVYTTNGRLGFDYLIDNLA-------------------DSIEGKFLPKLNYGIIDEVDSIILDAAQTPLVISG 229
Cdd:PRK12898 190 A--YGADITYCTNKELVFDYLRDRLAlgqrasdarlaleslhgrsSRSTQLLLRGLHFAIVDEADSVLIDEARTPLIISA 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 230 APRVQSNL--FHIVKTFVETLEKDIHFKVKKAKKEIWLTEAGIEAANQYFNVSDIYDEPYFDLARNINLALRAHHLFESN 307
Cdd:PRK12898 268 PAKEADEAevYRQALELAAQLKEGEDYTIDAAEKRIELTEAGRARIAELAESLPPAWRGAVRREELVRQALSALHLFRRD 347
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 308 LDYFVYNGEVVLIDRITGRMLPGTKLQSGLHQAIEAKEQIDISLDMSVMATITFQNLFKQFEDFAGMTGTGKMDEPEFFN 387
Cdd:PRK12898 348 EHYIVRDGKVVIVDEFTGRVMPDRSWEDGLHQMIEAKEGCELTDPRETLARITYQRFFRRYLRLAGMTGTAREVAGELWS 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 388 LYSKIVIQIPTDRPVQRIDYDDRVFKTEADKNQAIIDKVQELHAQKRPILLITRTAEAAEKFSSTLFKMDIPNNLLIAQN 467
Cdd:PRK12898 428 VYGLPVVRIPTNRPSQRRHLPDEVFLTAAAKWAAVAARVRELHAQGRPVLVGTRSVAASERLSALLREAGLPHQVLNAKQ 507
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 468 VAKEAQMIAEAGQLAAVTVATSMAGRGTDIKLHPEVQDLGGLAVIINEHMENSHVDRQLRGRSGRQGDPGMSQIYISLED 547
Cdd:PRK12898 508 DAEEAAIVARAGQRGRITVATNMAGRGTDIKLEPGVAARGGLHVILTERHDSARIDRQLAGRCGRQGDPGSYEAILSLED 587
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....
gi 973245241 548 YLVKRWGDDKLtenerLTAMDADRLESSGvFKRRVKHIVKKAQRLSEEQGMNAR 601
Cdd:PRK12898 588 DLLQSFLGSRG-----LAIRRMELLGPRG-GRALGALLLRRAQRRAERLHARAR 635
|
|
| secA |
PRK12901 |
preprotein translocase subunit SecA; Reviewed |
14-775 |
3.75e-156 |
|
preprotein translocase subunit SecA; Reviewed
Pssm-ID: 237256 [Multi-domain] Cd Length: 1112 Bit Score: 483.75 E-value: 3.75e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 14 LRRLQKKLDQINRLGETFVTYSNQALKAMTKEFKKRLNKPRES------------------------------------- 56
Cdd:PRK12901 17 LKEIQPIVEKIKAEYPELEALSNDELRAKTDEFKQYIKEAVADidakieelkaeaiesldiderediyaqidklekeaye 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 57 -----LDTILPEAYAVVREASRRVLG---------------------------------------------MYPKDVQVL 86
Cdd:PRK12901 97 ilekvLDEILPEAFAIVKETARRFAEneeievtatdfdrelaatkdfvtiegdkaiwknhwdaggneitwdMVHYDVQLI 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 87 GAIVLHEGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTtslgfVDIPDYeYQKN 166
Cdd:PRK12901 177 GGVVLHQGKIAEMATGEGKTLVATLPVYLNALTGNGVHVVTVNDYLAKRDSEWMGPLYEFHGLS-----VDCIDK-HQPN 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 167 EKA--MLYKHDIVYTTNGRLGFDYLIDNLADSIEGKFLPKLNYGIIDEVDSIILDAAQTPLVISG-APRVQSNLFHIVKT 243
