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Conserved domains on  [gi|42571031|ref|NP_973589|]
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B-box type zinc finger protein with CCT domain-containing protein [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CCT pfam06203
CCT motif; This short motif is found in a number of plant proteins. It is rich in basic amino ...
 356-398 1.06e-21

CCT motif; This short motif is found in a number of plant proteins. It is rich in basic amino acids and has been called a CCT motif after Co, Col and Toc1. The CCT motif is about 45 amino acids long and contains a putative nuclear localization signal within the second half of the CCT motif. Toc1 mutants have been identified in this region.


:

Pssm-ID: 461849  Cd Length: 44  Bit Score: 87.17  E-value: 1.06e-21
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 42571031   356 RDNAMQRYKEKKKTRRYDKTIRYETRKARAETRLRVKGRFVKA 398
Cdd:pfam06203   1 REEALLRYREKRKTRKFDKKIRYESRKALADKRPRVKGRFVKA 43
Bbox1_BBX-like cd19821
B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and ...
 11-54 3.49e-16

B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and similar proteins; The BBX family includes a group of zinc finger transcription factors that contain one or two B-box motifs, and sometimes also feature a CCT (CONSTANS, CO-like, and TOC1) domain. They play important roles in plant growth and development, including seedling photomorphogenesis, photoperiodic regulation of flowering, shade avoidance, and responses to biotic and abiotic stresses. Their B-box motifs show high sequence similarity with B-Box-type 1 zinc finger found in tripartite motif-containing proteins (TRIMs) and are involved in mediating transcriptional regulation and protein-protein interaction in plant signaling. The type 1 B-box (Bbox1) zinc finger is characterized by a C6H2 zinc-binding consensus motif; this family contains a modified motif, C3XC2H2, where X can be D, E, C or H.


:

Pssm-ID: 380879  Cd Length: 44  Bit Score: 71.95  E-value: 3.49e-16
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....
gi 42571031  11 ACEFCGERTAVLFCRADTAKLCLPCDQHVHSANLLSRKHVRSQI 54
Cdd:cd19821   1 LCDSCESAPAVVYCRADRASLCRACDAKVHSANKLASRHQRVPL 44
Bbox_SF super family cl00034
B-box-type zinc finger superfamily; The B-box-type zinc finger is a short zinc binding domain ...
 54-94 6.84e-08

B-box-type zinc finger superfamily; The B-box-type zinc finger is a short zinc binding domain of around 40 amino acid residues in length. It has been found in transcription factors, ribonucleoproteins and proto-oncoproteins, such as in TRIM (tripartite motif) proteins that consist of an N-terminal RING finger (originally called an A-box), followed by 1-2 B-box domains and a coiled-coil domain (also called RBCC for Ring, B-box, Coiled-Coil). The B-box-type zinc finger often presents in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interactions. Based on different consensus sequences and the spacing of the 7-8 zinc-binding residues, B-box-type zinc fingers can be divided into two groups, type 1 (Bbox1: C6H2) and type 2 (Bbox2: CHC3H2).


The actual alignment was detected with superfamily member cd19821:

Pssm-ID: 469587  Cd Length: 44  Bit Score: 48.45  E-value: 6.84e-08
                        10        20        30        40
                ....*....|....*....|....*....|....*....|.
gi 42571031  54 ICDNCSKEPVSVRCFTDNLVLCQECDWDVHGSCSSSATHER 94
Cdd:cd19821   1 LCDSCESAPAVVYCRADRASLCRACDAKVHSANKLASRHQR 41
 
Name Accession Description Interval E-value
CCT pfam06203
CCT motif; This short motif is found in a number of plant proteins. It is rich in basic amino ...
 356-398 1.06e-21

CCT motif; This short motif is found in a number of plant proteins. It is rich in basic amino acids and has been called a CCT motif after Co, Col and Toc1. The CCT motif is about 45 amino acids long and contains a putative nuclear localization signal within the second half of the CCT motif. Toc1 mutants have been identified in this region.


Pssm-ID: 461849  Cd Length: 44  Bit Score: 87.17  E-value: 1.06e-21
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 42571031   356 RDNAMQRYKEKKKTRRYDKTIRYETRKARAETRLRVKGRFVKA 398
Cdd:pfam06203   1 REEALLRYREKRKTRKFDKKIRYESRKALADKRPRVKGRFVKA 43
Bbox1_BBX-like cd19821
B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and ...
 11-54 3.49e-16

B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and similar proteins; The BBX family includes a group of zinc finger transcription factors that contain one or two B-box motifs, and sometimes also feature a CCT (CONSTANS, CO-like, and TOC1) domain. They play important roles in plant growth and development, including seedling photomorphogenesis, photoperiodic regulation of flowering, shade avoidance, and responses to biotic and abiotic stresses. Their B-box motifs show high sequence similarity with B-Box-type 1 zinc finger found in tripartite motif-containing proteins (TRIMs) and are involved in mediating transcriptional regulation and protein-protein interaction in plant signaling. The type 1 B-box (Bbox1) zinc finger is characterized by a C6H2 zinc-binding consensus motif; this family contains a modified motif, C3XC2H2, where X can be D, E, C or H.


Pssm-ID: 380879  Cd Length: 44  Bit Score: 71.95  E-value: 3.49e-16
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....
gi 42571031  11 ACEFCGERTAVLFCRADTAKLCLPCDQHVHSANLLSRKHVRSQI 54
Cdd:cd19821   1 LCDSCESAPAVVYCRADRASLCRACDAKVHSANKLASRHQRVPL 44
BBOX smart00336
B-Box-type zinc finger;
7-54 1.10e-08

B-Box-type zinc finger;


Pssm-ID: 197662 [Multi-domain]  Cd Length: 42  Bit Score: 50.41  E-value: 1.10e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 42571031      7 ESVVACEFCGERTAVLFCRADTAKLCLPCDQHVHsanllsRKHVRSQI 54
Cdd:smart00336   1 QRAPKCDSHGDEPAEFFCEECGALLCRTCDEAEH------RGHTVVLL 42
Bbox1_BBX-like cd19821
B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and ...
 54-94 6.84e-08

B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and similar proteins; The BBX family includes a group of zinc finger transcription factors that contain one or two B-box motifs, and sometimes also feature a CCT (CONSTANS, CO-like, and TOC1) domain. They play important roles in plant growth and development, including seedling photomorphogenesis, photoperiodic regulation of flowering, shade avoidance, and responses to biotic and abiotic stresses. Their B-box motifs show high sequence similarity with B-Box-type 1 zinc finger found in tripartite motif-containing proteins (TRIMs) and are involved in mediating transcriptional regulation and protein-protein interaction in plant signaling. The type 1 B-box (Bbox1) zinc finger is characterized by a C6H2 zinc-binding consensus motif; this family contains a modified motif, C3XC2H2, where X can be D, E, C or H.


Pssm-ID: 380879  Cd Length: 44  Bit Score: 48.45  E-value: 6.84e-08
                        10        20        30        40
                ....*....|....*....|....*....|....*....|.
gi 42571031  54 ICDNCSKEPVSVRCFTDNLVLCQECDWDVHGSCSSSATHER 94
Cdd:cd19821   1 LCDSCESAPAVVYCRADRASLCRACDAKVHSANKLASRHQR 41
zf-B_box pfam00643
B-box zinc finger;
50-83 4.63e-03

B-box zinc finger;


Pssm-ID: 459886 [Multi-domain]  Cd Length: 42  Bit Score: 34.76  E-value: 4.63e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 42571031    50 VRSQICDNCSKEPVSVRCFTDNLVLCQECDWDVH 83
Cdd:pfam00643   1 SKERLCPEHEEEPLTLYCNDCQELLCEECSVGEH 34
 
Name Accession Description Interval E-value
CCT pfam06203
CCT motif; This short motif is found in a number of plant proteins. It is rich in basic amino ...
 356-398 1.06e-21

CCT motif; This short motif is found in a number of plant proteins. It is rich in basic amino acids and has been called a CCT motif after Co, Col and Toc1. The CCT motif is about 45 amino acids long and contains a putative nuclear localization signal within the second half of the CCT motif. Toc1 mutants have been identified in this region.


Pssm-ID: 461849  Cd Length: 44  Bit Score: 87.17  E-value: 1.06e-21
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 42571031   356 RDNAMQRYKEKKKTRRYDKTIRYETRKARAETRLRVKGRFVKA 398
Cdd:pfam06203   1 REEALLRYREKRKTRKFDKKIRYESRKALADKRPRVKGRFVKA 43
Bbox1_BBX-like cd19821
B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and ...
 11-54 3.49e-16

B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and similar proteins; The BBX family includes a group of zinc finger transcription factors that contain one or two B-box motifs, and sometimes also feature a CCT (CONSTANS, CO-like, and TOC1) domain. They play important roles in plant growth and development, including seedling photomorphogenesis, photoperiodic regulation of flowering, shade avoidance, and responses to biotic and abiotic stresses. Their B-box motifs show high sequence similarity with B-Box-type 1 zinc finger found in tripartite motif-containing proteins (TRIMs) and are involved in mediating transcriptional regulation and protein-protein interaction in plant signaling. The type 1 B-box (Bbox1) zinc finger is characterized by a C6H2 zinc-binding consensus motif; this family contains a modified motif, C3XC2H2, where X can be D, E, C or H.


