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Conserved domains on  [gi|489079894|ref|WP_002989831|]
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DUF1831 domain-containing protein [Streptococcus pyogenes]

Protein Classification

DUF1831 domain-containing protein( domain architecture ID 10556114)

DUF1831 domain-containing protein similar to Lactobacillus plantarum LP2179 that may paly a role in amino-acid metabolism

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF1831 pfam08866
Putative amino acid metabolism; Solution of the structure of the Lactobacillus plantarum ...
 2-110 1.96e-52

Putative amino acid metabolism; Solution of the structure of the Lactobacillus plantarum protein from this family has indicated a potential new fold with remote similarities to TBP-like (TATA-binding protein) structures. This similarity, in combination with genomic context analysis, leads us to propose an involvement in amino-acid metabolism. The potentially novel fold is an alpha + beta fold comprising two beta sheets packed against a single helix. The enzyme is present in the cytosol.


:

Pssm-ID: 430273  Cd Length: 110  Bit Score: 160.06  E-value: 1.96e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079894    2 AFEKEIKLKDCKYLYTISPNIKKYTLRDTTFSQTKVGHYQLIRLLEKIPNSGDGFPLKITINKELTGFKLAITDQSGLRL 81
Cdd:pfam08866   1 AFEKTVQLKGDTKTYTLSPNIKKYTLRDLGFVETKAGNFQLERSLDPTSPYNQGFKLKITINKDLDGFKMSVTTANGLRN 80

                          90       100
                  ....*....|....*....|....*....
gi 489079894   82 VNIFKTKDNQILQDKFYFLMDSLVEREIF 110
Cdd:pfam08866  81 VNIFKNEQHAPLVEQLYFILDDLIDRKIL 109
 
Name Accession Description Interval E-value
DUF1831 pfam08866
Putative amino acid metabolism; Solution of the structure of the Lactobacillus plantarum ...
 2-110 1.96e-52

Putative amino acid metabolism; Solution of the structure of the Lactobacillus plantarum protein from this family has indicated a potential new fold with remote similarities to TBP-like (TATA-binding protein) structures. This similarity, in combination with genomic context analysis, leads us to propose an involvement in amino-acid metabolism. The potentially novel fold is an alpha + beta fold comprising two beta sheets packed against a single helix. The enzyme is present in the cytosol.


Pssm-ID: 430273  Cd Length: 110  Bit Score: 160.06  E-value: 1.96e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079894    2 AFEKEIKLKDCKYLYTISPNIKKYTLRDTTFSQTKVGHYQLIRLLEKIPNSGDGFPLKITINKELTGFKLAITDQSGLRL 81
Cdd:pfam08866   1 AFEKTVQLKGDTKTYTLSPNIKKYTLRDLGFVETKAGNFQLERSLDPTSPYNQGFKLKITINKDLDGFKMSVTTANGLRN 80

                          90       100
                  ....*....|....*....|....*....
gi 489079894   82 VNIFKTKDNQILQDKFYFLMDSLVEREIF 110
Cdd:pfam08866  81 VNIFKNEQHAPLVEQLYFILDDLIDRKIL 109
 
Name Accession Description Interval E-value
DUF1831 pfam08866
Putative amino acid metabolism; Solution of the structure of the Lactobacillus plantarum ...
 2-110 1.96e-52

Putative amino acid metabolism; Solution of the structure of the Lactobacillus plantarum protein from this family has indicated a potential new fold with remote similarities to TBP-like (TATA-binding protein) structures. This similarity, in combination with genomic context analysis, leads us to propose an involvement in amino-acid metabolism. The potentially novel fold is an alpha + beta fold comprising two beta sheets packed against a single helix. The enzyme is present in the cytosol.


Pssm-ID: 430273  Cd Length: 110  Bit Score: 160.06  E-value: 1.96e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489079894    2 AFEKEIKLKDCKYLYTISPNIKKYTLRDTTFSQTKVGHYQLIRLLEKIPNSGDGFPLKITINKELTGFKLAITDQSGLRL 81
Cdd:pfam08866   1 AFEKTVQLKGDTKTYTLSPNIKKYTLRDLGFVETKAGNFQLERSLDPTSPYNQGFKLKITINKDLDGFKMSVTTANGLRN 80

                          90       100
                  ....*....|....*....|....*....
gi 489079894   82 VNIFKTKDNQILQDKFYFLMDSLVEREIF 110
Cdd:pfam08866  81 VNIFKNEQHAPLVEQLYFILDDLIDRKIL 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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