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Conserved domains on  [gi|499768298|ref|WP_011449032|]
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NAD(P)/FAD-dependent oxidoreductase [Methanospirillum hungatei]

Protein Classification

phytoene desaturase family protein( domain architecture ID 11440907)

phytoene desaturase family protein is an NAD(P)/FAD-dependent oxidoreductase that catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant; similar to phytoene desaturase, which converts phytoene into 3,4-didehydrolycopene via several intermediates by introducing up to five double bonds into phytoene

CATH:  3.50.50.60
EC:  1.-.-.-
Gene Ontology:  GO:0016491|GO:0009055|GO:0016117|GO:0016116
SCOP:  4000128|3000055

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 1-481 1.68e-106

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 325.65  E-value: 1.68e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298   1 MAPSVLIIGGGMAGLSAGCFARMNGFETEILEMHTIPGGLCTAWTRKGYTFDLCIHWLCgskPGTPLYQVYDKLGLMEGR 80
Cdd:COG1233    2 MMYDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTPGGRARTFERPGFRFDVGPSVLT---MPGVLERLFRELGLEDYL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  81 RFHHTDSWTSVRDEHGNEITIYTDPDRLYDELIRISPEDTPFISRLCKDIKKLSR--METLVD---MTILDIIRYIPYFS 155
Cdd:COG1233   79 ELVPLDPAYRVPFPDGRALDLPRDLERTAAELERLFPGDAEAYRRFLAELRRLYDalLEDLLYrplLSLRDLLRPLALAR 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 156 LMKRYKPTVHDILSE-VKSPVLRNLLTAGFGWEGQSLFFP--LMGLAMQGAKNAG--YPIGGSLPCAKAIEKRYLDLGGV 230
Cdd:COG1233  159 LLRLLLRSLRDLLRRyFKDPRLRALLAGQALYLGLSPDRTpaLYALIAYLEYAGGvwYPKGGMGALADALARLAEELGGE 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 231 IRYKSKVTAIITEKNRAKGVRLADGTERYADYVISCADGHTTIFEWLQGAYCDDTIRGYYQNLKPFPPIVFISFGLSTDL 310
Cdd:COG1233  239 IRTGAEVERILVEGGRATGVRLADGEEIRADAVVSNADPAHTYLRLLGEEALPARYRRRLERFRYSPSAFKLYLGLDGPL 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 311 SHIPKdLTILFDNPVEIA-------GVKQD-TISFRNH-VHDPTLYPPGKGVITTWITADYSYWDRLQyhseaylAEKDD 381
Cdd:COG1233  319 PGLAH-HTIHLSEDYEAAfddifrgRLPEDpSLYVSIPsLTDPSLAPEGKHTLWVLVPVPYGLEDAWD-------ELKEE 390

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 382 VGRKVLALLCQQYPDLSERCEVMDVATPMTFVRYTGNWRGSYEGWQVTPD-SFFLDLPQILPGLSGFSMAGQWVVTGGGI 460
Cdd:COG1233  391 YAERILARLERYAPGLRDRIVAREVLTPLDFERYLNLVGGAIYGGAHTLDqSAFFRPSNYRTPIPGLYLVGASTHPGGGV 470

                        490       500
                 ....*....|....*....|.
gi 499768298 461 PGAVLSGRKAVKQMCSDFGKK 481
Cdd:COG1233  471 PGVLISGRLAARRILKDLKRA 491
 
Name Accession Description Interval E-value
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 1-481 1.68e-106

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 325.65  E-value: 1.68e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298   1 MAPSVLIIGGGMAGLSAGCFARMNGFETEILEMHTIPGGLCTAWTRKGYTFDLCIHWLCgskPGTPLYQVYDKLGLMEGR 80
Cdd:COG1233    2 MMYDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTPGGRARTFERPGFRFDVGPSVLT---MPGVLERLFRELGLEDYL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  81 RFHHTDSWTSVRDEHGNEITIYTDPDRLYDELIRISPEDTPFISRLCKDIKKLSR--METLVD---MTILDIIRYIPYFS 155
Cdd:COG1233   79 ELVPLDPAYRVPFPDGRALDLPRDLERTAAELERLFPGDAEAYRRFLAELRRLYDalLEDLLYrplLSLRDLLRPLALAR 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 156 LMKRYKPTVHDILSE-VKSPVLRNLLTAGFGWEGQSLFFP--LMGLAMQGAKNAG--YPIGGSLPCAKAIEKRYLDLGGV 230
Cdd:COG1233  159 LLRLLLRSLRDLLRRyFKDPRLRALLAGQALYLGLSPDRTpaLYALIAYLEYAGGvwYPKGGMGALADALARLAEELGGE 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 231 IRYKSKVTAIITEKNRAKGVRLADGTERYADYVISCADGHTTIFEWLQGAYCDDTIRGYYQNLKPFPPIVFISFGLSTDL 310
Cdd:COG1233  239 IRTGAEVERILVEGGRATGVRLADGEEIRADAVVSNADPAHTYLRLLGEEALPARYRRRLERFRYSPSAFKLYLGLDGPL 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 311 SHIPKdLTILFDNPVEIA-------GVKQD-TISFRNH-VHDPTLYPPGKGVITTWITADYSYWDRLQyhseaylAEKDD 381
Cdd:COG1233  319 PGLAH-HTIHLSEDYEAAfddifrgRLPEDpSLYVSIPsLTDPSLAPEGKHTLWVLVPVPYGLEDAWD-------ELKEE 390

