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Conserved domains on  [gi|497367283|ref|WP_009681496|]
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MULTISPECIES: FAD-binding and (Fe-S)-binding domain-containing protein [Pseudomonas]

Protein Classification

FAD-binding and (Fe-S)-binding domain-containing protein( domain architecture ID 11416044)

FAD-binding and (Fe-S)-binding domain-containing protein, where the N-terminal FAD-binding and the C-terminal (Fe-S)-binding domains may function as oxidoreductases

Gene Ontology:  GO:0050660|GO:0046872|GO:0051536|GO:0071949|GO:0016491

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GlcD COG0277
FAD/FMN-containing lactate dehydrogenase/glycolate oxidase [Energy production and conversion];
14-537 1.10e-137

FAD/FMN-containing lactate dehydrogenase/glycolate oxidase [Energy production and conversion];


:

Pssm-ID: 440046 [Multi-domain]  Cd Length: 462  Bit Score: 421.22  E-value: 1.10e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   14 YPEFLEALRnSGFRGQISADYATRTVLATD-NSIYQRLPQAAVFPLDADDVARVATLMAEARfrhVKLTPRGGGTGTNGQ 92
Cdd:COG0277     3 TAALLAALR-AILAGRVLTDPADRAAYARDgNSLYRGRPDAVVRPRSTEDVAAVVRLAAEHG---VPVVPRGGGTGLAGG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   93 SL--TDGIVVDLSRhMNNILEINVEERWVRVQAGTVKDQLNAALKPYGLFFAPELSTSNRATVGGMINTDASGQGSCTYG 170
Cdd:COG0277    79 AVplDGGVVLDLSR-MNRILEVDPEDRTATVEAGVTLADLNAALAPHGLFFPPDPSSQGTATIGGNIATNAGGPRSLKYG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  171 KTRDHVLELHSVLLGGERLHSLPideaaleqacaapgrvgevyrmardiqqtqgdliertfpKLNRCLTGYDLAHLrdeq 250
Cdd:COG0277   158 LTRDNVLGLEVVLADGEVVRTGG---------------------------------------RVPKNVTGYDLFWL---- 194

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  251 grfnlnsvLCGAEGSLGYVVEAKLNVLPIPKYAVLVNVRYTSFMDALRDANALMAH--KPLSIETVDSKVLMLamkdivw 328
Cdd:COG0277   195 --------LVGSEGTLGVITEATLRLHPLPEAVATALVAFPDLEAAAAAVRALLAAgiAPAALELMDRAALAL------- 259

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  329 hsVAEYFPADPERPTLGINLVEFCGDEPAQVNAKVQAFLQHLQSDTSVErlgHTLAEGSEAVTRVYTMRKRSVGLLGNVE 408
Cdd:COG0277   260 --VEAAPPLGLPEDGGALLLVEFDGDDAEEVEAQLARLRAILEAGGATD---VRVAADGAERERLWKARKAALPALGRLD 334

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  409 GEVRpqpFVEDTAVPPEQLADYIADFRALLDGYGLAYGMFGHVDAGVLHVRPALDMKDPAQAALVKPISDAVAALTKRYG 488
Cdd:COG0277   335 GGAK---LLEDVAVPPSRLPELLRELGALAAKYGLRATAFGHAGDGNLHVRILFDPADPEEVERARAAAEEIFDLVAELG 411

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 497367283  489 GLLWGEHGKGL-RSEYVPEYFGE-LYPALQRLKGAFDPHNQLNPGKICTPP 537
Cdd:COG0277   412 GSISGEHGIGRlKAEFLPAEYGPaALALLRRIKAAFDPDGILNPGKILPPP 462
GlpC COG0247
Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy ...
 490-1002 1.56e-79

Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy production and conversion];


:

Pssm-ID: 440017 [Multi-domain]  Cd Length: 420  Bit Score: 265.79  E-value: 1.56e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  490 LLWGEHGKGLRSEYVPEYFGE-LYPALQRLKGAFDPHNQLNPGKICTPPDSAEGLTKVDgvtlrgDLDRSIDERVWQDFG 568
Cdd:COG0247     1 LSGGHGGGLKAEHGTGRFMAPfLELELGKIKYAFDPDNKLNPGKIGLLNPGVELLGDGD------LHDKNLKTLPWKELL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  569 SAVH-CNGNGACYnydpndAMCPSWKATRERQHSPKGRASLMREWLRlqgeanidvlaaarnkvswlkglparlrnnrar 647
Cdd:COG0247    75 DALDaCVGCGFCR------AMCPSYKATGDEKDSPRGRINLLREVLE--------------------------------- 115

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  648 NQGQADFSHEVYDAMAGCLACKSCAGQCPIKVNVPDFRSRFLELYHGRYQRPLRDYLIGSLEFTIPylahapglynavmg 727
Cdd:COG0247   116 GELPLDLSEEVYEVLDLCLTCKACETACPSGVDIADLIAEARAQLVERGGRPLRDRLLRTFPDRVP-------------- 181

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  728 skwvsrllaekvgmvdsplisrfnfqatltrcrvgvatvpalrelTPAQRERSIVLVQDAFTRYFETPLLSAFIDLANRL 807
Cdd:COG0247   182 ---------------------------------------------AADKEGAEVLLFPGCFTNYFDPEIGKAAVRLLEAA 216

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  808 GHRVFLAP-YSANGKPLHVQGFLGAFAKAAIRNasqLKALADCGVP-LVGLDPAMTLVYRQEYQKVPGMDGCPQVLLPQE 885
Cdd:COG0247   217 GVEVVLPPeELCCGAPALSKGDLDLARKLARRN---IEALERLGVKaIVTTCPSCGLTLKDEYPELLGDRVAFEVLDISE 293

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  886 WLMNVLPE---QAPTAPGNFRLMAHCTEKtNVPASTRQWEQVFARL-GLKLV--TEATGCCGMSGTYGHEARnqETSRTI 959
Cdd:COG0247   294 FLAELILEgklKLKPLGEKVTYHDPCHLG-RGGGVYDAPRELLKAIpGVEVVemPEDSGCCGGAGGYGFEEP--ELSMRI 370

