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Conserved domains on  [gi|30688819|ref|NP_849476|]
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cyclin-dependent kinase-activating kinase assembly factor-related / CDK-activating kinase assembly factor-like protein [Arabidopsis thaliana]

Protein Classification

MAT1 superfamily-containing protein( domain architecture ID 1907927)

MAT1 superfamily-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MAT1 super family cl44421
CDK-activating kinase assembly factor MAT1; MAT1 is an assembly/targeting factor for ...
 12-81 3.77e-28

CDK-activating kinase assembly factor MAT1; MAT1 is an assembly/targeting factor for cyclin-dependent kinase-activating kinase (CAK), which interacts with the transcription factor TFIIH. The domain found to the N-terminal side of this domain is a C3HC4 RING finger.


The actual alignment was detected with superfamily member pfam06391:

Pssm-ID: 461894 [Multi-domain]  Cd Length: 202  Bit Score: 103.86  E-value: 3.77e-28
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688819    12 KEIHVRRRISEIYNRREEEFPSLKDYNDYLEEVECMVFDLIDGINVEAIEQKIKRYSKENAEQIMINRAR 81
Cdd:pfam06391  18 KEVDIRKRVLKIFNKTEEDFPSLREYNDYLEEVEDIVFNLTNGIDVEETEKKIEQYEKENKDLILKNKMK 87
 
Name Accession Description Interval E-value
MAT1 pfam06391
CDK-activating kinase assembly factor MAT1; MAT1 is an assembly/targeting factor for ...
 12-81 3.77e-28

CDK-activating kinase assembly factor MAT1; MAT1 is an assembly/targeting factor for cyclin-dependent kinase-activating kinase (CAK), which interacts with the transcription factor TFIIH. The domain found to the N-terminal side of this domain is a C3HC4 RING finger.


Pssm-ID: 461894 [Multi-domain]  Cd Length: 202  Bit Score: 103.86  E-value: 3.77e-28
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688819    12 KEIHVRRRISEIYNRREEEFPSLKDYNDYLEEVECMVFDLIDGINVEAIEQKIKRYSKENAEQIMINRAR 81
Cdd:pfam06391  18 KEVDIRKRVLKIFNKTEEDFPSLREYNDYLEEVEDIVFNLTNGIDVEETEKKIEQYEKENKDLILKNKMK 87
cdk7 TIGR00570
CDK-activating kinase assembly factor MAT1; All proteins in this family for which functions ...
 12-81 9.71e-23

CDK-activating kinase assembly factor MAT1; All proteins in this family for which functions are known are cyclin dependent protein kinases that are components of TFIIH, a complex that is involved in nucleotide excision repair and transcription initiation. Also known as MAT1 (menage a trois 1). This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129661 [Multi-domain]  Cd Length: 309  Bit Score: 92.17  E-value: 9.71e-23
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688819    12 KEIHVRRRISEIYNRREEEFPSLKDYNDYLEEVECMVFDLIDGINVEAIEQKIKRYSKENAEQIMINRAR 81
Cdd:TIGR00570  70 KEVDIRKRVLKIYNKREEDFPSLREYNDYLEEVEDIVYNLTNNIDLENTKKKIETYQKENKDVIQKNKEK 139
TFB3 COG5220
Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision ...
 12-81 8.78e-18

Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB3 [Cell division and chromosome partitioning / Transcription / DNA replication, recombination, and repair];


Pssm-ID: 227545 [Multi-domain]  Cd Length: 314  Bit Score: 78.90  E-value: 8.78e-18
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30688819  12 KEIHVRRRISEIYNRREEEF-PSLKDYNDYLEEVECMVFDLIDGINVEAIEQKIKRYSKENAEQIMINRAR 81
Cdd:COG5220  80 KEVDVRKRLLRAFNKEEEEFgGDLAKYNDYLEEVEELVFELLELIDVSLTEEKVKKYEEMNQDSILNNLER 150
 
Name Accession Description Interval E-value
MAT1 pfam06391
CDK-activating kinase assembly factor MAT1; MAT1 is an assembly/targeting factor for ...
 12-81 3.77e-28

CDK-activating kinase assembly factor MAT1; MAT1 is an assembly/targeting factor for cyclin-dependent kinase-activating kinase (CAK), which interacts with the transcription factor TFIIH. The domain found to the N-terminal side of this domain is a C3HC4 RING finger.


Pssm-ID: 461894 [Multi-domain]  Cd Length: 202  Bit Score: 103.86  E-value: 3.77e-28
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688819    12 KEIHVRRRISEIYNRREEEFPSLKDYNDYLEEVECMVFDLIDGINVEAIEQKIKRYSKENAEQIMINRAR 81
Cdd:pfam06391  18 KEVDIRKRVLKIFNKTEEDFPSLREYNDYLEEVEDIVFNLTNGIDVEETEKKIEQYEKENKDLILKNKMK 87
cdk7 TIGR00570
CDK-activating kinase assembly factor MAT1; All proteins in this family for which functions ...
 12-81 9.71e-23

CDK-activating kinase assembly factor MAT1; All proteins in this family for which functions are known are cyclin dependent protein kinases that are components of TFIIH, a complex that is involved in nucleotide excision repair and transcription initiation. Also known as MAT1 (menage a trois 1). This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129661 [Multi-domain]  Cd Length: 309  Bit Score: 92.17  E-value: 9.71e-23
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30688819    12 KEIHVRRRISEIYNRREEEFPSLKDYNDYLEEVECMVFDLIDGINVEAIEQKIKRYSKENAEQIMINRAR 81
Cdd:TIGR00570  70 KEVDIRKRVLKIYNKREEDFPSLREYNDYLEEVEDIVYNLTNNIDLENTKKKIETYQKENKDVIQKNKEK 139
TFB3 COG5220
Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision ...
 12-81 8.78e-18

Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit TFB3 [Cell division and chromosome partitioning / Transcription / DNA replication, recombination, and repair];


Pssm-ID: 227545 [Multi-domain]  Cd Length: 314  Bit Score: 78.90  E-value: 8.78e-18
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30688819  12 KEIHVRRRISEIYNRREEEF-PSLKDYNDYLEEVECMVFDLIDGINVEAIEQKIKRYSKENAEQIMINRAR 81
Cdd:COG5220  80 KEVDVRKRLLRAFNKEEEEFgGDLAKYNDYLEEVEELVFELLELIDVSLTEEKVKKYEEMNQDSILNNLER 150
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 4-70 2.84e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 37.72  E-value: 2.84e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 30688819      4 VSNSTHQNKEIHVRRRISEIYNRREEEFPSLKDyNDYLEEVECMVfdlidgiNVEAIEQKIKRYSKE 70
Cdd:TIGR01612 2497 IKNAAHEIRSEQITKYTNAIHNHIEEQFKKIEN-NSNKDEVYKIN-------EIDNIIEKIINYNKE 2555
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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