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Conserved domains on  [gi|488409210|ref|WP_002478595|]
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MULTISPECIES: beta-class phenol-soluble modulin [Staphylococcus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PSMbeta super family cl05183
Phenol-soluble modulin beta protein; This family consists of several different short ...
 1-43 1.79e-07

Phenol-soluble modulin beta protein; This family consists of several different short Staphylococcal proteins known as the phenol-soluble modulin beta proteins. The family contains SLUSH A, B and C proteins as well as haemolysin and gonococcal growth inhibitor. Some strains of the coagulase-negative Staphylococcus lugdunensis produce a synergistic hemolytic activity (SLUSH), phenotypically similar to the delta-hemolysin of S. aureus. Gonococcal growth inhibitor from Staphylococcus act on the cytoplasmic membrane of the gonococcal cell causing cytoplasmic leakage and, eventually, death.


The actual alignment was detected with superfamily member pfam05480:

Pssm-ID: 428486  Cd Length: 43  Bit Score: 41.51  E-value: 1.79e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 488409210   1 MSGIIEAITKAVQAGLDKDWATMGTSIAEALAKGIDAISGLFG 43
Cdd:pfam05480  1 MTKLAEAIKNTVQAAIAHDWAKLGTSIVDIVENGVGLLSKIFG 43
 
Name Accession Description Interval E-value
PSMbeta pfam05480
Phenol-soluble modulin beta protein; This family consists of several different short ...
 1-43 1.79e-07

Phenol-soluble modulin beta protein; This family consists of several different short Staphylococcal proteins known as the phenol-soluble modulin beta proteins. The family contains SLUSH A, B and C proteins as well as haemolysin and gonococcal growth inhibitor. Some strains of the coagulase-negative Staphylococcus lugdunensis produce a synergistic hemolytic activity (SLUSH), phenotypically similar to the delta-hemolysin of S. aureus. Gonococcal growth inhibitor from Staphylococcus act on the cytoplasmic membrane of the gonococcal cell causing cytoplasmic leakage and, eventually, death.


Pssm-ID: 428486  Cd Length: 43  Bit Score: 41.51  E-value: 1.79e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 488409210   1 MSGIIEAITKAVQAGLDKDWATMGTSIAEALAKGIDAISGLFG 43
Cdd:pfam05480  1 MTKLAEAIKNTVQAAIAHDWAKLGTSIVDIVENGVGLLSKIFG 43
 
Name Accession Description Interval E-value
PSMbeta pfam05480
Phenol-soluble modulin beta protein; This family consists of several different short ...
 1-43 1.79e-07

Phenol-soluble modulin beta protein; This family consists of several different short Staphylococcal proteins known as the phenol-soluble modulin beta proteins. The family contains SLUSH A, B and C proteins as well as haemolysin and gonococcal growth inhibitor. Some strains of the coagulase-negative Staphylococcus lugdunensis produce a synergistic hemolytic activity (SLUSH), phenotypically similar to the delta-hemolysin of S. aureus. Gonococcal growth inhibitor from Staphylococcus act on the cytoplasmic membrane of the gonococcal cell causing cytoplasmic leakage and, eventually, death.


Pssm-ID: 428486  Cd Length: 43  Bit Score: 41.51  E-value: 1.79e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 488409210   1 MSGIIEAITKAVQAGLDKDWATMGTSIAEALAKGIDAISGLFG 43
Cdd:pfam05480  1 MTKLAEAIKNTVQAAIAHDWAKLGTSIVDIVENGVGLLSKIFG 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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