|
Name |
Accession |
Description |
Interval |
E-value |
| recomb_RAD51 |
TIGR02239 |
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ... |
26-340 |
0e+00 |
|
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).
Pssm-ID: 274048 [Multi-domain] Cd Length: 316 Bit Score: 653.72 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 26 VSRLEQSGISSSDIKKLEDGGFHTVEAVAYAPKKELLNIKGISEAKADKILTEAAKMVPMGFTTATEFHQRRAEIIQIST 105
Cdd:TIGR02239 1 IEKLEGNGITAADIKKLQEAGLHTVESVAYAPKKQLLEIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRQEVIQLTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 106 GSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKAMYIDTEGTFRPERLLAVAERYGLVGSD 185
Cdd:TIGR02239 81 GSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERYGLNPED 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 186 VLDNVAYARAFNTDHQTQLLYQASAMMTESRYALLIVDSATALYRTDYSGRGELSARQGHLGRFLRMLLRLADEFGVAVV 265
Cdd:TIGR02239 161 VLDNVAYARAYNTDHQLQLLQQAAAMMSESRFALLIVDSATALYRTDFSGRGELSARQMHLARFLRSLQRLADEFGVAVV 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 347800669 266 ITNQVVAQVDGAA-MFSADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 340
Cdd:TIGR02239 241 ITNQVVAQVDGAGsMFAGDPKKPIGGNIMAHASTTRLSLRKGRGEQRICKIYDSPCLPESEAMFAIYEDGIGDPKE 316
|
|
| PTZ00035 |
PTZ00035 |
Rad51 protein; Provisional |
22-340 |
0e+00 |
|
Rad51 protein; Provisional
Pssm-ID: 185407 [Multi-domain] Cd Length: 337 Bit Score: 611.62 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 22 GPQPVSRLEQSGISSSDIKKLEDGGFHTVEAVAYAPKKELLNIKGISEAKADKILTEAAKMVPMGFTTATEFHQRRAEII 101
Cdd:PTZ00035 19 GFQEIEKLQSAGINAADIKKLKEAGICTVESVAYATKKDLCNIKGISEAKVEKIKEAASKLVPMGFISATEYLEARKNII 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 102 QISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKAMYIDTEGTFRPERLLAVAERYGL 181
Cdd:PTZ00035 99 RITTGSTQLDKLLGGGIETGSITELFGEFRTGKTQLCHTLCVTCQLPIEQGGGEGKVLYIDTEGTFRPERIVQIAERFGL 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 182 VGSDVLDNVAYARAFNTDHQTQLLYQASAMMTESRYALLIVDSATALYRTDYSGRGELSARQGHLGRFLRMLLRLADEFG 261
Cdd:PTZ00035 179 DPEDVLDNIAYARAYNHEHQMQLLSQAAAKMAEERFALLIVDSATALFRVDYSGRGELAERQQHLGKFLRALQKLADEFN 258
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 347800669 262 VAVVITNQVVAQVDGAAMFSADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 340
Cdd:PTZ00035 259 VAVVITNQVMADVDGASMFVADPKKPIGGHIIAHASTTRLSLRKGRGEQRICKIYDSPNLPESEAVFAISEGGIIDAKD 337
|
|
| PLN03186 |
PLN03186 |
DNA repair protein RAD51 homolog; Provisional |
22-340 |
0e+00 |
|
DNA repair protein RAD51 homolog; Provisional
Pssm-ID: 178728 [Multi-domain] Cd Length: 342 Bit Score: 604.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 22 GPQPVSRLEQSGISSSDIKKLEDGGFHTVEAVAYAPKKELLNIKGISEAKADKILTEAAKMVPMGFTTATEFHQRRAEII 101
Cdd:PLN03186 24 GPFPIEQLQASGIAALDIKKLKDAGIHTVESLAYAPKKDLLQIKGISEAKVEKILEAASKLVPLGFTTASQLHAQRQEII 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 102 QISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKAMYIDTEGTFRPERLLAVAERYGL 181
Cdd:PLN03186 104 QITTGSRELDKILEGGIETGSITEIYGEFRTGKTQLCHTLCVTCQLPLDQGGGEGKAMYIDTEGTFRPQRLIQIAERFGL 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 182 VGSDVLDNVAYARAFNTDHQTQLLYQASAMMTESRYALLIVDSATALYRTDYSGRGELSARQGHLGRFLRMLLRLADEFG 261
Cdd:PLN03186 184 NGADVLENVAYARAYNTDHQSELLLEAASMMAETRFALMIVDSATALYRTEFSGRGELSARQMHLGKFLRSLQRLADEFG 263
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 347800669 262 VAVVITNQVVAQVDGAAMFSADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 340
Cdd:PLN03186 264 VAVVITNQVVAQVDGSAFFAGPQLKPIGGNIMAHASTTRLALRKGRGENRICKVISSPCLPEAEARFSISSEGVTDVKD 342
|
|
| Rad51 |
cd19513 |
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ... |
103-337 |
0e+00 |
|
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.
