|
Name |
Accession |
Description |
Interval |
E-value |
| PRK03818 |
PRK03818 |
putative transporter; Validated |
10-553 |
0e+00 |
|
putative transporter; Validated
Pssm-ID: 179654 [Multi-domain] Cd Length: 552 Bit Score: 798.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 10 EHSALQAVVVLSLISAIGLGLGKIHVCGISLGVTFVFFAGIIAGHF----GLSIDPQMLNYAESFGLVIFVYALGLQVGP 85
Cdd:PRK03818 1 MSDIALTVSILALVAVVGLWIGNIKIRGVGLGIGGVLFGGIIVGHFvsqfGLTLDSDMLHFIQEFGLILFVYTIGIQVGP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 86 GFFSSFRKGGVQLNMLATGVVLIGTLLTVLGSYGLGVSLPDMVGILCGATTNTPALGAAQQTLKQMGLESS---TPALGC 162
Cdd:PRK03818 81 GFFSSLRKSGLRLNLFAVLIVILGGLVTAILHKLFGIPLPVMLGIFSGAVTNTPALGAGQQILRDLGTPGDlvdQMGMGY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 163 AVAYPLGVVGVILAVLFIRKTLAHKEDLELKEKDDV-----NKPYIVAFQVHNPAIFNKSIKEIGGLNsYPKFVISRLWR 237
Cdd:PRK03818 161 AMAYPFGICGILLSMWLIRLIFRINVDKEAQEFESSsgnghELLQTINIRVENPNLHGKAIKDVPILN-GDKFVCSRLKR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 238 DGNVSIPTSEKIIKEGDRLLVITSEKNTPALTVLFGEQEhtdwnkeDIDWNAIDSQLISQRIVVTRPELNGKKLGSLHLR 317
Cdd:PRK03818 240 GDTLMVPSPDTIIQLGDLLHLVGQPEDLHKAQLVIGEEV-------DTSLSTRGTDLRSERVVVTNEKVLGKKLRDLHLK 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 318 NHYGINISRVYRSGVQLLATAELTLQLGDRLTVVGEAAAIQNVEKVLGNAVKSLKEPNLVAVFIGIVIGLALGAIPISIP 397
Cdd:PRK03818 313 NKYGVVISRLNRAGVELVASPDLSLQFGDILNLVGRPEAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPFFIP 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 398 GISAPVRLGLAGGPIIVGILIGTFGPRMHMVTYTTRSANLMLRALGLSLYLACLGLDAGAHFFDTVFRPEGLLWIATGFA 477
Cdd:PRK03818 393 GFPAALKLGLAGGPLIVALILGRIGSIGKLYWFMPPSANLALRELGIVLFLAVVGLKSGGDFVDTLVNGEGLSWIGYGFL 472
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492386624 478 LTVVPVLIMGIVTFKWLKIDFGTMAGMLCGSMANPMALNYANDTIP-GDNPSVAYATVYPLCMFLRVIIAQVLLMFF 553
Cdd:PRK03818 473 ITAVPLLIVGILARMLAKMNYLTLCGMLAGSMTDPPALAFANNLHPtSGAAALSYATVYPLVMFLRIITPQLLAVLF 549
|
|
| YbjL |
COG2985 |
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only]; ... |
8-553 |
0e+00 |
|
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only];
Pssm-ID: 442224 [Multi-domain] Cd Length: 543 Bit Score: 593.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 8 FVEHSALQAVVVLSLISAIGLGLGKIHVCGISLGVTFVFFAGIIAGHFGlsIDPQMLNYAESFGLVIFVYALGLQVGPGF 87
Cdd:COG2985 3 LFELLVANPELALFLVIALGYLLGKIKIGGFSLGVAGVLFVGLLIGHFG--VTLHIPHFVKSLGLALFVYAIGLQVGPGF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 88 FSSFRKGGVQLNMLATGVVLIGTLLTVLGSYGLGVSLPDMVGILCGATTNTPALGAAQQTLKQMGLE---SSTPALGCAV 164
Cdd:COG2985 81 FASLKRDGLKLNLLAVVVVVLGLLVALALAKLFGLDPGLAAGLFAGALTNTPALGAAQDALGKLGLSkqlSANPAVGYAV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 165 AYPLGVVGVILAVLFIRKTLAHK-----EDLELKEKDDVNKPYIVAFQVHNPAIFNKSIKEIGGLNSyPKFVISRLWRDG 239
Cdd:COG2985 161 AYPFGVIGIILFVALLPKLFRIDldaeaKKLEAGEGSAYPPLVTRAYRVTNPNLVGKTVAELEALLG-TRVVISRIRRGG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 240 NVSIPTSEKIIKEGDRLLVITSEKNTPALTVLFGEQEHTDwnkedidwNAIDSQLISQRIVVTRPELNGKKLGSLHLRNH 319
Cdd:COG2985 240 EIIVPTPDTVLQEGDIVLVVGTREALEAAEALLGEEVDDS--------ELLDSDLDVRRIVVTNKEVAGKTLGELNLRNR 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 320 YGINISRVYRSGVQLLATAELTLQLGDRLTVVGEAAAIQNVEKVLGNAVKSLKEPNLVAVFIGIVIGLALGAIPISIPGI 399
Cdd:COG2985 312 FGVVITRVRRGGVELPATPDTVLQLGDRLTVVGPKEDVERVAKLLGNSERKLSETDLLPLGLGIVLGLLLGSIPIPLPGI 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 400 SaPVRLGLAGGPIIVGILIGTFGPRMHMVTYTTRSANLMLRALGLSLYLACLGLDAGAHFFDTVFRpEGLLWIATGFALT 479
Cdd:COG2985 392 P-PLSLGLAGGPLIVGLLLGRLGRTGPLVGYMPPSANLLLRELGLALFLAVVGLSAGPGFVETLQE-SGLLLFLLGALVT 469
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492386624 480 VVPVLIMGIVTFKWLKIDFGTMAGMLCGSMANPMALNYANDTIPGDNPSVAYATVYPLCMFLRVIIAQVLLMFF 553
Cdd:COG2985 470 LVPLLVVLLVGRYVLKLNYLILLGALAGAMTSPPALAAANEAAGSDAPALGYATVYPLAMILLILLGQLLVLLL 543
|
|
| Asp-Al_Ex |
pfam06826 |
Predicted Permease Membrane Region; This family represents five transmembrane helices that are ... |
378-551 |
1.10e-43 |
|
Predicted Permease Membrane Region; This family represents five transmembrane helices that are normally found flanking (five either side) a pair of pfam02080 domains. This suggests that the paired regions form a ten helical structure, probably forming the pore, whereas the pfam02080) binds a ligand for export or regulation of the pore. Swiss:Q8L3K8 is described as a aspartate-alanine antiporter. In conjunction with Swiss:Q8L3K9 it forms a 'proton motive metabolic cycle catalyzed by an aspartate-alanine exchange'. The general conservation of domain architecture in this family suggests that they are functional orthologues.
Pssm-ID: 284291 [Multi-domain] Cd Length: 167 Bit Score: 152.73 E-value: 1.10e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 378 AVFIGIVIGLALGAIPISIPgisapVRLGLAGGPIIVGILIGTFGPRMHmvTYTTRSANLMLRALGLSLYLACLGLDAGA 457
Cdd:pfam06826 1 ALFLGIALGLLLGRIKISGG-----FSLGVAGGVLIVGLLLGHFGSTGP--TFMPISALSFLRELGLALFLAAVGLSAGP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 458 HFFDTVFRPeGLLWIATGFALTVVPVLIMGIVTFKWLKIDFGTMAGMLCGSMANPMALNYANDTIPG-DNPSVAYATVYP 536
Cdd:pfam06826 74 GFFSSLKKD-GLLLIGLALLVTVVPLLLALVLGKYVLKLDPGLLAGLLAGALTSTPALGAANDALAGsDIPALGYAVTYP 152
|
170
....*....|....*
gi 492386624 537 LCMFLRVIIAQVLLM 551
Cdd:pfam06826 153 FGVVGLILAGQVLAK 167
|
|
| YidE_YbjL_dupl |
TIGR01625 |
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is ... |
383-537 |
1.31e-42 |
|
