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Conserved domains on  [gi|30692908|ref|NP_851096|]
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high chlorophyll fluorescent 109 [Arabidopsis thaliana]

Protein Classification

PCRF domain-containing protein( domain architecture ID 1750053)

peptide chain release factor (PCRF) domain-containing protein similar to Homo sapiens mitochondrial peptide chain release factor 1 (MTRF1), MTRF1-like and 28S mitochondrial ribosomal protein S35 (MRPS35)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PCRF super family cl40670
This domain is found in peptide chain release factors;
80-445 1.59e-137

This domain is found in peptide chain release factors;


The actual alignment was detected with superfamily member TIGR00020:

Pssm-ID: 477417 [Multi-domain]  Cd Length: 364  Bit Score: 399.53  E-value: 1.59e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908    80 DFYTLRKDVEIASARVEEIRASANLQQLEQEITNLESKATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAET 159
Cdd:TIGR00020   1 EINEVNNRIEDLTSRLDTVRGSLDPEKKKARLEELEKEMEDPNFWNDQERAQAVIKERSSLEAVLDTLEELKNSLEDLSE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908   160 IVKLTEEMDSTDVSLLEEAMgiIKELNKSLDKFELTQLLSGPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQR 239
Cdd:TIGR00020  81 LLELAVEEDDEETFNELDAE--LKALEKKLAELELRTMLSGEYDANNAYLTIQAGAGGTEAQDWASMLYRMYLRWAERRG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908   240 YKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGVEVMPLLPEEaVGIEIPEEDL 319
Cdd:TIGR00020 159 FKVEIIDYSEGEEAGIKSVTILIKGPYAYGYLKSEQGVHRLVRISPFDANGRRHTSFASVFVMPEVDDD-IDIEIKPEDL 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908   320 DISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRCTEERSQLANKTRALIRLKAKLMVIAEEQRATEIKEIRGDAVKAEW 399
Cdd:TIGR00020 238 RIDTYRASGAGGQHVNKTDSAVRITHIPTGIVVQCQNDRSQHKNKDSAMKVLKAKLYELEMEKEQAEKDAKEGEKSEIGW 317

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 30692908   400 GQQIRNYVFHPYKLVKDVRTGHETSDITSVMDGDLDPFIKAYLKHK 445
Cdd:TIGR00020 318 GSQIRSYVLHPYSMVKDLRTGYETGNVQAVLDGDIDQFIEAYLKWK 363
 
Name Accession Description Interval E-value
prfB TIGR00020
peptide chain release factor 2; In many but not all taxa, there is a conserved real ...
 80-445 1.59e-137

peptide chain release factor 2; In many but not all taxa, there is a conserved real translational frameshift at a TGA codon. RF-2 helps terminate translation at TGA codons and can therefore regulate its own production by readthrough when RF-2 is insufficient. There is a Pfam model called "RF-1" for the superfamily of RF-1, RF-2, mitochondrial, RF-H, etc. [Protein synthesis, Translation factors]


Pssm-ID: 272858 [Multi-domain]  Cd Length: 364  Bit Score: 399.53  E-value: 1.59e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908    80 DFYTLRKDVEIASARVEEIRASANLQQLEQEITNLESKATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAET 159
Cdd:TIGR00020   1 EINEVNNRIEDLTSRLDTVRGSLDPEKKKARLEELEKEMEDPNFWNDQERAQAVIKERSSLEAVLDTLEELKNSLEDLSE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908   160 IVKLTEEMDSTDVSLLEEAMgiIKELNKSLDKFELTQLLSGPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQR 239
Cdd:TIGR00020  81 LLELAVEEDDEETFNELDAE--LKALEKKLAELELRTMLSGEYDANNAYLTIQAGAGGTEAQDWASMLYRMYLRWAERRG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908   240 YKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGVEVMPLLPEEaVGIEIPEEDL 319
Cdd:TIGR00020 159 FKVEIIDYSEGEEAGIKSVTILIKGPYAYGYLKSEQGVHRLVRISPFDANGRRHTSFASVFVMPEVDDD-IDIEIKPEDL 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908   320 DISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRCTEERSQLANKTRALIRLKAKLMVIAEEQRATEIKEIRGDAVKAEW 399
Cdd:TIGR00020 238 RIDTYRASGAGGQHVNKTDSAVRITHIPTGIVVQCQNDRSQHKNKDSAMKVLKAKLYELEMEKEQAEKDAKEGEKSEIGW 317

