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Conserved domains on  [gi|38016174|ref|NP_937857|]
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syntaphilin isoform a [Mus musculus]

Protein Classification

syntaphilin domain-containing protein( domain architecture ID 10633823)

syntaphilin domain-containing protein similar to Homo sapiens syntaphilin, a syntaxin-1 clamp that controls SNARE assembly, and syntabulin, a microtubule-associated protein implicated in syntaxin transport in neurons

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Syntaphilin pfam15290
Golgi-localized syntaxin-1-binding clamp; Syntaphilin or Syntabulin is a family of eukaryotic ...
 51-362 5.75e-169

Golgi-localized syntaxin-1-binding clamp; Syntaphilin or Syntabulin is a family of eukaryotic proteins. Syntaphilin binds to syntaxin-1 thereby inhibiting SNARE complex formation by absorbing free syntaxin-1. So it is a syntaxin-1 clamp that controls SNARE assembly.


:

Pssm-ID: 464617 [Multi-domain]  Cd Length: 305  Bit Score: 479.62  E-value: 5.75e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174    51 RTSPPVSVRDAYGTSSLSSSSNSGSCKGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQ 130
Cdd:pfam15290   1 NQGSPVNNRDAYGPSSLSSSSNSGSCKGSDSSPTRRRSGRYHSCGDNHGIKPPNPEQYLTPLQQKEVTIRHLKTKLKESE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174   131 DRLQDRDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIRQLKQVIDTVKNNLIDKDKGLQKYFVDINIQNKKL 210
Cdd:pfam15290  81 NRLQDRETEIEELKSQLSRMREDWIEEECHRVEAQLALKEARKEIKQLKQVIETMKSSLAEKDKGIQKYFVDINIQNKKL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174   211 ETLLHSMEVAQNGVAKEEGTGESAGGSPARSLTRSSTYTKLSDPAVcGDRQPGDPSNTSAEDGADSGYVAADDTLSRTDA 290
Cdd:pfam15290 161 ESLLQSMELAQNGSLRDEGTLEFACDSPAKSLTRSSTYTKLSDQLA-AEENGLELEDQSAEEMADSGLLANDEMANRTDL 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174   291 leassllssgvdcgLEEASLHSSFNLGPRFPASNTYEKLL---CGMEAGVQV-----SCMQERAIQTDFVQYQPDLNTIL 362
Cdd:pfam15290 240 --------------LEEVFMSTAVEAGDLAPFSSTYEKLMgsqKSVEALPSCseekqQMVEEQAIQTDVVPYSPDLDTLL 305
 
Name Accession Description Interval E-value
Syntaphilin pfam15290
Golgi-localized syntaxin-1-binding clamp; Syntaphilin or Syntabulin is a family of eukaryotic ...
 51-362 5.75e-169

Golgi-localized syntaxin-1-binding clamp; Syntaphilin or Syntabulin is a family of eukaryotic proteins. Syntaphilin binds to syntaxin-1 thereby inhibiting SNARE complex formation by absorbing free syntaxin-1. So it is a syntaxin-1 clamp that controls SNARE assembly.


Pssm-ID: 464617 [Multi-domain]  Cd Length: 305  Bit Score: 479.62  E-value: 5.75e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174    51 RTSPPVSVRDAYGTSSLSSSSNSGSCKGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQ 130
Cdd:pfam15290   1 NQGSPVNNRDAYGPSSLSSSSNSGSCKGSDSSPTRRRSGRYHSCGDNHGIKPPNPEQYLTPLQQKEVTIRHLKTKLKESE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174   131 DRLQDRDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIRQLKQVIDTVKNNLIDKDKGLQKYFVDINIQNKKL 210
Cdd:pfam15290  81 NRLQDRETEIEELKSQLSRMREDWIEEECHRVEAQLALKEARKEIKQLKQVIETMKSSLAEKDKGIQKYFVDINIQNKKL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174   211 ETLLHSMEVAQNGVAKEEGTGESAGGSPARSLTRSSTYTKLSDPAVcGDRQPGDPSNTSAEDGADSGYVAADDTLSRTDA 290
Cdd:pfam15290 161 ESLLQSMELAQNGSLRDEGTLEFACDSPAKSLTRSSTYTKLSDQLA-AEENGLELEDQSAEEMADSGLLANDEMANRTDL 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174   291 leassllssgvdcgLEEASLHSSFNLGPRFPASNTYEKLL---CGMEAGVQV-----SCMQERAIQTDFVQYQPDLNTIL 362
Cdd:pfam15290 240 --------------LEEVFMSTAVEAGDLAPFSSTYEKLMgsqKSVEALPSCseekqQMVEEQAIQTDVVPYSPDLDTLL 305
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 112-228 7.70e-07

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 50.31  E-value: 7.70e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174 112 LQQKEVCIRHLKARLKDTQDRLQDRDTEIDDLKTQLsrmqedwieeechrVEAQLALKEARKEIRQLKQVIDTVKnNLID 191
Cdd:COG1579  12 LQELDSELDRLEHRLKELPAELAELEDELAALEARL--------------EAAKTELEDLEKEIKRLELEIEEVE-ARIK 76

                        90       100       110
                ....*....|....*....|....*....|....*...
gi 38016174 192 KDKGLQKyfvdiNIQN-KKLETLLHSMEVAQNGVAKEE 228
Cdd:COG1579  77 KYEEQLG-----NVRNnKEYEALQKEIESLKRRISDLE 109
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 112-213 1.41e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.63  E-value: 1.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174   112 LQQKEVCIRHLKARLKDTQDRLQDRDTEIDDLKTQlsrMQEDWIEE--------ECHRVEAQLALKEARKEIRQLKQVID 183
Cdd:TIGR04523 269 LSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQ---KEQDWNKElkselknqEKKLEEIQNQISQNNKIISQLNEQIS 345

                          90       100       110
                  ....*....|....*....|....*....|
gi 38016174   184 TVKNNLIDKDKGLQKYFVDINIQNKKLETL 213
Cdd:TIGR04523 346 QLKKELTNSESENSEKQRELEEKQNEIEKL 375
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
119-229 1.99e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.28  E-value: 1.99e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174  119 IRHLKARLKDTQDRLQDRDTEIDDLKTQLSRMQEdwIEEEchrVEAQLALKEARKEIRQLKQVIDTVKNNLIDKDKGLQK 198
Cdd:PRK03918 254 KRKLEEKIRELEERIEELKKEIEELEEKVKELKE--LKEK---AEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEE 328

                         90       100       110
                 ....*....|....*....|....*....|.
gi 38016174  199 YFVDINIQNKKLETLLHSMEVAQNGVAKEEG 229
Cdd:PRK03918 329 RIKELEEKEERLEELKKKLKELEKRLEELEE 359
 
Name Accession Description Interval E-value
Syntaphilin pfam15290
Golgi-localized syntaxin-1-binding clamp; Syntaphilin or Syntabulin is a family of eukaryotic ...
 51-362 5.75e-169

Golgi-localized syntaxin-1-binding clamp; Syntaphilin or Syntabulin is a family of eukaryotic proteins. Syntaphilin binds to syntaxin-1 thereby inhibiting SNARE complex formation by absorbing free syntaxin-1. So it is a syntaxin-1 clamp that controls SNARE assembly.


Pssm-ID: 464617 [Multi-domain]  Cd Length: 305  Bit Score: 479.62  E-value: 5.75e-169
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174    51 RTSPPVSVRDAYGTSSLSSSSNSGSCKGSDSSPTPRRSMKYTLCSDNHGIKPPTPEQYLTPLQQKEVCIRHLKARLKDTQ 130
Cdd:pfam15290   1 NQGSPVNNRDAYGPSSLSSSSNSGSCKGSDSSPTRRRSGRYHSCGDNHGIKPPNPEQYLTPLQQKEVTIRHLKTKLKESE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174   131 DRLQDRDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIRQLKQVIDTVKNNLIDKDKGLQKYFVDINIQNKKL 210
Cdd:pfam15290  81 NRLQDRETEIEELKSQLSRMREDWIEEECHRVEAQLALKEARKEIKQLKQVIETMKSSLAEKDKGIQKYFVDINIQNKKL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174   211 ETLLHSMEVAQNGVAKEEGTGESAGGSPARSLTRSSTYTKLSDPAVcGDRQPGDPSNTSAEDGADSGYVAADDTLSRTDA 290
Cdd:pfam15290 161 ESLLQSMELAQNGSLRDEGTLEFACDSPAKSLTRSSTYTKLSDQLA-AEENGLELEDQSAEEMADSGLLANDEMANRTDL 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174   291 leassllssgvdcgLEEASLHSSFNLGPRFPASNTYEKLL---CGMEAGVQV-----SCMQERAIQTDFVQYQPDLNTIL 362
Cdd:pfam15290 240 --------------LEEVFMSTAVEAGDLAPFSSTYEKLMgsqKSVEALPSCseekqQMVEEQAIQTDVVPYSPDLDTLL 305
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 112-228 7.70e-07

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 50.31  E-value: 7.70e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174 112 LQQKEVCIRHLKARLKDTQDRLQDRDTEIDDLKTQLsrmqedwieeechrVEAQLALKEARKEIRQLKQVIDTVKnNLID 191
Cdd:COG1579  12 LQELDSELDRLEHRLKELPAELAELEDELAALEARL--------------EAAKTELEDLEKEIKRLELEIEEVE-ARIK 76

                        90       100       110
                ....*....|....*....|....*....|....*...
gi 38016174 192 KDKGLQKyfvdiNIQN-KKLETLLHSMEVAQNGVAKEE 228
Cdd:COG1579  77 KYEEQLG-----NVRNnKEYEALQKEIESLKRRISDLE 109
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 112-213 1.41e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.63  E-value: 1.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174   112 LQQKEVCIRHLKARLKDTQDRLQDRDTEIDDLKTQlsrMQEDWIEE--------ECHRVEAQLALKEARKEIRQLKQVID 183
Cdd:TIGR04523 269 LSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQ---KEQDWNKElkselknqEKKLEEIQNQISQNNKIISQLNEQIS 345

                          90       100       110
                  ....*....|....*....|....*....|
gi 38016174   184 TVKNNLIDKDKGLQKYFVDINIQNKKLETL 213
Cdd:TIGR04523 346 QLKKELTNSESENSEKQRELEEKQNEIEKL 375
BAR pfam03114
BAR domain; BAR domains are dimerization, lipid binding and curvature sensing modules found in ...
 149-226 1.78e-04

BAR domain; BAR domains are dimerization, lipid binding and curvature sensing modules found in many different protein families. A BAR domain with an additional N-terminal amphipathic helix (an N-BAR) can drive membrane curvature. These N-BAR domains are found in amphiphysin, endophilin, BRAP and Nadrin. BAR domains are also frequently found alongside domains that determine lipid specificity, like pfam00169 and pfam00787 domains in beta centaurins and sorting nexins respectively.


Pssm-ID: 460810 [Multi-domain]  Cd Length: 235  Bit Score: 43.09  E-value: 1.78e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 38016174   149 RMQEDWieEECHRVEAQLALKEARKEIRQ-LKQVIDTVKNNLIDKDKGLQKYFVDINIQNKKLETLLHSMEVAQNGVAK 226
Cdd:pfam03114  80 AGKDLG--EDSSFGKALEDYGEALKRLAQlLEQLDDRVETNFLDPLRNLLKEFKEIQKHRKKLERKRLDYDAAKTRVKK 156
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
119-229 1.99e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.28  E-value: 1.99e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174  119 IRHLKARLKDTQDRLQDRDTEIDDLKTQLSRMQEdwIEEEchrVEAQLALKEARKEIRQLKQVIDTVKNNLIDKDKGLQK 198
Cdd:PRK03918 254 KRKLEEKIRELEERIEELKKEIEELEEKVKELKE--LKEK---AEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEE 328

                         90       100       110
                 ....*....|....*....|....*....|.
gi 38016174  199 YFVDINIQNKKLETLLHSMEVAQNGVAKEEG 229
Cdd:PRK03918 329 RIKELEEKEERLEELKKKLKELEKRLEELEE 359
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
114-228 2.78e-04

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 43.35  E-value: 2.78e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174 114 QKEvcIRHLKARLKDTQDRLQDRDTEIDDLKTQLSRMQE--DWIEEECHRVEAQLA-----LKEARKEIRQLKQVIDTVK 186
Cdd:COG4372  44 QEE--LEQLREELEQAREELEQLEEELEQARSELEQLEEelEELNEQLQAAQAELAqaqeeLESLQEEAEELQEELEELQ 121

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*....
gi 38016174 187 N---NLIDKDKGLQ----KYFVDINIQNKKLETLLHSMEVAQNGVAKEE 228
Cdd:COG4372 122 KerqDLEQQRKQLEaqiaELQSEIAEREEELKELEEQLESLQEELAALE 170
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 113-227 1.42e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.54  E-value: 1.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174   113 QQKEVCIRHLKARLKDTQDRLQDRDTE-------IDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIRQLKQVIDTV 185
Cdd:TIGR04523 303 QKEQDWNKELKSELKNQEKKLEEIQNQisqnnkiISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSY 382

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 38016174   186 KN---NLIDKDKGLQKYFVDINIQNKKLETLLHSMEVAQNGVAKE 227
Cdd:TIGR04523 383 KQeikNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKE 427
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 138-213 2.95e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 40.39  E-value: 2.95e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 38016174   138 TEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIRQLKQVIDTVKNNLIDKDKglqkyfvDINIQNKKLETL 213
Cdd:TIGR04523 218 SQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQK-------ELEQNNKKIKEL 286
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 119-213 2.98e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 40.39  E-value: 2.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174   119 IRHLKARLKDTQDRLQDRDTEIDDLKTQLSRM--QEDWIEEECHRVEAQLalKEARKEIRQLKQVIDTVKNNLIDKDKGL 196
Cdd:TIGR04523  77 IKILEQQIKDLNDKLKKNKDKINKLNSDLSKInsEIKNDKEQKNKLEVEL--NKLEKQKKENKKNIDKFLTEIKKKEKEL 154

                          90
                  ....*....|....*..
gi 38016174   197 QKYFVDINIQNKKLETL 213
Cdd:TIGR04523 155 EKLNNKYNDLKKQKEEL 171
46 PHA02562
endonuclease subunit; Provisional
 122-239 3.13e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 40.38  E-value: 3.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174  122 LKARLKDTQDRLQDRDTEIDDLKTQLsRMQEDWIEE-----ECHRVEAQLALKEARKEIRQLKQVIDTVKNNLIDKDKGL 196
Cdd:PHA02562 172 NKDKIRELNQQIQTLDMKIDHIQQQI-KTYNKNIEEqrkknGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDI 250

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 38016174  197 QKYFVDINiqnkKLETLLH--SMEVAQngVAKEEGTGESAGGSPA 239
Cdd:PHA02562 251 EDPSAALN----KLNTAAAkiKSKIEQ--FQKVIKMYEKGGVCPT 289
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 106-221 5.20e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 39.36  E-value: 5.20e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174 106 EQYLTPLQQKevcIRHLKARLKDTQDRLQDRDTEIDDLKTQLSRMQEDWIEEECHRVEAQLALKEARKEIRQLKQVIDTV 185
Cdd:COG4942  26 EAELEQLQQE---IAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                        90       100       110
                ....*....|....*....|....*....|....*.
gi 38016174 186 KNNLIDKDKGLQKyfvdiNIQNKKLETLLHSMEVAQ 221
Cdd:COG4942 103 KEELAELLRALYR-----LGRQPPLALLLSPEDFLD 133
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 119-216 7.34e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 38.66  E-value: 7.34e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 38016174 119 IRHLKARLKDTQDRLQDRDTEIDDLKTQLSRMQEDWIEeechrveAQLALKEARKEIRQLKQVIDTVKNNLIDKDKGLQK 198
Cdd:COG3883  18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNE-------LQAELEALQAEIDKLQAEIAEAEAEIEERREELGE 90

                        90       100
                ....*....|....*....|.
gi 38016174 199 YFVDINIQ---NKKLETLLHS 216
Cdd:COG3883  91 RARALYRSggsVSYLDVLLGS 111
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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