|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05218 |
PRK05218 |
heat shock protein 90; Provisional |
77-735 |
0e+00 |
|
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain] Cd Length: 613 Bit Score: 750.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 77 EKFEYQAEVSRLLDLIVHSLYSHKEVFLRELVSNASDALDKLRFLSVTEPSLLGDGGDLEIRIKPDPDNGTITITDTGIG 156
Cdd:PRK05218 4 ETGEFQAEVKQLLHLMIHSLYSNKEIFLRELISNASDAIDKLRFEALTDPALYEGDGDLKIRISFDKEARTLTISDNGIG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 157 MTKEELIDCLGTIAQSGTSKFLKALKENKDlgADNGLIGQFGVGFYSAFLVAEKVVVSTKSPKSDKQ-YVWESvADSSSY 235
Cdd:PRK05218 84 MTREEVIENLGTIAKSGTKEFLEKLKGDQK--KDSQLIGQFGVGFYSAFMVADKVTVITRSAGPAAEaVRWES-DGEGEY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 236 LIREETDPDnilrRGTQITLYLREDDKyEFAESTRIKNLVKNYSQFVGFPIYtwqeksrtIEVEEDEPVkegeegepkkk 315
Cdd:PRK05218 161 TIEEIEKEE----RGTEITLHLKEDED-EFLDEWRIRSIIKKYSDFIPVPIK--------LEKEEEETI----------- 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 316 kttktekywdwelaNETKPLWMRNSKEVEKGEYNEFYKKAFNEFLDPLAHTHFTTEGEVEFRSILYIPGMGPlnnEDVTN 395
Cdd:PRK05218 217 --------------NSASALWTRSKSEITDEEYKEFYKHLAHDFDDPLFWIHNNVEGPFEYTGLLYIPKKAP---FDLFN 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 396 PKTKN-IRLYVKRVFISDDFDgELFPRYLSFVKGVVDSDDLPLNVSREILQESRIVRIMRKRLIRKTFDMIQEISESENK 474
Cdd:PRK05218 280 RDRKGgLKLYVKRVFIMDDAE-ELLPEYLRFVKGVIDSEDLPLNVSREILQEDRVVKKIRKAITKKVLDELEKLAKNDRE 358
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 475 --EKFWENFGRFLKLGCIEDTGNHKRITPLLRFFSSKnEEELTSLDDYIENMGENQKAIYYLATDSLKSAKSAPFLEKLI 552
Cdd:PRK05218 359 kyEKFWKEFGPVLKEGLYEDFANREKLAKLLRFASTH-EGKYVSLAEYVERMKEGQKKIYYITGDSREAAKNSPHLELFK 437
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 553 QKDIEVLYLVEPIDEVAIQNLQTYKEKKFVDISKEDLELGDEDEV---KDREAKQEFNLLCDWIKQQLGDKVAKVQVSNR 629
Cdd:PRK05218 438 KKGIEVLLLTDPIDEFWISYLEEFDGKPFKSVARGDLDLGKEDEEekeEKEEAEEEFKPLLERLKEALGDKVKDVRLSHR 517
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 630 LSSSPCVLVSGKFGWSANMERLMKAQalgdtsSLEFMRGRRILEINPDHPIIKDLnaacKNAPESTEATRVVDLLYDTAI 709
Cdd:PRK05218 518 LTDSPACLVADEGDMSTQMEKLLKAA------GQEVPESKPILEINPNHPLVKKL----ADEADEAKFKDLAELLYDQAL 587
|
650 660
....*....|....*....|....*.
gi 30678090 710 ISSGFTPDSPAELGNKIYEMMAMAVG 735
Cdd:PRK05218 588 LAEGGSLEDPAAFVKRLNELLLKLLA 613
|
|
| HtpG |
COG0326 |
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ... |
77-735 |
0e+00 |
|
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain] Cd Length: 616 Bit Score: 748.49 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 77 EKFEYQAEVSRLLDLIVHSLYSHKEVFLRELVSNASDALDKLRFLSVTEPSLLGDGGDLEIRIKPDPDNGTITITDTGIG 156
Cdd:COG0326 4 ETGEFQAEVKQLLDLMIHSLYSNKEIFLRELISNASDAIDKLRFLALTDPELKEEDGDLKIRIEVDKEAKTLTISDNGIG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 157 MTKEELIDCLGTIAQSGTSKFLKALKEnkDLGADNGLIGQFGVGFYSAFLVAEKVVVSTKSPKSDKQ-YVWESVADsSSY 235
Cdd:COG0326 84 MTREEVIENLGTIAKSGTREFLEKLKG--DQKKDSDLIGQFGVGFYSAFMVADKVEVVTRSAGEDAEaVRWESDGD-GEY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 236 LIREETDPDnilrRGTQITLYLREDDKyEFAESTRIKNLVKNYSQFVGFPIYTWQEKSRTIEveedepvkegeegepkkk 315
Cdd:COG0326 161 TIEEAEKAE----RGTEITLHLKEDAE-EFLEEWRLREIIKKYSDFIPVPIKMEGEEEETEE------------------ 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 316 kttktekywdWELANETKPLWMRNSKEVEKGEYNEFYKKAFNEFLDPLAHTHFTTEGEVEFRSILYIPGMGPlnnEDVTN 395
Cdd:COG0326 218 ----------DETINSATALWTRSKSEITDEEYKEFYKHLFHDFEDPLFWIHLNVEGPFEYTGLLYIPKKAP---FDLYD 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 396 PKTKN-IRLYVKRVFISDDFDgELFPRYLSFVKGVVDSDDLPLNVSREILQESRIVRIMRKRLIRKTFDMIQEISESENK 474
Cdd:COG0326 285 RDRKGgIKLYVKRVFIMDDAE-DLLPEYLRFVRGVVDSPDLPLNVSREILQEDRQLKKIRKAITKKVLDELEKLAKNDRE 363
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 475 --EKFWENFGRFLKLGCIEDTGNHKRITPLLRFFSSKnEEELTSLDDYIENMGENQKAIYYLATDSLKSAKSAPFLEKLI 552
Cdd:COG0326 364 kyEKFWKEFGLVLKEGALEDFKNREKIADLLRFESTK-EGGYVTLAEYVERMKEGQKKIYYITGESREAAEQSPHLEIFK 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 553 QKDIEVLYLVEPIDEVAIQNLQTYKEKKFVDISKEDLELGDEDEVKDRE-AKQEFNLLCDWIKQQLGDKVAKVQVSNRLS 631
Cdd:COG0326 443 AKGIEVLLLTDPIDEFLISHLEEFDGKKFKSVDSGDLDLDKLEEKKESEeEEEEFKPLLERFKEALGDKVKDVRVSARLT 522
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 632 SSPCVLVSGKFGWSANMERLMKAQalGDtsslEFMRGRRILEINPDHPIIKDLnaacKNAPESTEATRVVDLLYDTAIIS 711
Cdd:COG0326 523 DSPACLVADEGDMSRRMEKMLKAM--GQ----DMPEAKPILEINPNHPLVKKL----AAEEDEELFKDLAELLYDQALLA 592
|
650 660
....*....|....*....|....
gi 30678090 712 SGFTPDSPAELGNKIYEMMAMAVG 735
Cdd:COG0326 593 EGGLLEDPAAFVKRLNKLLEKALG 616
|
|
| HSP90 |
pfam00183 |
Hsp90 protein; |
264-762 |
0e+00 |
|
Hsp90 protein;
Pssm-ID: 459703 Cd Length: 516 Bit Score: 689.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 264 EFAESTRIKNLVKNYSQFVGFPIYTWQEKSRTIEVEEDEPVKEGEEGEPKKKKTTK---------------TEKYWDWEL 328
Cdd:pfam00183 1 EYLEEKKIKELVKKYSEFINFPIYLWVEKEEEVEVPDEEEEEEEEEEEEEDDDPKVeeedeeeekkktkkvKETVWEWEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 329 ANETKPLWMRNSKEVEKGEYNEFYKKAFNEFLDPLAHTHFTTEGEVEFRSILYIPGMGPLNNEDvTNPKTKNIRLYVKRV 408
Cdd:pfam00183 81 LNKTKPIWTRNPKEVTEEEYAEFYKSLSKDWEDPLAVKHFSVEGEVEFKSLLFIPKRAPFDLFE-NKKKKNNIKLYVRRV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 409 FISDDFDgELFPRYLSFVKGVVDSDDLPLNVSREILQESRIVRIMRKRLIRKTFDMIQEISESENK-EKFWENFGRFLKL 487
Cdd:pfam00183 160 FITDDFE-DLIPEYLNFVKGVVDSDDLPLNVSRETLQQNKILKVIKKKLVRKALDMFKEIAEEKEDyKKFWKEFGKNLKL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 488 GCIEDTGNHKRITPLLRFFSSKNEEELTSLDDYIENMGENQKAIYYLATDSLKSAKSAPFLEKLIQKDIEVLYLVEPIDE 567
Cdd:pfam00183 239 GIIEDSSNRNKLAKLLRFYSSKSGDELTSLDDYVSRMKEGQKHIYYITGESKEEVENSPFLERLKKKGYEVLYLTDPIDE 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 568 VAIQNLQTYKEKKFVDISKEDLEL--GDEDEVKDREAKQEFNLLCDWIKQQLGDKVAKVQVSNRLSSSPCVLVSGKFGWS 645
Cdd:pfam00183 319 YAVQQLKEFDGKKLVNVAKEGLELeeDEEEKKKDEELKKEFEPLTKWLKDVLGDKVEKVVVSNRLVDSPCVLVTSQYGWS 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 646 ANMERLMKAQALG-DTSSLEFMRGRRILEINPDHPIIKDLNAACKNAPESTEATRVVDLLYDTAIISSGFTPDSPAELGN 724
Cdd:pfam00183 399 ANMERIMKAQALRkDSSMSSYMSSKKTLEINPRHPIIKELLKRVEADKDDKTAKDLALLLYETALLRSGFSLEDPASFAS 478
|
490 500 510
....*....|....*....|....*....|....*...
gi 30678090 725 KIYEMMAMAVGGRWGRVEEEEESSTVNEGDDKSGETEV 762
Cdd:pfam00183 479 RIYRMLKLGLGIDEDEIVEEEDEIEEEEEEEEEEPEEE 516
|
|
| HATPase_Hsp90-like |
cd16927 |
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ... |
86-282 |
1.11e-101 |
|
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain] Cd Length: 189 Bit Score: 310.99 E-value: 1.11e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 86 SRLLDLIVHSLYSHKEVFLRELVSNASDALDKLRFLSVTEPSLLGDGGDLEIRIKPDPDNGTITITDTGIGMTKEELIDC 165
Cdd:cd16927 1 NQLLDLIIHSLYSNKEIFLRELISNASDALDKLRYLSLTDPSLLDDDPELEIRISPDKENRTLTISDTGIGMTKEELINN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 166 LGTIAQSGTSKFLKALKENKDlgaDNGLIGQFGVGFYSAFLVAEKVVVSTKSPKSDKQYVWESVADSSSYLireeTDPDN 245
Cdd:cd16927 81 LGTIARSGTKAFLEALQEGAK---DSDLIGQFGVGFYSAFMVADKVTVTTKSAGDDEGYRWESDGGGSYTI----EEAEG 153
|
170 180 190
....*....|....*....|....*....|....*..
gi 30678090 246 ILRRGTQITLYLREDDkYEFAESTRIKNLVKNYSQFV 282
Cdd:cd16927 154 ELGRGTKITLHLKEDA-KEFLEEARIKELVKKYSDFI 189
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
101-211 |
1.97e-09 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 55.73 E-value: 1.97e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 101 EVFLRELVSNASDALDKLRFlsvtepsllgDGGDLEIRIKPDPDNGTITITDTGIGMTKEELidclgtiaqsgtskfLKA 180
Cdd:smart00387 3 PDRLRQVLSNLLDNAIKYTP----------EGGRITVTLERDGDHVEITVEDNGPGIPPEDL---------------EKI 57
|
90 100 110
....*....|....*....|....*....|.
gi 30678090 181 LKENKDLGADNGLIGQFGVGFYSAFLVAEKV 211
Cdd:smart00387 58 FEPFFRTDKRSRKIGGTGLGLSIVKKLVELH 88
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05218 |
PRK05218 |
heat shock protein 90; Provisional |
77-735 |
0e+00 |
|
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain] Cd Length: 613 Bit Score: 750.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 77 EKFEYQAEVSRLLDLIVHSLYSHKEVFLRELVSNASDALDKLRFLSVTEPSLLGDGGDLEIRIKPDPDNGTITITDTGIG 156
Cdd:PRK05218 4 ETGEFQAEVKQLLHLMIHSLYSNKEIFLRELISNASDAIDKLRFEALTDPALYEGDGDLKIRISFDKEARTLTISDNGIG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 157 MTKEELIDCLGTIAQSGTSKFLKALKENKDlgADNGLIGQFGVGFYSAFLVAEKVVVSTKSPKSDKQ-YVWESvADSSSY 235
Cdd:PRK05218 84 MTREEVIENLGTIAKSGTKEFLEKLKGDQK--KDSQLIGQFGVGFYSAFMVADKVTVITRSAGPAAEaVRWES-DGEGEY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 236 LIREETDPDnilrRGTQITLYLREDDKyEFAESTRIKNLVKNYSQFVGFPIYtwqeksrtIEVEEDEPVkegeegepkkk 315
Cdd:PRK05218 161 TIEEIEKEE----RGTEITLHLKEDED-EFLDEWRIRSIIKKYSDFIPVPIK--------LEKEEEETI----------- 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 316 kttktekywdwelaNETKPLWMRNSKEVEKGEYNEFYKKAFNEFLDPLAHTHFTTEGEVEFRSILYIPGMGPlnnEDVTN 395
Cdd:PRK05218 217 --------------NSASALWTRSKSEITDEEYKEFYKHLAHDFDDPLFWIHNNVEGPFEYTGLLYIPKKAP---FDLFN 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 396 PKTKN-IRLYVKRVFISDDFDgELFPRYLSFVKGVVDSDDLPLNVSREILQESRIVRIMRKRLIRKTFDMIQEISESENK 474
Cdd:PRK05218 280 RDRKGgLKLYVKRVFIMDDAE-ELLPEYLRFVKGVIDSEDLPLNVSREILQEDRVVKKIRKAITKKVLDELEKLAKNDRE 358
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 475 --EKFWENFGRFLKLGCIEDTGNHKRITPLLRFFSSKnEEELTSLDDYIENMGENQKAIYYLATDSLKSAKSAPFLEKLI 552
Cdd:PRK05218 359 kyEKFWKEFGPVLKEGLYEDFANREKLAKLLRFASTH-EGKYVSLAEYVERMKEGQKKIYYITGDSREAAKNSPHLELFK 437
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 553 QKDIEVLYLVEPIDEVAIQNLQTYKEKKFVDISKEDLELGDEDEV---KDREAKQEFNLLCDWIKQQLGDKVAKVQVSNR 629
Cdd:PRK05218 438 KKGIEVLLLTDPIDEFWISYLEEFDGKPFKSVARGDLDLGKEDEEekeEKEEAEEEFKPLLERLKEALGDKVKDVRLSHR 517
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 630 LSSSPCVLVSGKFGWSANMERLMKAQalgdtsSLEFMRGRRILEINPDHPIIKDLnaacKNAPESTEATRVVDLLYDTAI 709
Cdd:PRK05218 518 LTDSPACLVADEGDMSTQMEKLLKAA------GQEVPESKPILEINPNHPLVKKL----ADEADEAKFKDLAELLYDQAL 587
|
650 660
....*....|....*....|....*.
gi 30678090 710 ISSGFTPDSPAELGNKIYEMMAMAVG 735
Cdd:PRK05218 588 LAEGGSLEDPAAFVKRLNELLLKLLA 613
|
|
| HtpG |
COG0326 |
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ... |
77-735 |
0e+00 |
|
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain] Cd Length: 616 Bit Score: 748.49 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 77 EKFEYQAEVSRLLDLIVHSLYSHKEVFLRELVSNASDALDKLRFLSVTEPSLLGDGGDLEIRIKPDPDNGTITITDTGIG 156
Cdd:COG0326 4 ETGEFQAEVKQLLDLMIHSLYSNKEIFLRELISNASDAIDKLRFLALTDPELKEEDGDLKIRIEVDKEAKTLTISDNGIG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 157 MTKEELIDCLGTIAQSGTSKFLKALKEnkDLGADNGLIGQFGVGFYSAFLVAEKVVVSTKSPKSDKQ-YVWESVADsSSY 235
Cdd:COG0326 84 MTREEVIENLGTIAKSGTREFLEKLKG--DQKKDSDLIGQFGVGFYSAFMVADKVEVVTRSAGEDAEaVRWESDGD-GEY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 236 LIREETDPDnilrRGTQITLYLREDDKyEFAESTRIKNLVKNYSQFVGFPIYTWQEKSRTIEveedepvkegeegepkkk 315
Cdd:COG0326 161 TIEEAEKAE----RGTEITLHLKEDAE-EFLEEWRLREIIKKYSDFIPVPIKMEGEEEETEE------------------ 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 316 kttktekywdWELANETKPLWMRNSKEVEKGEYNEFYKKAFNEFLDPLAHTHFTTEGEVEFRSILYIPGMGPlnnEDVTN 395
Cdd:COG0326 218 ----------DETINSATALWTRSKSEITDEEYKEFYKHLFHDFEDPLFWIHLNVEGPFEYTGLLYIPKKAP---FDLYD 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 396 PKTKN-IRLYVKRVFISDDFDgELFPRYLSFVKGVVDSDDLPLNVSREILQESRIVRIMRKRLIRKTFDMIQEISESENK 474
Cdd:COG0326 285 RDRKGgIKLYVKRVFIMDDAE-DLLPEYLRFVRGVVDSPDLPLNVSREILQEDRQLKKIRKAITKKVLDELEKLAKNDRE 363
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 475 --EKFWENFGRFLKLGCIEDTGNHKRITPLLRFFSSKnEEELTSLDDYIENMGENQKAIYYLATDSLKSAKSAPFLEKLI 552
Cdd:COG0326 364 kyEKFWKEFGLVLKEGALEDFKNREKIADLLRFESTK-EGGYVTLAEYVERMKEGQKKIYYITGESREAAEQSPHLEIFK 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 553 QKDIEVLYLVEPIDEVAIQNLQTYKEKKFVDISKEDLELGDEDEVKDRE-AKQEFNLLCDWIKQQLGDKVAKVQVSNRLS 631
Cdd:COG0326 443 AKGIEVLLLTDPIDEFLISHLEEFDGKKFKSVDSGDLDLDKLEEKKESEeEEEEFKPLLERFKEALGDKVKDVRVSARLT 522
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 632 SSPCVLVSGKFGWSANMERLMKAQalGDtsslEFMRGRRILEINPDHPIIKDLnaacKNAPESTEATRVVDLLYDTAIIS 711
Cdd:COG0326 523 DSPACLVADEGDMSRRMEKMLKAM--GQ----DMPEAKPILEINPNHPLVKKL----AAEEDEELFKDLAELLYDQALLA 592
|
650 660
....*....|....*....|....
gi 30678090 712 SGFTPDSPAELGNKIYEMMAMAVG 735
Cdd:COG0326 593 EGGLLEDPAAFVKRLNKLLEKALG 616
|
|
| HSP90 |
pfam00183 |
Hsp90 protein; |
264-762 |
0e+00 |
|
Hsp90 protein;
Pssm-ID: 459703 Cd Length: 516 Bit Score: 689.68 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 264 EFAESTRIKNLVKNYSQFVGFPIYTWQEKSRTIEVEEDEPVKEGEEGEPKKKKTTK---------------TEKYWDWEL 328
Cdd:pfam00183 1 EYLEEKKIKELVKKYSEFINFPIYLWVEKEEEVEVPDEEEEEEEEEEEEEDDDPKVeeedeeeekkktkkvKETVWEWEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 329 ANETKPLWMRNSKEVEKGEYNEFYKKAFNEFLDPLAHTHFTTEGEVEFRSILYIPGMGPLNNEDvTNPKTKNIRLYVKRV 408
Cdd:pfam00183 81 LNKTKPIWTRNPKEVTEEEYAEFYKSLSKDWEDPLAVKHFSVEGEVEFKSLLFIPKRAPFDLFE-NKKKKNNIKLYVRRV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 409 FISDDFDgELFPRYLSFVKGVVDSDDLPLNVSREILQESRIVRIMRKRLIRKTFDMIQEISESENK-EKFWENFGRFLKL 487
Cdd:pfam00183 160 FITDDFE-DLIPEYLNFVKGVVDSDDLPLNVSRETLQQNKILKVIKKKLVRKALDMFKEIAEEKEDyKKFWKEFGKNLKL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 488 GCIEDTGNHKRITPLLRFFSSKNEEELTSLDDYIENMGENQKAIYYLATDSLKSAKSAPFLEKLIQKDIEVLYLVEPIDE 567
Cdd:pfam00183 239 GIIEDSSNRNKLAKLLRFYSSKSGDELTSLDDYVSRMKEGQKHIYYITGESKEEVENSPFLERLKKKGYEVLYLTDPIDE 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 568 VAIQNLQTYKEKKFVDISKEDLEL--GDEDEVKDREAKQEFNLLCDWIKQQLGDKVAKVQVSNRLSSSPCVLVSGKFGWS 645
Cdd:pfam00183 319 YAVQQLKEFDGKKLVNVAKEGLELeeDEEEKKKDEELKKEFEPLTKWLKDVLGDKVEKVVVSNRLVDSPCVLVTSQYGWS 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 646 ANMERLMKAQALG-DTSSLEFMRGRRILEINPDHPIIKDLNAACKNAPESTEATRVVDLLYDTAIISSGFTPDSPAELGN 724
Cdd:pfam00183 399 ANMERIMKAQALRkDSSMSSYMSSKKTLEINPRHPIIKELLKRVEADKDDKTAKDLALLLYETALLRSGFSLEDPASFAS 478
|
490 500 510
....*....|....*....|....*....|....*...
gi 30678090 725 KIYEMMAMAVGGRWGRVEEEEESSTVNEGDDKSGETEV 762
Cdd:pfam00183 479 RIYRMLKLGLGIDEDEIVEEEDEIEEEEEEEEEEPEEE 516
|
|
| PTZ00272 |
PTZ00272 |
heat shock protein 83 kDa (Hsp83); Provisional |
77-770 |
0e+00 |
|
heat shock protein 83 kDa (Hsp83); Provisional
Pssm-ID: 240341 Cd Length: 701 Bit Score: 622.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 77 EKFEYQAEVSRLLDLIVHSLYSHKEVFLRELVSNASDALDKLRFLSVTEPSLLGDGGDLEIRIKPDPDNGTITITDTGIG 156
Cdd:PTZ00272 3 ETFAFQAEINQLMSLIINTFYSNKEIFLRELISNASDACDKIRYQSLTDPSVLGESPRLCIRVVPDKENKTLTVEDNGIG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 157 MTKEELIDCLGTIAQSGTSKFLKALkenkDLGADNGLIGQFGVGFYSAFLVAEKVVVSTKSpKSDKQYVWESVADSSSYL 236
Cdd:PTZ00272 83 MTKADLVNNLGTIARSGTKAFMEAL----EAGGDMSMIGQFGVGFYSAYLVADRVTVTSKN-NSDESYVWESSAGGTFTI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 237 IreeTDPDNILRRGTQITLYLREDDKyEFAESTRIKNLVKNYSQFVGFPIYTWQEKSRTIEV----EED----------- 301
Cdd:PTZ00272 158 T---STPESDMKRGTRITLHLKEDQM-EYLEPRRLKELIKKHSEFIGYDIELMVEKTTEKEVtdedEEDtkkadedgeep 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 302 --EPVKEGEEGEPKKKKTTKTEKYwDWELANETKPLWMRNSKEVEKGEYNEFYKKAFNEFLDPLAHTHFTTEGEVEFRSI 379
Cdd:PTZ00272 234 kvEEVKEGDEGKKKKTKKVKEVTK-EYEVQNKHKPLWTRDPKDVTKEEYAAFYKAISNDWEDPAATKHFSVEGQLEFRSI 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 380 LYIPGMGPLNNEDvTNPKTKNIRLYVKRVFISDDFDgELFPRYLSFVKGVVDSDDLPLNVSREILQESRIVRIMRKRLIR 459
Cdd:PTZ00272 313 MFVPKRAPFDMFE-PNKKRNNIKLYVRRVFIMDNCE-DLCPDWLGFVKGVVDSEDLPLNISRENLQQNKILKVIRKNIVK 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 460 KTFDMIQEISES-ENKEKFWENFGRFLKLGCIEDTGNHKRITPLLRFFSSKNEEELTSLDDYIENMGENQKAIYYLATDS 538
Cdd:PTZ00272 391 KCLEMFDEVAENkEDYKQFYEQFGKNIKLGIHEDTANRKKLMELLRFYSTESGEEMTTLKDYVTRMKAGQKSIYYITGDS 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 539 LKSAKSAPFLEKLIQKDIEVLYLVEPIDEVAIQNLQTYKEKKFVDISKEDLELGD-EDEVKDR-EAKQEFNLLCDWIKQQ 616
Cdd:PTZ00272 471 KKKLETSPFIEQARRRGLEVLFMTEPIDEYVMQQVKDFEDKKFACLTKEGVHFEEsEEEKQQReEEKAACEKLCKTMKEV 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 617 LGDKVAKVQVSNRLSSSPCVLVSGKFGWSANMERLMKAQALGDTSSLEFMRGRRILEINPDHPIIKDLNAACKnAPESTE 696
Cdd:PTZ00272 551 LGDKVEKVIVSERLSTSPCILVTSEFGWSAHMEQIMRNQALRDSSMAQYMMSKKTMELNPRHPIIKELRRRVG-ADENDK 629
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 30678090 697 ATR-VVDLLYDTAIISSGFTPDSPAELGNKIYEMMAMAVggrwgrveeeeessTVNEGDDKSGETEVVE--PSEVRA 770
Cdd:PTZ00272 630 AVKdLVFLLFDTSLLTSGFQLEDPTGYAERINRMIKLGL--------------SLDEEEEEAAEAPVAEtaPAEVTA 692
|
|
| PTZ00130 |
PTZ00130 |
heat shock protein 90; Provisional |
65-735 |
5.51e-178 |
|
heat shock protein 90; Provisional
Pssm-ID: 185466 [Multi-domain] Cd Length: 814 Bit Score: 530.77 E-value: 5.51e-178
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 65 VAEKETTEEGSgEKFEYQAEVSRLLDLIVHSLYSHKEVFLRELVSNASDALDKLRFLSVTEPSLLGDGGDLEIRIKPDPD 144
Cdd:PTZ00130 55 IEDGEKPTSGI-EQHQYQTEVTRLMDIIVNSLYTQKEVFLRELISNAADALEKIRFLSLSDESVLGEEKKLEIRISANKE 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 145 NGTITITDTGIGMTKEELIDCLGTIAQSGTSKFLKALKENkdlGADNGLIGQFGVGFYSAFLVAEKVVVSTKSpKSDKQY 224
Cdd:PTZ00130 134 KNILSITDTGIGMTKEDLINNLGTIAKSGTSNFLEAISKS---GGDMSLIGQFGVGFYSAFLVADKVIVYTKN-NNDEQY 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 225 VWESVADSSSYLIReetDP-DNILRRGTQITLYLReDDKYEFAESTRIKNLVKNYSQFVGFPIYTWQEKSRTIEVEED-- 301
Cdd:PTZ00130 210 IWESTADAKFTIYK---DPrGSTLKRGTRISLHLK-EDATNLMNDKKLVDLISKYSQFIQYPIYLLHENVYTEEVLADia 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 302 ---------EPVKEGEEGEPKKKKTTKTEKYWDWELANETKPLWMRNSKEVEKGEYNEFYK--KAFNEflDPLAHTHFTT 370
Cdd:PTZ00130 286 kemendpnyDSVKVEETDDPNKKTRTVEKKVKKWKLMNEQKPIWLRPPKELTDEDYKKFFSvlSGFND--EPLYHIHFFA 363
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 371 EGEVEFRSILYIPGMGPLNNEDVTNpKTKNIRLYVKRVFISDDFDgELFPRYLSFVKGVVDSDDLPLNVSREILQESRIV 450
Cdd:PTZ00130 364 EGEIEFKCLIYIPSRAPSINDHLFT-KQNSIKLYVRRVLVADEFV-EFLPRYMSFVKGVVDSDDLPLNVSREQLQQNKIL 441
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 451 RIMRKRLIRKTFDMIQEISESENKEK-------------------------------FWENFGRFLKLGCIEDTGNHKRI 499
Cdd:PTZ00130 442 KAVSKRIVRKILDTFRTLYKEGKKNKetlraelaketdeekkkeiqkkinepstyklIYKEYRKYLKTGCYEDDINRNKI 521
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 500 TPLLRFFSSKNEEELtSLDDYIENMGENQKAIYYLATDSLKSAKSAPFLEKLIQKDIEVLYLVEPIDEVAIQNLQTYKEK 579
Cdd:PTZ00130 522 VKLLLFKTMLHPKSI-SLDTYIENMKPDQKFIYYASGDSYEYLSKIPQLQIFKKKNIDVVFLTESVDESCVQRVQEYDGK 600
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 580 KFVDISKEDL--ELGDEDEVKDREAKQEFNLLCDWIKQQLGDKVAKVQVSNRLSSSPCVLVSGKFGWSANMERLMKAQaL 657
Cdd:PTZ00130 601 KFKSIQKGEItfELTEDEKKKEEKVKKMYKALIDVISDTLRNQIFKVEISRRLVDAPCAVVSTEWGLSGQMEKLMKIN-V 679
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 30678090 658 GDTSSLEFMRGRRILEINPDHPIIKDLNAACKNAPESTEATRVVDLLYDTAIISSGFTPDSPAELGNKIYEMMAMAVG 735
Cdd:PTZ00130 680 NNSDQIKAMSGQKILEINPDHPIMIDLLKRSVSNPKDSQLTESIKIIYQSAKLASGFDLEDTADLAQIVYDHINQKLG 757
|
|
| HATPase_Hsp90-like |
cd16927 |
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ... |
86-282 |
1.11e-101 |
|
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain] Cd Length: 189 Bit Score: 310.99 E-value: 1.11e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 86 SRLLDLIVHSLYSHKEVFLRELVSNASDALDKLRFLSVTEPSLLGDGGDLEIRIKPDPDNGTITITDTGIGMTKEELIDC 165
Cdd:cd16927 1 NQLLDLIIHSLYSNKEIFLRELISNASDALDKLRYLSLTDPSLLDDDPELEIRISPDKENRTLTISDTGIGMTKEELINN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 166 LGTIAQSGTSKFLKALKENKDlgaDNGLIGQFGVGFYSAFLVAEKVVVSTKSPKSDKQYVWESVADSSSYLireeTDPDN 245
Cdd:cd16927 81 LGTIARSGTKAFLEALQEGAK---DSDLIGQFGVGFYSAFMVADKVTVTTKSAGDDEGYRWESDGGGSYTI----EEAEG 153
|
170 180 190
....*....|....*....|....*....|....*..
gi 30678090 246 ILRRGTQITLYLREDDkYEFAESTRIKNLVKNYSQFV 282
Cdd:cd16927 154 ELGRGTKITLHLKEDA-KEFLEEARIKELVKKYSDFI 189
|
|
| PRK14083 |
PRK14083 |
HSP90 family protein; Provisional |
81-536 |
1.38e-39 |
|
HSP90 family protein; Provisional
Pssm-ID: 237603 [Multi-domain] Cd Length: 601 Bit Score: 155.10 E-value: 1.38e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 81 YQAEVSRLLDLIVHSLYSHKEVFLRELVSNASDALDKLRFLsvtEPSLLGdggdlEIRIKP-DPDNGTITITDTGIGMTK 159
Cdd:PRK14083 5 FQVDLRGVIDLLSRHLYSSPRVYVRELLQNAVDAITARRAL---DPTAPG-----RIRIELtDAGGGTLIVEDNGIGLTE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 160 EELIDCLGTIAQSGtskflkalKENKDLGAD-NGLIGQFGVGFYSAFLVAEKVVVSTKSPKSDKQYVWESVADSSsYLIR 238
Cdd:PRK14083 77 EEVHEFLATIGRSS--------KRDENLGFArNDFLGQFGIGLLSCFLVADEIVVVSRSAKDGPAVEWRGKADGT-YSVR 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 239 E-ETDPDNIlrrGTQITLYLREDDKyEFAESTRIKNLVKNYSQFVGFPIYtwqeksrtieVEEDEPvkegeegepkkkkt 317
Cdd:PRK14083 148 KlETERAEP---GTTVYLRPRPDAE-EWLERETVEELAKKYGSLLPVPIR----------VEGEKG-------------- 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 318 tktekywdweLANETKPLWMRN--SKEVEKGEYNEFYKKAF-NEFLD--PLAHTHFTTEGevefrsILYIPGMGPlnned 392
Cdd:PRK14083 200 ----------GVNETPPPWTRDypDPETRREALLAYGEELLgFTPLDviPLDVPSGGLEG------VAYVLPYAV----- 258
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 393 vtNPKTKNI-RLYVKRVFISDDFDGeLFPRYLSFVKGVVDSDDLPLNVSREILQESRIVRIMRKRL---IRktfDMIQEI 468
Cdd:PRK14083 259 --SPAARRKhRVYLKRMLLSEEAEN-LLPDWAFFVRCVVNTDELRPTASREALYEDDALAAVREELgeaIR---KWLIGL 332
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 30678090 469 SESENkekfwENFGRFLK---LG----CIEDTGNHKRITPLLRFFSSKNEEeltSLDDYIENMGEnqkaIYYLAT 536
Cdd:PRK14083 333 ATTDP-----ERLRRLLAvhhLGvkalASHDDELLRLILPWLPFETTDGRM---TLAEIRRRHGV----IRYTSS 395
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
101-211 |
1.97e-09 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 55.73 E-value: 1.97e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 101 EVFLRELVSNASDALDKLRFlsvtepsllgDGGDLEIRIKPDPDNGTITITDTGIGMTKEELidclgtiaqsgtskfLKA 180
Cdd:smart00387 3 PDRLRQVLSNLLDNAIKYTP----------EGGRITVTLERDGDHVEITVEDNGPGIPPEDL---------------EKI 57
|
90 100 110
....*....|....*....|....*....|.
gi 30678090 181 LKENKDLGADNGLIGQFGVGFYSAFLVAEKV 211
Cdd:smart00387 58 FEPFFRTDKRSRKIGGTGLGLSIVKKLVELH 88
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
100-162 |
3.48e-06 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 46.21 E-value: 3.48e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30678090 100 KEVFLRELVSNASDALDKLRflsvtepsllGDGGDLEIRIKPDpDNGTITITDTGIGMTKEEL 162
Cdd:pfam02518 2 DELRLRQVLSNLLDNALKHA----------AKAGEITVTLSEG-GELTLTVEDNGIGIPPEDL 53
|
|
| HATPase_TopVIB-like |
cd16933 |
Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family ... |
105-282 |
9.17e-06 |
|
Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family includes the histidine kinase-like ATPase (HATPase) domain of the B subunit of topoisomerase VI (Topo VIB). Topo VI is a heterotetrameric complex composed of two TopVIA and two TopVIB subunits and is categorized as a type II B DNA topoisomerase. It is found in archaea and also in plants. Type II enzymes cleave both strands of a DNA duplex and pass a second duplex through the resulting break in an ATP-dependent mechanism. DNA cleavage by Topo VI generates two-nucleotide 5'-protruding ends.
Pssm-ID: 340410 [Multi-domain] Cd Length: 203 Bit Score: 47.34 E-value: 9.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 105 RELVSNASDALDklrflsvtEPSLLGDggdLEIRI-KPDPDNGTITITDTGIGMTKEELIDCLGTIAQSgtSKFlkALKE 183
Cdd:cd16933 25 RELVENSLDATE--------EAGILPD---IKVEIeEIGKDHYKVIVEDNGPGIPEEQIPKVFGKVLYG--SKY--HNKQ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 184 NKdlgadngliGQFGVGFYSAFLVAE-----KVVVSTKSPKSDKQYVWESVADSSSY--LIREETDPDNILR-RGTQITL 255
Cdd:cd16933 90 SR---------GQQGLGISAAVLYSQmttgkPVEIISSTKDSNYAYVVKLMIDTDKNepEILEKEEVENRYKwHGTRVEL 160
|
170 180 190
....*....|....*....|....*....|...
gi 30678090 256 YLREDDK------YEFAESTRIknlVKNYSQFV 282
Cdd:cd16933 161 ELEGNWVaarsqiLEYYKRTAV---IAPYAEII 190
|
|
| HATPase_c_3 |
pfam13589 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, ... |
101-237 |
2.02e-05 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433332 [Multi-domain] Cd Length: 135 Bit Score: 45.01 E-value: 2.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 101 EVFLRELVSNASDAldklrflsvtepsllgDGGDLEIRIKPDPDNGT-ITITDTGIGMTKEELIDCLGtIAQSgtskflk 179
Cdd:pfam13589 2 EGALAELIDNSIDA----------------DATNIKIEVNKNRGGGTeIVIEDDGHGMSPEELINALR-LATS------- 57
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30678090 180 alkeNKDLGADNGLIGQFGVGFYSAFLV-AEKVVVSTKspKSDKQYV----WESVADSSSYLI 237
Cdd:pfam13589 58 ----AKEAKRGSTDLGRYGIGLKLASLSlGAKLTVTSK--KEGKSSTltldRDKISNENDWLL 114
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
107-162 |
8.43e-05 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 45.56 E-value: 8.43e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 30678090 107 LVSNASDALDKlrflsvtepsllGDGGDLEIRIKPDPDNGTITITDTGIGMTKEEL 162
Cdd:COG4191 264 LLINAIDAMEE------------GEGGRITISTRREGDYVVISVRDNGPGIPPEVL 307
|
|
| HATPase_MORC-like |
cd16931 |
Histidine kinase-like ATPase domain of human microrchidia (MORC) family CW-type zinc finger ... |
98-220 |
1.28e-04 |
|
Histidine kinase-like ATPase domain of human microrchidia (MORC) family CW-type zinc finger proteins MORC1-4, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domain of human microrchidia (MORC) family CW-type zinc finger proteins MORC1-4, and related domains. In addition to the HATPase domain, MORC family proteins have a CW-type zinc finger domain containing four conserved cysteines and two conserved tryptophans, and coiled-coil domains at the carboxy-terminus. MORC1 has cross-species differential methylation in association with early life stress, and genome-wide association with major depressive disorder (MDD). MORC2 is involved in several nuclear processes, including transcription modulation and DNA damage repair, and exhibits a cytosolic function in lipogenesis, adipogenic differentiation, and lipid homeostasis by increasing the activity of ACLY. MORC3 regulates p53, and is an antiviral factor which plays an important role during HSV-1 and HCMV infection, and is a positive regulator of influenza virus transcription. MORC4 is highly expressed in a subset of diffuse large B-cell lymphomas and has potential as a lymphoma biomarker.
Pssm-ID: 340408 [Multi-domain] Cd Length: 118 Bit Score: 42.01 E-value: 1.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 98 SHKEVF--LRELVSNASDAldklrflsvtepsllgDGGDLEIRI--KPDPDNGT-ITITDTGIGMTKEELIDCLGtiaqs 172
Cdd:cd16931 8 THSWPFgaVAELVDNARDA----------------DATRLDIFIddINLLRGGFmLSFLDDGNGMTPEEAHHMIS----- 66
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 30678090 173 gtskFLKALKENKDLGAdnglIGQFGVGFYS-AFLVAEKVVVSTKSPKS 220
Cdd:cd16931 67 ----FGFSDKRSDDHDH----IGRYGNGFKSgSMRLGRDVIVFTKKDES 107
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
104-162 |
1.90e-04 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 44.51 E-value: 1.90e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 30678090 104 LRELVSNAsdaldkLRFlsvTEPsllgdGGDLEIRIKPDPDNGTITITDTGIGMTKEEL 162
Cdd:COG0642 228 LLNLLSNA------IKY---TPE-----GGTVTVSVRREGDRVRISVEDTGPGIPPEDL 272
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
131-162 |
2.88e-04 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 44.09 E-value: 2.88e-04
10 20 30
....*....|....*....|....*....|..
gi 30678090 131 DGGDLEIRIKPDPDNGTITITDTGIGMTKEEL 162
Cdd:COG5806 329 NGGTLTIDVSIDKNKVIISIKDTGVGMTKEQL 360
|
|
| PRK04184 |
PRK04184 |
DNA topoisomerase VI subunit B; Validated |
104-263 |
3.33e-04 |
|
DNA topoisomerase VI subunit B; Validated
Pssm-ID: 235246 [Multi-domain] Cd Length: 535 Bit Score: 44.11 E-value: 3.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 104 LRELVSNASDALDKLRFLsvtePSLLgdggdLEI-RIKPDPDNGTITITDTGIGMTKEELIDCLGTIAQSgtSKFlKALK 182
Cdd:PRK04184 41 VKELVDNSLDACEEAGIL----PDIK-----IEIkRVDEGKDHYRVTVEDNGPGIPPEEIPKVFGKLLYG--SKF-HNLR 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30678090 183 ENKdlgadngliGQFGVGFYSAFLVA-----EKVVVSTKSPKSDKQYVWESVADSSS----YLIREETDPDNilRRGTQI 253
Cdd:PRK04184 109 QSR---------GQQGIGISAAVLYAqmttgKPVRVISSTGGSKKAYYFELKIDTKKnepiILEREEVDWDR--WHGTRV 177
|
170
....*....|
gi 30678090 254 TLYLrEDDKY 263
Cdd:PRK04184 178 ELEI-EGDWY 186
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
104-162 |
2.25e-03 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 40.28 E-value: 2.25e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 30678090 104 LRELVSNAsdaldkLRFlsvTEPsllgdGGDLEIRIKPDPDNGTITITDTGIGMTKEEL 162
Cdd:COG2205 137 LANLLDNA------IKY---SPP-----GGTITISARREGDGVRISVSDNGPGIPEEEL 181
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
107-162 |
2.74e-03 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 40.72 E-value: 2.74e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 30678090 107 LVSNASDALDklrflsvtepsllgDGGDLEIRIKPDPDNGTITITDTGIGMTKEEL 162
Cdd:COG5000 325 LLKNAIEAIE--------------EGGEIEVSTRREDGRVRIEVSDNGPGIPEEVL 366
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
107-162 |
2.86e-03 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 40.69 E-value: 2.86e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 30678090 107 LVSNAsdaldkLRFlsvTEPsllgdGGDLEIRIKPDPDNGTITITDTGIGMTKEEL 162
Cdd:COG5002 289 LLDNA------IKY---TPE-----GGTITVSLREEDDQVRISVRDTGIGIPEEDL 330
|
|
| |
