general transcription factor IIH subunit 4 [Rattus norvegicus]
Protein Classification
general transcription factor IIH subunit TFB2 family; general transcription and DNA repair factor IIH subunit TFB2( domain architecture ID 10015720)
general transcription factor IIH subunit TFB2 family protein is a component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA| general transcription and DNA repair factor IIH subunit TFB2 is a component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II
Transcription factor tfb2; All proteins in this family are part of the TFIIH complex which is ...
19-461
0e+00
Transcription factor tfb2; All proteins in this family are part of the TFIIH complex which is involved in the initiation of transcription and nucleotide excision repair.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
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Pssm-ID: 273180 Cd Length: 448 Bit Score: 767.92 E-value: 0e+00
Transcription factor tfb2; All proteins in this family are part of the TFIIH complex which is ...
19-461
0e+00
Transcription factor tfb2; All proteins in this family are part of the TFIIH complex which is involved in the initiation of transcription and nucleotide excision repair.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273180 Cd Length: 448 Bit Score: 767.92 E-value: 0e+00
Transcription factor tfb2; All proteins in this family are part of the TFIIH complex which is ...
19-461
0e+00
Transcription factor tfb2; All proteins in this family are part of the TFIIH complex which is involved in the initiation of transcription and nucleotide excision repair.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273180 Cd Length: 448 Bit Score: 767.92 E-value: 0e+00
Transcription factor Tfb2 (p52) C-terminal domain; This is the C-terminal domain of ...
390-457
1.28e-28
Transcription factor Tfb2 (p52) C-terminal domain; This is the C-terminal domain of Transcription factor Tfb2 present in Saccharomyces cerevisiae. Tfb2 is referred to as p52 in humans. The interaction between p8-Tfb5 and p52-Tfb2 has a key role in the maintenance of the transcription factor TFIIH architecture and TFIIHs function in nucleotide-excision repair (NER) pathway. The C-terminal domain of Tfb2 is thought to have a crucial role in DNA repair.
Pssm-ID: 465701 [Multi-domain] Cd Length: 68 Bit Score: 107.27 E-value: 1.28e-28
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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