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*...
gi 497367283  960 FEQsWATKLDKEGEP--LATGYSCRSQVKRMTE---RQMRHPLEVVLQ 1002
Cdd:COG0247   371 GER-KLEQIRATGADvvVTACPSCRTQLEDGTKeygIEVKHPVELLAE 417
 
Name Accession Description Interval E-value
GlcD COG0277
FAD/FMN-containing lactate dehydrogenase/glycolate oxidase [Energy production and conversion];
14-537 1.10e-137

FAD/FMN-containing lactate dehydrogenase/glycolate oxidase [Energy production and conversion];


Pssm-ID: 440046 [Multi-domain]  Cd Length: 462  Bit Score: 421.22  E-value: 1.10e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   14 YPEFLEALRnSGFRGQISADYATRTVLATD-NSIYQRLPQAAVFPLDADDVARVATLMAEARfrhVKLTPRGGGTGTNGQ 92
Cdd:COG0277     3 TAALLAALR-AILAGRVLTDPADRAAYARDgNSLYRGRPDAVVRPRSTEDVAAVVRLAAEHG---VPVVPRGGGTGLAGG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   93 SL--TDGIVVDLSRhMNNILEINVEERWVRVQAGTVKDQLNAALKPYGLFFAPELSTSNRATVGGMINTDASGQGSCTYG 170
Cdd:COG0277    79 AVplDGGVVLDLSR-MNRILEVDPEDRTATVEAGVTLADLNAALAPHGLFFPPDPSSQGTATIGGNIATNAGGPRSLKYG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  171 KTRDHVLELHSVLLGGERLHSLPideaaleqacaapgrvgevyrmardiqqtqgdliertfpKLNRCLTGYDLAHLrdeq 250
Cdd:COG0277   158 LTRDNVLGLEVVLADGEVVRTGG---------------------------------------RVPKNVTGYDLFWL---- 194

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  251 grfnlnsvLCGAEGSLGYVVEAKLNVLPIPKYAVLVNVRYTSFMDALRDANALMAH--KPLSIETVDSKVLMLamkdivw 328
Cdd:COG0277   195 --------LVGSEGTLGVITEATLRLHPLPEAVATALVAFPDLEAAAAAVRALLAAgiAPAALELMDRAALAL------- 259

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  329 hsVAEYFPADPERPTLGINLVEFCGDEPAQVNAKVQAFLQHLQSDTSVErlgHTLAEGSEAVTRVYTMRKRSVGLLGNVE 408
Cdd:COG0277   260 --VEAAPPLGLPEDGGALLLVEFDGDDAEEVEAQLARLRAILEAGGATD---VRVAADGAERERLWKARKAALPALGRLD 334

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  409 GEVRpqpFVEDTAVPPEQLADYIADFRALLDGYGLAYGMFGHVDAGVLHVRPALDMKDPAQAALVKPISDAVAALTKRYG 488
Cdd:COG0277   335 GGAK---LLEDVAVPPSRLPELLRELGALAAKYGLRATAFGHAGDGNLHVRILFDPADPEEVERARAAAEEIFDLVAELG 411

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 497367283  489 GLLWGEHGKGL-RSEYVPEYFGE-LYPALQRLKGAFDPHNQLNPGKICTPP 537
Cdd:COG0277   412 GSISGEHGIGRlKAEFLPAEYGPaALALLRRIKAAFDPDGILNPGKILPPP 462
GlpC COG0247
Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy ...
 490-1002 1.56e-79

Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy production and conversion];


Pssm-ID: 440017 [Multi-domain]  Cd Length: 420  Bit Score: 265.79  E-value: 1.56e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  490 LLWGEHGKGLRSEYVPEYFGE-LYPALQRLKGAFDPHNQLNPGKICTPPDSAEGLTKVDgvtlrgDLDRSIDERVWQDFG 568
Cdd:COG0247     1 LSGGHGGGLKAEHGTGRFMAPfLELELGKIKYAFDPDNKLNPGKIGLLNPGVELLGDGD------LHDKNLKTLPWKELL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  569 SAVH-CNGNGACYnydpndAMCPSWKATRERQHSPKGRASLMREWLRlqgeanidvlaaarnkvswlkglparlrnnrar 647
Cdd:COG0247    75 DALDaCVGCGFCR------AMCPSYKATGDEKDSPRGRINLLREVLE--------------------------------- 115

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  648 NQGQADFSHEVYDAMAGCLACKSCAGQCPIKVNVPDFRSRFLELYHGRYQRPLRDYLIGSLEFTIPylahapglynavmg 727
Cdd:COG0247   116 GELPLDLSEEVYEVLDLCLTCKACETACPSGVDIADLIAEARAQLVERGGRPLRDRLLRTFPDRVP-------------- 181

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  728 skwvsrllaekvgmvdsplisrfnfqatltrcrvgvatvpalrelTPAQRERSIVLVQDAFTRYFETPLLSAFIDLANRL 807
Cdd:COG0247   182 ---------------------------------------------AADKEGAEVLLFPGCFTNYFDPEIGKAAVRLLEAA 216

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  808 GHRVFLAP-YSANGKPLHVQGFLGAFAKAAIRNasqLKALADCGVP-LVGLDPAMTLVYRQEYQKVPGMDGCPQVLLPQE 885
Cdd:COG0247   217 GVEVVLPPeELCCGAPALSKGDLDLARKLARRN---IEALERLGVKaIVTTCPSCGLTLKDEYPELLGDRVAFEVLDISE 293

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  886 WLMNVLPE---QAPTAPGNFRLMAHCTEKtNVPASTRQWEQVFARL-GLKLV--TEATGCCGMSGTYGHEARnqETSRTI 959
Cdd:COG0247   294 FLAELILEgklKLKPLGEKVTYHDPCHLG-RGGGVYDAPRELLKAIpGVEVVemPEDSGCCGGAGGYGFEEP--ELSMRI 370

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*...
gi 497367283  960 FEQsWATKLDKEGEP--LATGYSCRSQVKRMTE---RQMRHPLEVVLQ 1002
Cdd:COG0247   371 GER-KLEQIRATGADvvVTACPSCRTQLEDGTKeygIEVKHPVELLAE 417
FAD-oxidase_C pfam02913
FAD linked oxidases, C-terminal domain; This domain has a ferredoxin-like fold.
 279-533 1.75e-66

FAD linked oxidases, C-terminal domain; This domain has a ferredoxin-like fold.