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 30692908   400 GQQIRNYVFHPYKLVKDVRTGHETSDITSVMDGDLDPFIKAYLKHK 445
Cdd:TIGR00020 318 GSQIRSYVLHPYSMVKDLRTGYETGNVQAVLDGDIDQFIEAYLKWK 363
PRK05589 PRK05589
peptide chain release factor 2; Provisional
 123-443 9.80e-123

peptide chain release factor 2; Provisional


Pssm-ID: 235520 [Multi-domain]  Cd Length: 325  Bit Score: 360.27  E-value: 9.80e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  123 FWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAETIVKLTEEMDStdvSLLEEAMGIIKELNKSLDKFELTQLLSGPY 202
Cdd:PRK05589   6 FWNDIKEAQEITSEEKYLKDKLDKYNHLRNRIEDIEVLCEMMSEEDD---EMKKEIISEVKNIKEEIDRFKIETLLSGEY 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  203 DKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGEKGTHRIVR 282
Cdd:PRK05589  83 DRNNAILTLHSGVGGTDAQDWTEMLLRMYTRWAEKKGYKVEIIDLLEGDEAGIKSVTLKITGEFAYGYLKAEKGIHRLVR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  283 QSPFNSKGLRQTSFSGVEVMPLLPEEAvGIEIPEEDLDISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRCTEERSQLA 362
Cdd:PRK05589 163 ISPFNANGKRQTSFASVEVLPELTDDQ-DIEIRSEDLKIDTYRAGGAGGQHVNKTESAVRITHIPTGIVVQCQNERSQHS 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  363 NKTRALIRLKAKLMVIAEEQRATEIKEIRGDAVKAEWGQQIRNYVFHPYKLVKDVRTGHETSDITSVMDGDLDPFIKAYL 442
Cdd:PRK05589 242 NKETAMKMLKSKLVELKERAHKEKIEDLTGELKDMGWGSQIRSYVFHPYNLVKDHRTGVETSNVDSVMDGDIDNFITQYL 321


                 .
gi 30692908  443 K 443
Cdd:PRK05589 322 K 322
PCRF pfam03462
PCRF domain; This domain is found in peptide chain release factors.
 107-299 1.18e-62

PCRF domain; This domain is found in peptide chain release factors.


Pssm-ID: 460929 [Multi-domain]  Cd Length: 192  Bit Score: 201.46  E-value: 1.18e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908   107 LEQEITNLESKATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAETIVKLTEEMDstdvsLLEEAMGIIKELN 186
Cdd:pfam03462   1 LEERYEELEALLSDPDVWDDQKRAQKLSKEYSELEPIVEAYREYKQALEDLEEAKELLEDPE-----LAELAEEELEELE 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908   187 KSLDKF--ELTQLLS--GPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKSATLEI 262
Cdd:pfam03462  76 KRLEELeeELKLLLLpkDPNDDKNAILEIRAGAGGDEAALFAGDLFRMYTRYAERKGWKVEVLDYSETEAGGIKEATFEI 155

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 30692908   263 EGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGV 299
Cdd:pfam03462 156 SGEGAYGRLKFESGVHRVQRVPPTESQGRIHTSFATV 192
PrfA COG0216
Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein ...
 104-440 1.39e-60

Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein chain release factor RF1 is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 439986 [Multi-domain]  Cd Length: 356  Bit Score: 201.38  E-value: 1.39e-60
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908 104 LQQLEQEITNLESKATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAETivklTEEM--DSTDVSLLEEAMGI 181
Cdd:COG0216   6 LEALEERYEELEALLSDPEVISDQKRFRKLSKEYAELEPIVEAYREYKKLLEDIEE----AKELleEESDPEMREMAKEE 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908 182 IKELNKSLDKFE--LTQLL--SGPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKS 257
Cdd:COG0216  82 LEELEARLEELEeeLKILLlpKDPNDDKNVILEIRAGTGGDEAALFAGDLFRMYSRYAERKGWKVEILSASEGELGGYKE 161

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908 258 ATLEIEGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGVEVMPllpE-EAVGIEIPEEDLDISFTRAGGKGGQNVNK 336
Cdd:COG0216 162 VIFRISGEGVYSRLKFESGVHRVQRVPETESQGRIHTSAATVAVLP---EaEEVDVEINPKDLRIDTFRSSGAGGQHVNT 238