Pssm-ID: 410921 [Multi-domain] Cd Length: 235 Bit Score: 548.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 103 ISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKAMYIDTEGTFRPERLLAVAERYGLV 182
Cdd:cd19513 1 ITTGSKELDKLLGGGIETGSITELFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERYGLN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 183 GSDVLDNVAYARAFNTDHQTQLLYQASAMMTESRYALLIVDSATALYRTDYSGRGELSARQGHLGRFLRMLLRLADEFGV 262
Cdd:cd19513 81 GEDVLDNVAYARAYNTDHQMQLLIQASAMMAESRYALLIVDSATALYRTDYSGRGELSARQMHLAKFLRMLQRLADEFGV 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 347800669 263 AVVITNQVVAQVDGAAMFSADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGD 337
Cdd:cd19513 161 AVVITNQVVAQVDGAAMFAGDPKKPIGGNIMAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAVFAITEDGIGD 235
|
|
| Rad51 |
pfam08423 |
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ... |
85-338 |
0e+00 |
|
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.
Pssm-ID: 462471 [Multi-domain] Cd Length: 255 Bit Score: 522.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 85 MGFTTATEFHQRRAEIIQISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKAMYIDTE 164
Cdd:pfam08423 1 MGFTTATELHQRRSELIQITTGSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLCVTCQLPLEMGGGEGKALYIDTE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 165 GTFRPERLLAVAERYGLVGSDVLDNVAYARAFNTDHQTQLLYQASAMMTESRYALLIVDSATALYRTDYSGRGELSARQG 244
Cdd:pfam08423 81 GTFRPERLVAIAERYGLDPEDVLDNVAYARAYNSEHQMQLLQQAAAMMSESRFALLIVDSATALYRTDFSGRGELAERQQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 245 HLGRFLRMLLRLADEFGVAVVITNQVVAQVDGAA-MFSADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPE 323
Cdd:pfam08423 161 HLAKFLRTLQRLADEFGVAVVITNQVVAQVDGAAgMFSGDPKKPIGGHIMAHASTTRLSLRKGRGEQRICKIYDSPCLPE 240
|
250
....*....|....*
gi 347800669 324 AEAMFAINADGVGDA 338
Cdd:pfam08423 241 SEAVFAIGSGGIIDP 255
|
|
| Rad51_DMC1_archRadA |
cd01123 |
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ... |
103-336 |
2.70e-162 |
|
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .
Pssm-ID: 410868 [Multi-domain] Cd Length: 234 Bit Score: 452.37 E-value: 2.70e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 103 ISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKAMYIDTEGTFRPERLLAVAERYGLV 182
Cdd:cd01123 1 ITTGSKELDKLLGGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDRGGGEGKAIYIDTEGTFRPERLRAIAQRFGLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 183 GSDVLDNVAYARAFNTDHQTQLLYQASAMMTESRYALLIVDSATALYRTDYSGRGELSARQGHLGRFLRMLLRLADEFGV 262
Cdd:cd01123 81 PDDVLDNVAYARAFNSDHQTQLLDQAAAMMVESRFKLLIVDSATALYRTDYSGRGELSARQMHLAKFLRMLQRLADEFGV 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 347800669 263 AVVITNQVVAQVDGAAMFSADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVG 336
Cdd:cd01123 161 AVVVTNQVVAQVDGAMMFAADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAVFAITADGVG 234
|
|
| recomb_DMC1 |
TIGR02238 |
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ... |
26-338 |
4.52e-150 |
|
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis.
Pssm-ID: 131292 [Multi-domain] Cd Length: 313 Bit Score: 424.58 E-value: 4.52e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 26 VSRLEQSGISSSDIKKLEDGGFHTVEAVAYAPKKELLNIKGISEAKADKILTEAAKMVPMGFTTATEFHQRRAEIIQIST 105
Cdd:TIGR02238 1 IDKLQAHGINAADIKKLKSAGICTVNGVIMTTRRALCKIKGLSEAKVDKIKEAASKIINPGFITAFEISQKRKKVLKITT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 106 GSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKAMYIDTEGTFRPERLLAVAERYGLVGSD 185
Cdd:TIGR02238 81 GSQALDGILGGGIESMSITEVFGEFRCGKTQLSHTLCVTAQLPREMGGGNGKVAYIDTEGTFRPDRIRAIAERFGVDPDA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 186 VLDNVAYARAFNTDHQTQLLYQASAMMTESRYALLIVDSATALYRTDYSGRGELSARQGHLGRFLRMLLRLADEFGVAVV 265
Cdd:TIGR02238 161 VLDNILYARAYTSEHQMELLDYLAAKFSEEPFRLLIVDSIMALFRVDFSGRGELSERQQKLAQMLSRLNKISEEFNVAVF 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 347800669 266 ITNQVVAQVDGAAMFSADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDA 338
Cdd:TIGR02238 241 VTNQVQADPGATMTFIADPKKPIGGHVLAHASTTRILLRKGRGEERVAKLYDSPDMPEAEASFQITEGGIADA 313
|
|
| PLN03187 |
PLN03187 |
meiotic recombination protein DMC1 homolog; Provisional |
26-340 |
5.77e-149 |
|
meiotic recombination protein DMC1 homolog; Provisional
Pssm-ID: 215620 [Multi-domain] Cd Length: 344 Bit Score: 423.03 E-value: 5.77e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 26 VSRLEQSGISSSDIKKLEDGGFHTVEAVAYAPKKELLNIKGISEAKADKILTEAAKMVPMGFTTATEFHQRRAEIIQIST 105
Cdd:PLN03187 31 IDKLISQGINAGDVKKLQDAGIYTCNGLMMHTKKNLTGIKGLSEAKVDKICEAAEKLLNQGFITGSDALLKRKSVVRITT 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 106 GSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKAMYIDTEGTFRPERLLAVAERYGLVGSD 185
Cdd:PLN03187 111 GSQALDELLGGGIETRCITEAFGEFRSGKTQLAHTLCVTTQLPTEMGGGNGKVAYIDTEGTFRPDRIVPIAERFGMDADA 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 186 VLDNVAYARAFNTDHQTQLLYQASAMMTESRYALLIVDSATALYRTDYSGRGELSARQGHLGRFLRMLLRLADEFGVAVV 265
Cdd:PLN03187 191 VLDNIIYARAYTYEHQYNLLLGLAAKMAEEPFRLLIVDSVIALFRVDFTGRGELAERQQKLAQMLSRLTKIAEEFNVAVY 270
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 347800669 266 ITNQVVAQVDGAAMFSaDPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD 340
Cdd:PLN03187 271 MTNQVIADPGGGMFIS-DPKKPAGGHVLAHAATIRLMLRKGKGEQRVCKVFDAPNLPEAEAEFQITSGGIMDAKD 344
|
|
| DMC1 |
cd19514 |
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ... |
103-337 |
2.81e-138 |
|
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.