Pssm-ID: 397178  Cd Length: 248  Bit Score: 223.73  E-value: 1.75e-66
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   279 IPKYAVLVNVRYTSFMDALRDANALMAHK--PLSIETVDSKVLMLAMKDIVWHSvaeyfpaDPERPTLGINLVEFCGDEP 356
Cdd:pfam02913    1 LPEVRAVALVGFPSFEAAVKAVREIARAGiiPAALELMDNDALDLVEATLGFPK-------GLPRDAAALLLVEFEGDDE 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   357 AQVNAKVQAFLQHLQSDTSVERLGhtlAEGSEAVTRVYTMRKRSVGLlGNVEGEVRPQPFVEDTAVPPEQLADYIADFRA 436
Cdd:pfam02913   74 ETAEEELEAVEAILEAGGAGDVVV---ATDEAEAERLWAARKYALPL-RDALGGAGPAVFSEDVSVPRSRLADLVRDIKE 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   437 LLDGYGLAYGMFGHVDAGVLHVRPALDMKDPAQAALVKPISDAVAALTKRYGGLLWGEHGKGL-RSEYVPEYFGE-LYPA 514
Cdd:pfam02913  150 LLDKYGLVVCLFGHAGDGNLHLYILFDFRDPEQEERAEKLFDEIMDLALELGGSISGEHGVGRdKKPYLEREFGEeGLAL 229

                          250
                   ....*....|....*....
gi 497367283   515 LQRLKGAFDPHNQLNPGKI 533
Cdd:pfam02913  230 MRRIKAAFDPKGILNPGKV 248
glcD TIGR00387
glycolate oxidase, subunit GlcD; This protein, the glycolate oxidase GlcD subunit, is similar ...
 55-532 1.03e-48

glycolate oxidase, subunit GlcD; This protein, the glycolate oxidase GlcD subunit, is similar in sequence to that of several D-lactate dehydrogenases, including that of E. coli. The glycolate oxidase has been found to have some D-lactate dehydrogenase activity. [Energy metabolism, Other]


Pssm-ID: 273050 [Multi-domain]  Cd Length: 413  Bit Score: 178.81  E-value: 1.03e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283    55 VFPLDADDVARVATLMAEARfrhVKLTPRGGGTGTNGQSL-TDGIVVDLSRHMNNILEINVEERWVRVQAGTVKDQLNAA 133
Cdd:TIGR00387    2 VFPKNTEQVARILKLCHEHR---IPIVPRGAGTGLSGGALpEEGGLVLVFKHMNKILEIDVVNLTAVVQPGVRNLELEQA 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   134 LKPYGLFFAPELSTSNRATVGGMINTDASGQGSCTYGKTRDHVLELHSVLLGGErlhslpideaaleqacaapgrvgevy 213
Cdd:TIGR00387   79 VEEHNLFYPPDPSSQISSTIGGNIAENAGGMRGLKYGTTVDYVLGLEVVTADGE-------------------------- 132

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   214 rmardiqqtqgdlIERTFPKLNRCLTGYDLAHLrdeqgrfnlnsvLCGAEGSLGYVVEAKLNVLPIPKYAVLVNVRYTSF 293
Cdd:TIGR00387  133 -------------ILRIGGKTAKDVAGYDLTGL------------FVGSEGTLGIVTEATLKLLPKPENIVVALAFFDSI 187

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   294 MDALRDANALMAHK--PLSIETVDSKVLMlamkdivwhSVAEYFPADPERPTLGINLVEF-CGDEPAQVN-AKVQaflQH 369
Cdd:TIGR00387  188 EKAMQAVYDIIAAGiiPAGMEFLDNLSIK---------AVEDISGIGLPKDAGAILLVEIdGVHEAVERDeEKIE---QI 255

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   370 LQSDTSVErlgHTLAEGSEAVTRVYTMRKRSVGLLGnvegEVRPQPFVEDTAVPPEQLADYIADFRALLDGYGLAYGMFG 449
Cdd:TIGR00387  256 CRKNGAVD---VQIAQDEEERALLWAGRRNAFKAAS----KLSPLYLIEDGTVPRSKLPEALRGIADIASKYDFTIANFG 328

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   450 HVDAGVLHVRPALDMKDPAQAALVKPISDAVAALTKRYGGLLWGEHGKGL-RSEYVPEYFGEL-YPALQRLKGAFDPHNQ 527
Cdd:TIGR00387  329 HAGDGNLHPTILTDPEDKGEMERVEEAGGEIFELAIELGGTISGEHGIGVvKAEFMPYKFNEKeLETMRAIKKAFDPDNI 408


                   ....*
gi 497367283   528 LNPGK 532
Cdd:TIGR00387  409 LNPGK 413
PLN02805 PLN02805
D-lactate dehydrogenase [cytochrome]
 16-536 6.61e-36

D-lactate dehydrogenase [cytochrome]


Pssm-ID: 178402 [Multi-domain]  Cd Length: 555  Bit Score: 144.38  E-value: 6.61e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   16 EFLEALRnSGFRGQISADYATRTVLAT-DNSIYQ--RLPQAAVFPLDADDVARVatLMAEARFRhVKLTPRGGGTGTNGQ 92
Cdd:PLN02805   97 ELIDELK-AILQDNMTLDYDERYFHGKpQNSFHKavNIPDVVVFPRSEEEVSKI--VKSCNKYK-VPIVPYGGATSIEGH 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   93 SLT--DGIVVDLSRhMNNILEINVEERWVRVQAGTVKDQLNAALKPYGLFFApeLSTSNRATVGGMINTDASGQGSCTYG 170
Cdd:PLN02805  173 TLAphGGVCIDMSL-MKSVKALHVEDMDVVVEPGIGWLELNEYLEPYGLFFP--LDPGPGATIGGMCATRCSGSLAVRYG 249

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  171 KTRDHVLELHSVLlggerlhslpideaaleqacaapgrvgevyrmardiqqTQGDLIeRTFPKLNRCLTGYDLAHLrdeq 250
Cdd:PLN02805  250 TMRDNVISLKVVL--------------------------------------PNGDVV-KTASRARKSAAGYDLTRL---- 286

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  251 grfnlnsvLCGAEGSLGYVVEAKLNVLPIPKYAVLVNVRYTSFMDALRDANALMahkpLSIETVdSKVLMLAMKDIVWHS 330
Cdd:PLN02805  287 --------VIGSEGTLGVITEVTLRLQKIPQHSVVAMCNFPTIKDAADVAIATM----LSGIQV-SRVELLDEVQIRAIN 353

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  331 VAEYfPADPERPTLginLVEFCGDEpaqVNAKVQAFL------QHLQSDtsverlgHTLAEGSEAVTRVYTMRKRSvgLL 404
Cdd:PLN02805  354 MANG-KNLPEAPTL---MFEFIGTE---AYAREQTLIvqkiasKHNGSD-------FVFAEEPEAKKELWKIRKEA--LW 417

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  405 GNVEGEVRPQPFVEDTAVPPEQLADYIADFRALLDGYGLAYGMFGHVDAGVLHVRPALDMKDPAQAALVKPISDAVAALT 484
Cdd:PLN02805  418 ACFAMEPKYEAMITDVCVPLSHLAELISRSKKELDASPLVCTVIAHAGDGNFHTIILFDPSQEDQRREAERLNHFMVHTA 497

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 497367283  485 KRYGGLLWGEHGKGL-RSEYVPEYFG-ELYPALQRLKGAFDPHNQLNPGKICTP 536
Cdd:PLN02805  498 LSMEGTCTGEHGVGTgKMKYLEKELGiEALQTMKRIKKALDPNNIMNPGKLIPP 551
glpC PRK11168
anaerobic glycerol-3-phosphate dehydrogenase subunit C;
656-999 7.67e-21

anaerobic glycerol-3-phosphate dehydrogenase subunit C;


Pssm-ID: 236869 [Multi-domain]  Cd Length: 396  Bit Score: 96.09  E-value: 7.67e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  656 HEVYDAMAGCLACKSCAGQCPIKVNVPDFRSRFLELYHGRYQRPLRDYLIGSLEFTIPYLAHAPGLYNAVMGSKWVsRLL 735
Cdd:PRK11168   47 ALYDESLKYCSNCKRCEVACPSGVKIGDIIQRARAKYVTERGPPLRDRILSHTDLMGSLATPFAPLVNAATGLKPV-RWL 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  736 AEKVGMVDS--PLiSRFNFQATLTRCRVGVATVPalreltpaQRERSIVLVQDAFTRYFETPLLSAFIDLANRLGHRVFL 813
Cdd:PRK11168  126 LEKTLGIDHrrPL-PKYAFGTFRRWYRKQAAQQA--------QYKKQVAYFHGCYVNYNHPQLGKDLVKVLNAMGYEVLL 196

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  814 APYSANGKPLHVQGFLGAFAKAAIRNASQLKALADCGVPLVGLDPAMTLVYRQEYQKVPGMDG---CPQVLLPQEWLMNV 890
Cdd:PRK11168  197 PKEKCCGLPLIANGFLDKARKQAEFNVESLREAIEKGIPVIATSSSCTLTLRDEYPELLGVDNagvRDHIEDATEFLRRL 276

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  891 L--PEQAPTAPGNFRLMAH--C-TEKTnvpASTRQWEQVFARL-GLKLVTEATGCCGMSGTYGHEARNQETSRTI----F 960
Cdd:PRK11168  277 LdqGKLLPLKPLPLKVAYHtpChLEKQ---GWGLYTLELLRLIpGLEVVVLDSQCCGIAGTYGFKKEKYETSQAIgaplF 353

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 497367283  961 EQSWATKLD---KEGEplatgySCRSQVKRMTERQMRHPLEV 999
Cdd:PRK11168  354 RQIEESGADlvvTDCE------TCKWQIEMSTGLECEHPITL 389
 
Name Accession Description Interval E-value
GlcD COG0277
FAD/FMN-containing lactate dehydrogenase/glycolate oxidase [Energy production and conversion];
14-537 1.10e-137

FAD/FMN-containing lactate dehydrogenase/glycolate oxidase [Energy production and conversion];


Pssm-ID: 440046 [Multi-domain]  Cd Length: 462  Bit Score: 421.22  E-value: 1.10e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   14 YPEFLEALRnSGFRGQISADYATRTVLATD-NSIYQRLPQAAVFPLDADDVARVATLMAEARfrhVKLTPRGGGTGTNGQ 92
Cdd:COG0277     3 TAALLAALR-AILAGRVLTDPADRAAYARDgNSLYRGRPDAVVRPRSTEDVAAVVRLAAEHG---VPVVPRGGGTGLAGG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   93 SL--TDGIVVDLSRhMNNILEINVEERWVRVQAGTVKDQLNAALKPYGLFFAPELSTSNRATVGGMINTDASGQGSCTYG 170
Cdd:COG0277    79 AVplDGGVVLDLSR-MNRILEVDPEDRTATVEAGVTLADLNAALAPHGLFFPPDPSSQGTATIGGNIATNAGGPRSLKYG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  171 KTRDHVLELHSVLLGGERLHSLPideaaleqacaapgrvgevyrmardiqqtqgdliertfpKLNRCLTGYDLAHLrdeq 250
Cdd:COG0277   158 LTRDNVLGLEVVLADGEVVRTGG---------------------------------------RVPKNVTGYDLFWL---- 194

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  251 grfnlnsvLCGAEGSLGYVVEAKLNVLPIPKYAVLVNVRYTSFMDALRDANALMAH--KPLSIETVDSKVLMLamkdivw 328
Cdd:COG0277   195 --------LVGSEGTLGVITEATLRLHPLPEAVATALVAFPDLEAAAAAVRALLAAgiAPAALELMDRAALAL------- 259