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 382 VGRKVLALLCQQYPDLSERCEVMDVATPMTFVRYTGNWRGSYEGWQVTPD-SFFLDLPQILPGLSGFSMAGQWVVTGGGI 460
Cdd:COG1233  391 YAERILARLERYAPGLRDRIVAREVLTPLDFERYLNLVGGAIYGGAHTLDqSAFFRPSNYRTPIPGLYLVGASTHPGGGV 470

                        490       500
                 ....*....|....*....|.
gi 499768298 461 PGAVLSGRKAVKQMCSDFGKK 481
Cdd:COG1233  471 PGVLISGRLAARRILKDLKRA 491
crtI_fam TIGR02734
phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two ...
 5-481 1.96e-23

phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 274273 [Multi-domain]  Cd Length: 495  Bit Score: 103.13  E-value: 1.96e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298    5 VLIIGGGMAGLSAGCFARMNGFETEILEMHTIPGGLCTAWTRKGYTFDLCIHW------------LCGSK--------PG 64
Cdd:TIGR02734   1 AVVIGAGFGGLALAIRLAAAGIPVTVVEQRDKPGGRAGVLEDDGFRFDTGPTVitmpealeelfaLAGRDladyvelvPL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298   65 TPLYQVYdklglmegrrfhhtdsWtsvrdEHGNEITIYTDPDRLYDELIRISPEDTPFISRLCKDIKKLSR--METLVDM 142
Cdd:TIGR02734  81 DPFYRLC----------------W-----EDGSQLDVDNDQEELEAQIARFNPGDVAGYRRFLDYAERVYRegYRKLGYV 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  143 TILDiiryipYFSLMKRYKP---------TVHD-ILSEVKSPVLRNLLTagFgwegQSLFF---PLMGLAM--------- 200
Cdd:TIGR02734 140 PFLS------PRDLLRADAPqllallawrSLYSkVARFFSDERLRQAFS--F----HALFLggnPFRTPSIyalisaler 207

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  201 -QGAKnagYPIGGSLPCAKAIEKRYLDLGGVIRYKSKVTAIITEKNRAKGVRLADGTERYADYVISCADGHTTIFEWL-- 277
Cdd:TIGR02734 208 eWGVW---FPRGGTGALVAAMAKLAEDLGGELRLNAEVIRIETEGGRATAVHLADGERLDADAVVSNADLHHTYRRLLpn 284

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  278 --QGAYCDDtirgYYQNLKPFPPIVFISFGLSTDLSHIPkDL---TILF-----DNPVEI---AGVKQDTISF--RNHVH 342
Cdd:TIGR02734 285 hpRRRYPAA----RLSRKRPSPSLFVLYFGLLGVDGHWP-QLahhTLCFgprykELFDEIfrkGRLAEDPSLYlhRPTVT 359

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  343 DPTLYPPGKGviTTWITADYSywdrlqyHSEAYLAEKDDVG----RKVLALLCQQY-PDLSERCEVMDVATPMTFVRYTG 417
Cdd:TIGR02734 360 DPSLAPPGCE--SLYVLAPVP-------HLGTADVDWSVEGpryrDRILAYLEERAiPGLRDRIVVERTFTPADFRDRYN 430

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 499768298  418 NWRGSyeGWQVTPdsfflDLPQILP--------GLSGFSMAGQWVVTGGGIPGAVLSGRKAVKQMCSDFGKK 481
Cdd:TIGR02734 431 AWLGS--AFSLEH-----TLTQSAWfrphnrdrKIDNLYLVGAGTHPGAGVPGVLGSAKATAKLMLGDLAPG 495
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 12-474 6.17e-22

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 97.95  E-value: 6.17e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298   12 MAGLSAgcfAR---MNGFETEILEMHTIPGGLCTAWTRKGYTFDLCIHWLCGSKPgtPLYQVYDKLGLMEGRRFHhtdsw 88
Cdd:pfam01593   1 LAGLAA---ARellRAGHDVTVLEARDRVGGRIRTVRDDGFLIELGAMWFHGAQP--PLLALLKELGLEDRLVLP----- 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298   89 tsvrdEHGNEITIYTDPDRLYDELIR---ISPEDTPFISRLCKDIKKLSRMETL-----VDMTILDIIRYIPYFSLMKRY 160
Cdd:pfam01593  71 -----DPAPFYTVLFAGGRRYPGDFRrvpAGWEGLLEFGRLLSIPEKLRLGLAAlasdaLDEFDLDDFSLAESLLFLGRR 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  161 KPTVHDILSEVKSPVLRNLLTAGFG-------WEGQSLFFPLMGLAMQGAKNAGYPIGGSLPCAKAIEKRYLdlGGVIRY 233
Cdd:pfam01593 146 GPGDVEVWDRLIDPELFAALPFASGafagdpsELSAGLALPLLWALLGEGGSLLLPRGGLGALPDALAAQLL--GGDVRL 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  234 KSKVTAIITEKNRAKgVRLADGTERYADYVISCADGHT--------TIFEWLQGAycddtIRGYyqnlkPFPPI--VFIS 303
Cdd:pfam01593 224 NTRVRSIDREGDGVT-VTLTDGEVIEADAVIVTVPLGVlkrilftpPLPPEKARA-----IRNL-----GYGPVnkVHLE 292

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  304 F--------GLSTDLSHIPKDLTILFdnpveiagvkqdtISFrnhvHDPTLYPPGKG-VITTWITADYSYWDRLQYHsea 374
Cdd:pfam01593 293 FdrkfwpdlGLLGLLSELLTGLGTAF-------------SWL----TFPNRAPPGKGlLLLVYVGPGDRARELEGLS--- 352

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  375 ylaeKDDVGRKVLALLCQQYPDL---SERCEVMDVATpmtfVRYTgnwRGSYEGWQVTPDSFFLDLPQiLPGLSGFSMAG 451
Cdd:pfam01593 353 ----DEELLQAVLRDLRKLFGEEapePLRVLVSDWHT----DPWP---RGSYSLPQYGPGHDDYRPLA-RTPDPGLFFAG 420

                         490       500
                  ....*....|....*....|....*
gi 499768298  452 QWVVTG--GGIPGAVLSGRKAVKQM 474
Cdd:pfam01593 421 EHTSTGypGTVEGAIESGRRAARAV 445
PRK07233 PRK07233
hypothetical protein; Provisional
 5-265 3.04e-08

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 55.66  E-value: 3.04e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298   5 VLIIGGGMAGLSAGCFARMNGFETEILEMHTIPGGLCTAWTRKGYTFDLCIHWLCGSKpgTPLYQVYDKLGLMEGRRFHH 84
Cdd:PRK07233   2 IAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGLAASFEFGGLPIERFYHHIFKSD--EALLELLDELGLEDKLRWRE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  85 TdswtsvrdehgneITIYTDPDRLYD-----ELIRISPedTPFISR-----LCKDIKKLSRMETLVDMTILDIIRyipyf 154
Cdd:PRK07233  80 T-------------KTGYYVDGKLYPlgtplELLRFPH--LSLIDKfrlglLTLLARRIKDWRALDKVPAEEWLR----- 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 155 slmKRYKPTVHDILsevkspvLRNLLTAGFG---------W----------EGQSLFFPLMGlamqgaknagYPIGGSLP 215
Cdd:PRK07233 140 ---RWSGEGVYEVF-------WEPLLESKFGdyaddvsaaWlwsrikrrgnRRYSLFGEKLG----------YLEGGFAT 199

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 499768298 216 CAKAIEKRYLDLGGVIRYKSKVTAIITEKNRAKGVRLADGTERYaDYVIS 265
Cdd:PRK07233 200 LIDALAEAIEARGGEIRLGTPVTSVVIDGGGVTGVEVDGEEEDF-DAVIS 248
 
Name Accession Description Interval E-value
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 1-481 1.68e-106

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 325.65  E-value: 1.68e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298   1 MAPSVLIIGGGMAGLSAGCFARMNGFETEILEMHTIPGGLCTAWTRKGYTFDLCIHWLCgskPGTPLYQVYDKLGLMEGR 80
Cdd:COG1233    2 MMYDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTPGGRARTFERPGFRFDVGPSVLT---MPGVLERLFRELGLEDYL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  81 RFHHTDSWTSVRDEHGNEITIYTDPDRLYDELIRISPEDTPFISRLCKDIKKLSR--METLVD---MTILDIIRYIPYFS 155
Cdd:COG1233   79 ELVPLDPAYRVPFPDGRALDLPRDLERTAAELERLFPGDAEAYRRFLAELRRLYDalLEDLLYrplLSLRDLLRPLALAR 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 156 LMKRYKPTVHDILSE-VKSPVLRNLLTAGFGWEGQSLFFP--LMGLAMQGAKNAG--YPIGGSLPCAKAIEKRYLDLGGV 230
Cdd:COG1233  159 LLRLLLRSLRDLLRRyFKDPRLRALLAGQALYLGLSPDRTpaLYALIAYLEYAGGvwYPKGGMGALADALARLAEELGGE 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 231 IRYKSKVTAIITEKNRAKGVRLADGTERYADYVISCADGHTTIFEWLQGAYCDDTIRGYYQNLKPFPPIVFISFGLSTDL 310
Cdd:COG1233  239 IRTGAEVERILVEGGRATGVRLADGEEIRADAVVSNADPAHTYLRLLGEEALPARYRRRLERFRYSPSAFKLYLGLDGPL 318

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 311 SHIPKdLTILFDNPVEIA-------GVKQD-TISFRNH-VHDPTLYPPGKGVITTWITADYSYWDRLQyhseaylAEKDD 381
Cdd:COG1233  319 PGLAH-HTIHLSEDYEAAfddifrgRLPEDpSLYVSIPsLTDPSLAPEGKHTLWVLVPVPYGLEDAWD-------ELKEE 390

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 382 VGRKVLALLCQQYPDLSERCEVMDVATPMTFVRYTGNWRGSYEGWQVTPD-SFFLDLPQILPGLSGFSMAGQWVVTGGGI 460
Cdd:COG1233  391 YAERILARLERYAPGLRDRIVAREVLTPLDFERYLNLVGGAIYGGAHTLDqSAFFRPSNYRTPIPGLYLVGASTHPGGGV 470

                        490       500
                 ....*....|....*....|.
gi 499768298 461 PGAVLSGRKAVKQMCSDFGKK 481
Cdd:COG1233  471 PGVLISGRLAARRILKDLKRA 491
crtI_fam TIGR02734
phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two ...
 5-481 1.96e-23

phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 274273 [Multi-domain]  Cd Length: 495  Bit Score: 103.13  E-value: 1.96e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298    5 VLIIGGGMAGLSAGCFARMNGFETEILEMHTIPGGLCTAWTRKGYTFDLCIHW------------LCGSK--------PG 64
Cdd:TIGR02734   1 AVVIGAGFGGLALAIRLAAAGIPVTVVEQRDKPGGRAGVLEDDGFRFDTGPTVitmpealeelfaLAGRDladyvelvPL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298   65 TPLYQVYdklglmegrrfhhtdsWtsvrdEHGNEITIYTDPDRLYDELIRISPEDTPFISRLCKDIKKLSR--METLVDM 142
Cdd:TIGR02734  81 DPFYRLC----------------W-----EDGSQLDVDNDQEELEAQIARFNPGDVAGYRRFLDYAERVYRegYRKLGYV 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  143 TILDiiryipYFSLMKRYKP---------TVHD-ILSEVKSPVLRNLLTagFgwegQSLFF---PLMGLAM--------- 200
Cdd:TIGR02734 140 PFLS------PRDLLRADAPqllallawrSLYSkVARFFSDERLRQAFS--F----HALFLggnPFRTPSIyalisaler 207

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  201 -QGAKnagYPIGGSLPCAKAIEKRYLDLGGVIRYKSKVTAIITEKNRAKGVRLADGTERYADYVISCADGHTTIFEWL-- 277
Cdd:TIGR02734 208 eWGVW---FPRGGTGALVAAMAKLAEDLGGELRLNAEVIRIETEGGRATAVHLADGERLDADAVVSNADLHHTYRRLLpn 284

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  278 --QGAYCDDtirgYYQNLKPFPPIVFISFGLSTDLSHIPkDL---TILF-----DNPVEI---AGVKQDTISF--RNHVH 342
Cdd:TIGR02734 285 hpRRRYPAA----RLSRKRPSPSLFVLYFGLLGVDGHWP-QLahhTLCFgprykELFDEIfrkGRLAEDPSLYlhRPTVT 359

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  343 DPTLYPPGKGviTTWITADYSywdrlqyHSEAYLAEKDDVG----RKVLALLCQQY-PDLSERCEVMDVATPMTFVRYTG 417
Cdd:TIGR02734 360 DPSLAPPGCE--SLYVLAPVP-------HLGTADVDWSVEGpryrDRILAYLEERAiPGLRDRIVVERTFTPADFRDRYN 430

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 499768298  418 NWRGSyeGWQVTPdsfflDLPQILP--------GLSGFSMAGQWVVTGGGIPGAVLSGRKAVKQMCSDFGKK 481
Cdd:TIGR02734 431 AWLGS--AFSLEH-----TLTQSAWfrphnrdrKIDNLYLVGAGTHPGAGVPGVLGSAKATAKLMLGDLAPG 495
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 12-474 6.17e-22

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 97.95  E-value: 6.17e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298   12 MAGLSAgcfAR---MNGFETEILEMHTIPGGLCTAWTRKGYTFDLCIHWLCGSKPgtPLYQVYDKLGLMEGRRFHhtdsw 88
Cdd:pfam01593   1 LAGLAA---ARellRAGHDVTVLEARDRVGGRIRTVRDDGFLIELGAMWFHGAQP--PLLALLKELGLEDRLVLP----- 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298   89 tsvrdEHGNEITIYTDPDRLYDELIR---ISPEDTPFISRLCKDIKKLSRMETL-----VDMTILDIIRYIPYFSLMKRY 160
Cdd:pfam01593  71 -----DPAPFYTVLFAGGRRYPGDFRrvpAGWEGLLEFGRLLSIPEKLRLGLAAlasdaLDEFDLDDFSLAESLLFLGRR 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  161 KPTVHDILSEVKSPVLRNLLTAGFG-------WEGQSLFFPLMGLAMQGAKNAGYPIGGSLPCAKAIEKRYLdlGGVIRY 233
Cdd:pfam01593 146 GPGDVEVWDRLIDPELFAALPFASGafagdpsELSAGLALPLLWALLGEGGSLLLPRGGLGALPDALAAQLL--GGDVRL 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  234 KSKVTAIITEKNRAKgVRLADGTERYADYVISCADGHT--------TIFEWLQGAycddtIRGYyqnlkPFPPI--VFIS 303
Cdd:pfam01593 224 NTRVRSIDREGDGVT-VTLTDGEVIEADAVIVTVPLGVlkrilftpPLPPEKARA-----IRNL-----GYGPVnkVHLE 292

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  304 F--------GLSTDLSHIPKDLTILFdnpveiagvkqdtISFrnhvHDPTLYPPGKG-VITTWITADYSYWDRLQYHsea 374
Cdd:pfam01593 293 FdrkfwpdlGLLGLLSELLTGLGTAF-------------SWL----TFPNRAPPGKGlLLLVYVGPGDRARELEGLS--- 352

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  375 ylaeKDDVGRKVLALLCQQYPDL---SERCEVMDVATpmtfVRYTgnwRGSYEGWQVTPDSFFLDLPQiLPGLSGFSMAG 451
Cdd:pfam01593 353 ----DEELLQAVLRDLRKLFGEEapePLRVLVSDWHT----DPWP---RGSYSLPQYGPGHDDYRPLA-RTPDPGLFFAG 420

                         490       500
                  ....*....|....*....|....*
gi 499768298  452 QWVVTG--GGIPGAVLSGRKAVKQM 474
Cdd:pfam01593 421 EHTSTGypGTVEGAIESGRRAARAV 445
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
7-74 1.11e-15

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 71.41  E-value: 1.11e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499768298    7 IIGGGMAGLSAGCFARMNGFETEILEMHTIPGGLCTAWTRKGYTFDLCIHWLCGSKPgTPLYQVYDKL 74
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNAYSYRVPGYVFDYGAHIFHGSDE-PNVRDLLDEL 67
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 1-479 7.39e-13

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 70.27  E-value: 7.39e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298   1 MAPSVLIIGGGMAGLSAGCFARMNGFETEILEMHTIPGGLCTAWTRK--GYTFDLCIHWLcgskPG--TPLYQVYDKLGL 76
Cdd:COG3349    2 MPPRVVVVGGGLAGLAAAVELAEAGFRVTLLEARPRLGGRARSFPDPdtGLPIDNGQHVL----LGcyRNTLDLLRRIGA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  77 MEGRRFHHTdswTSVRDEHGNEITIYT----DPDRLYDELIR---ISPEDTPFISRLCKDIkKLSRMETLVDMTILDiir 149
Cdd:COG3349   78 ADNLVGPEP---LQFPLPGGRRWTLRAprlpAPLHLLRALLRapgLSLADRLALLRLLTAC-RERRWRELDDISVAD--- 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 150 yipyfsLMKRYKptvhdilsevKSPVLRNLLtagfgWEG--QS-LFFP-------LMG-------LAMQGAKNAGYPIGG 212
Cdd:COG3349  151 ------WLRRHG----------QSPRLIRRL-----WEPllLAaLNTPpeqasarLALtvlretlLAGPAASDLLVPRGP 209

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 213 -----SLPCAKAIEKRyldlGGVIRYKSKVTAIITEKNRAKGVRLADGTERYADYVIsCADGHTTIFEWLQGAYCDDTIR 287
Cdd:COG3349  210 lselfVDPALAYLEAR----GGEVRLGTRVRALEFDGGRVTGLVLADGETVPADAVV-LAVPPEVAARLLPELARLPELG 284

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 288 gyyqNLKPFP--PIVFISFGLSTDLSHIPKDLTILFDNPVEiagvkqdtisfrnhvhdptlyppgkgvittWITADYSYW 365
Cdd:COG3349  285 ----LLAPLEysPIVNVHLWLDRPVTLGPPPFAGLVGSTSQ------------------------------WVFDRGAGD 330

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 366 ----DRLQ---YHSEAYLAE-KDDVGRKVLALLCQQYPDLSErcevmdvATPM----------TFVrytgnwrgsyegwq 427
Cdd:COG3349  331 ggqgGVLSvviSAADRLLDLsREELAAEVWAELAALLPAARE-------ALPVwsrvvrekraTFA-------------- 389

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....
gi 499768298 428 VTPDSFFLdLPQILPGLSGFSMAGQWVVTGGG--IPGAVLSGRKAVKQMCSDFG 479
Cdd:COG3349  390 ATPGSDRL-RPGARTPIPNLFLAGDWTATGLPatMEGAVRSGRRAANAILARLG 442
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 3-473 2.28e-12

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 68.71  E-value: 2.28e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298   3 PSVLIIGGGMAGLSAGCFARMNGFETEILEMHTIPGGLCTAWTRKGYTFDLCIHWLCGSKPgtPLYQVYDKLGLmeGRRF 82
Cdd:COG1232    2 KRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVGGLIRTVEVDGFRIDRGPHSFLTRDP--EVLELLRELGL--GDEL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  83 HHTDSWTSVrdehgneitIYTDpDRLYD------ELIR---ISPEDTpfiSRLCKDIkKLSRMETLVDMTILDIIRyipy 153
Cdd:COG1232   78 VWPNTRKSY---------IYYG-GKLHPlpqgplALLRsplLSLAGK---LRALLEL-LAPRRPPGEDESLAEFVR---- 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 154 fslmKRYKPTVHDILSEvksPVLR-------NLLTAGFGW--------EGQSLFFPLMGLAMQGAKNA--GYPIGG--SL 214
Cdd:COG1232  140 ----RRFGREVYERLVE---PLLEgvyagdpDELSADWAFprlkrlelEHGSLIKGALALRKGAKAGEvfGYLRGGlgTL 212

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 215 P--CAKAIEKryldlgGVIRYKSKVTAIITEKNRaKGVRLADGTERYADYVISCADGHTTIfEWLQGAycDDTIRGYYQN 292
Cdd:COG1232  213 VeaLAEALEA------GEIRLGTRVTAIEREGGG-WRVTTSDGETIEADAVVSATPAPALA-RLLAPL--PPEVAAALAG 282

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 293 LkPFPPIVFISFGLstDLSHIPKDLTILF----DNPVEIAGVkqdtISFRNHVhdPTLYPPGKgvitTWITADYSywdrl 368
Cdd:COG1232  283 I-PYASVAVVALGF--DRPDLPPPDGFGWlvprDEGVPILAV----TFSSNKW--PHRAPDGK----VLLRLEVG----- 344

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 369 QYHSEAYLAEKDD-VGRKVLAllcqqypDLSercEVMDVATPMTFVRYTGnWRGSYEgwQVTPDsfFLD-LPQI---LPG 443
Cdd:COG1232  345 GAGDPELWQLSDEeLVALALA-------DLR---KLLGIDAEPVDTRVVR-WPKAYP--QYTVG--HLErVAAIreaLAA 409

                        490       500       510
                 ....*....|....*....|....*....|
gi 499768298 444 LSGFSMAGQWvVTGGGIPGAVLSGRKAVKQ 473
Cdd:COG1232  410 LPGLYLAGRA-YDGVGLPDCIRSGREAAER 438
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
3-267 5.41e-10

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 61.09  E-value: 5.41e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298   3 PSVLIIGGGMAGLSAgcfARM---NGFETEILEMHTIPGGLCtaWTR----KGYTFDLCIHWLCGSKP---------GTP 66
Cdd:COG1231    8 KDVVIVGAGLAGLAA---ARElrkAGLDVTVLEARDRVGGRV--WTLrfgdDGLYAELGAMRIPPSHTnllalarelGLP 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  67 LYQVYDKLG----LMEGRRFHHTDSWTSVRdehgneitiytDPDRLYDELIRispedtpfisRLCKDIKKLSRMETLVD- 141
Cdd:COG1231   83 LEPFPNENGnallYLGGKRVRAGEIAADLR-----------GVAELLAKLLR----------ALAAALDPWAHPAAELDr 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 142 MTILDIIRYIPYFSLMKRYkptvhdilsevkspvLRNLLTAGFG--WEGQSL--FFPLMGLAMQGAKNAgYPIGGS--LP 215
Cdd:COG1231  142 ESLAEWLRRNGASPSARRL---------------LGLLGAGEYGadPDELSLldLLRYAASAGGGAQQF-RIVGGMdqLP 205

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 499768298 216 caKAIEKRyldLGGVIRYKSKVTAIiteKNRAKGVRL--ADGTERYADYVIsCA 267
Cdd:COG1231  206 --RALAAE---LGDRIRLGAPVTRI---RQDGDGVTVttDDGGTVRADAVI-VT 250
PRK07233 PRK07233
hypothetical protein; Provisional
 5-265 3.04e-08

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 55.66  E-value: 3.04e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298   5 VLIIGGGMAGLSAGCFARMNGFETEILEMHTIPGGLCTAWTRKGYTFDLCIHWLCGSKpgTPLYQVYDKLGLMEGRRFHH 84
Cdd:PRK07233   2 IAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGLAASFEFGGLPIERFYHHIFKSD--EALLELLDELGLEDKLRWRE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298  85 TdswtsvrdehgneITIYTDPDRLYD-----ELIRISPedTPFISR-----LCKDIKKLSRMETLVDMTILDIIRyipyf 154
Cdd:PRK07233  80 T-------------KTGYYVDGKLYPlgtplELLRFPH--LSLIDKfrlglLTLLARRIKDWRALDKVPAEEWLR----- 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 155 slmKRYKPTVHDILsevkspvLRNLLTAGFG---------W----------EGQSLFFPLMGlamqgaknagYPIGGSLP 215
Cdd:PRK07233 140 ---RWSGEGVYEVF-------WEPLLESKFGdyaddvsaaWlwsrikrrgnRRYSLFGEKLG----------YLEGGFAT 199

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 499768298 216 CAKAIEKRYLDLGGVIRYKSKVTAIITEKNRAKGVRLADGTERYaDYVIS 265
Cdd:PRK07233 200 LIDALAEAIEARGGEIRLGTPVTSVVIDGGGVTGVEVDGEEEDF-DAVIS 248
PLN02268 PLN02268
probable polyamine oxidase
 3-148 1.19e-06

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 50.84  E-value: 1.19e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298   3 PSVLIIGGGMAGLSAGCFARMNGFETEILEMHTIPGGLCTAWTRKGYTFDLCIHWLCGSKPGTPLYQVYDKLGLmegrRF 82
Cdd:PLN02268   1 PSVIVIGGGIAGIAAARALHDASFKVTLLESRDRIGGRVHTDYSFGFPVDMGASWLHGVCNENPLAPLIGRLGL----PL 76

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 499768298  83 HHTDSWTSVRDEHGNEitIYTdpdrLYDELIRISPEDTPF-----ISRLCKDIKKLsRMETLVDMTILDII 148
Cdd:PLN02268  77 YRTSGDNSVLYDHDLE--SYA----LFDMDGNQVPQELVTkvgetFERILEETEKV-RDEHEEDMSLLQAI 140
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 1-116 1.27e-04

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 44.16  E-value: 1.27e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298   1 MAPSVLIIGGGMAGLSAGCFARMNGFETEILEMHTIPgglctAWTRKGYTFDlcihwlcgskPGTplYQVYDKLGLMEG- 79
Cdd:COG0654    2 MRTDVLIVGGGPAGLALALALARAGIRVTVVERAPPP-----RPDGRGIALS----------PRS--LELLRRLGLWDRl 64

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 499768298  80 -RRFHHTDSWTSVRDEHGNEITIYTDPDRLYDELIRIS 116
Cdd:COG0654   65 lARGAPIRGIRVRDGSDGRVLARFDAAETGLPAGLVVP 102
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 3-44 1.28e-04

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 44.08  E-value: 1.28e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 499768298   3 PSVLIIGGGMAGLSAGCFARMNGFETEILEMHTIPGGlctAW 44
Cdd:COG2072    7 VDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGG---TW 45
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
208-299 2.08e-04

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 43.36  E-value: 2.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 499768298 208 YPIGGSLPCAKAIE---KRYLDLGGVIRYKSKVTAIITEKNRAKGVRLADGTERyADYVISCADGHTT-IFEWLQGAYCD 283
Cdd:COG0665  142 DPDDGHVDPAKLVRalaRAARAAGVRIREGTPVTGLEREGGRVTGVRTERGTVR-ADAVVLAAGAWSArLLPMLGLRLPL 220

                         90
                 ....*....|....*.
gi 499768298 284 DTIRGYYQNLKPFPPI 299
Cdd:COG0665  221 RPVRGYVLVTEPLPDL 236
PRK07208 PRK07208
hypothetical protein; Provisional
 1-52 4.67e-04

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 42.57  E-value: 4.67e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 499768298   1 MAPSVLIIGGGMAGLSAGCFARMNGFETEILEMHTIPGGLCTAWTRKGYTFD 52
Cdd:PRK07208   3 NKKSVVIIGAGPAGLTAAYELLKRGYPVTVLEADPVVGGISRTVTYKGNRFD 54
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 5-39 1.10e-03

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 41.40  E-value: 1.10e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 499768298   5 VLIIGGGMAGLSAGCFARMNGFETEILEMHTIPGG 39
Cdd:PRK12771 140 VAVIGGGPAGLSAAYHLRRMGHAVTIFEAGPKLGG 174
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 4-40 1.26e-03

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 41.27  E-value: 1.26e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 499768298   4 SVLIIGGGMAGLSAGCFARMNGFETEILEMHTIPGGL 40
Cdd:COG0493  123 KVAVVGSGPAGLAAAYQLARAGHEVTVFEALDKPGGL 159
PRK13977 PRK13977
myosin-cross-reactive antigen; Provisional
 4-49 2.77e-03

myosin-cross-reactive antigen; Provisional


Pssm-ID: 237575  Cd Length: 576  Bit Score: 40.19  E-value: 2.77e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 499768298   4 SVLIIGGGMAGLSAGCF----ARMNGFETEILEMHTIPGGLCTAWTR--KGY 49
Cdd:PRK13977  24 KAYIIGSGLASLAAAVFlirdGQMPGENITILEELDVPGGSLDGAGNpeKGY 75
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
197-267 3.56e-03

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 39.74  E-value: 3.56e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 499768298 197 GLAMQGAK-----NAGYPIGGSLP--CAKAIEKRYLDLGGVIRYKSKVTAIITEkNRAKGVRLADGTERYADYVISCA 267
Cdd:COG1251  160 ALRKRGLEvtvveRAPRLLPRQLDeeAGALLQRLLEALGVEVRLGTGVTEIEGD-DRVTGVRLADGEELPADLVVVAI 236
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
5-46 3.79e-03

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 39.33  E-value: 3.79e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 499768298   5 VLIIGGGMAGLSAGCFARMNGFETEILEMHTiPGGLCTAWTR 46
Cdd:COG0492    3 VVIIGAGPAGLTAAIYAARAGLKTLVIEGGE-PGGQLATTKE 43
GlpB COG3075
Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism];
1-25 3.92e-03

Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism];


Pssm-ID: 442309  Cd Length: 415  Bit Score: 39.39  E-value: 3.92e-03
                         10        20
                 ....*....|....*....|....*
gi 499768298   1 MAPSVLIIGGGMAGLSAGCFARMNG 25
Cdd:COG3075    1 MKFDVVVIGGGLAGLTAAIRAAEAG 25
PRK05329 PRK05329
glycerol-3-phosphate dehydrogenase subunit GlpB;
5-31 4.22e-03

glycerol-3-phosphate dehydrogenase subunit GlpB;


Pssm-ID: 235412  Cd Length: 422  Bit Score: 39.45  E-value: 4.22e-03
                         10        20
                 ....*....|....*....|....*..
gi 499768298   5 VLIIGGGMAGLSAGCFARMNGFETEIL 31
Cdd:PRK05329   5 VLVIGGGLAGLTAALAAAEAGKRVALV 31
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
226-270 7.16e-03

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 38.41  E-value: 7.16e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 499768298 226 DLGGVIRYKSKVTAIITEKNRAKgVRLADGTERYADYVIsCADGH 270
Cdd:COG0644   98 EAGAEVRTGTRVTDVLRDDGRVV-VRTGDGEEIRADYVV-DADGA 140
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 3-41 9.87e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 38.07  E-value: 9.87e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 499768298    3 PSVLIIGGGMAGLSAGCFARMNGFETEILEMH-TIPGGLC 41
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIEDEgTCPYGGC 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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