Pssm-ID: 410922 [Multi-domain] Cd Length: 236 Bit Score: 391.72 E-value: 2.81e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 103 ISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKAMYIDTEGTFRPERLLAVAERYGLV 182
Cdd:cd19514 1 ISTGSTELDKLLGGGIESMSITEVFGEFRTGKTQLSHTLCVTAQLPGSMGGGGGKVAYIDTEGTFRPDRIRPIAERFGVD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 183 GSDVLDNVAYARAFNTDHQTQLLYQASAMMTES-RYALLIVDSATALYRTDYSGRGELSARQGHLGRFLRMLLRLADEFG 261
Cdd:cd19514 81 HDAVLDNILYARAYTSEHQMELLDYVAAKFHEEaVFRLLIIDSIMALFRVDFSGRGELAERQQKLAQMLSRLQKISEEYN 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 347800669 262 VAVVITNQVVAQVDGAAMFSADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGD 337
Cdd:cd19514 161 VAVFITNQVTADPGAAMTFQADPKKPIGGHILAHASTTRISLRKGRGEERIAKIYDSPDLPENEATFAITAGGIAD 236
|
|
| radA |
PRK04301 |
DNA repair and recombination protein RadA; Validated |
33-338 |
9.54e-137 |
|
DNA repair and recombination protein RadA; Validated
Pssm-ID: 235273 [Multi-domain] Cd Length: 317 Bit Score: 390.78 E-value: 9.54e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 33 GISSSDIKKLEDGGFHTVEAVAYAPKKELLNIKGISEAKADKILTEAAKMVPM-GFTTATEFHQRRAEIIQISTGSKELD 111
Cdd:PRK04301 13 GVGPATAEKLREAGYDTVEAIAVASPKELSEAAGIGESTAAKIIEAAREAADIgGFETALEVLERRKNVGKITTGSKELD 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 112 KLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKAMYIDTEGTFRPERLLAVAERYGLVGSDVLDNVA 191
Cdd:PRK04301 93 ELLGGGIETQSITEFYGEFGSGKTQICHQLAVNVQLPEEKGGLEGKAVYIDTEGTFRPERIEQMAEALGLDPDEVLDNIH 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 192 YARAFNTDHQTQLLYQASAMMTESR-YALLIVDSATALYRTDYSGRGELSARQGHLGRFLRMLLRLADEFGVAVVITNQV 270
Cdd:PRK04301 173 VARAYNSDHQMLLAEKAEELIKEGEnIKLVIVDSLTAHFRAEYVGRGNLAERQQKLNKHLHDLLRLADLYNAAVVVTNQV 252
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 347800669 271 VAQVDgaaMFSADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDA 338
Cdd:PRK04301 253 MARPD---AFFGDPTQPIGGHILGHTATFRIYLRKSKGNKRIARLVDSPHLPEGEAVFRITEEGIRDA 317
|
|
| recomb_radA |
TIGR02236 |
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA ... |
33-337 |
2.25e-120 |
|
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239), and archaeal RadB (TIGR02237). This protein is involved in DNA repair and recombination. The member from Pyrococcus horikoshii contains an intein. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 131290 [Multi-domain] Cd Length: 310 Bit Score: 349.04 E-value: 2.25e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 33 GISSSDIKKLEDGGFHTVEAVAYAPKKELLNIKGISEAKADKILTEAAKMVPMG-FTTATEFHQRRAEIIQISTGSKELD 111
Cdd:TIGR02236 6 GVGPATAEKLREAGYDTFEAIAVASPKELSEIAGISEGTAAKIIQAARKAADLGgFETADDVLERRKTIGKITTGSKELD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 112 KLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKAMYIDTEGTFRPERLLAVAERYGLVGSDVLDNVA 191
Cdd:TIGR02236 86 ELLGGGIETQAITEVFGEFGSGKTQICHQLAVNVQLPEEKGGLGGKAVYIDTENTFRPERIMQMAEARGLDPDEVLKNIY 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 192 YARAFNTDHQTQLLYQASAMMTE--SRYALLIVDSATALYRTDYSGRGELSARQGHLGRFLRMLLRLADEFGVAVVITNQ 269
Cdd:TIGR02236 166 VARAYNSNHQMLLVEKAEDLIKElnNPVKLLIVDSLTSHFRAEYVGRGALAERQQKLNKHLHDLLRLADLYNAAVVVTNQ 245
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 347800669 270 VVAQVDgaaMFSADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGD 337
Cdd:TIGR02236 246 VMARPD---AFFGDPTRPIGGHILGHAATFRVYLRKGKGDKRIARLVDSPHLPEGEAVFRITEKGIED 310
|
|
| archRadA |
cd19515 |
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ... |
103-337 |
2.11e-115 |
|
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)
Pssm-ID: 410923 [Multi-domain] Cd Length: 233 Bit Score: 333.56 E-value: 2.11e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 103 ISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKAMYIDTEGTFRPERLLAVAERYGLV 182
Cdd:cd19515 1 ISTGSKELDKLLGGGIETQAITEVFGEFGSGKTQLCHQLAVNVQLPPEEGGLNGKAVYIDTENTFRPERIMQMAKALGLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 183 GSDVLDNVAYARAFNTDHQTQLLYQASAMMTESR-YALLIVDSATALYRTDYSGRGELSARQGHLGRFLRMLLRLADEFG 261
Cdd:cd19515 81 PDEVLDNIYVARAYNSNHQMLLVEKAEDLIKEGNnIKLLIVDSLTSHFRAEYVGRGTLAERQQKLNKHLHDLHRLADLYN 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 347800669 262 VAVVITNQVVAQVDgaaMFSADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGD 337
Cdd:cd19515 161 IAVLVTNQVMAKPD---AFFGDPTQAIGGHILGHAATFRVYLRKGKGGKRIARLVDSPHLPEGEAVFRITEKGIED 233
|
|
| RecA-like |
cd01393 |
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
121-305 |
5.25e-50 |
|
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.
Pssm-ID: 410881 [Multi-domain] Cd Length: 185 Bit Score: 165.22 E-value: 5.25e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 121 GSITEMFGEFRTGKTQLCHTLAVTCQLpidqggGEGKAMYIDTEGTFRPERLLAVAERY---GLVGSDVLDNVAYARAFN 197
Cdd:cd01393 1 GKITEIYGPPGSGKTQLALQLAANALL------LGGGVVWIDTEGAFPPSRLVQILEASpssELELAEALSRLLYFRPPD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 198 TDHQTQLLYQASAMMTES-RYALLIVDSATALYRTDY----SGRGELSARQGHLGRFLRMLLRLADEFGVAVVITNQVVA 272
Cdd:cd01393 75 TLAHLLALDSLPESLFPPpNTSLVVVDSVSALFRKAFprggDGDSSSSLRARLLSQLARALQKLAAQFNLAVVVTNQVTT 154
|
170 180 190
....*....|....*....|....*....|...
gi 347800669 273 QVDGaaMFSADPKKPIGGNILAHASTTRLYLRK 305
Cdd:cd01393 155 KIRG--GSGASLVPPALGNTWEHSVSTRLLLYR 185
|
|
| XRCC3 |
cd19491 |
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ... |
110-322 |
1.27e-47 |
|
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410899 [Multi-domain] Cd Length: 250 Bit Score: 160.92 E-value: 1.27e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 110 LDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKAMYIDTEGTFRPERLLAVAERYGLVGSDV--- 186
Cdd:cd19491 1 LDELLGGGIPVGGITEIAGESGAGKTQLCLQLALTVQLPRELGGLGGGAVYICTESSFPSKRLQQLASSLPKRYHLEkak 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 187 --LDNVAYARAFNTDHQTQLL-YQASAMMTESRYALLIVDSATALYRTDY-SGRGELSARQGHLGRFLRMLLRLADEFGV 262
Cdd:cd19491 81 nfLDNIFVEHVADLETLEHCLnYQLPALLERGPIRLVVIDSIAALFRSEFdTSRSDLVERAKYLRRLADHLKRLADKYNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 263 AVVITNQVVAQVD-------------------GAAMFSADPKKPIGGNILAHASTTRLYLRKGRGET----------RIC 313
Cdd:cd19491 161 AVVVVNQVTDRFDsssdasglgvldylsqfssFSGGVSGNRKVPALGLTWANLVNTRLMLSRTPKRItdssaasisvRRL 240
|
....*....
gi 347800669 314 KIYDSPCLP 322
Cdd:cd19491 241 EVVFSPHLP 249
|
|
| radB |
PRK09361 |
DNA repair and recombination protein RadB; Provisional |
103-335 |
2.91e-46 |
|
DNA repair and recombination protein RadB; Provisional
Pssm-ID: 236482 [Multi-domain] Cd Length: 225 Bit Score: 156.56 E-value: 2.91e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 103 ISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCqlpIDQGGgegKAMYIDTEGtFRPERLLAVAeryglv 182
Cdd:PRK09361 5 LPTGCKMLDELLGGGFERGTITQIYGPPGSGKTNICLQLAVEA---AKNGK---KVIYIDTEG-LSPERFKQIA------ 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 183 GSD---VLDNVAYARAFNTDHQTQLLYQASAMMTESrYALLIVDSATALYRTDYSGRGELSARQGHLGRFLRMLLRLADE 259
Cdd:PRK09361 72 GEDfeeLLSNIIIFEPSSFEEQSEAIRKAEKLAKEN-VGLIVLDSATSLYRLELEDEEDNSKLNRELGRQLTHLLKLARK 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 347800669 260 FGVAVVITNQVVAQVDGAAMfsadpkKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAE-AMFAINADGV 335
Cdd:PRK09361 151 HDLAVVITNQVYSDIDSDGL------RPLGGHTLEHWSKTILRLEKFRNGKRRATLEKHRSRPEGEsAEFRITDRGI 221
|
|
| archRadB |
cd01394 |
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ... |
103-335 |
3.07e-45 |
|
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.
Pssm-ID: 410882 [Multi-domain] Cd Length: 216 Bit Score: 153.62 E-value: 3.07e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 103 ISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCqlpIDQGggeGKAMYIDTEGtFRPERLLAVAeryGLV 182
Cdd:cd01394 1 LSTGSKSLDSLLGGGVERGTITQIYGPPGSGKTNICLQLAVEA---AKQG---KKVVYIDTEG-LSPERFQQIA---GER 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 183 GSDVLDNVAYARAFNTDHQTQLLYQASAMMTESRYALLIVDSATALYRTDYSGRGELSARqghLGRFLRMLLRLADEFGV 262
Cdd:cd01394 71 FESIASNIIVFEPYSFDEQGVAIQEAEKLLKSDKVDLVVVDSATALYRLELGDDSEANRE---LSRQMSKLLSIARKYDI 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 347800669 263 AVVITNQVVAQVDgaamfsADPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAE-AMFAINADGV 335
Cdd:cd01394 148 PVVITNQVYSDID------DDRLKPVGGTLLEHWSKAIIRLEKSPPGLRRATLEKHRSRPEGQsAGFRITDRGI 215
|
|
| Rad51B |
cd19493 |
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
111-319 |
1.62e-38 |
|
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410901 [Multi-domain] Cd Length: 222 Bit Score: 136.30 E-value: 1.62e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 111 DKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKAMYIDTEGTFRPERLLAVAE-RYGLVGS----- 184
Cdd:cd19493 1 DTALAGGLPLGAITEITGASGSGKTQFALTLASSAAMPARKGGLDGGVLYIDTESKFSAERLAEIAEaRFPEAFSgfmee 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 185 -----DVLDNVAYARafnTDHQTQLLYQASAM---MTESRYALLIVDSATALYRTDYSG-RGELSARQGHLGRFLRMLLR 255
Cdd:cd19493 81 neraeEMLKRVAVVR---VTTLAQLLERLPNLeehILSSGVRLVVIDSIAALVRREFGGsDGEVTERHNALAREASSLKR 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 347800669 256 LADEFGVAVVITNQVVAQVDGAAMFSADPKKPIgGNILAHASTTRLYLRKGRG-ETRICKIYDSP 319
Cdd:cd19493 158 LAEEFRIAVLVTNQATTHFGDAGDGSSGVTAAL-GDAWAHAVNTRLRLERCLLqLRRVLEIVKSP 221
|
|
| recomb_radB |
TIGR02237 |
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB ... |
110-335 |
8.82e-38 |
|
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239) and DMC1 (TIGR02238), and archaeal RadA (TIGR02236).
Pssm-ID: 274047 [Multi-domain] Cd Length: 209 Bit Score: 134.08 E-value: 8.82e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 110 LDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTCqlpIDQGGgegKAMYIDTEGtFRPERLLAVAERyglVGSDVLDN 189
Cdd:TIGR02237 1 IDELLGGGVERGTITQIYGPPGSGKTNICMILAVNA---ARQGK---KVVYIDTEG-LSPERFKQIAED---RPERALSN 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 190 VAYARAFNTDHQTQLLYQASAMMTESRYALLIVDSATALYRTDYSgrGELSARQGHLGRFLRMLLRLADEFGVAVVITNQ 269
Cdd:TIGR02237 71 FIVFEVFDFDEQGVAIQKTSKFIDRDSASLVVVDSFTALYRLELS--DDRISRNRELARQLTLLLSLARKKNLAVVITNQ 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 347800669 270 VVAQVDGaamfsaDPKKPIGGNILAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGV 335
Cdd:TIGR02237 149 VYTDVNN------GTLRPLGGHLLEHWSKVILRLEKFRGRRLATLEKHRSRPEGESVYFRITDDGI 208
|
|
| Rad51C |
cd19492 |
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
121-319 |
1.72e-32 |
|
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51C, together with the other RAD51 paralogs, RAD51B, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site. Additionally, RAD51C acts as a mediator in the early steps of DNA damage signaling.
Pssm-ID: 410900 [Multi-domain] Cd Length: 172 Bit Score: 118.87 E-value: 1.72e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 121 GSITEMFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKAMYIDTEGTFrperllavaeryglvgsdvldNVAYARAFNTDH 200
Cdd:cd19492 1 GKITEICGVPGVGKTQLCMQLAVNVQIPKCFGGLAGEAIYIDTEGSF---------------------NIHYFRVHDYVE 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 201 QTQLLYQASAMMTE-SRYALLIVDSATALYRTDYSGrgeLSARQGHLGRFLRMLLRLADEFGVAVVITNQVVAQVDGAAM 279
Cdd:cd19492 60 LLALINSLPKFLEDhPKVKLIVVDSIAFPFRHDFDD---LAQRTRLLNGLAQLLHSLARQHNLAVVLTNQVTTKISEDGQ 136
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 347800669 280 FSAdpkKPIGGNILAHASTTRLYLRKGRGEtRICKIYDSP 319
Cdd:cd19492 137 SQL---VPALGESWSHACTTRLFLTWDEKQ-RFAHLYKSP 172
|
|
| RecA |
COG0468 |
RecA/RadA recombinase [Replication, recombination and repair]; |
95-306 |
1.62e-25 |
|
RecA/RadA recombinase [Replication, recombination and repair];
Pssm-ID: 440236 [Multi-domain] Cd Length: 351 Bit Score: 104.87 E-value: 1.62e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 95 QRRAEIIQISTGSKELDKLL-QGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLpidQGGGegkAMYIDTEGTFRPERll 173
Cdd:COG0468 36 KARQDVEVISTGSLALDIALgVGGLPRGRIVEIYGPESSGKTTLALHAIAEAQK---AGGI---AAFIDAEHALDPEY-- 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 174 avAERYGLvgsDVlDNVAYARAfntDHQTQLLYQASAMMTESRYALLIVDSATALYRtdysgRGELSARQG--HLG---- 247
Cdd:COG0468 108 --AKKLGV---DI-DNLLVSQP---DTGEQALEIAETLVRSGAVDLIVVDSVAALVP-----KAEIEGEMGdsHVGlqar 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 347800669 248 ---RFLRMLLRLADEFGVAVVITNQVVAQVDgaAMFsADPKKPIGGNILAHASTTRLYLRKG 306
Cdd:COG0468 174 lmsQALRKLTGAISKSNTTVIFINQLREKIG--VMF-GNPETTTGGNALKFYASVRLDIRRI 232
|
|
| Rad51D |
cd19489 |
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
115-305 |
3.10e-24 |
|
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410897 [Multi-domain] Cd Length: 209 Bit Score: 98.09 E-value: 3.10e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 115 QGGIETGSITEMFGEFRTGKTQLCHTLA--VTCQLPIdqgggegKAMYIDTEGTFRPERLLAVAE-RYGL--VGSDVLDN 189
Cdd:cd19489 1 GGGLRTGEITELVGESSSGKTQLCLTAAanVASRSGQ-------NVLYIDTKSSFSARRLAQILKsRAQDaeEIDKALQR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 190 VAYARAFNTDHQTQLLYQASAMM------TESRYALLIVDSATALYrtdYSGRGELSARQGH-----LGRFLRmllRLAD 258
Cdd:cd19489 74 IRVVRVFDPYELLDLLEELRNTLsqqqenLYSRLKLVIIDSLSALI---SPLLGGSKHSEGHallasLARLLK---KLAA 147
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 347800669 259 EFGVAVVITNQVVAQVDGAAMFSadpKKPIGGNILAHASTTRLYLRK 305
Cdd:cd19489 148 EYQIAVLVTNLTVRGGDGGQQGS---TKPALGEYWESVPSTRLLLSR 191
|
|
| XRCC2 |
cd19490 |
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells ... |
121-269 |
1.95e-14 |
|
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC2, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC3, helps recruit RAD51 to the break site.
Pssm-ID: 410898 [Multi-domain] Cd Length: 226 Bit Score: 71.61 E-value: 1.95e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 121 GSITEMFGEFRTGKTQLCHTLAVTCQLP-----IDQGGGEGKAMYIDTEGTFRPERLLAVAERY-------GLVGSDV-- 186
Cdd:cd19490 1 GDVIEITGPSGSGKTELLYHLAARCILPsswggVPLGGLEAAVVFIDTDGRFDILRLRSILEARiraaiqaANSSDDEed 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 187 --------LDNVAYARAFNTDHQT-------QLLYQASAmmtESRYALLIVDSATALYRTDYSGRGELSARQGHLGRFLR 251
Cdd:cd19490 81 veeiarecLQRLHIFRCHSSLQLLatllsleNYLLSLSA---NPELGLLLIDSISAFYWQDRFSAELARAAPLLQEAALR 157
|
170 180
....*....|....*....|..
gi 347800669 252 MLL----RLADEFGVAVVITNQ 269
Cdd:cd19490 158 AILrelrRLRRRFQLVVIATKQ 179
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
103-269 |
4.52e-12 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 64.55 E-value: 4.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 103 ISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVtcqlpidQGGGEG-KAMYIDTEgtFRPERLLAVAERYGL 181
Cdd:COG0467 2 VPTGIPGLDELLGGGLPRGSSTLLSGPPGTGKTTLALQFLA-------EGLRRGeKGLYVSFE--ESPEQLLRRAESLGL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 182 VGSDVLDN--VAYARAFNTDHQT---QLLYQASAMMTESRYALLIVDSATALYRtdysgrgeLSARQGHLGRFLRMLLRL 256
Cdd:COG0467 73 DLEEYIESglLRIIDLSPEELGLdleELLARLREAVEEFGAKRVVIDSLSGLLL--------ALPDPERLREFLHRLLRY 144
|
170
....*....|...
gi 347800669 257 ADEFGVAVVITNQ 269
Cdd:COG0467 145 LKKRGVTTLLTSE 157
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
113-311 |
3.87e-10 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 59.91 E-value: 3.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 113 LLQGGIETGSITEMFGEFRTGKT----QLChtLAVTCQLP-IDQGGGEGKAMYIDTEGTFRP--ERLLAVAERYGLVGSD 185
Cdd:COG3598 5 LVPGLLPEGGVTLLAGPPGTGKSflalQLA--AAVAAGGPwLGRRVPPGKVLYLAAEDDRGElrRRLKALGADLGLPFAD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 186 VLDNVAYARAFNTDHQTQLLYQASAMMTESRYALLIVDSATALYRTDysgrgELSARQghLGRFLRMLLRLADEFGVAVV 265
Cdd:COG3598 83 LDGRLRLLSLAGDLDDTDDLEALERAIEEEGPDLVVIDPLARVFGGD-----ENDAEE--MRAFLNPLDRLAERTGAAVL 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 347800669 266 I---TNQVVAQVDGAAMFSadpkkpiGGNILAHASTTRLYLRKGRGETR 311
Cdd:COG3598 156 LvhhTGKGGAGKDSGDRAR-------GSSALRGAARSVLVLSREKGEDL 197
|
|
| RecA |
cd00983 |
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
103-306 |
1.48e-09 |
|
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.