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  329 hsVAEYFPADPERPTLGINLVEFCGDEPAQVNAKVQAFLQHLQSDTSVErlgHTLAEGSEAVTRVYTMRKRSVGLLGNVE 408
Cdd:COG0277   260 --VEAAPPLGLPEDGGALLLVEFDGDDAEEVEAQLARLRAILEAGGATD---VRVAADGAERERLWKARKAALPALGRLD 334

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  409 GEVRpqpFVEDTAVPPEQLADYIADFRALLDGYGLAYGMFGHVDAGVLHVRPALDMKDPAQAALVKPISDAVAALTKRYG 488
Cdd:COG0277   335 GGAK---LLEDVAVPPSRLPELLRELGALAAKYGLRATAFGHAGDGNLHVRILFDPADPEEVERARAAAEEIFDLVAELG 411

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|.
gi 497367283  489 GLLWGEHGKGL-RSEYVPEYFGE-LYPALQRLKGAFDPHNQLNPGKICTPP 537
Cdd:COG0277   412 GSISGEHGIGRlKAEFLPAEYGPaALALLRRIKAAFDPDGILNPGKILPPP 462
GlpC COG0247
Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy ...
 490-1002 1.56e-79

Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy production and conversion];


Pssm-ID: 440017 [Multi-domain]  Cd Length: 420  Bit Score: 265.79  E-value: 1.56e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  490 LLWGEHGKGLRSEYVPEYFGE-LYPALQRLKGAFDPHNQLNPGKICTPPDSAEGLTKVDgvtlrgDLDRSIDERVWQDFG 568
Cdd:COG0247     1 LSGGHGGGLKAEHGTGRFMAPfLELELGKIKYAFDPDNKLNPGKIGLLNPGVELLGDGD------LHDKNLKTLPWKELL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  569 SAVH-CNGNGACYnydpndAMCPSWKATRERQHSPKGRASLMREWLRlqgeanidvlaaarnkvswlkglparlrnnrar 647
Cdd:COG0247    75 DALDaCVGCGFCR------AMCPSYKATGDEKDSPRGRINLLREVLE--------------------------------- 115

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  648 NQGQADFSHEVYDAMAGCLACKSCAGQCPIKVNVPDFRSRFLELYHGRYQRPLRDYLIGSLEFTIPylahapglynavmg 727
Cdd:COG0247   116 GELPLDLSEEVYEVLDLCLTCKACETACPSGVDIADLIAEARAQLVERGGRPLRDRLLRTFPDRVP-------------- 181

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  728 skwvsrllaekvgmvdsplisrfnfqatltrcrvgvatvpalrelTPAQRERSIVLVQDAFTRYFETPLLSAFIDLANRL 807
Cdd:COG0247   182 ---------------------------------------------AADKEGAEVLLFPGCFTNYFDPEIGKAAVRLLEAA 216

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  808 GHRVFLAP-YSANGKPLHVQGFLGAFAKAAIRNasqLKALADCGVP-LVGLDPAMTLVYRQEYQKVPGMDGCPQVLLPQE 885
Cdd:COG0247   217 GVEVVLPPeELCCGAPALSKGDLDLARKLARRN---IEALERLGVKaIVTTCPSCGLTLKDEYPELLGDRVAFEVLDISE 293

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  886 WLMNVLPE---QAPTAPGNFRLMAHCTEKtNVPASTRQWEQVFARL-GLKLV--TEATGCCGMSGTYGHEARnqETSRTI 959
Cdd:COG0247   294 FLAELILEgklKLKPLGEKVTYHDPCHLG-RGGGVYDAPRELLKAIpGVEVVemPEDSGCCGGAGGYGFEEP--ELSMRI 370

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*...
gi 497367283  960 FEQsWATKLDKEGEP--LATGYSCRSQVKRMTE---RQMRHPLEVVLQ 1002
Cdd:COG0247   371 GER-KLEQIRATGADvvVTACPSCRTQLEDGTKeygIEVKHPVELLAE 417
FAD-oxidase_C pfam02913
FAD linked oxidases, C-terminal domain; This domain has a ferredoxin-like fold.
 279-533 1.75e-66

FAD linked oxidases, C-terminal domain; This domain has a ferredoxin-like fold.


Pssm-ID: 397178  Cd Length: 248  Bit Score: 223.73  E-value: 1.75e-66
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   279 IPKYAVLVNVRYTSFMDALRDANALMAHK--PLSIETVDSKVLMLAMKDIVWHSvaeyfpaDPERPTLGINLVEFCGDEP 356
Cdd:pfam02913    1 LPEVRAVALVGFPSFEAAVKAVREIARAGiiPAALELMDNDALDLVEATLGFPK-------GLPRDAAALLLVEFEGDDE 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   357 AQVNAKVQAFLQHLQSDTSVERLGhtlAEGSEAVTRVYTMRKRSVGLlGNVEGEVRPQPFVEDTAVPPEQLADYIADFRA 436
Cdd:pfam02913   74 ETAEEELEAVEAILEAGGAGDVVV---ATDEAEAERLWAARKYALPL-RDALGGAGPAVFSEDVSVPRSRLADLVRDIKE 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   437 LLDGYGLAYGMFGHVDAGVLHVRPALDMKDPAQAALVKPISDAVAALTKRYGGLLWGEHGKGL-RSEYVPEYFGE-LYPA 514
Cdd:pfam02913  150 LLDKYGLVVCLFGHAGDGNLHLYILFDFRDPEQEERAEKLFDEIMDLALELGGSISGEHGVGRdKKPYLEREFGEeGLAL 229

                          250
                   ....*....|....*....
gi 497367283   515 LQRLKGAFDPHNQLNPGKI 533
Cdd:pfam02913  230 MRRIKAAFDPKGILNPGKV 248
glcD TIGR00387
glycolate oxidase, subunit GlcD; This protein, the glycolate oxidase GlcD subunit, is similar ...
 55-532 1.03e-48

glycolate oxidase, subunit GlcD; This protein, the glycolate oxidase GlcD subunit, is similar in sequence to that of several D-lactate dehydrogenases, including that of E. coli. The glycolate oxidase has been found to have some D-lactate dehydrogenase activity. [Energy metabolism, Other]


