|
Name |
Accession |
Description |
Interval |
E-value |
| YidC |
COG0706 |
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis]; |
85-324 |
1.47e-43 |
|
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440470 [Multi-domain] Cd Length: 212 Bit Score: 148.73 E-value: 1.47e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 85 MDEGWFhGIIVYPIAQLINWVANFT-DAGIGIIAATFLIQLLIFLFSIKSQVANQRMQALQPEMQKIQAKYAGrtddrSK 163
Cdd:COG0706 1 IDYGWF-GFIAKPLFWLLNFLHSLVgNWGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYKD-----DP 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 164 MAQAQEMQALYSKYKINPFGTLLITFIQFPVILGMYQATMRAYSVVTGSFAGINLaktpiegLKEGQIAFGVIFILMVLF 243
Cdd:COG0706 75 QKLQQEMMKLYKEEGVNPLGGCLPMLIQMPIFIALYRVLRNSIELRHAPFLGIPD-------LSAPDPYYIFLPILMGVT 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 244 QLLSFKMPQwlqehrkkkqhvkekkyaepkkQPGMMGSMNMMMYMSTAMIAIFAINWPLGMSFYWLVNSIVRVGQNLLIH 323
Cdd:COG0706 148 MFLQQKLNP----------------------APAQDPQQKKMMYIMPLMFLFFFLSFPAGLVLYWVVSNLLTIGQQLIIN 205
|
.
gi 495965667 324 K 324
Cdd:COG0706 206 R 206
|
|
| 5TM_YidC_Alb3 |
cd20070 |
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ... |
112-324 |
6.11e-38 |
|
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410994 [Multi-domain] Cd Length: 181 Bit Score: 133.27 E-value: 6.11e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 112 GIGIIAATFLIQLLIFLFSIKSQVANQRMQALQPEMQKIQAKYAgrtDDrsKMAQAQEMQALYSKYKINPFGTLLITFIQ 191
Cdd:cd20070 1 GLAIILLTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYK---DD--KQKLQQEMMKLYKEHGVNPLGGCLPLLIQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 192 FPVILGMYQATMRAYSVVTGSFAG--INLAKTPIeglkegqiaFGVIFILMVLFQLLSFKMPqwlqehrkkkqhvkekky 269
Cdd:cd20070 76 MPIFIALYQVLRNSIELRGAPFLWwiLDLSAPDP---------YYILPILMGVTMFLQQKLT------------------ 128
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 495965667 270 aePKKQPGMMGSMNMMMYMSTAMIAIFAINWPLGMSFYWLVNSIVRVGQNLLIHK 324
Cdd:cd20070 129 --PTPTDDQAPQQKMMMYFMPVMFTFIFLSFPSGLVLYWLVSNLFSIIQQLIINK 181
|
|
| 60KD_IMP |
pfam02096 |
60Kd inner membrane protein; |
112-324 |
6.08e-37 |
|
60Kd inner membrane protein;
Pssm-ID: 460443 [Multi-domain] Cd Length: 187 Bit Score: 130.67 E-value: 6.08e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 112 GIGIIAATFLIQLLIFLFSIKSQVANQRMQALQPEMQKIQAKYAgrtDDRskMAQAQEMQALYSKYKINPFGTLLITFIQ 191
Cdd:pfam02096 2 GLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYK---DDR--QKLQQEMMKLYKKEGVNPLGGCLPMLIQ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 192 FPVILGMYQATMRAYSVVTGSFAG--INLAKTPieglKEGQIAFGVIFILMVLFQLLSFKMpqwlqehrkkkqhvkekky 269
Cdd:pfam02096 77 MPIFIALYRVLRNSIELRHAPFFLwiADLSAPD----PISILHYYILPILMGVTMFLQQKL------------------- 133
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 495965667 270 aEPKKQPGMMGSMNMMMYMSTAMIAIFAINWPLGMSFYWLVNSIVRVGQNLLIHK 324
Cdd:pfam02096 134 -TPAPQDQPPQMKMMMLYFMPLMFLFFFLNFPAGLVLYWVVSNLLSIGQQLIINR 187
|
|
| PRK02201 |
PRK02201 |
putative inner membrane protein translocase component YidC; Provisional |
88-324 |
9.21e-35 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235012 Cd Length: 357 Bit Score: 129.75 E-value: 9.21e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 88 GWFHGIIVYPIAQLINWVANF----TDAGIGIIAA----TFLIQLLIFLFSIKSQVANQRMQALQPEMQKIQAKYAG-RT 158
Cdd:PRK02201 102 GPFYGLFVYPIAQIILSIMASqslsELYGWSTILAiivvVLIIRLISFLITFKSTFNQEKQEELQGKKAKIDAKYKDyKK 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 159 DDRSKMAQAQEMQALYSKYKINPFGTLLITFIQFPVILGMYQATMRAYSVVTGSFAGINLAKTPIEGLKEGQIAFGVIFI 238
Cdd:PRK02201 182 DKQMKQRKQQEIQELYKKHNISPFSPFVQMFVTLPIFIAVYRVVQSLPSIKVTTWLGIDLSATSWQEIFAGNWIYLPILI 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 239 LMVLFQLLSFKMPQWLQEHRKKKQHVKEKKYAEPKKQpgmmgsmNMMMYMSTAMIAIFAINWPLGMSFYWLVNSIVRVGQ 318
Cdd:PRK02201 262 IVVPVQALSQLLPQILNKKKNKERTLNVKEKEALKKQ-------NKTQNIISIVFIFFGVIFAAGVQIYWIIGGIWTILQ 334
|
....*.
gi 495965667 319 NLLIHK 324
Cdd:PRK02201 335 TLGIHY 340
|
|
| yidC_oxa1_cterm |
TIGR03592 |
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ... |
112-322 |
5.13e-33 |
|
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274665 [Multi-domain] Cd Length: 179 Bit Score: 120.28 E-value: 5.13e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 112 GIGIIAATFLIQLLIFLFSIKSQVANQRMQALQPEMQKIQAKYAGrtddrSKMAQAQEMQALYSKYKINPFGTLLITFIQ 191
Cdd:TIGR03592 3 GLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYKE-----DPQKLQQEMMKLYKEEGVNPLGGCLPLLIQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 192 FPVILGMYQATMRAYSVVTGSFAGI-NLAKtpieglkegQIAFGVIFILMVLFQLLSFKMpqwlqehrkkkqhvKEKKYA 270
Cdd:TIGR03592 78 MPIFIALYQVLLRSIELRHAPFLWIiDLSS---------PDPYYILPILMGVTMFLQQKL--------------SPKGPP 134
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 495965667 271 EPKKQpgmmgsmNMMMYMSTAMIAIFAINWPLGMSFYWLVNSIVRVGQNLLI 322
Cdd:TIGR03592 135 DPAQQ-------KMMMYFMPLMFLFFFLSFPAGLVLYWVVSNLFTIIQQLII 179
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| YidC |
COG0706 |
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis]; |
85-324 |
1.47e-43 |
|
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440470 [Multi-domain] Cd Length: 212 Bit Score: 148.73 E-value: 1.47e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 85 MDEGWFhGIIVYPIAQLINWVANFT-DAGIGIIAATFLIQLLIFLFSIKSQVANQRMQALQPEMQKIQAKYAGrtddrSK 163
Cdd:COG0706 1 IDYGWF-GFIAKPLFWLLNFLHSLVgNWGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYKD-----DP 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 164 MAQAQEMQALYSKYKINPFGTLLITFIQFPVILGMYQATMRAYSVVTGSFAGINLaktpiegLKEGQIAFGVIFILMVLF 243
Cdd:COG0706 75 QKLQQEMMKLYKEEGVNPLGGCLPMLIQMPIFIALYRVLRNSIELRHAPFLGIPD-------LSAPDPYYIFLPILMGVT 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 244 QLLSFKMPQwlqehrkkkqhvkekkyaepkkQPGMMGSMNMMMYMSTAMIAIFAINWPLGMSFYWLVNSIVRVGQNLLIH 323
Cdd:COG0706 148 MFLQQKLNP----------------------APAQDPQQKKMMYIMPLMFLFFFLSFPAGLVLYWVVSNLLTIGQQLIIN 205
|
.