Pssm-ID: 380879  Cd Length: 44  Bit Score: 71.95  E-value: 3.49e-16
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....
gi 42571031  11 ACEFCGERTAVLFCRADTAKLCLPCDQHVHSANLLSRKHVRSQI 54
Cdd:cd19821   1 LCDSCESAPAVVYCRADRASLCRACDAKVHSANKLASRHQRVPL 44
BBOX smart00336
B-Box-type zinc finger;
7-54 1.10e-08

B-Box-type zinc finger;


Pssm-ID: 197662 [Multi-domain]  Cd Length: 42  Bit Score: 50.41  E-value: 1.10e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*...
gi 42571031      7 ESVVACEFCGERTAVLFCRADTAKLCLPCDQHVHsanllsRKHVRSQI 54
Cdd:smart00336   1 QRAPKCDSHGDEPAEFFCEECGALLCRTCDEAEH------RGHTVVLL 42
Bbox1_BBX-like cd19821
B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and ...
 54-94 6.84e-08

B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and similar proteins; The BBX family includes a group of zinc finger transcription factors that contain one or two B-box motifs, and sometimes also feature a CCT (CONSTANS, CO-like, and TOC1) domain. They play important roles in plant growth and development, including seedling photomorphogenesis, photoperiodic regulation of flowering, shade avoidance, and responses to biotic and abiotic stresses. Their B-box motifs show high sequence similarity with B-Box-type 1 zinc finger found in tripartite motif-containing proteins (TRIMs) and are involved in mediating transcriptional regulation and protein-protein interaction in plant signaling. The type 1 B-box (Bbox1) zinc finger is characterized by a C6H2 zinc-binding consensus motif; this family contains a modified motif, C3XC2H2, where X can be D, E, C or H.


Pssm-ID: 380879  Cd Length: 44  Bit Score: 48.45  E-value: 6.84e-08
                        10        20        30        40
                ....*....|....*....|....*....|....*....|.
gi 42571031  54 ICDNCSKEPVSVRCFTDNLVLCQECDWDVHGSCSSSATHER 94
Cdd:cd19821   1 LCDSCESAPAVVYCRADRASLCRACDAKVHSANKLASRHQR 41
Bbox1 cd19757
B-box-type 1 zinc finger (Bbox1); The B-box-type zinc finger is a short zinc binding domain of ...
 12-54 1.37e-05

B-box-type 1 zinc finger (Bbox1); The B-box-type zinc finger is a short zinc binding domain of around 40 amino acid residues in length. It has been found in transcription factors, ribonucleoproteins and proto-oncoproteins, such as in TRIM (tripartite motif) proteins that consist of an N-terminal RING finger (originally called an A-box), followed by 1-2 B-box domains and a coiled-coil domain (also called RBCC for Ring, B-box, Coiled-Coil). The B-box-type zinc finger often presents in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain, in functionally unrelated proteins, most likely mediating protein-protein interactions. Based on different consensus sequences and the spacing of the 7-8 zinc-binding residues, the B-box-type zinc fingers can be divided into two groups, type 1 (Bbox1: C6H2) and type 2 (Bbox2: CHC3H2). This family corresponds to the type 1 B-box (Bbox1).


Pssm-ID: 380815 [Multi-domain]  Cd Length: 44  Bit Score: 42.10  E-value: 1.37e-05
                        10        20        30        40
                ....*....|....*....|....*....|....*....|...
gi 42571031  12 CEFCGERTAVLFCRADTAKLCLPCDQHVHSANLLSRKHVRSQI 54
Cdd:cd19757   2 CDECEEREATVYCLECEEFLCDDCSDAIHRRGKLTRSHKLVPL 44
Bbox1 cd19757
B-box-type 1 zinc finger (Bbox1); The B-box-type zinc finger is a short zinc binding domain of ...
 54-94 7.19e-05

B-box-type 1 zinc finger (Bbox1); The B-box-type zinc finger is a short zinc binding domain of around 40 amino acid residues in length. It has been found in transcription factors, ribonucleoproteins and proto-oncoproteins, such as in TRIM (tripartite motif) proteins that consist of an N-terminal RING finger (originally called an A-box), followed by 1-2 B-box domains and a coiled-coil domain (also called RBCC for Ring, B-box, Coiled-Coil). The B-box-type zinc finger often presents in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain, in functionally unrelated proteins, most likely mediating protein-protein interactions. Based on different consensus sequences and the spacing of the 7-8 zinc-binding residues, the B-box-type zinc fingers can be divided into two groups, type 1 (Bbox1: C6H2) and type 2 (Bbox2: CHC3H2). This family corresponds to the type 1 B-box (Bbox1).


Pssm-ID: 380815 [Multi-domain]  Cd Length: 44  Bit Score: 39.79  E-value: 7.19e-05
                        10        20        30        40
                ....*....|....*....|....*....|....*....|.
gi 42571031  54 ICDNCSKEPVSVRCFTDNLVLCQECDWDVHGSCSSSATHER 94
Cdd:cd19757   1 LCDECEEREATVYCLECEEFLCDDCSDAIHRRGKLTRSHKL 41
Bbox1_HOIP cd19815
B-box-type 1 zinc finger found in HOIL-1-interacting protein (HOIP) and similar proteins; HOIP, ...
 12-54 1.38e-03

B-box-type 1 zinc finger found in HOIL-1-interacting protein (HOIP) and similar proteins; HOIP, also termed RING finger protein 31 (RNF31), or zinc in-between-RING-finger ubiquitin-associated domain protein, together with HOIL-1 and SHARPIN, forms the E3-ligase complex (also known as linear-ubiquitin-chain assembly complex LUBAC) that regulates NF-kappaB activity and apoptosis. It also interacts with the atypical mammalian orphan receptor DAX-1, trigger DAX-1 ubiquitination and stabilization, and participate in repressing steroidogenic gene expression. HOIP contains a B-box motif that shows high sequence similarity with B-Box-type 1 zinc finger found in tripartite motif-containing proteins (TRIMs). The type 1 B-box (Bbox1) zinc finger is characterized by a C6H2 zinc-binding consensus motif.


Pssm-ID: 380873  Cd Length: 43  Bit Score: 36.16  E-value: 1.38e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*
gi 42571031  12 CEFCGERTAVLFCRADTAKLCLPCDQ--HVHSANllsRKHVRSQI 54
Cdd:cd19815   2 CDLCGEAAASVFCASCEDKLCLSCDDlyHKHPAR---RSHHRQPI 43
zf-B_box pfam00643
B-box zinc finger;
50-83 4.63e-03

B-box zinc finger;


Pssm-ID: 459886 [Multi-domain]  Cd Length: 42  Bit Score: 34.76  E-value: 4.63e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 42571031    50 VRSQICDNCSKEPVSVRCFTDNLVLCQECDWDVH 83
Cdd:pfam00643   1 SKERLCPEHEEEPLTLYCNDCQELLCEECSVGEH 34
Bbox1_HOIP cd19815
B-box-type 1 zinc finger found in HOIL-1-interacting protein (HOIP) and similar proteins; HOIP, ...
 55-97 8.36e-03

B-box-type 1 zinc finger found in HOIL-1-interacting protein (HOIP) and similar proteins; HOIP, also termed RING finger protein 31 (RNF31), or zinc in-between-RING-finger ubiquitin-associated domain protein, together with HOIL-1 and SHARPIN, forms the E3-ligase complex (also known as linear-ubiquitin-chain assembly complex LUBAC) that regulates NF-kappaB activity and apoptosis. It also interacts with the atypical mammalian orphan receptor DAX-1, trigger DAX-1 ubiquitination and stabilization, and participate in repressing steroidogenic gene expression. HOIP contains a B-box motif that shows high sequence similarity with B-Box-type 1 zinc finger found in tripartite motif-containing proteins (TRIMs). The type 1 B-box (Bbox1) zinc finger is characterized by a C6H2 zinc-binding consensus motif.


Pssm-ID: 380873  Cd Length: 43  Bit Score: 33.85  E-value: 8.36e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|...
gi 42571031  55 CDNCSKEPVSVRCFTDNLVLCQECDwDVHGSCSSSATHERSAV 97
Cdd:cd19815   2 CDLCGEAAASVFCASCEDKLCLSCD-DLYHKHPARRSHHRQPI 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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