Pssm-ID: 273050 [Multi-domain]  Cd Length: 413  Bit Score: 178.81  E-value: 1.03e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283    55 VFPLDADDVARVATLMAEARfrhVKLTPRGGGTGTNGQSL-TDGIVVDLSRHMNNILEINVEERWVRVQAGTVKDQLNAA 133
Cdd:TIGR00387    2 VFPKNTEQVARILKLCHEHR---IPIVPRGAGTGLSGGALpEEGGLVLVFKHMNKILEIDVVNLTAVVQPGVRNLELEQA 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   134 LKPYGLFFAPELSTSNRATVGGMINTDASGQGSCTYGKTRDHVLELHSVLLGGErlhslpideaaleqacaapgrvgevy 213
Cdd:TIGR00387   79 VEEHNLFYPPDPSSQISSTIGGNIAENAGGMRGLKYGTTVDYVLGLEVVTADGE-------------------------- 132

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   214 rmardiqqtqgdlIERTFPKLNRCLTGYDLAHLrdeqgrfnlnsvLCGAEGSLGYVVEAKLNVLPIPKYAVLVNVRYTSF 293
Cdd:TIGR00387  133 -------------ILRIGGKTAKDVAGYDLTGL------------FVGSEGTLGIVTEATLKLLPKPENIVVALAFFDSI 187

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   294 MDALRDANALMAHK--PLSIETVDSKVLMlamkdivwhSVAEYFPADPERPTLGINLVEF-CGDEPAQVN-AKVQaflQH 369
Cdd:TIGR00387  188 EKAMQAVYDIIAAGiiPAGMEFLDNLSIK---------AVEDISGIGLPKDAGAILLVEIdGVHEAVERDeEKIE---QI 255

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   370 LQSDTSVErlgHTLAEGSEAVTRVYTMRKRSVGLLGnvegEVRPQPFVEDTAVPPEQLADYIADFRALLDGYGLAYGMFG 449
Cdd:TIGR00387  256 CRKNGAVD---VQIAQDEEERALLWAGRRNAFKAAS----KLSPLYLIEDGTVPRSKLPEALRGIADIASKYDFTIANFG 328

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   450 HVDAGVLHVRPALDMKDPAQAALVKPISDAVAALTKRYGGLLWGEHGKGL-RSEYVPEYFGEL-YPALQRLKGAFDPHNQ 527
Cdd:TIGR00387  329 HAGDGNLHPTILTDPEDKGEMERVEEAGGEIFELAIELGGTISGEHGIGVvKAEFMPYKFNEKeLETMRAIKKAFDPDNI 408


                   ....*
gi 497367283   528 LNPGK 532
Cdd:TIGR00387  409 LNPGK 413
FAD_binding_4 pfam01565
FAD binding domain; This family consists of various enzymes that use FAD as a co-factor, most ...
 51-190 9.61e-40

FAD binding domain; This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidizes the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.


Pssm-ID: 426326 [Multi-domain]  Cd Length: 139  Bit Score: 143.50  E-value: 9.61e-40
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283    51 PQAAVFPLDADDVARVatlMAEARFRHVKLTPRGGGTGTNGQS-LTDGIVVDLSRhMNNILEINVEERWVRVQAGTVKDQ 129
Cdd:pfam01565    1 PAAVVLPESEEEVAAI---VRLANENGLPVLPRGGGSSLLGGAvQTGGIVLDLSR-LNGILEIDPEDGTATVEAGVTLGD 76

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 497367283   130 LNAALKPYGLFFAPELSTSNRATVGGMINTDASGQGSCTYGKTRDHVLELHSVLLGGERLH 190
Cdd:pfam01565   77 LVRALAAKGLLLGLDPGSGIPGTVGGAIATNAGGYGSEKYGLTRDNVLGLEVVLADGEVVR 137
PLN02805 PLN02805
D-lactate dehydrogenase [cytochrome]
 16-536 6.61e-36

D-lactate dehydrogenase [cytochrome]


Pssm-ID: 178402 [Multi-domain]  Cd Length: 555  Bit Score: 144.38  E-value: 6.61e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   16 EFLEALRnSGFRGQISADYATRTVLAT-DNSIYQ--RLPQAAVFPLDADDVARVatLMAEARFRhVKLTPRGGGTGTNGQ 92
Cdd:PLN02805   97 ELIDELK-AILQDNMTLDYDERYFHGKpQNSFHKavNIPDVVVFPRSEEEVSKI--VKSCNKYK-VPIVPYGGATSIEGH 172

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   93 SLT--DGIVVDLSRhMNNILEINVEERWVRVQAGTVKDQLNAALKPYGLFFApeLSTSNRATVGGMINTDASGQGSCTYG 170
Cdd:PLN02805  173 TLAphGGVCIDMSL-MKSVKALHVEDMDVVVEPGIGWLELNEYLEPYGLFFP--LDPGPGATIGGMCATRCSGSLAVRYG 249

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  171 KTRDHVLELHSVLlggerlhslpideaaleqacaapgrvgevyrmardiqqTQGDLIeRTFPKLNRCLTGYDLAHLrdeq 250
Cdd:PLN02805  250 TMRDNVISLKVVL--------------------------------------PNGDVV-KTASRARKSAAGYDLTRL---- 286

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  251 grfnlnsvLCGAEGSLGYVVEAKLNVLPIPKYAVLVNVRYTSFMDALRDANALMahkpLSIETVdSKVLMLAMKDIVWHS 330
Cdd:PLN02805  287 --------VIGSEGTLGVITEVTLRLQKIPQHSVVAMCNFPTIKDAADVAIATM----LSGIQV-SRVELLDEVQIRAIN 353

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  331 VAEYfPADPERPTLginLVEFCGDEpaqVNAKVQAFL------QHLQSDtsverlgHTLAEGSEAVTRVYTMRKRSvgLL 404
Cdd:PLN02805  354 MANG-KNLPEAPTL---MFEFIGTE---AYAREQTLIvqkiasKHNGSD-------FVFAEEPEAKKELWKIRKEA--LW 417

