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Conserved domains on  [gi|42571487|ref|NP_973834|]
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cytochrome c biogenesis protein family [Arabidopsis thaliana]

Protein Classification

cytochrome c-type biogenesis protein( domain architecture ID 10511314)

CcmH/CycL/Ccl2/NrfF family cytochrome c-type biogenesis protein is a membrane-anchored thiol-oxidoreductase that is essential in the maturation of c-type cytochromes, and is a possible subunit of a heme lyase

CATH:  1.10.8.640
PubMed:  8057830
SCOP:  4004325

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CcmH pfam03918
Cytochrome C biogenesis protein; Members of this family include NrfF, CcmH, CycL, Ccl2.
 14-132 4.28e-28

Cytochrome C biogenesis protein; Members of this family include NrfF, CcmH, CycL, Ccl2.


:

Pssm-ID: 461092  Cd Length: 143  Bit Score: 101.42  E-value: 4.28e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42571487    14 LDARARNISHNVRCTECGSQSIEDSQADIAILLRQLIRNEIGAGKTDKEIYSKLEDEFGETVLYAPKFDLQTAALWLTPV 93
Cdd:pfam03918  25 QEARARALSKELRCPVCQNQSIADSNAPLARDLRLEVREMLQAGKSDDEIVDYMVARYGDFVLYKPPFKGATLLLWLGPF 104

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 42571487    94 IIAGGTAAGIVYQKHRLRKNVDimalnliRGVPLTPKER 132
Cdd:pfam03918 105 LLLLLGALALFLRLRRRRRAAA-------TAAPLSAEEQ 136
 
Name Accession Description Interval E-value
CcmH pfam03918
Cytochrome C biogenesis protein; Members of this family include NrfF, CcmH, CycL, Ccl2.
 14-132 4.28e-28

Cytochrome C biogenesis protein; Members of this family include NrfF, CcmH, CycL, Ccl2.


Pssm-ID: 461092  Cd Length: 143  Bit Score: 101.42  E-value: 4.28e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42571487    14 LDARARNISHNVRCTECGSQSIEDSQADIAILLRQLIRNEIGAGKTDKEIYSKLEDEFGETVLYAPKFDLQTAALWLTPV 93
Cdd:pfam03918  25 QEARARALSKELRCPVCQNQSIADSNAPLARDLRLEVREMLQAGKSDDEIVDYMVARYGDFVLYKPPFKGATLLLWLGPF 104

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 42571487    94 IIAGGTAAGIVYQKHRLRKNVDimalnliRGVPLTPKER 132
Cdd:pfam03918 105 LLLLLGALALFLRLRRRRRAAA-------TAAPLSAEEQ 136
NrfF COG3088
Cytochrome c-type biogenesis protein CcmH/NrfF [Energy production and conversion, ...
 14-120 2.98e-27

Cytochrome c-type biogenesis protein CcmH/NrfF [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442322  Cd Length: 149  Bit Score: 99.49  E-value: 2.98e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42571487  14 LDARARNISHNVRCTECGSQSIEDSQADIAILLRQLIRNEIGAGKTDKEIYSKLEDEFGETVLYAPKFDLQTAALWLTPV 93
Cdd:COG3088  30 LEARARELSKELRCPVCQNQSIADSNAPLARDLRREVRERLAAGKSDEEIVDYMVARYGEFVLYKPPLKGATLLLWLGPF 109

                        90       100
                ....*....|....*....|....*..
gi 42571487  94 IIAGGTAAGIVYQKHRLRKNVDIMALN 120
Cdd:COG3088 110 LLLLLGLGVLVRFLRRRRAAAAAAPLS 136
CcmH_N cd16378
N-terminal domain of cytochrome c-type biogenesis protein CcmH and related proteins; ...
 14-79 3.57e-25

N-terminal domain of cytochrome c-type biogenesis protein CcmH and related proteins; Cytochrome c-type biogenesis protein CcmH is a membrane-anchored thiol-oxidoreductase that is essential in the maturation of c-type cytochromes. CcmH consists of an N-terminal catalytic domain with the active site CXXC motif and a C-terminal domain of unknown function which is predicted to contain TPR-like repeats. Other members of this family include NrfF, CycL, and Ccl2.


Pssm-ID: 319866  Cd Length: 67  Bit Score: 91.44  E-value: 3.57e-25
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 42571487  14 LDARARNISHNVRCTECGSQSIEDSQADIAILLRQLIRNEIGAGKTDKEIYSKLEDEFGETVLYAP 79
Cdd:cd16378   1 QEARARELAKELRCPVCQNQSLADSNAPIARDLRAEIREMLAEGKSDEEILDYLVARYGEFVLYAP 66
 
Name Accession Description Interval E-value
CcmH pfam03918
Cytochrome C biogenesis protein; Members of this family include NrfF, CcmH, CycL, Ccl2.
 14-132 4.28e-28

Cytochrome C biogenesis protein; Members of this family include NrfF, CcmH, CycL, Ccl2.


Pssm-ID: 461092  Cd Length: 143  Bit Score: 101.42  E-value: 4.28e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42571487    14 LDARARNISHNVRCTECGSQSIEDSQADIAILLRQLIRNEIGAGKTDKEIYSKLEDEFGETVLYAPKFDLQTAALWLTPV 93
Cdd:pfam03918  25 QEARARALSKELRCPVCQNQSIADSNAPLARDLRLEVREMLQAGKSDDEIVDYMVARYGDFVLYKPPFKGATLLLWLGPF 104

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 42571487    94 IIAGGTAAGIVYQKHRLRKNVDimalnliRGVPLTPKER 132
Cdd:pfam03918 105 LLLLLGALALFLRLRRRRRAAA-------TAAPLSAEEQ 136
NrfF COG3088
Cytochrome c-type biogenesis protein CcmH/NrfF [Energy production and conversion, ...
 14-120 2.98e-27

Cytochrome c-type biogenesis protein CcmH/NrfF [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442322  Cd Length: 149  Bit Score: 99.49  E-value: 2.98e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42571487  14 LDARARNISHNVRCTECGSQSIEDSQADIAILLRQLIRNEIGAGKTDKEIYSKLEDEFGETVLYAPKFDLQTAALWLTPV 93
Cdd:COG3088  30 LEARARELSKELRCPVCQNQSIADSNAPLARDLRREVRERLAAGKSDEEIVDYMVARYGEFVLYKPPLKGATLLLWLGPF 109

                        90       100
                ....*....|....*....|....*..
gi 42571487  94 IIAGGTAAGIVYQKHRLRKNVDIMALN 120
Cdd:COG3088 110 LLLLLGLGVLVRFLRRRRAAAAAAPLS 136
CcmH_N cd16378
N-terminal domain of cytochrome c-type biogenesis protein CcmH and related proteins; ...
 14-79 3.57e-25

N-terminal domain of cytochrome c-type biogenesis protein CcmH and related proteins; Cytochrome c-type biogenesis protein CcmH is a membrane-anchored thiol-oxidoreductase that is essential in the maturation of c-type cytochromes. CcmH consists of an N-terminal catalytic domain with the active site CXXC motif and a C-terminal domain of unknown function which is predicted to contain TPR-like repeats. Other members of this family include NrfF, CycL, and Ccl2.


Pssm-ID: 319866  Cd Length: 67  Bit Score: 91.44  E-value: 3.57e-25
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 42571487  14 LDARARNISHNVRCTECGSQSIEDSQADIAILLRQLIRNEIGAGKTDKEIYSKLEDEFGETVLYAP 79
Cdd:cd16378   1 QEARARELAKELRCPVCQNQSLADSNAPIARDLRAEIREMLAEGKSDEEILDYLVARYGEFVLYAP 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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