NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|32565247|ref|NP_871684|]
View 

4-hydroxybenzoate polyprenyltransferase, mitochondrial [Caenorhabditis elegans]

Protein Classification

UbiA prenyltransferase family protein( domain architecture ID 91)

UbiA prenyltransferase family protein, an aromatic prenyltransferase, plays an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PT_UbiA super family cl00337
UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA ...
 59-343 3.33e-132

UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


The actual alignment was detected with superfamily member PLN02809:

Pssm-ID: 469727  Cd Length: 289  Bit Score: 379.42  E-value: 3.33e-132
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247   59 PPNLKPYLQLMRVDKPIGTWLLYWPCTWSIAMATPAGQLPSIYMLSLFGAGAFLMRSAGCVINDLWDKDFDKKVERTKLR 138
Cdd:PLN02809   3 PPSLRPYAKLARLDKPIGTWLLAWPCMWSIALAAPPGSLPDLKMLALFGCGALLLRGAGCTINDLLDRDIDKKVERTKLR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  139 PLACGSLTEKQAIGLLAGLLSSSLAILLQLNWYSVAVGASSMALVVGYPLAKRFTYWPQFVLGATLNWSVLIAWAELGHF 218
Cdd:PLN02809  83 PIASGALTPFQGVGFLGAQLLLGLGILLQLNNYSRILGASSLLLVFTYPLMKRFTFWPQAFLGLTFNWGALLGWAAVKGS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  219 NDFGIFLPLYTATILHTVIYDTIYSHQDKADDIMIGVKSTALRLGADTKKWLSAFGVGTVASLTACGIASDQTWPYYVAL 298
Cdd:PLN02809 163 LDPAVVLPLYASGVCWTLVYDTIYAHQDKEDDLKVGVKSTALRFGDDTKLWLTGFGAASIGGLALSGYNAGLGWPYYAGL 242

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 32565247  299 AATTAQLGWQVGTVDIDNGSDCWDKFKSNSWMGIILFSGIVASTL 343
Cdd:PLN02809 243 AAAAGHLAWQIQTVDLSSRADCNRKFVSNKWFGAIVFAGIVLGKL 287
 
Name Accession Description Interval E-value
PLN02809 PLN02809
4-hydroxybenzoate nonaprenyltransferase
 59-343 3.33e-132

4-hydroxybenzoate nonaprenyltransferase


Pssm-ID: 178405  Cd Length: 289  Bit Score: 379.42  E-value: 3.33e-132
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247   59 PPNLKPYLQLMRVDKPIGTWLLYWPCTWSIAMATPAGQLPSIYMLSLFGAGAFLMRSAGCVINDLWDKDFDKKVERTKLR 138
Cdd:PLN02809   3 PPSLRPYAKLARLDKPIGTWLLAWPCMWSIALAAPPGSLPDLKMLALFGCGALLLRGAGCTINDLLDRDIDKKVERTKLR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  139 PLACGSLTEKQAIGLLAGLLSSSLAILLQLNWYSVAVGASSMALVVGYPLAKRFTYWPQFVLGATLNWSVLIAWAELGHF 218
Cdd:PLN02809  83 PIASGALTPFQGVGFLGAQLLLGLGILLQLNNYSRILGASSLLLVFTYPLMKRFTFWPQAFLGLTFNWGALLGWAAVKGS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  219 NDFGIFLPLYTATILHTVIYDTIYSHQDKADDIMIGVKSTALRLGADTKKWLSAFGVGTVASLTACGIASDQTWPYYVAL 298
Cdd:PLN02809 163 LDPAVVLPLYASGVCWTLVYDTIYAHQDKEDDLKVGVKSTALRFGDDTKLWLTGFGAASIGGLALSGYNAGLGWPYYAGL 242

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 32565247  299 AATTAQLGWQVGTVDIDNGSDCWDKFKSNSWMGIILFSGIVASTL 343
Cdd:PLN02809 243 AAAAGHLAWQIQTVDLSSRADCNRKFVSNKWFGAIVFAGIVLGKL 287
ubiA_proteo TIGR01474
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of ...
 62-343 4.88e-112