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  405 GNVEGEVRPQPFVEDTAVPPEQLADYIADFRALLDGYGLAYGMFGHVDAGVLHVRPALDMKDPAQAALVKPISDAVAALT 484
Cdd:PLN02805  418 ACFAMEPKYEAMITDVCVPLSHLAELISRSKKELDASPLVCTVIAHAGDGNFHTIILFDPSQEDQRREAERLNHFMVHTA 497

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 497367283  485 KRYGGLLWGEHGKGL-RSEYVPEYFG-ELYPALQRLKGAFDPHNQLNPGKICTP 536
Cdd:PLN02805  498 LSMEGTCTGEHGVGTgKMKYLEKELGiEALQTMKRIKKALDPNNIMNPGKLIPP 551
PRK11230 PRK11230
glycolate oxidase subunit GlcD; Provisional
 45-532 2.20e-23

glycolate oxidase subunit GlcD; Provisional


Pssm-ID: 183043 [Multi-domain]  Cd Length: 499  Bit Score: 105.24  E-value: 2.20e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   45 SIYQRLPQAAVFPldaDDVARVATLMAEARFRHVKLTPRGGGTGTNGQS--LTDGIVVDLSRhMNNILEINVEERWVRVQ 122
Cdd:PRK11230   50 SAYRTRPLLVVLP---KQMEQVQALLAVCHRLRVPVVARGAGTGLSGGAlpLEKGVLLVMAR-FNRILDINPVGRRARVQ 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  123 AGTVKDQLNAALKPYGLFFAPELSTSNRATVGGMINTDASGQGSCTYGKTRDHVLELHSVLLGGERLhSLPIDeaaleqA 202
Cdd:PRK11230  126 PGVRNLAISQAAAPHGLYYAPDPSSQIACSIGGNVAENAGGVHCLKYGLTVHNLLKVEILTLDGEAL-TLGSD------A 198

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  203 CAAPGrvgevyrmardiqqtqgdliertfpklnrcltgydlahlrdeqgrFNLNSVLCGAEGSLGYVVEAKLNVLPIPKY 282
Cdd:PRK11230  199 LDSPG---------------------------------------------FDLLALFTGSEGMLGVVTEVTVKLLPKPPV 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  283 AVLVNVRYTSFMDALRDANALMAHK--PLSIETVDSkVLMLAMKDIVwHsvAEYfPADPErptlGINLVEFCGDEpAQVN 360
Cdd:PRK11230  234 ARVLLASFDSVEKAGLAVGDIIAAGiiPGGLEMMDN-LSIRAAEDFI-H--AGY-PVDAE----AILLCELDGVE-SDVQ 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  361 ---AKVQAFLQHLQSdTSVeRLGHTLAEGseavTRVYTMRKRSVGLLGNVEgevrPQPFVEDTAVPPEQLADYIADFRAL 437
Cdd:PRK11230  304 edcERVNDILLKAGA-TDV-RLAQDEAER----VRFWAGRKNAFPAVGRIS----PDYYCMDGTIPRRELPGVLEGIARL 373

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  438 LDGYGLAYGMFGHVDAGVLHVRPALDMKDPAQAALVKPISDAVAALTKRYGGLLWGEHGKGLR--SEYVPEYFGELYPAL 515
Cdd:PRK11230  374 SQQYGLRVANVFHAGDGNMHPLILFDANEPGELERAEALGGKILELCVEVGGSITGEHGVGREkiNQMCAQFNSDEITLF 453

                         490
                  ....*....|....*..
gi 497367283  516 QRLKGAFDPHNQLNPGK 532
Cdd:PRK11230  454 HAVKAAFDPDGLLNPGK 470
glpC PRK11168
anaerobic glycerol-3-phosphate dehydrogenase subunit C;
656-999 7.67e-21

anaerobic glycerol-3-phosphate dehydrogenase subunit C;


Pssm-ID: 236869 [Multi-domain]  Cd Length: 396  Bit Score: 96.09  E-value: 7.67e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  656 HEVYDAMAGCLACKSCAGQCPIKVNVPDFRSRFLELYHGRYQRPLRDYLIGSLEFTIPYLAHAPGLYNAVMGSKWVsRLL 735
Cdd:PRK11168   47 ALYDESLKYCSNCKRCEVACPSGVKIGDIIQRARAKYVTERGPPLRDRILSHTDLMGSLATPFAPLVNAATGLKPV-RWL 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  736 AEKVGMVDS--PLiSRFNFQATLTRCRVGVATVPalreltpaQRERSIVLVQDAFTRYFETPLLSAFIDLANRLGHRVFL 813
Cdd:PRK11168  126 LEKTLGIDHrrPL-PKYAFGTFRRWYRKQAAQQA--------QYKKQVAYFHGCYVNYNHPQLGKDLVKVLNAMGYEVLL 196

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  814 APYSANGKPLHVQGFLGAFAKAAIRNASQLKALADCGVPLVGLDPAMTLVYRQEYQKVPGMDG---CPQVLLPQEWLMNV 890
Cdd:PRK11168  197 PKEKCCGLPLIANGFLDKARKQAEFNVESLREAIEKGIPVIATSSSCTLTLRDEYPELLGVDNagvRDHIEDATEFLRRL 276

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  891 L--PEQAPTAPGNFRLMAH--C-TEKTnvpASTRQWEQVFARL-GLKLVTEATGCCGMSGTYGHEARNQETSRTI----F 960
Cdd:PRK11168  277 LdqGKLLPLKPLPLKVAYHtpChLEKQ---GWGLYTLELLRLIpGLEVVVLDSQCCGIAGTYGFKKEKYETSQAIgaplF 353

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 497367283  961 EQSWATKLD---KEGEplatgySCRSQVKRMTERQMRHPLEV 999
Cdd:PRK11168  354 RQIEESGADlvvTDCE------TCKWQIEMSTGLECEHPITL 389
PLN02465 PLN02465
L-galactono-1,4-lactone dehydrogenase
 61-217 9.69e-09

L-galactono-1,4-lactone dehydrogenase


Pssm-ID: 215258 [Multi-domain]  Cd Length: 573  Bit Score: 59.09  E-value: 9.69e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   61 DDVARVATLMAEARFRHVKLTPRGGGTGTNGQSLTDGIVVDLSrHMNNILEINVEERWVRVQAGTVKDQLNAALKPYGLF 140
Cdd:PLN02465  104 ESLEELEDIVKEAHEKGRRIRPVGSGLSPNGLAFSREGMVNLA-LMDKVLEVDKEKKRVTVQAGARVQQVVEALRPHGLT 182

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  141 FaPELSTSNRATVGGMINTDASGQGSctygktrdhvlelhsvllggeRLHslPIDEAALEQACAAPGR---------VGE 211
Cdd:PLN02465  183 L-QNYASIREQQIGGFIQVGAHGTGA---------------------RIP--PIDEQVVSMKLVTPAKgtielskedDPE 238


                  ....*.
gi 497367283  212 VYRMAR 217
Cdd:PLN02465  239 LFRLAR 244
GLDHase TIGR01676
galactonolactone dehydrogenase; This model represents L-Galactono-gamma-lactone dehydrogenase ...
 52-166 2.77e-07

galactonolactone dehydrogenase; This model represents L-Galactono-gamma-lactone dehydrogenase (EC 1.3.2.3). This enzyme catalyzes the final step in ascorbic acid biosynthesis in higher plants. This protein is homologous to ascorbic acid biosynthesis enzymes of other species: L-gulono-gamma-lactone oxidase in rat and L-galactono-gamma-lactone oxidase in yeast. All three covalently bind the cofactor FAD.


Pssm-ID: 130737 [Multi-domain]  Cd Length: 541  Bit Score: 54.30  E-value: 2.77e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283    52 QAAVFpLDADDVARVATLMAEARFRHVKLTPRGGGTGTNGQSLTDGIVVDLSRhMNNILEINVEERWVRVQAGTVKDQLN 131
Cdd:TIGR01676   61 LTRTF-HQPEAIEELEGIVKQANEKKARIRPVGSGLSPNGIGLSRAGMVNLAL-MDKVLEVDEEKKRVRVQAGIRVQQLV 138

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 497367283   132 AALKPYGLFFApELSTSNRATVGGMINTDASGQGS 166
Cdd:TIGR01676  139 DAIKEYGITLQ-NFASIREQQIGGIIQVGAHGTGA 172
PLN02441 PLN02441
cytokinin dehydrogenase
 28-164 7.96e-07

cytokinin dehydrogenase


Pssm-ID: 215242 [Multi-domain]  Cd Length: 525  Bit Score: 52.99  E-value: 7.96e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   28 GQISADYATRTVLATD-NSIYQRLPQAAVFPLDADDVARvatLMAEARFRHVKLT--PRGGGTGTNGQSLT-DGIVVD-- 101
Cdd:PLN02441   41 GHLSFDPVSTASASKDfGNLVHSLPAAVLYPSSVEDIAS---LVRAAYGSSSPLTvaARGHGHSLNGQAQApGGVVVDmr 117

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 497367283  102 -LSRHMNNILEINV--EERWVRVQAGTV-KDQLNAALKpYGLffAPELSTSN-RATVGGMI-NTDASGQ 164
Cdd:PLN02441  118 sLRGGVRGPPVIVVsgDGPYVDVSGGELwIDVLKATLK-HGL--APRSWTDYlYLTVGGTLsNAGISGQ 183
FAD_lactone_ox TIGR01678
sugar 1,4-lactone oxidases; This model represents a family of at least two different sugar 1,4 ...
 63-182 8.30e-04

sugar 1,4-lactone oxidases; This model represents a family of at least two different sugar 1,4 lactone oxidases, both involved in synthesizing ascorbic acid or a derivative. These include L-gulonolactone oxidase (EC 1.1.3.8) from rat and D-arabinono-1,4-lactone oxidase (EC 1.1.3.37) from Saccharomyces cerevisiae. Members are proposed to have the cofactor FAD covalently bound at a site specified by Prosite motif PS00862; OX2_COVAL_FAD; 1.


Pssm-ID: 273751 [Multi-domain]  Cd Length: 438  Bit Score: 42.96  E-value: 8.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283    63 VARVATLMAEARFRHVKLTPRGGGTGTNGQSLTDGIVVDLSRhMNNILEINVEERWVRVQAGTVKDQLNAALKPYGLFFa 142
Cdd:TIGR01678   24 VEEVREVLALAREQKKKVKVVGGGHSPSDIACTDGFLIHLDK-MNKVLQFDKEKKQITVEAGIRLYQLHEQLDEHGYSM- 101

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|
gi 497367283   143 PELSTSNRATVGGMIntdasgqGSCTYGKTRDHVLELHSV 182
Cdd:TIGR01678  102 SNLGSISEVSVAGII-------STGTHGSSIKHGILATQV 134
glcE PRK11282
glycolate oxidase FAD binding subunit; Provisional
 61-280 6.30e-03

glycolate oxidase FAD binding subunit; Provisional


Pssm-ID: 236893 [Multi-domain]  Cd Length: 352  Bit Score: 39.82  E-value: 6.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283   61 DDVARVATLMAEARFRHVKLTPRGGGTGT-NGQSLtDGIVVDLSRHmNNILEINVEERWVRVQAGTVKDQLNAALKPYGL 139
Cdd:PRK11282    2 DISAALLERVRQAAADGTPLRIRGGGSKDfYGRAL-AGEVLDTRAH-RGIVSYDPTELVITARAGTPLAELEAALAEAGQ 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 497367283  140 FFA---PELSTsnRATVGGMINTDASGQGSCTYGKTRDHVLelhsvllgGERLhslpIDeaaleqacaapGRvGEVYRMA 216
Cdd:PRK11282   80 MLPfepPHFGG--GATLGGMVAAGLSGPRRPWAGAVRDFVL--------GTRL----IN-----------GR-GEHLRFG 133

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 497367283  217 rdiqqtqGDLIERtfpklnrcLTGYDLAHLrdeqgrfnlnsvLCGAEGSLGYVVEAKLNVLPIP 280
Cdd:PRK11282  134 -------GQVMKN--------VAGYDVSRL------------MAGSLGTLGVLLEVSLKVLPRP 170
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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