gi 495965667 324 K 324
Cdd:COG0706 206 R 206
|
|
| 5TM_YidC_Alb3 |
cd20070 |
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ... |
112-324 |
6.11e-38 |
|
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410994 [Multi-domain] Cd Length: 181 Bit Score: 133.27 E-value: 6.11e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 112 GIGIIAATFLIQLLIFLFSIKSQVANQRMQALQPEMQKIQAKYAgrtDDrsKMAQAQEMQALYSKYKINPFGTLLITFIQ 191
Cdd:cd20070 1 GLAIILLTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYK---DD--KQKLQQEMMKLYKEHGVNPLGGCLPLLIQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 192 FPVILGMYQATMRAYSVVTGSFAG--INLAKTPIeglkegqiaFGVIFILMVLFQLLSFKMPqwlqehrkkkqhvkekky 269
Cdd:cd20070 76 MPIFIALYQVLRNSIELRGAPFLWwiLDLSAPDP---------YYILPILMGVTMFLQQKLT------------------ 128
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 495965667 270 aePKKQPGMMGSMNMMMYMSTAMIAIFAINWPLGMSFYWLVNSIVRVGQNLLIHK 324
Cdd:cd20070 129 --PTPTDDQAPQQKMMMYFMPVMFTFIFLSFPSGLVLYWLVSNLFSIIQQLIINK 181
|
|
| 60KD_IMP |
pfam02096 |
60Kd inner membrane protein; |
112-324 |
6.08e-37 |
|
60Kd inner membrane protein;
Pssm-ID: 460443 [Multi-domain] Cd Length: 187 Bit Score: 130.67 E-value: 6.08e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 112 GIGIIAATFLIQLLIFLFSIKSQVANQRMQALQPEMQKIQAKYAgrtDDRskMAQAQEMQALYSKYKINPFGTLLITFIQ 191
Cdd:pfam02096 2 GLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYK---DDR--QKLQQEMMKLYKKEGVNPLGGCLPMLIQ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 192 FPVILGMYQATMRAYSVVTGSFAG--INLAKTPieglKEGQIAFGVIFILMVLFQLLSFKMpqwlqehrkkkqhvkekky 269
Cdd:pfam02096 77 MPIFIALYRVLRNSIELRHAPFFLwiADLSAPD----PISILHYYILPILMGVTMFLQQKL------------------- 133
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 495965667 270 aEPKKQPGMMGSMNMMMYMSTAMIAIFAINWPLGMSFYWLVNSIVRVGQNLLIHK 324
Cdd:pfam02096 134 -TPAPQDQPPQMKMMMLYFMPLMFLFFFLNFPAGLVLYWVVSNLLSIGQQLIINR 187
|
|
| PRK02201 |
PRK02201 |
putative inner membrane protein translocase component YidC; Provisional |
88-324 |
9.21e-35 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235012 Cd Length: 357 Bit Score: 129.75 E-value: 9.21e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 88 GWFHGIIVYPIAQLINWVANF----TDAGIGIIAA----TFLIQLLIFLFSIKSQVANQRMQALQPEMQKIQAKYAG-RT 158
Cdd:PRK02201 102 GPFYGLFVYPIAQIILSIMASqslsELYGWSTILAiivvVLIIRLISFLITFKSTFNQEKQEELQGKKAKIDAKYKDyKK 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 159 DDRSKMAQAQEMQALYSKYKINPFGTLLITFIQFPVILGMYQATMRAYSVVTGSFAGINLAKTPIEGLKEGQIAFGVIFI 238
Cdd:PRK02201 182 DKQMKQRKQQEIQELYKKHNISPFSPFVQMFVTLPIFIAVYRVVQSLPSIKVTTWLGIDLSATSWQEIFAGNWIYLPILI 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 239 LMVLFQLLSFKMPQWLQEHRKKKQHVKEKKYAEPKKQpgmmgsmNMMMYMSTAMIAIFAINWPLGMSFYWLVNSIVRVGQ 318
Cdd:PRK02201 262 IVVPVQALSQLLPQILNKKKNKERTLNVKEKEALKKQ-------NKTQNIISIVFIFFGVIFAAGVQIYWIIGGIWTILQ 334
|
....*.
