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Conserved domains on  [gi|41053895|ref|NP_956525|]
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WD repeat domain phosphoinositide-interacting protein 4 [Danio rerio]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 1000017)

WD40 repeat domain-containing protein folds into a beta-propeller structure and functions as a scaffold, providing a platform for the interaction and assembly of several proteins into a signalosome; similar to a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
Gene Ontology:  GO:0005515
PubMed:  10322433|8090199|30069656|29026209
SCOP:  4002744

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WD40 super family cl29593
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 6-262 2.42e-10

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


The actual alignment was detected with superfamily member cd00200:

Pssm-ID: 475233 [Multi-domain]  Cd Length: 289  Bit Score: 60.81  E-value: 2.42e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895   6 GVNSLQFNQDQS--CFCCAMETgVRIYNVEPLME----KGHLDheQVGSIALCSmlhRSNLLAVVGGGVnpkfseiSVLI 79
Cdd:cd00200  11 GVTCVAFSPDGKllATGSGDGT-IKVWDLETGELlrtlKGHTG--PVRDVAASA---DGTYLASGSSDK-------TIRL 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895  80 WDDarevrdPKDKLVLEFT-FTKPVLAVRMRHDkiiiilkNRIYVYSFPDNPVKLFEFDT-------RDNPKGLCDLCPS 151
Cdd:cd00200  78 WDL------ETGECVRTLTgHTSYVSSVAFSPD-------GRILSSSSRDKTIKVWDVETgkclttlRGHTDWVNSVAFS 144

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895 152 LEKQLLVFpGHKCGSLQLVDLSNTKPGTssapfTINAHQSEIACLALNQPGSVVASASRKGTlIRLFDTTTRDKLVELRR 231
Cdd:cd00200 145 PDGTFVAS-SSQDGTIKLWDLRTGKCVA-----TLTGHTGEVNSVAFSPDGEKLLSSSSDGT-IKLWDLSTGKCLGTLRG 217

                       250       260       270
                ....*....|....*....|....*....|.
gi 41053895 232 GTDPatLYCINFSHDSSFLCASSDKGTVHIF 262
Cdd:cd00200 218 HENG--VNSVAFSPDGYLLASGSEDGTIRVW 246
 
Name Accession Description Interval E-value
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 6-262 2.42e-10

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 60.81  E-value: 2.42e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895   6 GVNSLQFNQDQS--CFCCAMETgVRIYNVEPLME----KGHLDheQVGSIALCSmlhRSNLLAVVGGGVnpkfseiSVLI 79
Cdd:cd00200  11 GVTCVAFSPDGKllATGSGDGT-IKVWDLETGELlrtlKGHTG--PVRDVAASA---DGTYLASGSSDK-------TIRL 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895  80 WDDarevrdPKDKLVLEFT-FTKPVLAVRMRHDkiiiilkNRIYVYSFPDNPVKLFEFDT-------RDNPKGLCDLCPS 151
Cdd:cd00200  78 WDL------ETGECVRTLTgHTSYVSSVAFSPD-------GRILSSSSRDKTIKVWDVETgkclttlRGHTDWVNSVAFS 144

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895 152 LEKQLLVFpGHKCGSLQLVDLSNTKPGTssapfTINAHQSEIACLALNQPGSVVASASRKGTlIRLFDTTTRDKLVELRR 231
Cdd:cd00200 145 PDGTFVAS-SSQDGTIKLWDLRTGKCVA-----TLTGHTGEVNSVAFSPDGEKLLSSSSDGT-IKLWDLSTGKCLGTLRG 217

                       250       260       270
                ....*....|....*....|....*....|.
gi 41053895 232 GTDPatLYCINFSHDSSFLCASSDKGTVHIF 262
Cdd:cd00200 218 HENG--VNSVAFSPDGYLLASGSEDGTIRVW 246
WD40 COG2319
WD40 repeat [General function prediction only];
165-272 1.79e-09

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 58.77  E-value: 1.79e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895 165 GSLQLVDLSNTKPgtssaPFTINAHQSEIACLALNQPGSVVASASRKGTlIRLFDTTTRDKLVELRRGTDPAtlYCINFS 244
Cdd:COG2319 184 GTVRLWDLATGKL-----LRTLTGHTGAVRSVAFSPDGKLLASGSADGT-VRLWDLATGKLLRTLTGHSGSV--RSVAFS 255

                        90       100
                ....*....|....*....|....*...
gi 41053895 245 HDSSFLCASSDKGTVHIFALKDTKLNRR 272
Cdd:COG2319 256 PDGRLLASGSADGTVRLWDLATGELLRT 283
 
Name Accession Description Interval E-value
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 6-262 2.42e-10