Cdd:PRK12901 251 SEArrKAYNADITYGTNNEFGFDYLRDNMAHSPEDLVQRKHNYAIVDEVDSVLIDDARTPLIISGpVPKGDDQEFEELKP 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 244 FVETL---EKDIHFKV-KKAKKEI---------------------------WLTEAGIEAANQ----------------- 275
Cdd:PRK12901 331 RVERLveaQRKLATQFlAEAKKLIaegdkkegglallrayrglpknkalikFLSEEGIKALLQktenfymqdnnrempev 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 276 ----YF------------------------------------NVSDIYDEPYFD----------LARN----------IN 295
Cdd:PRK12901 411 deelYFvideknnsveltdkgidyitgndedpdffvlpdigtELAEIENEGGLDeeeeaekkeeLFQDysvkservhtLN 490
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 296 LALRAHHLFESNLDYFVYNGEVVLIDRITGRMLPGTKLQSGLHQAIEAKEQIDISLDMSVMATITFQNLFKQFEDFAGMT 375
Cdd:PRK12901 491 QLLKAYTLFEKDDEYVVMDGKVKIVDEQTGRIMEGRRYSDGLHQAIEAKENVKIEAATQTFATITLQNYFRMYHKLAGMT 570
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 376 GTGKMDEPEFFNLYSKIVIQIPTDRPVQRIDYDDRVFKTEADKNQAIIDKVQELHAQKRPILLITRTAEAAEKFSSTLFK 455
Cdd:PRK12901 571 GTAETEAGEFWDIYKLDVVVIPTNRPIARKDKEDLVYKTKREKYNAVIEEITELSEAGRPVLVGTTSVEISELLSRMLKM 650
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 456 MDIPNNLLIAQNVAKEAQMIAEAGQLAAVTVATSMAGRGTDIKLHPEVQDLGGLAVIINEHMENSHVDRQLRGRSGRQGD 535
Cdd:PRK12901 651 RKIPHNVLNAKLHQKEAEIVAEAGQPGTVTIATNMAGRGTDIKLSPEVKAAGGLAIIGTERHESRRVDRQLRGRAGRQGD 730
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 536 PGMSQIYISLEDYLVKRWGDDKLTE-NERLTAMDADRLESSGVFKRrvkhiVKKAQRLSEEQGMNAREMANDYEKSISLQ 614
Cdd:PRK12901 731 PGSSQFYVSLEDNLMRLFGSERIAKvMDRMGLKEGEVIQHSMISKS-----IERAQKKVEENNFGIRKRLLEYDDVMNSQ 805
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 615 RELIYDERDRVLNLEH----IDEIEFDTLAK-----------EVFRRDYIQA------------EPLTPRTLTEYIYRNI 667
Cdd:PRK12901 806 REVIYKRRRHALMGERlgmdIANMIYDVCEAivennkvandyKGFKFELIRTlamespiteeefNKLKKDELTDKLYDAA 885
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 668 SFQFDQDLSTL------------------------DISDHHAVIQFLLDLfKSQLETQ-RQTINDpyfyqrfLQKTI-LK 721
Cdd:PRK12901 886 LENYQRKMERIaeiafpvikqvyeeqgnmyerivvPFTDGKRTLNVVTNL-KEAYETEgKEIVKD-------FEKNItLH 957
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....
gi 973245241 722 SIDTTWIDQVDHLQQLKASVRNRQNGQRNAIFEYHKVALESYEVMCNKIKGNII 775
Cdd:PRK12901 958 IIDEAWKEHLREMDELKQSVQNASYEQKDPLLIYKFESFELFKNMVDKVNREVI 1011
|
|
| SecA2_Mycobac |
TIGR04221 |
accessory Sec system translocase SecA2, Actinobacterial type; Members of this family are the ... |
14-789 |
1.74e-134 |
|
accessory Sec system translocase SecA2, Actinobacterial type; Members of this family are the SecA2 subunit of the Mycobacterial type of accessory secretory system. This family is quite different SecA2 of the Staph/Strep type (TIGR03714).
