NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|665394924|ref|NP_788730|]
View 

rootletin, isoform F [Drosophila melanogaster]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
110-330 5.31e-49

Ciliary rootlet component, centrosome cohesion;


:

Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 173.30  E-value: 5.31e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   110 RRRLDTYKQAQHNQANLVSRLQSKIQQYRQRCSDLEERMHETikptagvgpklTTGPTNQVLCSTSLTLGQSSlpcsssl 189
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEK-----------TSELEKTELLLRKLTLEPRL------- 62

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   190 dsppPSCSRDYVDDVlvtgggagaAELCRKLEEEHQRCEQIVAQNSALRQQLEESNRTNEALTNDLQKLTNDWASLRDEL 269
Cdd:pfam15035   63 ----QRLEREHSADL---------EEALIRLEEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREEL 129

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 665394924   270 LIKEDEFKEEEQAFKDYYNSEHNRLLKMWREVVAVKRSFKEMQTAMKAEVAKMGQEINCVG 330
Cdd:pfam15035  130 EQKESEWRKEEEAFNEYLSSEHSRLLSLWREVVAVRRQFTELKTATERDLSELKTEFSRTS 190
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 991-1779 6.95e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.06  E-value: 6.95e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   991 KRMQQALQALQTAKDDeIEKLQERLATLQAHLESLVQQHEEAL----IRAESEKQQALLIAHRDKQAVAErLEAVSRDLK 1066
Cdd:TIGR02168  172 ERRKETERKLERTREN-LDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELREE-LEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1067 TEQESLDRSRREANARDEKqraaIAQLKDEMVQMRTKEEEHKIKLEEC---IRKQELQLSSLREERESLCRVSEELKMEI 1143
Cdd:TIGR02168  250 EAEEELEELTAELQELEEK----LEELRLEVSELEEEIEELQKELYALaneISRLEQQKQILRERLANLERQLEELEAQL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1144 rlkeDRMESTNNELQDALRKSKEGegfIDSLRKELTDCRRQLadsnierdkysgsnKELRDHVKRVESAKREQARAIEEA 1223
Cdd:TIGR02168  326 ----EELESKLDELAEELAELEEK---LEELKEELESLEAEL--------------EELEAELEELESRLEELEEQLETL 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1224 LQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVefaqkdeggKELQCKLVAEVELKERAQQE 1303
Cdd:TIGR02168  385 RSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL---------KELQAELEELEEELEELQEE 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1304 LCQIKKQLSDLEANLCATRQELGRARCQNNQEEHRFHAREQELAQRLEEGRGrEKRLEDQKHNLEVCLADATQQI----- 1378
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEG-VKALLKNQSGLSGILGVLSELIsvdeg 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1379 --QELKARLGGAEGRI--RALDEQLSCVELHKRDTEQKLSSVVHTLRRIAGIQVDGSVNLSHrllspsrrfspSRSCGDY 1454
Cdd:TIGR02168  535 yeAAIEAALGGRLQAVvvENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKN-----------IEGFLGV 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1455 DNRSTSQCPDGPIDVDPDL----VRKGVRNLMHQVAQLERE------KDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQ 1524
Cdd:TIGR02168  604 AKDLVKFDPKLRKALSYLLggvlVVDDLDNALELAKKLRPGyrivtlDGDLVRPGGVITGGSAKTNSSILERRREIEELE 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1525 AMLRNLQEEKSNLETDRKMKISAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEK 1604
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1605 RQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKS 1684
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1685 AVSETQLRGEIKTLQKELSEQGHCSQANEDKLKLVQKSLQTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQ 1764
Cdd:TIGR02168  844 EEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREK 923

