|
Name |
Accession |
Description |
Interval |
E-value |
| PLN03014 |
PLN03014 |
carbonic anhydrase |
1-336 |
0e+00 |
|
carbonic anhydrase
Pssm-ID: 178588 [Multi-domain] Cd Length: 347 Bit Score: 660.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 1 MSTAPLSGFFLTSLSPSQSSLQKLSLRTSSTVACLPPASSSSSSSSSSSSRSVPTLIRNEPVFAAPAPIIAPYWSEEMGT 80
Cdd:PLN03014 1 MSTAPLSGFFLTSLSPSQSSLQKLSLRTSSTVACLPPASSSSSSSSSSSSRSVPTLIRNEPVFAAPAPIIAPYWSEEMGT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 81 EAYDEAIEALKKLLIEKEELKTVAAAKVEQITAALQTGTSSDKKAFDPVETIKQGFIKFKKEKYETNPALYGELAKGQSP 160
Cdd:PLN03014 81 EAYDEAIEALKKLLIEKEELKTVAAAKVEQITAALQTGTSSDKKAFDPVETIKQGFIKFKKEKYETNPALYGELAKGQSP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 161 KYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDKVKYGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLMSFP 240
Cdd:PLN03014 161 KYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDKVKYGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLMSFP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 241 LDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFVKGA 320
Cdd:PLN03014 241 LDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFVKGA 320
|
330
....*....|....*.
gi 30678353 321 FELWGLEFGLSETSSV 336
Cdd:PLN03014 321 FELWGLEFGLSETSSV 336
|
|
| beta_CA_cladeB |
cd00884 |
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ... |
135-324 |
1.56e-105 |
|
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.
Pssm-ID: 238449 Cd Length: 190 Bit Score: 306.78 E-value: 1.56e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 135 GFIKFKKEKYETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDK-VKYGGVGAAIEYA 213
Cdd:cd00884 1 GFRRFRKEYFPEERELFEKLAKGQSPKALFIACSDSRVVPALITQTQPGELFVVRNVGNLVPPYEPdGGFHGTSAAIEYA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 214 VLHLKVENIVVIGHSACGGIKGLMSFPlDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSLANLL 293
Cdd:cd00884 81 VAVLKVEHIVVCGHSDCGGIRALLSPE-DLLDKLPFIGKWLRIAEPAKEVVLAELSHADFDDQLRALEKENVLLSLENLL 159
|
170 180 190
....*....|....*....|....*....|.
gi 30678353 294 TYPFVREGLVKGTLALKGGYYDFVKGAFELW 324
Cdd:cd00884 160 TYPFVRERLEAGTLSLHGWYYDIETGELYAY 190
|
|
| CynT |
COG0288 |
Carbonic anhydrase [Inorganic ion transport and metabolism]; |
130-316 |
1.14e-69 |
|
Carbonic anhydrase [Inorganic ion transport and metabolism];
Pssm-ID: 440057 Cd Length: 204 Bit Score: 215.80 E-value: 1.14e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 130 ETIKQGFIKFKKEKYETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDkvkyGGVGAA 209
Cdd:COG0288 5 KRLLEGNRRFVAGKFPQDPERFEELAKGQHPFALVIGCSDSRVPPELIFDQGPGDLFVVRNAGNVVPPYD----PGVLAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 210 IEYAVLHLKVENIVVIGHSACGGIKGLMSfpLDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSL 289
Cdd:COG0288 81 IEYAVEVLGVKLIVVLGHSGCGAVKAALD--GLELEELGLIGNWLRHIRPAVERVRAELPAADGEERLDRLVELNVREQV 158
|
170 180
....*....|....*....|....*..
gi 30678353 290 ANLLTYPFVREGLVKGTLALKGGYYDF 316
Cdd:COG0288 159 ENLRTSPIVREAVAAGKLKVHGWVYDL 185
|
|
| Pro_CA |
pfam00484 |
Carbonic anhydrase; This family includes carbonic anhydrases as well as a family of ... |
162-319 |
3.70e-62 |
|
Carbonic anhydrase; This family includes carbonic anhydrases as well as a family of non-functional homologs related to YbcF.
Pssm-ID: 459828 Cd Length: 156 Bit Score: 195.04 E-value: 3.70e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 162 YMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDkvkyGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLMSfPL 241
Cdd:pfam00484 1 ALIIGCSDSRVPPELIFDTGPGDLFVVRNAGNLVPPYD----LNVLASIEYAVEVLKVKHIVVCGHSGCGAVKAALD-AA 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 30678353 242 DGNNSTDFIEDWVKICLPAKSKVISELGDS-AFEDQCGRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFVKG 319
Cdd:pfam00484 76 GPAELPGFIDNWLRHIRPAVERVAEELESLdDPEERDDALEELNVREQVENLRTFPIVREAVAKGKLKIHGWVYDLETG 154
|
|
| Pro_CA |
smart00947 |
Carbonic anhydrase; Carbonic anhydrases (CA) are zinc metalloenzymes which catalyze the ... |
155-324 |
5.48e-59 |
|
Carbonic anhydrase; Carbonic anhydrases (CA) are zinc metalloenzymes which catalyze the reversible hydration of carbon dioxide. In Escherichia coli, CA (gene cynT) is involved in recycling carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (gene cynS). By this action, it prevents the depletion of cellular bicarbonate. In photosynthetic bacteria and plant chloroplast, CA is essential to inorganic carbon fixation. Prokaryotic and plant chloroplast CA are structurally and evolutionary related and form a family distinct from the one which groups the many different forms of eukaryotic CA's.
Pssm-ID: 214929 [Multi-domain] Cd Length: 154 Bit Score: 186.94 E-value: 5.48e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 155 AKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDkvkyGGVGAAIEYAVLHLKVENIVVIGHSACGGIK 234
Cdd:smart00947 1 AKGQHPKALIIGCSDSRVPPELIFGLGPGDLFVIRNAGNIVPPYD----DGVLASLEYAVEVLGVKEIVVCGHTDCGAVK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 235 GLMsfpldgNNSTDFIEDWVKICLPAKSKVISELGDSAfedqcgRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYY 314
Cdd:smart00947 77 AAL------DDEPGLIDNWLERIRPARERALEELGDVD------ALEELNVRDQVENLRTSPAIREAVAKGKLKVHGWVY 144
|
170
....*....|
gi 30678353 315 DFVKGAFELW 324
Cdd:smart00947 145 DIETGKLEVL 154
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN03014 |
PLN03014 |
carbonic anhydrase |
1-336 |
0e+00 |
|
carbonic anhydrase
Pssm-ID: 178588 [Multi-domain] Cd Length: 347 Bit Score: 660.66 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 1 MSTAPLSGFFLTSLSPSQSSLQKLSLRTSSTVACLPPASSSSSSSSSSSSRSVPTLIRNEPVFAAPAPIIAPYWSEEMGT 80
Cdd:PLN03014 1 MSTAPLSGFFLTSLSPSQSSLQKLSLRTSSTVACLPPASSSSSSSSSSSSRSVPTLIRNEPVFAAPAPIIAPYWSEEMGT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 81 EAYDEAIEALKKLLIEKEELKTVAAAKVEQITAALQTGTSSDKKAFDPVETIKQGFIKFKKEKYETNPALYGELAKGQSP 160
Cdd:PLN03014 81 EAYDEAIEALKKLLIEKEELKTVAAAKVEQITAALQTGTSSDKKAFDPVETIKQGFIKFKKEKYETNPALYGELAKGQSP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 161 KYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDKVKYGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLMSFP 240
Cdd:PLN03014 161 KYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDKVKYGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLMSFP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 241 LDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFVKGA 320
Cdd:PLN03014 241 LDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFVKGA 320
|
330
....*....|....*.
gi 30678353 321 FELWGLEFGLSETSSV 336
Cdd:PLN03014 321 FELWGLEFGLSETSSV 336
|
|
| PLN03019 |
PLN03019 |
carbonic anhydrase |
78-336 |
5.28e-153 |
|
carbonic anhydrase
Pssm-ID: 166660 Cd Length: 330 Bit Score: 432.65 E-value: 5.28e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 78 MGTEAYDEAIEALKKLLIEKEELKTVAAAKVEQITAALQTGTSSDKKAFDPVETIKQGFIKFKKEKYETNPALYGELAKG 157
Cdd:PLN03019 73 MGNESYEDAIEALKKLLIEKDDLKDVAAAKVKKITAELQAASSSDSKSFDPVERIKEGFVTFKKEKYETNPALYGELAKG 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 158 QSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDKVKYGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLM 237
Cdd:PLN03019 153 QSPKYMVFACSDSRVCPSHVLDFHPGDAFVVRNIANMVPPFDKVKYAGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLM 232
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 238 SFPLDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEReAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFV 317
Cdd:PLN03019 233 SFPLDGNNSTDFIEDWVKICLPAKSKVLAESESSAFEDQCGRCER-AVNVSLANLLTYPFVREGVVKGTLALKGGYYDFV 311
|
250
....*....|....*....
gi 30678353 318 KGAFELWGLEFGLSETSSV 336
Cdd:PLN03019 312 NGSFELWELQFGISPVHSI 330
|
|
| PLN00416 |
PLN00416 |
carbonate dehydratase |
78-328 |
5.06e-131 |
|
carbonate dehydratase
Pssm-ID: 177809 Cd Length: 258 Bit Score: 373.99 E-value: 5.06e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 78 MGTEAYDEAIEALKKLLIEKEELKTVAAAKVEQITAALQtgtSSDKKAFDPVETIKQGFIKFKKEKYETNPALYGELAKG 157
Cdd:PLN00416 1 MATESYEAAIKGLNDLLSTKADLGNVAAAKIKALTAELK---ELDSSNSDAIERIKTGFTQFKTEKYLKNSTLFNHLAKT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 158 QSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDKVKYGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLM 237
Cdd:PLN00416 78 QTPKFLVFACSDSRVCPSHILNFQPGEAFVVRNIANMVPPFDQKRHSGVGAAVEYAVVHLKVENILVIGHSCCGGIKGLM 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 238 SFPLD-GNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDF 316
Cdd:PLN00416 158 SIEDDaAPTQSDFIENWVKIGASARNKIKEEHKDLSYDDQCNKCEKEAVNVSLGNLLSYPFVRAEVVKNTLAIRGGHYNF 237
|
250
....*....|..
gi 30678353 317 VKGAFELWGLEF 328
Cdd:PLN00416 238 VKGTFDLWELDF 249
|
|
| beta_CA_cladeB |
cd00884 |
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ... |
135-324 |
1.56e-105 |
|
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.
Pssm-ID: 238449 Cd Length: 190 Bit Score: 306.78 E-value: 1.56e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 135 GFIKFKKEKYETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDK-VKYGGVGAAIEYA 213
Cdd:cd00884 1 GFRRFRKEYFPEERELFEKLAKGQSPKALFIACSDSRVVPALITQTQPGELFVVRNVGNLVPPYEPdGGFHGTSAAIEYA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 214 VLHLKVENIVVIGHSACGGIKGLMSFPlDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSLANLL 293
Cdd:cd00884 81 VAVLKVEHIVVCGHSDCGGIRALLSPE-DLLDKLPFIGKWLRIAEPAKEVVLAELSHADFDDQLRALEKENVLLSLENLL 159
|
170 180 190
....*....|....*....|....*....|.
gi 30678353 294 TYPFVREGLVKGTLALKGGYYDFVKGAFELW 324
Cdd:cd00884 160 TYPFVRERLEAGTLSLHGWYYDIETGELYAY 190
|
|
| CynT |
COG0288 |
Carbonic anhydrase [Inorganic ion transport and metabolism]; |
130-316 |
1.14e-69 |
|
Carbonic anhydrase [Inorganic ion transport and metabolism];
Pssm-ID: 440057 Cd Length: 204 Bit Score: 215.80 E-value: 1.14e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 130 ETIKQGFIKFKKEKYETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDkvkyGGVGAA 209
Cdd:COG0288 5 KRLLEGNRRFVAGKFPQDPERFEELAKGQHPFALVIGCSDSRVPPELIFDQGPGDLFVVRNAGNVVPPYD----PGVLAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 210 IEYAVLHLKVENIVVIGHSACGGIKGLMSfpLDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCEREAVNVSL 289
Cdd:COG0288 81 IEYAVEVLGVKLIVVLGHSGCGAVKAALD--GLELEELGLIGNWLRHIRPAVERVRAELPAADGEERLDRLVELNVREQV 158
|
170 180
....*....|....*....|....*..
gi 30678353 290 ANLLTYPFVREGLVKGTLALKGGYYDF 316
Cdd:COG0288 159 ENLRTSPIVREAVAAGKLKVHGWVYDL 185
|
|
| PLN03006 |
PLN03006 |
carbonate dehydratase |
100-331 |
3.52e-62 |
|
carbonate dehydratase
Pssm-ID: 178583 Cd Length: 301 Bit Score: 200.35 E-value: 3.52e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 100 LKTVAAAKVEQITAAlQTGTSSDKKA-FDPVETIKQGFIKFKKEKYETNPALYGELAKGQSPKYMVFACSDSRVCPSHVL 178
Cdd:PLN03006 53 LQVMASGKTPGLTQE-ANGVAIDRQNnTDVFDDMKQRFLAFKKLKYMDDFEHYKNLADAQAPKFLVIACADSRVCPSAVL 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 179 DFQPGDAFVVRNIANMVPPFDKVKyGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLMSFPLDGnNSTDFIEDWVKICL 258
Cdd:PLN03006 132 GFQPGDAFTVRNIANLVPPYESGP-TETKAALEFSVNTLNVENILVIGHSRCGGIQALMKMEDEG-DSRSFIHNWVVVGK 209
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30678353 259 PAKSKVISELGDSAFEDQCGRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFVKGAFELWGLEFGLS 331
Cdd:PLN03006 210 KAKESTKAVASNLHFDHQCQHCEKASINHSLERLLGYPWIEEKVRQGSLSLHGGYYNFVDCTFEKWTVDYAAS 282
|
|
| Pro_CA |
pfam00484 |
Carbonic anhydrase; This family includes carbonic anhydrases as well as a family of ... |
162-319 |
3.70e-62 |
|
Carbonic anhydrase; This family includes carbonic anhydrases as well as a family of non-functional homologs related to YbcF.
Pssm-ID: 459828 Cd Length: 156 Bit Score: 195.04 E-value: 3.70e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 162 YMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDkvkyGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGLMSfPL 241
Cdd:pfam00484 1 ALIIGCSDSRVPPELIFDTGPGDLFVVRNAGNLVPPYD----LNVLASIEYAVEVLKVKHIVVCGHSGCGAVKAALD-AA 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 30678353 242 DGNNSTDFIEDWVKICLPAKSKVISELGDS-AFEDQCGRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFVKG 319
Cdd:pfam00484 76 GPAELPGFIDNWLRHIRPAVERVAEELESLdDPEERDDALEELNVREQVENLRTFPIVREAVAKGKLKIHGWVYDLETG 154
|
|
| Pro_CA |
smart00947 |
Carbonic anhydrase; Carbonic anhydrases (CA) are zinc metalloenzymes which catalyze the ... |
155-324 |
5.48e-59 |
|
Carbonic anhydrase; Carbonic anhydrases (CA) are zinc metalloenzymes which catalyze the reversible hydration of carbon dioxide. In Escherichia coli, CA (gene cynT) is involved in recycling carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (gene cynS). By this action, it prevents the depletion of cellular bicarbonate. In photosynthetic bacteria and plant chloroplast, CA is essential to inorganic carbon fixation. Prokaryotic and plant chloroplast CA are structurally and evolutionary related and form a family distinct from the one which groups the many different forms of eukaryotic CA's.
Pssm-ID: 214929 [Multi-domain] Cd Length: 154 Bit Score: 186.94 E-value: 5.48e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 155 AKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDkvkyGGVGAAIEYAVLHLKVENIVVIGHSACGGIK 234
Cdd:smart00947 1 AKGQHPKALIIGCSDSRVPPELIFGLGPGDLFVIRNAGNIVPPYD----DGVLASLEYAVEVLGVKEIVVCGHTDCGAVK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 235 GLMsfpldgNNSTDFIEDWVKICLPAKSKVISELGDSAfedqcgRCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYY 314
Cdd:smart00947 77 AAL------DDEPGLIDNWLERIRPARERALEELGDVD------ALEELNVRDQVENLRTSPAIREAVAKGKLKVHGWVY 144
|
170
....*....|
gi 30678353 315 DFVKGAFELW 324
Cdd:smart00947 145 DIETGKLEVL 154
|
|
| PLN02154 |
PLN02154 |
carbonic anhydrase |
124-326 |
2.10e-50 |
|
carbonic anhydrase
Pssm-ID: 215111 Cd Length: 290 Bit Score: 169.54 E-value: 2.10e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 124 KAFDPVETIKQGFIKFKKEKYETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPfdkVKY 203
Cdd:PLN02154 71 TSYDFLDEMRHRFLKFKRQKYLPEIEKFKALAIAQSPKVMVIGCADSRVCPSYVLGFQPGEAFTIRNVANLVTP---VQN 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 204 G--GVGAAIEYAVLHLKVENIVVIGHSACGGIKGLMSFPLDGNNSTDFIEDWVKICLPAKSKVISELGDSAFEDQCGRCE 281
Cdd:PLN02154 148 GptETNSALEFAVTTLQVENIIVMGHSNCGGIAALMSHQNHQGQHSSLVERWVMNGKAAKLRTQLASSHLSFDEQCRNCE 227
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 30678353 282 REAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFVKGAFELWGL 326
Cdd:PLN02154 228 KESIKDSVMNLITYSWIRDRVKRGEVKIHGCYYNLSDCSLEKWRL 272
|
|
| beta_CA |
cd00382 |
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ... |
158-324 |
1.81e-47 |
|
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.
Pssm-ID: 238224 [Multi-domain] Cd Length: 119 Bit Score: 156.12 E-value: 1.81e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 158 QSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDkvkyGGVGAAIEYAVLHLKVENIVVIGHSACGGIKGlm 237
Cdd:cd00382 1 QKPKALIIGCSDSRVPPELIFGLGPGDLFVVRNAGNLVPPYD----LDVLASLEYAVEVLGVKHIIVCGHTDCGAVKA-- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 238 sfpldgnnstdfiedwvkiclpakskviselgdsafedqcgrCEREAVNVSLANLLTYPFVREGLVKGTLALKGGYYDFV 317
Cdd:cd00382 75 ------------------------------------------LVEENVREQVENLRSHPLIQEAVAPGELKVHGWVYDIE 112
|
....*..
gi 30678353 318 KGAFELW 324
Cdd:cd00382 113 TGKLEVL 119
|
|
| beta_CA_cladeA |
cd00883 |
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ... |
138-234 |
4.70e-34 |
|
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.
Pssm-ID: 238448 Cd Length: 182 Bit Score: 123.44 E-value: 4.70e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 138 KFKKEKYETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDKvkygGVGAAIEYAVLHL 217
Cdd:cd00883 3 AWAEEKKAKDPDFFPRLAKGQTPEYLWIGCSDSRVPENTILGLLPGEVFVHRNIANLVSPTDL----NCLSVLQYAVDVL 78
|
90
....*....|....*..
gi 30678353 218 KVENIVVIGHSACGGIK 234
Cdd:cd00883 79 KVKHIIVCGHYGCGGVK 95
|
|
| beta_CA_cladeC |
cd03378 |
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ... |
130-235 |
7.13e-23 |
|
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.
Pssm-ID: 239473 [Multi-domain] Cd Length: 154 Bit Score: 92.97 E-value: 7.13e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 130 ETIKQG---FIKFKKEKYETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPfdkvkygGV 206
Cdd:cd03378 6 ERLKEGnkrFVSGKPLHPDQDLARRRELAKGQKPFAVILSCSDSRVPPEIIFDQGLGDLFVVRVAGNIVDD-------DV 78
|
90 100
....*....|....*....|....*....
gi 30678353 207 GAAIEYAVLHLKVENIVVIGHSACGGIKG 235
Cdd:cd03378 79 LGSLEYAVEVLGVPLVVVLGHESCGAVAA 107
|
|
| PRK10437 |
PRK10437 |
carbonic anhydrase; Provisional |
145-255 |
2.03e-17 |
|
carbonic anhydrase; Provisional
Pssm-ID: 182460 Cd Length: 220 Bit Score: 79.59 E-value: 2.03e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 145 ETNPALYGELAKGQSPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVPPFDKvkygGVGAAIEYAVLHLKVENIVV 224
Cdd:PRK10437 20 EEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDL----NCLSVVQYAVDVLEVEHIII 95
|
90 100 110
....*....|....*....|....*....|....
gi 30678353 225 IGHSACGGIKGLMSFPLDG--NNSTDFIED-WVK 255
Cdd:PRK10437 96 CGHYGCGGVQAAVENPELGliNNWLLHIRDiWFK 129
|
|
| PRK15219 |
PRK15219 |
carbonic anhydrase; Provisional |
103-235 |
2.07e-08 |
|
carbonic anhydrase; Provisional
Pssm-ID: 237927 [Multi-domain] Cd Length: 245 Bit Score: 54.07 E-value: 2.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678353 103 VAAAKVEQIT-AALQTGTSSDKKAFDPV-ETIKQGFIKFKkekyETNPALYGELA------KGQSPKYMVFACSDSRVCP 174
Cdd:PRK15219 29 LAGLGVPQISyAASLTKEERDKMTPDQIiESLKQGNKRFR----SGKPAQHDYLAqkrasaAGQYPAAVILSCIDSRAPA 104
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 30678353 175 SHVLDFQPGDAF---VVRNIANmvppfdkvkyGGVGAAIEYAVLHLKVENIVVIGHSACGGIKG 235
Cdd:PRK15219 105 EIILDTGIGETFnsrVAGNISN----------DDLLGSMEFACAVAGAKVVLVMGHTACGAVKG 158
|
|
| beta_CA_cladeD |
cd03379 |
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ... |
159-231 |
9.89e-08 |
|
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.
Pssm-ID: 239474 Cd Length: 142 Bit Score: 50.33 E-value: 9.89e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 30678353 159 SPKYMVFACSDSRVCPSHVLDFQPGDAFVVRNIANMVppfdkvkyggVGAAIEYAVL---HLKVENIVVIGHSACG 231
Cdd:cd03379 2 ARKLAIVTCMDARLDPEKALGLKLGDAKVIRNAGGRV----------TDDAIRSLVVsvyLLGTREIIVIHHTDCG 67
|
|
| |