Pssm-ID: 410863 [Multi-domain] Cd Length: 235 Bit Score: 57.57 E-value: 1.48e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 103 ISTGSKELDKLL-QGGIETGSITEMFGEFRTGKTqlchTLAVTCQLPIDQGGgeGKAMYIDTEGTFRPErllaVAERYGL 181
Cdd:cd00983 5 IPTGSLSLDIALgIGGLPRGRIIEIYGPESSGKT----TLALHAIAEAQKLG--GTAAFIDAEHALDPE----YAKKLGV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 182 vgsdVLDNVAYARAfntDHQTQLLYQASAMMTESRYALLIVDSATALY-RTDYSGR-GE----LSARQghLGRFLRMLLR 255
Cdd:cd00983 75 ----DIDNLLVSQP---DTGEQALEIADTLIRSGAVDLIVVDSVAALVpKAEIEGEmGDshvgLQARL--MSQALRKLTG 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 347800669 256 LADEFGVAVVITNQVVAQVdgAAMFSAdPKKPIGGNILAHASTTRLYLRKG 306
Cdd:cd00983 146 SLSKSKTTVIFINQLREKI--GVMFGN-PETTTGGNALKFYASVRLDIRRI 193
|
|
| HHH_5 |
pfam14520 |
Helix-hairpin-helix domain; |
32-81 |
9.92e-08 |
|
Helix-hairpin-helix domain;
Pssm-ID: 434010 [Multi-domain] Cd Length: 57 Bit Score: 48.25 E-value: 9.92e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 347800669 32 SGISSSDIKKLEDGGFHTVEAVAYAPKKELLNIKGISEAKADKILTEAAK 81
Cdd:pfam14520 8 SGIGPKTALALLSAGIGTVEDLAEADVDELAEIPGIGEKTAQRIILELRD 57
|
|
| RecA |
pfam00154 |
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ... |
95-305 |
1.33e-07 |
|
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.
Pssm-ID: 425488 [Multi-domain] Cd Length: 262 Bit Score: 52.02 E-value: 1.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 95 QRRAEIIQISTGSKELDKLLQ-GGIETGSITEMFGEFRTGKTQLchTLAVTCQLpidQGGGeGKAMYIDTEGTFRPerll 173
Cdd:pfam00154 25 EKKLDVETISTGSLALDIALGiGGYPKGRIIEIYGPESSGKTTL--ALHAIAEA---QKAG-GTAAFIDAEHALDP---- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 174 avaeryglvgsdvldnvAYARAFNTDHQTQLLYQ----------ASAMMTESRYALLIVDSATALyrtdySGRGELSARQ 243
Cdd:pfam00154 95 -----------------VYAKKLGVDIDNLLVSQpdtgeqaleiADMLVRSGAIDLIVVDSVAAL-----VPKAEIEGEM 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 347800669 244 G--HLGRFLRML---LR----LADEFGVAVVITNQVVAQVdgAAMFsADPKKPIGGNILAHASTTRLYLRK 305
Cdd:pfam00154 153 GdsHVGLQARLMsqaLRkltgSISKSNTTVIFINQIREKI--GVMF-GNPETTTGGRALKFYASVRLDIRR 220
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
109-267 |
4.05e-07 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 49.69 E-value: 4.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 109 ELDKLLQGGIETGSITEMFGEFRTGKT----QLCHTLAVTCQLPIDQGGGE-GKAMYIDTEGTFR--PERLLAVAERYGL 181
Cdd:pfam13481 21 PRRWLIKGLLPAGGLGLLAGAPGTGKTtlalDLAAAVATGKPWLGGPRVPEqGKVLYVSAEGPADelRRRLRAAGADLDL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 182 VGS-DVLDNVAYARAFNTDHQTQLLYQASAMMTES-----RYALLIVDSATALYrtdysGRGELSARQghLGRFLRMLLR 255
Cdd:pfam13481 101 PARlLFLSLVESLPLFFLDRGGPLLDADVDALEAAleeveDPDLVVIDPLARAL-----GGDENSNSD--VGRLVKALDR 173
|
170
....*....|..
gi 347800669 256 LADEFGVAVVIT 267
Cdd:pfam13481 174 LARRTGATVLLV 185
|
|
| PRK06067 |
PRK06067 |
flagellar accessory protein FlaH; Validated |
103-267 |
6.07e-06 |
|
flagellar accessory protein FlaH; Validated
Pssm-ID: 180381 Cd Length: 234 Bit Score: 46.89 E-value: 6.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 103 ISTGSKELDKLLQGGIETGSITEMFGEFRTGKTqlchtlaVTCQLPIDQGGGEGKAM-YIDTEGTFRpeRLLAVAERYGL 181
Cdd:PRK06067 7 ISTGNEELDRKLGGGIPFPSLILIEGDHGTGKS-------VLSQQFVYGALKQGKKVyVITTENTSK--SYLKQMESVKI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 182 vgsDVLDNVA--YARAF---------NTDHQTQLLYQASAMMTESRYALLIVDSATALyrTDYsgrgelsARQGHLGRFL 250
Cdd:PRK06067 78 ---DISDFFLwgYLRIFplntegfewNSTLANKLLELIIEFIKSKREDVIIIDSLTIF--ATY-------AEEDDILNFL 145
|
170
....*....|....*..
gi 347800669 251 RMLLRLADEfGVAVVIT 267
Cdd:PRK06067 146 TEAKNLVDL-GKTILIT 161
|
|
| RadA_SMS_N |
cd01121 |
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ... |
99-270 |
8.45e-05 |
|
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.
Pssm-ID: 410866 [Multi-domain] Cd Length: 268 Bit Score: 43.67 E-value: 8.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 99 EIIQISTGSKELDKLLQGGIETGSITEMFGEFRTGKT----QLCHTLAvtcqlpidqgGGEGKAMYIDTEGTfrPERLLA 174
Cdd:cd01121 60 EEERISTGIGELDRVLGGGLVPGSVVLIGGDPGIGKStlllQVAARLA----------QRGGKVLYVSGEES--LSQIKL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 175 VAERYGLVGSDV-------LDNVAyarafntdhqtqllyqasAMMTESRYALLIVDSATALYRTDYSG--------RgEL 239
Cdd:cd01121 128 RAERLGLGSDNLyllaetnLEAIL------------------AEIEELKPSLVVIDSIQTVYSPELTSspgsvsqvR-EC 188
|
170 180 190
....*....|....*....|....*....|.
gi 347800669 240 SARqghlgrflrmLLRLADEFGVAVVITNQV 270
Cdd:cd01121 189 AAE----------LLRLAKETGIPVFLVGHV 209
|
|
| PRK09302 |
PRK09302 |
circadian clock protein KaiC; Reviewed |
89-268 |
1.11e-04 |
|
circadian clock protein KaiC; Reviewed
Pssm-ID: 236461 [Multi-domain] Cd Length: 509 Bit Score: 43.72 E-value: 1.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 89 TATEFHQRRAEIIqISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQL-CHTLAVTCQlpidqgGGEgKAMYIDTEGTf 167
Cdd:PRK09302 242 TAMRLTQRSSNER-ISSGVPDLDEMLGGGFFRGSIILVSGATGTGKTLLaSKFAEAACR------RGE-RCLLFAFEES- 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 347800669 168 rPERLLAVAERYGL-----VGSDVLDNVAyARAFNTDHQTQLLYQASAMMtESRYALLIVDSATALyrtdysgrgelsAR 242
Cdd:PRK09302 313 -RAQLIRNARSWGIdlekmEEKGLLKIIC-ARPESYGLEDHLIIIKREIE-EFKPSRVAIDPLSAL------------AR 377
|
170 180
....*....|....*....|....*....
gi 347800669 243 QGHLGRFLRMLLRLAD---EFGVAVVITN 268
Cdd:PRK09302 378 GGSLNEFRQFVIRLTDylkSEEITGLFTN 406
|
|
| MUS81 |
COG1948 |
ERCC4-type crossover junction endonuclease [Replication, recombination and repair]; |
47-75 |
3.81e-04 |
|
ERCC4-type crossover junction endonuclease [Replication, recombination and repair];
Pssm-ID: 441551 [Multi-domain] Cd Length: 214 Bit Score: 40.93 E-value: 3.81e-04
10 20
....*....|....*....|....*....
gi 347800669 47 FHTVEAVAYAPKKELLNIKGISEAKADKI 75
Cdd:COG1948 175 FGSVEAVFNASEEELMKVEGIGEKTAERI 203
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
103-181 |
4.13e-04 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 41.10 E-value: 4.13e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 347800669 103 ISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLAVTcQLPIDQgggegKAMYIDTEGTfrPERLLAVAERYGL 181
Cdd:cd01124 1 VKTGIPGLDELLGGGIPKGSVTLLTGGPGTGKTLFGLQFLYA-GAKNGE-----PGLFFTFEES--PERLLRNAKSFGW 71
|
|
| FlaH |
COG2874 |
Archaellum biogenesis ATPase ArlH/FlaH [Cell motility]; |
103-138 |
4.40e-04 |
|
Archaellum biogenesis ATPase ArlH/FlaH [Cell motility];
Pssm-ID: 442121 Cd Length: 230 Bit Score: 40.97 E-value: 4.40e-04
10 20 30
....*....|....*....|....*....|....*.
gi 347800669 103 ISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQLC 138
Cdd:COG2874 3 ISTGNDELDKRLGGGIPLGSLVLIEGENGTGKSVLS 38
|
|
| KaiC-like_C |
cd19487 |
C-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock ... |
103-137 |
4.81e-03 |
|
C-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410895 [Multi-domain] Cd Length: 219 Bit Score: 37.66 E-value: 4.81e-03
10 20 30
....*....|....*....|....*....|....*
gi 347800669 103 ISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQL 137
Cdd:cd19487 1 VSSGVPELDELLGGGLERGTSTLLIGPAGVGKSTL 35
|
|
| PRK08533 |
PRK08533 |
flagellar accessory protein FlaH; Reviewed |
99-142 |
5.26e-03 |
|
flagellar accessory protein FlaH; Reviewed
Pssm-ID: 181459 Cd Length: 230 Bit Score: 37.74 E-value: 5.26e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 347800669 99 EIIQISTGSKELDKLLQGGIETGSITEMFGEFRTGKTQLCHTLA 142
Cdd:PRK08533 2 ELAKIELSRDELHKRLGGGIPAGSLILIEGDESTGKSILSQRLA 45
|
|
| |