gi 495965667 319 NLLIHK 324
Cdd:PRK02201 335 TLGIHY 340
|
|
| yidC_oxa1_cterm |
TIGR03592 |
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ... |
112-322 |
5.13e-33 |
|
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274665 [Multi-domain] Cd Length: 179 Bit Score: 120.28 E-value: 5.13e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 112 GIGIIAATFLIQLLIFLFSIKSQVANQRMQALQPEMQKIQAKYAGrtddrSKMAQAQEMQALYSKYKINPFGTLLITFIQ 191
Cdd:TIGR03592 3 GLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYKE-----DPQKLQQEMMKLYKEEGVNPLGGCLPLLIQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 192 FPVILGMYQATMRAYSVVTGSFAGI-NLAKtpieglkegQIAFGVIFILMVLFQLLSFKMpqwlqehrkkkqhvKEKKYA 270
Cdd:TIGR03592 78 MPIFIALYQVLLRSIELRHAPFLWIiDLSS---------PDPYYILPILMGVTMFLQQKL--------------SPKGPP 134
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 495965667 271 EPKKQpgmmgsmNMMMYMSTAMIAIFAINWPLGMSFYWLVNSIVRVGQNLLI 322
Cdd:TIGR03592 135 DPAQQ-------KMMMYFMPLMFLFFFLSFPAGLVLYWVVSNLFTIIQQLII 179
|
|
| PRK02944 |
PRK02944 |
YidC family membrane integrase SpoIIIJ; |
87-322 |
2.47e-26 |
|
YidC family membrane integrase SpoIIIJ;
Pssm-ID: 179508 Cd Length: 255 Bit Score: 104.85 E-value: 2.47e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 87 EGWFHGIIVYPIAQLINWVANFTDA--GIGIIAATFLIQLLIFLFSIKSQVANQRMQALQPEMQKIQAKYAGRtDDRSKM 164
Cdd:PRK02944 33 TGFWNEYFVYPLSQLITYFANLFGSnyGLAIIVVTLLIRLLILPLMIKQTKSTKAMQALQPEMQKLKEKYSSK-DQATQQ 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 165 AQAQEMQALYSKYKINPFGTLLITFIQFPVILGMYQATMRAYSVVTGSFAGINL-AKTPieglkegqiafgvIFILMVLF 243
Cdd:PRK02944 112 KLQQEMMQLFQKNGVNPLAGCLPIFIQMPILIAFYHAIMRTSEISKHSFLWFDLgQADP-------------YYILPIVA 178
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 495965667 244 QLLSFkmpqwLQEhrkkkqhvKEKKYAEPKKQPgmmgSMNMMMYMSTAMIAIFAINWPLGMSFYWLVNSIVRVGQNLLI 322
Cdd:PRK02944 179 GITTF-----IQQ--------KLMMAGTAGQNP----QMAMMLWLMPIMILIFAINFPAALSLYWVVGNIFMIAQTYLI 240
|
|
| PRK01622 |
PRK01622 |
membrane protein insertase YidC; |
83-324 |
6.26e-24 |
|
membrane protein insertase YidC;
Pssm-ID: 179310 Cd Length: 256 Bit Score: 98.29 E-value: 6.26e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 83 DAMDEGWFHGIIVYPIAQLINWVANFTDA--GIGIIAATFLIQLLIF-LF--SIKSQVANQ-RMQALQPEMQKIQAKYAg 156
Cdd:PRK01622 30 DAHSDGFFDHYFVYPFSFLIQFVAHHIGGsyGIAIIIVTLIIRSLMIpLAvsQYKSQRGMQeKMAVMKPELDKIQAKLK- 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 157 RTDDRSKMAQAQ-EMQALYSKYKINPFGT-LLITFIQFPVILGMYQATMRAYSVVTGSFAGINLAKTPIeglkegqiafg 234
Cdd:PRK01622 109 VTKDLEKQKEYQkEMMELYKSGNINPLAMgCLPLLIQMPILSAFYYAIRRTEEIASHSFLWFNLGHADH----------- 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 235 VIFILMVLFQLLSFKMPQWLQEHRKKKQHVKEKKYAEPkkqpgmmgsmnmmmymstAMIAIFAINWPLGMSFYWLVNSIV 314
Cdd:PRK01622 178 ILPIIAGLTYFIQMKVSQSNGTSPEQVQMLKIQGIMMP------------------AMILFMSFAAPSALVLYWITGGLF 239
|
250
....*....|
gi 495965667 315 RVGQNLLIHK 324
Cdd:PRK01622 240 LMGQTIVLRK 249
|
|
| PRK01318 |
PRK01318 |
membrane protein insertase; Provisional |
81-200 |
3.26e-23 |
|
membrane protein insertase; Provisional
Pssm-ID: 234942 [Multi-domain] Cd Length: 521 Bit Score: 99.95 E-value: 3.26e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 81 FSDAMDEGWFHgIIVYPIAQLINW----VANFtdaGIGIIAATFLIQLLIFLFSIKSQVANQRMQALQPEMQKIQAKYAg 156
Cdd:PRK01318 293 LDLAVDYGWLW-FITKPLFWLLDFlhsfVGNW---GWAIILLTIIVKLLLFPLTYKSYVSMAKMKVLQPKMQELKEKYK- 367
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 495965667 157 rtDDRSKMaqAQEMQALYSKYKINPFGTLLITFIQFPVILGMYQ 200
Cdd:PRK01318 368 --DDPQKM--QQEMMELYKKEKVNPLGGCLPILIQIPIFFALYK 407
|
|
| 5TM_Oxa1-like |
cd20069 |
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar ... |
115-321 |
1.81e-21 |
|
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar proteins; This group is composed mostly of the mitochondrial members of the YidC/Oxa1/Alb3 protein family of insertases, including mitochondrial inner membrane proteins Oxa1, Oxa1-like (Oxa1L), cytochrome c oxidase assembly protein 18 (Cox18, also called Oxa2), and Arabidopsis thaliana mitochondrial ALBINO3-like protein 3 (ALB33). It also includes Arabidopsis thaliana chloroplastic ALBINO3-like protein 2 (ALB32). Members of this group mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Oxa1 and Cox18/Oxa2 are essential for the activity and assembly of cytochrome c oxidase, playing central roles in the translocation and export of the N-terminal and C-terminal parts, respectively, of the COX2 protein into the mitochondrial intermembrane space. ALB32 may be involved in the insertion of integral membrane proteins into the chloroplast thylakoid membranes. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410993 [Multi-domain] Cd Length: 201 Bit Score: 90.27 E-value: 1.81e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 115 IIAATFLIQLLIFLFSIKSQVANQRMQALQPEMQKIQAK--YAGRTDDRSKMAQA-QEMQALYSKYKINPFGTLLITFIQ 191
Cdd:cd20069 8 IAATTVALRLLLLPLVIKSQRNAARMANLQPELQKLQEKlkEARASGDQLEAAEArKELKELMKKHNVNPLKSLLLPLVQ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 192 FPVILGMYQAtMRaysvvtgsfagiNLAKTPIEGLKEGQIA----------FGVIFILMVLFQLLSFKMpqwlqehrkkk 261
Cdd:cd20069 88 APVFISFFFA-LR------------KMANLPVPSFKTGGLLwftdltvpdpYYILPILTSLTFLATIEL----------- 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 495965667 262 qhvkekkYAEPKKQPGMMGSMNMMMYMSTAMIAI-FAINWPLGMSFYWLVNSIVRVGQNLL 321
Cdd:cd20069 144 -------GAETGTSGSPQSKTMKNVFRGLPVLMIpFTANFPSAVFLYWITSNLFSLAQNLL 197
|
|
| PRK00145 |
PRK00145 |
putative inner membrane protein translocase component YidC; Provisional |
112-324 |
1.89e-18 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234665 [Multi-domain] Cd Length: 223 Bit Score: 82.48 E-value: 1.89e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 112 GIGIIAATFLIQLLIFLFSIKSQVANQRMQALQPEMQKIQAKYagrTDDRSKmaQAQEMQALYSKYKINPFGTLLITFIQ 191
Cdd:PRK00145 32 GIAIILVTLIIRLLILPLNIKQTKSSLRMNEIQPEIKKLQAKY---KNDPQK--LQQEMMKLYKEKGVNPLGGCLPLLIQ 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 192 FPVILGMYQATMRAYSVVTGSFAGI-NLAKTPIEglkegqiafgviFILMVLFQLLSFkmpqwlqehrkkkqhvkEKKYA 270
Cdd:PRK00145 107 WPILIALYYVFNNLTGINGVSFLWIkDLAKPDIT------------WILPILSGATTY-----------------LSGYL 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 495965667 271 EPKKQPGMMGSMNMMMYMSTAMIAIFAINWPLGMSFYWLVNSIVRVGQNLLIHK 324
Cdd:PRK00145 158 MTKADSSQAGQMKTMNIGMSIFMGVMSWKFKSALVLYWVIGNLIQIIQTYFIKK 211
|
|
| 5TM_YidC_Oxa1_Alb3 |
cd19751 |
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1 ... |
112-324 |
1.16e-17 |
|
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1/Alb3 protein family of insertases facilitate the insertion, folding and assembly of proteins of the inner membranes of bacteria and mitochondria, and the thylakoid membrane of plastids. Members include bacterial YidC, mitochondrial Cox18 and Oxa1, and chloroplastic Alb3 and Alb4. Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Oxa1 and Cox18/Oxa2 mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Alb3 and Alb3-like proteins, including Alb4, are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410992 [Multi-domain] Cd Length: 189 Bit Score: 79.52 E-value: 1.16e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 112 GIGIIAATFLIQLLIFLFSIKSQVANQRMQALQPEMQKIQAKYAGRTDDRSKMAQAQ-EMQALYSKYKINPFGTLLITFI 190
Cdd:cd19751 1 GLSIIIVTILIRLALLPLTLKQQKSMRKMQVIRPEMEAIREKYKEKASKDKVQQEMQkEMLGLYKKHGVNPMAGCLPLFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 191 QFPVILGMYQATMRAYSVVTGSFAGINLAKTPieglkegqIAFGVIFILMVLFQLLSFKM-PQWLQEHRKKKQHVKEKKY 269
Cdd:cd19751 81 QLPIFMAFYFAIMRTEEIRYHTFLWFFDLGQP--------DYLYILPFVAGITTYFQFKMtMSHQQQMQMMQMQMKVMLY 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 495965667 270 AEPkkqpgmmgsmnmmmymstAMIAIFAINWPLGMSFYWLVNSIVRVGQNLLIHK 324
Cdd:cd19751 153 VMP------------------VMIIIAGLSFPSALSLYWIISNLFMIIQTYFIVR 189
|
|
| PRK01315 |
PRK01315 |
putative inner membrane protein translocase component YidC; Provisional |
112-322 |
3.84e-15 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234941 Cd Length: 329 Bit Score: 74.77 E-value: 3.84e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 112 GIGIIAATFLIQLL---IFLFSIKSQvanQRMQALQPEMQKIQAKYAGrtdDRSKMAQaqEMQALYSKYKINPFGTLLIT 188
Cdd:PRK01315 43 VLSIVGLVIVIRALlipLFVKQIKSQ---RNMQEIQPKMKKIQEKYKG---DRERMSQ--EMMKLYKETGTNPLSSCLPL 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 189 FIQFPVILGMYQATMRAYSVVTG---------------SFAGINLAKTPIEGLKEGQIAFGVIFILMVLF---------- 243
Cdd:PRK01315 115 LLQMPIFFALYRVLDSAASRGDGigpinppllesfrhaHIFGAPLAATFLQALNAGNTAVQVVAAVLIILmsasqfitql 194
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 495965667 244 QLLSFKMPQwlqehrkkkqhvkekkyaEPKKQPGMMGSMNMMMYMsTAMIAIFAINWPLGMSFYWLVNSIVRVGQNLLI 322
Cdd:PRK01315 195 QLMTKNMPP------------------EAKTGPMAQQQKMLLYLF-PLMFLVSGIAFPVGVLFYWLTSNVWTMGQQFYV 254
|
|
| PRK02463 |
PRK02463 |
OxaA-like protein precursor; Provisional |
87-322 |
6.86e-15 |
|
OxaA-like protein precursor; Provisional
Pssm-ID: 235040 Cd Length: 307 Bit Score: 74.00 E-value: 6.86e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 87 EGWFHGIIVYPIAQLINWVANFTDAGIG--IIAATFLIQLLIFLFSI----KSQVANQRMQALQPEMQKIQAKYAGRTDD 160
Cdd:PRK02463 34 TGFIWNFLGAPMSYFIDYFANNLGLGFGlaIIIVTIIVRLIILPLGLyqswKATYQSEKMAYLKPVFEPINERLKNATTQ 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 161 RSKMAQAQEMQALYSKYKINPFGTL--LITFIQFPVILGMYQATMRAYSVVTGSFAGINLaktpieglkeGQIAFGVIFI 238
Cdd:PRK02463 114 EEKMAAQTELMAAQRENGISMLGGIgcLPLLIQMPFFSALYFAAQYTKGVSTSTFLGIDL----------GSPSLVLTAI 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 239 LMVLFQLLSfkmpqWLQEHRKKKqhvkekkyaEPKKQpgmmgsMNMMMYMSTAMIAIFAINWPLGMSFYWLVNSIVRVGQ 318
Cdd:PRK02463 184 IGVLYFFQS-----WLSMMGVPE---------EQREQ------MKAMMYMMPIMMVVFSFSSPAGVGLYWLVGGFFSIIQ 243
|
....
gi 495965667 319 NLLI 322
Cdd:PRK02463 244 QLIT 247
|
|
| PRK03449 |
PRK03449 |
putative inner membrane protein translocase component YidC; Provisional |
93-199 |
1.22e-11 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 179580 Cd Length: 304 Bit Score: 64.32 E-value: 1.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 93 IIVYPIAQlINWV-----------ANFTDAGIGIIAATFLIQLLIFLFSIKSQVANQRMQALQPEMQKIQAKYAGrtdDR 161
Cdd:PRK03449 4 FIYYPVSA-ILWFwhklfsfvlgpDNGFAWALSVMFLVFTLRALLYKPFVRQIRTTRKMQELQPQIKALQKKYGN---DR 79
|
90 100 110
....*....|....*....|....*....|....*...
gi 495965667 162 SKMAQaqEMQALYSKYKINPFGTLLITFIQFPVILGMY 199
Cdd:PRK03449 80 QKMAL--EMQKLQKEHGFNPILGCLPMLAQIPVFLGLF 115
|
|
| PRK01001 |
PRK01001 |
putative inner membrane protein translocase component YidC; Provisional |
88-199 |
6.14e-10 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234887 [Multi-domain] Cd Length: 795 Bit Score: 60.20 E-value: 6.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 88 GWFhGIIVYPIAQLINWVANF----TDA-GIGIIAATFLIQLLIF---LFSIKSQVanqRMQALQPEMQKIQAKYAgRTD 159
Cdd:PRK01001 549 GFF-SFITEPFAALLFIIMKFfkflTGSwGISIILLTVFLKLLLYplnAWSIRSMR---RMQKLSPYIQEIQQKYK-KEP 623
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 495965667 160 DRSKMaqaqEMQALYSKYKINPFGTLLITFIQFPVILGMY 199
Cdd:PRK01001 624 KRAQM----EIMALYKTNKVNPITGCLPLLIQLPFLIAMF 659
|
|
| PRK02654 |
PRK02654 |
putative inner membrane protein translocase component YidC; Provisional |
112-217 |
3.54e-09 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235058 Cd Length: 375 Bit Score: 57.30 E-value: 3.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 112 GIGIIAATFLIQLLIFLFSIKSQVANQRMQALQPEMQK----IQAKYAgrtDDRSKmaQAQEMQALYSKYKiNPFGTLLI 187
Cdd:PRK02654 28 GLAIVALTLVIRFALYPLSAGSIRNMRRMKIAQPVMQKrqaeIQERYK---NDPQK--QQEEMGKLMKEFG-NPLAGCLP 101
|
90 100 110
....*....|....*....|....*....|.
gi 495965667 188 TFIQFPVILGMYqATMRaysvvtGS-FAGIN 217
Cdd:PRK02654 102 LLVQMPILFALF-ATLR------GSpFADVN 125
|
|
| PRK00247 |
PRK00247 |
putative inner membrane protein translocase component YidC; Validated |
93-204 |
7.89e-09 |
|
putative inner membrane protein translocase component YidC; Validated
Pssm-ID: 178945 [Multi-domain] Cd Length: 429 Bit Score: 56.40 E-value: 7.89e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 495965667 93 IIVYPIAQLIN-WVANFTDA-GIGIIAATFL--------IQLLIFLFSIKsQVANQRMQA-LQPEMQKIQAKYAGRTDDR 161
Cdd:PRK00247 4 IFIYPVSGVMKlWHLLLHNVlGLDDSLAWFAslfglvitVRAIIAPFTWQ-QYKSGRTAAhIRPKRKALREEYKGKTDEA 82
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 495965667 162 SKMAQAQEMQALYSKYKINPFGTLLITFIQFPVILGMYQATMR 204
Cdd:PRK00247 83 SIRELQQKQKDLNKEYGYNPLAGCVPALIQIPVFLGLYQVLLR 125
|
|
| |