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908 337 VETAVRITHIPTGVAVRCTEERSQLANKTRALIRLKAKLMVIAEEQRATEIKEIRGDAVkaewG-----QQIRNYVFhPY 411
Cdd:COG0216 239 TDSAVRITHLPTGIVVECQDERSQHKNKAKAMKVLRARLYEAEQQKQQAEIAAERKSQV----GsgdrsERIRTYNF-PQ 313

                       330       340
                ....*....|....*....|....*....
gi 30692908 412 KLVKDVRTGHETSDITSVMDGDLDPFIKA 440
Cdd:COG0216 314 GRVTDHRINLTLYKLDEVMEGDLDELIDA 342
PCRF smart00937
This domain is found in peptide chain release factors;
162-274 1.82e-38

This domain is found in peptide chain release factors;


Pssm-ID: 214923 [Multi-domain]  Cd Length: 116  Bit Score: 135.28  E-value: 1.82e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908    162 KLTEEMDstDVSLLEEAMGIIKELN----KSLDKFELTQLLSG-PYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGE 236
Cdd:smart00937   1 ELLEEEE--DDEMRELAEEELEELEaeleEELEELLKLLLLPKdPNDDKNAILEIRAGAGGDEAALFAGDLLRMYLRYAE 78

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 30692908    237 KQRYKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGE 274
Cdd:smart00937  79 RKGWKVEVLDESEGELGGIKEATLKISGEGAYGKLKFE 116
 
Name Accession Description Interval E-value
prfB TIGR00020
peptide chain release factor 2; In many but not all taxa, there is a conserved real ...
 80-445 1.59e-137

peptide chain release factor 2; In many but not all taxa, there is a conserved real translational frameshift at a TGA codon. RF-2 helps terminate translation at TGA codons and can therefore regulate its own production by readthrough when RF-2 is insufficient. There is a Pfam model called "RF-1" for the superfamily of RF-1, RF-2, mitochondrial, RF-H, etc. [Protein synthesis, Translation factors]


Pssm-ID: 272858 [Multi-domain]  Cd Length: 364  Bit Score: 399.53  E-value: 1.59e-137
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908    80 DFYTLRKDVEIASARVEEIRASANLQQLEQEITNLESKATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAET 159
Cdd:TIGR00020   1 EINEVNNRIEDLTSRLDTVRGSLDPEKKKARLEELEKEMEDPNFWNDQERAQAVIKERSSLEAVLDTLEELKNSLEDLSE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908   160 IVKLTEEMDSTDVSLLEEAMgiIKELNKSLDKFELTQLLSGPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQR 239
Cdd:TIGR00020  81 LLELAVEEDDEETFNELDAE--LKALEKKLAELELRTMLSGEYDANNAYLTIQAGAGGTEAQDWASMLYRMYLRWAERRG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908   240 YKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGVEVMPLLPEEaVGIEIPEEDL 319
Cdd:TIGR00020 159 FKVEIIDYSEGEEAGIKSVTILIKGPYAYGYLKSEQGVHRLVRISPFDANGRRHTSFASVFVMPEVDDD-IDIEIKPEDL 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908   320 DISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRCTEERSQLANKTRALIRLKAKLMVIAEEQRATEIKEIRGDAVKAEW 399
Cdd:TIGR00020 238 RIDTYRASGAGGQHVNKTDSAVRITHIPTGIVVQCQNDRSQHKNKDSAMKVLKAKLYELEMEKEQAEKDAKEGEKSEIGW 317

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 30692908   400 GQQIRNYVFHPYKLVKDVRTGHETSDITSVMDGDLDPFIKAYLKHK 445
Cdd:TIGR00020 318 GSQIRSYVLHPYSMVKDLRTGYETGNVQAVLDGDIDQFIEAYLKWK 363
PRK05589 PRK05589
peptide chain release factor 2; Provisional
 123-443 9.80e-123

peptide chain release factor 2; Provisional


Pssm-ID: 235520 [Multi-domain]  Cd Length: 325  Bit Score: 360.27  E-value: 9.80e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  123 FWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAETIVKLTEEMDStdvSLLEEAMGIIKELNKSLDKFELTQLLSGPY 202
Cdd:PRK05589   6 FWNDIKEAQEITSEEKYLKDKLDKYNHLRNRIEDIEVLCEMMSEEDD---EMKKEIISEVKNIKEEIDRFKIETLLSGEY 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  203 DKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGEKGTHRIVR 282
Cdd:PRK05589  83 DRNNAILTLHSGVGGTDAQDWTEMLLRMYTRWAEKKGYKVEIIDLLEGDEAGIKSVTLKITGEFAYGYLKAEKGIHRLVR 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  283 QSPFNSKGLRQTSFSGVEVMPLLPEEAvGIEIPEEDLDISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRCTEERSQLA 362
Cdd:PRK05589 163 ISPFNANGKRQTSFASVEVLPELTDDQ-DIEIRSEDLKIDTYRAGGAGGQHVNKTESAVRITHIPTGIVVQCQNERSQHS 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  363 NKTRALIRLKAKLMVIAEEQRATEIKEIRGDAVKAEWGQQIRNYVFHPYKLVKDVRTGHETSDITSVMDGDLDPFIKAYL 442
Cdd:PRK05589 242 NKETAMKMLKSKLVELKERAHKEKIEDLTGELKDMGWGSQIRSYVFHPYNLVKDHRTGVETSNVDSVMDGDIDNFITQYL 321


                 .
gi 30692908  443 K 443
Cdd:PRK05589 322 K 322
PRK07342 PRK07342
peptide chain release factor 2; Provisional
 117-445 5.43e-102

peptide chain release factor 2; Provisional


Pssm-ID: 235997 [Multi-domain]  Cd Length: 339  Bit Score: 307.96  E-value: 5.43e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  117 KATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAETIVKLTEEmdSTDVSLLEEAMGIIKELNKSLDKFELTQ 196
Cdd:PRK07342   2 KAEDPSLWNDAQEAQKLMRERQQLDDSINGINHLEQTLNDNIELIAMGEE--EGDKSIVEDAEKTIRDLKDEIDRRQIDA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  197 LLSGPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGEKG 276
Cdd:PRK07342  80 LLSGEADANDTYLEVHAGAGGTESQDWASMLLRMYTRWAERQGRKVEVLEVHDGEEAGIKSATILVKGHNAYGWLKTESG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  277 THRIVRQSPFNSKGLRQTSFSGVEVMPLLpEEAVGIEIPEEDLDISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRCTE 356
Cdd:PRK07342 160 VHRLVRISPYDSNARRHTSFASIWVYPVI-DDNIEVDVNESDVRIDTYRSSGAGGQHVNTTDSAVRITHIPTGIVVQCQQ 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  357 ERSQLANKTRALIRLKAKLMVIAEEQRATEIKEIRGDAVKAEWGQQIRNYVFHPYKLVKDVRTGHETSDITSVMDGDLDP 436
Cdd:PRK07342 239 ERSQHKNRAKAWSMLRARLYEEELKKREEATNAAAASKTDIGWGHQIRSYVLQPYQLVKDLRTGVESTNPQDVLDGDLNE 318


                 ....*....
gi 30692908  437 FIKAYLKHK 445
Cdd:PRK07342 319 FMEAALAHR 327
PRK06746 PRK06746
peptide chain release factor 2; Provisional
 123-445 2.81e-98

peptide chain release factor 2; Provisional


Pssm-ID: 75726 [Multi-domain]  Cd Length: 326  Bit Score: 297.80  E-value: 2.81e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  123 FWDDRTKAQETLSSLNDLKDrmrLLSEFKTMVEDAETIvKLTEEM--DSTDVSLLEEAMGIIKELNKSLDKFELTQLLSG 200
Cdd:PRK06746   6 FWDDQQGAQAVINEANALKD---MVGKFRQLDETFENL-EITHELlkEEYDEDLHEELESEVKGLIQEMNEYELQLLLSD 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  201 PYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGEKGTHRI 280
Cdd:PRK06746  82 PYDKNNAILELHPGAGGTESQDWGSMLLRMYTRWAEKRGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  281 VRQSPFNSKGLRQTSFSGVEVMPLLPEEaVGIEIPEEDLDISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRCTEERSQ 360
Cdd:PRK06746 162 VRISPFDSSGRRHTSFVSCEVVPEFNDE-VEIEVRTEDLKIDTYRASGAGGQHVNTTDSAVRITHTPTNTVVTCQSERSQ 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  361 LANKTRALIRLKAKLMVIAEEQRATEIKEIRGDAVKAEWGQQIRNYVFHPYKLVKDVRTGHETSDITSVMDGDLDPFIKA 440
Cdd:PRK06746 241 IKNREHAMKMLKAKLYQKKLEEQQAELDEIRGEQKEIGWGSQIRSYVFHPYSLVKDHRTNTEVGNVQAVMDGEIDPFIDA 320