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 60.81  E-value: 2.42e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895   6 GVNSLQFNQDQS--CFCCAMETgVRIYNVEPLME----KGHLDheQVGSIALCSmlhRSNLLAVVGGGVnpkfseiSVLI 79
Cdd:cd00200  11 GVTCVAFSPDGKllATGSGDGT-IKVWDLETGELlrtlKGHTG--PVRDVAASA---DGTYLASGSSDK-------TIRL 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895  80 WDDarevrdPKDKLVLEFT-FTKPVLAVRMRHDkiiiilkNRIYVYSFPDNPVKLFEFDT-------RDNPKGLCDLCPS 151
Cdd:cd00200  78 WDL------ETGECVRTLTgHTSYVSSVAFSPD-------GRILSSSSRDKTIKVWDVETgkclttlRGHTDWVNSVAFS 144

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895 152 LEKQLLVFpGHKCGSLQLVDLSNTKPGTssapfTINAHQSEIACLALNQPGSVVASASRKGTlIRLFDTTTRDKLVELRR 231
Cdd:cd00200 145 PDGTFVAS-SSQDGTIKLWDLRTGKCVA-----TLTGHTGEVNSVAFSPDGEKLLSSSSDGT-IKLWDLSTGKCLGTLRG 217

                       250       260       270
                ....*....|....*....|....*....|.
gi 41053895 232 GTDPatLYCINFSHDSSFLCASSDKGTVHIF 262
Cdd:cd00200 218 HENG--VNSVAFSPDGYLLASGSEDGTIRVW 246
WD40 COG2319
WD40 repeat [General function prediction only];
165-272 1.79e-09

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 58.77  E-value: 1.79e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895 165 GSLQLVDLSNTKPgtssaPFTINAHQSEIACLALNQPGSVVASASRKGTlIRLFDTTTRDKLVELRRGTDPAtlYCINFS 244
Cdd:COG2319 184 GTVRLWDLATGKL-----LRTLTGHTGAVRSVAFSPDGKLLASGSADGT-VRLWDLATGKLLRTLTGHSGSV--RSVAFS 255

                        90       100
                ....*....|....*....|....*...
gi 41053895 245 HDSSFLCASSDKGTVHIFALKDTKLNRR 272
Cdd:COG2319 256 PDGRLLASGSADGTVRLWDLATGELLRT 283
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 165-272 2.13e-09

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 57.73  E-value: 2.13e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895 165 GSLQLVDLSNTKPgtssaPFTINAHQSEIACLALNQPGSVVASASRKGTlIRLFDTTTRDKLVELRRGTDPATlyCINFS 244
Cdd:cd00200  73 KTIRLWDLETGEC-----VRTLTGHTSYVSSVAFSPDGRILSSSSRDKT-IKVWDVETGKCLTTLRGHTDWVN--SVAFS 144

                        90       100
                ....*....|....*....|....*...
gi 41053895 245 HDSSFLCASSDKGTVHIFALKDTKLNRR 272
Cdd:cd00200 145 PDGTFVASSSQDGTIKLWDLRTGKCVAT 172
WD40 COG2319
WD40 repeat [General function prediction only];
165-269 3.09e-09

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 58.00  E-value: 3.09e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895 165 GSLQLVDLSNTKPGTssapfTINAHQSEIACLALNQPGSVVASASRKGTlIRLFDTTTRDKLVELRRGTDPATlyCINFS 244
Cdd:COG2319 226 GTVRLWDLATGKLLR-----TLTGHSGSVRSVAFSPDGRLLASGSADGT-VRLWDLATGELLRTLTGHSGGVN--SVAFS 297

                        90       100
                ....*....|....*....|....*
gi 41053895 245 HDSSFLCASSDKGTVHIFALKDTKL 269
Cdd:COG2319 298 PDGKLLASGSDDGTVRLWDLATGKL 322
WD40 COG2319
WD40 repeat [General function prediction only];
165-269 1.76e-08

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 55.69  E-value: 1.76e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895 165 GSLQLVDLSNTKPGTssapfTINAHQSEIACLALNQPGSVVASASRKGTlIRLFDTTTRDKLVELRRGTDPatLYCINFS 244
Cdd:COG2319 142 GTVRLWDLATGKLLR-----TLTGHSGAVTSVAFSPDGKLLASGSDDGT-VRLWDLATGKLLRTLTGHTGA--VRSVAFS 213

                        90       100
                ....*....|....*....|....*
gi 41053895 245 HDSSFLCASSDKGTVHIFALKDTKL 269
Cdd:COG2319 214 PDGKLLASGSADGTVRLWDLATGKL 238
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 10-263 2.05e-08

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 54.65  E-value: 2.05e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895  10 LQFNQDQSCFCCAMETGVRIYNVEplmeKGHLDHEQVGSIA--LCSMLHRSNLLaVVGGGVNPkfseiSVLIWDdareVR 87
Cdd:cd00200  58 AASADGTYLASGSSDKTIRLWDLE----TGECVRTLTGHTSyvSSVAFSPDGRI-LSSSSRDK-----TIKVWD----VE 123