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is duplicated the aspartate-alanine antiporter AspT, as well as HI0035 of Haemophilus influenzae, YidE and YbjL of E. coli, and a number of other known or putative transporters. Member proteins may have 0, 1, or 2 copies of TrkA potassium uptake domain pfam02080 between the duplications. The domain contains several apparent transmembrane regions and is proposed here to act in transport. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 130686 [Multi-domain] Cd Length: 154 Bit Score: 149.40 E-value: 1.31e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 383 IVIGLALGAIPISIPGisAPVRLGLAGGPIIVGILIGTFGPRMHMVTYTTRSANLMLRALGLSLYLACLGLDAGAHFFDT 462
Cdd:TIGR01625 1 LALGLLLGKIPIGLPG--FSIKLGNAGGVLFVGLLLGHFGATGPLTWYIPFSANLFIREFGLMLFLYGVGLSAGPGFFSS 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492386624 463 VFRPEGLLWIATGFALTVVPVLIMGIVTFKWLKIDFGTMAGMLCGSMANPMALNYANDTIP-GDNPSVAYATVYPL 537
Cdd:TIGR01625 79 LKDGGGLLRINGGALITVVPTLLVAVALIKLLRINYALTAGMLAGATTNTPALDAANDTLRtSDLPALGYATVYPL 154
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK03818 |
PRK03818 |
putative transporter; Validated |
10-553 |
0e+00 |
|
putative transporter; Validated
Pssm-ID: 179654 [Multi-domain] Cd Length: 552 Bit Score: 798.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 10 EHSALQAVVVLSLISAIGLGLGKIHVCGISLGVTFVFFAGIIAGHF----GLSIDPQMLNYAESFGLVIFVYALGLQVGP 85
Cdd:PRK03818 1 MSDIALTVSILALVAVVGLWIGNIKIRGVGLGIGGVLFGGIIVGHFvsqfGLTLDSDMLHFIQEFGLILFVYTIGIQVGP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 86 GFFSSFRKGGVQLNMLATGVVLIGTLLTVLGSYGLGVSLPDMVGILCGATTNTPALGAAQQTLKQMGLESS---TPALGC 162
Cdd:PRK03818 81 GFFSSLRKSGLRLNLFAVLIVILGGLVTAILHKLFGIPLPVMLGIFSGAVTNTPALGAGQQILRDLGTPGDlvdQMGMGY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 163 AVAYPLGVVGVILAVLFIRKTLAHKEDLELKEKDDV-----NKPYIVAFQVHNPAIFNKSIKEIGGLNsYPKFVISRLWR 237
Cdd:PRK03818 161 AMAYPFGICGILLSMWLIRLIFRINVDKEAQEFESSsgnghELLQTINIRVENPNLHGKAIKDVPILN-GDKFVCSRLKR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 238 DGNVSIPTSEKIIKEGDRLLVITSEKNTPALTVLFGEQEhtdwnkeDIDWNAIDSQLISQRIVVTRPELNGKKLGSLHLR 317
Cdd:PRK03818 240 GDTLMVPSPDTIIQLGDLLHLVGQPEDLHKAQLVIGEEV-------DTSLSTRGTDLRSERVVVTNEKVLGKKLRDLHLK 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 318 NHYGINISRVYRSGVQLLATAELTLQLGDRLTVVGEAAAIQNVEKVLGNAVKSLKEPNLVAVFIGIVIGLALGAIPISIP 397
Cdd:PRK03818 313 NKYGVVISRLNRAGVELVASPDLSLQFGDILNLVGRPEAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPFFIP 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 398 GISAPVRLGLAGGPIIVGILIGTFGPRMHMVTYTTRSANLMLRALGLSLYLACLGLDAGAHFFDTVFRPEGLLWIATGFA 477
Cdd:PRK03818 393 GFPAALKLGLAGGPLIVALILGRIGSIGKLYWFMPPSANLALRELGIVLFLAVVGLKSGGDFVDTLVNGEGLSWIGYGFL 472
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492386624 478 LTVVPVLIMGIVTFKWLKIDFGTMAGMLCGSMANPMALNYANDTIP-GDNPSVAYATVYPLCMFLRVIIAQVLLMFF 553
Cdd:PRK03818 473 ITAVPLLIVGILARMLAKMNYLTLCGMLAGSMTDPPALAFANNLHPtSGAAALSYATVYPLVMFLRIITPQLLAVLF 549
|
|
| YbjL |
COG2985 |
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only]; ... |
8-553 |
0e+00 |
|
Uncharacterized membrane protein YbjL, putative transporter [General function prediction only];
Pssm-ID: 442224 [Multi-domain] Cd Length: 543 Bit Score: 593.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 8 FVEHSALQAVVVLSLISAIGLGLGKIHVCGISLGVTFVFFAGIIAGHFGlsIDPQMLNYAESFGLVIFVYALGLQVGPGF 87
Cdd:COG2985 3 LFELLVANPELALFLVIALGYLLGKIKIGGFSLGVAGVLFVGLLIGHFG--VTLHIPHFVKSLGLALFVYAIGLQVGPGF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 88 FSSFRKGGVQLNMLATGVVLIGTLLTVLGSYGLGVSLPDMVGILCGATTNTPALGAAQQTLKQMGLE---SSTPALGCAV 164
Cdd:COG2985 81 FASLKRDGLKLNLLAVVVVVLGLLVALALAKLFGLDPGLAAGLFAGALTNTPALGAAQDALGKLGLSkqlSANPAVGYAV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 165 AYPLGVVGVILAVLFIRKTLAHK-----EDLELKEKDDVNKPYIVAFQVHNPAIFNKSIKEIGGLNSyPKFVISRLWRDG 239
Cdd:COG2985 161 AYPFGVIGIILFVALLPKLFRIDldaeaKKLEAGEGSAYPPLVTRAYRVTNPNLVGKTVAELEALLG-TRVVISRIRRGG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 240 NVSIPTSEKIIKEGDRLLVITSEKNTPALTVLFGEQEHTDwnkedidwNAIDSQLISQRIVVTRPELNGKKLGSLHLRNH 319
Cdd:COG2985 240 EIIVPTPDTVLQEGDIVLVVGTREALEAAEALLGEEVDDS--------ELLDSDLDVRRIVVTNKEVAGKTLGELNLRNR 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 320 YGINISRVYRSGVQLLATAELTLQLGDRLTVVGEAAAIQNVEKVLGNAVKSLKEPNLVAVFIGIVIGLALGAIPISIPGI 399
Cdd:COG2985 312 FGVVITRVRRGGVELPATPDTVLQLGDRLTVVGPKEDVERVAKLLGNSERKLSETDLLPLGLGIVLGLLLGSIPIPLPGI 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 400 SaPVRLGLAGGPIIVGILIGTFGPRMHMVTYTTRSANLMLRALGLSLYLACLGLDAGAHFFDTVFRpEGLLWIATGFALT 479
Cdd:COG2985 392 P-PLSLGLAGGPLIVGLLLGRLGRTGPLVGYMPPSANLLLRELGLALFLAVVGLSAGPGFVETLQE-SGLLLFLLGALVT 469
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 492386624 480 VVPVLIMGIVTFKWLKIDFGTMAGMLCGSMANPMALNYANDTIPGDNPSVAYATVYPLCMFLRVIIAQVLLMFF 553
Cdd:COG2985 470 LVPLLVVLLVGRYVLKLNYLILLGALAGAMTSPPALAAANEAAGSDAPALGYATVYPLAMILLILLGQLLVLLL 543
|
|
| Asp-Al_Ex |
pfam06826 |
Predicted Permease Membrane Region; This family represents five transmembrane helices that are ... |
378-551 |
1.10e-43 |
|
Predicted Permease Membrane Region; This family represents five transmembrane helices that are normally found flanking (five either side) a pair of pfam02080 domains. This suggests that the paired regions form a ten helical structure, probably forming the pore, whereas the pfam02080) binds a ligand for export or regulation of the pore. Swiss:Q8L3K8 is described as a aspartate-alanine antiporter. In conjunction with Swiss:Q8L3K9 it forms a 'proton motive metabolic cycle catalyzed by an aspartate-alanine exchange'. The general conservation of domain architecture in this family suggests that they are functional orthologues.
Pssm-ID: 284291 [Multi-domain] Cd Length: 167 Bit Score: 152.73 E-value: 1.10e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 378 AVFIGIVIGLALGAIPISIPgisapVRLGLAGGPIIVGILIGTFGPRMHmvTYTTRSANLMLRALGLSLYLACLGLDAGA 457
Cdd:pfam06826 1 ALFLGIALGLLLGRIKISGG-----FSLGVAGGVLIVGLLLGHFGSTGP--TFMPISALSFLRELGLALFLAAVGLSAGP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 458 HFFDTVFRPeGLLWIATGFALTVVPVLIMGIVTFKWLKIDFGTMAGMLCGSMANPMALNYANDTIPG-DNPSVAYATVYP 536
Cdd:pfam06826 74 GFFSSLKKD-GLLLIGLALLVTVVPLLLALVLGKYVLKLDPGLLAGLLAGALTSTPALGAANDALAGsDIPALGYAVTYP 152
|
170
....*....|....*
gi 492386624 537 LCMFLRVIIAQVLLM 551
Cdd:pfam06826 153 FGVVGLILAGQVLAK 167
|
|
| YidE_YbjL_dupl |
TIGR01625 |
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is ... |
383-537 |
1.31e-42 |
|
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is duplicated the aspartate-alanine antiporter AspT, as well as HI0035 of Haemophilus influenzae, YidE and YbjL of E. coli, and a number of other known or putative transporters. Member proteins may have 0, 1, or 2 copies of TrkA potassium uptake domain pfam02080 between the duplications. The domain contains several apparent transmembrane regions and is proposed here to act in transport. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 130686 [Multi-domain] Cd Length: 154 Bit Score: 149.40 E-value: 1.31e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 383 IVIGLALGAIPISIPGisAPVRLGLAGGPIIVGILIGTFGPRMHMVTYTTRSANLMLRALGLSLYLACLGLDAGAHFFDT 462
Cdd:TIGR01625 1 LALGLLLGKIPIGLPG--FSIKLGNAGGVLFVGLLLGHFGATGPLTWYIPFSANLFIREFGLMLFLYGVGLSAGPGFFSS 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 492386624 463 VFRPEGLLWIATGFALTVVPVLIMGIVTFKWLKIDFGTMAGMLCGSMANPMALNYANDTIP-GDNPSVAYATVYPL 537
Cdd:TIGR01625 79 LKDGGGLLRINGGALITVVPTLLVAVALIKLLRINYALTAGMLAGATTNTPALDAANDTLRtSDLPALGYATVYPL 154
|
|
| PRK04972 |
PRK04972 |
putative transporter; Provisional |
17-550 |
4.89e-41 |
|
putative transporter; Provisional
Pssm-ID: 179905 [Multi-domain] Cd Length: 558 Bit Score: 156.04 E-value: 4.89e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 17 VVVLSLISAIGLGLGKIHVCGISLGVTF-VFFAGIIAGHFGLSIDPQMLNyaesFGLVIFVYALGLQVGPGFFSSFRKGG 95
Cdd:PRK04972 14 ILLLFVVLALGLCLGKLRLGSIQLGNSIgVLVVSLLLGQQHFSINTDALN----LGFMLFIFCVGVEAGPNFFSIFFRDG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 96 VQLNMLATGVVLIGTLLTVLGSYGLGVSLPDMVGILCGATTNTPALGAAQQTLK-------QMGLESSTPALGCAVAYPL 168
Cdd:PRK04972 90 KNYLMLALVMVGSALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRhsgaesrQLSLALDNLSLGYALTYLI 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 169 GVVGVILAVLFIRK-----------TLAHKEDLELKEKDDVNKPYIVAFQVhNPAIFN----KSIKEIgGLNSYPKFVIS 233
Cdd:PRK04972 170 GLVSLIVGARYLPKlqhqdlqtsaqQIARERGLDTDAQRKVYLPVIRAYRV-GPELVAwtdgKNLREL-GIYRQTGCYIE 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 234 RLWRDGNVSIPTSEKIIKEGDRLLVITSEKNTPALTVLFGEqehtdwNKEDIDWNAIDSQLISQRIVVTRPELNGKKLGS 313
Cdd:PRK04972 248 RIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRN------GKEVFDRDLLDMRIVTEEIVVKNHNAVGKRLSQ 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 314 LHLRNHyGINISRVYRSGVQLLATAELTLQLGDRLTVVGEAAAIQNVEKVLGNAVKSLKEPNLVAVFIGIVIGLALGAIP 393
Cdd:PRK04972 322 LKLTDH-GCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFIIGLMIGMIT 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 394 ISIPGISapVRLGLAGGPIIVGILIGTFGPRMHMVTYTTRSANLMLRALGLSLYLACLGLDAGAHFFDTvFRPEGLLWIA 473
Cdd:PRK04972 401 FQFSNFS--FGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLMVFMAGVGLSAGSGINNG-LGAVGGQMLI 477
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492386624 474 TGFALTVVPVLIMGIVTFKWLKIDFGTMAGMLCGSMANPMALNYANDTIPGDNPSVAYATVYPlcmflrviIAQVLL 550
Cdd:PRK04972 478 AGLIVSLVPVVICFLFGAYVLRMNRALLFGAIMGARTCAPAMEIISDTARSNIPALGYAGTYA--------IANVLL 546
|
|
| Asp-Al_Ex |
pfam06826 |
Predicted Permease Membrane Region; This family represents five transmembrane helices that are ... |
19-182 |
4.09e-37 |
|
Predicted Permease Membrane Region; This family represents five transmembrane helices that are normally found flanking (five either side) a pair of pfam02080 domains. This suggests that the paired regions form a ten helical structure, probably forming the pore, whereas the pfam02080) binds a ligand for export or regulation of the pore. Swiss:Q8L3K8 is described as a aspartate-alanine antiporter. In conjunction with Swiss:Q8L3K9 it forms a 'proton motive metabolic cycle catalyzed by an aspartate-alanine exchange'. The general conservation of domain architecture in this family suggests that they are functional orthologues.
