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Conserved domains on  [gi|42570528|ref|NP_850848|]
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alpha/beta-Hydrolases superfamily protein [Arabidopsis thaliana]

Protein Classification

lipase family protein( domain architecture ID 10087743)

lipase class 3 family protein may function as a lipase, catalyzing the hydrolysis of ester bonds of insoluble substrates such a triglycerides, or as a feruloyl esterase, hydrolyzing the feruloyl-arabinose ester bond in arabinoxylans and the feruloyl-galactose ester bond in pectin

CATH:  3.40.50.1820
EC:  3.1.1.-
Gene Ontology:  GO:0016788
PubMed:  9379943|12091482
SCOP:  4000732

Graphical summary

 Zoom to residue level

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Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Lipase_3 cd00519
Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into ...
 38-259 2.76e-62

Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the process of becoming active at the lipid/water interface, although several examples of lipases have been identified that do not undergo interfacial activation . The active site of a lipase contains a catalytic triad consisting of Ser - His - Asp/Glu, but unlike most serine proteases, the active site is buried inside the structure. A "lid" or "flap" covers the active site, making it inaccessible to solvent and substrates. The lid opens during the process of interfacial activation, allowing the lipid substrate access to the active site.


:

Pssm-ID: 238287 [Multi-domain]  Cd Length: 229  Bit Score: 198.85  E-value: 2.76e-62
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  38 NHTLAVTLVEYASAVYESDLTKLFTwtCERCNGLTKDFE---VIEVIFDVEHCLQAYVGVAKDLNAIIIAFRGTqeHSIQ 114
Cdd:cd00519   1 DYEKLKYYAKLAAAAYCVDANILAK--AVVFADIALLNVfspDKLLKTDKQYDTQGYVAVDHDRKTIVIAFRGT--VSLA 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528 115 NWVSDLFWKQLDLNYPDMPDAMVHHGFYSAYHNttLRPAVLDAITRVKKVYGaNINIIVTGHSMGGAMASFCGLDLVVNE 194
Cdd:cd00519  77 DWLTDLDFSPVPLDPPLCSGGKVHSGFYSAYKS--LYNQVLPELKSALKQYP-DYKIIVTGHSLGGALASLLALDLRLRG 153

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 42570528 195 GEENVQVMTFGQPRVGNAAFASYYSLLVPNTFRITHDRDMVPHLPPYYYHfPQKTYHHFPTEVWV 259
Cdd:cd00519 154 PGSDVTVYTFGQPRVGNAAFAEYLESTKGRVYRVVHGNDIVPRLPPGSLT-PPEGYTHVGTEVWI 217
 
Name Accession Description Interval E-value
Lipase_3 cd00519
Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into ...
 38-259 2.76e-62

Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the process of becoming active at the lipid/water interface, although several examples of lipases have been identified that do not undergo interfacial activation . The active site of a lipase contains a catalytic triad consisting of Ser - His - Asp/Glu, but unlike most serine proteases, the active site is buried inside the structure. A "lid" or "flap" covers the active site, making it inaccessible to solvent and substrates. The lid opens during the process of interfacial activation, allowing the lipid substrate access to the active site.


Pssm-ID: 238287 [Multi-domain]  Cd Length: 229  Bit Score: 198.85  E-value: 2.76e-62
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  38 NHTLAVTLVEYASAVYESDLTKLFTwtCERCNGLTKDFE---VIEVIFDVEHCLQAYVGVAKDLNAIIIAFRGTqeHSIQ 114
Cdd:cd00519   1 DYEKLKYYAKLAAAAYCVDANILAK--AVVFADIALLNVfspDKLLKTDKQYDTQGYVAVDHDRKTIVIAFRGT--VSLA 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528 115 NWVSDLFWKQLDLNYPDMPDAMVHHGFYSAYHNttLRPAVLDAITRVKKVYGaNINIIVTGHSMGGAMASFCGLDLVVNE 194
Cdd:cd00519  77 DWLTDLDFSPVPLDPPLCSGGKVHSGFYSAYKS--LYNQVLPELKSALKQYP-DYKIIVTGHSLGGALASLLALDLRLRG 153

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 42570528 195 GEENVQVMTFGQPRVGNAAFASYYSLLVPNTFRITHDRDMVPHLPPYYYHfPQKTYHHFPTEVWV 259
Cdd:cd00519 154 PGSDVTVYTFGQPRVGNAAFAEYLESTKGRVYRVVHGNDIVPRLPPGSLT-PPEGYTHVGTEVWI 217
Lipase_3 pfam01764
Lipase (class 3);
102-240 4.48e-39

Lipase (class 3);


Pssm-ID: 396362 [Multi-domain]  Cd Length: 139  Bit Score: 135.47  E-value: 4.48e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528   102 IIAFRGTqeHSIQNWVSDLFWKQLDLNYPDMPDAMVHHGFYSAYhnTTLRPAVLDAITRVKKVYGaNINIIVTGHSMGGA 181
Cdd:pfam01764   1 VVAFRGT--NSILDWLTDFDFSLTPFKDFFLGGGKVHSGFLSAY--TSVREQVLAELKRLLEKYP-DYSIVVTGHSLGGA 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 42570528   182 MASFCGLDLVVNE--GEENVQVMTFGQPRVGNAAFASYYSLLVP-NTFRITHDRDMVPHLPP 240
Cdd:pfam01764  76 LASLAALDLVENGlrLSSRVTVVTFGQPRVGNLEFAKLHDSQGPkFSYRVVHQRDIVPRLPP 137
Lip2 COG3675
Predicted lipase [Lipid transport and metabolism];
99-263 5.15e-38

Predicted lipase [Lipid transport and metabolism];


Pssm-ID: 442891 [Multi-domain]  Cd Length: 266  Bit Score: 136.81  E-value: 5.15e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  99 NAIIIAFRGTQehSIQNWVSDLFWKQLDLNYpDMPDAMVHHGFYSAYHnttlrpAVLDAITRVKKVYGANINIIVTGHSM 178
Cdd:COG3675  27 DEVIVAFRGTE--SLTDWLTNLNAAQVPYPF-AKTGGKVHRGFYRALQ------SLRELLEDALRPLSPGKRLYVTGHSL 97

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528 179 GGAMASFCGLDLVVNEGEENVQVMTFGQPRVGNAAFASYYSLLVPNTFRITHDRDMVPHLPPYyyhfpQKTYHHFPTEVW 258
Cdd:COG3675  98 GGALATLAAADLERNYIFPVRGLYTFGQPRVGDRSFAKYYNLHVPNSYRIVNNNDIVPLLPPV-----WMGYDHVGKLLW 172


                ....*
gi 42570528 259 VKDFS 263
Cdd:COG3675 173 LDSLR 177
PLN02934 PLN02934
triacylglycerol lipase
 96-275 8.88e-18

triacylglycerol lipase


Pssm-ID: 215504  Cd Length: 515  Bit Score: 84.45  E-value: 8.88e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528   96 KDLNAIIIAFRGTQEHSIQNWVSDLfwkqlDLNYPDMPDA-MVHHGFYSA-------------YHNTTLRPAVLDA---- 157
Cdd:PLN02934 218 KDANLIVISFRGTEPFDADDWGTDF-----DYSWYEIPKVgKVHMGFLEAmglgnrddtttfqTSLQTKATSELKEeesk 292

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  158 ---ITRVKK-VYGA-------------NINIIVTGHSMGGAMASFCGLDLVVNEGEENVQ----VMTFGQPRVGNAAFA- 215
Cdd:PLN02934 293 knlLEMVERsAYYAvrsklksllkehkNAKFVVTGHSLGGALAILFPTVLVLQEETEVMKrllgVYTFGQPRIGNRQLGk 372

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 42570528  216 ---SYYSLLVPNTFRITHDRDMVPHLPpyyyhFPQKT--YHHFPTEVWVKDFSFSNFV-------LFGLEKV 275
Cdd:PLN02934 373 fmeAQLNYPVPRYFRVVYCNDLVPRLP-----YDDKTflYKHFGVCLYYDSRYFGQKMdeepdrnPFGLRNA 439
 
Name Accession Description Interval E-value
Lipase_3 cd00519
Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into ...
 38-259 2.76e-62

Lipase (class 3). Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation," the process of becoming active at the lipid/water interface, although several examples of lipases have been identified that do not undergo interfacial activation . The active site of a lipase contains a catalytic triad consisting of Ser - His - Asp/Glu, but unlike most serine proteases, the active site is buried inside the structure. A "lid" or "flap" covers the active site, making it inaccessible to solvent and substrates. The lid opens during the process of interfacial activation, allowing the lipid substrate access to the active site.


Pssm-ID: 238287 [Multi-domain]  Cd Length: 229  Bit Score: 198.85  E-value: 2.76e-62
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  38 NHTLAVTLVEYASAVYESDLTKLFTwtCERCNGLTKDFE---VIEVIFDVEHCLQAYVGVAKDLNAIIIAFRGTqeHSIQ 114
Cdd:cd00519   1 DYEKLKYYAKLAAAAYCVDANILAK--AVVFADIALLNVfspDKLLKTDKQYDTQGYVAVDHDRKTIVIAFRGT--VSLA 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528 115 NWVSDLFWKQLDLNYPDMPDAMVHHGFYSAYHNttLRPAVLDAITRVKKVYGaNINIIVTGHSMGGAMASFCGLDLVVNE 194
Cdd:cd00519  77 DWLTDLDFSPVPLDPPLCSGGKVHSGFYSAYKS--LYNQVLPELKSALKQYP-DYKIIVTGHSLGGALASLLALDLRLRG 153

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 42570528 195 GEENVQVMTFGQPRVGNAAFASYYSLLVPNTFRITHDRDMVPHLPPYYYHfPQKTYHHFPTEVWV 259
Cdd:cd00519 154 PGSDVTVYTFGQPRVGNAAFAEYLESTKGRVYRVVHGNDIVPRLPPGSLT-PPEGYTHVGTEVWI 217
Lipase_3 pfam01764
Lipase (class 3);
102-240 4.48e-39

Lipase (class 3);


Pssm-ID: 396362 [Multi-domain]  Cd Length: 139  Bit Score: 135.47  E-value: 4.48e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528   102 IIAFRGTqeHSIQNWVSDLFWKQLDLNYPDMPDAMVHHGFYSAYhnTTLRPAVLDAITRVKKVYGaNINIIVTGHSMGGA 181
Cdd:pfam01764   1 VVAFRGT--NSILDWLTDFDFSLTPFKDFFLGGGKVHSGFLSAY--TSVREQVLAELKRLLEKYP-DYSIVVTGHSLGGA 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 42570528   182 MASFCGLDLVVNE--GEENVQVMTFGQPRVGNAAFASYYSLLVP-NTFRITHDRDMVPHLPP 240
Cdd:pfam01764  76 LASLAALDLVENGlrLSSRVTVVTFGQPRVGNLEFAKLHDSQGPkFSYRVVHQRDIVPRLPP 137
Lip2 COG3675
Predicted lipase [Lipid transport and metabolism];
99-263 5.15e-38

Predicted lipase [Lipid transport and metabolism];


Pssm-ID: 442891 [Multi-domain]  Cd Length: 266  Bit Score: 136.81  E-value: 5.15e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  99 NAIIIAFRGTQehSIQNWVSDLFWKQLDLNYpDMPDAMVHHGFYSAYHnttlrpAVLDAITRVKKVYGANINIIVTGHSM 178
Cdd:COG3675  27 DEVIVAFRGTE--SLTDWLTNLNAAQVPYPF-AKTGGKVHRGFYRALQ------SLRELLEDALRPLSPGKRLYVTGHSL 97

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528 179 GGAMASFCGLDLVVNEGEENVQVMTFGQPRVGNAAFASYYSLLVPNTFRITHDRDMVPHLPPYyyhfpQKTYHHFPTEVW 258
Cdd:COG3675  98 GGALATLAAADLERNYIFPVRGLYTFGQPRVGDRSFAKYYNLHVPNSYRIVNNNDIVPLLPPV-----WMGYDHVGKLLW 172


                ....*
gi 42570528 259 VKDFS 263
Cdd:COG3675 173 LDSLR 177
Lipase cd00741
Lipase. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and ...
 139-301 2.09e-37

Lipase. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of becoming active at the lipid/water interface, although several examples of lipases have been identified that do not undergo interfacial activation . The active site of a lipase contains a catalytic triad consisting of Ser - His - Asp/Glu, but unlike most serine proteases, the active site is buried inside the structure. A "lid" or "flap" covers the active site, making it inaccessible to solvent and substrates. The lid opens during the process of interfacial activation, allowing the lipid substrate access to the active site.


Pssm-ID: 238382 [Multi-domain]  Cd Length: 153  Bit Score: 131.85  E-value: 2.09e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528 139 HGFYSAYHNttLRPAVLDAITRVKKVYgANINIIVTGHSMGGAMASFCGLDLVVNEGEENVQVMTFGQPRVGNAAFAS-- 216
Cdd:cd00741   1 KGFYKAARS--LANLVLPLLKSALAQY-PDYKIHVTGHSLGGALAGLAGLDLRGRGLGRLVRVYTFGPPRVGNAAFAEdr 77

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528 217 YYSLLVPNTFRITHDRDMVPHLPPYyyhfpQKTYHHFPTEVWVKDFSFsnfvLFGLEKVCDNTGEDPTCSRSVRGNSISD 296
Cdd:cd00741  78 LDPSDALFVDRIVNDNDIVPRLPPG-----GEGYPHGGAEFYINGGKS----QPGCCKNVLEAVDIDFGNIGLSGNGLCD 148


                ....*
gi 42570528 297 HLRYF 301
Cdd:cd00741 149 HLRYF 153
PLN02934 PLN02934
triacylglycerol lipase
 96-275 8.88e-18

triacylglycerol lipase


Pssm-ID: 215504  Cd Length: 515  Bit Score: 84.45  E-value: 8.88e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528   96 KDLNAIIIAFRGTQEHSIQNWVSDLfwkqlDLNYPDMPDA-MVHHGFYSA-------------YHNTTLRPAVLDA---- 157
Cdd:PLN02934 218 KDANLIVISFRGTEPFDADDWGTDF-----DYSWYEIPKVgKVHMGFLEAmglgnrddtttfqTSLQTKATSELKEeesk 292

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  158 ---ITRVKK-VYGA-------------NINIIVTGHSMGGAMASFCGLDLVVNEGEENVQ----VMTFGQPRVGNAAFA- 215
Cdd:PLN02934 293 knlLEMVERsAYYAvrsklksllkehkNAKFVVTGHSLGGALAILFPTVLVLQEETEVMKrllgVYTFGQPRIGNRQLGk 372

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 42570528  216 ---SYYSLLVPNTFRITHDRDMVPHLPpyyyhFPQKT--YHHFPTEVWVKDFSFSNFV-------LFGLEKV 275
Cdd:PLN02934 373 fmeAQLNYPVPRYFRVVYCNDLVPRLP-----YDDKTflYKHFGVCLYYDSRYFGQKMdeepdrnPFGLRNA 439
PLN02310 PLN02310
triacylglycerol lipase
 47-239 6.54e-17

triacylglycerol lipase


Pssm-ID: 215176  Cd Length: 405  Bit Score: 81.19  E-value: 6.54e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528   47 EYASAVYES---DLTKLFTWTCeRCN--------GLTKD-FEVIEVIF-----DVEHCLQ-------------AYVGVAK 96
Cdd:PLN02310  44 EFAQATYDAfdfDPLSEYCGSC-RYNrhklfetlGLTKHgYKVKKYIYalshvDVPHWLKrsqatwskdsnwmGYVAVSR 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528   97 DLNA-------IIIAFRGTQehSIQNWVSDLfwkQLDLNYPDMPDAMVHHGFYSAYHNT---------TLRPAVLDAITR 160
Cdd:PLN02310 123 DEESqrigrrdIMVAWRGTV--APSEWFLDL---ETKLEHIDNTNVKVQEGFLKIYKSKdestrynklSASEQVMQEVKR 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  161 VKKVY---GANINIIVTGHSMGGAMASFCGLDLVVNEGEENVQVMTFGQPRVGNAAFASYYSLLVPNTFRITHDRDMVPH 237
Cdd:PLN02310 198 LVNFYrgkGEEVSLTVTGHSLGGALALLNAYEAATTIPDLFVSVISFGAPRVGNIAFKEKLNELGVKTLRVVVKQDKVPK 277


                 ..
gi 42570528  238 LP 239
Cdd:PLN02310 278 LP 279
PLN00413 PLN00413
triacylglycerol lipase
 97-253 6.01e-15

triacylglycerol lipase


Pssm-ID: 165792  Cd Length: 479  Bit Score: 75.82  E-value: 6.01e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528   97 DLNAIIIAFRGTQEHSIQNWVSDLfwkqlDLNYPDMPD-AMVHHGFYSAY----------------HNTTLRPAVLDAIT 159
Cdd:PLN00413 198 DPNLIIVSFRGTDPFDADDWCTDL-----DLSWHEVKNvGKIHGGFMKALglpkegwpeeinldetQNATSLLAYYTILR 272

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  160 RVKKVYGAN--INIIVTGHSMGGAMASFCGLDLVVNEGEENVQ----VMTFGQPRVGNAAFASYYSLLVpNTFRITHDR- 232
Cdd:PLN00413 273 HLKEIFDQNptSKFILSGHSLGGALAILFTAVLIMHDEEEMLErlegVYTFGQPRVGDEDFGIFMKDKL-KEFDVKYERy 351

                        170       180
                 ....*....|....*....|....*..
gi 42570528  233 ----DMVPHLPpyyyhFPQKT--YHHF 253
Cdd:PLN00413 352 vycnDMVPRLP-----FDDKTlmFKHF 373
PLN02802 PLN02802
triacylglycerol lipase
 101-240 2.97e-13

triacylglycerol lipase


Pssm-ID: 215432  Cd Length: 509  Bit Score: 70.57  E-value: 2.97e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  101 IIIAFRGTQehSIQNWVSDLFWKQLDLNYPDMPDA-----MVHHGFYSAY-----HNTTLRPAVLDAITRVKKVY-GANI 169
Cdd:PLN02802 253 IVIALRGTA--TCLEWAENLRAGLVPMPGDDDDAGdqeqpKVECGFLSLYktagaHVPSLSESVVGEVRRLMEKYkGEEL 330

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 42570528  170 NIIVTGHSMGGAMASFCGLDLVVNEGEEN-VQVMTFGQPRVGNAAFASYYSLLVPNTFRITHDRDMVPHLPP 240
Cdd:PLN02802 331 SITVTGHSLGAALALLVADELATCVPAAPpVAVFSFGGPRVGNRAFADRLNARGVKVLRVVNAQDVVTRVPG 402
PLN02761 PLN02761
lipase class 3 family protein
 91-239 1.16e-12

lipase class 3 family protein


Pssm-ID: 215406 [Multi-domain]  Cd Length: 527  Bit Score: 68.92  E-value: 1.16e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528   91 YVGVAKDLNA--------IIIAFRGTQEHsiQNWVSDLFWKQLDLNYPDMPDAMVHHGFYSAYHNT---------TLRPA 153
Cdd:PLN02761 196 YVAVATDEEEvkrlgrrdIVIAWRGTVTY--LEWIYDLKDILCSANFGDDPSIKIELGFHDLYTKKedsckfssfSAREQ 273

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  154 VLDAITRVKKVYGAN-----INIIVTGHSMGGAMASFCGLDLV---VNEGEEN-----VQVMTFGQPRVGNAAFASYYSL 220
Cdd:PLN02761 274 VLAEVKRLVEYYGTEeegheISITVTGHSLGASLALVSAYDIAelnLNHVPENnykipITVFSFSGPRVGNLRFKERCDE 353

                        170
                 ....*....|....*....
gi 42570528  221 LVPNTFRITHDRDMVPHLP 239
Cdd:PLN02761 354 LGVKVLRVVNVHDKVPSVP 372
PLN02408 PLN02408
phospholipase A1
 91-239 1.77e-12

phospholipase A1


Pssm-ID: 215228  Cd Length: 365  Bit Score: 67.55  E-value: 1.77e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528   91 YVGVAKDLNAI--------IIAFRGTQehSIQNWVSDLfwKQLDLNYPDMP----------DAMVHHGFYSAYHNTT--- 149
Cdd:PLN02408 102 YVAVCQDKEEIarlgrrdvVIAFRGTA--TCLEWLENL--RATLTRLPNAPtdmngsgdgsGPMVESGFLSLYTSGTamg 177

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  150 --LRPAVLDAITRVKKVYGAN-INIIVTGHSMGGAMASFCGLDLVVNEGEEN-VQVMTFGQPRVGNAAFASYYSLLVPNT 225
Cdd:PLN02408 178 psLQEMVREEIARLLQSYGDEpLSLTITGHSLGAALATLTAYDIKTTFKRAPmVTVISFGGPRVGNRSFRRQLEKQGTKV 257

                        170
                 ....*....|....
gi 42570528  226 FRITHDRDMVPHLP 239
Cdd:PLN02408 258 LRIVNSDDVITKVP 271
PLN02753 PLN02753
triacylglycerol lipase
 90-239 6.41e-12

triacylglycerol lipase


Pssm-ID: 178354  Cd Length: 531  Bit Score: 66.66  E-value: 6.41e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528   90 AYVGVAKDLNA--------IIIAFRGTQehSIQNWVSDL--FWKQLDLNYPDMPD--AMVHHGFYSAYHNT--------- 148
Cdd:PLN02753 210 GYVAVSDDETSrnrlgrrdIAIAWRGTV--TKLEWIADLkdYLKPVSENKIRCPDpaVKVESGFLDLYTDKdttckfakf 287

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  149 TLRPAVLDAITRVKKVYG----ANINIIVTGHSMGGAMASFCGLDLV---VNEGEEN----VQVMTFGQPRVGNAAFASY 217
Cdd:PLN02753 288 SAREQILTEVKRLVEEHGddddSDLSITVTGHSLGGALAILSAYDIAemgLNRSKKGkvipVTVLTYGGPRVGNVRFKDR 367

                        170       180
                 ....*....|....*....|..
gi 42570528  218 YSLLVPNTFRITHDRDMVPHLP 239
Cdd:PLN02753 368 MEELGVKVLRVVNVHDVVPKSP 389
PLN02571 PLN02571
triacylglycerol lipase
 91-243 8.39e-12

triacylglycerol lipase


Pssm-ID: 215309  Cd Length: 413  Bit Score: 66.06  E-value: 8.39e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528   91 YVGVAKDLNA-------IIIAFRGTQEhsIQNWVSDLFW-----KQLDLNYPDMPDamVHHGFYSAY---------HNTT 149
Cdd:PLN02571 130 YVAVATDEGKallgrrdIVIAWRGTVQ--TLEWVNDFEFnlvsaSKIFGESNDQPK--VHQGWYSIYtsdderspfNKTS 205

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  150 LRPAVLDAITR-VKKVYGANINIIVTGHSMGGAMASFCGLDLVVN-----EGEEN----VQVMTFGQPRVGNAAFASYYS 219
Cdd:PLN02571 206 ARDQVLNEVGRlVEKYKDEEISITICGHSLGAALATLNAVDIVANgfnrsKSRPNkscpVTAFVFASPRVGDSDFKKLFS 285

                        170       180
                 ....*....|....*....|....*
gi 42570528  220 LLVP-NTFRITHDRDMVPHLPPYYY 243
Cdd:PLN02571 286 GLKDlRVLRVRNLPDVIPNYPLIGY 310
PLN03037 PLN03037
lipase class 3 family protein; Provisional
 91-239 1.93e-11

lipase class 3 family protein; Provisional


Pssm-ID: 215547  Cd Length: 525  Bit Score: 64.97  E-value: 1.93e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528   91 YVGVAKDLNA-------IIIAFRGTQEHSiqNWVSDLfwkQLDLNYPDMPDAM------VHHGFYSAYHNTT-------- 149
Cdd:PLN03037 220 FVAVSGDRESqrigrrdIVVAWRGTVAPT--EWFMDL---RTSLEPFDCDGDHgknvvkVQSGFLSIYKSKSeltrynkl 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  150 -LRPAVLDAITRVKKVY---GANINIIVTGHSMGGAMAsfcgldlVVNEGE--------ENVQVMTFGQPRVGNAAFASY 217
Cdd:PLN03037 295 sASEQVMEEVKRLVNFFkdrGEEVSLTITGHSLGGALA-------LLNAYEaarsvpalSNISVISFGAPRVGNLAFKEK 367

                        170       180
                 ....*....|....*....|..
gi 42570528  218 YSLLVPNTFRITHDRDMVPHLP 239
Cdd:PLN03037 368 LNELGVKVLRVVNKQDIVPKLP 389
PLN02162 PLN02162
triacylglycerol lipase
 11-239 2.51e-11

triacylglycerol lipase


Pssm-ID: 177821  Cd Length: 475  Bit Score: 64.68  E-value: 2.51e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528   11 AVFTFLVSSSYGRGVLKLKSDDDRPVYNHTLAV--TLVEYASAVYESDLTKlFTWTCErcngLTKDFEVIEViFDVEHCL 88
Cdd:PLN02162 112 ATYTSFIGCSDRRIELDEKIDVGSIEYKSMLSImaSKISYESKPFINSVVK-NTWKMD----LVGNYDFYNA-FQESKLT 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528   89 QAYVGVAKDLNA--IIIAFRGTQEHSIQNWVSDLfwkqlDLNYPDMPD-AMVHHGFYSA-------------------YH 146
Cdd:PLN02162 186 QAFVFKTSSTNPdlIVVSFRGTEPFEAADWCTDL-----DLSWYELKNvGKVHAGFSRAlglqkdggwpkenisllhqYA 260

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  147 NTTLRPAVLDAITRVKkvygaNINIIVTGHSMGGAMASFCGLDLVVNEGEENVQ----VMTFGQPRVGNAAFASYYSLLV 222
Cdd:PLN02162 261 YYTIRQMLRDKLARNK-----NLKYILTGHSLGGALAALFPAILAIHGEDELLDklegIYTFGQPRVGDEDFGEFMKGVV 335

                        250       260
                 ....*....|....*....|.
gi 42570528  223 PNTF----RITHDRDMVPHLP 239
Cdd:PLN02162 336 KKHGieyeRFVYNNDVVPRVP 356
PLN02454 PLN02454
triacylglycerol lipase
 91-239 2.25e-10

triacylglycerol lipase


Pssm-ID: 215249  Cd Length: 414  Bit Score: 61.39  E-value: 2.25e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528   91 YVGVAKDLNA-------IIIAFRGTqehsIQN--WV--------------------SDLFWKQLDLNYPDMPDAMVHHGF 141
Cdd:PLN02454 115 YIAVTSDERTkalgrreIYVAWRGT----TRNyeWVdvlgakltsadpllpgpeqdGVVSGSSSDSDDDDEKGPKVMLGW 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  142 YSAYHNT---------TLRPAVLDAITRVKKVY-GANINIIVTGHSMGGAMASFCGLDLVVNEGEEN---VQVMTFGQPR 208
Cdd:PLN02454 191 LTIYTSDdprspftklSARSQLLAKIKELLERYkDEKLSIVLTGHSLGASLATLAAFDIVENGVSGAdipVTAIVFGSPQ 270

                        170       180       190
                 ....*....|....*....|....*....|....
gi 42570528  209 VGNAAFASYYSLLvPNtFRITHDR---DMVPHLP 239
Cdd:PLN02454 271 VGNKEFNDRFKEH-PN-LKILHVRntiDLIPHYP 302
PLN02324 PLN02324
triacylglycerol lipase
 91-243 1.05e-09

triacylglycerol lipase


Pssm-ID: 177958  Cd Length: 415  Bit Score: 59.26  E-value: 1.05e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528   91 YVGVAKD-------LNAIIIAFRGTQEhsIQNWVSDLfwkqldlNYPDMPDAMVHHG---------------FYSA---- 144
Cdd:PLN02324 117 YIAVATDqgkamlgRRDIVVAWRGTLQ--PYEWANDF-------DFPLESAISVFPVtdpkdnprigsgwldIYTAsdsr 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  145 --YHNTTLRPAVLDAITRVKKVY-GANINIIVTGHSMGGAMASFCGLDLVVNEGEE---NVQ-------VMTFGQPRVGN 211
Cdd:PLN02324 188 spYDTTSAQEQVQGELKRLLELYkNEEISITFTGHSLGAVMSVLSAADLVYGKKNKiniSLQkkqvpitVFAFGSPRIGD 267

                        170       180       190
                 ....*....|....*....|....*....|...
gi 42570528  212 AAFASYYSLLVP-NTFRITHDRDMVPHLPPYYY 243
Cdd:PLN02324 268 HNFKNLVDSLQPlNILRIVNVPDVAPHYPLLLY 300
PLN02719 PLN02719
triacylglycerol lipase
 90-239 1.36e-09

triacylglycerol lipase


Pssm-ID: 178321  Cd Length: 518  Bit Score: 59.33  E-value: 1.36e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528   90 AYVGVAKDLNA---------IIIAFRGTQEHsiQNWVSDL--FWKQLDLNYPDMPDAMV--HHGFYSAYHNT-------- 148
Cdd:PLN02719 195 GYVAVSDDDEAtrcrlgrrdIAIAWRGTVTR--LEWIADLkdFLKPVSGNGFRCPDPAVkaESGFLDLYTDKdtccnfsk 272

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42570528  149 -TLRPAVLDAITRVKKVYG----ANINIIVTGHSMGGAMASFCGLDLV---VNEGEEN----VQVMTFGQPRVGNAAFAS 216
Cdd:PLN02719 273 fSAREQVLTEVKRLVERYGdeegEELSITVTGHSLGGALAVLSAYDVAemgLNRTRKGkvipVTAFTYGGPRVGNIRFKE 352

                        170       180
                 ....*....|....*....|...
gi 42570528  217 YYSLLVPNTFRITHDRDMVPHLP 239
Cdd:PLN02719 353 RIEELGVKVLRVVNEHDVVAKSP 375
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
 126-183 6.30e-03

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 35.96  E-value: 6.30e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 42570528 126 DLNYPDMPDAMVHHGF--YSAYHNTTLRP------AVLDAITRVKKVYGAN-INIIvtGHSMGGAMA 183
Cdd:COG1075  18 AASWAPLAPRLRAAGYpvYALNYPSTNGSiedsaeQLAAFVDAVLAATGAEkVDLV--GHSMGGLVA 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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