|
Name |
Accession |
Description |
Interval |
E-value |
| PLN03013 |
PLN03013 |
cysteine synthase |
1-429 |
0e+00 |
|
cysteine synthase
Pssm-ID: 178587 [Multi-domain] Cd Length: 429 Bit Score: 745.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 1 MVAMIMASRFNREAKLASQILSTLLGNRSCYTSMAATSSSALLLNPLTSSSSSSTLRRFRCSPEISSLSFSSASDFSLAM 80
Cdd:PLN03013 1 MVAMIMASRFNREAKLASQILSTLLGNRSCYTSMAATSSSALLLNPLTSSSSSSTLRRFRCSPEISSLSFSSASDFSLAM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 81 KRQSRSFADGSERDPSVVCEAVKRETGPDGLNIADNVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYS 160
Cdd:PLN03013 81 KRQSRSFADGSERDPSVVCEAVKRETGPDGLNIADNVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 161 MVTDAEQKGFISPGKSVLVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPAKGMTGAVQKA 240
Cdd:PLN03013 161 MVTDAEQKGFISPGKSVLVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPAKGMTGAVQKA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 241 EEILKNTPDAYMLQQFDNPANPKIHYETTGPEIWDDTKGKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPTESDI 320
Cdd:PLN03013 241 EEILKNTPDAYMLQQFDNPANPKIHYETTGPEIWDDTKGKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPTESDI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 321 LSGGKPGPHKIQGIGAGFIPKNLDQKIMDEVIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPENAGKLIA 400
Cdd:PLN03013 321 LSGGKPGPHKIQGIGAGFIPKNLDQKIMDEVIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPENAGKLIA 400
|
410 420
....*....|....*....|....*....
gi 30695056 401 VVFPSFGeRYLSTPLFQSIREEVEKMQPE 429
Cdd:PLN03013 401 VSLFASG-RDIYTPRCSSLSGKRWRKCSL 428
|
|
| PLN02565 |
PLN02565 |
cysteine synthase |
113-426 |
0e+00 |
|
cysteine synthase
Pssm-ID: 166206 Cd Length: 322 Bit Score: 516.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 113 IADNVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGKSVLVEPTSGNTGIGLAF 192
Cdd:PLN02565 5 IAKDVTELIGKTPLVYLNNVVDGCVARIAAKLEMMEPCSSVKDRIGYSMITDAEEKGLIKPGESVLIEPTSGNTGIGLAF 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 193 IAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPAKGMTGAVQKAEEILKNTPDAYMLQQFDNPANPKIHYETTGPE 272
Cdd:PLN02565 85 MAAAKGYKLIITMPASMSLERRIILLAFGAELVLTDPAKGMKGAVQKAEEILAKTPNSYILQQFENPANPKIHYETTGPE 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 273 IWDDTKGKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPTESDILSGGKPGPHKIQGIGAGFIPKNLDQKIMDEVI 352
Cdd:PLN02565 165 IWKGTGGKVDAFVSGIGTGGTITGAGKYLKEQNPDIKLYGVEPVESAVLSGGKPGPHKIQGIGAGFIPGVLDVDLLDEVV 244
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 30695056 353 AISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPENAGKLIAVVFPSFGERYLSTPLFQSIREEVEKM 426
Cdd:PLN02565 245 QVSSDEAIETAKLLALKEGLLVGISSGAAAAAAIKIAKRPENAGKLIVVIFPSFGERYLSSVLFESVKKEAENM 318
|
|
| cysK |
TIGR01139 |
cysteine synthase A; This model distinguishes cysteine synthase A (CysK) from cysteine ... |
117-416 |
6.82e-165 |
|
cysteine synthase A; This model distinguishes cysteine synthase A (CysK) from cysteine synthase B (CysM). CysM differs in having a broader specificity that also allows the use of thiosulfate to produce cysteine thiosulfonate. [Amino acid biosynthesis, Serine family]
Pssm-ID: 273465 Cd Length: 298 Bit Score: 465.30 E-value: 6.82e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 117 VSQLIGKTPMVYLNSIAkGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGKsVLVEPTSGNTGIGLAFIAAS 196
Cdd:TIGR01139 1 ISELIGNTPLVRLNRIE-GCNANVFVKLEGRNPSGSVKDRIALNMIWDAEKRGLLKPGK-TIVEPTSGNTGIALAMVAAA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 197 RGYRLILTMPASMSMERRVLLKAFGAELVLTDPAKGMTGAVQKAEEILKNTPDAY-MLQQFDNPANPKIHYETTGPEIWD 275
Cdd:TIGR01139 79 RGYKLILTMPETMSIERRKLLKAYGAELVLTPGAEGMKGAIAKAEEIAASTPNSYfMLQQFENPANPEIHRKTTGPEIWR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 276 DTKGKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPTESDILSGGKPGPHKIQGIGAGFIPKNLDQKIMDEVIAIS 355
Cdd:TIGR01139 159 DTDGKLDAFVAGVGTGGTITGVGEVLKEQKPNIKIVAVEPAESPVLSGGKPGPHKIQGIGAGFIPKNLNRSVIDEVITVS 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30695056 356 SEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPEnAGKLIAVVFPSFGERYLSTPLF 416
Cdd:TIGR01139 239 DEEAIETARRLAAEEGILVGISSGAAVAAALKLAKRPE-PDKLIVVILPSTGERYLSTPLF 298
|
|
| PLN00011 |
PLN00011 |
cysteine synthase |
109-429 |
9.82e-165 |
|
cysteine synthase
Pssm-ID: 177651 Cd Length: 323 Bit Score: 466.02 E-value: 9.82e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 109 DGLNIADNVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGKSVLVEPTSGNTGI 188
Cdd:PLN00011 3 DRCLIKNDVTELIGNTPMVYLNNIVDGCVARIAAKLEMMEPCSSVKDRIAYSMIKDAEDKGLITPGKSTLIEATAGNTGI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 189 GLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPAKGMTGAVQKAEEILKNTPDAYMLQQFDNPANPKIHYET 268
Cdd:PLN00011 83 GLACIGAARGYKVILVMPSTMSLERRIILRALGAEVHLTDQSIGLKGMLEKAEEILSKTPGGYIPQQFENPANPEIHYRT 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 269 TGPEIWDDTKGKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPTESDILSGGKPGPHKIQGIGAGFIPKNLDQKIM 348
Cdd:PLN00011 163 TGPEIWRDSAGKVDILVAGVGTGGTATGVGKFLKEKNKDIKVCVVEPVESAVLSGGQPGPHLIQGIGSGIIPFNLDLTIV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 349 DEVIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPENAGKLIAVVFPSFGERYLSTPLFQSIREEVEKMQP 428
Cdd:PLN00011 243 DEIIQVTGEEAIETAKLLALKEGLLVGISSGAAAAAALKVAKRPENAGKLIVVIFPSGGERYLSTKLFESVRYEAENLPI 322
|
.
gi 30695056 429 E 429
Cdd:PLN00011 323 E 323
|
|
| cysKM |
TIGR01136 |
cysteine synthase; This model discriminates cysteine synthases (EC 2.5.1.47) (both CysK and ... |
117-416 |
1.06e-159 |
|
cysteine synthase; This model discriminates cysteine synthases (EC 2.5.1.47) (both CysK and CysM) from cystathionine beta-synthase, a protein found primarily in eukaryotes and carrying a C-terminal CBS domain lacking from this protein. Bacterial proteins lacking the CBS domain but otherwise showing resemblamnce to cystathionine beta-synthases and considerable phylogenetic distance from known cysteine synthases were excluded from the seed and score below the trusted cutoff. [Amino acid biosynthesis, Serine family]
Pssm-ID: 273463 Cd Length: 299 Bit Score: 452.12 E-value: 1.06e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 117 VSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGKsVLVEPTSGNTGIGLAFIAAS 196
Cdd:TIGR01136 1 IEELIGNTPLVRLNRLAPGCDARVLAKLEGFNPSGSVKDRIALSMILDAEKRGLLKPGD-TIIEATSGNTGIALAMVAAA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 197 RGYRLILTMPASMSMERRVLLKAFGAELVLTDPAKGMTGAVQKAEEILKNTPDAYMLQQFDNPANPKIHYETTGPEIWDD 276
Cdd:TIGR01136 80 RGYKLILTMPETMSLERRKLLRAYGAELILTPGEEGMKGAIDKAEELAAETNKYVMLDQFENPANPEAHYKTTGPEIWRD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 277 TKGKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPTESDILSGGKPGPHKIQGIGAGFIPKNLDQKIMDEVIAISS 356
Cdd:TIGR01136 160 TDGRIDHFVAGVGTGGTITGVGRYLKEQNPNIQIVAVEPAESPVLSGGEPGPHKIQGIGAGFIPKILDLSLIDEVITVSD 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 357 EEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPENAGKLIAVVFPSFGERYLSTPLF 416
Cdd:TIGR01136 240 EDAIETARRLAREEGILVGISSGAAVAAALKLAKRLENADKVIVAILPDTGERYLSTGLF 299
|
|
| CysK |
COG0031 |
Cysteine synthase [Amino acid transport and metabolism]; Cysteine synthase is part of the ... |
112-413 |
4.11e-157 |
|
Cysteine synthase [Amino acid transport and metabolism]; Cysteine synthase is part of the Pathway/BioSystem: Cysteine biosynthesis
Pssm-ID: 439802 [Multi-domain] Cd Length: 301 Bit Score: 445.65 E-value: 4.11e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 112 NIADNVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGkSVLVEPTSGNTGIGLA 191
Cdd:COG0031 2 RIYDSILELIGNTPLVRLNRLSPGPGAEIYAKLESFNPGGSVKDRIALSMIEDAEKRGLLKPG-GTIVEATSGNTGIGLA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 192 FIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPAKGMTGAVQKAEEILKNTPDAYMLQQFDNPANPKIHYETTGP 271
Cdd:COG0031 81 MVAAAKGYRLILVMPETMSKERRALLRAYGAEVVLTPGAEGMKGAIDKAEELAAETPGAFWPNQFENPANPEAHYETTGP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 272 EIWDDTKGKVDIFVAgigtggtitgvgRFIKEKNPKTQVIGVEPTESDILSGGKPGPHKIQGIGAGFIPKNLDQKIMDEV 351
Cdd:COG0031 161 EIWEQTDGKVDAFVAgvgtggtitgvgRYLKERNPDIKIVAVEPEGSPLLSGGEPGPHKIEGIGAGFVPKILDPSLIDEV 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 30695056 352 IAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRpENAGKLIAVVFPSFGERYLST 413
Cdd:COG0031 241 ITVSDEEAFAMARRLAREEGILVGISSGAAVAAALRLAKR-LGPGKTIVTILPDSGERYLST 301
|
|
| PLN02556 |
PLN02556 |
cysteine synthase/L-3-cyanoalanine synthase |
110-431 |
6.68e-155 |
|
cysteine synthase/L-3-cyanoalanine synthase
Pssm-ID: 178171 [Multi-domain] Cd Length: 368 Bit Score: 442.86 E-value: 6.68e-155
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 110 GLNIADNVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGKSVLVEPTSGNTGIG 189
Cdd:PLN02556 46 GTKIKTDASQLIGKTPLVYLNKVTEGCGAYIAAKQEMFQPTSSIKDRPALAMIEDAEKKNLITPGKTTLIEPTSGNMGIS 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 190 LAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPAKGMTGAVQKAEEILKNTPDAYMLQQFDNPANPKIHYETT 269
Cdd:PLN02556 126 LAFMAAMKGYKMILTMPSYTSLERRVTMRAFGAELVLTDPTKGMGGTVKKAYELLESTPDAFMLQQFSNPANTQVHFETT 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 270 GPEIWDDTKGKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPTESDILSGGKPGPHKIQGIGAGFIPKNLDQKIMD 349
Cdd:PLN02556 206 GPEIWEDTLGQVDIFVMGIGSGGTVSGVGKYLKSKNPNVKIYGVEPAESNVLNGGKPGPHHITGNGVGFKPDILDMDVME 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 350 EVIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPENAGKLIAVVFPSFGERYLSTPLFQSIREEVEKMQPE 429
Cdd:PLN02556 286 KVLEVSSEDAVNMARELALKEGLMVGISSGANTVAALRLAKMPENKGKLIVTVHPSFGERYLSSVLFQELRKEAENMQPV 365
|
..
gi 30695056 430 RV 431
Cdd:PLN02556 366 SV 367
|
|
| CBS_like |
cd01561 |
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS ... |
122-412 |
8.52e-146 |
|
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of sulfur metabolism characterized by increased levels of the toxic metabolite homocysteine. Cysteine synthase on the other hand catalyzes the last step of cysteine biosynthesis. This subgroup also includes an O-Phosphoserine sulfhydrylase found in hyperthermophilic archaea which produces L-cysteine from sulfide and the more thermostable O-phospho-L-serine.
Pssm-ID: 107204 [Multi-domain] Cd Length: 291 Bit Score: 416.53 E-value: 8.52e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 122 GKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGkSVLVEPTSGNTGIGLAFIAASRGYRL 201
Cdd:cd01561 1 GNTPLVRLNRLSPGTGAEIYAKLEFFNPGGSVKDRIALYMIEDAEKRGLLKPG-TTIIEPTSGNTGIGLAMVAAAKGYRF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 202 ILTMPASMSMERRVLLKAFGAELVLTDPAK--GMTGAVQKAEEILKNTPDAYMLQQFDNPANPKIHYETTGPEIWDDTKG 279
Cdd:cd01561 80 IIVMPETMSEEKRKLLRALGAEVILTPEAEadGMKGAIAKARELAAETPNAFWLNQFENPANPEAHYETTAPEIWEQLDG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 280 KVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPTESDILSGGKPGPHKIQGIGAGFIPKNLDQKIMDEVIAISSEEA 359
Cdd:cd01561 160 KVDAFVAGVGTGGTITGVARYLKEKNPNVRIVGVDPVGSVLFSGGPPGPHKIEGIGAGFIPENLDRSLIDEVVRVSDEEA 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 30695056 360 IETAKQLALKEGLMVGISSGAAAAAAIKVAKRPEnAGKLIAVVFPSFGERYLS 412
Cdd:cd01561 240 FAMARRLAREEGLLVGGSSGAAVAAALKLAKRLG-PGKTIVTILPDSGERYLS 291
|
|
| PRK10717 |
PRK10717 |
cysteine synthase A; Provisional |
112-416 |
3.16e-108 |
|
cysteine synthase A; Provisional
Pssm-ID: 182672 [Multi-domain] Cd Length: 330 Bit Score: 322.58 E-value: 3.16e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 112 NIADNVSQLIGKTPMVYLNSI--AKGCvaNIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGKSVlVEPTSGNTGIG 189
Cdd:PRK10717 2 KIFEDVSDTIGNTPLIRLNRAseATGC--EILGKAEFLNPGGSVKDRAALNIIWDAEKRGLLKPGGTI-VEGTAGNTGIG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 190 LAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLT------DPAKGMTGAVQKAEEILKNTPD-AYMLQQFDNPANP 262
Cdd:PRK10717 79 LALVAAARGYKTVIVMPETQSQEKKDLLRALGAELVLVpaapyaNPNNYVKGAGRLAEELVASEPNgAIWANQFDNPANR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 263 KIHYETTGPEIWDDTKGKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPTESDI----LSG--GKPGPHKIQGIGA 336
Cdd:PRK10717 159 EAHYETTGPEIWEQTDGKVDGFVCAVGTGGTLAGVSRYLKETNPKVKIVLADPTGSALysyyKTGelKAEGSSITEGIGQ 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 337 GFIPKNLDQKIMDEVIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRpENAGKLIAVVFPSFGERYLSTpLF 416
Cdd:PRK10717 239 GRITANLEGAPIDDAIRIPDEEALSTAYRLLEEEGLCLGGSSGINVAAALRLARE-LGPGHTIVTILCDSGERYQSK-LF 316
|
|
| cysM |
PRK11761 |
cysteine synthase CysM; |
119-418 |
1.11e-91 |
|
cysteine synthase CysM;
Pssm-ID: 236972 Cd Length: 296 Bit Score: 279.07 E-value: 1.11e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 119 QLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGkSVLVEPTSGNTGIGLAFIAASRG 198
Cdd:PRK11761 8 DTIGNTPLVKLQRLPPDRGNTILAKLEGNNPAGSVKDRPALSMIVQAEKRGEIKPG-DTLIEATSGNTGIALAMIAAIKG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 199 YRLILTMPASMSMERRVLLKAFGAELVLTDPAKGMTGAVQKAEEILKNTpDAYMLQQFDNPANPKIHYETTGPEIWDDTK 278
Cdd:PRK11761 87 YRMKLIMPENMSQERRAAMRAYGAELILVPKEQGMEGARDLALQMQAEG-EGKVLDQFANPDNPLAHYETTGPEIWRQTE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 279 GKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPTE-SDIlsggkPGphkIQGIGAGFIPKNLDQKIMDEVIAISSE 357
Cdd:PRK11761 166 GRITHFVSSMGTTGTIMGVSRYLKEQNPAVQIVGLQPEEgSSI-----PG---IRRWPEEYLPKIFDASRVDRVLDVSQQ 237
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30695056 358 EAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPENAgkLIAVVFPSFGERYLSTPLFQS 418
Cdd:PRK11761 238 EAENTMRRLAREEGIFCGVSSGGAVAAALRIARENPNA--VIVAIICDRGDRYLSTGVFPA 296
|
|
| cysta_beta |
TIGR01137 |
cystathionine beta-synthase; Members of this family closely resemble cysteine synthase but ... |
113-412 |
1.38e-89 |
|
cystathionine beta-synthase; Members of this family closely resemble cysteine synthase but contain an additional C-terminal CBS domain. The function of any bacterial member included in this family is proposed but not proven. [Amino acid biosynthesis, Serine family]
Pssm-ID: 273464 [Multi-domain] Cd Length: 455 Bit Score: 278.99 E-value: 1.38e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 113 IADNVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGkSVLVEPTSGNTGIGLAF 192
Cdd:TIGR01137 1 ILDNILDLIGNTPLVRLNKVSKGLKCELLAKCEFFNPGGSVKDRIALRMIEDAEASGRLKPG-DTIIEPTSGNTGIGLAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 193 IAASRGYRLILTMPASMSMERRVLLKAFGAELVLT-------DPAKgmtgAVQKAEEILKNTPDAYMLQQFDNPANPKIH 265
Cdd:TIGR01137 80 VAAIKGYKCIIVLPEKMSSEKVDVLRALGAEIVRTptaaafdSPES----HIGVAKRLVREIPGAHILDQYRNPSNPLAH 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 266 YETTGPEIWDDTKGKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPtESDILSGGKP------GPHKIQGIGAGFI 339
Cdd:TIGR01137 156 YDTTGPEILEQCEGKLDMFVAGVGTGGTITGIARYLKESCPGCRIVGADP-EGSILAQPEElnqtgrTPYKVEGIGYDFI 234
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30695056 340 PKNLDQKIMDEVIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPENAGKLIAVVFPSFGERYLS 412
Cdd:TIGR01137 235 PTVLDRKVVDEWIKTDDKESFTMARRLIKEEGLLVGGSSGSAVVAALKAAEDELQEGQRCVVLLPDSIRNYMT 307
|
|
| PALP |
pfam00291 |
Pyridoxal-phosphate dependent enzyme; Members of this family are all pyridoxal-phosphate ... |
117-404 |
1.15e-63 |
|
Pyridoxal-phosphate dependent enzyme; Members of this family are all pyridoxal-phosphate dependent enzymes. This family includes: serine dehydratase EC:4.2.1.13 P20132, threonine dehydratase EC:4.2.1.16, tryptophan synthase beta chain EC:4.2.1.20, threonine synthase EC:4.2.99.2, cysteine synthase EC:4.2.99.8 P11096, cystathionine beta-synthase EC:4.2.1.22, 1-aminocyclopropane-1-carboxylate deaminase EC:4.1.99.4.
Pssm-ID: 459749 [Multi-domain] Cd Length: 295 Bit Score: 206.78 E-value: 1.15e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 117 VSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGfispGKSVLVEPTSGNTGIGLAFIAAS 196
Cdd:pfam00291 1 ISLGIGPTPLVRLPRLSKELGVDVYLKLESLNPTGSFKDRGALNLLLRLKEGE----GGKTVVEASSGNHGRALAAAAAR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 197 RGYRLILTMPASMSMERRVLLKAFGAELVLTDPakGMTGAVQKAEEILKNTPDAYMLQQFDNPANPKIhYETTGPEIWDD 276
Cdd:pfam00291 77 LGLKVTIVVPEDAPPGKLLLMRALGAEVVLVGG--DYDEAVAAARELAAEGPGAYYINQYDNPLNIEG-YGTIGLEILEQ 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 277 TKGKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPTESDILSGG---------KPGPHKIQGIGAGFIPKNLDQKI 347
Cdd:pfam00291 154 LGGDPDAVVVPVGGGGLIAGIARGLKELGPDVRVIGVEPEGAPALARSlaagrpvpvPVADTIADGLGVGDEPGALALDL 233
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30695056 348 M----DEVIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPENAGKLIAVVFP 404
Cdd:pfam00291 234 LdeyvGEVVTVSDEEALEAMRLLARREGIVVEPSSAAALAALKLALAGELKGGDRVVVVLT 294
|
|
| Trp-synth-beta_II |
cd00640 |
Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP) ... |
124-404 |
2.50e-62 |
|
Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan synthase beta chain (Trp-synth_B), cystathionine beta-synthase (CBS), O-acetylserine sulfhydrylase (CS), serine dehydratase (Ser-dehyd), threonine dehydratase (Thr-dehyd), diaminopropionate ammonia lyase (DAL), and threonine synthase (Thr-synth). ACCD catalyzes the conversion of 1-aminocyclopropane-1-carboxylate to alpha-ketobutyrate and ammonia. Tryptophan synthase folds into a tetramer, where the beta chain is the catalytic PLP-binding subunit and catalyzes the formation of L-tryptophan from indole and L-serine. CBS is a tetrameric hemeprotein that catalyzes condensation of serine and homocysteine to cystathionine. CS is a homodimer that catalyzes the formation of L-cysteine from O-acetyl-L-serine. Ser-dehyd catalyzes the conversion of L- or D-serine to pyruvate and ammonia. Thr-dehyd is active as a homodimer and catalyzes the conversion of L-threonine to 2-oxobutanoate and ammonia. DAL is also a homodimer and catalyzes the alpha, beta-elimination reaction of both L- and D-alpha, beta-diaminopropionate to form pyruvate and ammonia. Thr-synth catalyzes the formation of threonine and inorganic phosphate from O-phosphohomoserine.
Pssm-ID: 107202 [Multi-domain] Cd Length: 244 Bit Score: 201.59 E-value: 2.50e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 124 TPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISpgKSVLVEPTSGNTGIGLAFIAASRGYRLIL 203
Cdd:cd00640 1 TPLVRLKRLSKLGGANIYLKLEFLNPTGSFKDRGALNLILLAEEEGKLP--KGVIIESTGGNTGIALAAAAARLGLKCTI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 204 TMPASMSMERRVLLKAFGAELVLTDPakGMTGAVQKAEEILKNTPDAYMLQQFDNPANPKIHYeTTGPEIWDDTKG-KVD 282
Cdd:cd00640 79 VMPEGASPEKVAQMRALGAEVVLVPG--DFDDAIALAKELAEEDPGAYYVNQFDNPANIAGQG-TIGLEILEQLGGqKPD 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 283 IFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPtesdilsggkpgphkiqgigagfipknldqkimdEVIAISSEEAIET 362
Cdd:cd00640 156 AVVVPVGGGGNIAGIARALKELLPNVKVIGVEP----------------------------------EVVTVSDEEALEA 201
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 30695056 363 AKQLALKEGLMVGISSGAAAAAAIKVAKRPeNAGKLIAVVFP 404
Cdd:cd00640 202 IRLLAREEGILVEPSSAAALAAALKLAKKL-GKGKTVVVILT 242
|
|
| PLN02356 |
PLN02356 |
phosphateglycerate kinase |
121-412 |
9.22e-31 |
|
phosphateglycerate kinase
Pssm-ID: 215204 Cd Length: 423 Bit Score: 122.79 E-value: 9.22e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 121 IGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGkSVLVEPTSGNTGIGLAFIAASRGYR 200
Cdd:PLN02356 51 IGNTPLIRINSLSEATGCEILGKCEFLNPGGSVKDRVAVKIIEEALESGQLFPG-GVVTEGSAGSTAISLATVAPAYGCK 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 201 LILTMPASMSMERRVLLKAFGAELVLTDPAK-----------------------------GMTGAVQK------AEEILK 245
Cdd:PLN02356 130 CHVVIPDDVAIEKSQILEALGATVERVRPVSithkdhyvniarrraleanelaskrrkgsETDGIHLEktngciSEEEKE 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 246 NT------PDAYMLQQFDNPANPKIHYETTGPEIWDDTKGKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPTESD 319
Cdd:PLN02356 210 NSlfssscTGGFFADQFENLANFRAHYEGTGPEIWEQTQGNLDAFVAAAGTGGTLAGVSRFLQEKNPNIKCFLIDPPGSG 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 320 ILSG-------------GK----PGPHKIQGIGAGFIPKNLDQKIMDEVIAISSEEAIETAKQLALKEGLMVGISSGAAA 382
Cdd:PLN02356 290 LFNKvtrgvmytreeaeGRrlknPFDTITEGIGINRLTQNFLMAKLDGAFRGTDKEAVEMSRYLLKNDGLFVGSSSAMNC 369
|
330 340 350
....*....|....*....|....*....|
gi 30695056 383 AAAIKVAKRPeNAGKLIAVVFPSFGERYLS 412
Cdd:PLN02356 370 VGAVRVAQSL-GPGHTIVTILCDSGMRHLS 398
|
|
| IlvA |
COG1171 |
Threonine deaminase [Amino acid transport and metabolism]; Threonine deaminase is part of the ... |
114-375 |
2.90e-11 |
|
Threonine deaminase [Amino acid transport and metabolism]; Threonine deaminase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440784 [Multi-domain] Cd Length: 327 Bit Score: 64.29 E-value: 2.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 114 ADNVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMV---TDAE-QKGFISPgksvlvepTSGNTGIG 189
Cdd:COG1171 15 AARIAGVVRRTPLLRSPTLSERLGAEVYLKLENLQPTGSFKLRGAYNALaslSEEErARGVVAA--------SAGNHAQG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 190 LAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPAkgMTGAVQKAEEILKNTpDAYMLQQFDNPanpkiH---- 265
Cdd:COG1171 87 VAYAARLLGIPATIVMPETAPAVKVAATRAYGAEVVLHGDT--YDDAEAAAAELAEEE-GATFVHPFDDP-----Dviag 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 266 YETTGPEIWDDTkGKVD-IFV-----------AGigtggtitgvgrFIKEKNPKTQVIGVEPTESDI----LSGGKP--- 326
Cdd:COG1171 159 QGTIALEILEQL-PDLDaVFVpvggggliagvAA------------ALKALSPDIRVIGVEPEGAAAmyrsLAAGEPvtl 225
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 30695056 327 -GPHKI-QGIGAGFI-PKNLD--QKIMDEVIAISSEEAIETAKQLALKEGLMVG 375
Cdd:COG1171 226 pGVDTIaDGLAVGRPgELTFEilRDLVDDIVTVSEDEIAAAMRLLLERTKIVVE 279
|
|
| Thr-dehyd |
cd01562 |
Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. ... |
114-374 |
5.28e-11 |
|
Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly converted into NH4+. The direct deamination is catalyzed by threonine dehydratase, in which pyridoxal phosphate (PLP) is the prosthetic group. Threonine dehydratase is widely distributed in all three major phylogenetic divisions.
Pssm-ID: 107205 [Multi-domain] Cd Length: 304 Bit Score: 63.27 E-value: 5.28e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 114 ADNVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMV---TDAEQ-KGFISPgksvlvepTSGNTGIG 189
Cdd:cd01562 8 AARIKPVVRRTPLLTSPTLSELLGAEVYLKCENLQKTGSFKIRGAYNKLlslSEEERaKGVVAA--------SAGNHAQG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 190 LAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPakGMTGAVQKAEEILKNTpDAYMLQQFDnpanpkiHYE-- 267
Cdd:cd01562 80 VAYAAKLLGIPATIVMPETAPAAKVDATRAYGAEVVLYGE--DFDEAEAKARELAEEE-GLTFIHPFD-------DPDvi 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 268 ----TTGPEIWDDTKGKVDIFV-----------AGigtggtitgvgrFIKEKNPKTQVIGVEPTESDILS----GGKPGP 328
Cdd:cd01562 150 agqgTIGLEILEQVPDLDAVFVpvggggliagiAT------------AVKALSPNTKVIGVEPEGAPAMAqslaAGKPVT 217
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 30695056 329 HKIQGIGA--------GFIPKNLDQKIMDEVIAISSEEAIETAKQLALKEGLMV 374
Cdd:cd01562 218 LPEVDTIAdglavkrpGELTFEIIRKLVDDVVTVSEDEIAAAMLLLFEREKLVA 271
|
|
| PRK06815 |
PRK06815 |
threonine/serine dehydratase; |
124-402 |
2.16e-07 |
|
threonine/serine dehydratase;
Pssm-ID: 180709 [Multi-domain] Cd Length: 317 Bit Score: 52.39 E-value: 2.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 124 TPMVY--LNSIAKGCvaNIAAKLEIMEPCCSVKDRiGYS---MVTDAEQKgfispgKSVLVEPTSGNTGIGLAFIAASRG 198
Cdd:PRK06815 21 TPLEHspLLSQHTGC--EVYLKCEHLQHTGSFKFR-GASnklRLLNEAQR------QQGVITASSGNHGQGVALAAKLAG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 199 YRLILTMPASMSMERRVLLKAFGAELVL--TDPAKGMTGAVQKAEEILK------NTPDAYMLQQfdnpanpkihyeTTG 270
Cdd:PRK06815 92 IPVTVYAPEQASAIKLDAIRALGAEVRLygGDALNAELAARRAAEQQGKvyispyNDPQVIAGQG------------TIG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 271 PEIWDDTKGKVDIFVAGIGTGGTITGVGrFIKEKNPKTQVIG------------------VEPTESDILSGGKPGphkiq 332
Cdd:PRK06815 160 MELVEQQPDLDAVFVAVGGGGLISGIAT-YLKTLSPKTEIIGcwpanspslytsleageiVEVAEQPTLSDGTAG----- 233
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 333 GIGAGFIPKNLDQKIMDEVIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPEnaGKLIAVV 402
Cdd:PRK06815 234 GVEPGAITFPLCQQLIDQKVLVSEEEIKEAMRLIAETDRWLIEGAAGVALAAALKLAPRYQ--GKKVAVV 301
|
|
| Thr-synth_1 |
cd01563 |
Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last ... |
111-225 |
6.59e-06 |
|
Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants, OPH is an intermediate between the methionine and threonine/isoleucine pathways. Thus threonine synthase competes for OPH with cystathionine-gamma-synthase, the first enzyme in the methionine pathway. These enzymes are in general dimers. Members of this CD, Thr-synth_1, are widely distributed in bacteria, archaea and higher plants.
Pssm-ID: 107206 [Multi-domain] Cd Length: 324 Bit Score: 47.59 E-value: 6.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 111 LNIADNVSQLIGKTPMVYLNSIAK-GCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFispgkSVLVEPTSGNTGIG 189
Cdd:cd01563 10 VTEDDIVSLGEGNTPLVRAPRLGErLGGKNLYVKDEGLNPTGSFKDRGMTVAVSKAKELGV-----KAVACASTGNTSAS 84
|
90 100 110
....*....|....*....|....*....|....*.
gi 30695056 190 LAFIAASRGYRLILTMPASMSMERRVLLKAFGAELV 225
Cdd:cd01563 85 LAAYAARAGIKCVVFLPAGKALGKLAQALAYGATVL 120
|
|
| PRK06381 |
PRK06381 |
threonine synthase; Validated |
139-228 |
6.29e-05 |
|
threonine synthase; Validated
Pssm-ID: 235789 Cd Length: 319 Bit Score: 44.70 E-value: 6.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 139 NIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGF--ISPGksvlvepTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVL 216
Cdd:PRK06381 32 KIYLKFEGANPTGTQKDRIAEAHVRRAMRLGYsgITVG-------TCGNYGASIAYFARLYGLKAVIFIPRSYSNSRVKE 104
|
90
....*....|..
gi 30695056 217 LKAFGAELVLTD 228
Cdd:PRK06381 105 MEKYGAEIIYVD 116
|
|
| ThrC |
COG0498 |
Threonine synthase [Amino acid transport and metabolism]; Threonine synthase is part of the ... |
122-228 |
1.03e-04 |
|
Threonine synthase [Amino acid transport and metabolism]; Threonine synthase is part of the Pathway/BioSystem: Threonine biosynthesis
Pssm-ID: 440264 [Multi-domain] Cd Length: 394 Bit Score: 44.42 E-value: 1.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 122 GKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFIspgksVLVEPTSGNTGIGLAFIAASRGYRL 201
Cdd:COG0498 65 GGTPLVKAPRLADELGKNLYVKEEGHNPTGSFKDRAMQVAVSLALERGAK-----TIVCASSGNGSAALAAYAARAGIEV 139
|
90 100
....*....|....*....|....*...
gi 30695056 202 ILTMPAS-MSMERRVLLKAFGAELVLTD 228
Cdd:COG0498 140 FVFVPEGkVSPGQLAQMLTYGAHVIAVD 167
|
|
| PRK08329 |
PRK08329 |
threonine synthase; Validated |
143-224 |
1.07e-04 |
|
threonine synthase; Validated
Pssm-ID: 236244 [Multi-domain] Cd Length: 347 Bit Score: 44.05 E-value: 1.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 143 KLEIMEPCCSVKDRIGYsmVTDAEQKgfiSPGKSVLVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGA 222
Cdd:PRK08329 77 KLDYLQPTGSFKDRGTY--VTVAKLK---EEGINEVVIDSSGNAALSLALYSLSEGIKVHVFVSYNASKEKISLLSRLGA 151
|
..
gi 30695056 223 EL 224
Cdd:PRK08329 152 EL 153
|
|
| PRK06608 |
PRK06608 |
serine/threonine dehydratase; |
107-259 |
2.06e-04 |
|
serine/threonine dehydratase;
Pssm-ID: 235842 [Multi-domain] Cd Length: 338 Bit Score: 43.22 E-value: 2.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 107 GPDGLNIADN-VSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFIsPGKsvLVEPTSGN 185
Cdd:PRK06608 6 NPQNIAAAHNrIKQYLHLTPIVHSESLNEMLGHEIFFKVESLQKTGAFKVRGVLNHLLELKEQGKL-PDK--IVAYSTGN 82
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 30695056 186 TGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDpakgmtgAVQKAEEILK--NTPDAYMLQQFDNP 259
Cdd:PRK06608 83 HGQAVAYASKLFGIKTRIYLPLNTSKVKQQAALYYGGEVILTN-------TRQEAEEKAKedEEQGFYYIHPSDSD 151
|
|
| PRK05638 |
PRK05638 |
threonine synthase; Validated |
122-389 |
2.24e-04 |
|
threonine synthase; Validated
Pssm-ID: 235539 [Multi-domain] Cd Length: 442 Bit Score: 43.26 E-value: 2.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 122 GKTPMVYLNSIAKGCVaNIAAKLEIMEPCCSVKDRIGYSMVTDAeqkgfISPGKSVLVEPTSGNTGIGLAFIAASRGYRL 201
Cdd:PRK05638 65 GGTPLIRARISEKLGE-NVYIKDETRNPTGSFRDRLATVAVSYG-----LPYAANGFIVASDGNAAASVAAYSARAGKEA 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 202 ILTMPASMSMERRVLLKAFGAELVLTdpAKGMTGAVQKAEEILKntpdaymLQQFDN--PANPKIHYE---TTGPEIWDD 276
Cdd:PRK05638 139 FVVVPRKVDKGKLIQMIAFGAKIIRY--GESVDEAIEYAEELAR-------LNGLYNvtPEYNIIGLEgqkTIAFELWEE 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 277 TkGKVDIFVAGIGTGGTITGVGRF-------IKEKNPKtqVIGVE-----PTESDILsGGKPGPHKIQGIGAGF---IPK 341
Cdd:PRK05638 210 I-NPTHVIVPTGSGSYLYSIYKGFkelleigVIEEIPK--LIAVQtercnPIASEIL-GNKTKCNETKALGLYVknpVMK 285
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 30695056 342 NLDQKIMDE---VIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVA 389
Cdd:PRK05638 286 EYVSEAIKEsggTAVVVNEEEIMAGEKLLAKEGIFAELSSAVVMPALLKLG 336
|
|
| PLN02550 |
PLN02550 |
threonine dehydratase |
95-322 |
2.54e-04 |
|
threonine dehydratase
Pssm-ID: 178165 [Multi-domain] Cd Length: 591 Bit Score: 43.37 E-value: 2.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 95 PSVVCEAVKRETG-----PDGLNIADNVSqliGKTPMVYLNSIAKGCVANIAA--------------------KLEIMEP 149
Cdd:PLN02550 59 LKVSPNSLQYPAGylgavPERTNEAENGS---IPEAMEYLTNILSAKVYDVAIesplqlakklserlgvkvllKREDLQP 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 150 CCSVKDRIGYSMVTD--AEQ--KGFISPgksvlvepTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELV 225
Cdd:PLN02550 136 VFSFKLRGAYNMMAKlpKEQldKGVICS--------SAGNHAQGVALSAQRLGCDAVIAMPVTTPEIKWQSVERLGATVV 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 226 LTDPA--KGMTGAVQKAEEilkntPDAYMLQQFDNPaNPKIHYETTGPEIWDDTKGKVDIFVAGIGTGGTITGVGRFIKE 303
Cdd:PLN02550 208 LVGDSydEAQAYAKQRALE-----EGRTFIPPFDHP-DVIAGQGTVGMEIVRQHQGPLHAIFVPVGGGGLIAGIAAYVKR 281
|
250
....*....|....*....
gi 30695056 304 KNPKTQVIGVEPTESDILS 322
Cdd:PLN02550 282 VRPEVKIIGVEPSDANAMA 300
|
|
| PRK08638 |
PRK08638 |
bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB; |
121-366 |
5.88e-04 |
|
bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB;
Pssm-ID: 236317 [Multi-domain] Cd Length: 333 Bit Score: 41.65 E-value: 5.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 121 IGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGY---SMVTDAE-QKGFISPgksvlvepTSGNTGIGLAFIAAS 196
Cdd:PRK08638 25 IRKTPLPRSNYLSERCKGEIFLKLENMQRTGSFKIRGAFnklSSLTDAEkRKGVVAC--------SAGNHAQGVALSCAL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 197 RGYRLILTMPASMSMERRVLLKAFGAELVLtdpaKGMT--GAVQKAEEILKNTPDAYmLQQFDNPanpKI--HYETTGPE 272
Cdd:PRK08638 97 LGIDGKVVMPKGAPKSKVAATCGYGAEVVL----HGDNfnDTIAKVEEIVEEEGRTF-IPPYDDP---KViaGQGTIGLE 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 273 IWDDTKgKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEP------TESdiLSGGKPGPHKIQGIGA--------GF 338
Cdd:PRK08638 169 ILEDLW-DVDTVIVPIGGGGLIAGIAVALKSINPTIHIIGVQSenvhgmAAS--FYAGEITTHRTTGTLAdgcdvsrpGN 245
|
250 260
....*....|....*....|....*...
gi 30695056 339 IPKNLDQKIMDEVIAISSEEAIETAKQL 366
Cdd:PRK08638 246 LTYEIVRELVDDIVLVSEDEIRNAMKDL 273
|
|
| PRK12483 |
PRK12483 |
threonine dehydratase; Reviewed |
102-321 |
1.07e-03 |
|
threonine dehydratase; Reviewed
Pssm-ID: 237111 [Multi-domain] Cd Length: 521 Bit Score: 41.32 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 102 VKRETGpdgLNIADNVSQLIGKTpmVYLnsiakgcvaniaaKLEIMEPCCSVKDRIGYSMV----TDAEQKGFISPgksv 177
Cdd:PRK12483 34 VARETP---LQRAPNLSARLGNQ--VLL-------------KREDLQPVFSFKIRGAYNKMarlpAEQLARGVITA---- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 178 lvepTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPA--KGMTGAVQKAEEilkntPDAYMLQQ 255
Cdd:PRK12483 92 ----SAGNHAQGVALAAARLGVKAVIVMPRTTPQLKVDGVRAHGGEVVLHGESfpDALAHALKLAEE-----EGLTFVPP 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 30695056 256 FDNPaNPKIHYETTGPEIWDDTKGKVD-IFVAGIGTGGTITGVGrFIKEKNPKTQVIGVEPTESDIL 321
Cdd:PRK12483 163 FDDP-DVIAGQGTVAMEILRQHPGPLDaIFVPVGGGGLIAGIAA-YVKYVRPEIKVIGVEPDDSNCL 227
|
|
| PRK08197 |
PRK08197 |
threonine synthase; Validated |
122-228 |
5.34e-03 |
|
threonine synthase; Validated
Pssm-ID: 181283 [Multi-domain] Cd Length: 394 Bit Score: 38.83 E-value: 5.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695056 122 GKTPMVYLNSIAKGC-VANIAAKLEIMEPCCSVKDRiGYSM-VTDAEQKGFispgkSVLVEPTSGNTGIGLAFIAASRGY 199
Cdd:PRK08197 78 GMTPLLPLPRLGKALgIGRLWVKDEGLNPTGSFKAR-GLAVgVSRAKELGV-----KHLAMPTNGNAGAAWAAYAARAGI 151
|
90 100
....*....|....*....|....*....
gi 30695056 200 RLILTMPASMSMERRVLLKAFGAELVLTD 228
Cdd:PRK08197 152 RATIFMPADAPEITRLECALAGAELYLVD 180
|
|
| PRK06110 |
PRK06110 |
threonine dehydratase; |
173-225 |
6.50e-03 |
|
threonine dehydratase;
Pssm-ID: 235699 Cd Length: 322 Bit Score: 38.44 E-value: 6.50e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 30695056 173 PGKSVLVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELV 225
Cdd:PRK06110 68 PRVRGVISATRGNHGQSVAFAARRHGLAATIVVPHGNSVEKNAAMRALGAELI 120
|
|
| |