Pssm-ID: 284291 [Multi-domain] Cd Length: 167 Bit Score: 135.01 E-value: 4.09e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 19 VLSLISAIGLGLGKIHVC-GISLGVT-FVFFAGIIAGHFG----LSIDPQMLNYAESFGLVIFVYALGLQVGPGFFSSFR 92
Cdd:pfam06826 1 ALFLGIALGLLLGRIKISgGFSLGVAgGVLIVGLLLGHFGstgpTFMPISALSFLRELGLALFLAAVGLSAGPGFFSSLK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 93 KGGVQLNMLATGVVLIGTLLT-VLGSYGLGVSLPDMVGILCGATTNTPALGAAQQTLKQMGLesstPALGCAVAYPLGVV 171
Cdd:pfam06826 81 KDGLLLIGLALLVTVVPLLLAlVLGKYVLKLDPGLLAGLLAGALTSTPALGAANDALAGSDI----PALGYAVTYPFGVV 156
|
170
....*....|.
gi 492386624 172 GVILAVLFIRK 182
Cdd:pfam06826 157 GLILAGQVLAK 167
|
|
| YidE_YbjL_dupl |
TIGR01625 |
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is ... |
25-168 |
2.20e-30 |
|
AspT/YidE/YbjL antiporter duplication domain; This model represents a domain that is duplicated the aspartate-alanine antiporter AspT, as well as HI0035 of Haemophilus influenzae, YidE and YbjL of E. coli, and a number of other known or putative transporters. Member proteins may have 0, 1, or 2 copies of TrkA potassium uptake domain pfam02080 between the duplications. The domain contains several apparent transmembrane regions and is proposed here to act in transport. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 130686 [Multi-domain] Cd Length: 154 Bit Score: 116.28 E-value: 2.20e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 25 AIGLGLGKIHVCG----ISLG-VTFVFFAGIIAGHFGLS------IDPQMLNYAESFGLVIFVYALGLQVGPGFFSSFRK 93
Cdd:TIGR01625 2 ALGLLLGKIPIGLpgfsIKLGnAGGVLFVGLLLGHFGATgpltwyIPFSANLFIREFGLMLFLYGVGLSAGPGFFSSLKD 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492386624 94 GGVQL--NMLATGVVLIGTLLTVLGSYGLGVSLPDMVGILCGATTNTPALGAAQQTLKQMGLesstPALGCAVAYPL 168
Cdd:TIGR01625 82 GGGLLriNGGALITVVPTLLVAVALIKLLRINYALTAGMLAGATTNTPALDAANDTLRTSDL----PALGYATVYPL 154
|
|
| TrkA_C |
pfam02080 |
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of ... |
295-364 |
9.08e-10 |
|
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified ligand. The domain is predicted to adopt an all beta structure.
Pssm-ID: 460440 [Multi-domain] Cd Length: 70 Bit Score: 54.92 E-value: 9.08e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 295 ISQRIVVTRPELNGKKLGSLHLRNHYGINISRVYRSGVQLLATAELTLQLGDRLTVVGEAAAIQNVEKVL 364
Cdd:pfam02080 1 LVEVTVPENSPLVGKTLKELNLPERFGVRIVAIRRGGRLIIPSGDTVLEAGDRLLVIGTPDDLAALRELL 70
|
|
| KhtT |
COG0490 |
K+/H+ antiporter KhtSTU, c-di-AMP-binding regulatory subunit KhtT, contains RCK_C (TrkA_C) ... |
305-364 |
2.42e-04 |
|
K+/H+ antiporter KhtSTU, c-di-AMP-binding regulatory subunit KhtT, contains RCK_C (TrkA_C) domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];
Pssm-ID: 440256 [Multi-domain] Cd Length: 140 Bit Score: 41.45 E-value: 2.42e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 492386624 305 ELNGKKLGSLHLRNHYGINISRVYRSGVQLLA-TAELTLQLGDRLTVVGEAAAIQNVEKVL 364
Cdd:COG0490 80 PLVGKTLGELNLRQRTGVTVVAIRRGGEVILSpGPDTVLEAGDTLVVVGTREQLERLEELL 140
|
|
| TrkA_C |
pfam02080 |
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of ... |
210-272 |
3.21e-04 |
|
TrkA-C domain; This domain is often found next to the pfam02254 domain. The exact function of this domain is unknown. It has been suggested that it may bind an unidentified ligand. The domain is predicted to adopt an all beta structure.
Pssm-ID: 460440 [Multi-domain] Cd Length: 70 Bit Score: 39.13 E-value: 3.21e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 492386624 210 NPAIFNKSIKEIGgLNSYPKFVISRLWRDGNVSIPTSEKIIKEGDRLLVITSEKNTPALTVLF 272
Cdd:pfam02080 9 NSPLVGKTLKELN-LPERFGVRIVAIRRGGRLIIPSGDTVLEAGDRLLVIGTPDDLAALRELL 70
|
|
| TrkA |
COG0569 |
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ... |
295-348 |
1.85e-03 |
|
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];
Pssm-ID: 440335 [Multi-domain] Cd Length: 296 Bit Score: 40.44 E-value: 1.85e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 492386624 295 ISQRIVVTRPELNGKKLGSLHLRNHYGINISRVYRSGVQLLATAELTLQLGDRL 348
Cdd:COG0569 242 IVEVTVPEGSPLVGKTLKELDLRERYGVTVVAIKRGGEVIIPSGDTVLEAGDEL 295
|
|
| Lys_export |
pfam03956 |
Lysine exporter LysO; Members of this family contain a conserved core of four predicted ... |
44-133 |
2.09e-03 |
|
Lysine exporter LysO; Members of this family contain a conserved core of four predicted transmembrane segments. Some members have an additional pair of N-terminal transmembrane helices. This family includes lysine exporter LysO (YbjE) from E. coli.
Pssm-ID: 427613 Cd Length: 190 Bit Score: 39.33 E-value: 2.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 492386624 44 FVFFAGIIAGHFGLSIDPQMLNYAESFGLVIFVYALGLQVG--PGFFSSFRKGGVQLnMLATGVVLIGTLL-TVLGSYGL 120
Cdd:pfam03956 2 AFFIAGILLGYFLLPPADLLLDDLSTYALYLLLFLVGIDLGsnRSLLQILRRLGPRI-LLLPLATILGSLLgGALASLLL 80
|
90
....*....|...
gi 492386624 121 GVSLPDMVGILCG 133
Cdd:pfam03956 81 GLSLKESLAVGSG 93
|
|
| trkA |
PRK09496 |
Trk system potassium transporter TrkA; |
203-278 |
2.44e-03 |
|
Trk system potassium transporter TrkA;
Pssm-ID: 236541 [Multi-domain] Cd Length: 453 Bit Score: 40.49 E-value: 2.44e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 492386624 203 IVAFQV-HNPAIFNKSIKEIGGLNSYPKFVISRLWRDGNVSIPTSEKIIKEGDRLLVITSEKNTPALTVLFGEQEHT 278
Cdd:PRK09496 154 LVEVKVyEGSPLVGKPLSDLREHFPDIDVRVVAIFRGGRLIIPRGDTVIEAGDEVYFIGAREHIRAVMSEFGRLEKP 230
|
|
| |
