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Conserved domains on  [gi|30686497|ref|NP_849691|]
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Mannose-binding lectin superfamily protein [Arabidopsis thaliana]

Protein Classification

jacalin family lectin( domain architecture ID 10176320)

jacalin family lectin is a sugar-binding protein containing a jacalin domain

Gene Ontology:  GO:0030246
PubMed:  15329359|28737678
SCOP:  4002758

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 18-146 1.62e-38

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


:

Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 138.08  E-value: 1.62e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497  18 GHAWDDGMYTT-VKQIIIAHG-SGIDSIQIEYDKNGSSVWSEKRGGKGGKKFDKVkFDYPHEYLISVNGTYGSFdvWGTI 95
Cdd:cd09612   1 GSAWDDGVFPDgLRKITVRSGeNGIDSIKFEYDKDGQHVVGPWHGGGGGTPEEIV-LDYPDEYITSVSGTYGPV--SGSN 77

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 30686497  96 CVRSLTFESNRRKYGPFGVDSGTFFALPKSGSKIIGFHGKAGWYLDAIGVH 146
Cdd:cd09612  78 VITSLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVY 128
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 248-374 1.21e-36

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


:

Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 133.08  E-value: 1.21e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497 248 FDDGIY-TGIRQINLSRNV-GIVSMKVCYDFRGQAVWGSKHGGVGGFKhDKIVFDYPSEVLTHVTGTYGPlmYMGPNVIK 325
Cdd:cd09612   4 WDDGVFpDGLRKITVRSGEnGIDSIKFEYDKDGQHVVGPWHGGGGGTP-EEIVLDYPDEYITSVSGTYGP--VSGSNVIT 80

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*....
gi 30686497 326 SLTFRTNRGKHGPYGEEQGPSFTHQMDEGKVVGFLGREGLFLDSIGVHV 374
Cdd:cd09612  81 SLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYV 129
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 444-576 2.32e-36

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


:

Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 132.30  E-value: 2.32e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497 444 QAWDDGVF-SGIKQIFVTRGNDAITSIQIEYDRNGQSVWSIKHGGdsNGVATHRIKFEYPDESITCISGYYGPLNnsdRY 522
Cdd:cd09612   2 SAWDDGVFpDGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHGG--GGGTPEEIVLDYPDEYITSVSGTYGPVS---GS 76

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 30686497 523 NVVKSLSFYTSRGRYGPYGEETGTFFTSTTTQGKVLGFHGRSSFHLDAIGVHMQ 576
Cdd:cd09612  77 NVITSLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYVS 130
 
Name Accession Description Interval E-value
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 18-146 1.62e-38

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 138.08  E-value: 1.62e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497  18 GHAWDDGMYTT-VKQIIIAHG-SGIDSIQIEYDKNGSSVWSEKRGGKGGKKFDKVkFDYPHEYLISVNGTYGSFdvWGTI 95
Cdd:cd09612   1 GSAWDDGVFPDgLRKITVRSGeNGIDSIKFEYDKDGQHVVGPWHGGGGGTPEEIV-LDYPDEYITSVSGTYGPV--SGSN 77

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 30686497  96 CVRSLTFESNRRKYGPFGVDSGTFFALPKSGSKIIGFHGKAGWYLDAIGVH 146
Cdd:cd09612  78 VITSLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVY 128
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 248-374 1.21e-36

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 133.08  E-value: 1.21e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497 248 FDDGIY-TGIRQINLSRNV-GIVSMKVCYDFRGQAVWGSKHGGVGGFKhDKIVFDYPSEVLTHVTGTYGPlmYMGPNVIK 325
Cdd:cd09612   4 WDDGVFpDGLRKITVRSGEnGIDSIKFEYDKDGQHVVGPWHGGGGGTP-EEIVLDYPDEYITSVSGTYGP--VSGSNVIT 80

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*....
gi 30686497 326 SLTFRTNRGKHGPYGEEQGPSFTHQMDEGKVVGFLGREGLFLDSIGVHV 374
Cdd:cd09612  81 SLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYV 129
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 444-576 2.32e-36

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 132.30  E-value: 2.32e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497 444 QAWDDGVF-SGIKQIFVTRGNDAITSIQIEYDRNGQSVWSIKHGGdsNGVATHRIKFEYPDESITCISGYYGPLNnsdRY 522
Cdd:cd09612   2 SAWDDGVFpDGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHGG--GGGTPEEIVLDYPDEYITSVSGTYGPVS---GS 76

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 30686497 523 NVVKSLSFYTSRGRYGPYGEETGTFFTSTTTQGKVLGFHGRSSFHLDAIGVHMQ 576
Cdd:cd09612  77 NVITSLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYVS 130
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 18-149 1.76e-32

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 121.61  E-value: 1.76e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497    18 GHAWDDGMYTTVKQI-IIAHGSGIDSIQIEYDKNGSSVWSEKRGGKGGKKFDKVKFDYPHEYLISVNGTYGSFDVWGTIC 96
Cdd:pfam01419   1 GASWDDGVYDGVRKVyVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSDSEV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 30686497    97 VRSLTFESNRRKYGP-FGVDSGTFFALPKSGSKIIGFHGKAGWYLDAIGVHTQP 149
Cdd:pfam01419  81 ITSLTFKTNKGRTSPfFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYFAP 134
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 245-374 4.64e-31

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 117.33  E-value: 4.64e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497    245 GIMFDDGIYTGIRQINLSRN-VGIVSMKVCYDFrGQAVWGSKHGGVGGfkHDKIVFDYPSEVLTHVTGTYGPLmymgpNV 323
Cdd:smart00915   1 GTEWDDGAFDGVRKIYVGQGgEGIKSIQFDYDK-GGKVWGDEHGGKGG--TGEEILLYPGEYITSVEGTYDKS-----GV 72

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 30686497    324 IKSLTFRTNRGKHGP-YGEEQGPSFTHQMDEG-KVVGFLGRE-GLFLDSIGVHV 374
Cdd:smart00915  73 ITSLTFKTNKGRTSPfGGYEGGTKFVLESKEGkKIVGFHGRSsGDGLDSLGAYF 126
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 18-149 2.01e-30

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 115.40  E-value: 2.01e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497     18 GHAWDDGMYTTVKQIIIAHG-SGIDSIQIEYDKNGsSVWSEkrGGKGGKKFDKVKFDYPHEYLISVNGTYGSfdvwgTIC 96
Cdd:smart00915   1 GTEWDDGAFDGVRKIYVGQGgEGIKSIQFDYDKGG-KVWGD--EHGGKGGTGEEILLYPGEYITSVEGTYDK-----SGV 72

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 30686497     97 VRSLTFESNRRKYGP-FGVDSGTFFALP-KSGSKIIGFHG-KAGWYLDAIGVHTQP 149
Cdd:smart00915  73 ITSLTFKTNKGRTSPfGGYEGGTKFVLEsKEGKKIVGFHGrSSGDGLDSLGAYFSP 128
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 446-574 6.21e-30

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 114.25  E-value: 6.21e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497    446 WDDGVFSGIKQIFVTRGNDAITSIQIEYDrNGQSVWSIKHGGDSNgvaTHRIKFEYPDESITCISGYYGPlnnsdrYNVV 525
Cdd:smart00915   4 WDDGAFDGVRKIYVGQGGEGIKSIQFDYD-KGGKVWGDEHGGKGG---TGEEILLYPGEYITSVEGTYDK------SGVI 73

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 30686497    526 KSLSFYTSRGRYGP-YGEETGTFFTSTTTQGKVL-GFHGRSS-FHLDAIGVH 574
Cdd:smart00915  74 TSLTFKTNKGRTSPfGGYEGGTKFVLESKEGKKIvGFHGRSSgDGLDSLGAY 125
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 445-574 3.00e-28

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 109.67  E-value: 3.00e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497   445 AWDDGVFSGIKQIFVTRGNDAITSIQIEYDRNGQSVWSIKHgGDSNGVATHRIKFEYPDESITCISGYYGPLNNSDrYNV 524
Cdd:pfam01419   3 SWDDGVYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEH-GKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSD-SEV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 30686497   525 VKSLSFYTSRGRYGPYGEETGTFFTSTTTQG-KVLGFHGRSSFHLDAIGVH 574
Cdd:pfam01419  81 ITSLTFKTNKGRTSPFFGTPSGTKFSLEVKGkKIVGFHGRAGNALNALGAY 131
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 248-374 4.70e-27

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 106.21  E-value: 4.70e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497   248 FDDGIYTGIRQINLSR-NVGIVSMKVCYDFRGQAVWGSKHGGVGGFKHDKIVFDYPSEVLTHVTGTYGPLMYMGPNVIKS 326
Cdd:pfam01419   4 WDDGVYDGVRKVYVGQgGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSDSEVITS 83

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 30686497   327 LTFRTNRGKHGP-YGEEQGPSFTHQMDEGKVVGFLGREGLFLDSIGVHV 374
Cdd:pfam01419  84 LTFKTNKGRTSPfFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYF 132
PLN02193 PLN02193
nitrile-specifier protein
 445-575 9.17e-10

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 61.12  E-value: 9.17e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497  445 AWDDGVFSGIKQIFVTRGNDAITSIQIEYDRNGQSVWSIKHGGDSN-GVATHRIKfeyPDESITCISGYYGPLNNSDRyN 523
Cdd:PLN02193  15 VWDDGVYDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVGDEHGKKTElGVEEFEID---ADDYIVYVEGYREKVNDMTS-E 90

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 30686497  524 VVKSLSFYTSRGRYGPYGEETGTFFTSTTTqGKVLGFHGRSSFHLDAIGVHM 575
Cdd:PLN02193  91 MITFLSFKTYKGKTSHPIEKRPGVKFVLQG-GKIVGFHGRSTDVLHSLGAYI 141
PLN02193 PLN02193
nitrile-specifier protein
 241-374 3.74e-09

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 59.20  E-value: 3.74e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497  241 GGTGGIMFDDGIYTGIRQINLSR-NVGIVSMKVCYDFRGQAVWGSKHG-----GVGGFKHDkivfdyPSEVLTHVTGTYG 314
Cdd:PLN02193   9 GGETGDVWDDGVYDNVRKVYVGQgQYGIAFVKFEYVNGSQVVVGDEHGkktelGVEEFEID------ADDYIVYVEGYRE 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30686497  315 PLMYMGPNVIKSLTFRTNRGKHG-PYGEEQGPSFTHQmdEGKVVGFLGREGLFLDSIGVHV 374
Cdd:PLN02193  83 KVNDMTSEMITFLSFKTYKGKTShPIEKRPGVKFVLQ--GGKIVGFHGRSTDVLHSLGAYI 141
PLN02193 PLN02193
nitrile-specifier protein
 14-160 4.20e-08

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 55.73  E-value: 4.20e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497   14 GGQSGHAWDDGMYTTVKQIIIAHGS-GIDSIQIEYDKNGSSVWSEKRGGKGGKKFDKVKFDyPHEYLISVNGTYGSFDVW 92
Cdd:PLN02193   9 GGETGDVWDDGVYDNVRKVYVGQGQyGIAFVKFEYVNGSQVVVGDEHGKKTELGVEEFEID-ADDYIVYVEGYREKVNDM 87

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30686497   93 GTICVRSLTFESNRRKYG-PFGVDSGTFFALpkSGSKIIGFHGKAGWYLDAIG--VHTQPIPKENNPSSKI 160
Cdd:PLN02193  88 TSEMITFLSFKTYKGKTShPIEKRPGVKFVL--QGGKIVGFHGRSTDVLHSLGayISLPSTPKLLGKWIKV 156
 
Name Accession Description Interval E-value
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 18-146 1.62e-38

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 138.08  E-value: 1.62e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497  18 GHAWDDGMYTT-VKQIIIAHG-SGIDSIQIEYDKNGSSVWSEKRGGKGGKKFDKVkFDYPHEYLISVNGTYGSFdvWGTI 95
Cdd:cd09612   1 GSAWDDGVFPDgLRKITVRSGeNGIDSIKFEYDKDGQHVVGPWHGGGGGTPEEIV-LDYPDEYITSVSGTYGPV--SGSN 77

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 30686497  96 CVRSLTFESNRRKYGPFGVDSGTFFALPKSGSKIIGFHGKAGWYLDAIGVH 146
Cdd:cd09612  78 VITSLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVY 128
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 248-374 1.21e-36

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 133.08  E-value: 1.21e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497 248 FDDGIY-TGIRQINLSRNV-GIVSMKVCYDFRGQAVWGSKHGGVGGFKhDKIVFDYPSEVLTHVTGTYGPlmYMGPNVIK 325
Cdd:cd09612   4 WDDGVFpDGLRKITVRSGEnGIDSIKFEYDKDGQHVVGPWHGGGGGTP-EEIVLDYPDEYITSVSGTYGP--VSGSNVIT 80

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*....
gi 30686497 326 SLTFRTNRGKHGPYGEEQGPSFTHQMDEGKVVGFLGREGLFLDSIGVHV 374
Cdd:cd09612  81 SLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYV 129
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
 444-576 2.32e-36

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 132.30  E-value: 2.32e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497 444 QAWDDGVF-SGIKQIFVTRGNDAITSIQIEYDRNGQSVWSIKHGGdsNGVATHRIKFEYPDESITCISGYYGPLNnsdRY 522
Cdd:cd09612   2 SAWDDGVFpDGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHGG--GGGTPEEIVLDYPDEYITSVSGTYGPVS---GS 76

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 30686497 523 NVVKSLSFYTSRGRYGPYGEETGTFFTSTTTQGKVLGFHGRSSFHLDAIGVHMQ 576
Cdd:cd09612  77 NVITSLTFKTNKRTYGPFGVESGTPFSLPVEGGKIVGFHGRSGDYLDAIGVYVS 130
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 18-149 1.76e-32

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 121.61  E-value: 1.76e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497    18 GHAWDDGMYTTVKQI-IIAHGSGIDSIQIEYDKNGSSVWSEKRGGKGGKKFDKVKFDYPHEYLISVNGTYGSFDVWGTIC 96
Cdd:pfam01419   1 GASWDDGVYDGVRKVyVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSDSEV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 30686497    97 VRSLTFESNRRKYGP-FGVDSGTFFALPKSGSKIIGFHGKAGWYLDAIGVHTQP 149
Cdd:pfam01419  81 ITSLTFKTNKGRTSPfFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYFAP 134
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 245-374 4.64e-31

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 117.33  E-value: 4.64e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497    245 GIMFDDGIYTGIRQINLSRN-VGIVSMKVCYDFrGQAVWGSKHGGVGGfkHDKIVFDYPSEVLTHVTGTYGPLmymgpNV 323
Cdd:smart00915   1 GTEWDDGAFDGVRKIYVGQGgEGIKSIQFDYDK-GGKVWGDEHGGKGG--TGEEILLYPGEYITSVEGTYDKS-----GV 72

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....
gi 30686497    324 IKSLTFRTNRGKHGP-YGEEQGPSFTHQMDEG-KVVGFLGRE-GLFLDSIGVHV 374
Cdd:smart00915  73 ITSLTFKTNKGRTSPfGGYEGGTKFVLESKEGkKIVGFHGRSsGDGLDSLGAYF 126
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 18-149 2.01e-30

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 115.40  E-value: 2.01e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497     18 GHAWDDGMYTTVKQIIIAHG-SGIDSIQIEYDKNGsSVWSEkrGGKGGKKFDKVKFDYPHEYLISVNGTYGSfdvwgTIC 96
Cdd:smart00915   1 GTEWDDGAFDGVRKIYVGQGgEGIKSIQFDYDKGG-KVWGD--EHGGKGGTGEEILLYPGEYITSVEGTYDK-----SGV 72

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 30686497     97 VRSLTFESNRRKYGP-FGVDSGTFFALP-KSGSKIIGFHG-KAGWYLDAIGVHTQP 149
Cdd:smart00915  73 ITSLTFKTNKGRTSPfGGYEGGTKFVLEsKEGKKIVGFHGrSSGDGLDSLGAYFSP 128
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
 446-574 6.21e-30

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 114.25  E-value: 6.21e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497    446 WDDGVFSGIKQIFVTRGNDAITSIQIEYDrNGQSVWSIKHGGDSNgvaTHRIKFEYPDESITCISGYYGPlnnsdrYNVV 525
Cdd:smart00915   4 WDDGAFDGVRKIYVGQGGEGIKSIQFDYD-KGGKVWGDEHGGKGG---TGEEILLYPGEYITSVEGTYDK------SGVI 73

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 30686497    526 KSLSFYTSRGRYGP-YGEETGTFFTSTTTQGKVL-GFHGRSS-FHLDAIGVH 574
Cdd:smart00915  74 TSLTFKTNKGRTSPfGGYEGGTKFVLESKEGKKIvGFHGRSSgDGLDSLGAY 125
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 445-574 3.00e-28

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 109.67  E-value: 3.00e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497   445 AWDDGVFSGIKQIFVTRGNDAITSIQIEYDRNGQSVWSIKHgGDSNGVATHRIKFEYPDESITCISGYYGPLNNSDrYNV 524
Cdd:pfam01419   3 SWDDGVYDGVRKVYVGQGGDGITYIKFEYVKGGGKVEGDEH-GKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSD-SEV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 30686497   525 VKSLSFYTSRGRYGPYGEETGTFFTSTTTQG-KVLGFHGRSSFHLDAIGVH 574
Cdd:pfam01419  81 ITSLTFKTNKGRTSPFFGTPSGTKFSLEVKGkKIVGFHGRAGNALNALGAY 131
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
 248-374 4.70e-27

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 106.21  E-value: 4.70e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497   248 FDDGIYTGIRQINLSR-NVGIVSMKVCYDFRGQAVWGSKHGGVGGFKHDKIVFDYPSEVLTHVTGTYGPLMYMGPNVIKS 326
Cdd:pfam01419   4 WDDGVYDGVRKVYVGQgGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSDSEVITS 83

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 30686497   327 LTFRTNRGKHGP-YGEEQGPSFTHQMDEGKVVGFLGREGLFLDSIGVHV 374
Cdd:pfam01419  84 LTFKTNKGRTSPfFGTPSGTKFSLEVKGKKIVGFHGRAGNALNALGAYF 132
PLN02193 PLN02193
nitrile-specifier protein
 445-575 9.17e-10

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 61.12  E-value: 9.17e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497  445 AWDDGVFSGIKQIFVTRGNDAITSIQIEYDRNGQSVWSIKHGGDSN-GVATHRIKfeyPDESITCISGYYGPLNNSDRyN 523
Cdd:PLN02193  15 VWDDGVYDNVRKVYVGQGQYGIAFVKFEYVNGSQVVVGDEHGKKTElGVEEFEID---ADDYIVYVEGYREKVNDMTS-E 90

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 30686497  524 VVKSLSFYTSRGRYGPYGEETGTFFTSTTTqGKVLGFHGRSSFHLDAIGVHM 575
Cdd:PLN02193  91 MITFLSFKTYKGKTSHPIEKRPGVKFVLQG-GKIVGFHGRSTDVLHSLGAYI 141
PLN02193 PLN02193
nitrile-specifier protein
 241-374 3.74e-09

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 59.20  E-value: 3.74e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497  241 GGTGGIMFDDGIYTGIRQINLSR-NVGIVSMKVCYDFRGQAVWGSKHG-----GVGGFKHDkivfdyPSEVLTHVTGTYG 314
Cdd:PLN02193   9 GGETGDVWDDGVYDNVRKVYVGQgQYGIAFVKFEYVNGSQVVVGDEHGkktelGVEEFEID------ADDYIVYVEGYRE 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30686497  315 PLMYMGPNVIKSLTFRTNRGKHG-PYGEEQGPSFTHQmdEGKVVGFLGREGLFLDSIGVHV 374
Cdd:PLN02193  83 KVNDMTSEMITFLSFKTYKGKTShPIEKRPGVKFVLQ--GGKIVGFHGRSTDVLHSLGAYI 141
PLN02193 PLN02193
nitrile-specifier protein
 14-160 4.20e-08

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 55.73  E-value: 4.20e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497   14 GGQSGHAWDDGMYTTVKQIIIAHGS-GIDSIQIEYDKNGSSVWSEKRGGKGGKKFDKVKFDyPHEYLISVNGTYGSFDVW 92
Cdd:PLN02193   9 GGETGDVWDDGVYDNVRKVYVGQGQyGIAFVKFEYVNGSQVVVGDEHGKKTELGVEEFEID-ADDYIVYVEGYREKVNDM 87

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30686497   93 GTICVRSLTFESNRRKYG-PFGVDSGTFFALpkSGSKIIGFHGKAGWYLDAIG--VHTQPIPKENNPSSKI 160
Cdd:PLN02193  88 TSEMITFLSFKTYKGKTShPIEKRPGVKFVL--QGGKIVGFHGRSTDVLHSLGayISLPSTPKLLGKWIKV 156
Jacalin_like cd09302
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly ...
 448-573 9.41e-08

Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. Taxonomic distribution is not restricted to plants, the domain is also found in various mammalian proteins, for example.


Pssm-ID: 187706  Cd Length: 128  Bit Score: 50.86  E-value: 9.41e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497 448 DGVFSGIKQIFVtRGNDAITSIQIEYDrngqSVWSIKHGGdsNGVATHRIKFEYPDESITCISGYYGplnNSDRYNVVKS 527
Cdd:cd09302   8 GGDGARLTEIRV-RSGGAVDAIRVVLR----DYTDGRHGG--NGGPNTSSVFLDPGEYITITSVSSG---DNGGGTRIDA 77

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 30686497 528 LSFYTSRGRYGPYGEETGTFFTSTTTQ--GKVLGFHGRSSFHLDAIGV 573
Cdd:cd09302  78 IQFTTNKGRSGTYGTTSGALGTEFTVPvgGEIVGIYGRAGDDVDAFGF 125
Jacalin_like cd09302
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly ...
 27-145 2.52e-07

Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. Taxonomic distribution is not restricted to plants, the domain is also found in various mammalian proteins, for example.


Pssm-ID: 187706  Cd Length: 128  Bit Score: 49.71  E-value: 2.52e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497  27 TTVKQIIIAHGSGIDSIQIEYDkngsSVWSEKRGGKGGKKFDKVKFDyPHEYLISVNGTYGsfDVWGTICVRSLTFESNR 106
Cdd:cd09302  12 ARLTEIRVRSGGAVDAIRVVLR----DYTDGRHGGNGGPNTSSVFLD-PGEYITITSVSSG--DNGGGTRIDAIQFTTNK 84

                        90       100       110       120
                ....*....|....*....|....*....|....*....|..
gi 30686497 107 RKYGPFGVDS---GTFFALPkSGSKIIGFHGKAGWYLDAIGV 145
Cdd:cd09302  85 GRSGTYGTTSgalGTEFTVP-VGGEIVGIYGRAGDDVDAFGF 125
Jacalin_like cd09302
Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly ...
 245-372 1.94e-06

Jacalin-like lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. Taxonomic distribution is not restricted to plants, the domain is also found in various mammalian proteins, for example.


Pssm-ID: 187706  Cd Length: 128  Bit Score: 47.40  E-value: 1.94e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497 245 GIMFDD--GIYTGIRQINLSRNVGIVSMKVCYDfrgqAVWGSKHGGVGGFKHDKIVFDyPSEVLTHVTGTYGplMYMGPN 322
Cdd:cd09302   1 GKPFSDtgGDGARLTEIRVRSGGAVDAIRVVLR----DYTDGRHGGNGGPNTSSVFLD-PGEYITITSVSSG--DNGGGT 73

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 30686497 323 VIKSLTFRTNRGKHGPYGEEQGPS-FTHQMDEG-KVVGFLGREGLFLDSIGV 372
Cdd:cd09302  74 RIDAIQFTTNKGRSGTYGTTSGALgTEFTVPVGgEIVGIYGRAGDDVDAFGF 125
griffithsin_like cd09614
Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin ...
 15-146 6.24e-06

Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin isolated from a red alga, which has shown potential as an inhibitor of viral entry, exhibiting antiviral activity against HIV and SARS. The biological functions of griffithsin and griffithsin-like proteins with respect to their source organisms are not known.


Pssm-ID: 187710  Cd Length: 128  Bit Score: 45.85  E-value: 6.24e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497  15 GQSGHAWDDGMYTTVKQIIIAHGSGIDSIQIEY-DKNGSSVWSEKRGGKGGKKFDKVkfdYPHEYLISVNGTYGSFdvwg 93
Cdd:cd09614   1 GFGGSPGSDFDILTVSAIQLRSGSYVDQIITDYqDLNGTQNFHHGGGGGNLSPTLNF---SSGEYITEVTGRSGDR---- 73

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 30686497  94 ticVRSLTFESNR-RKYGPFGVDSGTFFAL-PKSGSKIIGFHGKAGWYLDAIGVH 146
Cdd:cd09614  74 ---VDQVQFTTNYgGRTLPGGGGGGSAFTWtVPDNQKVIGFAGRSGSYLDQLQVY 125
griffithsin_like cd09614
Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin ...
 242-374 1.24e-05

Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin isolated from a red alga, which has shown potential as an inhibitor of viral entry, exhibiting antiviral activity against HIV and SARS. The biological functions of griffithsin and griffithsin-like proteins with respect to their source organisms are not known.


Pssm-ID: 187710  Cd Length: 128  Bit Score: 45.08  E-value: 1.24e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497 242 GTGGIMFDDGIYTGIRQINLSRNVGIVSMKVCYDFRGQAVWGsKHGGVGGFKHDKIVFdYPSEVLTHVTGTYGplmymgp 321
Cdd:cd09614   1 GFGGSPGSDFDILTVSAIQLRSGSYVDQIITDYQDLNGTQNF-HHGGGGGNLSPTLNF-SSGEYITEVTGRSG------- 71

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 30686497 322 NVIKSLTFRTNRG-KHGPYGEEQGPSFTHQMDEG-KVVGFLGREGLFLDSIGVHV 374
Cdd:cd09614  72 DRVDQVQFTTNYGgRTLPGGGGGGSAFTWTVPDNqKVIGFAGRSGSYLDQLQVYY 126
Jacalin_ZG16_like cd09611
Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins; ZG16p is a ...
 454-537 1.25e-05

Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins; ZG16p is a conserved secreted vertebrate protein with tissue-specific expression profiles, which might play a role in glycoprotein secretion, perhaps as a linker protein that participates in the formation and/or transport of the zymogen granule. Its paralog ZG16b (PAUF) has been associated with roles in gene regulation and cancer. This domain family also contains mammalian proteins labelled as prostatic spermine-binding protein (SBP) and salivary-gland specific secreted proteins.


Pssm-ID: 187707 [Multi-domain]  Cd Length: 128  Bit Score: 45.01  E-value: 1.25e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497 454 IKQIFVTRGNDAITSIQIEYDrngqSVWSIKHGGDSnGVATHRikFEYPDESITCISGYYgplnnsdrYNVVKSLSFYTS 533
Cdd:cd09611  18 ITGIRVSVGNNYIKGIQVRYG----SNWSDVYGGRG-GNEQEI--VLEPGESITKVSGSY--------KIYLHGLVFTTN 82


                ....
gi 30686497 534 RGRY 537
Cdd:cd09611  83 KGRY 86
griffithsin_like cd09614
Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin ...
 446-574 2.76e-03

Jacalin-like lectin domain of griffithsin and related proteins; Griffithsin is a lectin isolated from a red alga, which has shown potential as an inhibitor of viral entry, exhibiting antiviral activity against HIV and SARS. The biological functions of griffithsin and griffithsin-like proteins with respect to their source organisms are not known.


Pssm-ID: 187710  Cd Length: 128  Bit Score: 38.15  E-value: 2.76e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497 446 WDDgvFSGIKQIFVT-RGNDAITSIQIEY-DRNGQSvwSIKHGGdsNGVATHRIKFEYPDESITCISGYYGplnnsdryN 523
Cdd:cd09614   7 GSD--FDILTVSAIQlRSGSYVDQIITDYqDLNGTQ--NFHHGG--GGGNLSPTLNFSSGEYITEVTGRSG--------D 72

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|...
gi 30686497 524 VVKSLSFYTSRG-RYGPYGEETGTFFTSTTTQG-KVLGFHGRSSFHLDAIGVH 574
Cdd:cd09614  73 RVDQVQFTTNYGgRTLPGGGGGGSAFTWTVPDNqKVIGFAGRSGSYLDQLQVY 125
Jacalin_ZG16_like cd09611
Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins; ZG16p is a ...
 40-146 8.77e-03

Jacalin-like lectin domain of the zymogen granule protein 16 and related proteins; ZG16p is a conserved secreted vertebrate protein with tissue-specific expression profiles, which might play a role in glycoprotein secretion, perhaps as a linker protein that participates in the formation and/or transport of the zymogen granule. Its paralog ZG16b (PAUF) has been associated with roles in gene regulation and cancer. This domain family also contains mammalian proteins labelled as prostatic spermine-binding protein (SBP) and salivary-gland specific secreted proteins.


Pssm-ID: 187707 [Multi-domain]  Cd Length: 128  Bit Score: 36.92  E-value: 8.77e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30686497  40 IDSIQIEYDKNGSSVWSekrggkGGKKFDKVKFDYPHEYLISVNGTYGsfdvwgtICVRSLTFESNRRKYGPFGVDSGTF 119
Cdd:cd09611  30 IKGIQVRYGSNWSDVYG------GRGGNEQEIVLEPGESITKVSGSYK-------IYLHGLVFTTNKGRYLSFGKLRGRS 96

                        90       100       110
                ....*....|....*....|....*....|
gi 30686497 120 F--ALPKSGSKIIGFHGKAGW-YLDAIGVH 146
Cdd:cd09611  97 FnaTPPPSNYVLRGISGRYGGlGIKSIGFH 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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