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Conserved domains on  [gi|229892334|ref|NP_839975|]
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transmembrane epididymal protein 1A [Mus musculus]

Protein Classification

TMEM45 family protein( domain architecture ID 1388)

TMEM45 family protein is a DUF716 domain-containing protein; similar to Rattus norvegicus transmembrane epididymal protein 1

Gene Ontology:  GO:0016020

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF716 super family cl04775
Family of unknown function (DUF716); This family is equally distributed in both metazoa and ...
 145-246 2.33e-16

Family of unknown function (DUF716); This family is equally distributed in both metazoa and plants. Annotation associated with Swiss:Q9SLW7 suggest that it may be involved in response to viral attack in plants. However, no clear function has been assigned to this family.


The actual alignment was detected with superfamily member pfam04819:

Pssm-ID: 461443  Cd Length: 138  Bit Score: 74.18  E-value: 2.33e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892334  145 SHVKESSGVELQVHSLLILVVFLLMLVLTAELWAPEMFHLWMIETFLILIMGSWLIQAAFILFRPV-------------- 210
Cdd:pfam04819  21 FHSTDHSGLEGQYHLLLQLVIFLCLLSTLLEALLPKSFLADLVRSASILLQGLWFWQMGFMLYTPSfipggchdvcsggh 100

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 229892334  211 SGFPW--EDDDISDIMFVTTFFCWHVMINALCMLGIYG 246
Cdd:pfam04819 101 GGVKCdsEEADHRAKALANLQFSWHVAFVLVFVVVLYA 138
 
Name Accession Description Interval E-value
DUF716 pfam04819
Family of unknown function (DUF716); This family is equally distributed in both metazoa and ...
 145-246 2.33e-16

Family of unknown function (DUF716); This family is equally distributed in both metazoa and plants. Annotation associated with Swiss:Q9SLW7 suggest that it may be involved in response to viral attack in plants. However, no clear function has been assigned to this family.


Pssm-ID: 461443  Cd Length: 138  Bit Score: 74.18  E-value: 2.33e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892334  145 SHVKESSGVELQVHSLLILVVFLLMLVLTAELWAPEMFHLWMIETFLILIMGSWLIQAAFILFRPV-------------- 210
Cdd:pfam04819  21 FHSTDHSGLEGQYHLLLQLVIFLCLLSTLLEALLPKSFLADLVRSASILLQGLWFWQMGFMLYTPSfipggchdvcsggh 100

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 229892334  211 SGFPW--EDDDISDIMFVTTFFCWHVMINALCMLGIYG 246
Cdd:pfam04819 101 GGVKCdsEEADHRAKALANLQFSWHVAFVLVFVVVLYA 138
 
Name Accession Description Interval E-value
DUF716 pfam04819
Family of unknown function (DUF716); This family is equally distributed in both metazoa and ...
 145-246 2.33e-16

Family of unknown function (DUF716); This family is equally distributed in both metazoa and plants. Annotation associated with Swiss:Q9SLW7 suggest that it may be involved in response to viral attack in plants. However, no clear function has been assigned to this family.


Pssm-ID: 461443  Cd Length: 138  Bit Score: 74.18  E-value: 2.33e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892334  145 SHVKESSGVELQVHSLLILVVFLLMLVLTAELWAPEMFHLWMIETFLILIMGSWLIQAAFILFRPV-------------- 210
Cdd:pfam04819  21 FHSTDHSGLEGQYHLLLQLVIFLCLLSTLLEALLPKSFLADLVRSASILLQGLWFWQMGFMLYTPSfipggchdvcsggh 100

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 229892334  211 SGFPW--EDDDISDIMFVTTFFCWHVMINALCMLGIYG 246
Cdd:pfam04819 101 GGVKCdsEEADHRAKALANLQFSWHVAFVLVFVVVLYA 138
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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