                 ....*
gi 30692908  441 YLKHK 445
Cdd:PRK06746 321 YLRSR 325
PRK08787 PRK08787
peptide chain release factor 2; Provisional
 151-443 2.13e-90

peptide chain release factor 2; Provisional


Pssm-ID: 136970 [Multi-domain]  Cd Length: 313  Bit Score: 277.31  E-value: 2.13e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  151 KTMVEDAETIVKLTEEMDSTDVSLLEE----AMGIIKELNK---SLDKFELTQLLSGPYDKEGAVVYITAGAGGTDAQDW 223
Cdd:PRK08787   4 KTVIGIADVLSGLADAGELLDLAESEQdedtALAVIADLDKyqaHVEKLEFQRMFSGQMDGANAFVDIQAGAGGTEAQDW 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  224 ADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGVEVMP 303
Cdd:PRK08787  84 AEILLRMYLRWAESRGWKTELMEVSGGEVAGIKSATVRIEGEYAYGWLKTEIGVHRLVRKSPFDSDNRRHTSFTSVFVSP 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  304 LLpEEAVGIEIPEEDLDISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRCTEERSQLANKTRALIRLKAKLMVIAEEQR 383
Cdd:PRK08787 164 EV-DDNIEIDINPADLRTDVYRSSGAGGQHVNKTESAVRITHIPTNTVVACQTGRSQHQNRDNAMKMLAAKLYELEVQKR 242

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  384 ATEIKEIRGDAVKAEWGQQIRNYVFHPYKlVKDVRTGHETSDITSVMDGDLDPFIKAYLK 443
Cdd:PRK08787 243 NAEKDALEATKSDIGWGSQIRNYVLDQSR-IKDLRTGIERSDTQKVLDGDLDEFVEASLK 301
prfA PRK00591
peptide chain release factor 1; Validated
 102-440 4.09e-66

peptide chain release factor 1; Validated


Pssm-ID: 234801 [Multi-domain]  Cd Length: 359  Bit Score: 216.10  E-value: 4.09e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  102 ANLQQLEQEITNLESKATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAETivklTEEM--DSTDVSLLEEAM 179
Cdd:PRK00591   6 DKLEALEERYEELEALLSDPEVISDQKRFRKLSKEYAELEPIVEAYREYKQAQEDLEE----AKEMleEESDPEMREMAK 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  180 GIIKELNKSLDKFE--LTQLL--SGPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGI 255
Cdd:PRK00591  82 EELKELEERLEELEeeLKILLlpKDPNDDKNVILEIRAGTGGDEAALFAGDLFRMYSRYAERQGWKVEILSASEGELGGY 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  256 KSATLEIEGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGVEVMPLLPEeaVGIEIPEEDLDISFTRAGGKGGQNVN 335
Cdd:PRK00591 162 KEVIAEISGDGVYSKLKFESGVHRVQRVPATESQGRIHTSAATVAVLPEAEE--VEVEINPKDLRIDTFRSSGAGGQHVN 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  336 KVETAVRITHIPTGVAVRCTEERSQLANKTRALIRLKAKLMVIAEEQRATEIKEIRGDAV----KAEwgqQIRNYVFhPY 411
Cdd:PRK00591 240 TTDSAVRITHLPTGIVVECQDERSQHKNKAKAMKVLRARLYDAERQKAQAEEAATRKSQVgsgdRSE---RIRTYNF-PQ 315

                        330       340
                 ....*....|....*....|....*....
gi 30692908  412 KLVKDVRTGHETSDITSVMDGDLDPFIKA 440
Cdd:PRK00591 316 GRVTDHRINLTLYKLDEVMEGDLDELIDA 344
PCRF pfam03462
PCRF domain; This domain is found in peptide chain release factors.
 107-299 1.18e-62

PCRF domain; This domain is found in peptide chain release factors.


