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Conserved domains on  [gi|490254718|ref|WP_004152694|]
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MULTISPECIES: phosphonate ABC transporter, permease protein PhnE [Gammaproteobacteria]

Protein Classification

PhnE/PtxC family ABC transporter permease( domain architecture ID 11466536)

PhnE/PtxC family ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of phosphonate, phosphate, or phosphite ions

Gene Ontology:  GO:0043190|GO:0140359|GO:0042626|GO:0016020
PubMed:  25750732|24638992|18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 33-274 3.34e-101

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 295.45  E-value: 3.34e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  33 VAIVFGVVLLACWYVGLLDATTLLNGLPSIATLAGEAMPPDFSGYRSWIRPLIDTLAMSIAGTAIAVVFSLVVAFVAARN 112
Cdd:COG3639    2 LLLALLALLVWSLWGLEFDLGRLIDGLPNLADFLSRFFPPDWSYLPDLLSALLETLAIALLGTLLGAVLALPLAFLAARN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718 113 TAPHPLVFGVARVLLNALRSVPELIMGIIFVAAVGFGALPGVLALGLHSVGMVSKFFAEAIEHVDEAPVEAARAAGATPM 192
Cdd:COG3639   82 LAPNPWVRLLARRLLNVLRAIPELVWALIFVAAVGLGPFAGVLALAIHTIGFLGKLFAEAIEEIDPGPVEALRATGASRL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718 193 QVLLHAVLPQVTPQFADVAIYRWEYNFRASTVMGMVGAGGIGFELMGSLRIMQYQEVAAILLVILAMVTLVDAFSGVLRK 272
Cdd:COG3639  162 QVIRYGVLPQVLPQFLSYTLYRFEINIRAATVLGLVGAGGIGLLLNEAIRLFQYDEVAAILLVILVLVLLIDLLSARLRR 241


                 ..
gi 490254718 273 RF 274
Cdd:COG3639  242 RL 243
 
Name Accession Description Interval E-value
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 33-274 3.34e-101

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 295.45  E-value: 3.34e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  33 VAIVFGVVLLACWYVGLLDATTLLNGLPSIATLAGEAMPPDFSGYRSWIRPLIDTLAMSIAGTAIAVVFSLVVAFVAARN 112
Cdd:COG3639    2 LLLALLALLVWSLWGLEFDLGRLIDGLPNLADFLSRFFPPDWSYLPDLLSALLETLAIALLGTLLGAVLALPLAFLAARN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718 113 TAPHPLVFGVARVLLNALRSVPELIMGIIFVAAVGFGALPGVLALGLHSVGMVSKFFAEAIEHVDEAPVEAARAAGATPM 192
Cdd:COG3639   82 LAPNPWVRLLARRLLNVLRAIPELVWALIFVAAVGLGPFAGVLALAIHTIGFLGKLFAEAIEEIDPGPVEALRATGASRL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718 193 QVLLHAVLPQVTPQFADVAIYRWEYNFRASTVMGMVGAGGIGFELMGSLRIMQYQEVAAILLVILAMVTLVDAFSGVLRK 272
Cdd:COG3639  162 QVIRYGVLPQVLPQFLSYTLYRFEINIRAATVLGLVGAGGIGLLLNEAIRLFQYDEVAAILLVILVLVLLIDLLSARLRR 241


                 ..
gi 490254718 273 RF 274
Cdd:COG3639  242 RL 243
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 33-274 1.64e-96

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 283.66  E-value: 1.64e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718   33 VAIVFGVVLLACWYVGLlDATTLLNGLPSIATLAGEAMPPDFSGYRSWIRPLIDTLAMSIAGTAIAVVFSLVVAFVAARN 112
Cdd:TIGR01097  10 LALLVALYVWAFALLGF-DLARLLAGPGQMADLLGRMFPPDWSYLPRILKALLETLAMAILGTVLAAVLAVPLALLAARN 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  113 TAPHPLVFGVARVLLNALRSVPELIMGIIFVAAVGFGALPGVLALGLHSVGMVSKFFAEAIEHVDEAPVEAARAAGATPM 192
Cdd:TIGR01097  89 ITPSPWLYGLARLLLNFLRAIPELVWALIFVAAVGLGPFAGVLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKL 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  193 QVLLHAVLPQVTPQFADVAIYRWEYNFRASTVMGMVGAGGIGFELMGSLRIMQYQEVAAILLVILAMVTLVDAFSGVLRK 272
Cdd:TIGR01097 169 QVIRYGVLPQVLPQFLSYTLYRFEINVRAAAVLGLVGAGGIGLELDTAIGLFDYDEVSAIILVILVVVVIIDLISARLRR 248


                  ..
gi 490254718  273 RF 274
Cdd:TIGR01097 249 RL 250
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 84-262 2.32e-13

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 66.92  E-value: 2.32e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  84 LIDTLAMSIAGTAIAVVFSLVVAFVAARNTaphPLVFGVARVLLNALRSVPELIMGIIFVAAVG---------FGALPGV 154
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKR---GKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGvllgwgilpGLGLPAL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718 155 LALGLHSVGMVSKFFAEAIEHVDEAPVEAARAAGATPMQVLLHAVLPQVTPQFADVAIYRWEYNFRASTVMGMVGAGGIG 234
Cdd:cd06261   78 ILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAP 157

                        170       180       190
                 ....*....|....*....|....*....|...
gi 490254718 235 FELMGSLRIMQYQE-----VAAILLVILAMVTL 262
Cdd:cd06261  158 GPGTGLLLIFAILFpgdlgVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 102-275 1.68e-12

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 64.24  E-value: 1.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  102 SLVVAFVAARNtaPHPLVFGVARVLLNALRSVPELIMGIIFVAA-----VGFGALPGVLALGLHSVGMVSKFFAEAIEHV 176
Cdd:pfam00528   1 GIPLGIIAALR--RGRRLDRLLRPLIDLLQALPSFVLAILLVVIailsiLGHGILPAIILALLGWAGYARLIRRAALRSL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  177 DEAPVEAARAAGATPMQVLLHAVLPQVTPQFADVAIYRWEYNFRASTVMGMVGAG-GIGFELMGSLRIMQYQE----VAA 251
Cdd:pfam00528  79 PSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpGLGLLLIEAILGYDYPEiqgpVLA 158

                         170       180
                  ....*....|....*....|....
gi 490254718  252 ILLVILAMVTLVDAFSGVLRKRFK 275
Cdd:pfam00528 159 AALILLLLNLLVDILQRLLDPRVR 182
PRK15111 PRK15111
peptide ABC transporter permease SapC;
86-206 2.02e-04

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 42.00  E-value: 2.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  86 DTLAMSIAGTAIAVVFSLVVAFVAARNTAPHPLVFGVARVL--------LNALRSVPELIMGIIFVAAVGFGALPGVLAL 157
Cdd:PRK15111  86 DVLSRLLSGAAPTVGGAFVVTLAATLCGLVLGVFAGATHGLrsavlnhiLDTLLSIPSLLLAIIVVAFAGPSLSHAMFAV 165

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 490254718 158 GLHSVG-MVSKFFAEAIEHVDEAPVEAARAAGATPMQVLLHAVLPQVTPQ 206
Cdd:PRK15111 166 WLALLPrMVRSIYSAVHDELEKEYVIAARLDGASTLNILWYAVLPNITAG 215
 
Name Accession Description Interval E-value
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 33-274 3.34e-101

