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Conserved domains on  [gi|225543504|ref|NP_848505|]
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coiled-coil domain containing 144B isoform 2 [Mus musculus]

Protein Classification

molecular chaperone DnaK( domain architecture ID 10572185)

molecular chaperone protein similar to Escherichia coli DnaK, mitochondrial HSPA9/HSP70, and Saccharomyces cerevisiae Stress-Seventy subfamily C/Ssc1p

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF3496 pfam12001
Domain of unknown function (DUF3496); This presumed domain is functionally uncharacterized. ...
382-484 4.50e-39

Domain of unknown function (DUF3496); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is about 110 amino acids in length.


:

Pssm-ID: 463425 [Multi-domain]  Cd Length: 109  Bit Score: 137.87  E-value: 4.50e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504  382 RTQMELRIKDLESEFSKMK-SQVDCNQIEMENYKQLYLAEVKIRKSLSNKLSKTDERLAEVKTKLLLERKQYRaSQYSMV 460
Cdd:pfam12001   1 RSQMELRIKDLESELSKMKtSQEDSNKIELEKYKQLYLEELKVRKSLSNKLNKTNERLAEVSTKLLVEKQQNR-SLLSTL 79
                          90       100       110
                  ....*....|....*....|....*....|
gi 225543504  461 DTRPALEPTCPRD------SNKFFIPRSFS 484
Cdd:pfam12001  80 TTRPVLESPCVGNlnnslvLNRNFIPRENL 109
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
70-428 6.67e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 6.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504    70 LEKLQTVENEVNGLRKKLaDAAREQLQQGQELcnvrftlkqEEEKRKNVVWVYDKMKEQLREKEDQYNKEVKmkqKLEIR 149
Cdd:TIGR02168  188 LDRLEDILNELERQLKSL-ERQAEKAERYKEL---------KAELRELELALLVLRLEELREELEELQEELK---EAEEE 254
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504   150 VRELDMDLKTVRHNLNTVLEERNCIERQLFQEQntriiqdEILANHLHKQKELKMAQEKISSQLQEAPDQHTQCTEKmrd 229
Cdd:TIGR02168  255 LEELTAELQELEEKLEELRLEVSELEEEIEELQ-------KELYALANEISRLEQQKQILRERLANLERQLEELEAQ--- 324
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504   230 cIQKLGLENHKLKETARKQAEKIEQLKKNLlsgvlsDDLTEKLESASAKYLHLYEQNQLLRRELLSMRtiqRKCEKLKKH 309
Cdd:TIGR02168  325 -LEELESKLDELAEELAELEEKLEELKEEL------ESLEAELEELEAELEELESRLEELEEQLETLR---SKVAQLELQ 394
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504   310 KKKLEQEVVSLRSHMK----RNMIECGQIEQYKWEIEEKTKQELVGKLKQVNLFL-QTQAAYEDKLEKLRQKQNAsvRTQ 384
Cdd:TIGR02168  395 IASLNNEIERLEARLErledRRERLQQEIEELLKKLEEAELKELQAELEELEEELeELQEELERLEEALEELREE--LEE 472
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 225543504   385 MELRIKDLESEFSKMKSQVDCNQIEMENYKQLYLAEVKIRKSLS 428
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQS 516
 
Name Accession Description Interval E-value
DUF3496 pfam12001
Domain of unknown function (DUF3496); This presumed domain is functionally uncharacterized. ...
382-484 4.50e-39

Domain of unknown function (DUF3496); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is about 110 amino acids in length.


Pssm-ID: 463425 [Multi-domain]  Cd Length: 109  Bit Score: 137.87  E-value: 4.50e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504  382 RTQMELRIKDLESEFSKMK-SQVDCNQIEMENYKQLYLAEVKIRKSLSNKLSKTDERLAEVKTKLLLERKQYRaSQYSMV 460
Cdd:pfam12001   1 RSQMELRIKDLESELSKMKtSQEDSNKIELEKYKQLYLEELKVRKSLSNKLNKTNERLAEVSTKLLVEKQQNR-SLLSTL 79
                          90       100       110
                  ....*....|....*....|....*....|
gi 225543504  461 DTRPALEPTCPRD------SNKFFIPRSFS 484
Cdd:pfam12001  80 TTRPVLESPCVGNlnnslvLNRNFIPRENL 109
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
70-428 6.67e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 6.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504    70 LEKLQTVENEVNGLRKKLaDAAREQLQQGQELcnvrftlkqEEEKRKNVVWVYDKMKEQLREKEDQYNKEVKmkqKLEIR 149
Cdd:TIGR02168  188 LDRLEDILNELERQLKSL-ERQAEKAERYKEL---------KAELRELELALLVLRLEELREELEELQEELK---EAEEE 254
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504   150 VRELDMDLKTVRHNLNTVLEERNCIERQLFQEQntriiqdEILANHLHKQKELKMAQEKISSQLQEAPDQHTQCTEKmrd 229
Cdd:TIGR02168  255 LEELTAELQELEEKLEELRLEVSELEEEIEELQ-------KELYALANEISRLEQQKQILRERLANLERQLEELEAQ--- 324
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504   230 cIQKLGLENHKLKETARKQAEKIEQLKKNLlsgvlsDDLTEKLESASAKYLHLYEQNQLLRRELLSMRtiqRKCEKLKKH 309
Cdd:TIGR02168  325 -LEELESKLDELAEELAELEEKLEELKEEL------ESLEAELEELEAELEELESRLEELEEQLETLR---SKVAQLELQ 394
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504   310 KKKLEQEVVSLRSHMK----RNMIECGQIEQYKWEIEEKTKQELVGKLKQVNLFL-QTQAAYEDKLEKLRQKQNAsvRTQ 384
Cdd:TIGR02168  395 IASLNNEIERLEARLErledRRERLQQEIEELLKKLEEAELKELQAELEELEEELeELQEELERLEEALEELREE--LEE 472
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 225543504   385 MELRIKDLESEFSKMKSQVDCNQIEMENYKQLYLAEVKIRKSLS 428
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQS 516
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
109-422 4.66e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 39.72  E-value: 4.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504  109 KQEEEKrknvvwvYDKM-KEQLREKEDQYNKEVKMKQKLE----IRVRELDMDLKTVRHNLNTVLEERNCIERQLFQE-- 181
Cdd:pfam17380 287 RQQQEK-------FEKMeQERLRQEKEEKAREVERRRKLEeaekARQAEMDRQAAIYAEQERMAMERERELERIRQEErk 359
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504  182 -QNTRIIQDEIlANHLHKQKELKMAQ-------EKISSQLQEAPDQHTQCTEKMRDCIQKLglenhKLKETARKQAEKIE 253
Cdd:pfam17380 360 rELERIRQEEI-AMEISRMRELERLQmerqqknERVRQELEAARKVKILEEERQRKIQQQK-----VEMEQIRAEQEEAR 433
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504  254 QLKknllsgvlsddlTEKLESASAKYLHLYEQNQLLRRELLSMRTIQRKCEKLKKHKKKLEQEVVSLRSHMKRNMIECGQ 333
Cdd:pfam17380 434 QRE------------VRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKEL 501
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504  334 IEQYKWEIEEKTKQELVGKlkqvNLFLQTQAAYEdklEKLRQKQNASVRTQMEL----RIKDLESEFSKMKSQVDCNQIE 409
Cdd:pfam17380 502 EERKQAMIEEERKRKLLEK----EMEERQKAIYE---EERRREAEEERRKQQEMeerrRIQEQMRKATEERSRLEAMERE 574
                         330
                  ....*....|...
gi 225543504  410 MENYKQLYLAEVK 422
Cdd:pfam17380 575 REMMRQIVESEKA 587
 
Name Accession Description Interval E-value
DUF3496 pfam12001
Domain of unknown function (DUF3496); This presumed domain is functionally uncharacterized. ...
382-484 4.50e-39

Domain of unknown function (DUF3496); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is about 110 amino acids in length.


Pssm-ID: 463425 [Multi-domain]  Cd Length: 109  Bit Score: 137.87  E-value: 4.50e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504  382 RTQMELRIKDLESEFSKMK-SQVDCNQIEMENYKQLYLAEVKIRKSLSNKLSKTDERLAEVKTKLLLERKQYRaSQYSMV 460
Cdd:pfam12001   1 RSQMELRIKDLESELSKMKtSQEDSNKIELEKYKQLYLEELKVRKSLSNKLNKTNERLAEVSTKLLVEKQQNR-SLLSTL 79
                          90       100       110
                  ....*....|....*....|....*....|
gi 225543504  461 DTRPALEPTCPRD------SNKFFIPRSFS 484
Cdd:pfam12001  80 TTRPVLESPCVGNlnnslvLNRNFIPRENL 109
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
70-428 6.67e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 6.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504    70 LEKLQTVENEVNGLRKKLaDAAREQLQQGQELcnvrftlkqEEEKRKNVVWVYDKMKEQLREKEDQYNKEVKmkqKLEIR 149
Cdd:TIGR02168  188 LDRLEDILNELERQLKSL-ERQAEKAERYKEL---------KAELRELELALLVLRLEELREELEELQEELK---EAEEE 254
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504   150 VRELDMDLKTVRHNLNTVLEERNCIERQLFQEQntriiqdEILANHLHKQKELKMAQEKISSQLQEAPDQHTQCTEKmrd 229
Cdd:TIGR02168  255 LEELTAELQELEEKLEELRLEVSELEEEIEELQ-------KELYALANEISRLEQQKQILRERLANLERQLEELEAQ--- 324
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504   230 cIQKLGLENHKLKETARKQAEKIEQLKKNLlsgvlsDDLTEKLESASAKYLHLYEQNQLLRRELLSMRtiqRKCEKLKKH 309
Cdd:TIGR02168  325 -LEELESKLDELAEELAELEEKLEELKEEL------ESLEAELEELEAELEELESRLEELEEQLETLR---SKVAQLELQ 394
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504   310 KKKLEQEVVSLRSHMK----RNMIECGQIEQYKWEIEEKTKQELVGKLKQVNLFL-QTQAAYEDKLEKLRQKQNAsvRTQ 384
Cdd:TIGR02168  395 IASLNNEIERLEARLErledRRERLQQEIEELLKKLEEAELKELQAELEELEEELeELQEELERLEEALEELREE--LEE 472
                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 225543504   385 MELRIKDLESEFSKMKSQVDCNQIEMENYKQLYLAEVKIRKSLS 428
Cdd:TIGR02168  473 AEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQS 516
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
48-257 3.09e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.51  E-value: 3.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504    48 IQNAIHSYKRLIQLKTGHCKVLLEKLQTVENEVNGLRKKLADAAREQLQQGQELCNVRFTLKQEEEKRKNVVWVYDKMKE 127
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504   128 QLREKEDQYNKEVKMKQKLEIRVRELDMDLKTVRHNLNTVLEERNCIERQLFQEQNTRIIQDEILANHLHKQKELKMAQE 207
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE 869
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 225543504   208 KISSQLQEAPDQHTQCTEKMRDCIQKLGLENHKLKETARKQAEKIEQLKK 257
Cdd:TIGR02168  870 ELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEE 919
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
77-376 6.86e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 42.35  E-value: 6.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504    77 ENEVNGLRKKLADAAREQLQQGQELCNVRFTLKQEEEKRKNVVWVYDKMKEQLREKEDQYNKEVKMKQKLEIRVRELDMD 156
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE 755
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504   157 LKTVRHNLNTVLEERNCIERQLF------QEQNTRIIQDEILANHLHKQKElkmAQEKISSQLQEAPDQHTQCTEKMRDC 230
Cdd:TIGR02168  756 LTELEAEIEELEERLEEAEEELAeaeaeiEELEAQIEQLKEELKALREALD---ELRAELTLLNEEAANLRERLESLERR 832
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504   231 IQKLGLENHKLKETARKQAEKIEQLKKNLLS-GVLSDDLTEKLESASAKYLHLYEQNQLLRRELLSMRTIQRKCEKLKKH 309
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEElEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSE 912
                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 225543504   310 KKKLEQEVVSLRSHMKRNMIEC-GQIEQYKWEIEEKTKQELVGKLKQVNLFLQTQAAYEDKLEKLRQK 376
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLeVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
70-404 9.16e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.98  E-value: 9.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504    70 LEKLQTVENEVNGLRKKLADAaREQLQQGQELcnvrftlkqEEEKRKNVVWVYDKMKEQLREKEDQYNKEV----KMKQK 145
Cdd:TIGR02169  186 IERLDLIIDEKRQQLERLRRE-REKAERYQAL---------LKEKREYEGYELLKEKEALERQKEAIERQLasleEELEK 255
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504   146 LEIRVRELDMDLKTVRHNLNTVLEErncIERQLFQEQNTriIQDEILanhlhkqkELKMAQEKISSQLQEAPDQhtqcTE 225
Cdd:TIGR02169  256 LTEEISELEKRLEEIEQLLEELNKK---IKDLGEEEQLR--VKEKIG--------ELEAEIASLERSIAEKERE----LE 318
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504   226 KMRDCIQKLGLENHKLKETARKQAEKIEQLKKNLlsgvlsDDLTEKLESASAKYLHLYEQ-------NQLLRRELLSMRt 298
Cdd:TIGR02169  319 DAEERLAKLEAEIDKLLAEIEELEREIEEERKRR------DKLTEEYAELKEELEDLRAEleevdkeFAETRDELKDYR- 391
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504   299 iqRKCEKLKKHKKKLEQEVVSLRSHMKRNMIECGQIEQYKWEIEEK------TKQELVGKLKQVNLFLQTQAA----YED 368
Cdd:TIGR02169  392 --EKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKineleeEKEDKALEIKKQEWKLEQLAAdlskYEQ 469
                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 225543504   369 KLEKLRQKQNasvrtQMELRIKDLESEFSKMKSQVD 404
Cdd:TIGR02169  470 ELYDLKEEYD-----RVEKELSKLQRELAEAEAQAR 500
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
109-422 4.66e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 39.72  E-value: 4.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504  109 KQEEEKrknvvwvYDKM-KEQLREKEDQYNKEVKMKQKLE----IRVRELDMDLKTVRHNLNTVLEERNCIERQLFQE-- 181
Cdd:pfam17380 287 RQQQEK-------FEKMeQERLRQEKEEKAREVERRRKLEeaekARQAEMDRQAAIYAEQERMAMERERELERIRQEErk 359
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504  182 -QNTRIIQDEIlANHLHKQKELKMAQ-------EKISSQLQEAPDQHTQCTEKMRDCIQKLglenhKLKETARKQAEKIE 253
Cdd:pfam17380 360 rELERIRQEEI-AMEISRMRELERLQmerqqknERVRQELEAARKVKILEEERQRKIQQQK-----VEMEQIRAEQEEAR 433
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504  254 QLKknllsgvlsddlTEKLESASAKYLHLYEQNQLLRRELLSMRTIQRKCEKLKKHKKKLEQEVVSLRSHMKRNMIECGQ 333
Cdd:pfam17380 434 QRE------------VRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKEL 501
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543504  334 IEQYKWEIEEKTKQELVGKlkqvNLFLQTQAAYEdklEKLRQKQNASVRTQMEL----RIKDLESEFSKMKSQVDCNQIE 409
Cdd:pfam17380 502 EERKQAMIEEERKRKLLEK----EMEERQKAIYE---EERRREAEEERRKQQEMeerrRIQEQMRKATEERSRLEAMERE 574
                         330
                  ....*....|...
gi 225543504  410 MENYKQLYLAEVK 422
Cdd:pfam17380 575 REMMRQIVESEKA 587
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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