4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of integral membrane proteins that condenses para-hydroxybenzoate with any of several polyprenyldiphosphates. Heterologous expression studies suggest that for, many but not all members, the activity seen (e.g. octaprenyltransferase in E. coli) reflects available host isoprenyl pools rather than enzyme specificity. A fairly deep split by both clustering (UPGMA) and phylogenetics (NJ tree) separates this group (mostly Proteobacterial and mitochondrial), with several characterized members, from another group (mostly archaeal and Gram-positive bacterial) lacking characterized members. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 130539  Cd Length: 281  Bit Score: 328.12  E-value: 4.88e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247    62 LKPYLQLMRVDKPIGTWLLYWPCTWSIAMATPAGQLPSIYMLSLFGAGAFLMRSAGCVINDLWDKDFDKKVERTKLRPLA 141
Cdd:TIGR01474   1 LLPYAKLMRADKPIGTLLLLWPCLWSLLLAAQAGGIPPLYLLGLFTVGAILMRGAGCVINDIWDRDFDPQVERTKSRPLA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247   142 CGSLTEKQAIGLLAGLLSSSLAILLQLNWYSVAVGASSMALVVGYPLAKRFTYWPQFVLGATLNWSVLIAW-AELGHFND 220
Cdd:TIGR01474  81 SGAVSVRQAILFLLVQLLVALGVLLQLNPLTILLGVASLALVATYPFMKRITYWPQLVLGLAFGWGALMGWaAVTGDLST 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247   221 FGIFlpLYTATILHTVIYDTIYSHQDKADDIMIGVKSTALRLGADTKKWLSAFGVGTVASLTACGIASDQTWPYYVALAA 300
Cdd:TIGR01474 161 AAWV--LYLANILWTLGYDTIYAMQDKEDDIKIGVKSTALRFGDNTKPWLGGLYALMILLLALAGLIAGLGPVYYLGLAA 238

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 32565247   301 TTAQLGWQVGTVDIDNGSDCWDKFKSNSWMGIILFSGIVASTL 343
Cdd:TIGR01474 239 AALLLIRQIATLDIRDPENCLKLFKANNYVGLLLFAGIALGWL 281
PT_UbiA_COQ2 cd13959
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known ...
 69-341 6.68e-108

4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known as Coq2, catalyzes the prenylation of p-hydroxybenzoate with an all-trans polyprenyl group, an important step in ubiquinone (CoQ) biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260122 [Multi-domain]  Cd Length: 272  Bit Score: 317.10  E-value: 6.68e-108
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  69 MRVDKPIGTWLLYWPCTWSIAMATPAGQLPSIYMLSLFGAGAFLMRSAGCVINDLWDKDFDKKVERTKLRPLACGSLTEK 148
Cdd:cd13959   1 MRLDKPIGTLLLLPPALWGLLLAAGGLPLPLLKLLLLFLLGAFLMRSAGCTINDIADRDIDAKVPRTKNRPLASGAISVK 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247 149 QAIGLLAGLLSSSLAILLQLNWYSVAVGASSMALVVGYPLAKRFTYWPQFVLGATLNWSVLIAWAELGHFNDFGIfLPLY 228
Cdd:cd13959  81 EALLFLAVQLLLGLALLLQLNPLTILLSPIALLLVLIYPLMKRFTYWPQLVLGLAFGWGPLMGWAAVTGSLPLPA-LLLY 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247 229 TATILHTVIYDTIYSHQDKADDIMIGVKSTALRLGADTKKWLSAFGVGTVASLTACGIASDQTWPYYVALAAtTAQLGWQ 308
Cdd:cd13959 160 LAVIFWTAGYDTIYAHQDREDDRKIGVKSTAVLFGDRTKLILALLLHLFVALLLLAGGLAGLGWPYYLGLGA-AAHLLWQ 238

                       250       260       270
                ....*....|....*....|....*....|....
gi 32565247 309 VGTVDIDNG-SDCWDKFKSNSWMGIILFSGIVAS 341
Cdd:cd13959 239 EHRLDLPDPlRSCLAFFLSNGWVGLLLFAGLLLD 272
UbiA COG0382
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate ...
 63-340 2.08e-66

4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate polyprenyltransferase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440151  Cd Length: 280  Bit Score: 211.63  E-value: 2.08e-66
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  63 KPYLQLMRVDKPIGTWLLYWPCTWSIAMAtpAGQLPSIYMLSLFGAGAFLMRSAGCVINDLWDKDFDKKVERTKLRPLAC 142
Cdd:COG0382   1 RAYLRLLRLDRPIGILLLLWPTLWALFLA--AGGLPDLLLLLLAVLGTVLMRSAGYVINDYFDREIDRINERKPNRPLAS 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247 143 GSLTEKQAIGLLAGLLSSSLAILLQLNWYSVAVGASSMALVVGYPL-AKRFTYWPQFVLGATLNWSVLIAWAELGHFNDF 221
Cdd:COG0382  79 GRISLREALLLAIVLLLLALALALLLNPLTFLLALAALALAWAYSLfLKRFTLLGNLVLGLLFGLGILMGFAAVTGSLPL 158

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247 222 GIFLpLYTATILHTVIYDTIYSHQDKADDIMIGVKSTALRLGADTKKW-LSAFGVGTVASLTACGIASDQTWPYYVALAA 300
Cdd:COG0382 159 SAWL-LALAAFLWTLAYDTIYDLEDREGDRKIGIKTLAILFGVRDALIiAGVLYALAVLLLLLLGLLAGLGLLYLLGLLA 237

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....
gi 32565247 301 tTAQLGWQVGTVDID----NGSDCWDKFKSNSWMGIILFSGIVA 340
Cdd:COG0382 238 -ALLLLYLSQLWLLRprkkDPARALKLFKLNMLLGLLLFLGIAL 280
UbiA pfam01040
UbiA prenyltransferase family;
80-324 2.37e-44

UbiA prenyltransferase family;


Pssm-ID: 460038 [Multi-domain]  Cd Length: 250  Bit Score: 153.54  E-value: 2.37e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247    80 LYWPCTWSIAMAtpAGQLPSIYMLSLFGAGAFLMRSAGCVINDLWDKDFDKKVERTKLRPLACGSLTEKQAIGLLAGLLS 159
Cdd:pfam01040   1 LLIPALAGLALA--AGGVPDLLLLLLALLGTVLARAAANALNDYYDRDIDAIMPRTPNRPLPSGRISPREALIFALVLLA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247   160 SSLAILLQLNWYSVAVGASSMALVVGYPL-AKRFTYWPQFVLGATLNWSVLIAWAELGHFNDFGIFLpLYTATILHTVIY 238
Cdd:pfam01040  79 LGLLLLLLLNPLTALLGLAALLLYVLYTLrLKRRTLLGQLVGGLAFGLPPLLGWAAVTGSLSPLALL-LALALFLWTWAI 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247   239 DTIYSHQDKADDIMIGVKSTALRLGADTKKWLSA-FGVGTVASLTACGIASDQTWPYYVALAATTAQLGWQVGTVDIDNG 317
Cdd:pfam01040 158 ALANDLRDREDDRKAGIKTLPVVLGRKAARILLAlLLAVALLLLLLLLLLLLGGLYLLLALLLAALALLYAARLLRLRDP 237


                  ....*..
gi 32565247   318 SDCWDKF 324
Cdd:pfam01040 238 KKDAKAF 244
 
Name Accession Description Interval E-value
PLN02809 PLN02809
4-hydroxybenzoate nonaprenyltransferase
 59-343 3.33e-132

4-hydroxybenzoate nonaprenyltransferase


Pssm-ID: 178405  Cd Length: 289  Bit Score: 379.42  E-value: 3.33e-132
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247   59 PPNLKPYLQLMRVDKPIGTWLLYWPCTWSIAMATPAGQLPSIYMLSLFGAGAFLMRSAGCVINDLWDKDFDKKVERTKLR 138
Cdd:PLN02809   3 PPSLRPYAKLARLDKPIGTWLLAWPCMWSIALAAPPGSLPDLKMLALFGCGALLLRGAGCTINDLLDRDIDKKVERTKLR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  139 PLACGSLTEKQAIGLLAGLLSSSLAILLQLNWYSVAVGASSMALVVGYPLAKRFTYWPQFVLGATLNWSVLIAWAELGHF 218
Cdd:PLN02809  83 PIASGALTPFQGVGFLGAQLLLGLGILLQLNNYSRILGASSLLLVFTYPLMKRFTFWPQAFLGLTFNWGALLGWAAVKGS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  219 NDFGIFLPLYTATILHTVIYDTIYSHQDKADDIMIGVKSTALRLGADTKKWLSAFGVGTVASLTACGIASDQTWPYYVAL 298
Cdd:PLN02809 163 LDPAVVLPLYASGVCWTLVYDTIYAHQDKEDDLKVGVKSTALRFGDDTKLWLTGFGAASIGGLALSGYNAGLGWPYYAGL 242

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 32565247  299 AATTAQLGWQVGTVDIDNGSDCWDKFKSNSWMGIILFSGIVASTL 343
Cdd:PLN02809 243 AAAAGHLAWQIQTVDLSSRADCNRKFVSNKWFGAIVFAGIVLGKL 287
ubiA_proteo TIGR01474
4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of ...
 62-343 4.88e-112

4-hydroxybenzoate polyprenyl transferase, proteobacterial; This model represents a family of integral membrane proteins that condenses para-hydroxybenzoate with any of several polyprenyldiphosphates. Heterologous expression studies suggest that for, many but not all members, the activity seen (e.g. octaprenyltransferase in E. coli) reflects available host isoprenyl pools rather than enzyme specificity. A fairly deep split by both clustering (UPGMA) and phylogenetics (NJ tree) separates this group (mostly Proteobacterial and mitochondrial), with several characterized members, from another group (mostly archaeal and Gram-positive bacterial) lacking characterized members. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 130539  Cd Length: 281  Bit Score: 328.12  E-value: 4.88e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247    62 LKPYLQLMRVDKPIGTWLLYWPCTWSIAMATPAGQLPSIYMLSLFGAGAFLMRSAGCVINDLWDKDFDKKVERTKLRPLA 141
Cdd:TIGR01474   1 LLPYAKLMRADKPIGTLLLLWPCLWSLLLAAQAGGIPPLYLLGLFTVGAILMRGAGCVINDIWDRDFDPQVERTKSRPLA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247   142 CGSLTEKQAIGLLAGLLSSSLAILLQLNWYSVAVGASSMALVVGYPLAKRFTYWPQFVLGATLNWSVLIAW-AELGHFND 220
Cdd:TIGR01474  81 SGAVSVRQAILFLLVQLLVALGVLLQLNPLTILLGVASLALVATYPFMKRITYWPQLVLGLAFGWGALMGWaAVTGDLST 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247   221 FGIFlpLYTATILHTVIYDTIYSHQDKADDIMIGVKSTALRLGADTKKWLSAFGVGTVASLTACGIASDQTWPYYVALAA 300
Cdd:TIGR01474 161 AAWV--LYLANILWTLGYDTIYAMQDKEDDIKIGVKSTALRFGDNTKPWLGGLYALMILLLALAGLIAGLGPVYYLGLAA 238

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 32565247   301 TTAQLGWQVGTVDIDNGSDCWDKFKSNSWMGIILFSGIVASTL 343
Cdd:TIGR01474 239 AALLLIRQIATLDIRDPENCLKLFKANNYVGLLLFAGIALGWL 281
PT_UbiA_COQ2 cd13959
4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known ...
 69-341 6.68e-108

4-Hydroxybenzoate polyprenyltransferase; 4-Hydroxybenzoate polyprenyltransferase, also known as Coq2, catalyzes the prenylation of p-hydroxybenzoate with an all-trans polyprenyl group, an important step in ubiquinone (CoQ) biosynthesis. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260122 [Multi-domain]  Cd Length: 272  Bit Score: 317.10  E-value: 6.68e-108
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  69 MRVDKPIGTWLLYWPCTWSIAMATPAGQLPSIYMLSLFGAGAFLMRSAGCVINDLWDKDFDKKVERTKLRPLACGSLTEK 148
Cdd:cd13959   1 MRLDKPIGTLLLLPPALWGLLLAAGGLPLPLLKLLLLFLLGAFLMRSAGCTINDIADRDIDAKVPRTKNRPLASGAISVK 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247 149 QAIGLLAGLLSSSLAILLQLNWYSVAVGASSMALVVGYPLAKRFTYWPQFVLGATLNWSVLIAWAELGHFNDFGIfLPLY 228
Cdd:cd13959  81 EALLFLAVQLLLGLALLLQLNPLTILLSPIALLLVLIYPLMKRFTYWPQLVLGLAFGWGPLMGWAAVTGSLPLPA-LLLY 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247 229 TATILHTVIYDTIYSHQDKADDIMIGVKSTALRLGADTKKWLSAFGVGTVASLTACGIASDQTWPYYVALAAtTAQLGWQ 308
Cdd:cd13959 160 LAVIFWTAGYDTIYAHQDREDDRKIGVKSTAVLFGDRTKLILALLLHLFVALLLLAGGLAGLGWPYYLGLGA-AAHLLWQ 238

                       250       260       270
                ....*....|....*....|....*....|....
gi 32565247 309 VGTVDIDNG-SDCWDKFKSNSWMGIILFSGIVAS 341
Cdd:cd13959 239 EHRLDLPDPlRSCLAFFLSNGWVGLLLFAGLLLD 272
UbiA COG0382
4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate ...
 63-340 2.08e-66

4-hydroxybenzoate polyprenyltransferase [Coenzyme transport and metabolism]; 4-hydroxybenzoate polyprenyltransferase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440151  Cd Length: 280  Bit Score: 211.63  E-value: 2.08e-66
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  63 KPYLQLMRVDKPIGTWLLYWPCTWSIAMAtpAGQLPSIYMLSLFGAGAFLMRSAGCVINDLWDKDFDKKVERTKLRPLAC 142
Cdd:COG0382   1 RAYLRLLRLDRPIGILLLLWPTLWALFLA--AGGLPDLLLLLLAVLGTVLMRSAGYVINDYFDREIDRINERKPNRPLAS 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247 143 GSLTEKQAIGLLAGLLSSSLAILLQLNWYSVAVGASSMALVVGYPL-AKRFTYWPQFVLGATLNWSVLIAWAELGHFNDF 221
Cdd:COG0382  79 GRISLREALLLAIVLLLLALALALLLNPLTFLLALAALALAWAYSLfLKRFTLLGNLVLGLLFGLGILMGFAAVTGSLPL 158

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247 222 GIFLpLYTATILHTVIYDTIYSHQDKADDIMIGVKSTALRLGADTKKW-LSAFGVGTVASLTACGIASDQTWPYYVALAA 300
Cdd:COG0382 159 SAWL-LALAAFLWTLAYDTIYDLEDREGDRKIGIKTLAILFGVRDALIiAGVLYALAVLLLLLLGLLAGLGLLYLLGLLA 237

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....
gi 32565247 301 tTAQLGWQVGTVDID----NGSDCWDKFKSNSWMGIILFSGIVA 340
Cdd:COG0382 238 -ALLLLYLSQLWLLRprkkDPARALKLFKLNMLLGLLLFLGIAL 280
UbiA pfam01040
UbiA prenyltransferase family;
80-324 2.37e-44

UbiA prenyltransferase family;


Pssm-ID: 460038 [Multi-domain]  Cd Length: 250  Bit Score: 153.54  E-value: 2.37e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247    80 LYWPCTWSIAMAtpAGQLPSIYMLSLFGAGAFLMRSAGCVINDLWDKDFDKKVERTKLRPLACGSLTEKQAIGLLAGLLS 159
Cdd:pfam01040   1 LLIPALAGLALA--AGGVPDLLLLLLALLGTVLARAAANALNDYYDRDIDAIMPRTPNRPLPSGRISPREALIFALVLLA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247   160 SSLAILLQLNWYSVAVGASSMALVVGYPL-AKRFTYWPQFVLGATLNWSVLIAWAELGHFNDFGIFLpLYTATILHTVIY 238
Cdd:pfam01040  79 LGLLLLLLLNPLTALLGLAALLLYVLYTLrLKRRTLLGQLVGGLAFGLPPLLGWAAVTGSLSPLALL-LALALFLWTWAI 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247   239 DTIYSHQDKADDIMIGVKSTALRLGADTKKWLSA-FGVGTVASLTACGIASDQTWPYYVALAATTAQLGWQVGTVDIDNG 317
Cdd:pfam01040 158 ALANDLRDREDDRKAGIKTLPVVLGRKAARILLAlLLAVALLLLLLLLLLLLGGLYLLLALLLAALALLYAARLLRLRDP 237


                  ....*..
gi 32565247   318 SDCWDKF 324
Cdd:pfam01040 238 KKDAKAF 244
ubiA PRK12873
4-hydroxybenzoate polyprenyltransferase;
57-344 1.70e-39

4-hydroxybenzoate polyprenyltransferase;


Pssm-ID: 171787 [Multi-domain]  Cd Length: 294  Bit Score: 142.11  E-value: 1.70e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247   57 SSPPNLKPYLQLMRVDKPIGTWLLYWPCTWSIAMaTPAGQlPSIYMLSLFGAGAFLMRSAGCVINDLWDKDFDKKVERTK 136
Cdd:PRK12873   2 SRSIKLSPWFELLRWNKPTGRLILLIPAGWSLWL-TPSAP-PSLLLLLLIILGGLAVSGAGCIANDLWDRRIDRKVERTK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  137 LRPLACGSLTEKQA----IGLLAGLLSSSLAILLQLNWYSVAVGASSMALVVGYPLAKRFTYWPQFVLGATLNWSVLIAW 212
Cdd:PRK12873  80 NRPLARGKISLKTAysllIVLLLLSLFVVLSLPQPSRNLCLSLAFLALPPILIYPSAKRWFAYPQAILALCWGFAVLIPW 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  213 -AELGHFNDFGIFLPLYTATILHTVIYDTIYSHQDKADDIMIGVKSTALRLGADTKKWLSAFGVGTVASLTACGIASDQT 291
Cdd:PRK12873 160 aAAEGSLNGGWPLLFCWLATLLWTFGFDTVYAMADRRDDAKIGLNSSALSLGSNALKTVQICYFLTSIFLALAAFIAQVG 239

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 32565247  292 WPYYvaLAATTAQLGWQVGTVDID----NGSDCWDKFKSNSWMGIILFSGIVASTLL 344
Cdd:PRK12873 240 FIFW--PFWLIASIGMQRDILKLFpekqSIKTIGNHFSNQVILGSLLLLGLILARGG 294
PT_UbiA cd13956
UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA ...
 66-309 1.10e-17

UbiA family of prenyltransferases (PTases); Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260119 [Multi-domain]  Cd Length: 271  Bit Score: 82.01  E-value: 1.10e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  66 LQLMRvdkPIGTWLLYWPCTWSIAMATPAGQLPSIYMLSLFGAgAFLMRSAGCVINDLWDKDFDKkvERTKLRPLACGSL 145
Cdd:cd13956   1 LRLMR---PYTLLYVLAPALAGAALAGAFAGPLPALLLLALLA-VFLGAGAGYALNDYTDRELDA--INKPDRPLPSGRL 74

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247 146 TEKQAIGLLAGLLSSSLAILLQLNWYSVAVGASSMALVVGYPLAKRFTYWPQ-FVLGATLNWSVLIAW--AELGHFNDF- 221
Cdd:cd13956  75 SPRQALAFAAALLLVGLALALALGPLALLLLLAGLLLGLAYSLGLKRLKLGGwGVLGYATGLALLPGLgaVAAGGLVPLa 154

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247 222 GIFLPLYTATILHTVIYDTIyshQDKADDIMIGVKSTALRLGADTKKWLSAFGVgtVASLTACGIASDQTWPYYVALAAT 301
Cdd:cd13956 155 LLLALVFLLLGLGINLYNDL---PDVEGDRAAGIRTLPVRLGPRRARRLAAGLL--LAALILVVLLAVAGLLGPLALLAL 229


                ....*...
gi 32565247 302 TAQLGWQV 309
Cdd:cd13956 230 LAVALLAL 237
ubiA PRK12888
4-hydroxybenzoate octaprenyltransferase;
103-335 1.50e-14

4-hydroxybenzoate octaprenyltransferase;


Pssm-ID: 183814  Cd Length: 284  Bit Score: 73.22  E-value: 1.50e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  103 LSLFGAGAFLMrsagcVINDLWDKDFDKKVERTKLRPLACGSLTEKQAIGLLAGLLSSSLAILLQLNWYSVAVGASSMAL 182
Cdd:PRK12888  46 VAMVGARTFAM-----AANRIIDREIDARNPRTAGRELVTGAVSVRTAWTGALVALAVFLGAAALLNPLCLALAPLAVAP 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  183 VVGYPLAKRFTYWPQFVLGATLNWSVLIAW-AELGHFNDFGIFLPLytATILHTVIYDTIYSHQDKADDIMIGVKSTALR 261
Cdd:PRK12888 121 LVVYPYAKRFTNFPHAILGLAQAVGPVGAWiAVTGTWSWPAVLLGL--AVGLWIGGFDLIYACQDAEVDRRIGVRSVPAR 198

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 32565247  262 LGADTKKWLS-AFGVGTVASLTACGIASDQTWPYYVALAATTAQLGWQVGTVDIDNGSDCWDKFKS-NSWMGIILF 335
Cdd:PRK12888 199 FGVRAALWASrVAHVVTFALFVWFGLAVGFGALWWIGLAITAGAFAYEHAIVSPTDLSRVNRAFFTaNGFVGIALF 274
ubiA PRK13106
prenyltransferase; Reviewed
 94-344 1.34e-13

prenyltransferase; Reviewed


Pssm-ID: 237283  Cd Length: 300  Bit Score: 70.53  E-value: 1.34e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247   94 AGQLPSIYMLSLFGAGAFLMRSAGCVINDLWDKDFDKKVERTKLRPLACGSLTEKQAIGLLAGLLSSSLAILLQLNWYSV 173
Cdd:PRK13106  42 IKGIPPISTLILIFLALFFLRTAGMTNDNLADLEIDAKNPRTKNRPLVTGAIKISEAKALITAGLILFFASAYLVNRWAL 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  174 AVGASSMALVVGYPLAKRFTYWPQFVLGATLNWSVLI-AWAELG-HFNDFGIFLP-----LYTATILHTVIYDTIYSHQD 246
Cdd:PRK13106 122 LLSPIVALIAMSYPYMKRYTAFANYHLASIQGLAVFSgAVAVLGlYANSLIQVLLrvpwlFVIGTILWAAGFDLYNHIPD 201

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  247 KADDIMIGVKSTALRLGADTKKWLSAFGVGTVASLTACGIASDQTWPYYVALAATTAQLGWQVGTVDIDNgsDCWDKFKS 326
Cdd:PRK13106 202 AEFDREMGLHSFAVVLGKWALTFAGLNQLFSVVLDLLGDLYYGLGPIAIAATILHGLIMAYAYYLASKKG--DFGRAFYY 279

                        250
                 ....*....|....*...
gi 32565247  327 NSWMGIILFSGIVASTLL 344
Cdd:PRK13106 280 NIYSSIVLGLGIIIDVLL 297
ubiA PRK12886
prenyltransferase; Reviewed
 94-344 1.65e-09

prenyltransferase; Reviewed


Pssm-ID: 237247  Cd Length: 291  Bit Score: 58.16  E-value: 1.65e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247   94 AGQLPSIY-----MLSLFGAgaflmRSAGCVINDLWDKDFDKKVERTKLRPLACGSLTEKQAIGLLAGLLSSSLAILLQL 168
Cdd:PRK12886  35 ALGLPGASqldwiLMAMVGA-----RTAAMGFNRLIDAEIDARNPRTAGRAIPAGLISKGSAILFIVLSSLLMLFAAWFL 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  169 NWYSVAVGASSMALVVGYPLAKRFTYWPQFVLGATLNWSVLIAW-AELGHFNDFGIFLPLytATILHTVIYDTIYSHQDK 247
Cdd:PRK12886 110 NPLCLYLSPPALFFLLLYSYCKRFTALAHVVLGFCLALAPLGAWiAIRGTIELPAILLGL--AVLFWVAGFDILYALQDL 187

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  248 ADDIMIGVKSTALRLGADTKKWLS-AFGVGTVASLTACGIASDQTWPYYVALAATTAQLGWQVGTVDIDNGSDCWDKF-K 325
Cdd:PRK12886 188 EFDRKEGLHSIPAKLGVNGSLWIArVFHLLMIGFLFALGISAGLGPWFLAGLAVTGILLLYEHWLLRGGDLTRLDAAFfN 267

                        250
                 ....*....|....*....
gi 32565247  326 SNSWMGIILFSGIVASTLL 344
Cdd:PRK12886 268 MNGYISVTLFAATLFDRLF 286
CyoE COG0109
Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport ...
 45-151 1.19e-07

Polyprenyltransferase (heme O synthase) [Coenzyme transport and metabolism, Lipid transport and metabolism];


Pssm-ID: 439879  Cd Length: 299  Bit Score: 52.44  E-value: 1.19e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  45 MSLIPTASSlvASSPPNLKPYLQLMrvdKPIGTWLLYWpcTWSIAMATPAGQLPSIYMLSLFGAGAFLMRSAGCVINDLW 124
Cdd:COG0109   1 MSSASASSA--ASLRSTLRDYLALT---KPRIILLLLF--TALAGMLLAAGGLPDLLLLLLTLLGGALAAGAANALNNYI 73

                        90       100
                ....*....|....*....|....*..
gi 32565247 125 DKDFDKKVERTKLRPLACGSLTEKQAI 151
Cdd:COG0109  74 DRDIDALMKRTKNRPLPTGRISPREAL 100
PRK04375 PRK04375
protoheme IX farnesyltransferase; Provisional
 53-151 3.99e-06

protoheme IX farnesyltransferase; Provisional


Pssm-ID: 235293  Cd Length: 296  Bit Score: 47.83  E-value: 3.99e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247   53 SLVASSPPNLKPYLQLMrvdKPIGTWLLYWPCTWSIAMATPAGQLPSIYMLSLFGAGafLMRSAGCVINDLWDKDFDKKV 132
Cdd:PRK04375   1 VSSSSSRATLKDYLALT---KPRVISLNLFTALGGMLLAPPGVPPLLLLLLTLLGIA--LVAGAAGALNNYIDRDIDAKM 75

                         90
                 ....*....|....*....
gi 32565247  133 ERTKLRPLACGSLTEKQAI 151
Cdd:PRK04375  76 ERTKNRPLVTGRISPREAL 94
PT_UbiA_Cox10 cd13957
Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O ...
 66-195 8.45e-06

Protoheme IX farnesyltransferase; Protoheme IX farnesyltransferase (also called heme O synthase, heme A:farnesyltransferase, cytochrome c oxidase subunit X [Cox10]) converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of the heme B porphyrin ring with a hydroxyethyl farnesyl side group. It is localized at the mitochondrial inner membrane. Eukaryotic Cox10 is important for the maturation of the heme A prosthetic group of cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, that catalyzes the electron transfer from reduced cytochrome c to oxygen. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260120  Cd Length: 271  Bit Score: 46.66  E-value: 8.45e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  66 LQLMrvdKPIGTWLLYWPCTWSIAMATPAGQLPSIYMLSLFGAgaFLMRSAGCVINDLWDKDFDKKVERTKLRPLACGSL 145
Cdd:cd13957   1 LELT---KPRITLLVLLTALAGYLLAPGGVPDLLLLLLTLLGT--ALVSASANALNQYIERDIDAKMKRTRNRPLPSGRI 75

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|...
gi 32565247 146 TEKQAIGLLAGLLSS-SLAILLQLNWYSVAVGASSMAL-VVGY-PLAKRFTYW 195
Cdd:cd13957  76 SPKHALIFGLVLGILgLALLALFVNPLTALLGLLGIFLyVFVYtPLKKRTTPL 128
ubiA PRK12876
prenyltransferase; Reviewed
 104-201 2.08e-05

prenyltransferase; Reviewed


Pssm-ID: 237244  Cd Length: 300  Bit Score: 45.89  E-value: 2.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  104 SLFGAGAFLM-RSAGCVINDLWDKDFDKKVERTKLRPLACGSLTEKQAIGLLAGLLSSSLAILLQLNWYSVAVGASSMAL 182
Cdd:PRK12876  49 ISLGGSAFFCaRTVGIIVNQIIDCAIDKKNPRTSSRVLPAKLLSINFSMLLLTLCSFLFLSLCWLLNPLCFSLAVLSTLL 128

                         90
                 ....*....|....*....
gi 32565247  183 VVGYPLAKRFTYWPQFVLG 201
Cdd:PRK12876 129 MIIYPYTKRVTFLCHWILG 147
PT_UbiA_2 cd13963
UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of ...
 94-151 7.22e-05

UbiA family of prenyltransferases (PTases), Unknown subgroup; Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways. The function of this subgroup is unknown.


Pssm-ID: 260126  Cd Length: 278  Bit Score: 44.00  E-value: 7.22e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 32565247  94 AGQLPSIYML--SLFGAGAF-LMRSAGCVINDLWDKDFDKKVERTKLRPLACGSLTEKQAI 151
Cdd:cd13963  23 AGQLFDPDLLlaALLAFVAFcLAASAVYILNDLLDLEADRLHPTKRNRPIASGRLSIPAAL 83
PT_UbiA_UBIAD1 cd13962
1,4-Dihydroxy-2-naphthoate octaprenyltransferase; Human UBIAD1 is an enzyme involved in the ...
 88-300 1.49e-03

1,4-Dihydroxy-2-naphthoate octaprenyltransferase; Human UBIAD1 is an enzyme involved in the synthesis of MK-4. Menaquinones (MKs, also called bacterial forms) are one of the two forms of natural vitamin K, the other being the plant form, phylloquinone (PK). All forms of vitamin K have a 2-methyl-1,4-naphthoquinone (menadione; K3) ring structure in common. At the 3-position of the ring, PK has a phytyl side chain while MKs have several repeating prenyl units. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways.


Pssm-ID: 260125  Cd Length: 283  Bit Score: 39.80  E-value: 1.49e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  88 IAMATPAGQLPSIYMLSLFGAGAFLMRSAGCVINDLWD--KDFDKKVERTKLRPLACGSLTEKQ----AIGLLAGLLSSS 161
Cdd:cd13962  20 TALAYYLGGFFNWLLFLLALLAALLLQIGVNLANDYFDykKGTDTEPRSGPSRVLVSGLLSPRQvlraALVLLLLAALLG 99

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247 162 LAILLQLNWYSVAVGASSMALVVGY-----PLAKR--------FTYWP------QFVLGATLNWSVLIAWAELGhfndfg 222
Cdd:cd13962 100 LYLVALGGWLLLLLGLLGILAGYFYtggpfPLSYRglgelfvfLFFGLlavlgtYYVQTGSLSWEVLLAALPLG------ 173

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 32565247 223 iflpLYTATILHTViydtiySHQDKADDIMIGVKSTALRLGAD-TKKWLSAFGVGTVASLTACGIASDQTWPYYVALAA 300
Cdd:cd13962 174 ----LLIAAILLAN------NIRDIEADRAAGKRTLAVRLGRKrARRLYAALLLLAYLLLLLLVLLGLLPLWSLLALLS 242
ubiA PRK12874
4-hydroxybenzoate polyprenyltransferase;
120-273 2.16e-03

4-hydroxybenzoate polyprenyltransferase;


Pssm-ID: 237242  Cd Length: 291  Bit Score: 39.60  E-value: 2.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247  120 INDLWDKDFDKKVERTKLRPLACGSLTEKQAIGLLAGLLSSSLAILLQLNWYSVAVGASSMALVVGYPLAKRFTYWPQFV 199
Cdd:PRK12874  66 FNRLVDRDIDKDNPRTANRPSVDGRISVKSMVLFIVLNALIFIGVSYFINPLAFKLSFPFLIVLGGYSYFKRFSSLAHLV 145

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 32565247  200 LGATLNWSVLI-AWAELGHFNDFGIFLPLytATILHTVIYDTIYSHQDKADDIMIGVKSTALRLGADTKKWLSAF 273
Cdd:PRK12874 146 LGLSLGLAPIAgVVAVLGEIPLWSVFLAL--GVMFWVAGFDLLYSLQDMEFDKKRGLHSIPSKFGEKATLFISRL 218
PRK08238 PRK08238
UbiA family prenyltransferase;
38-145 5.23e-03

UbiA family prenyltransferase;


Pssm-ID: 236195 [Multi-domain]  Cd Length: 479  Bit Score: 38.70  E-value: 5.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247   38 STSTKQPMSLIPTASSLVASSPPNLKPYLQLMRVDKpigtW----LLYWPctwsiamATPAGQLPSIYML--SLFGAGAF 111
Cdd:PRK08238 167 SPGVARAARALGPVERVFPPRPARLRTWLKALRVHQ----WaknlLVFVP-------LLAAHQFGDLQALlaALLAFLAF 235

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 32565247  112 -LMRSAGCVINDLWDKDFDKKVERTKLRPLACGSL 145
Cdd:PRK08238 236 sLCASAVYILNDLLDLEADRAHPRKRRRPFASGAL 270
PRK12324 PRK12324
decaprenyl-phosphate phosphoribosyltransferase;
62-151 5.49e-03

decaprenyl-phosphate phosphoribosyltransferase;


Pssm-ID: 237058  Cd Length: 295  Bit Score: 38.30  E-value: 5.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 32565247   62 LKPYLQLMRvdkpigtwllywPCTWS---IAMATP--AGQLPSIYML--SLFGAGAF-LMRSAGCVINDLWDKDFDKKVE 133
Cdd:PRK12324  11 LAGYLKLLR------------PKQWIknlFVFAAPifAGNLLNPGALlkVLLAFVLFcLASSAVYLVNDIRDVEADRLHP 78

                         90
                 ....*....|....*...
gi 32565247  134 RTKLRPLACGSLTEKQAI 151
Cdd:PRK12324  79 TKRNRPIASGVVSVSLAY 96
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH