NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|42572001|ref|NP_974091|]
View 

Ubiquitin carboxyl-terminal hydrolase-related protein [Arabidopsis thaliana]

Protein Classification

DUF627 and DUF629 domain-containing protein( domain architecture ID 12057992)

protein containing domains DUF627, DUF629, and UCH

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
DUF629 pfam04780
Protein of unknown function (DUF629); This family represents a region of several plant ...
212-676 0e+00

Protein of unknown function (DUF629); This family represents a region of several plant proteins of unknown function. A C2H2 zinc finger is predicted in this region in some family members, but the spacing between the cysteine residues is not conserved throughout the family.


:

Pssm-ID: 428119  Cd Length: 464  Bit Score: 719.11  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    212 RLRSYWASMDVESKRNFMKVSIAKLTAYVERLYGRVGLDALEQVLDSARINRKWKFWMCRSCSQKFYYPKKFRSHLEQEH 291
Cdd:pfam04780    1 RLRSYWNSLDVKIKRDFLKVSISDLKSYVESVHGSEGRDVLSEVLSFARENKKWRFWVCRTCSEKFSSAEECKNHLEQEH 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    292 AAKFKPSTTKHMAQRVDEVWAGMISVAGWEPVDVVAAVEMIKTQLESVKEFV--YENGWSKNWPLAVDEERSKLLKELQS 369
Cdd:pfam04780   81 MANFKPKMQKDLPQRVDKEWAEMILNGSWEPVDTVAAVKMIKNRLKDVKAFVdyFKNGWSKDWPLADDEERSKLLKEIHL 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    370 LLLLFQERKILSCSIRDWMMQLTVKHLAQLEISEHTLsSKCRLVETPQSICFLECHELNQILDLLKRINCERVDGtELVS 449
Cdd:pfam04780  161 LLVSLCEHKILSCSHLDWVIQFTVEHLQKLEVSGSQL-LNCGLVETPQCICFLEAHELKQILKFLQELKCERSDG-DLVC 238
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    450 NATDSLCGRLRVKEKIEFDHEFSFMLLDKRLLRGKIASFDDEGIIDVCDHNVHYTKTHPQGDDTITWLLDYPLIDesFEF 529
Cdd:pfam04780  239 RAVDSLLDGTRVKEKIDLDGQFSCLLLDKRLLKGENAPFDDEGTINVFDPNVHYAKAQPQGDDILSWLLDYPSVD--KEF 316
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    530 PRSIRAHNLEICVAVLRAIHFTCATLGTKYAKKLQILNYDAALIDAKNLCILEDERRKNVPEDQWNTYASLLCDKCEERL 609
Cdd:pfam04780  317 PGPSREHNLDIWLAVLRALEKTFRTLGTLYEKKCEHLSYEEALQAVENLCLEEDERRENVQEDQWSTYASLLRKRCEELE 396
                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 42572001    610 VIDAGDSHTTKLCLCAVRDVLEKASHPTFEFSDLEDCMTLIHG-HKNLNDDTVLKSIDLLKSVVTNKV 676
Cdd:pfam04780  397 SVNDEDSLTTKLFLCAVRDVLKEAESPTFDQFDLEECLNGITSqLKDLSDDWVLKSILHLKDSVTEKV 464
UCH pfam00443
Ubiquitin carboxyl-terminal hydrolase;
848-1142 6.70e-45

Ubiquitin carboxyl-terminal hydrolase;


:

Pssm-ID: 425685 [Multi-domain]  Cd Length: 310  Bit Score: 164.92  E-value: 6.70e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    848 TRYNSALDMTLKALLNIKVLQEDLVHNRQLF---HGNLEEQVPCALKDFFSAVVSeQIKEDELYSYLLSNLLASLEEVHS 924
Cdd:pfam00443    6 LGNTCYMNSVLQSLFSIPPFRDYLLRISPLSedsRYNKDINLLCALRDLFKALQK-NSKSSSVSPKMFKKSLGKLNPDFS 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    925 LSS--DADEVVVTILEFLHWWKSP----EKESLVTRLFTLEEYERMRCTKCRRNPNYPEQSSYGIVMAANSIRNLKCAFG 998
Cdd:pfam00443   85 GYKqqDAQEFLLFLLDGLHEDLNGnhstENESLITDLFRGQLKSRLKCLSCGEVSETFEPFSDLSLPIPGDSAELKTASL 164
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    999 NMKFEEILTVIRMEDEMICDVKTGGCGKTNFVHHVLSRCPPIFTIVLE--------WEKNETETEISEtakalawEIDIS 1070
Cdd:pfam00443  165 QICFLQFSKLEELDDEEKYYCDKCGCKQDAIKQLKISRLPPVLIIHLKrfsynrstWEKLNTEVEFPL-------ELDLS 237
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001   1071 RLYEGLEEPNTN----YRLVSMI---GCGEEGEHIC--MAYKTNRWVSLRHEalleegvgnwkNVVRICGERRV---RPE 1138
Cdd:pfam00443  238 RYLAEELKPKTNnlqdYRLVAVVvhsGSLSSGHYIAyiKAYENNRWYKFDDE-----------KVTEVDEETAVlssSAY 306

                   ....
gi 42572001   1139 ILFY 1142
Cdd:pfam00443  307 ILFY 310
DUF627 pfam04781
Protein of unknown function (DUF627); This family represents the N-terminal region of several ...
20-125 2.77e-43

Protein of unknown function (DUF627); This family represents the N-terminal region of several plant proteins of unknown function.


:

Pssm-ID: 428120  Cd Length: 108  Bit Score: 152.77  E-value: 2.77e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001     20 LVHGYFAEGDYIKALEVIEDSISTRGKEKVPAMVHYLQGCFFYEQGTKTENSDMKFPFLLASVECFTEDCGVHAYSAIAL 99
Cdd:pfam04781    1 LAKDLFARGNHIKALEIIEDLISRHGEDKNSALLHRLQGTIFYKLAKKTENPDVKFTYLLGSVECFSEAVLLSHFCARSL 80
                           90       100
                   ....*....|....*....|....*.
gi 42572001    100 LELGKLIGSASFYKKALNIAKEGLSF 125
Cdd:pfam04781   81 FELASQLGSVLYYKKAVKKAKQGLSV 106
 
Name Accession Description Interval E-value
DUF629 pfam04780
Protein of unknown function (DUF629); This family represents a region of several plant ...
212-676 0e+00

Protein of unknown function (DUF629); This family represents a region of several plant proteins of unknown function. A C2H2 zinc finger is predicted in this region in some family members, but the spacing between the cysteine residues is not conserved throughout the family.


Pssm-ID: 428119  Cd Length: 464  Bit Score: 719.11  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    212 RLRSYWASMDVESKRNFMKVSIAKLTAYVERLYGRVGLDALEQVLDSARINRKWKFWMCRSCSQKFYYPKKFRSHLEQEH 291
Cdd:pfam04780    1 RLRSYWNSLDVKIKRDFLKVSISDLKSYVESVHGSEGRDVLSEVLSFARENKKWRFWVCRTCSEKFSSAEECKNHLEQEH 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    292 AAKFKPSTTKHMAQRVDEVWAGMISVAGWEPVDVVAAVEMIKTQLESVKEFV--YENGWSKNWPLAVDEERSKLLKELQS 369
Cdd:pfam04780   81 MANFKPKMQKDLPQRVDKEWAEMILNGSWEPVDTVAAVKMIKNRLKDVKAFVdyFKNGWSKDWPLADDEERSKLLKEIHL 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    370 LLLLFQERKILSCSIRDWMMQLTVKHLAQLEISEHTLsSKCRLVETPQSICFLECHELNQILDLLKRINCERVDGtELVS 449
Cdd:pfam04780  161 LLVSLCEHKILSCSHLDWVIQFTVEHLQKLEVSGSQL-LNCGLVETPQCICFLEAHELKQILKFLQELKCERSDG-DLVC 238
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    450 NATDSLCGRLRVKEKIEFDHEFSFMLLDKRLLRGKIASFDDEGIIDVCDHNVHYTKTHPQGDDTITWLLDYPLIDesFEF 529
Cdd:pfam04780  239 RAVDSLLDGTRVKEKIDLDGQFSCLLLDKRLLKGENAPFDDEGTINVFDPNVHYAKAQPQGDDILSWLLDYPSVD--KEF 316
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    530 PRSIRAHNLEICVAVLRAIHFTCATLGTKYAKKLQILNYDAALIDAKNLCILEDERRKNVPEDQWNTYASLLCDKCEERL 609
Cdd:pfam04780  317 PGPSREHNLDIWLAVLRALEKTFRTLGTLYEKKCEHLSYEEALQAVENLCLEEDERRENVQEDQWSTYASLLRKRCEELE 396
                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 42572001    610 VIDAGDSHTTKLCLCAVRDVLEKASHPTFEFSDLEDCMTLIHG-HKNLNDDTVLKSIDLLKSVVTNKV 676
Cdd:pfam04780  397 SVNDEDSLTTKLFLCAVRDVLKEAESPTFDQFDLEECLNGITSqLKDLSDDWVLKSILHLKDSVTEKV 464
UCH pfam00443
Ubiquitin carboxyl-terminal hydrolase;
848-1142 6.70e-45

Ubiquitin carboxyl-terminal hydrolase;


Pssm-ID: 425685 [Multi-domain]  Cd Length: 310  Bit Score: 164.92  E-value: 6.70e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    848 TRYNSALDMTLKALLNIKVLQEDLVHNRQLF---HGNLEEQVPCALKDFFSAVVSeQIKEDELYSYLLSNLLASLEEVHS 924
Cdd:pfam00443    6 LGNTCYMNSVLQSLFSIPPFRDYLLRISPLSedsRYNKDINLLCALRDLFKALQK-NSKSSSVSPKMFKKSLGKLNPDFS 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    925 LSS--DADEVVVTILEFLHWWKSP----EKESLVTRLFTLEEYERMRCTKCRRNPNYPEQSSYGIVMAANSIRNLKCAFG 998
Cdd:pfam00443   85 GYKqqDAQEFLLFLLDGLHEDLNGnhstENESLITDLFRGQLKSRLKCLSCGEVSETFEPFSDLSLPIPGDSAELKTASL 164
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    999 NMKFEEILTVIRMEDEMICDVKTGGCGKTNFVHHVLSRCPPIFTIVLE--------WEKNETETEISEtakalawEIDIS 1070
Cdd:pfam00443  165 QICFLQFSKLEELDDEEKYYCDKCGCKQDAIKQLKISRLPPVLIIHLKrfsynrstWEKLNTEVEFPL-------ELDLS 237
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001   1071 RLYEGLEEPNTN----YRLVSMI---GCGEEGEHIC--MAYKTNRWVSLRHEalleegvgnwkNVVRICGERRV---RPE 1138
Cdd:pfam00443  238 RYLAEELKPKTNnlqdYRLVAVVvhsGSLSSGHYIAyiKAYENNRWYKFDDE-----------KVTEVDEETAVlssSAY 306

                   ....
gi 42572001   1139 ILFY 1142
Cdd:pfam00443  307 ILFY 310
DUF627 pfam04781
Protein of unknown function (DUF627); This family represents the N-terminal region of several ...
20-125 2.77e-43

Protein of unknown function (DUF627); This family represents the N-terminal region of several plant proteins of unknown function.


Pssm-ID: 428120  Cd Length: 108  Bit Score: 152.77  E-value: 2.77e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001     20 LVHGYFAEGDYIKALEVIEDSISTRGKEKVPAMVHYLQGCFFYEQGTKTENSDMKFPFLLASVECFTEDCGVHAYSAIAL 99
Cdd:pfam04781    1 LAKDLFARGNHIKALEIIEDLISRHGEDKNSALLHRLQGTIFYKLAKKTENPDVKFTYLLGSVECFSEAVLLSHFCARSL 80
                           90       100
                   ....*....|....*....|....*.
gi 42572001    100 LELGKLIGSASFYKKALNIAKEGLSF 125
Cdd:pfam04781   81 FELASQLGSVLYYKKAVKKAKQGLSV 106
 
Name Accession Description Interval E-value
DUF629 pfam04780
Protein of unknown function (DUF629); This family represents a region of several plant ...
212-676 0e+00

Protein of unknown function (DUF629); This family represents a region of several plant proteins of unknown function. A C2H2 zinc finger is predicted in this region in some family members, but the spacing between the cysteine residues is not conserved throughout the family.