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895  88 DPKDKLVLEfTFTKPVLAVRMRHDKIIIilknriyVYSFPDNPVKLFEFDT-------RDNPKGLCDLCPSLEKQLLVFP 160
Cdd:cd00200 124 TGKCLTTLR-GHTDWVNSVAFSPDGTFV-------ASSSQDGTIKLWDLRTgkcvatlTGHTGEVNSVAFSPDGEKLLSS 195

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895 161 GHKcGSLQLVDLSNTKPGTssapfTINAHQSEIACLALNQPGSVVASASRKGTlIRLFDTTTRDKLVELRRGTDPATlyC 240
Cdd:cd00200 196 SSD-GTIKLWDLSTGKCLG-----TLRGHENGVNSVAFSPDGYLLASGSEDGT-IRVWDLRTGECVQTLSGHTNSVT--S 266

                       250       260
                ....*....|....*....|...
gi 41053895 241 INFSHDSSFLCASSDKGTVHIFA 263
Cdd:cd00200 267 LAWSPDGKRLASGSADGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
165-269 2.63e-08

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 54.92  E-value: 2.63e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895 165 GSLQLVDLSNTKPgtssaPFTINAHQSEIACLALNQPGSVVASASRKGTlIRLFDTTTRDKLVELRRGTDPatLYCINFS 244
Cdd:COG2319 100 GTVRLWDLATGLL-----LRTLTGHTGAVRSVAFSPDGKTLASGSADGT-VRLWDLATGKLLRTLTGHSGA--VTSVAFS 171

                        90       100
                ....*....|....*....|....*
gi 41053895 245 HDSSFLCASSDKGTVHIFALKDTKL 269
Cdd:COG2319 172 PDGKLLASGSDDGTVRLWDLATGKL 196
WD40 COG2319
WD40 repeat [General function prediction only];
165-269 3.97e-08

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 54.53  E-value: 3.97e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895 165 GSLQLVDLSNTKPGTssapfTINAHQSEIACLALNQPGSVVASASRKGTlIRLFDTTTRDKLVELRRGTDPatLYCINFS 244
Cdd:COG2319 268 GTVRLWDLATGELLR-----TLTGHSGGVNSVAFSPDGKLLASGSDDGT-VRLWDLATGKLLRTLTGHTGA--VRSVAFS 339

                        90       100
                ....*....|....*....|....*
gi 41053895 245 HDSSFLCASSDKGTVHIFALKDTKL 269
Cdd:COG2319 340 PDGKTLASGSDDGTVRLWDLATGEL 364
WD40 COG2319
WD40 repeat [General function prediction only];
165-266 6.21e-08

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 53.76  E-value: 6.21e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895 165 GSLQLVDLSNTKPgtssaPFTINAHQSEIACLALNQPGSVVASASRKGTlIRLFDTTTRDKLVELRRGTDPatLYCINFS 244
Cdd:COG2319 310 GTVRLWDLATGKL-----LRTLTGHTGAVRSVAFSPDGKTLASGSDDGT-VRLWDLATGELLRTLTGHTGA--VTSVAFS 381

                        90       100
                ....*....|....*....|..
gi 41053895 245 HDSSFLCASSDKGTVHIFALKD 266
Cdd:COG2319 382 PDGRTLASGSADGTVRLWDLAT 403
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 184-272 4.83e-06

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 47.71  E-value: 4.83e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895 184 FTINAHQSEIACLALNQPGSVVASASRKGTlIRLFDTTTRDKLVELRRGTDPatLYCINFSHDSSFLCASSDKGTVHIFA 263
Cdd:cd00200   3 RTLKGHTGGVTCVAFSPDGKLLATGSGDGT-IKVWDLETGELLRTLKGHTGP--VRDVAASADGTYLASGSSDKTIRLWD 79


                ....*....
gi 41053895 264 LKDTKLNRR 272
Cdd:cd00200  80 LETGECVRT 88
WD40 COG2319
WD40 repeat [General function prediction only];
178-269 2.02e-05

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 46.06  E-value: 2.02e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 41053895 178 GTSSAPFTINAHQSEIACLALNQPGSVVASASRKGTlIRLFDTTTRDKLVELRRGTDPATlyCINFSHDSSFLCASSDKG 257
Cdd:COG2319  66 AAGALLATLLGHTAAVLSVAFSPDGRLLASASADGT-VRLWDLATGLLLRTLTGHTGAVR--SVAFSPDGKTLASGSADG 142

                        90
                ....*....|..
gi 41053895 258 TVHIFALKDTKL 269
Cdd:COG2319 143 TVRLWDLATGKL 154
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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