Pssm-ID: 460929 [Multi-domain]  Cd Length: 192  Bit Score: 201.46  E-value: 1.18e-62
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908   107 LEQEITNLESKATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAETIVKLTEEMDstdvsLLEEAMGIIKELN 186
Cdd:pfam03462   1 LEERYEELEALLSDPDVWDDQKRAQKLSKEYSELEPIVEAYREYKQALEDLEEAKELLEDPE-----LAELAEEELEELE 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908   187 KSLDKF--ELTQLLS--GPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKSATLEI 262
Cdd:pfam03462  76 KRLEELeeELKLLLLpkDPNDDKNAILEIRAGAGGDEAALFAGDLFRMYTRYAERKGWKVEVLDYSETEAGGIKEATFEI 155

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 30692908   263 EGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGV 299
Cdd:pfam03462 156 SGEGAYGRLKFESGVHRVQRVPPTESQGRIHTSFATV 192
PrfA COG0216
Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein ...
 104-440 1.39e-60

Protein chain release factor RF1 [Translation, ribosomal structure and biogenesis]; Protein chain release factor RF1 is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 439986 [Multi-domain]  Cd Length: 356  Bit Score: 201.38  E-value: 1.39e-60
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908 104 LQQLEQEITNLESKATDTSFWDDRTKAQETLSSLNDLKDRMRLLSEFKTMVEDAETivklTEEM--DSTDVSLLEEAMGI 181
Cdd:COG0216   6 LEALEERYEELEALLSDPEVISDQKRFRKLSKEYAELEPIVEAYREYKKLLEDIEE----AKELleEESDPEMREMAKEE 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908 182 IKELNKSLDKFE--LTQLL--SGPYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAGIKS 257
Cdd:COG0216  82 LEELEARLEELEeeLKILLlpKDPNDDKNVILEIRAGTGGDEAALFAGDLFRMYSRYAERKGWKVEILSASEGELGGYKE 161

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908 258 ATLEIEGRYAYGYISGEKGTHRIVRQSPFNSKGLRQTSFSGVEVMPllpE-EAVGIEIPEEDLDISFTRAGGKGGQNVNK 336
Cdd:COG0216 162 VIFRISGEGVYSRLKFESGVHRVQRVPETESQGRIHTSAATVAVLP---EaEEVDVEINPKDLRIDTFRSSGAGGQHVNT 238

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908 337 VETAVRITHIPTGVAVRCTEERSQLANKTRALIRLKAKLMVIAEEQRATEIKEIRGDAVkaewG-----QQIRNYVFhPY 411
Cdd:COG0216 239 TDSAVRITHLPTGIVVECQDERSQHKNKAKAMKVLRARLYEAEQQKQQAEIAAERKSQV----GsgdrsERIRTYNF-PQ 313

                       330       340
                ....*....|....*....|....*....
gi 30692908 412 KLVKDVRTGHETSDITSVMDGDLDPFIKA 440
Cdd:COG0216 314 GRVTDHRINLTLYKLDEVMEGDLDELIDA 342
RF-1 pfam00472
RF-1 domain; This domain is found in peptide chain release factors such as RF-1 and RF-2, and ...
 308-418 7.87e-51

RF-1 domain; This domain is found in peptide chain release factors such as RF-1 and RF-2, and a number of smaller proteins of unknown function. This domain contains the peptidyl-tRNA hydrolase activity. The domain contains a highly conserved motif GGQ, where the glutamine is thought to coordinate the water that mediates the hydrolysis.


Pssm-ID: 459823 [Multi-domain]  Cd Length: 111  Bit Score: 167.60  E-value: 7.87e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908   308 EAVGIEIPEEDLDISFTRAGGKGGQNVNKVETAVRITHIPTGVAVRCTEERSQLANKTRALIRLKAKLMVIAEEQRATEI 387
Cdd:pfam00472   1 DEIEIEIDPKDLRIDTFRSSGAGGQHVNKTDSAVRLTHIPTGIVVKCQDERSQHQNREKALKRLRARLYELEEEKEEEKK 80

                          90       100       110
                  ....*....|....*....|....*....|.
gi 30692908   388 KEIRGDAVKAEWGQQIRNYVFHPYKLVKDVR 418
Cdd:pfam00472  81 RRIKSQVGSGDRSEQIRTYNFKPQSRVKDHR 111
PCRF smart00937
This domain is found in peptide chain release factors;
162-274 1.82e-38

