|
Name |
Accession |
Description |
Interval |
E-value |
| 60KD_IMP |
pfam02096 |
60Kd inner membrane protein; |
140-341 |
8.67e-65 |
|
60Kd inner membrane protein;
Pssm-ID: 460443 [Multi-domain] Cd Length: 187 Bit Score: 203.09 E-value: 8.67e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 140 YGFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAGNQERIQLETSRLYKQAGVNPLAGCLPTLATIPVW 219
Cdd:pfam02096 1 YGLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYKDDRQKLQQEMMKLYKKEGVNPLGGCLPMLIQMPIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 220 IGLYQALSNvANEGLFTEGFFWIPSLGGPTSIAarqsgsgiswlfpfvdghpplgwydTVAYLVLPVLLIASQYVSMEIM 299
Cdd:pfam02096 81 IALYRVLRN-SIELRHAPFFLWIADLSAPDPIS-------------------------ILHYYILPILMGVTMFLQQKLT 134
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 30684018 300 KPPQTDDPAQKNTLLVfkFLPLMIGYFALSVPSGLSIYWLVS 341
Cdd:pfam02096 135 PAPQDQPPQMKMMMLY--FMPLMFLFFFLNFPAGLVLYWVVS 174
|
|
| YidC |
COG0706 |
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis]; |
111-341 |
1.40e-64 |
|
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440470 [Multi-domain] Cd Length: 212 Bit Score: 203.81 E-value: 1.40e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 111 GWFGFISDAMELVLKILKDGLSAvhvpyaYGFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAGNQERI 190
Cdd:COG0706 4 GWFGFIAKPLFWLLNFLHSLVGN------WGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYKDDPQKL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 191 QLETSRLYKQAGVNPLAGCLPTLATIPVWIGLYQALSNVANegLFTEGFFWIPSLGGPTSIaarqsgsgiswlfpfvdgh 270
Cdd:COG0706 78 QQEMMKLYKEEGVNPLGGCLPMLIQMPIFIALYRVLRNSIE--LRHAPFLGIPDLSAPDPY------------------- 136
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30684018 271 pplgwydtvaYLVLPVLLIASQYVSMEIMkPPQTDDPAQKntlLVFKFLPLMIGYFALSVPSGLSIYWLVS 341
Cdd:COG0706 137 ----------YIFLPILMGVTMFLQQKLN-PAPAQDPQQK---KMMYIMPLMFLFFFLSFPAGLVLYWVVS 193
|
|
| 5TM_YidC_Alb3 |
cd20070 |
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ... |
141-341 |
9.49e-59 |
|
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410994 [Multi-domain] Cd Length: 181 Bit Score: 187.59 E-value: 9.49e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 141 GFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAGNQERIQLETSRLYKQAGVNPLAGCLPTLATIPVWI 220
Cdd:cd20070 1 GLAIILLTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYKDDKQKLQQEMMKLYKEHGVNPLGGCLPLLIQMPIFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 221 GLYQALSNVanEGLFTEGFFW-IPSLGGPTSiaarqsgsgiswlfpfvdghpplgwydtvaYLVLPVLLIASQYVSMEIM 299
Cdd:cd20070 81 ALYQVLRNS--IELRGAPFLWwILDLSAPDP------------------------------YYILPILMGVTMFLQQKLT 128
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 30684018 300 KPPQTDDPAQKNTLLvfKFLPLMIGYFALSVPSGLSIYWLVS 341
Cdd:cd20070 129 PTPTDDQAPQQKMMM--YFMPVMFTFIFLSFPSGLVLYWLVS 168
|
|
| yidC_oxa1_cterm |
TIGR03592 |
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ... |
140-341 |
3.31e-56 |
|
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274665 [Multi-domain] Cd Length: 179 Bit Score: 181.14 E-value: 3.31e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 140 YGFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAGNQERIQLETSRLYKQAGVNPLAGCLPTLATIPVW 219
Cdd:TIGR03592 2 WGLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYKEDPQKLQQEMMKLYKEEGVNPLGGCLPLLIQMPIF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 220 IGLYQALSNvaNEGLFTEGFFWIPSLGGPTsiaarqsgsgiswlfpfvdghpplgwydtvAYLVLPVLLIASQYVSMEIM 299
Cdd:TIGR03592 82 IALYQVLLR--SIELRHAPFLWIIDLSSPD------------------------------PYYILPILMGVTMFLQQKLS 129
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 30684018 300 KPPQTDDPAQKNTLlvfKFLPLMIGYFALSVPSGLSIYWLVS 341
Cdd:TIGR03592 130 PKGPPDPAQQKMMM---YFMPLMFLFFFLSFPAGLVLYWVVS 168
|
|
| PRK01318 |
PRK01318 |
membrane protein insertase; Provisional |
111-341 |
2.53e-46 |
|
membrane protein insertase; Provisional
Pssm-ID: 234942 [Multi-domain] Cd Length: 521 Bit Score: 164.66 E-value: 2.53e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 111 GWFGFISDAMELVLKILKDGLSAvhvpyaYGFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAGNQERI 190
Cdd:PRK01318 300 GWLWFITKPLFWLLDFLHSFVGN------WGWAIILLTIIVKLLLFPLTYKSYVSMAKMKVLQPKMQELKEKYKDDPQKM 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 191 QLETSRLYKQAGVNPLAGCLPTLATIPVWIGLYQALsnvaneglftegffwipslggPTSIAARQSgsgiswlfPFvdgh 270
Cdd:PRK01318 374 QQEMMELYKKEKVNPLGGCLPILIQIPIFFALYKVL---------------------LVSIELRHA--------PF---- 420
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 271 ppLGW------YDTV---AYLVLPVLLIASQYVSMeIMKPPQTdDPAQKNtllVFKFLPLMIGYFALSVPSGLSIYWLVS 341
Cdd:PRK01318 421 --IGWihdlsaPDPYfilHIGLLPILMGITMFLQQ-KLNPTPT-DPMQAK---IMKFMPLIFTFFFLSFPAGLVLYWIVN 493
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| 60KD_IMP |
pfam02096 |
60Kd inner membrane protein; |
140-341 |
8.67e-65 |
|
60Kd inner membrane protein;
Pssm-ID: 460443 [Multi-domain] Cd Length: 187 Bit Score: 203.09 E-value: 8.67e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 140 YGFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAGNQERIQLETSRLYKQAGVNPLAGCLPTLATIPVW 219
Cdd:pfam02096 1 YGLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYKDDRQKLQQEMMKLYKKEGVNPLGGCLPMLIQMPIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 220 IGLYQALSNvANEGLFTEGFFWIPSLGGPTSIAarqsgsgiswlfpfvdghpplgwydTVAYLVLPVLLIASQYVSMEIM 299
Cdd:pfam02096 81 IALYRVLRN-SIELRHAPFFLWIADLSAPDPIS-------------------------ILHYYILPILMGVTMFLQQKLT 134
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 30684018 300 KPPQTDDPAQKNTLLVfkFLPLMIGYFALSVPSGLSIYWLVS 341
Cdd:pfam02096 135 PAPQDQPPQMKMMMLY--FMPLMFLFFFLNFPAGLVLYWVVS 174
|
|
| YidC |
COG0706 |
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis]; |
111-341 |
1.40e-64 |
|
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440470 [Multi-domain] Cd Length: 212 Bit Score: 203.81 E-value: 1.40e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 111 GWFGFISDAMELVLKILKDGLSAvhvpyaYGFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAGNQERI 190
Cdd:COG0706 4 GWFGFIAKPLFWLLNFLHSLVGN------WGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYKDDPQKL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 191 QLETSRLYKQAGVNPLAGCLPTLATIPVWIGLYQALSNVANegLFTEGFFWIPSLGGPTSIaarqsgsgiswlfpfvdgh 270
Cdd:COG0706 78 QQEMMKLYKEEGVNPLGGCLPMLIQMPIFIALYRVLRNSIE--LRHAPFLGIPDLSAPDPY------------------- 136
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30684018 271 pplgwydtvaYLVLPVLLIASQYVSMEIMkPPQTDDPAQKntlLVFKFLPLMIGYFALSVPSGLSIYWLVS 341
Cdd:COG0706 137 ----------YIFLPILMGVTMFLQQKLN-PAPAQDPQQK---KMMYIMPLMFLFFFLSFPAGLVLYWVVS 193
|
|
| 5TM_YidC_Alb3 |
cd20070 |
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ... |
141-341 |
9.49e-59 |
|
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410994 [Multi-domain] Cd Length: 181 Bit Score: 187.59 E-value: 9.49e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 141 GFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAGNQERIQLETSRLYKQAGVNPLAGCLPTLATIPVWI 220
Cdd:cd20070 1 GLAIILLTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYKDDKQKLQQEMMKLYKEHGVNPLGGCLPLLIQMPIFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 221 GLYQALSNVanEGLFTEGFFW-IPSLGGPTSiaarqsgsgiswlfpfvdghpplgwydtvaYLVLPVLLIASQYVSMEIM 299
Cdd:cd20070 81 ALYQVLRNS--IELRGAPFLWwILDLSAPDP------------------------------YYILPILMGVTMFLQQKLT 128
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 30684018 300 KPPQTDDPAQKNTLLvfKFLPLMIGYFALSVPSGLSIYWLVS 341
Cdd:cd20070 129 PTPTDDQAPQQKMMM--YFMPVMFTFIFLSFPSGLVLYWLVS 168
|
|
| yidC_oxa1_cterm |
TIGR03592 |
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ... |
140-341 |
3.31e-56 |
|
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274665 [Multi-domain] Cd Length: 179 Bit Score: 181.14 E-value: 3.31e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 140 YGFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAGNQERIQLETSRLYKQAGVNPLAGCLPTLATIPVW 219
Cdd:TIGR03592 2 WGLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYKEDPQKLQQEMMKLYKEEGVNPLGGCLPLLIQMPIF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 220 IGLYQALSNvaNEGLFTEGFFWIPSLGGPTsiaarqsgsgiswlfpfvdghpplgwydtvAYLVLPVLLIASQYVSMEIM 299
Cdd:TIGR03592 82 IALYQVLLR--SIELRHAPFLWIIDLSSPD------------------------------PYYILPILMGVTMFLQQKLS 129
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 30684018 300 KPPQTDDPAQKNTLlvfKFLPLMIGYFALSVPSGLSIYWLVS 341
Cdd:TIGR03592 130 PKGPPDPAQQKMMM---YFMPLMFLFFFLSFPAGLVLYWVVS 168
|
|
| PRK01318 |
PRK01318 |
membrane protein insertase; Provisional |
111-341 |
2.53e-46 |
|
membrane protein insertase; Provisional
Pssm-ID: 234942 [Multi-domain] Cd Length: 521 Bit Score: 164.66 E-value: 2.53e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 111 GWFGFISDAMELVLKILKDGLSAvhvpyaYGFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAGNQERI 190
Cdd:PRK01318 300 GWLWFITKPLFWLLDFLHSFVGN------WGWAIILLTIIVKLLLFPLTYKSYVSMAKMKVLQPKMQELKEKYKDDPQKM 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 191 QLETSRLYKQAGVNPLAGCLPTLATIPVWIGLYQALsnvaneglftegffwipslggPTSIAARQSgsgiswlfPFvdgh 270
Cdd:PRK01318 374 QQEMMELYKKEKVNPLGGCLPILIQIPIFFALYKVL---------------------LVSIELRHA--------PF---- 420
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 271 ppLGW------YDTV---AYLVLPVLLIASQYVSMeIMKPPQTdDPAQKNtllVFKFLPLMIGYFALSVPSGLSIYWLVS 341
Cdd:PRK01318 421 --IGWihdlsaPDPYfilHIGLLPILMGITMFLQQ-KLNPTPT-DPMQAK---IMKFMPLIFTFFFLSFPAGLVLYWIVN 493
|
|
| PRK00145 |
PRK00145 |
putative inner membrane protein translocase component YidC; Provisional |
113-341 |
1.27e-35 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234665 [Multi-domain] Cd Length: 223 Bit Score: 129.09 E-value: 1.27e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 113 FGFISDAMELVLKILKDGLSAV--HVPYAYGFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAGNQERI 190
Cdd:PRK00145 2 MRYLNNAFVQFFKFIHGFVSSVisNPNFSYGIAIILVTLIIRLLILPLNIKQTKSSLRMNEIQPEIKKLQAKYKNDPQKL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 191 QLETSRLYKQAGVNPLAGCLPTLATIPVWIGLYQALSNVanEGLFTEGFFWIPSLGGPTsiaarqsgsgISWlfpfvdgh 270
Cdd:PRK00145 82 QQEMMKLYKEKGVNPLGGCLPLLIQWPILIALYYVFNNL--TGINGVSFLWIKDLAKPD----------ITW-------- 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30684018 271 pplgwydtvaylVLPVLLIASQYVSMEIMKPPQTDDPAQKNTLLVfkFLPLMIGYFALSVPSGLSIYWLVS 341
Cdd:PRK00145 142 ------------ILPILSGATTYLSGYLMTKADSSQAGQMKTMNI--GMSIFMGVMSWKFKSALVLYWVIG 198
|
|
| PRK01315 |
PRK01315 |
putative inner membrane protein translocase component YidC; Provisional |
139-341 |
6.44e-31 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234941 Cd Length: 329 Bit Score: 119.46 E-value: 6.44e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 139 AYGFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAGNQERIQLETSRLYKQAGVNPLAGCLPTLATIPV 218
Cdd:PRK01315 41 TWVLSIVGLVIVIRALLIPLFVKQIKSQRNMQEIQPKMKKIQEKYKGDRERMSQEMMKLYKETGTNPLSSCLPLLLQMPI 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 219 WIGLYQALSNVANEGlftEGffwIPSLGGPTSIAARQS---GSGISWLFpFVDGHPPLGWYDTVAyLVLPVLLIASQYVS 295
Cdd:PRK01315 121 FFALYRVLDSAASRG---DG---IGPINPPLLESFRHAhifGAPLAATF-LQALNAGNTAVQVVA-AVLIILMSASQFIT 192
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 30684018 296 -MEIMK---PPQT-DDPAQKNTLLVFKFLPLMIGYFALSVPSGLSIYWLVS 341
Cdd:PRK01315 193 qLQLMTknmPPEAkTGPMAQQQKMLLYLFPLMFLVSGIAFPVGVLFYWLTS 243
|
|
| PRK01001 |
PRK01001 |
putative inner membrane protein translocase component YidC; Provisional |
111-347 |
2.71e-30 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234887 [Multi-domain] Cd Length: 795 Bit Score: 121.83 E-value: 2.71e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 111 GWFGFISDAMELVLKILKDGLSavHVPYAYGFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAGNQERI 190
Cdd:PRK01001 549 GFFSFITEPFAALLFIIMKFFK--FLTGSWGISIILLTVFLKLLLYPLNAWSIRSMRRMQKLSPYIQEIQQKYKKEPKRA 626
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 191 QLETSRLYKQAGVNPLAGCLPTLATIPVWIGLYQAL-SNVANEGL-FTEGffWIPSLGGPTSIaarqsgsgISWLFPFvd 268
Cdd:PRK01001 627 QMEIMALYKTNKVNPITGCLPLLIQLPFLIAMFDLLkSSFLLRGAsFIPG--WIDNLTAPDVL--------FSWETPI-- 694
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 269 ghpplgWYDTVAYLVLPVLL----IASQYVSMEIMKPPQTDDPAQKNTL-----LVFKFlplMIGYFalsvPSGLSIYWL 339
Cdd:PRK01001 695 ------WFIGNEFHLLPILLgvvmFAQQKISSLKRKGPVTDQQRQQEAMgtmmaLLFTF---MFYNF----PSGLNIYWL 761
|
....*...
gi 30684018 340 VSLSLKLL 347
Cdd:PRK01001 762 SSMLLGVI 769
|
|
| 5TM_YidC_Oxa1_Alb3 |
cd19751 |
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1 ... |
141-341 |
3.30e-28 |
|
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1/Alb3 protein family of insertases facilitate the insertion, folding and assembly of proteins of the inner membranes of bacteria and mitochondria, and the thylakoid membrane of plastids. Members include bacterial YidC, mitochondrial Cox18 and Oxa1, and chloroplastic Alb3 and Alb4. Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Oxa1 and Cox18/Oxa2 mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Alb3 and Alb3-like proteins, including Alb4, are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410992 [Multi-domain] Cd Length: 189 Bit Score: 108.41 E-value: 3.30e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 141 GFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRY------AGNQERIQLETSRLYKQAGVNPLAGCLPTLA 214
Cdd:cd19751 1 GLSIIIVTILIRLALLPLTLKQQKSMRKMQVIRPEMEAIREKYkekaskDKVQQEMQKEMLGLYKKHGVNPMAGCLPLFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 215 TIPVWIGLYQALSNVanEGLFTEGFFWIPSLGGPTSIaarqsgsgisWLFPFVDGhpplgwydtvaylvlpVLLIASQYV 294
Cdd:cd19751 81 QLPIFMAFYFAIMRT--EEIRYHTFLWFFDLGQPDYL----------YILPFVAG----------------ITTYFQFKM 132
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 30684018 295 SMEIMKPPQTDDPAQKNTLLVFkflPLMIGYFALSVPSGLSIYWLVS 341
Cdd:cd19751 133 TMSHQQQMQMMQMQMKVMLYVM---PVMIIIAGLSFPSALSLYWIIS 176
|
|
| PRK01622 |
PRK01622 |
membrane protein insertase YidC; |
133-341 |
4.89e-26 |
|
membrane protein insertase YidC;
Pssm-ID: 179310 Cd Length: 256 Bit Score: 104.45 E-value: 4.89e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 133 AVHVPYAYGFAIILLTIIVKAATYPLTKQQVESTLAMQN----LQPKIKAIQQRY-----AGNQERIQLETSRLYKQAGV 203
Cdd:PRK01622 53 AHHIGGSYGIAIIIVTLIIRSLMIPLAVSQYKSQRGMQEkmavMKPELDKIQAKLkvtkdLEKQKEYQKEMMELYKSGNI 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 204 NPLA-GCLPTLATIPVWIGLYQALSnvANEGLFTEGFFWipslggptsiaarqsgsgiswlfpFVDGHPPlgwydtvayL 282
Cdd:PRK01622 133 NPLAmGCLPLLIQMPILSAFYYAIR--RTEEIASHSFLW------------------------FNLGHAD---------H 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 30684018 283 VLPVLLIASQYVSMEIMKPPQTDDPAQKNTLLVFKFLPLMIGYFALSVPSGLSIYWLVS 341
Cdd:PRK01622 178 ILPIIAGLTYFIQMKVSQSNGTSPEQVQMLKIQGIMMPAMILFMSFAAPSALVLYWITG 236
|
|
| 5TM_Oxa1-like |
cd20069 |
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar ... |
143-341 |
5.70e-26 |
|
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar proteins; This group is composed mostly of the mitochondrial members of the YidC/Oxa1/Alb3 protein family of insertases, including mitochondrial inner membrane proteins Oxa1, Oxa1-like (Oxa1L), cytochrome c oxidase assembly protein 18 (Cox18, also called Oxa2), and Arabidopsis thaliana mitochondrial ALBINO3-like protein 3 (ALB33). It also includes Arabidopsis thaliana chloroplastic ALBINO3-like protein 2 (ALB32). Members of this group mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Oxa1 and Cox18/Oxa2 are essential for the activity and assembly of cytochrome c oxidase, playing central roles in the translocation and export of the N-terminal and C-terminal parts, respectively, of the COX2 protein into the mitochondrial intermembrane space. ALB32 may be involved in the insertion of integral membrane proteins into the chloroplast thylakoid membranes. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410993 [Multi-domain] Cd Length: 201 Bit Score: 102.60 E-value: 5.70e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 143 AIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQ-----RYAGNQE---RIQLETSRLYKQAGVNPLAGCLPTLA 214
Cdd:cd20069 7 TIAATTVALRLLLLPLVIKSQRNAARMANLQPELQKLQEklkeaRASGDQLeaaEARKELKELMKKHNVNPLKSLLLPLV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 215 TIPVWIGLYQALSNVAN---EGLFTEGFFWIPSLggptsiaarqsgsgiswlfpfvdghpplgwydTVA--YLVLPVLLI 289
Cdd:cd20069 87 QAPVFISFFFALRKMANlpvPSFKTGGLLWFTDL--------------------------------TVPdpYYILPILTS 134
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 30684018 290 ASQYVSMEI-MKPPQTDDPAQKNTLLVFKFLPLMIGYFALSVPSGLSIYWLVS 341
Cdd:cd20069 135 LTFLATIELgAETGTSGSPQSKTMKNVFRGLPVLMIPFTANFPSAVFLYWITS 187
|
|
| PRK02944 |
PRK02944 |
YidC family membrane integrase SpoIIIJ; |
140-340 |
4.21e-25 |
|
YidC family membrane integrase SpoIIIJ;
Pssm-ID: 179508 Cd Length: 255 Bit Score: 101.77 E-value: 4.21e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 140 YGFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRY----AGNQERIQLETSRLYKQAGVNPLAGCLPTLAT 215
Cdd:PRK02944 59 YGLAIIVVTLLIRLLILPLMIKQTKSTKAMQALQPEMQKLKEKYsskdQATQQKLQQEMMQLFQKNGVNPLAGCLPIFIQ 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 216 IPVWIGLYQALSNVANEGlfTEGFFWipslggptsiaarqsgsgiswlfpFVDGHPPlgwydtvAYLVLPVLLIASQYVS 295
Cdd:PRK02944 139 MPILIAFYHAIMRTSEIS--KHSFLW------------------------FDLGQAD-------PYYILPIVAGITTFIQ 185
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 30684018 296 MEI-MKPPQTDDPAQKNTLLVfkfLPLMIGYFALSVPSGLSIYWLV 340
Cdd:PRK02944 186 QKLmMAGTAGQNPQMAMMLWL---MPIMILIFAINFPAALSLYWVV 228
|
|
| PRK03449 |
PRK03449 |
putative inner membrane protein translocase component YidC; Provisional |
139-339 |
7.14e-25 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 179580 Cd Length: 304 Bit Score: 102.45 E-value: 7.14e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 139 AYGFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAGNQERIQLETSRLYKQAGVNPLAGCLPTLATIPV 218
Cdd:PRK03449 31 AWALSVMFLVFTLRALLYKPFVRQIRTTRKMQELQPQIKALQKKYGNDRQKMALEMQKLQKEHGFNPILGCLPMLAQIPV 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 219 WIGLYQAL-------SNVANEGLFTEGFFWIPSLG-GPTSIA----ARQSGSGIS-WLFPFVDGHPPLGWYDT--VAYLV 283
Cdd:PRK03449 111 FLGLFHVLrsfnrtgTGFGQLGMSVEENRNTPNYVfSAEDVQsfldARLFGAPLSaYITMPRSGLDAFVDFTRtnIILVG 190
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 30684018 284 LPVLLIAS------QYVSMEIMKPPQTDDP--AQKNTLLVFkFLPLMIGYFALSVPSGLSIYWL 339
Cdd:PRK03449 191 VPLMIIAGvathfnSRASVARQSAEAAANPqtAMMNKLALW-VFPLGVLVGGPFLPLAILLYWV 253
|
|
| PRK02654 |
PRK02654 |
putative inner membrane protein translocase component YidC; Provisional |
114-226 |
5.01e-19 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235058 Cd Length: 375 Bit Score: 86.96 E-value: 5.01e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 114 GFISDamELVLKILkD---GLsavhVPyAYGFAIILLTIIVKAATYPLTKQQVESTLAMQNLQP----KIKAIQQRYAGN 186
Cdd:PRK02654 6 GFISN--NVMLPIL-DffyGI----VP-SYGLAIVALTLVIRFALYPLSAGSIRNMRRMKIAQPvmqkRQAEIQERYKND 77
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 30684018 187 QERIQLETSRLYKQAGvNPLAGCLPTLATIPVWIGLYQAL 226
Cdd:PRK02654 78 PQKQQEEMGKLMKEFG-NPLAGCLPLLVQMPILFALFATL 116
|
|
| PRK00247 |
PRK00247 |
putative inner membrane protein translocase component YidC; Validated |
116-339 |
7.55e-19 |
|
putative inner membrane protein translocase component YidC; Validated
Pssm-ID: 178945 [Multi-domain] Cd Length: 429 Bit Score: 86.83 E-value: 7.55e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 116 ISDAMELVLKILKDGLSAVHVpYAYGFAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAGN------QER 189
Cdd:PRK00247 9 VSGVMKLWHLLLHNVLGLDDS-LAWFASLFGLVITVRAIIAPFTWQQYKSGRTAAHIRPKRKALREEYKGKtdeasiREL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 190 IQLEtSRLYKQAGVNPLAGCLPTLATIPVWIGLYQALSNVAN--EGLFTEGFfwiPSLGGPTS------IAARQSGSGIs 261
Cdd:PRK00247 88 QQKQ-KDLNKEYGYNPLAGCVPALIQIPVFLGLYQVLLRMARpeGGLENPVH---QPIGFLTSeevesfLQGRVFNVPL- 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 262 wlfPFVDGHPP-----LGW-YDTVAYLVLPVLLIASQY----VSMEIMKPPQTDDPAQKNTLLVFKFL----------PL 321
Cdd:PRK00247 163 ---PAYVSMPAeqlayLGTtQATVLAFVLPLFIAAAVFtainMAMSTYRSFQTNDHDSGFAVGMLKFLivmailapifPL 239
|
250
....*....|....*...
gi 30684018 322 MIGYFAlSVPSGLSIYWL 339
Cdd:PRK00247 240 SLGLTG-PFPTAIALYWV 256
|
|
| PRK02463 |
PRK02463 |
OxaA-like protein precursor; Provisional |
133-341 |
4.29e-13 |
|
OxaA-like protein precursor; Provisional
Pssm-ID: 235040 Cd Length: 307 Bit Score: 68.99 E-value: 4.29e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 133 AVHVPYAYGFAIILLTIIVKAATYPLTKQQV-ESTL---AMQNLQPKIKAIQQRY--AGNQER---IQLETSRLYKQAGV 203
Cdd:PRK02463 53 ANNLGLGFGLAIIIVTIIVRLIILPLGLYQSwKATYqseKMAYLKPVFEPINERLknATTQEEkmaAQTELMAAQRENGI 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 204 NPLA--GCLPTLATIPVWIGLYQALSNVanEGLFTEGFFWIPslggptsiaarqsgsgiswlfpfvdghppLGWYDTVAY 281
Cdd:PRK02463 133 SMLGgiGCLPLLIQMPFFSALYFAAQYT--KGVSTSTFLGID-----------------------------LGSPSLVLT 181
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 282 LVLPVLLIASQYVSMEIMKPPQTDdpAQKNTLLVfkfLPLMIGYFALSVPSGLSIYWLVS 341
Cdd:PRK02463 182 AIIGVLYFFQSWLSMMGVPEEQRE--QMKAMMYM---MPIMMVVFSFSSPAGVGLYWLVG 236
|
|
| PRK02201 |
PRK02201 |
putative inner membrane protein translocase component YidC; Provisional |
142-341 |
5.06e-11 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235012 Cd Length: 357 Bit Score: 63.11 E-value: 5.06e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 142 FAIILLTIIVKAATYPLTKQQVESTLAMQNLQPKIKAIQQRYAG------NQERIQLETSRLYKQAGVNPLAGCLPTLAT 215
Cdd:PRK02201 135 LAIIVVVLIIRLISFLITFKSTFNQEKQEELQGKKAKIDAKYKDykkdkqMKQRKQQEIQELYKKHNISPFSPFVQMFVT 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30684018 216 IPVWIGLYQALSNvaneglftegffwIPSLGGPTSIAARQSGSGISWLFpfvdghpPLGWydtvAYLVLPVLLIASQYVS 295
Cdd:PRK02201 215 LPIFIAVYRVVQS-------------LPSIKVTTWLGIDLSATSWQEIF-------AGNW----IYLPILIIVVPVQALS 270
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 30684018 296 MEImkpPQ----------TDDPAQKNTL-----------LVFKFlplmigyFALSVPSGLSIYWLVS 341
Cdd:PRK02201 271 QLL---PQilnkkknkerTLNVKEKEALkkqnktqniisIVFIF-------FGVIFAAGVQIYWIIG 327
|
|
|