Pssm-ID: 275062 [Multi-domain] Cd Length: 762 Bit Score: 417.30 E-value: 1.74e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 14 LRRLQKKLDQINRLGETFVTYSNQALKAMTKEfkkrLNKPRESLDtiLPEAYAVVREASRRVLGMYPKDVQVLGAIVLHE 93
Cdd:TIGR04221 17 QKRSLAIVPAAASRMKELSALDDEELTKAARD----LVLSGEAAD--AAQFLAILREAAERTLGMRPFDVQLLGALRLLA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 94 GNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTtsLGFVDipdYEYQKNEKAMLYK 173
Cdd:TIGR04221 91 GDVIEMATGEGKTLAGAMAATGFALLGKRVHVVTVNDYLARRDAEWMGPLVDFFGLT--VGWVT---EDSTPDERRAAYA 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 174 HDIVYTTNGRLGFDYLIDNLADSIEGKFLPKLNYGIIDEVDSIILDAAQTPLVISGA-PRVQSNlfHIVKTFVETLEKDI 252
Cdd:TIGR04221 166 CDVTYASVNEIGFDVLRDQLVTDRADLVQPAADVALIDEADSVLVDEALVPLVLAGNePGEAPR--GRITDLVRRLREDK 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 253 HFKVKKAKKEIWLTEAGIEAANQYFNVSDIYDEPYF-DLARNINLALRAHHLFESNLDYFVYNGEVVLIDRITGRMLPGT 331
Cdd:TIGR04221 244 HYTVDEDGRNVHLTEDGARAVEAELGIDDLYSEEHVgTTLVQVNVALHAHALLIRDVHYIVRDGKVALIDASRGRVAQLQ 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 332 KLQSGLHQAIEAKEQIDISLDMSVMATITFQNLFKQFEDFAGMTGTGKMDEPEFFNLYSKIVIQIPTDRPVQRIDYDDRV 411
Cdd:TIGR04221 324 RWPDGLQAAVEAKEGLEVTEGGEVLDTITVQALIGRYPTVCGMTGTAVAAGEQLRQFYDLGVSVIPPNTPNIRFDEADRV 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 412 FKTEADKNQAIIDKVQELHAQKRPILLITRTAEAAEKFSSTLFKMDIPNNLLIAQNVAKEAQMIAEAGQLAAVTVATSMA 491
Cdd:TIGR04221 404 YATAAEKNDAIVEEIAEVHKTGQPVLVGTQDVAESEELAEALLEAGVPCNVLNAKNDAEEAAIIAEAGDIGAVTVSTQMA 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 492 GRGTDIKL-------HPEVQDLGGLAVIINEHMENSHVDRQLRGRSGRQGDPGMSQIYISLEDYLVKRWGD-DKLTENer 563
Cdd:TIGR04221 484 GRGTDIRLggsdeadHDRVAELGGLHVIGTGRHRTARLDNQLRGRAGRQGDPGSSVFFVSLEDDVVAVGGAgETVPAQ-- 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 564 lTAMDAdRLESsgvfkRRVKHIVKKAQRLSEEQGMNAREMANDYEKSISLQRELIYDERDRVLNLehideiefDTLAKEV 643
Cdd:TIGR04221 562 -PAEDG-RIES-----PRVQDFVDHAQRVAEGQLLEIHANTWRYNQLIAQQRDIIDERRETLLDT--------DTAWQEL 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 644 FRRDYIQAEPLT---PRTLTEYIYRNIsfqfdqdlstldisdhhaviqflldlfksqletqrqtindpyfyqrflqktIL 720
Cdd:TIGR04221 627 SERAADRAAELKkevSEDALERAAREI---------------------------------------------------ML 655
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 973245241 721 KSIDTTWIDQVDHLQQLKASVRNRQNGQRNAIFEYHKVALESYevmcNKIKGNIIRNLSQSMAT--FDKDG 789
Cdd:TIGR04221 656 YHLDRGWAEHLAYLDDVRESIHLRALGRETPLDEFHRMAVRAF----KELAQRAVDKAVETFEEveIDADG 722
|
|
| DEXDc_SecA |
cd17928 |
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the ... |
38-398 |
2.44e-93 |
|
DEXD-box helicase domain of SecA; SecA is a part of the Sec translocase that transports the vast majority of bacterial and ER-exported proteins. SecA binds both the signal sequence and the mature domain of the preprotein emerging from the ribosome. SecA belongs to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350686 [Multi-domain] Cd Length: 230 Bit Score: 291.36 E-value: 2.44e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 38 ALKAMTKEFKKRLNKpRESLDTILPEAYAVVREASRRVLGMYPKDVQVLGAIVLHEGNIAEMQTGEGKTLTATMPLYLNA 117
Cdd:cd17928 1 ELRAKTDELRERLAK-GETLDDLLPEAFALVREAARRVLGMRPFDVQLIGGLVLHEGKIAEMKTGEGKTLTATLPAYLNA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 118 LTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTTSLGFVDIPDYEYQKNekamlYKHDIVYTTNGRLGFDYLIDNLADSI 197
Cdd:cd17928 80 LTGKGVHVVTVNDYLARRDAEWMGPLYEFLGLTVGVILSDMSPDERREA-----YAADITYGTNNELGFDYLRDNMVTSK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 198 EGKFLPKLNYGIIDEVDSIILDAAQTPLVISGaprvqsnlfhivktfvetlekdihfkvkkakkeiwlteagieaanqyf 277
Cdd:cd17928 155 EDLVQRGLNFAIVDEVDSILIDEARTPLIISG------------------------------------------------ 186
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 278 nvsdiydepyfdlarninlalrahhlfesnldyfvyngevvlidritgrmlpgtklqsglhqaieakeqidisldmsVMA 357
Cdd:cd17928 187 -----------------------------------------------------------------------------TLA 189
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 973245241 358 TITFQNLFKQFEDFAGMTGTGKMDEPEFFNLYSKIVIQIPT 398
Cdd:cd17928 190 TITFQNYFRLYPKLAGMTGTAKTEAEEFREIYNLDVVVIPT 230
|
|
| SF2_C_secA |
cd18803 |
C-terminal helicase domain of the protein translocase subunit secA; SecA is a component of the ... |
404-544 |
4.61e-69 |
|
C-terminal helicase domain of the protein translocase subunit secA; SecA is a component of the Sec translocase that transports the vast majority of bacterial and ER-exported proteins. SecA binds both the signal sequence and the mature domain of the preprotein emerging from the ribosome. SecA is a DEAD-like helicase belonging to superfamily (SF)2, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350190 [Multi-domain] Cd Length: 141 Bit Score: 223.97 E-value: 4.61e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 404 RIDYDDRVFKTEADKNQAIIDKVQELHAQKRPILLITRTAEAAEKFSSTLFKMDIPNNLLIAQNVAKEAQMIAEAGQLAA 483
Cdd:cd18803 1 RKDLPDLVYKTEEEKWKAIVEEVKELHAKGQPVLVGTRSVEKSELLSALLKEEGIPHNVLNAKNHAREAEIIAEAGQKGA 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 973245241 484 VTVATSMAGRGTDIKLHPEVQDLGGLAVIINEHMENSHVDRQLRGRSGRQGDPGMSQIYIS 544
Cdd:cd18803 81 VTIATNMAGRGTDIKLGGNVEELGGLHVIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLS 141
|
|
| SecA_PP_bind |
smart00958 |
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and ... |
230-342 |
4.59e-39 |
|
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and retraction of preproteins through the plasma membrane. This domain has been found to cross-link to preproteins, thought to indicate a role in preprotein binding. The pre-protein cross-linking domain is comprised of two sub domains that are inserted within the ATPase domain.
Pssm-ID: 214938 [Multi-domain] Cd Length: 114 Bit Score: 140.28 E-value: 4.59e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 230 APRVQSNLFHIVKTFVETLEKDI-HFKVKKAKKEIWLTEAGIEAANQYFNVSDIYDEPYFDLARNINLALRAHHLFESNL 308
Cdd:smart00958 1 PAEDSSELYKRADELVPTLKKDEeDYEVDEKSRQVALTEEGIEKAEKLLGIDNLYDPENIELVHHVNQALRAHKLFKRDV 80
|
90 100 110
....*....|....*....|....*....|....
gi 973245241 309 DYFVYNGEVVLIDRITGRMLPGTKLQSGLHQAIE 342
Cdd:smart00958 81 DYIVRDGEVVIVDEFTGRVMPGRRWSDGLHQAIE 114
|
|
| SecA_PP_bind |
pfam01043 |
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and ... |
233-342 |
1.81e-38 |
|
SecA preprotein cross-linking domain; The SecA ATPase is involved in the insertion and retraction of preproteins through the plasma membrane. This domain has been found to cross-link to preproteins, thought to indicate a role in preprotein binding. The pre-protein cross-linking domain is comprised of two sub domains that are inserted within the ATPase domain.
Pssm-ID: 460039 [Multi-domain] Cd Length: 110 Bit Score: 138.31 E-value: 1.81e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 233 VQSNLFHIVKTFVETLEKDIHFKVKKAKKEIWLTEAGIEAANQYFNVSDIYDEPYFDLARNINLALRAHHLFESNLDYFV 312
Cdd:pfam01043 1 KSTELYRQADKFVKQLKEDEDYEVDEKAKTVELTEEGIEKAEKLLGIDNLYDPENIELVHHINQALKAHHLFKRDVDYIV 80
|
90 100 110
....*....|....*....|....*....|
gi 973245241 313 YNGEVVLIDRITGRMLPGTKLQSGLHQAIE 342
Cdd:pfam01043 81 KDGEVVIVDEFTGRLMPGRRYSDGLHQAIE 110
|
|
| SecA_SW |
pfam07516 |
SecA Wing and Scaffold domain; SecA protein binds to the plasma membrane where it interacts ... |
580-780 |
8.53e-23 |
|
SecA Wing and Scaffold domain; SecA protein binds to the plasma membrane where it interacts with proOmpA to support translocation of proOmpA through the membrane. SecA protein achieves this translocation, in association with SecY protein, in an ATP dependent manner. This family is composed of two C-terminal alpha helical subdomains: the wing and scaffold subdomains.
Pssm-ID: 462189 [Multi-domain] Cd Length: 213 Bit Score: 97.18 E-value: 8.53e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 580 RRVKHIVKKAQRLSEEQGMNAREMANDYEKSISLQRELIYDERDRVLNLEHIDEIeFDTLAKEVFRR---DYIQAEPLTP 656
Cdd:pfam07516 5 KMVSKAIENAQKKVEGRNFDIRKNLLEYDDVMNQQREVIYAQRREILEGEDLKED-ILEMIEDVVDDivdEYIPPEESPE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 657 ----RTLTEYIYRNISFQFD-QDLSTLDISDHHAVIQFLLDLFKSQLETQRQTINDPYFYQrFLQKTILKSIDTTWIDQV 731
Cdd:pfam07516 84 ewdlEGLKEALNEIFGLELPiSEWEEEEDLDKEELKERLLEAAEEAYEEKEEEIGPELMRE-LERVVLLQVIDSKWKEHL 162
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 973245241 732 DHLQQLKASVRNRQNGQRNAIFEYHKVALESYEVMCNKIKGNIIRNLSQ 780
Cdd:pfam07516 163 DAMDQLRQGIGLRAYGQKDPLVEYKREGFELFEEMLDAIREEVVRYLFR 211
|
|
| SF2-N |
cd00046 |
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily ... |
92-226 |
1.84e-12 |
|
N-terminal DEAD/H-box helicase domain of superfamily 2 helicases; The DEAD/H-like superfamily 2 helicases comprise a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This N-terminal domain contains the ATP-binding region.
Pssm-ID: 350668 [Multi-domain] Cd Length: 146 Bit Score: 65.50 E-value: 1.84e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 92 HEGNIAEMQTGEGKTLTATMPLYLNALT-GKGAYLITTNDYLAGRDYEEMKPLYEWlGLTTSL--GFVDIPDYEYQKNEK 168
Cdd:cd00046 1 GENVLITAPTGSGKTLAALLAALLLLLKkGKKVLVLVPTKALALQTAERLRELFGP-GIRVAVlvGGSSAEEREKNKLGD 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 973245241 169 AmlykhDIVYTTNGRLGFDYLIDNLAdsiegkFLPKLNYGIIDEVDSIILDAAQTPLV 226
Cdd:cd00046 80 A-----DIIIATPDMLLNLLLREDRL------FLKDLKLIIVDEAHALLIDSRGALIL 126
|
|
| DEAD-like_helicase_N |
cd17912 |
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase ... |
96-137 |
1.32e-06 |
|
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase superfamily is a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. The N-terminal domain contains the ATP-binding region.
Pssm-ID: 350670 [Multi-domain] Cd Length: 81 Bit Score: 46.74 E-value: 1.32e-06
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 973245241 96 IAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDY 137
Cdd:cd17912 3 LHLGPTGSGKTLVAIQKIASAMSSGKSVLVVTPTKLLAHEIL 44
|
|
| DEAD-like_helicase_C |
cd09300 |
C-terminal helicase domain of the DEAD-like helicases; This hierarchy of DEAD-like helicases ... |
484-542 |
1.90e-04 |
|
C-terminal helicase domain of the DEAD-like helicases; This hierarchy of DEAD-like helicases is composed of two superfamilies, SF1 and SF2, that share almost identical folds and extensive structural similarity in their catalytic core. Helicases are involved in ATP-dependent RNA or DNA unwinding. Two distinct types of helicases exist, those forming toroidal, predominantly hexameric structures, and those that do not. SF1 and SF2 helicases do not form toroidal structures, while SF3-6 helicases do. Their conserved helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350171 [Multi-domain] Cd Length: 59 Bit Score: 39.84 E-value: 1.90e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 973245241 484 VTVATSMAGRGTDIklhpevqdLGGLAVIINEHMENSHVDRQLRGRSGRQGDPGMSQIY 542
Cdd:cd09300 8 VLIAVN*ALTGFDA--------PELNTIIVDKNLRSYRGLNQAFGRANRIYTFGGIVTY 58
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
80-217 |
2.73e-04 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 42.86 E-value: 2.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 80 PKDVQVLGAIVLHEGN---IAEMQTGEGKTLTATMPL--YLNALTGKGAYLITTNDYLAGRDYEEMKPLYEWLGLTTSLG 154
Cdd:smart00487 9 LRPYQKEAIEALLSGLrdvILAAPTGSGKTLAALLPAleALKRGKGGRVLVLVPTRELAEQWAEELKKLGPSLGLKVVGL 88
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 973245241 155 FVDipDYEYQKNEKAMLYKHDIVYTTNGRLgFDYLIDNladsieGKFLPKLNYGIIDEVDSII 217
Cdd:smart00487 89 YGG--DSKREQLRKLESGKTDILVTTPGRL-LDLLEND------KLSLSNVDLVILDEAHRLL 142
|
|
| DEXHc_archSki2 |
cd18028 |
DEXH-box helicase domain of archaeal Ski2-type helicase; Archaeal Ski2-type RNA helicases play ... |
78-216 |
4.22e-04 |
|
DEXH-box helicase domain of archaeal Ski2-type helicase; Archaeal Ski2-type RNA helicases play an important role in RNA degradation, processing and splicing pathways. They belong to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350786 [Multi-domain] Cd Length: 177 Bit Score: 41.94 E-value: 4.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 973245241 78 MYPKDVQVLGAIVLHEGN-IAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAGRDYEEMKPLYEW-LGLTTSLGF 155
Cdd:cd18028 2 LYPPQAEAVRAGLLKGENlLISIPTASGKTLIAEMAMVNTLLEGGKALYLVPLRALASEKYEEFKKLEEIgLKVGISTGD 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 973245241 156 VDIPDYEyqknekamLYKHDIVYTTNGRlgFDYLIDNLADsiegkFLPKLNYGIIDEVDSI 216
Cdd:cd18028 82 YDEDDEW--------LGDYDIIVATYEK--FDSLLRHSPS-----WLRDVGVVVVDEIHLI 127
|
|
| |