This domain is found in peptide chain release factors;


Pssm-ID: 214923 [Multi-domain]  Cd Length: 116  Bit Score: 135.28  E-value: 1.82e-38
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908    162 KLTEEMDstDVSLLEEAMGIIKELN----KSLDKFELTQLLSG-PYDKEGAVVYITAGAGGTDAQDWADMLLRMYMRWGE 236
Cdd:smart00937   1 ELLEEEE--DDEMRELAEEELEELEaeleEELEELLKLLLLPKdPNDDKNAILEIRAGAGGDEAALFAGDLLRMYLRYAE 78

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 30692908    237 KQRYKTKVVEMSNGEEAGIKSATLEIEGRYAYGYISGE 274
Cdd:smart00937  79 RKGWKVEVLDESEGELGGIKEATLKISGEGAYGKLKFE 116
PrfB COG1186
Protein chain release factor PrfB [Translation, ribosomal structure and biogenesis]; Protein ...
 312-433 9.68e-37

Protein chain release factor PrfB [Translation, ribosomal structure and biogenesis]; Protein chain release factor PrfB is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 440799 [Multi-domain]  Cd Length: 140  Bit Score: 131.41  E-value: 9.68e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908 312 IEIPEEDLDISFTRAGGKGGQNVNKVETAVRITH------------IPTGVAVRCTEERSQLANKTRALIRLKAKLMVIA 379
Cdd:COG1186  21 IEIPESDLRIDTYRASGAGGQNVNKVSSAVRLTHdiassslpdsrlTPGGIVVKAQEERSQHQNREDALKRLKALLYEAE 100

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 30692908 380 EEQRATE-IKEIRGDAVKAEWGQQIRNyvfhpykLVKDVRtghetsdiTSVMDGD 433
Cdd:COG1186 101 LEPKERRaTKPTRGSKKRRLWGKQIRS-------MVKDLR--------GNVDDGD 140
release_prfH TIGR03072
putative peptide chain release factor H; Members of this protein family are bacterial proteins ...
 211-396 9.28e-26

putative peptide chain release factor H; Members of this protein family are bacterial proteins homologous to peptide chain release factors 1 (RF-1, product of the prfA gene), and 2 (RF-2, product of the prfB gene). The member from Escherichia coli K-12, designated prfH, appears to be a pseudogene. This class I release factor is always found as the downstream gene of a two-gene operon. [Protein synthesis, Translation factors]


Pssm-ID: 213768  Cd Length: 200  Bit Score: 103.70  E-value: 9.28e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908   211 ITAGAGGTDAQDWADMLLRMYMRWGEKQRYKTKVVEMSNGEEAG-IKSATLEIEGRYAYGYISGEKGTHRIVRQSPFNSK 289
Cdd:TIGR03072   5 LSSAQGPAECCLAVAKALERLTREAAARGVRVEVLEQEPGEVPGtLRSALVSLDGEAAAALADRWEGTLLWICPSPYRPH 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908   290 GLRQTSFSGVEVMPLlPEEAVGIEIPEEDLdisftRAGGKGGQNVNKVETAVRITHIPTGVAVRCTEERSQLANKTRALI 369
Cdd:TIGR03072  85 HRRKNWFIGVQRFSA-SEEATEDEIRFETL-----RSSGPGGQHVNKTESAVRATHLASGISVKVQSERSQHANKRLATL 158

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 30692908   370 RLKAKLMVIAEEQRATEIKE--------IRGDAVK 396
Cdd:TIGR03072 159 LLAVRLADLQQEQAAALRAErrtahhqiERGNPVR 193
PRK09256 PRK09256
aminoacyl-tRNA hydrolase;
312-373 7.93e-13

aminoacyl-tRNA hydrolase;


Pssm-ID: 181730 [Multi-domain]  Cd Length: 138  Bit Score: 65.56  E-value: 7.93e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30692908  312 IEIPEEDLDISFTRAGGKGGQNVNKVETAV-------------------------RIThiPTGVAV-RCTEERSQLANKT 365
Cdd:PRK09256   8 LVIPENELEWRFIRASGPGGQNVNKVSTAVelrfdiaasslpefykerllalaghRIT--KDGVIViKAQEFRSQERNRE 85


                 ....*...
gi 30692908  366 RALIRLKA 373
Cdd:PRK09256  86 DALERLVA 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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