Pssm-ID: 428119  Cd Length: 464  Bit Score: 719.11  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    212 RLRSYWASMDVESKRNFMKVSIAKLTAYVERLYGRVGLDALEQVLDSARINRKWKFWMCRSCSQKFYYPKKFRSHLEQEH 291
Cdd:pfam04780    1 RLRSYWNSLDVKIKRDFLKVSISDLKSYVESVHGSEGRDVLSEVLSFARENKKWRFWVCRTCSEKFSSAEECKNHLEQEH 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    292 AAKFKPSTTKHMAQRVDEVWAGMISVAGWEPVDVVAAVEMIKTQLESVKEFV--YENGWSKNWPLAVDEERSKLLKELQS 369
Cdd:pfam04780   81 MANFKPKMQKDLPQRVDKEWAEMILNGSWEPVDTVAAVKMIKNRLKDVKAFVdyFKNGWSKDWPLADDEERSKLLKEIHL 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    370 LLLLFQERKILSCSIRDWMMQLTVKHLAQLEISEHTLsSKCRLVETPQSICFLECHELNQILDLLKRINCERVDGtELVS 449
Cdd:pfam04780  161 LLVSLCEHKILSCSHLDWVIQFTVEHLQKLEVSGSQL-LNCGLVETPQCICFLEAHELKQILKFLQELKCERSDG-DLVC 238
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    450 NATDSLCGRLRVKEKIEFDHEFSFMLLDKRLLRGKIASFDDEGIIDVCDHNVHYTKTHPQGDDTITWLLDYPLIDesFEF 529
Cdd:pfam04780  239 RAVDSLLDGTRVKEKIDLDGQFSCLLLDKRLLKGENAPFDDEGTINVFDPNVHYAKAQPQGDDILSWLLDYPSVD--KEF 316
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    530 PRSIRAHNLEICVAVLRAIHFTCATLGTKYAKKLQILNYDAALIDAKNLCILEDERRKNVPEDQWNTYASLLCDKCEERL 609
Cdd:pfam04780  317 PGPSREHNLDIWLAVLRALEKTFRTLGTLYEKKCEHLSYEEALQAVENLCLEEDERRENVQEDQWSTYASLLRKRCEELE 396
                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 42572001    610 VIDAGDSHTTKLCLCAVRDVLEKASHPTFEFSDLEDCMTLIHG-HKNLNDDTVLKSIDLLKSVVTNKV 676
Cdd:pfam04780  397 SVNDEDSLTTKLFLCAVRDVLKEAESPTFDQFDLEECLNGITSqLKDLSDDWVLKSILHLKDSVTEKV 464
UCH pfam00443
Ubiquitin carboxyl-terminal hydrolase;
848-1142 6.70e-45

Ubiquitin carboxyl-terminal hydrolase;


Pssm-ID: 425685 [Multi-domain]  Cd Length: 310  Bit Score: 164.92  E-value: 6.70e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    848 TRYNSALDMTLKALLNIKVLQEDLVHNRQLF---HGNLEEQVPCALKDFFSAVVSeQIKEDELYSYLLSNLLASLEEVHS 924
Cdd:pfam00443    6 LGNTCYMNSVLQSLFSIPPFRDYLLRISPLSedsRYNKDINLLCALRDLFKALQK-NSKSSSVSPKMFKKSLGKLNPDFS 84
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    925 LSS--DADEVVVTILEFLHWWKSP----EKESLVTRLFTLEEYERMRCTKCRRNPNYPEQSSYGIVMAANSIRNLKCAFG 998
Cdd:pfam00443   85 GYKqqDAQEFLLFLLDGLHEDLNGnhstENESLITDLFRGQLKSRLKCLSCGEVSETFEPFSDLSLPIPGDSAELKTASL 164
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001    999 NMKFEEILTVIRMEDEMICDVKTGGCGKTNFVHHVLSRCPPIFTIVLE--------WEKNETETEISEtakalawEIDIS 1070
Cdd:pfam00443  165 QICFLQFSKLEELDDEEKYYCDKCGCKQDAIKQLKISRLPPVLIIHLKrfsynrstWEKLNTEVEFPL-------ELDLS 237
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001   1071 RLYEGLEEPNTN----YRLVSMI---GCGEEGEHIC--MAYKTNRWVSLRHEalleegvgnwkNVVRICGERRV---RPE 1138
Cdd:pfam00443  238 RYLAEELKPKTNnlqdYRLVAVVvhsGSLSSGHYIAyiKAYENNRWYKFDDE-----------KVTEVDEETAVlssSAY 306

                   ....
gi 42572001   1139 ILFY 1142
Cdd:pfam00443  307 ILFY 310
DUF627 pfam04781
Protein of unknown function (DUF627); This family represents the N-terminal region of several ...
20-125 2.77e-43

Protein of unknown function (DUF627); This family represents the N-terminal region of several plant proteins of unknown function.


Pssm-ID: 428120  Cd Length: 108  Bit Score: 152.77  E-value: 2.77e-43
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42572001     20 LVHGYFAEGDYIKALEVIEDSISTRGKEKVPAMVHYLQGCFFYEQGTKTENSDMKFPFLLASVECFTEDCGVHAYSAIAL 99
Cdd:pfam04781    1 LAKDLFARGNHIKALEIIEDLISRHGEDKNSALLHRLQGTIFYKLAKKTENPDVKFTYLLGSVECFSEAVLLSHFCARSL 80
                           90       100
                   ....*....|....*....|....*.
gi 42572001    100 LELGKLIGSASFYKKALNIAKEGLSF 125
Cdd:pfam04781   81 FELASQLGSVLYYKKAVKKAKQGLSV 106
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH