NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|30687770|ref|NP_850309|]
View 

tetratricopeptide repeat (TPR)-containing protein [Arabidopsis thaliana]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 18770923)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  30708253|22404999|21153002
SCOP:  4001344

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 212-512 7.12e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 84.01  E-value: 7.12e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 212 WLQRYVEAQCCVASHAYKGALELFAELLQRFPNNVHLLTETAKVEAIIGKNDEAIMRFEKVRSIDPYTLTSMDEYAMLLQ 291
Cdd:COG2956   8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYL 87

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 292 IKCDYSRLNKLVHDLLSVDHTRAEVFVALSVLWER-KDARTALSYAEKSIRVDERHIPGYIMKGNLLLQAKRPEaaaiaf 370
Cdd:COG2956  88 KAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQeGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYD------ 161

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 371 raaqnlrsdlrsyqglvhsylafgktkEALYTAREAMNAMPQSAKALKLVGDVHAftSSGR-EKAKKFYESGLRLEPGYL 449
Cdd:COG2956 162 ---------------------------EAIEALEKALKLDPDCARALLLLAELYL--EQGDyEEAIAALERALEQDPDYL 212

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30687770 450 GAVLALAELHLMEGRNGDAVSLLERYLKDYADDSLHVKLAQVFAATNMLQDSLSHFQAALRIN 512
Cdd:COG2956 213 PALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALALLERQLRRH 275
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 135-277 2.27e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.41  E-value: 2.27e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 135 TRSLEMNILMAKLHRNSGYNRGAIAFYKECLRQCPYVLEAVIGLAELGVSAKDIissftqtsnRSAKVSLDQ---IDPTR 211
Cdd:COG4783   1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDL---------DEAIVLLHEaleLDPDE 71

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 30687770 212 WLQRYVEAQCCVASHAYKGALELFAELLQRFPNNVHLLTETAKVEAIIGKNDEAIMRFEKVRSIDP 277
Cdd:COG4783  72 PEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 212-512 7.12e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 84.01  E-value: 7.12e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 212 WLQRYVEAQCCVASHAYKGALELFAELLQRFPNNVHLLTETAKVEAIIGKNDEAIMRFEKVRSIDPYTLTSMDEYAMLLQ 291
Cdd:COG2956   8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYL 87

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 292 IKCDYSRLNKLVHDLLSVDHTRAEVFVALSVLWER-KDARTALSYAEKSIRVDERHIPGYIMKGNLLLQAKRPEaaaiaf 370
Cdd:COG2956  88 KAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQeGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYD------ 161

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 371 raaqnlrsdlrsyqglvhsylafgktkEALYTAREAMNAMPQSAKALKLVGDVHAftSSGR-EKAKKFYESGLRLEPGYL 449
Cdd:COG2956 162 ---------------------------EAIEALEKALKLDPDCARALLLLAELYL--EQGDyEEAIAALERALEQDPDYL 212

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30687770 450 GAVLALAELHLMEGRNGDAVSLLERYLKDYADDSLHVKLAQVFAATNMLQDSLSHFQAALRIN 512
Cdd:COG2956 213 PALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALALLERQLRRH 275
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 230-536 2.48e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 69.73  E-value: 2.48e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   230 GALELFAELLQRFPNNVHLLTETAKVEAIIGKNDEAIMRFEKVRSIDPytltsmDEYAMLLQIKCDYSRLNKLVHDL--- 306
Cdd:TIGR02917 517 DAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNP------QEIEPALALAQYYLGKGQLKKALail 590

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   307 -----LSVDHTRAEVFVALSVLwERKDARTALSYAEKSIRVDERHIPGYIMKGNLLLQAKRPEAAAIAFRAAQNLRSDLR 381
Cdd:TIGR02917 591 neaadAAPDSPEAWLMLGRAQL-AAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNT 669

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   382 SYQ-GLVHSYLAFGKTKEALYTAREAMNAMPQSAKALKLVGDVHAfTSSGREKAKKFYESGLRLEPGYLGAVLaLAELHL 460
Cdd:TIGR02917 670 EAQiGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYL-RQKDYPAAIQAYRKALKRAPSSQNAIK-LHRALL 747

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 30687770   461 MEGRNGDAVSLLERYLKDYADDS-LHVKLAQVFAATNMLQDSLSHFQAALRINPQNEAAKKGLDRLEKQMKgiDPDA 536
Cdd:TIGR02917 748 ASGNTAEAVKTLEAWLKTHPNDAvLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELK--DPRA 822
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 135-277 2.27e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.41  E-value: 2.27e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 135 TRSLEMNILMAKLHRNSGYNRGAIAFYKECLRQCPYVLEAVIGLAELGVSAKDIissftqtsnRSAKVSLDQ---IDPTR 211
Cdd:COG4783   1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDL---------DEAIVLLHEaleLDPDE 71

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 30687770 212 WLQRYVEAQCCVASHAYKGALELFAELLQRFPNNVHLLTETAKVEAIIGKNDEAIMRFEKVRSIDP 277
Cdd:COG4783  72 PEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
TPR_19 pfam14559
Tetratricopeptide repeat;
432-488 5.71e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 38.33  E-value: 5.71e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 30687770   432 EKAKKFYESGLRLEPGYLGAVLALAELHLMEGRNGDAVSLLERYLKDYADDSLHVKL 488
Cdd:pfam14559   5 AEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAAL 61
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 389-490 1.27e-03

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 41.33  E-value: 1.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770  389 SYLAFGKTKEALYTAREAMNAMPQSAKALKLVGDVHAftSSGR-EKAKKFYESGLRLEPGYLGAVL-ALAELHLMEGRNG 466
Cdd:PRK11788 189 QALARGDLDAARALLKKALAADPQCVRASILLGDLAL--AQGDyAAAIEALERVEEQDPEYLSEVLpKLMECYQALGDEA 266

                         90       100
                 ....*....|....*....|....
gi 30687770  467 DAVSLLERYLKDYADDSLHVKLAQ 490
Cdd:PRK11788 267 EGLEFLRRALEEYPGADLLLALAQ 290
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 212-512 7.12e-18

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 84.01  E-value: 7.12e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 212 WLQRYVEAQCCVASHAYKGALELFAELLQRFPNNVHLLTETAKVEAIIGKNDEAIMRFEKVRSIDPYTLTSMDEYAMLLQ 291
Cdd:COG2956   8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYL 87

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 292 IKCDYSRLNKLVHDLLSVDHTRAEVFVALSVLWER-KDARTALSYAEKSIRVDERHIPGYIMKGNLLLQAKRPEaaaiaf 370
Cdd:COG2956  88 KAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQeGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYD------ 161

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 371 raaqnlrsdlrsyqglvhsylafgktkEALYTAREAMNAMPQSAKALKLVGDVHAftSSGR-EKAKKFYESGLRLEPGYL 449
Cdd:COG2956 162 ---------------------------EAIEALEKALKLDPDCARALLLLAELYL--EQGDyEEAIAALERALEQDPDYL 212

                       250       260       270       280       290       300
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30687770 450 GAVLALAELHLMEGRNGDAVSLLERYLKDYADDSLHVKLAQVFAATNMLQDSLSHFQAALRIN 512
Cdd:COG2956 213 PALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALALLERQLRRH 275
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 305-528 1.36e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 74.38  E-value: 1.36e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 305 DLLSVDHTRAEVFVAL-SVLWERKDARTALSYAEKSIRVDERHIPGYIMKGNLLLQAKRPEAAAIAFRAAQNLR-SDLRS 382
Cdd:COG2956  33 EALELDPETVEAHLALgNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDpDDAEA 112

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 383 YQGLVHSYLAFGKTKEALYTAREAMNAMPQSAKALKLVGDVhAFTSSGREKAKKFYESGLRLEPGYLGAVLALAELHLME 462
Cdd:COG2956 113 LRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAEL-YLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQ 191

