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Conserved domains on  [gi|500262304|ref|WP_011913188|]
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MULTISPECIES: universal stress protein [Stutzerimonas]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK11175 super family cl28723
universal stress protein UspE; Provisional
 7-278 2.58e-60

universal stress protein UspE; Provisional


The actual alignment was detected with superfamily member PRK11175:

Pssm-ID: 236871 [Multi-domain]  Cd Length: 305  Bit Score: 193.56  E-value: 2.58e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304   7 ILVVIDPNQPQELALKRARLISTVSQSRL--------------HLLACDAKHD-HSG----HLANLRAQLE---SEGHQV 64
Cdd:PRK11175   6 ILVVIDPNQDDQPALRRAVYLAQRNGGKItaflpiydfsyemtTLLSPDEREAmRQGvisqRTAWIREQAKpylDAGIPI 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304  65 TTQQAWHESLHQTIIAAQQAEGCGLVVK---QHvpdNPLKRALLTPEDWKLLRYCPCPVLMVKtDNPW-TGGNILAAVDV 140
Cdd:PRK11175  86 EIKVVWHNRPFEAIIQEVIAGGHDLVVKmthQH---DKLESVIFTPTDWHLLRKCPCPVLMVK-DQDWpEGGKILVAVNV 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304 141 GNADLEHRTLHATIVNHGYEIAN-LADGKLHVISAHPSAMLSAA------DPAfQLKETIEARYREACKRFQEEFDIPDA 213
Cdd:PRK11175 162 ASEEPYHDALNEKLVEEAIDLAEqLNHAEVHLVNAYPVTPINIAielpefDPS-VYNDAIRGQHLLAMKALRQKFGIDEE 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 500262304 214 QLHVEEGPADALIPRVCHQLKAVVTVIGTVARTGFSGALMGNTAEVVLDTLESDVLVLKPDDVID 278
Cdd:PRK11175 241 QTHVEEGLPEEVIPDLAEHLDAELVILGTVGRTGLSAAFLGNTAEHVIDHLNCDLLAIKPDGYVS 305
 
Name Accession Description Interval E-value
PRK11175 PRK11175
universal stress protein UspE; Provisional
 7-278 2.58e-60

universal stress protein UspE; Provisional


Pssm-ID: 236871 [Multi-domain]  Cd Length: 305  Bit Score: 193.56  E-value: 2.58e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304   7 ILVVIDPNQPQELALKRARLISTVSQSRL--------------HLLACDAKHD-HSG----HLANLRAQLE---SEGHQV 64
Cdd:PRK11175   6 ILVVIDPNQDDQPALRRAVYLAQRNGGKItaflpiydfsyemtTLLSPDEREAmRQGvisqRTAWIREQAKpylDAGIPI 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304  65 TTQQAWHESLHQTIIAAQQAEGCGLVVK---QHvpdNPLKRALLTPEDWKLLRYCPCPVLMVKtDNPW-TGGNILAAVDV 140
Cdd:PRK11175  86 EIKVVWHNRPFEAIIQEVIAGGHDLVVKmthQH---DKLESVIFTPTDWHLLRKCPCPVLMVK-DQDWpEGGKILVAVNV 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304 141 GNADLEHRTLHATIVNHGYEIAN-LADGKLHVISAHPSAMLSAA------DPAfQLKETIEARYREACKRFQEEFDIPDA 213
Cdd:PRK11175 162 ASEEPYHDALNEKLVEEAIDLAEqLNHAEVHLVNAYPVTPINIAielpefDPS-VYNDAIRGQHLLAMKALRQKFGIDEE 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 500262304 214 QLHVEEGPADALIPRVCHQLKAVVTVIGTVARTGFSGALMGNTAEVVLDTLESDVLVLKPDDVID 278
Cdd:PRK11175 241 QTHVEEGLPEEVIPDLAEHLDAELVILGTVGRTGLSAAFLGNTAEHVIDHLNCDLLAIKPDGYVS 305
USP-E_repeat2 cd23660
Universal stress protein E, repeat 2; UspE is a tandem-type USP that consists of two USP ...
 131-273 2.66e-48

Universal stress protein E, repeat 2; UspE is a tandem-type USP that consists of two USP domains. The UspE expression levels of Escherichia coli become elevated in response to oxidative stress and DNA damaging agents, including exposure to mitomycin C, cadmium, and hydrogen peroxide. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity.


Pssm-ID: 467506  Cd Length: 148  Bit Score: 157.82  E-value: 2.66e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304 131 GGNILAAVDVGNADLEHRTLHATIVNHGYEIANLADGKLHVISAHPSAMLSAA-----DPAFQLKETIEARYREACKRFQ 205
Cdd:cd23660    1 GGRILVAVDPSNEEEYHEDLNLRLIELAYSLAAQLKAELHLVSAWPVTPENIAielpeFDPTEYVDAIRGRHLEAMKALR 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 500262304 206 EEFDIPDAQLHVEEGPADALIPRVCHQLKAVVTVIGTVARTGFSGALMGNTAEVVLDTLESDVLVLKP 273
Cdd:cd23660   81 QKFGIDEEQTHVLEGLPEEVIPDFAEELDADIVVLGTVARTGLSGALIGNTAEHVLDHLNCDLLALKP 148
UspA COG0589
Nucleotide-binding universal stress protein, UspA family [Signal transduction mechanisms];
133-270 7.24e-12

Nucleotide-binding universal stress protein, UspA family [Signal transduction mechanisms];


Pssm-ID: 440354  Cd Length: 136  Bit Score: 61.48  E-value: 7.24e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304 133 NILAAVDvGNADLEHrtlhatIVNHGYEIANLADGK---LHVISAHPSAMLSAADPAFQLKETIEARYREACKRFQEEfD 209
Cdd:COG0589    4 RILVPTD-GSEEAER------ALEYAAELAKALGAElhlLHVVDPPPSAAAGPEELEEELREEAEEALEEAAERLEEA-G 75

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 500262304 210 IpDAQLHVEEGPADALIPRVCHQLKAVVTVIGTVARTGFSGALMGNTAEVVLDTLESDVLV 270
Cdd:COG0589   76 V-EVETVVREGDPAEAILEAAEELDADLIVMGSRGRSGLRRLLLGSVAERVLRHAPCPVLV 135
Usp pfam00582
Universal stress protein family; The universal stress protein UspA is a small cytoplasmic ...
 134-272 1.62e-11

Universal stress protein family; The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.


Pssm-ID: 425765 [Multi-domain]  Cd Length: 137  Bit Score: 60.50  E-value: 1.62e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304  134 ILAAVDvgNADLEHRTLHativnHGYEIANLADGK---LHVISAHPSAMLSAADPAFQLKETI--EARYREACKRFQEEF 208
Cdd:pfam00582   1 ILVAVD--GSEESKRALE-----WAAELAKARGAElilLHVIDPPPSGAASLADESAEEEELEleLAEAEALAAAAAAEA 73

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 500262304  209 DIPDAQLHVEEGPADALIPRVCHQLKAVVTVIGTVARTGFSGALMGNTAEVVLDTLESDVLVLK 272
Cdd:pfam00582  74 GGVKVEVVVVVGDPAEEILEVAEEEDADLIVMGSRGRSGLSRLLLGSVAEYVLRHAPCPVLVVR 137
 
Name Accession Description Interval E-value
PRK11175 PRK11175
universal stress protein UspE; Provisional
 7-278 2.58e-60

universal stress protein UspE; Provisional


Pssm-ID: 236871 [Multi-domain]  Cd Length: 305  Bit Score: 193.56  E-value: 2.58e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304   7 ILVVIDPNQPQELALKRARLISTVSQSRL--------------HLLACDAKHD-HSG----HLANLRAQLE---SEGHQV 64
Cdd:PRK11175   6 ILVVIDPNQDDQPALRRAVYLAQRNGGKItaflpiydfsyemtTLLSPDEREAmRQGvisqRTAWIREQAKpylDAGIPI 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304  65 TTQQAWHESLHQTIIAAQQAEGCGLVVK---QHvpdNPLKRALLTPEDWKLLRYCPCPVLMVKtDNPW-TGGNILAAVDV 140
Cdd:PRK11175  86 EIKVVWHNRPFEAIIQEVIAGGHDLVVKmthQH---DKLESVIFTPTDWHLLRKCPCPVLMVK-DQDWpEGGKILVAVNV 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304 141 GNADLEHRTLHATIVNHGYEIAN-LADGKLHVISAHPSAMLSAA------DPAfQLKETIEARYREACKRFQEEFDIPDA 213
Cdd:PRK11175 162 ASEEPYHDALNEKLVEEAIDLAEqLNHAEVHLVNAYPVTPINIAielpefDPS-VYNDAIRGQHLLAMKALRQKFGIDEE 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 500262304 214 QLHVEEGPADALIPRVCHQLKAVVTVIGTVARTGFSGALMGNTAEVVLDTLESDVLVLKPDDVID 278
Cdd:PRK11175 241 QTHVEEGLPEEVIPDLAEHLDAELVILGTVGRTGLSAAFLGNTAEHVIDHLNCDLLAIKPDGYVS 305
USP-E_repeat2 cd23660
Universal stress protein E, repeat 2; UspE is a tandem-type USP that consists of two USP ...
 131-273 2.66e-48

Universal stress protein E, repeat 2; UspE is a tandem-type USP that consists of two USP domains. The UspE expression levels of Escherichia coli become elevated in response to oxidative stress and DNA damaging agents, including exposure to mitomycin C, cadmium, and hydrogen peroxide. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity.


Pssm-ID: 467506  Cd Length: 148  Bit Score: 157.82  E-value: 2.66e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304 131 GGNILAAVDVGNADLEHRTLHATIVNHGYEIANLADGKLHVISAHPSAMLSAA-----DPAFQLKETIEARYREACKRFQ 205
Cdd:cd23660    1 GGRILVAVDPSNEEEYHEDLNLRLIELAYSLAAQLKAELHLVSAWPVTPENIAielpeFDPTEYVDAIRGRHLEAMKALR 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 500262304 206 EEFDIPDAQLHVEEGPADALIPRVCHQLKAVVTVIGTVARTGFSGALMGNTAEVVLDTLESDVLVLKP 273
Cdd:cd23660   81 QKFGIDEEQTHVLEGLPEEVIPDFAEELDADIVVLGTVARTGLSGALIGNTAEHVLDHLNCDLLALKP 148
UspA COG0589
Nucleotide-binding universal stress protein, UspA family [Signal transduction mechanisms];
133-270 7.24e-12

Nucleotide-binding universal stress protein, UspA family [Signal transduction mechanisms];


Pssm-ID: 440354  Cd Length: 136  Bit Score: 61.48  E-value: 7.24e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304 133 NILAAVDvGNADLEHrtlhatIVNHGYEIANLADGK---LHVISAHPSAMLSAADPAFQLKETIEARYREACKRFQEEfD 209
Cdd:COG0589    4 RILVPTD-GSEEAER------ALEYAAELAKALGAElhlLHVVDPPPSAAAGPEELEEELREEAEEALEEAAERLEEA-G 75

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 500262304 210 IpDAQLHVEEGPADALIPRVCHQLKAVVTVIGTVARTGFSGALMGNTAEVVLDTLESDVLV 270
Cdd:COG0589   76 V-EVETVVREGDPAEAILEAAEELDADLIVMGSRGRSGLRRLLLGSVAERVLRHAPCPVLV 135
USP-E_repeat1 cd23943
Universal stress protein E, repeat 1; UspE is a tandem-type USP that consists of two USP ...
 7-124 1.34e-11

Universal stress protein E, repeat 1; UspE is a tandem-type USP that consists of two USP domains. The UspE expression levels of Escherichia coli become elevated in response to oxidative stress and DNA damaging agents, including exposure to mitomycin C, cadmium, and hydrogen peroxide. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity.


Pssm-ID: 467508  Cd Length: 143  Bit Score: 61.03  E-value: 1.34e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304   7 ILVVIDPNQPQELALKRARLISTVSQSRLH--------------LLACDAKHDH-----SGHLANLRAQLE---SEGHQV 64
Cdd:cd23943    4 MLVVIDPNQDDQPALRRAVYLVQRIGGKIKaflpiydlsyemttLLSPDERTAMrqgviSQRTAWIREQAKyylEAGIPI 83

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304  65 TTQQAWHESLHQTIIAAQQAEGCGLVVKQHVPDNPLKRALLTPEDWKLLRYCPCPVLMVK 124
Cdd:cd23943   84 EIKVVWHNRPFEAIIQEVIAGNHDLVLKMAHQHDRLESLIFTPTDWHLLRKCPSPVWMVK 143
Usp pfam00582
Universal stress protein family; The universal stress protein UspA is a small cytoplasmic ...
 134-272 1.62e-11

Universal stress protein family; The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.


Pssm-ID: 425765 [Multi-domain]  Cd Length: 137  Bit Score: 60.50  E-value: 1.62e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304  134 ILAAVDvgNADLEHRTLHativnHGYEIANLADGK---LHVISAHPSAMLSAADPAFQLKETI--EARYREACKRFQEEF 208
Cdd:pfam00582   1 ILVAVD--GSEESKRALE-----WAAELAKARGAElilLHVIDPPPSGAASLADESAEEEELEleLAEAEALAAAAAAEA 73

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 500262304  209 DIPDAQLHVEEGPADALIPRVCHQLKAVVTVIGTVARTGFSGALMGNTAEVVLDTLESDVLVLK 272
Cdd:pfam00582  74 GGVKVEVVVVVGDPAEEILEVAEEEDADLIVMGSRGRSGLSRLLLGSVAEYVLRHAPCPVLVVR 137
UspA COG0589
Nucleotide-binding universal stress protein, UspA family [Signal transduction mechanisms];
4-123 1.88e-10

Nucleotide-binding universal stress protein, UspA family [Signal transduction mechanisms];


Pssm-ID: 440354  Cd Length: 136  Bit Score: 57.62  E-value: 1.88e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304   4 IRCILVVIDPNQPQELALKRARLISTVSQSRLHLLAC----------------DAKHDHSGHLANLRAQLESEGHQVTTQ 67
Cdd:COG0589    2 YKRILVPTDGSEEAERALEYAAELAKALGAELHLLHVvdpppsaaagpeeleeELREEAEEALEEAAERLEEAGVEVETV 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 500262304  68 QAwHESLHQTIIAAQQAEGCGLVVKQHVPDNPLKRALLTPEDWKLLRYCPCPVLMV 123
Cdd:COG0589   82 VR-EGDPAEAILEAAEELDADLIVMGSRGRSGLRRLLLGSVAERVLRHAPCPVLVV 136
USP-like cd00293
universal stress protein (USP) and similar proteins; The universal stress protein (USP) is a ...
 7-123 5.85e-10

universal stress protein (USP) and similar proteins; The universal stress protein (USP) is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. USP enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, although USP lacks ATP-binding activity.


Pssm-ID: 467483 [Multi-domain]  Cd Length: 135  Bit Score: 56.20  E-value: 5.85e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304   7 ILVVIDPNQPQELALKRARLISTVSQSRLHLLAC------------------DAKHDHSGHLANLRAQLESEGHQVTTQQ 68
Cdd:cd00293    2 ILVAVDGSEESERALEWALELAKRPGAELTLLHVvdpppssslsggleeladELKEEAEELLEEAKKLAEEAGVEVETIV 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 500262304  69 AWHESlHQTIIAAQQAEGCGLVVKQHVPDNPLKRALLTPEDWKLLRYCPCPVLMV 123
Cdd:cd00293   82 VEGDP-AEAILEEAKELGADLIVMGSRGRSGLKRLLLGSVSEYVLRHAPCPVLVV 135
USP-A-like cd23657
universal stress protein A and similar proteins; The universal stress protein UspA is a small ...
 133-273 1.81e-08

universal stress protein A and similar proteins; The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced several-fold when cellular viability is challenged with heat shock, nutrient starvation, stress agents which arrest cell growth, or DNA-damaging agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, suggesting that it asserts a general "stress endurance" activity. In general, these proteins form dimers and have domains for nucleotide binding activity. The crystal structure of Haemophilus influenzae UspA reveals an asymmetric dimer with a tertiary alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, but unlike MJ0577, it lacks ATP-binding activity.


Pssm-ID: 467504  Cd Length: 138  Bit Score: 52.31  E-value: 1.81e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304 133 NILAAVDVGNADlehrtlhATIVNHGYEIANLADGKL---HVISAHPSAMLSAADPAFQ-LKETIEARYREACKRFQEEF 208
Cdd:cd23657    3 HILVAVDLSPES-------QSLVDKAVEIARENDAKLsliHVDEDISEYYTGLIDVDIAaLQDLESTMLEEALKNLSELA 75

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 500262304 209 DIPDAQLHVEEGPADALIPRVCHQLKAVVTVIGTVARTGFSgaLMGNTAEVVLDTLESDVLVLKP 273
Cdd:cd23657   76 GYPVDHTFIGYGDLKEEILEVAKKHNVDLIVCGHHGDFGLS--LLGSSARAVLNSAPCDVLIVPL 138
USP-like cd00293
universal stress protein (USP) and similar proteins; The universal stress protein (USP) is a ...
 133-270 2.93e-06

universal stress protein (USP) and similar proteins; The universal stress protein (USP) is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. USP enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, although USP lacks ATP-binding activity.


Pssm-ID: 467483 [Multi-domain]  Cd Length: 135  Bit Score: 45.80  E-value: 2.93e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304 133 NILAAVDvGNADLEHrtlhatIVNHGYEIANLADGKLHVISAHPSAMLSAADPAF-QLKETIEARYREACKRFQEEFDIP 211
Cdd:cd00293    1 KILVAVD-GSEESER------ALEWALELAKRPGAELTLLHVVDPPPSSSLSGGLeELADELKEEAEELLEEAKKLAEEA 73

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 500262304 212 --DAQLHVEEG-PADALIpRVCHQLKAVVTVIGTVARTGFSGALMGNTAEVVLDTLESDVLV 270
Cdd:cd00293   74 gvEVETIVVEGdPAEAIL-EEAKELGADLIVMGSRGRSGLKRLLLGSVSEYVLRHAPCPVLV 134
Usp pfam00582
Universal stress protein family; The universal stress protein UspA is a small cytoplasmic ...
 7-124 3.70e-06

Universal stress protein family; The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.


Pssm-ID: 425765 [Multi-domain]  Cd Length: 137  Bit Score: 45.48  E-value: 3.70e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304    7 ILVVIDPNQPQELALKRARLISTVSQSRLHLL-ACDAKHDHSGHLANLRAQLESEGHQVTTQQAWHESLHQ--------- 76
Cdd:pfam00582   1 ILVAVDGSEESKRALEWAAELAKARGAELILLhVIDPPPSGAASLADESAEEEELELELAEAEALAAAAAAeaggvkvev 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 500262304   77 ---------TIIAAQQAEGCGLVVKQHVPDNPLKRALLTPEDWKLLRYCPCPVLMVK 124
Cdd:pfam00582  81 vvvvgdpaeEILEVAEEEDADLIVMGSRGRSGLSRLLLGSVAEYVLRHAPCPVLVVR 137
PRK15005 PRK15005
universal stress protein UspF;
134-272 1.01e-04

universal stress protein UspF;


Pssm-ID: 184967 [Multi-domain]  Cd Length: 144  Bit Score: 41.71  E-value: 1.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304 134 ILAAVDVGNADLEHRtlhatIVNHGYEIANLADGKLHVISAHPS----AML----SAADPAF-QLKETIEARYREACKRF 204
Cdd:PRK15005   5 ILVPIDISDSELTQR-----VISHVEAEAKIDDAEVHFLTVIPSlpyyASLglaySAELPAMdDLKAEAKSQLEEIIKKF 79

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304 205 qeefDIPD--AQLHVEEGPADALIPRVCHQLKAVVTVIGTvARTGFSGALMGNTAEVVLDTLESDVLVLK 272
Cdd:PRK15005  80 ----KLPTdrVHVHVEEGSPKDRILELAKKIPADMIIIAS-HRPDITTYLLGSNAAAVVRHAECSVLVVR 144
USP_At3g01520-like cd23659
universal stress protein At3g01520 and similar proteins; This subfamily includes plant and ...
 169-272 6.27e-03

universal stress protein At3g01520 and similar proteins; This subfamily includes plant and fungal proteins of unknown function, including Arabidopsis thaliana At3g01520. A. thaliana contains 44 USP domain-containing proteins; the USP domain is found either in a small protein with unknown physiological function or as an N-terminal portion of a multi-domain protein, usually a protein kinase. The gene At3g01520 of Arabidopsis thaliana encodes a 175-residue universal stress protein (USP)-like protein which is widely found in the genomes of bacteria, as well as fungi, protozoa, and plants. The bound AMP and conservation of residues in the ATP-binding loop suggest that the protein At3g01520 belongs to the ATP-binding USP subfamily. Universal stress proteins (USPs) are small cytoplasmic bacterial proteins whose expression is enhanced when the cell is exposed to stress agents. USP enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity.


Pssm-ID: 467505  Cd Length: 143  Bit Score: 36.44  E-value: 6.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 500262304 169 LHVISAHPSAMLSAaDPAFQLKETIEARYREACKRFQEEFDIPDAQ-------LHVEEGPADALIPRVCHQLKAVVTVIG 241
Cdd:cd23659   34 LHVIEPPSLPAASL-GSGSEEWEALEEEAREKAEKLLEKYEKKLKEekgikvkVEVVAGDPGEVICKAAEELKADLIVMG 112

                         90       100       110
                 ....*....|....*....|....*....|.
gi 500262304 242 TVARTGFSGALMGNTAEVVLDTLESDVLVLK 272
Cdd:cd23659  113 SRGLGALKRTLLGSVSDYVVHHSPCPVLVVR 143
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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