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 295.45  E-value: 3.34e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  33 VAIVFGVVLLACWYVGLLDATTLLNGLPSIATLAGEAMPPDFSGYRSWIRPLIDTLAMSIAGTAIAVVFSLVVAFVAARN 112
Cdd:COG3639    2 LLLALLALLVWSLWGLEFDLGRLIDGLPNLADFLSRFFPPDWSYLPDLLSALLETLAIALLGTLLGAVLALPLAFLAARN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718 113 TAPHPLVFGVARVLLNALRSVPELIMGIIFVAAVGFGALPGVLALGLHSVGMVSKFFAEAIEHVDEAPVEAARAAGATPM 192
Cdd:COG3639   82 LAPNPWVRLLARRLLNVLRAIPELVWALIFVAAVGLGPFAGVLALAIHTIGFLGKLFAEAIEEIDPGPVEALRATGASRL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718 193 QVLLHAVLPQVTPQFADVAIYRWEYNFRASTVMGMVGAGGIGFELMGSLRIMQYQEVAAILLVILAMVTLVDAFSGVLRK 272
Cdd:COG3639  162 QVIRYGVLPQVLPQFLSYTLYRFEINIRAATVLGLVGAGGIGLLLNEAIRLFQYDEVAAILLVILVLVLLIDLLSARLRR 241


                 ..
gi 490254718 273 RF 274
Cdd:COG3639  242 RL 243
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 33-274 1.64e-96

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 283.66  E-value: 1.64e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718   33 VAIVFGVVLLACWYVGLlDATTLLNGLPSIATLAGEAMPPDFSGYRSWIRPLIDTLAMSIAGTAIAVVFSLVVAFVAARN 112
Cdd:TIGR01097  10 LALLVALYVWAFALLGF-DLARLLAGPGQMADLLGRMFPPDWSYLPRILKALLETLAMAILGTVLAAVLAVPLALLAARN 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  113 TAPHPLVFGVARVLLNALRSVPELIMGIIFVAAVGFGALPGVLALGLHSVGMVSKFFAEAIEHVDEAPVEAARAAGATPM 192
Cdd:TIGR01097  89 ITPSPWLYGLARLLLNFLRAIPELVWALIFVAAVGLGPFAGVLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKL 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  193 QVLLHAVLPQVTPQFADVAIYRWEYNFRASTVMGMVGAGGIGFELMGSLRIMQYQEVAAILLVILAMVTLVDAFSGVLRK 272
Cdd:TIGR01097 169 QVIRYGVLPQVLPQFLSYTLYRFEINVRAAAVLGLVGAGGIGLELDTAIGLFDYDEVSAIILVILVVVVIIDLISARLRR 248


                  ..
gi 490254718  273 RF 274
Cdd:TIGR01097 249 RL 250
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 84-262 2.32e-13

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 66.92  E-value: 2.32e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  84 LIDTLAMSIAGTAIAVVFSLVVAFVAARNTaphPLVFGVARVLLNALRSVPELIMGIIFVAAVG---------FGALPGV 154
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKR---GKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGvllgwgilpGLGLPAL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718 155 LALGLHSVGMVSKFFAEAIEHVDEAPVEAARAAGATPMQVLLHAVLPQVTPQFADVAIYRWEYNFRASTVMGMVGAGGIG 234
Cdd:cd06261   78 ILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAP 157

                        170       180       190
                 ....*....|....*....|....*....|...
gi 490254718 235 FELMGSLRIMQYQE-----VAAILLVILAMVTL 262
Cdd:cd06261  158 GPGTGLLLIFAILFpgdlgVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 102-275 1.68e-12

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 64.24  E-value: 1.68e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  102 SLVVAFVAARNtaPHPLVFGVARVLLNALRSVPELIMGIIFVAA-----VGFGALPGVLALGLHSVGMVSKFFAEAIEHV 176
Cdd:pfam00528   1 GIPLGIIAALR--RGRRLDRLLRPLIDLLQALPSFVLAILLVVIailsiLGHGILPAIILALLGWAGYARLIRRAALRSL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  177 DEAPVEAARAAGATPMQVLLHAVLPQVTPQFADVAIYRWEYNFRASTVMGMVGAG-GIGFELMGSLRIMQYQE----VAA 251
Cdd:pfam00528  79 PSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpGLGLLLIEAILGYDYPEiqgpVLA 158

                         170       180
                  ....*....|....*....|....
gi 490254718  252 ILLVILAMVTLVDAFSGVLRKRFK 275
Cdd:pfam00528 159 AALILLLLNLLVDILQRLLDPRVR 182
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 33-274 2.62e-12

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 65.17  E-value: 2.62e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  33 VAIVFGVVLLACWYVGLLDATTLLNGLPSIATLAGEAMppDFSGYRSWIRPLIDTLAMSIAGTAIAVVFSLVVAFVAARN 112
Cdd:COG0600   14 LPLLSLALLLALWELAARLGLVPPFLLPSPSAVLAALV--ELLASGELWEHLLASLLRVLLGFALAALLGVPLGLLLGLS 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718 113 taphPLVFGVARVLLNALRSVPELIMGIIFVAAVGFGALPGVLALGLHSVGMVSKFFAEAIEHVDEAPVEAARAAGATPM 192
Cdd:COG0600   92 ----RLLRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARSLGASRW 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718 193 QVLLHAVLPQVTPQFADVAIYRWEYNFRASTVMGMVGAG-GIGFELMGSLRIMQYQEVAAILLVILAMVTLVDAFSGVLR 271
Cdd:COG0600  168 QILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASsGLGYLILDARQLLDTDLVFAAILVIGLLGLLLDLLLRLLE 247


                 ...
gi 490254718 272 KRF 274
Cdd:COG0600  248 RRL 250
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 88-274 1.08e-10

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 59.68  E-value: 1.08e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  88 LAMSIAGTAIAVVFSLVVAFVAARNTAPHPLVFGVArvllNALRSVPELIMGIIFVAAVGFGALPGVLALGLHSVGMVSK 167
Cdd:COG1174   24 LLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVA----NILQTIPSLALLALLIPLLGIGPAPAIIALVLYALLPILR 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718 168 FFAEAIEHVDEAPVEAARAAGATPMQVLLHAVLPQVTPQ-FADVaiyrweynfRASTVMGM--------VGAGGIGFELM 238
Cdd:COG1174  100 NTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPViLAGI---------RTAAVQNIgtatlaalIGAGGLGDLIF 170

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 490254718 239 GSLRIMQYQEV--AAILLVILAMVtlVDAFSGVLRKRF 274
Cdd:COG1174  171 DGLQLNNTALIlaGAILVALLALL--VDLLLALLERLL 206
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
 84-234 4.50e-10

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 441614  Cd Length: 220  Bit Score: 58.14  E-value: 4.50e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  84 LIDTLAMSIAGTAIAVVFSL---VVAFVAARN-TAPHPLVFGVARVLLNALRSVPELIMGII------FVAAVGFGALPG 153
Cdd:COG2011   16 TGETLYMVGVSTLIAVLLGLplgVLLVLTRPGgLLPNPVLYRVLGVIVNIFRSIPFIILLVAlipltrLIVGTSIGTTAA 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718 154 VLALGLHSVGMVSKFFAEAIEHVDEAPVEAARAAGATPMQVLLHAVLPQVTPQ------FADVAIyrweynFRASTVMGM 227
Cdd:COG2011   96 IVPLTIAAIPFFARLVENALREVDPGVIEAAQAMGASPWQIIFKVLLPEALPSlilgltVTLISL------IGYSAMAGA 169


                 ....*..
gi 490254718 228 VGAGGIG 234
Cdd:COG2011  170 VGGGGLG 176
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 73-275 5.63e-10

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 57.78  E-value: 5.63e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  73 DFSGYRSWIRPLIDTLAMSIAGTAIAVVFSLVVAFVAA--RnTAPHPLVFGVARVLLNALRSVPELImgIIFVAAVGFGA 150
Cdd:COG0765    4 DFSVLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLAlaR-LSPNPVLRWLATAYVEFFRGTPLLV--QLFFIYFGLPL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718 151 L--------PGVLALGLHSvgmvSKFFAE----AIEHVDEAPVEAARAAGATPMQVLLHAVLPQ----VTPQFADVAIyr 214
Cdd:COG0765   81 LgidlspfvAAVIALTLNS----AAYLAEivraGIQSVPKGQWEAARALGLSRWQTMRRIILPQalriILPPLGNEFI-- 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490254718 215 weYNFRASTVMGMVGAggigFELMGSLRIM--QYQEVAAILLVI----LAMVTLVDAFSGVLRKRFK 275
Cdd:COG0765  155 --SLLKDTSLVSVIGV----PELTRAAQQIasRTFRPFEVYLVAaliyLVLTLPLSLLARRLERRLA 215
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
19-263 5.04e-07

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 50.54  E-value: 5.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  19 LRGFGLGWWRQLGQVAIVFGVVLLACWYVGLLDATTLLNGLPSIATLAGEAMPPDFSGYrswIRPLIDTLAMSIAGTAIA 98
Cdd:COG1178  278 PRRVKLGRWRWLALALCLLLVLLGLLLPLLALLLWSLTKALDDNLTLDNYRFVLLDPSL---LRALLNSLLLALLAALLA 354

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  99 VVFSLVVAFVAARntAPHPLVfGVARVLLNALRSVPELIMGIIFVAAVGFGALPG--------VLALGLHSVGMVSKFFA 170
Cdd:COG1178  355 VLLALLLAYLVRR--RRGRLA-RLLDRLAMLPYAVPGIVLGLGLLLLFNRPLPLLlygtlailVLAYVVRFLPFALRSLE 431

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718 171 EAIEHVDEAPVEAARAAGATPMQVLLHAVLPQVTPQFADVAIYRWeynfraSTVMGMVGA----GGIGFELMgSLRIMQ- 245
Cdd:COG1178  432 AALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVF------VTSMKELSAtlllRPPGFETL-AVLIYQl 504

                        250       260
                 ....*....|....*....|...
gi 490254718 246 -----YQEVAAILLVILAMVTLV 263
Cdd:COG1178  505 assgrYGEAAALALLLVLVSLLP 527
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 87-206 6.35e-06

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 46.26  E-value: 6.35e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  87 TLAMSIAGTAIAVVFSLVVAFVAArntaphplVFG-----VARVLLNALRSVPELIMGIIFVAAVGFGALPGVLALGLHS 161
Cdd:COG1173   81 SLLVGLLAVLIALVIGVLLGLLAG--------YFGgwvdaVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTG 152

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 490254718 162 VGMVSKFF-AEAIEHVDEAPVEAARAAGATPMQVLLHAVLPQVTPQ 206
Cdd:COG1173  153 WPGYARLVrAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPP 198
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
62-208 1.17e-04

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 43.23  E-value: 1.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  62 IATLAGEAMPPDFSGYRSWI------RPLIDTLAMSIAGTAIAVVFSLVVAFVAARNTAPHPLVFgvaRVLLNALRSVPE 135
Cdd:COG1178   28 LLALLLRAFTDGLANFWALLsdpylwRALGNTLLLALLVTLLSLLLGVPLAWLLARTDFPGRRLL---RWLLLLPLALPP 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718 136 LIMGIIFVAAVGF--------------------GALPGVLALGLHSVGMVSKFFAEAIEHVDEAPVEAARAAGATPMQVL 195
Cdd:COG1178  105 YVVALAWIALFGPngllntllralfgleppdiyGLGGIILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAF 184

                        170
                 ....*....|...
gi 490254718 196 LHAVLPQVTPQFA 208
Cdd:COG1178  185 RRVTLPLLRPAIA 197
PRK15111 PRK15111
peptide ABC transporter permease SapC;
86-206 2.02e-04

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 42.00  E-value: 2.02e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  86 DTLAMSIAGTAIAVVFSLVVAFVAARNTAPHPLVFGVARVL--------LNALRSVPELIMGIIFVAAVGFGALPGVLAL 157
Cdd:PRK15111  86 DVLSRLLSGAAPTVGGAFVVTLAATLCGLVLGVFAGATHGLrsavlnhiLDTLLSIPSLLLAIIVVAFAGPSLSHAMFAV 165

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 490254718 158 GLHSVG-MVSKFFAEAIEHVDEAPVEAARAAGATPMQVLLHAVLPQVTPQ 206
Cdd:PRK15111 166 WLALLPrMVRSIYSAVHDELEKEYVIAARLDGASTLNILWYAVLPNITAG 215
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 78-205 2.32e-04

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 41.64  E-value: 2.32e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  78 RSWIRPLIDTLAMSIAGTAIAVVFSLVVAFVAARNTAPhplVFGVARVLLNALRSVPELIMGI-IFVAAVGFGALPG--- 153
Cdd:COG1177   57 PRLLDALLNSLLIALLSTLLATVLGTPAALALARYRFR---GRRLLLALLLLPLVVPGIVLGVaLLLLFSALGLSGGlwg 133

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490254718 154 -VLALGLHSVGMVSKFFAEAIEHVDEAPVEAARAAGATPMQVLLHAVLPQVTP 205
Cdd:COG1177  134 lILAHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAP 186
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
116-234 5.36e-04

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 40.10  E-value: 5.36e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718 116 HPLVFGVARVLLNALRSVPELIMGII------FVAAVGFGALPGVLALGLHSVGMVSKFFAEAIEHVDEAPVEAARAAGA 189
Cdd:PRK10782  49 NAKLYRTLSALVNIFRSIPFIILLVWmipftrVIVGTSIGLQAAIVPLTVGAAPFIARMVENALLEIPTGLIEASRAMGA 128

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 490254718 190 TPMQVLLHAVLPQVTPQFADVAIYRWEYNFRASTVMGMVGAGGIG 234
Cdd:PRK10782 129 TPMQIVRKVLLPEALPGLVNAATITLITLVGYSAMGGAVGAGGLG 173
3a0107s02c TIGR00974
phosphate ABC transporter, permease protein PstA; This model describes PtsA, one of a pair of ...
 33-201 2.36e-03

phosphate ABC transporter, permease protein PstA; This model describes PtsA, one of a pair of permease proteins in the ABC (high affinity) phosphate transporter. In a number of species, this permease is fused with the PtsC protein (TIGR02138). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273373  Cd Length: 271  Bit Score: 38.76  E-value: 2.36e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718   33 VAIVFGVVLLACWYVGLLDATTLLNGLPSIaTLAGEAMPPDFSGYRSWIRP-LIDTLAMSIAGTAIAVVFSLVVAFVAAR 111
Cdd:TIGR00974   5 TFISLLSALLALLPLIWILWYILIKGLPAL-NLEFFTKSPTPTGAEGGIGPaIVGTLLLTLLAIVIAVPLGIGAAIYLAE 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  112 nTAPHPLVFGVARVLLNALRSVPELIMGI----IFVAAV---GFGALPGVLALGLHSVGMVSKFFAEAIEHVDEAPVEAA 184
Cdd:TIGR00974  84 -YANGSRFTKIIRFAVDILAGVPSIVVGLfgygFFVLTYlggGFSLLAGALALALLILPVIIRTTEEALKAVPKDLREAS 162

                         170
                  ....*....|....*..
gi 490254718  185 RAAGATPMQVLLHAVLP 201
Cdd:TIGR00974 163 LALGATKWQTIFKVVLP 179
PstA COG0581
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 84-205 3.65e-03

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440346 [Multi-domain]  Cd Length: 259  Bit Score: 38.09  E-value: 3.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490254718  84 LIDTLAMSIAGTAIAVVFSLVVAFVAARNTAPHPLVfGVARVLLNALRSVPELIMGI----IFVAAVGFG--ALPGVLAL 157
Cdd:COG0581   43 IVGTLLLVLLATLIAVPLGVLAAIYLAEYARGGRLA-RLIRFAIDVLAGVPSIVYGLfgyaLFVLTLGLGfsLLAGALAL 121

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 490254718 158 GLHSVGMVSKFFAEAIEHVDEAPVEAARAAGATPMQVLLHAVLPQVTP 205
Cdd:COG0581  122 ALLMLPVVIRTTEEALRLVPNSLREASYALGATKWQTIRKVVLPAALP 169
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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