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 30687770 463 GRNGDAVSLLERYLK-DYADDSLHVKLAQVFAATNMLQDSLSHFQAALRINPQNEAAKKGLDRLEKQ 528
Cdd:COG2956 192 GDYEEAIAALERALEqDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERK 258
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 230-536 2.48e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 69.73  E-value: 2.48e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   230 GALELFAELLQRFPNNVHLLTETAKVEAIIGKNDEAIMRFEKVRSIDPytltsmDEYAMLLQIKCDYSRLNKLVHDL--- 306
Cdd:TIGR02917 517 DAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNP------QEIEPALALAQYYLGKGQLKKALail 590

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   307 -----LSVDHTRAEVFVALSVLwERKDARTALSYAEKSIRVDERHIPGYIMKGNLLLQAKRPEAAAIAFRAAQNLRSDLR 381
Cdd:TIGR02917 591 neaadAAPDSPEAWLMLGRAQL-AAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNT 669

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   382 SYQ-GLVHSYLAFGKTKEALYTAREAMNAMPQSAKALKLVGDVHAfTSSGREKAKKFYESGLRLEPGYLGAVLaLAELHL 460
Cdd:TIGR02917 670 EAQiGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYL-RQKDYPAAIQAYRKALKRAPSSQNAIK-LHRALL 747

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 30687770   461 MEGRNGDAVSLLERYLKDYADDS-LHVKLAQVFAATNMLQDSLSHFQAALRINPQNEAAKKGLDRLEKQMKgiDPDA 536
Cdd:TIGR02917 748 ASGNTAEAVKTLEAWLKTHPNDAvLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELK--DPRA 822
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 225-520 4.13e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 68.96  E-value: 4.13e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   225 SHAYKGALELFAELLQRFPNNVHLLTETAKVEAIIGKNDEAIMRFEKVRSIDPYTLTSMDEYAMLLQIKCDYSRLNKLVH 304
Cdd:TIGR02917 444 SGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFE 523

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   305 DLLSVDHTRAEVFVALSVLWERK-DARTALSYAEKSIRVDERHIPGYIMKGNLLLQAKRPEAAAIAFRAAQNL-RSDLRS 382
Cdd:TIGR02917 524 KVLTIDPKNLRAILALAGLYLRTgNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAaPDSPEA 603

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   383 YQGLVHSYLAFGKTKEALYTAREAMNAMPQSAKALKLVGDVHAFTSSgREKAKKFYESGLRLEPGYLGAVLALAELHLME 462
Cdd:TIGR02917 604 WLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKN-YAKAITSLKRALELKPDNTEAQIGLAQLLLAA 682

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 30687770   463 GRNGDAVSLLERYLKDYADDSL-HVKLAQVFAATNMLQDSLSHFQAALRINPQNEAAKK 520
Cdd:TIGR02917 683 KRTESAKKIAKSLQKQHPKAALgFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIK 741
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 356-518 4.22e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 68.87  E-value: 4.22e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 356 LLLQAKRPEAAAIAFRAAQNLRSDLRSYQGLVHSYLAFGKTKEALYTAREAMNAMPQSAKALKLVGDVHAftSSGR-EKA 434
Cdd:COG3914  54 AAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLL--ALGRlEEA 131

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 435 KKFYESGLRLEPGYLGAVLALAELHLMEGRNGDAVSLLERYLKDYADD-SLHVKLAQVFAATNMLQDSLSHFQAALRINP 513
Cdd:COG3914 132 LAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNaEALNNLGNALQDLGRLEEAIAAYRRALELDP 211


                ....*
gi 30687770 514 QNEAA 518
Cdd:COG3914 212 DNADA 216
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 378-515 7.10e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 60.21  E-value: 7.10e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 378 SDLRSYQGLVHSYLAFGKTKEALYTAREAMNAMPQSAKALKLVGDVHAFTssGR-EKAKKFYESGLRLEPGYLGAVLALA 456
Cdd:COG4783   2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQL--GDlDEAIVLLHEALELDPDEPEARLNLG 79

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 457 ELHLMEGRNGDAVSLLERYLKDYADD-SLHVKLAQVFAATNMLQDSLSHFQAALRINPQN 515
Cdd:COG4783  80 LALLKAGDYDEALALLEKALKLDPEHpEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 349-530 1.62e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 62.05  E-value: 1.62e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 349 GYIMKGNLLLQAKRPEAAAIAFRAAQNLRSD-LRSYQGLVHSYLAFGKTKEALYTAREAMNAMPQSAKALKLVGDVhaFT 427
Cdd:COG2956  10 GWYFKGLNYLLNGQPDKAIDLLEEALELDPEtVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQD--YL 87

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 428 SSGR-EKAKKFYESGLRLEPGYLGAVLALAELHLMEGRNGDAVSLLERYLKDYADDS-LHVKLAQVFAATNMLQDSLSHF 505
Cdd:COG2956  88 KAGLlDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAhAYCELAELYLEQGDYDEAIEAL 167

                       170       180
                ....*....|....*....|....*
gi 30687770 506 QAALRINPQNEAAKKGLDRLEKQMK 530
Cdd:COG2956 168 EKALKLDPDCARALLLLAELYLEQG 192
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 332-533 1.66e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.97  E-value: 1.66e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 332 ALSYAEKSIRVDERHIPGYIMKGNLLLQAKRPEAAAIAFRAAQNLRSD-LRSYQGLVHSYLAFGKTKEALYTAREAMNAM 410
Cdd:COG2956  27 AIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDrAEALLELAQDYLKAGLLDRAEELLEKLLELD 106

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 411 PQSAKALKLVGDVHAFTSSGrEKAKKFYESGLRLEPGYLGAVLALAELHLMEGRNGDAVSLLERYLKDYADDS-LHVKLA 489
Cdd:COG2956 107 PDDAEALRLLAEIYEQEGDW-EKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCArALLLLA 185

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....
gi 30687770 490 QVFAATNMLQDSLSHFQAALRINPQNEAAKKGLDRLEKQMKGID 533
Cdd:COG2956 186 ELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPE 229
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
307-547 3.92e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 57.32  E-value: 3.92e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 307 LSVDHTRAEVFVAL-SVLWERKDARTALSYAEKSIRVDERHIPGYIMKGNLLLQAKRPEAAAIAFRAAQNLRSDL-RSYQ 384
Cdd:COG0457   1 LELDPDDAEAYNNLgLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDaEALN 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 385 GLVHSYLAFGKTKEALYTAREAMNAMPQSAKALKLVGDVHAFTssGR-EKAKKFYESGLRLEPGYLGAVLALAELHLMEG 463
Cdd:COG0457  81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLEL--GRyDEAIEAYERALELDPDDADALYNLGIALEKLG 158

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 464 RNGDAVSLLERYLKDYADDSLHVKLAQVFAATNMLQDSLSHFQAALRINPQNEAAKKGLDRLEKQMKGIDPDATDENDEN 543
Cdd:COG0457 159 RYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAAL 238


                ....
gi 30687770 544 DVED 547
Cdd:COG0457 239 ALYQ 242
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 157-479 8.37e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 56.66  E-value: 8.37e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 157 AIAFYKECLRQCPYVLEAVIGLAELGVSAKDIissftqtsNRSAKV--SLDQIDPTRWLQRYVEAQCCVASHAYKGALEL 234
Cdd:COG2956  27 AIDLLEEALELDPETVEAHLALGNLYRRRGEY--------DRAIRIhqKLLERDPDRAEALLELAQDYLKAGLLDRAEEL 98

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 235 FAELLQRFPNNVHLLTETAKVEAIIGKNDEAIMRFEKVRSIDPYTLTSMDEYAMLLQikcdysrlnklvhdllsvdhtra 314
Cdd:COG2956  99 LEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYL----------------------- 155

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 315 evfvalsvlwERKDARTALSYAEKSIRVDERHIPGYIMKGNLLLQAKRPEaaaiafraaqnlrsdlrsyqglvhsylafg 394
Cdd:COG2956 156 ----------EQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYE------------------------------ 195

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 395 ktkEALYTAREAMNAMPQSAKALKLVGDVHAFTSSgREKAKKFYESGLRLEPGyLGAVLALAELHLMEGRNGDAVSLLER 474
Cdd:COG2956 196 ---EAIAALERALEQDPDYLPALPRLAELYEKLGD-PEEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLER 270


                ....*
gi 30687770 475 YLKDY 479
Cdd:COG2956 271 QLRRH 275
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 110-364 8.69e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 56.66  E-value: 8.69e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 110 RFKIASSHFALNETKAAIAEMESV---KTRSLEMNILMAKLHRNSGYNRGAIAFYKECLRQCPYVLEAVIGLAELGVSAK 186
Cdd:COG2956  11 WYFKGLNYLLNGQPDKAIDLLEEAlelDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 187 DIissftqtsNRSAKV--SLDQIDPTRWLQRYVEAQCCVASHAYKGALELFAELLQRFPNNVHLLTETAKVEAIIGKNDE 264
Cdd:COG2956  91 LL--------DRAEELleKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDE 162

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 265 AIMRFEKVRSIDPYTLTSMDEYAMLLQIKCDYSRLNKLVHDLLSVDHTRAEVFVALS-VLWERKDARTALSYAEKSIRVD 343
Cdd:COG2956 163 AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAeLYEKLGDPEEALELLRKALELD 242

                       250       260
                ....*....|....*....|.
gi 30687770 344 ERhIPGYIMKGNLLLQAKRPE 364
Cdd:COG2956 243 PS-DDLLLALADLLERKEGLE 262
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 379-483 8.42e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.16  E-value: 8.42e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 379 DLRSYQGLVHSYLAFGKTKEALYTAREAMNAMPQSAKALKLVGDVHAFtSSGREKAKKFYESGLRLEPGYLGAVLALAEL 458
Cdd:COG4235  16 DAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLA-AGDTEEAEELLERALALDPDNPEALYLLGLA 94

                        90       100
                ....*....|....*....|....*
gi 30687770 459 HLMEGRNGDAVSLLERYLKDYADDS 483
Cdd:COG4235  95 AFQQGDYAEAIAAWQKLLALLPADA 119
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 398-518 8.84e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.16  E-value: 8.84e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 398 EALYTAREAMNAMPQSAKALKLVGDVHAftSSGR-EKAKKFYESGLRLEPGYLGAVLALAELHLMEGRNGDAVSLLERYL 476
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYL--RLGRyDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERAL 78

                        90       100       110       120
                ....*....|....*....|....*....|....*....|...
gi 30687770 477 K-DYADDSLHVKLAQVFAATNMLQDSLSHFQAALRINPQNEAA 518
Cdd:COG4235  79 AlDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPA 121
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 171-539 9.34e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 55.09  E-value: 9.34e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   171 VLEAVIGLAELGVSAKDIISSFTQTSNrsakvsldQIDPTRWLQRYVEAQCCVASHAYKGALELFAELLQRFPNNVHLLT 250
Cdd:TIGR02917 126 ELLALRGLAYLGLGQLELAQKSYEQAL--------AIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALL 197

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   251 ETAKVEAIIGKNDEAIMRFEKVRSIDPYtlTSMDEYA---MLLQIKcDYSRLNKLVHDLLSV--DHTRAEVFVALsVLWE 325
Cdd:TIGR02917 198 LKGDLLLSLGNIELALAAYRKAIALRPN--NIAVLLAlatILIEAG-EFEEAEKHADALLKKapNSPLAHYLKAL-VDFQ 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   326 RKDARTALSYAEKSIRVDERHIPGYIMKGNLLLQAKR-PEAAAIAFRAAQNLRSDLRSYQGLVHSYLAFGKTKEALYTAR 404
Cdd:TIGR02917 274 KKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNlEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLS 353

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   405 EAMNAMPQSAKALKLVGDVH--------------------------------AFTSSGR-EKAKKFYESGLRLEPGYLGA 451
Cdd:TIGR02917 354 PALGLDPDDPAALSLLGEAYlalgdfekaaeylakateldpenaaartqlgiSKLSQGDpSEAIADLETAAQLDPELGRA 433

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   452 VLALAELHLMEGRNGDAVSLLERYLKDYADD-SLHVKLAQVFAATNMLQDSLSHFQAALRINPQNEAAKKGLDRLEKQMK 530
Cdd:TIGR02917 434 DLLLILSYLRSGQFDKALAAAKKLEKKQPDNaSLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEG 513


                  ....*....
gi 30687770   531 GIDpDATDE 539
Cdd:TIGR02917 514 NPD-DAIQR 521
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 432-530 6.61e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 48.65  E-value: 6.61e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 432 EKAKKFYESGLRLEPGYLGAVLALAELHLMEGRNGDAVSLLERYLKDYADDS-LHVKLAQVFAATNMLQDSLSHFQAALR 510
Cdd:COG4783  21 DEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPeARLNLGLALLKAGDYDEALALLEKALK 100

                        90       100
                ....*....|....*....|
gi 30687770 511 INPQNEAAKKGLDRLEKQMK 530
Cdd:COG4783 101 LDPEHPEAYLRLARAYRALG 120
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 231-530 3.72e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.08  E-value: 3.72e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   231 ALELFAELLQRFPNNVHLLTETAKVEAIIGKNDEAIM---RFEKVRSIDPYTLTSMDEYAMLLQikcDYSRLNKLVHDLL 307
Cdd:TIGR02917 314 AYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIAtlsPALGLDPDDPAALSLLGEAYLALG---DFEKAAEYLAKAT 390

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   308 SVDHTRAEVFVALSVL--------WERKDARTALSYAEKSIRVDERHIPGYIMKGNL---LLQAKRPEAAAIAFRAAQNL 376
Cdd:TIGR02917 391 ELDPENAAARTQLGISklsqgdpsEAIADLETAAQLDPELGRADLLLILSYLRSGQFdkaLAAAKKLEKKQPDNASLHNL 470

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   377 RSDLrsyqglvhsYLAFGKTKEALYTAREAMNAMPQSAKALKLVGDVHAftSSGR-EKAKKFYESGLRLEPGYLGAVLAL 455
Cdd:TIGR02917 471 LGAI---------YLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDI--QEGNpDDAIQRFEKVLTIDPKNLRAILAL 539

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 30687770   456 AELHLMEGRNGDAVSLLER-YLKDYADDSLHVKLAQVFAATNMLQDSLSHFQAALRINPQNEAAKKGLDRLEKQMK 530
Cdd:TIGR02917 540 AGLYLRTGNEEEAVAWLEKaAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAG 615
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 385-518 1.28e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.16  E-value: 1.28e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   385 GLVHSYLAFGKTKEALYTAREA-MNAMPQSAKALKLVGDVHaFTSSGREKAKKFYESGLRLEPGYLGAVLALAELHLMEG 463
Cdd:TIGR02917  95 LLARAYLLQGKFQQVLDELPGKtLLDDEGAAELLALRGLAY-LGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAEN 173

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 30687770   464 RNGDAVSLLERYLKDYAD--DSLHVKlAQVFAATNMLQDSLSHFQAALRINPQNEAA 518
Cdd:TIGR02917 174 RFDEARALIDEVLTADPGnvDALLLK-GDLLLSLGNIELALAAYRKAIALRPNNIAV 229
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
390-481 1.33e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.01  E-value: 1.33e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 390 YLAFGKTKEALYTAREAMNAMPQSAKALKLVGDVHAftSSGR-EKAKKFyESGLRLEPGYLGAVLALAELHLMEGRNGDA 468
Cdd:COG3063   2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLL--EQGRyDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEA 78

                        90
                ....*....|...
gi 30687770 469 VSLLERYLKDYAD 481
Cdd:COG3063  79 LAYLERALELDPS 91
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 135-277 2.27e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.41  E-value: 2.27e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 135 TRSLEMNILMAKLHRNSGYNRGAIAFYKECLRQCPYVLEAVIGLAELGVSAKDIissftqtsnRSAKVSLDQ---IDPTR 211
Cdd:COG4783   1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDL---------DEAIVLLHEaleLDPDE 71

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 30687770 212 WLQRYVEAQCCVASHAYKGALELFAELLQRFPNNVHLLTETAKVEAIIGKNDEAIMRFEKVRSIDP 277
Cdd:COG4783  72 PEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 142-558 4.45e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.62  E-value: 4.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   142 ILMAKLHRNSGYNRGAIAFYKECLRQCPYVLEAVIGLAELGVSAKDIISSFTQ-TSNRSAKVSLDQIDPtrwlqryVEAQ 220
Cdd:TIGR02917  26 IEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKElRKALSLGYPKNQVLP-------LLAR 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   221 CCVASHAYKGALELFAEL-LQRFPNNVHLLTETAKVEAIIGKNDEAIMRFEKVRSIDPYTLTSMDEYAMLLQIKCDYSRL 299
Cdd:TIGR02917  99 AYLLQGKFQQVLDELPGKtLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEA 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   300 NKLVHDLLSVD--HTRAEVFVAlSVLWERKDARTALSYAEKSIRVDERHIPGYIMKGNLLLQAKRPEAAAIAF---RAAQ 374
Cdd:TIGR02917 179 RALIDEVLTADpgNVDALLLKG-DLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHAdalLKKA 257

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   375 NLRSDLRSYQGLVHsyLAFGKTKEALYTAREAMNAMPQSAKALKLVGDVHaFTSSGREKAKKFYESGLRLEPGYLGAVLA 454
Cdd:TIGR02917 258 PNSPLAHYLKALVD--FQKKNYEDARETLQDALKSAPEYLPALLLAGASE-YQLGNLEQAYQYLNQILKYAPNSHQARRL 334

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770   455 LAELHLMEGRNGDAVSLLERYLKDYADDSLHVKLA-QVFAATNMLQDSLSHFQAALRINPQNEAA--KKGLDRLekqMKG 531
Cdd:TIGR02917 335 LASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLgEAYLALGDFEKAAEYLAKATELDPENAAArtQLGISKL---SQG 411

                         410       420
                  ....*....|....*....|....*..
gi 30687770   532 iDPDATDENDENDVeDVDGDTEEAELM 558
Cdd:TIGR02917 412 -DPSEAIADLETAA-QLDPELGRADLL 436
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 214-364 4.84e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 43.26  E-value: 4.84e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 214 QRYVEAQCCVASHAYKGALELFAELLQRFPNNVHLLTETAKVEAIIGKNDEAIMRFEKVRSIDPYTLTSMDEYAMLLQIK 293
Cdd:COG4783   6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA 85

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30687770 294 CDYSRlnklvhdllsvdhtraevfvalsvlwerkdartALSYAEKSIRVDERHIPGYIMKGNLLLQAKRPE 364
Cdd:COG4783  86 GDYDE---------------------------------ALALLEKALKLDPEHPEAYLRLARAYRALGRPD 123
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 356-477 1.30e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.64  E-value: 1.30e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 356 LLLQAKRPEAAAIAFRAAQNLRSDLRSYQGLVHSYLAFGKTKEALYTAREAMNAMPQSAKALKLVGDVHAftSSGR-EKA 434
Cdd:COG5010  30 ALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYS--RSGDkDEA 107

                        90       100       110       120
                ....*....|....*....|....*....|....*....|...
gi 30687770 435 KKFYESGLRLEPGYLGAVLALAELHLMEGRNGDAVSLLERYLK 477
Cdd:COG5010 108 KEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 213-364 2.26e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 44.21  E-value: 2.26e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 213 LQRYVEAQCCVASHAYKGALELFAELLQRFPNNVHLLTETAKVEAIIGKNDEAIMRFEKVRSIDPYTLTSMDEYAMLLQI 292
Cdd:COG3914  45 LLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLA 124

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30687770 293 KCDYSRLNKLVHDLLSVDHTRAEVFVAL-SVLWERKDARTALSYAEKSIRVDERHIPGYIMKGNLLLQAKRPE 364
Cdd:COG3914 125 LGRLEEALAALRRALALNPDFAEAYLNLgEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLE 197
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 222-392 3.88e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 43.44  E-value: 3.88e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 222 CVASHAYKGALELFAELLQRFPNNVHLLTETAKVEAIIGKNDEAIMRFEKVRSIDPYTLTSMDEYAMLLQIKCDYSRLNK 301
Cdd:COG3914  88 LQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIA 167

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 302 LVHDLLSVDHTRAEVFVALSVLWER-KDARTALSYAEKSIRVDERHIPGYIMKGNLLLQAKRPEAAAIAFRAAQNLRSDL 380
Cdd:COG3914 168 ALRRALELDPDNAEALNNLGNALQDlGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGP 247

                       170
                ....*....|..
gi 30687770 381 RSYQGLVHSYLA 392
Cdd:COG3914 248 SELSPFALLYLP 259
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
432-513 4.92e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.38  E-value: 4.92e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 432 EKAKKFYESGLRLEPGYLGAVLALAELHLMEGRNGDAVSLLERYLKDYADDSLHVKLAQVFAATNMLQDSLSHFQAALRI 511
Cdd:COG3063   9 EEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALEL 88


                ..
gi 30687770 512 NP 513
Cdd:COG3063  89 DP 90
TPR_19 pfam14559
Tetratricopeptide repeat;
432-488 5.71e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 38.33  E-value: 5.71e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 30687770   432 EKAKKFYESGLRLEPGYLGAVLALAELHLMEGRNGDAVSLLERYLKDYADDSLHVKL 488
Cdd:pfam14559   5 AEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAAL 61
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 432-513 6.21e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 40.71  E-value: 6.21e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 432 EKAKKFYESGLRLEPGYLGAVLALAELHLMEGRNGDAVSLLERYLKDYADDS-LHVKLAQVFAATNMLQDSLSHFQAALR 510
Cdd:COG5010  71 EESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPnAYSNLAALLLSLGQDDEAKAALQRALG 150


                ...
gi 30687770 511 INP 513
Cdd:COG5010 151 TSP 153
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 451-527 9.73e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.20  E-value: 9.73e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 451 AVLALAELHLMEGRNGDAVSLLERYLKDYADDSL----HVKLAQVFAATNMLQDSLSHFQAALRINPQNEAAKKGLDRLE 526
Cdd:COG1729  32 ALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdaLLKLGLSYLELGDYDKARATLEELIKKYPDSEAAKEARARLA 111


                .
gi 30687770 527 K 527
Cdd:COG1729 112 R 112
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 389-490 1.27e-03

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 41.33  E-value: 1.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770  389 SYLAFGKTKEALYTAREAMNAMPQSAKALKLVGDVHAftSSGR-EKAKKFYESGLRLEPGYLGAVL-ALAELHLMEGRNG 466
Cdd:PRK11788 189 QALARGDLDAARALLKKALAADPQCVRASILLGDLAL--AQGDyAAAIEALERVEEQDPEYLSEVLpKLMECYQALGDEA 266

                         90       100
                 ....*....|....*....|....
gi 30687770  467 DAVSLLERYLKDYADDSLHVKLAQ 490
Cdd:PRK11788 267 EGLEFLRRALEEYPGADLLLALAQ 290
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 200-296 8.22e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 36.91  E-value: 8.22e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 200 AKVSLDQIDPTRWLQRyveAQCCVASHAYKGALELFAELLQRFPNNVHLLTETAKVEAIIGKNDEAIMRFEKVRSIDPYT 279
Cdd:COG4235   8 QALAANPNDAEGWLLL---GRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDN 84

                        90
                ....*....|....*..
gi 30687770 280 LTSMDEYAMLLQIKCDY 296
Cdd:COG4235  85 PEALYLLGLAAFQQGDY 101
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
322-411 8.26e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 35.92  E-value: 8.26e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30687770 322 VLWERKDARTALSYAEKSIRVDERHIPGYIMKGNLLLQAKRPEAAAIAFRAAQNLRSDLRSYQGLVHSYLAFGKTKEALY 401
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIALEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                        90
                ....*....|
gi 30687770 402 TAREAMNAMP 411
Cdd:COG3063  81 YLERALELDP 90
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 453-516 9.24e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 35.00  E-value: 9.24e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 30687770   453 LALAELHLMEGRNGDAVSLLERYLKDYADDSLHV----KLAQVFAATNMLQDSLSHFQAALRINPQNE 516
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFPESPDAAaallLLGLAALRQGRLAEAAAAYRAALRAAPGDP 68
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH