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Conserved domains on  [gi|47086257|ref|NP_998056|]
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protein YIPF4 [Danio rerio]

Protein Classification

Yip1 family protein( domain architecture ID 229405)

Yip1 family protein localizes to the Golgi complex and may function in regulating membrane dynamics in the endomembrane system

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YIP1 super family cl46908
Rab GTPase interacting factor, Golgi membrane protein [Intracellular trafficking and secretion] ...
69-230 2.95e-13

Rab GTPase interacting factor, Golgi membrane protein [Intracellular trafficking and secretion];


The actual alignment was detected with superfamily member COG5080:

Pssm-ID: 481248  Cd Length: 227  Bit Score: 66.72  E-value: 2.95e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086257  69 PLLEELDIDLKDIYYKIRCVLMPmpsLGFNRQVVRDNPDFWGPLAVVLLFSMISIYGQFRVVSWIITIWIFGSLTIFLLA 148
Cdd:COG5080  60 PLLEELGINFGHIKSKSDDVLGP---FDNKAFDILADCDLWGPLIFILLYSLFLSLAGKSHFGYIYGISLFGTLSLHLLL 136
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086257 149 RVLGGE-VSYGQVLGVIGYSLLPLIVIAPLLLVIGGFEVVSTLIKLFGVFWAAYSAASLLVGD-EFKTKKPLLIYPIFLL 226
Cdd:COG5080 137 RLLGHKnISFFSTISILGYSLLPLVFNSLVSIILGRILILGYVVVALFLIWSTYAASGVLKSKlQLSNKRLLVVYPLLLF 216

                ....
gi 47086257 227 YIYF 230
Cdd:COG5080 217 YNVF 220
 
Name Accession Description Interval E-value
YIP1 COG5080
Rab GTPase interacting factor, Golgi membrane protein [Intracellular trafficking and secretion] ...
69-230 2.95e-13

Rab GTPase interacting factor, Golgi membrane protein [Intracellular trafficking and secretion];


Pssm-ID: 227412  Cd Length: 227  Bit Score: 66.72  E-value: 2.95e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086257  69 PLLEELDIDLKDIYYKIRCVLMPmpsLGFNRQVVRDNPDFWGPLAVVLLFSMISIYGQFRVVSWIITIWIFGSLTIFLLA 148
Cdd:COG5080  60 PLLEELGINFGHIKSKSDDVLGP---FDNKAFDILADCDLWGPLIFILLYSLFLSLAGKSHFGYIYGISLFGTLSLHLLL 136
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086257 149 RVLGGE-VSYGQVLGVIGYSLLPLIVIAPLLLVIGGFEVVSTLIKLFGVFWAAYSAASLLVGD-EFKTKKPLLIYPIFLL 226
Cdd:COG5080 137 RLLGHKnISFFSTISILGYSLLPLVFNSLVSIILGRILILGYVVVALFLIWSTYAASGVLKSKlQLSNKRLLVVYPLLLF 216

                ....
gi 47086257 227 YIYF 230
Cdd:COG5080 217 YNVF 220
Yip1 pfam04893
Yip1 domain; The Yip1 integral membrane domain contains four transmembrane alpha helices. The ...
97-233 8.89e-08

Yip1 domain; The Yip1 integral membrane domain contains four transmembrane alpha helices. The domain is characterized by the motifs DLYGP and GY. The Yip1 protein is a golgi protein involved in vesicular transport that interacts with GTPases.


Pssm-ID: 461468 [Multi-domain]  Cd Length: 173  Bit Score: 50.51  E-value: 8.89e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086257    97 FNRQVVRDNPDFWGPL----AVVLLFSMISIYGQFRVVSW-------------------IITIWIFGSLTIFLLARVLGG 153
Cdd:pfam04893  10 FFRRIREEPPDLLGPLlillLLLALLAALALLIGGTQVGWalsltqlsalavaigaligILLGLLILAALLYWLGRLFGG 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086257   154 EVSYGQVLGVIGYSLLPLIVIAPLLLVIGGFEVVSTLIKLFGVFWAAYSAASLLVG----DEFKTKKPLLIYPIFLLYIY 229
Cdd:pfam04893  90 RGSFKQTLAVAGYALLPLILGGLLSGLLPLLWLPLSLVGLLFGIWSLYLLYLGLKEahglSSKKAAALIAALLLLLLLLL 169

                  ....
gi 47086257   230 FLSL 233
Cdd:pfam04893 170 LVLL 173
 
Name Accession Description Interval E-value
YIP1 COG5080
Rab GTPase interacting factor, Golgi membrane protein [Intracellular trafficking and secretion] ...
69-230 2.95e-13

Rab GTPase interacting factor, Golgi membrane protein [Intracellular trafficking and secretion];


Pssm-ID: 227412  Cd Length: 227  Bit Score: 66.72  E-value: 2.95e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086257  69 PLLEELDIDLKDIYYKIRCVLMPmpsLGFNRQVVRDNPDFWGPLAVVLLFSMISIYGQFRVVSWIITIWIFGSLTIFLLA 148
Cdd:COG5080  60 PLLEELGINFGHIKSKSDDVLGP---FDNKAFDILADCDLWGPLIFILLYSLFLSLAGKSHFGYIYGISLFGTLSLHLLL 136
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086257 149 RVLGGE-VSYGQVLGVIGYSLLPLIVIAPLLLVIGGFEVVSTLIKLFGVFWAAYSAASLLVGD-EFKTKKPLLIYPIFLL 226
Cdd:COG5080 137 RLLGHKnISFFSTISILGYSLLPLVFNSLVSIILGRILILGYVVVALFLIWSTYAASGVLKSKlQLSNKRLLVVYPLLLF 216

                ....
gi 47086257 227 YIYF 230
Cdd:COG5080 217 YNVF 220
Yip1 pfam04893
Yip1 domain; The Yip1 integral membrane domain contains four transmembrane alpha helices. The ...
97-233 8.89e-08

Yip1 domain; The Yip1 integral membrane domain contains four transmembrane alpha helices. The domain is characterized by the motifs DLYGP and GY. The Yip1 protein is a golgi protein involved in vesicular transport that interacts with GTPases.


Pssm-ID: 461468 [Multi-domain]  Cd Length: 173  Bit Score: 50.51  E-value: 8.89e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086257    97 FNRQVVRDNPDFWGPL----AVVLLFSMISIYGQFRVVSW-------------------IITIWIFGSLTIFLLARVLGG 153
Cdd:pfam04893  10 FFRRIREEPPDLLGPLlillLLLALLAALALLIGGTQVGWalsltqlsalavaigaligILLGLLILAALLYWLGRLFGG 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 47086257   154 EVSYGQVLGVIGYSLLPLIVIAPLLLVIGGFEVVSTLIKLFGVFWAAYSAASLLVG----DEFKTKKPLLIYPIFLLYIY 229
Cdd:pfam04893  90 RGSFKQTLAVAGYALLPLILGGLLSGLLPLLWLPLSLVGLLFGIWSLYLLYLGLKEahglSSKKAAALIAALLLLLLLLL 169

                  ....
gi 47086257   230 FLSL 233
Cdd:pfam04893 170 LVLL 173
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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