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Conserved domains on  [gi|114205442|ref|NP_932121|]
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probable gluconokinase isoform a [Mus musculus]

Protein Classification

gluconokinase( domain architecture ID 10790049)

gluconokinase catalyzes the phosphoryl transfer from ATP to gluconate to form gluconate-6-phoshate

Gene Ontology:  GO:0046316|GO:0046177|GO:0005524
SCOP:  4003925

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 4-184 1.44e-81

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


:

Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 238.88  E-value: 1.44e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442   4 PGVLLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSDQDRIPWLCTLHDILLRDVALGQPVVLAC 83
Cdd:COG3265    1 PMVIVVMGVSGSGKSTVGQALAERLGWPFIDGDDFHPPANIAKMAAGIPLTDEDRAPWLEALADAIAAHLAAGEGAVLAC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442  84 SALKKTYRDILIRGGSDaplksddsakeplaggkLLVVYLCGSFDIIYGRLLQRKGHFMPPELLQSQFSILEPPSAPENF 163
Cdd:COG3265   81 SALKRSYRDRLREGNPD-----------------VRFVYLDGSRELIAERLAARKGHFMPASLLDSQFATLEPPGPDEDA 143

                        170       180
                 ....*....|....*....|.
gi 114205442 164 IQVSVDKSLPEITAAVMEALK 184
Cdd:COG3265  144 IVVDIDQPPEEIVAQILAALG 164
 
Name Accession Description Interval E-value
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 4-184 1.44e-81

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 238.88  E-value: 1.44e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442   4 PGVLLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSDQDRIPWLCTLHDILLRDVALGQPVVLAC 83
Cdd:COG3265    1 PMVIVVMGVSGSGKSTVGQALAERLGWPFIDGDDFHPPANIAKMAAGIPLTDEDRAPWLEALADAIAAHLAAGEGAVLAC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442  84 SALKKTYRDILIRGGSDaplksddsakeplaggkLLVVYLCGSFDIIYGRLLQRKGHFMPPELLQSQFSILEPPSAPENF 163
Cdd:COG3265   81 SALKRSYRDRLREGNPD-----------------VRFVYLDGSRELIAERLAARKGHFMPASLLDSQFATLEPPGPDEDA 143

                        170       180
                 ....*....|....*....|.
gi 114205442 164 IQVSVDKSLPEITAAVMEALK 184
Cdd:COG3265  144 IVVDIDQPPEEIVAQILAALG 164
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 6-168 5.85e-64

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 193.62  E-value: 5.85e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442   6 VLLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSDQDRIPWLCTLHDILLRDVAL-GQPVVLACS 84
Cdd:cd02021    1 IIVVMGVSGSGKSTVGKALAERLGAPFIDGDDLHPPANIAKMAAGIPLNDEDRWPWLQALTDALLAKLASaGEGVVVACS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442  85 ALKKTYRDILIRGgsdaplksddsakepLAGGKLLVVYLCGSFDIIYGRLLQRKGHFMPPELLQSQFSILEPPSA-PENF 163
Cdd:cd02021   81 ALKRIYRDILRGG---------------AANPRVRFVHLDGPREVLAERLAARKGHFMPADLLDSQFETLEPPGEdEEDV 145


                 ....*
gi 114205442 164 IQVSV 168
Cdd:cd02021  146 IVIDV 150
therm_gnt_kin TIGR01313
carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of ...
 7-184 2.79e-51

carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of proteins that includes thermoresistant and thermosensitve isozymes of gluconate kinase (gluconokinase) in E. coli and other related proteins; members of this family are often named by similarity to the thermostable isozyme. These proteins show homology to shikimate kinases and adenylate kinases but not to gluconate kinases from the FGGY family of carbohydrate kinases.


Pssm-ID: 273551  Cd Length: 163  Bit Score: 162.19  E-value: 2.79e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442    7 LLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSDQDRIPWLCTLHDILLRDVALGQPVVLACSAL 86
Cdd:TIGR01313   1 FVLMGVAGSGKSTIASALAHRLGAKFIEGDDLHPAANIEKMSAGIPLNDDDRWPWLQNLNDASTAAAAKNKVGIITCSAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442   87 KKTYRDILiRGgsdaplksddsakeplAGGKLLVVYLCGSFDIIYGRLLQRKGHFMPPELLQSQFSILEPPSAPE-NFIQ 165
Cdd:TIGR01313  81 KRHYRDIL-RE----------------AEPNLHFIYLSGDKDVILERMKARKGHFMKADMLESQFAALEEPLADEtDVLR 143

                         170
                  ....*....|....*....
gi 114205442  166 VSVDKSLPEITAAVMEALK 184
Cdd:TIGR01313 144 VDIDQPLEGVEEDCIAVVL 162
gntK PRK11545
gluconokinase;
10-184 4.32e-44

gluconokinase;


Pssm-ID: 236926  Cd Length: 163  Bit Score: 143.70  E-value: 4.32e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442  10 MGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSDQDRIPWLCTLHDILL-----RDVALgqpvvLACS 84
Cdd:PRK11545   1 MGVSGSGKSAVASEVAHQLHAAFLDGDFLHPRRNIEKMASGEPLNDDDRKPWLQALNDAAFamqrtNKVSL-----IVCS 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442  85 ALKKTYRDILiRGGSDaplksddsakeplaggKLLVVYLCGSFDIIYGRLLQRKGHFMPPELLQSQFSILEPPSAPENFI 164
Cdd:PRK11545  76 ALKKHYRDLL-REGNP----------------NLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADETDV 138

                        170       180
                 ....*....|....*....|.
gi 114205442 165 Q-VSVDKSLPEITAAVMEALK 184
Cdd:PRK11545 139 LvVDIDQPLEGVVASTIEVIK 159
SKI pfam01202
Shikimate kinase;
14-138 1.78e-12

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 61.83  E-value: 1.78e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442   14 GSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLS--DQDRIPWLCTLHDILLRdvalgQPVVLAC---SALKK 88
Cdd:pfam01202   2 GAGKSTIGRLLAKALGLPFIDTDEEIEKRTGMSIAEIFEEEgeEGFRRLESEVLKELLAE-----HGLVIATgggAVLSE 76

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 114205442   89 TYRDILIRGGsdaplksddsakeplaggklLVVYLCGSFDIIYGRLLQRK 138
Cdd:pfam01202  77 ENRDLLKERG--------------------IVIYLDAPLEVLLERLKRDK 106
 
Name Accession Description Interval E-value
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 4-184 1.44e-81

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 238.88  E-value: 1.44e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442   4 PGVLLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSDQDRIPWLCTLHDILLRDVALGQPVVLAC 83
Cdd:COG3265    1 PMVIVVMGVSGSGKSTVGQALAERLGWPFIDGDDFHPPANIAKMAAGIPLTDEDRAPWLEALADAIAAHLAAGEGAVLAC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442  84 SALKKTYRDILIRGGSDaplksddsakeplaggkLLVVYLCGSFDIIYGRLLQRKGHFMPPELLQSQFSILEPPSAPENF 163
Cdd:COG3265   81 SALKRSYRDRLREGNPD-----------------VRFVYLDGSRELIAERLAARKGHFMPASLLDSQFATLEPPGPDEDA 143

                        170       180
                 ....*....|....*....|.
gi 114205442 164 IQVSVDKSLPEITAAVMEALK 184
Cdd:COG3265  144 IVVDIDQPPEEIVAQILAALG 164
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 6-168 5.85e-64

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 193.62  E-value: 5.85e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442   6 VLLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSDQDRIPWLCTLHDILLRDVAL-GQPVVLACS 84
Cdd:cd02021    1 IIVVMGVSGSGKSTVGKALAERLGAPFIDGDDLHPPANIAKMAAGIPLNDEDRWPWLQALTDALLAKLASaGEGVVVACS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442  85 ALKKTYRDILIRGgsdaplksddsakepLAGGKLLVVYLCGSFDIIYGRLLQRKGHFMPPELLQSQFSILEPPSA-PENF 163
Cdd:cd02021   81 ALKRIYRDILRGG---------------AANPRVRFVHLDGPREVLAERLAARKGHFMPADLLDSQFETLEPPGEdEEDV 145


                 ....*
gi 114205442 164 IQVSV 168
Cdd:cd02021  146 IVIDV 150
therm_gnt_kin TIGR01313
carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of ...
 7-184 2.79e-51

carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of proteins that includes thermoresistant and thermosensitve isozymes of gluconate kinase (gluconokinase) in E. coli and other related proteins; members of this family are often named by similarity to the thermostable isozyme. These proteins show homology to shikimate kinases and adenylate kinases but not to gluconate kinases from the FGGY family of carbohydrate kinases.


Pssm-ID: 273551  Cd Length: 163  Bit Score: 162.19  E-value: 2.79e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442    7 LLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSDQDRIPWLCTLHDILLRDVALGQPVVLACSAL 86
Cdd:TIGR01313   1 FVLMGVAGSGKSTIASALAHRLGAKFIEGDDLHPAANIEKMSAGIPLNDDDRWPWLQNLNDASTAAAAKNKVGIITCSAL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442   87 KKTYRDILiRGgsdaplksddsakeplAGGKLLVVYLCGSFDIIYGRLLQRKGHFMPPELLQSQFSILEPPSAPE-NFIQ 165
Cdd:TIGR01313  81 KRHYRDIL-RE----------------AEPNLHFIYLSGDKDVILERMKARKGHFMKADMLESQFAALEEPLADEtDVLR 143

                         170
                  ....*....|....*....
gi 114205442  166 VSVDKSLPEITAAVMEALK 184
Cdd:TIGR01313 144 VDIDQPLEGVEEDCIAVVL 162
gntK PRK11545
gluconokinase;
10-184 4.32e-44

gluconokinase;


Pssm-ID: 236926  Cd Length: 163  Bit Score: 143.70  E-value: 4.32e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442  10 MGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSDQDRIPWLCTLHDILL-----RDVALgqpvvLACS 84
Cdd:PRK11545   1 MGVSGSGKSAVASEVAHQLHAAFLDGDFLHPRRNIEKMASGEPLNDDDRKPWLQALNDAAFamqrtNKVSL-----IVCS 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442  85 ALKKTYRDILiRGGSDaplksddsakeplaggKLLVVYLCGSFDIIYGRLLQRKGHFMPPELLQSQFSILEPPSAPENFI 164
Cdd:PRK11545  76 ALKKHYRDLL-REGNP----------------NLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADETDV 138

                        170       180
                 ....*....|....*....|.
gi 114205442 165 Q-VSVDKSLPEITAAVMEALK 184
Cdd:PRK11545 139 LvVDIDQPLEGVVASTIEVIK 159
idnK PRK09825
gluconokinase;
3-184 1.32e-41

gluconokinase;


Pssm-ID: 182097  Cd Length: 176  Bit Score: 137.85  E-value: 1.32e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442   3 APGVLLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLSDQDRIPWLCTLHDILLRDVALGQPVVLA 82
Cdd:PRK09825   2 AGESYILMGVSGSGKSLIGSKIAALFSAKFIDGDDLHPAKNIDKMSQGIPLTDEDRLPWLERLNDASYSLYKKNETGFIV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442  83 CSALKKTYRDILIRGGSDAPLksddsakeplaggkllvVYLCGSFDIIYGRLLQRKGHFMPPELLQSQFSILEPPSAPE- 161
Cdd:PRK09825  82 CSSLKKQYRDILRKSSPNVHF-----------------LWLDGDYETILARMQRRAGHFMPPDLLQSQFDALERPCADEh 144

                        170       180
                 ....*....|....*....|...
gi 114205442 162 NFIQVSVDKSLPEITAAVMEALK 184
Cdd:PRK09825 145 DIARIDVNHDIENVTEQCRQAVQ 167
SKI pfam01202
Shikimate kinase;
14-138 1.78e-12

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 61.83  E-value: 1.78e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442   14 GSGKSTVGALLASKLGWKFYDADDYHSEENRIKMAKGVPLS--DQDRIPWLCTLHDILLRdvalgQPVVLAC---SALKK 88
Cdd:pfam01202   2 GAGKSTIGRLLAKALGLPFIDTDEEIEKRTGMSIAEIFEEEgeEGFRRLESEVLKELLAE-----HGLVIATgggAVLSE 76

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 114205442   89 TYRDILIRGGsdaplksddsakeplaggklLVVYLCGSFDIIYGRLLQRK 138
Cdd:pfam01202  77 ENRDLLKERG--------------------IVIYLDAPLEVLLERLKRDK 106
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
6-178 3.67e-11

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 58.39  E-value: 3.67e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442   6 VLLVMGVSGSGKSTVGALLASKLGWKFYDADDyhsEENRIkmaKGVPLSDQDRIPWL-----CTLHDILLRDVALGQPVV 80
Cdd:COG0645    1 LILVCGLPGSGKSTLARALAERLGAVRLRSDV---VRKRL---FGAGLAPLERSPEAtartyARLLALARELLAAGRSVI 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442  81 LACSALKKTYRDiLIRggsdaplksdDSAKEplAGGKLLVVYLCGSFDIIYGRLLQRKGHFMPP----ELLQSQFSILEP 156
Cdd:COG0645   75 LDATFLRRAQRE-AFR----------ALAEE--AGAPFVLIWLDAPEEVLRERLEARNAEGGDSdatwEVLERQLAFEEP 141

                        170       180
                 ....*....|....*....|..
gi 114205442 157 PSAPENFIQVsVDKSLPEITAA 178
Cdd:COG0645  142 LTEDEGFLLV-VDTSGLEEALA 162
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 11-134 8.91e-11

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 57.18  E-value: 8.91e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442  11 GVSGSGKSTVGALLASKLGWKFYDADDYHseENRIKMAkgvplsdqdrIPWLCTLHD---------ILLRDVALGQPVVL 81
Cdd:cd00464    6 GMMGAGKTTVGRLLAKALGLPFVDLDELI--EQRAGMS----------IPEIFAEEGeegfrelerEVLLLLLTKENAVI 73

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 114205442  82 ACsalkktyrdilirGGSdAPLkSDDSAKEPLAGGklLVVYLCGSFDIIYGRL 134
Cdd:cd00464   74 AT-------------GGG-AVL-REENRRLLLENG--IVVWLDASPEELLERL 109
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 11-138 6.71e-10

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 55.13  E-value: 6.71e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442  11 GVSGSGKSTVGALLASKLGWKFYDADDYhseenrIKMAKGVPlsdqdrIPWLCTLH------DI---LLRDVALGQPVVL 81
Cdd:COG0703    5 GMMGAGKSTVGRLLAKRLGLPFVDTDAE------IEERAGMS------IPEIFAEEgeagfrELereVLAELLEEENAVI 72

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 114205442  82 ACsalkktyrdilirGGSdAPLkSDDSAKEPLAGGklLVVYLCGSFDIIYGRLLQRK 138
Cdd:COG0703   73 AT-------------GGG-AVL-SPENRELLKEHG--TVVYLDASPETLLERLRRDD 112
aroK PRK00131
shikimate kinase; Reviewed
 1-134 6.73e-10

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 55.20  E-value: 6.73e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442   1 MEAPGVLLVmGVSGSGKSTVGALLASKLGWKFYDADDYhseenrIKMAKGVPLSD--------------QDRIPWLCTLH 66
Cdd:PRK00131   2 LKGPNIVLI-GFMGAGKSTIGRLLAKRLGYDFIDTDHL------IEARAGKSIPEifeeegeaafreleEEVLAELLARH 74

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 114205442  67 DILlrdVALGQPVVLACSAlkktyRDILIRGGsdaplksddsakeplaggklLVVYLCGSFDIIYGRL 134
Cdd:PRK00131  75 NLV---ISTGGGAVLREEN-----RALLRERG--------------------TVVYLDASFEELLRRL 114
CMPK cd02020
Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine ...
 11-42 2.29e-07

Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor.


Pssm-ID: 238978 [Multi-domain]  Cd Length: 147  Bit Score: 47.87  E-value: 2.29e-07
                         10        20        30
                 ....*....|....*....|....*....|..
gi 114205442  11 GVSGSGKSTVGALLASKLGWKFYDADDYHSEE 42
Cdd:cd02020    6 GPAGSGKSTVAKLLAKKLGLPYLDTGGIRTEE 37
Pgk2 COG2074
2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase [Carbohydrate transport and ...
 1-31 6.49e-06

2-phosphoglycerate kinase/Mevalonate-3-phosphate 5-kinase [Carbohydrate transport and metabolism, Lipid transport and metabolism];


Pssm-ID: 441677  Cd Length: 207  Bit Score: 44.55  E-value: 6.49e-06
                         10        20        30
                 ....*....|....*....|....*....|.
gi 114205442   1 MEAPGVLLVMGVSGSGKSTVGALLASKLGWK 31
Cdd:COG2074    3 MKRPRIILIGGASGVGKSTIAAELARRLGIP 33
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 6-157 7.98e-06

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 43.45  E-value: 7.98e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442    6 VLLVMGVSGSGKSTVGALLASKLGWKFYDADDYHseeNRIKMAKGVPLSDQDRIPWLCT--LHDILLRDVALGQPVVLAC 83
Cdd:pfam13671   1 LILLVGLPGSGKSTLARRLLEELGAVRLSSDDER---KRLFGEGRPSISYYTDATDRTYerLHELARIALRAGRPVILDA 77

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 114205442   84 SALKKTYRDILIRGgsdaplksddsAKEplAGGKLLVVYLCGSFDIIYGRLLQRKGH-----FMPPELLQSQFSILEPP 157
Cdd:pfam13671  78 TNLRRDERARLLAL-----------ARE--YGVPVRIVVFEAPEEVLRERLAARARAggdpsDVPEEVLDRQKARFEPP 143
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
13-81 3.50e-05

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 42.51  E-value: 3.50e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114205442  13 SGSGKSTVGALLASKLGWKFYD-------ADDYH-SEENRIKMAKGVPLSDQDRIPWLCTLHDIL---LRDVALGQPVVL 81
Cdd:COG1102    9 PGSGGTTIAKRLAEKLGLPLYDgeilreaAKERGlSEEEFEKLDEKAPSLLYRDTAEEDEIDRALdkvIRELARKGNCVI 88
aroL PRK03731
shikimate kinase AroL;
7-38 3.79e-05

shikimate kinase AroL;


Pssm-ID: 235153 [Multi-domain]  Cd Length: 171  Bit Score: 42.24  E-value: 3.79e-05
                         10        20        30
                 ....*....|....*....|....*....|..
gi 114205442   7 LLVMGVSGSGKSTVGALLASKLGWKFYDADDY 38
Cdd:PRK03731   5 LFLVGARGCGKTTVGMALAQALGYRFVDTDQW 36
PRK06217 PRK06217
hypothetical protein; Validated
 7-38 3.81e-05

hypothetical protein; Validated


Pssm-ID: 168472  Cd Length: 183  Bit Score: 42.34  E-value: 3.81e-05
                         10        20        30
                 ....*....|....*....|....*....|..
gi 114205442   7 LLVMGVSGSGKSTVGALLASKLGWKFYDADDY 38
Cdd:PRK06217   4 IHITGASGSGTTTLGAALAERLDIPHLDTDDY 35
PRK13946 PRK13946
shikimate kinase; Provisional
 6-37 2.85e-04

shikimate kinase; Provisional


Pssm-ID: 184411 [Multi-domain]  Cd Length: 184  Bit Score: 39.91  E-value: 2.85e-04
                         10        20        30
                 ....*....|....*....|....*....|..
gi 114205442   6 VLLVmGVSGSGKSTVGALLASKLGWKFYDADD 37
Cdd:PRK13946  13 VVLV-GLMGAGKSTVGRRLATMLGLPFLDADT 43
Cmk COG0283
Cytidylate kinase [Nucleotide transport and metabolism];
11-34 3.78e-04

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440052 [Multi-domain]  Cd Length: 220  Bit Score: 39.62  E-value: 3.78e-04
                         10        20
                 ....*....|....*....|....
gi 114205442  11 GVSGSGKSTVGALLASKLGWKFYD 34
Cdd:COG0283    7 GPAGSGKSTVAKALAKRLGYHYLD 30
PRK13949 PRK13949
shikimate kinase; Provisional
 7-46 5.85e-04

shikimate kinase; Provisional


Pssm-ID: 140006 [Multi-domain]  Cd Length: 169  Bit Score: 38.56  E-value: 5.85e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 114205442   7 LLVMGVSGSGKSTVGALLASKLGWKFYDADDYhsEENRIK 46
Cdd:PRK13949   4 IFLVGYMGAGKTTLGKALARELGLSFIDLDFF--IENRFH 41
PLN02199 PLN02199
shikimate kinase
 7-36 7.42e-04

shikimate kinase


Pssm-ID: 177850 [Multi-domain]  Cd Length: 303  Bit Score: 39.30  E-value: 7.42e-04
                         10        20        30
                 ....*....|....*....|....*....|
gi 114205442   7 LLVMGVSGSGKSTVGALLASKLGWKFYDAD 36
Cdd:PLN02199 105 MYLVGMMGSGKTTVGKLMSKVLGYTFFDCD 134
Cytidylate_kin pfam02224
Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5 ...
 11-34 1.02e-03

Cytidylate kinase; Cytidylate kinase EC:2.7.4.14 catalyzes the phosphorylation of cytidine 5'-monophosphate (dCMP) to cytidine 5'-diphosphate (dCDP) in the presence of ATP or GTP.


Pssm-ID: 280401 [Multi-domain]  Cd Length: 211  Bit Score: 38.44  E-value: 1.02e-03
                          10        20
                  ....*....|....*....|....
gi 114205442   11 GVSGSGKSTVGALLASKLGWKFYD 34
Cdd:pfam02224   5 GPSGSGKSTVARILARKLGYKYLD 28
PRK04182 PRK04182
cytidylate kinase; Provisional
 9-37 1.18e-03

cytidylate kinase; Provisional


Pssm-ID: 235244 [Multi-domain]  Cd Length: 180  Bit Score: 37.86  E-value: 1.18e-03
                         10        20
                 ....*....|....*....|....*....
gi 114205442   9 VMGVSGSGKSTVGALLASKLGWKFYDADD 37
Cdd:PRK04182   5 ISGPPGSGKTTVARLLAEKLGLKHVSAGE 33
Fap7 COG1936
Broad-specificity NMP kinase [Nucleotide transport and metabolism];
6-43 3.92e-03

Broad-specificity NMP kinase [Nucleotide transport and metabolism];


Pssm-ID: 441539 [Multi-domain]  Cd Length: 173  Bit Score: 36.33  E-value: 3.92e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 114205442   6 VLLVMGVSGSGKSTVGALLASKLGWKFYDADDYHSEEN 43
Cdd:COG1936    2 RIAITGTPGTGKTTVAKLLAERLGLEVIHLNDLVKEEG 39
PRK13947 PRK13947
shikimate kinase; Provisional
 11-36 6.35e-03

shikimate kinase; Provisional


Pssm-ID: 184412 [Multi-domain]  Cd Length: 171  Bit Score: 35.84  E-value: 6.35e-03
                         10        20
                 ....*....|....*....|....*.
gi 114205442  11 GVSGSGKSTVGALLASKLGWKFYDAD 36
Cdd:PRK13947   8 GFMGTGKTTVGKRVATTLSFGFIDTD 33
CoaE COG0237
Dephospho-CoA kinase [Coenzyme transport and metabolism]; Dephospho-CoA kinase is part of the ...
 14-36 7.26e-03

Dephospho-CoA kinase [Coenzyme transport and metabolism]; Dephospho-CoA kinase is part of the Pathway/BioSystem: Pantothenate/CoA biosynthesis


Pssm-ID: 440007  Cd Length: 193  Bit Score: 35.81  E-value: 7.26e-03
                         10        20
                 ....*....|....*....|...
gi 114205442  14 GSGKSTVGALLAsKLGWKFYDAD 36
Cdd:COG0237   11 GSGKSTVARMFA-ELGAPVIDAD 32
PRK08154 PRK08154
anaerobic benzoate catabolism transcriptional regulator; Reviewed
 4-32 7.90e-03

anaerobic benzoate catabolism transcriptional regulator; Reviewed


Pssm-ID: 236167 [Multi-domain]  Cd Length: 309  Bit Score: 36.09  E-value: 7.90e-03
                         10        20
                 ....*....|....*....|....*....
gi 114205442   4 PGVLLVmGVSGSGKSTVGALLASKLGWKF 32
Cdd:PRK08154 134 RRIALI-GLRGAGKSTLGRMLAARLGVPF 161
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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