                          810
                   ....*....|....*
gi 665394924  1765 VTDLEVQRSALESQL 1779
Cdd:TIGR02168  924 LAQLELRLEGLEVRI 938
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 503-1314 1.81e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 99.36  E-value: 1.81e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   503 AVQAALHKYQLALHDMQVKFQNtsETLRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSELLQERESLQRGLDDIR 582
Cdd:TIGR02168  217 ELKAELRELELALLVLRLEELR--EELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   583 VQKQQSEMGRADINSAFENLSSDYEKMQLNCGKLQKRIDSMEEDKKAVELEIQRILKDKNITELNLRSEEDRSSRLREET 662
Cdd:TIGR02168  295 NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   663 ISLREELNRVSLNRDLLEQQRIESDNLINLLEKQKSDLEydldklllekcdlqekheklsnnscstsdelKSVQNCLQEA 742
Cdd:TIGR02168  375 EELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE-------------------------------DRRERLQQEI 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   743 QEERKKLriqsvdQCNEIGELKKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQDLacvtRDRGDIHNQLTAMCRK 822
Cdd:TIGR02168  424 EELLKKL------EEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQAL----DAAERELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   823 KEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVE-----EKQVVIDLHEKDTHRLNELLAALRSEKESLESVLFDTN 897
Cdd:TIGR02168  494 LERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISvdegyEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRV 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   898 TSLEATEERRSQLERDLQEALVREESlknhVARLQKELEQCQRKAQETKTQLLNAARAAEsdfnqkiaNLQACAEEAAK- 976
Cdd:TIGR02168  574 TFLPLDSIKGTEIQGNDREILKNIEG----FLGVAKDLVKFDPKLRKALSYLLGGVLVVD--------DLDNALELAKKl 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   977 RHGEEILQLRNAL-----------EKRMQQALqalqtAKDDEIEKLQERLATLQAHLESLvqqhEEALIRAESEkQQALL 1045
Cdd:TIGR02168  642 RPGYRIVTLDGDLvrpggvitggsAKTNSSIL-----ERRREIEELEEKIEELEEKIAEL----EKALAELRKE-LEELE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1046 IAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMV---QMRTKEEEHKIKLEECIRKQELQL 1122
Cdd:TIGR02168  712 EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEeleERLEEAEEELAEAEAEIEELEAQI 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1123 SSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKEL 1202
Cdd:TIGR02168  792 EQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEEL 871

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1203 RDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEG 1282
Cdd:TIGR02168  872 ESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL 951

                          810       820       830
                   ....*....|....*....|....*....|...
gi 665394924  1283 GKELQCKLVAEVELK-ERAQQELCQIKKQLSDL 1314
Cdd:TIGR02168  952 TLEEAEALENKIEDDeEEARRRLKRLENKIKEL 984
Gp58 super family cl26834
gp58-like protein; Sequences found in this family are derived from a number of bacteriophage ...
 336-604 1.43e-03

gp58-like protein; Sequences found in this family are derived from a number of bacteriophage and prophage proteins. They are similar to gp58, a minor structural protein of Lactococcus delbrueckii bacteriophage LL-H.


The actual alignment was detected with superfamily member pfam07902:

Pssm-ID: 369586 [Multi-domain]  Cd Length: 594  Bit Score: 43.79  E-value: 1.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   336 SNATVAFAVQQAKRAADDELKQSQRSNDELQNqlatLKVQYESARHEIMERDQRLLELMNQLKKLEDRCAQAESQAA--- 412
Cdd:pfam07902  123 KTEIVESAEGIATRISEDTDKKLALINETISG----IRREYQDADRQLSSSYQAGIEGLKATMASDKIGLQAEIQASaqg 198

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   413 LASRYSDEIERLNNSMREIAQAVVQDAENADREADAEVTggvmqhmhlTRDAASVVGGAGGAGSTAGGGGKSPRRNSTRA 492
Cdd:pfam07902  199 LSQRYDNEIRKLSAKITTTSSGTTEAYESKLDDLRAEFT---------RSNQGMRTELESKISGLQSTQQSTAYQISQEI 269

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   493 SQafAEGTISAVQAALHKYQLALHDMQVKFQNTSETLRTTKAQLETSEGTkqlLTTKMQQLTEKLDSSNSKlsellQERE 572
Cdd:pfam07902  270 SN--REGAVSRVQQDLDSYQRRLQDAEKNYSSLTQTVKGLQSTVSDPNSK---LESRITQLAGLIEQKVTR-----GDVE 339

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 665394924   573 SLQRGLDD-----IRVQKQQSEMGRADINSAFeNLSS 604
Cdd:pfam07902  340 SIIRQSGDsimlaIKAKLPQSKMSGSEIISAI-NLNG 375
 
Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
110-330 5.31e-49

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 173.30  E-value: 5.31e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   110 RRRLDTYKQAQHNQANLVSRLQSKIQQYRQRCSDLEERMHETikptagvgpklTTGPTNQVLCSTSLTLGQSSlpcsssl 189
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEK-----------TSELEKTELLLRKLTLEPRL------- 62

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   190 dsppPSCSRDYVDDVlvtgggagaAELCRKLEEEHQRCEQIVAQNSALRQQLEESNRTNEALTNDLQKLTNDWASLRDEL 269
Cdd:pfam15035   63 ----QRLEREHSADL---------EEALIRLEEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREEL 129

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 665394924   270 LIKEDEFKEEEQAFKDYYNSEHNRLLKMWREVVAVKRSFKEMQTAMKAEVAKMGQEINCVG 330
Cdd:pfam15035  130 EQKESEWRKEEEAFNEYLSSEHSRLLSLWREVVAVRRQFTELKTATERDLSELKTEFSRTS 190
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 991-1779 6.95e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.06  E-value: 6.95e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   991 KRMQQALQALQTAKDDeIEKLQERLATLQAHLESLVQQHEEAL----IRAESEKQQALLIAHRDKQAVAErLEAVSRDLK 1066
Cdd:TIGR02168  172 ERRKETERKLERTREN-LDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELREE-LEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1067 TEQESLDRSRREANARDEKqraaIAQLKDEMVQMRTKEEEHKIKLEEC---IRKQELQLSSLREERESLCRVSEELKMEI 1143
Cdd:TIGR02168  250 EAEEELEELTAELQELEEK----LEELRLEVSELEEEIEELQKELYALaneISRLEQQKQILRERLANLERQLEELEAQL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1144 rlkeDRMESTNNELQDALRKSKEGegfIDSLRKELTDCRRQLadsnierdkysgsnKELRDHVKRVESAKREQARAIEEA 1223
Cdd:TIGR02168  326 ----EELESKLDELAEELAELEEK---LEELKEELESLEAEL--------------EELEAELEELESRLEELEEQLETL 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1224 LQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVefaqkdeggKELQCKLVAEVELKERAQQE 1303
Cdd:TIGR02168  385 RSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL---------KELQAELEELEEELEELQEE 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1304 LCQIKKQLSDLEANLCATRQELGRARCQNNQEEHRFHAREQELAQRLEEGRGrEKRLEDQKHNLEVCLADATQQI----- 1378
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEG-VKALLKNQSGLSGILGVLSELIsvdeg 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1379 --QELKARLGGAEGRI--RALDEQLSCVELHKRDTEQKLSSVVHTLRRIAGIQVDGSVNLSHrllspsrrfspSRSCGDY 1454
Cdd:TIGR02168  535 yeAAIEAALGGRLQAVvvENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKN-----------IEGFLGV 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1455 DNRSTSQCPDGPIDVDPDL----VRKGVRNLMHQVAQLERE------KDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQ 1524
Cdd:TIGR02168  604 AKDLVKFDPKLRKALSYLLggvlVVDDLDNALELAKKLRPGyrivtlDGDLVRPGGVITGGSAKTNSSILERRREIEELE 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1525 AMLRNLQEEKSNLETDRKMKISAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEK 1604
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1605 RQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKS 1684
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1685 AVSETQLRGEIKTLQKELSEQGHCSQANEDKLKLVQKSLQTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQ 1764
Cdd:TIGR02168  844 EEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREK 923

                          810
                   ....*....|....*
gi 665394924  1765 VTDLEVQRSALESQL 1779
Cdd:TIGR02168  924 LAQLELRLEGLEVRI 938
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 503-1314 1.81e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 99.36  E-value: 1.81e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   503 AVQAALHKYQLALHDMQVKFQNtsETLRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSELLQERESLQRGLDDIR 582
Cdd:TIGR02168  217 ELKAELRELELALLVLRLEELR--EELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   583 VQKQQSEMGRADINSAFENLSSDYEKMQLNCGKLQKRIDSMEEDKKAVELEIQRILKDKNITELNLRSEEDRSSRLREET 662
Cdd:TIGR02168  295 NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   663 ISLREELNRVSLNRDLLEQQRIESDNLINLLEKQKSDLEydldklllekcdlqekheklsnnscstsdelKSVQNCLQEA 742
Cdd:TIGR02168  375 EELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE-------------------------------DRRERLQQEI 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   743 QEERKKLriqsvdQCNEIGELKKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQDLacvtRDRGDIHNQLTAMCRK 822
Cdd:TIGR02168  424 EELLKKL------EEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQAL----DAAERELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   823 KEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVE-----EKQVVIDLHEKDTHRLNELLAALRSEKESLESVLFDTN 897
Cdd:TIGR02168  494 LERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISvdegyEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRV 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   898 TSLEATEERRSQLERDLQEALVREESlknhVARLQKELEQCQRKAQETKTQLLNAARAAEsdfnqkiaNLQACAEEAAK- 976
Cdd:TIGR02168  574 TFLPLDSIKGTEIQGNDREILKNIEG----FLGVAKDLVKFDPKLRKALSYLLGGVLVVD--------DLDNALELAKKl 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   977 RHGEEILQLRNAL-----------EKRMQQALqalqtAKDDEIEKLQERLATLQAHLESLvqqhEEALIRAESEkQQALL 1045
Cdd:TIGR02168  642 RPGYRIVTLDGDLvrpggvitggsAKTNSSIL-----ERRREIEELEEKIEELEEKIAEL----EKALAELRKE-LEELE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1046 IAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMV---QMRTKEEEHKIKLEECIRKQELQL 1122
Cdd:TIGR02168  712 EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEeleERLEEAEEELAEAEAEIEELEAQI 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1123 SSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKEL 1202
Cdd:TIGR02168  792 EQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEEL 871

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1203 RDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEG 1282
Cdd:TIGR02168  872 ESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL 951

                          810       820       830
                   ....*....|....*....|....*....|...
gi 665394924  1283 GKELQCKLVAEVELK-ERAQQELCQIKKQLSDL 1314
Cdd:TIGR02168  952 TLEEAEALENKIEDDeEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 815-1395 3.70e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.00  E-value: 3.70e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  815 QLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLESvlf 894
Cdd:COG1196   226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ--- 302

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  895 dtntSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLLNAARAAESdfnqkianlqacAEEA 974
Cdd:COG1196   303 ----DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE------------AEEA 366

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  975 AKRHGEEILQLRNALEKRMQQALQALQTAKddEIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAHRDKQAV 1054
Cdd:COG1196   367 LLEAEAELAEAEEELEELAEELLEALRAAA--ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAL 444

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1055 AERLEAVSRdLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEehkiKLEECIRKQELQLSSLRE--ERESL 1132
Cdd:COG1196   445 EEAAEEEAE-LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL----LLLEAEADYEGFLEGVKAalLLAGL 519

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1133 CRVSEELKMEIRLKE-----DRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKELRDHVK 1207
Cdd:COG1196   520 RGLAGAVAVLIGVEAayeaaLEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGA 599

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1208 RVESAKREQARAIEEALQKISNLEdtknslenERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKELQ 1287
Cdd:COG1196   600 AVDLVASDLREADARYYVLGDTLL--------GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELL 671

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1288 CKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEHRFHAREQELAQRLEEGRGREKRLEDQKHNL 1367
Cdd:COG1196   672 AALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751

                         570       580
                  ....*....|....*....|....*...
gi 665394924 1368 EVCLADATQQIQELKARLGGAEGRIRAL 1395
Cdd:COG1196   752 ALEELPEPPDLEELERELERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 556-1152 1.86e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.60  E-value: 1.86e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  556 KLDSSNSKLSELLQERESLQRGLDDIRVQKQQSEMGRADINSAFENLSSDYEKMQLNCGKLQKRIDSMEEDKKAVELEIQ 635
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  636 RILKDKNITELNLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQRIESDNLINLLEKQKSDLEYDLDKLLLEKCDLQ 715
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  716 EKHEKLSNnscstsdELKSVQNCLQEAQEERKKLRiqsvdqcNEIGELKKELAILDKARLELETDNLSAGEKLKCLQLEK 795
Cdd:COG1196   393 RAAAELAA-------QLEELEEAEEALLERLERLE-------EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  796 EKILQDLACVTRDRgdihnqltamcRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLhekdtHRL 875
Cdd:COG1196   459 EALLELLAELLEEA-----------ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGL-----RGL 522

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  876 NELLAALRSEKESLESVLfdtntSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEqcQRKAQETKTQLLNAARA 955
Cdd:COG1196   523 AGAVAVLIGVEAAYEAAL-----EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLP--LDKIRARAALAAALARG 595

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  956 AESDFNQKIANLQACAEEAAKRHGEEILqLRNALEKRMQQALQALQTAKDDEIEKLQERlatlqahleSLVQQHEEALIR 1035
Cdd:COG1196   596 AIGAAVDLVASDLREADARYYVLGDTLL-GRTLVAARLEAALRRAVTLAGRLREVTLEG---------EGGSAGGSLTGG 665

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1036 AESEKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECI 1115
Cdd:COG1196   666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEE 745

                         570       580       590
                  ....*....|....*....|....*....|....*..
gi 665394924 1116 RKQELQLSSLREERESLcrvsEELKMEIRLKEDRMES 1152
Cdd:COG1196   746 ELLEEEALEELPEPPDL----EELERELERLEREIEA 778
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
536-1113 6.36e-14

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 77.80  E-value: 6.36e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  536 LETSEGTKQLLTTKMQQLTEKLdssnSKLSELLQERESLQRGLDDIRVQKQQSEmgraDINSAFENLSSDYEKMQLNCGK 615
Cdd:PRK03918  185 IKRTENIEELIKEKEKELEEVL----REINEISSELPELREELEKLEKEVKELE----ELKEEIEELEKELESLEGSKRK 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  616 LQKRIDSMEEDKKAVELEIQRIlkDKNITELN-LRSEEDRSSRLREETISLREELNRVSLNRDLLEQQRIESDNLINLLE 694
Cdd:PRK03918  257 LEEKIRELEERIEELKKEIEEL--EEKVKELKeLKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELE 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  695 KQKSDLEY---DLDKLLLEKCDLQEKHEKLsnnscstsDELKSVQNCLQEAQEERKklriqsvdqCNEIGELKKELAILD 771
Cdd:PRK03918  335 EKEERLEElkkKLKELEKRLEELEERHELY--------EEAKAKKEELERLKKRLT---------GLTPEKLEKELEELE 397

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  772 KARLELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGD--IHNQLTAMCRKKEALNE---ELMRTRQRLEQTTETNSR 846
Cdd:PRK03918  398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpVCGRELTEEHRKELLEEytaELKRIEKELKEIEEKERK 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  847 LNRNLEEMVKDVEEKQVVIdlhekdthRLNELLAALRSEKESLESV----LFDTNTSLEATEERRSQLE---RDLQEALV 919
Cdd:PRK03918  478 LRKELRELEKVLKKESELI--------KLKELAEQLKELEEKLKKYnleeLEKKAEEYEKLKEKLIKLKgeiKSLKKELE 549

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  920 REESLKNHVARLQKELEQCQRKAQETKTQLLNAARAAESDFNQKIANLqacaEEAAKRHgeeiLQLRNAlEKRMQQALQA 999
Cdd:PRK03918  550 KLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL----EPFYNEY----LELKDA-EKELEREEKE 620

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1000 LQTAKdDEIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAHRDKQ----AVAERLEAVSRDLKTEQESLDRS 1075
Cdd:PRK03918  621 LKKLE-EELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSrelaGLRAELEELEKRREEIKKTLEKL 699

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|
gi 665394924 1076 RREANARDEKQR--AAIAQLKDEMVQMRTKEEEHKIKLEE 1113
Cdd:PRK03918  700 KEELEEREKAKKelEKLEKALERVEELREKVKKYKALLKE 739
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 703-1380 6.37e-14

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 77.85  E-value: 6.37e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   703 DLDKLLLEKCDLQEKHEKLSNNScstsdeLKSVQNCLQEAQEERKKL----RIQSVDQCNEIGELKKELAILDKARL--- 775
Cdd:pfam15921   89 DLQRRLNESNELHEKQKFYLRQS------VIDLQTKLQEMQMERDAMadirRRESQSQEDLRNQLQNTVHELEAAKClke 162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   776 ELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGD----------------IHNQLTAMCRKKEALNEELMRTRQRL-- 837
Cdd:pfam15921  163 DMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEasgkkiyehdsmstmhFRSLGSAISKILRELDTEISYLKGRIfp 242

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   838 -EQTTETNSRLNRNLEEMVKDVEEKQV--VIDLHEKDTHRLNELLAALRSEKESLESVLfdtNTSLEATEERRSQLERDL 914
Cdd:pfam15921  243 vEDQLEALKSESQNKIELLLQQHQDRIeqLISEHEVEITGLTEKASSARSQANSIQSQL---EIIQEQARNQNSMYMRQL 319

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   915 QEalvreesLKNHVARLQKELEQCQR----KAQETKTQL------LNAARAAESDFNQKIANL----QACAEEAAKRHGE 980
Cdd:pfam15921  320 SD-------LESTVSQLRSELREAKRmyedKIEELEKQLvlanseLTEARTERDQFSQESGNLddqlQKLLADLHKREKE 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   981 eiLQLRNALEKRMQQ-------ALQALQTAKDD---EIEKLQERLATLQAHLESLVQQhEEALIRAESEKQQALLIAHRD 1050
Cdd:pfam15921  393 --LSLEKEQNKRLWDrdtgnsiTIDHLRRELDDrnmEVQRLEALLKAMKSECQGQMER-QMAAIQGKNESLEKVSSLTAQ 469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1051 KQAVAERLEAVSRDLKTEQESLDRSRREAN----ARDEKQRAaIAQLKDEMVQMRTKEEehkIKLEEC--IRKQELQLSS 1124
Cdd:pfam15921  470 LESTKEMLRKVVEELTAKKMTLESSERTVSdltaSLQEKERA-IEATNAEITKLRSRVD---LKLQELqhLKNEGDHLRN 545

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1125 LREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKELRD 1204
Cdd:pfam15921  546 VQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEA 625

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1205 HVKRVESAKREQARAIEEALQKISNLEDTKNSLENE----RTRLSTILKETE---NHFTKTTQDLNAT----KAQLQKAQ 1273
Cdd:pfam15921  626 RVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEvktsRNELNSLSEDYEvlkRNFRNKSEEMETTtnklKMQLKSAQ 705

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1274 VEFAQKDEGGKELQCKLVAEVELKERAQQELCQIKKQLSDLEANLcatrQELGRARCQNNQEEHRFHAREQELAQ----- 1348
Cdd:pfam15921  706 SELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKI----QFLEEAMTNANKEKHFLKEEKNKLSQelstv 781

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 665394924  1349 ---------RLEEGRGREKRLEDQKHNLEVCLADATQQIQE 1380
Cdd:pfam15921  782 ateknkmagELEVLRSQERRLKEKVANMEVALDKASLQFAE 822
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
811-1385 9.32e-14

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 77.00  E-value: 9.32e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  811 DIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSrlnrNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLE 890
Cdd:PRK02224  203 DLHERLNGLESELAELDEEIERYEEQREQARETRD----EADEVLEEHEERREELETLEAEIEDLRETIAETEREREELA 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  891 SVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQEtktqllnaARAAESDFNQKIANLQAC 970
Cdd:PRK02224  279 EEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEE--------CRVAAQAHNEEAESLRED 350

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  971 AEEAAKRhGEEILQLRNALEKRMQQALQALQTAK------DDEIEKLQERLATLQAHLESLVQQHEEAL-----IRAESE 1039
Cdd:PRK02224  351 ADDLEER-AEELREEAAELESELEEAREAVEDRReeieelEEEIEELRERFGDAPVDLGNAEDFLEELReerdeLREREA 429

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1040 KQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQraaIAQLKDEMVQMRTKEEEHKIKLE--ECIRK 1117
Cdd:PRK02224  430 ELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRER---VEELEAELEDLEEEVEEVEERLEraEDLVE 506

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1118 QELQLSSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERdkysG 1197
Cdd:PRK02224  507 AEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKL----A 582

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1198 SNKElrdhvkrvesaKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFA 1277
Cdd:PRK02224  583 ELKE-----------RIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEA 651

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1278 QKDeggkelqcklvaevelKERAQQELCQIKKQLSDLEANLCATRQELGrarcqnnqeehrfhAREQELaQRLEEGRGRE 1357
Cdd:PRK02224  652 RED----------------KERAEEYLEQVEEKLDELREERDDLQAEIG--------------AVENEL-EELEELRERR 700

                         570       580
                  ....*....|....*....|....*...
gi 665394924 1358 KRLEDQKHNLEVcLADATQQIQELKARL 1385
Cdd:PRK02224  701 EALENRVEALEA-LYDEAEELESMYGDL 727
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 814-1148 2.07e-08

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 59.37  E-value: 2.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   814 NQLTAMCRKKEALNEELMRTR-QRLEQttetnSRLNRNLEEMVKDVEEKQvviDLHEKDTHRLNEL--LAALRSEKESLE 890
Cdd:pfam17380  272 NQLLHIVQHQKAVSERQQQEKfEKMEQ-----ERLRQEKEEKAREVERRR---KLEEAEKARQAEMdrQAAIYAEQERMA 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   891 svlFDTNTSLE--ATEERRSQLERDLQEALVREESLKNHVARLQKELEQcqrkAQETKTQLLNAARaaesdfnqKIANLQ 968
Cdd:pfam17380  344 ---MERERELEriRQEERKRELERIRQEEIAMEISRMRELERLQMERQQ----KNERVRQELEAAR--------KVKILE 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   969 ACAEEAAKRHGEEILQLRNALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEE---ALIRAESEKQQALL 1045
Cdd:pfam17380  409 EERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEErkrKKLELEKEKRDRKR 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1046 IAHRDKQAVAERLEAVSRDLKTEQesldRSRREANARDEKQRAAIAqlkdEMVQMRTKEEEHK--IKLEECIRKQElQLS 1123
Cdd:pfam17380  489 AEEQRRKILEKELEERKQAMIEEE----RKRKLLEKEMEERQKAIY----EEERRREAEEERRkqQEMEERRRIQE-QMR 559

                          330       340
                   ....*....|....*....|....*
gi 665394924  1124 SLREERESLCRVSEELKMEIRLKED 1148
Cdd:pfam17380  560 KATEERSRLEAMEREREMMRQIVES 584
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 213-683 4.85e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.78  E-value: 4.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  213 AAELCRKLEEEHQRCEQIVAQNSALRQQLEESNRTNEALTNDLQKLTNDWASLRDELLIKEDEFKEEEQAFKDYYNSEHN 292
Cdd:COG1196   311 RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  293 RLLKMwREVVAVKRSFKEMQTAMKAEVAKMGQEINcvgkdingSNATVAFAVQQAKRAADDELKQSQRSNDELQNQLATL 372
Cdd:COG1196   391 ALRAA-AELAAQLEELEEAEEALLERLERLEEELE--------ELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  373 KVQYESARHEIMERDQRLLELMNQLKKLEDRCAQAESQAALASRYSDEIER--LNNSMREIAQAV--VQDAENADREADA 448
Cdd:COG1196   462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAalLLAGLRGLAGAVavLIGVEAAYEAALE 541

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  449 EVTGGVMQHMHLTRDAASVVGGAGGAGSTAGGGGKSPRRNSTRASQAFAEGTISAVQAALHKYQLALHDMQVKFQNTSET 528
Cdd:COG1196   542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  529 LRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSELLQERESLQRGLDDIRVQKQQSEMGRADINSAFENLSSDYEK 608
Cdd:COG1196   622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 665394924  609 MQLNCGKLQKRIDSMEEDKKAVELEIQRILKDKNITELNLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQR 683
Cdd:COG1196   702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 901-1162 1.92e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 46.75  E-value: 1.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  901 EATEERRSQLERDLQEALvreeslkNHVARLQKELEQCQRKAQETKTQLLNAARAAESdfNQKIANLQACAE------EA 974
Cdd:NF012221 1565 ERAEADRQRLEQEKQQQL-------AAISGSQSQLESTDQNALETNGQAQRDAILEES--RAVTKELTTLAQgldaldSQ 1635

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  975 AKRHGEEILQLRN----ALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALL-IAHR 1049
Cdd:NF012221 1636 ATYAGESGDQWRNpfagGLLDRVQEQLDDAKKISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQGEQNQANAEQdIDDA 1715

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1050 DKQAVAERLEAVSRDLKTEQEsldRSRREANARDEKQR----AAIAQLKDEMVQMRTKeeehKIKLEECIR--KQELQLS 1123
Cdd:NF012221 1716 KADAEKRKDDALAKQNEAQQA---ESDANAAANDAQSRgeqdASAAENKANQAQADAK----GAKQDESDKpnRQGAAGS 1788

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 665394924 1124 -------SLREERESLCRVSEELKMEI--RLKEDRMESTNNELQDALR 1162
Cdd:NF012221 1789 glsgkaySVEGVAEPGSHINPDSPAAAdgRFSEGLTEQEQEALEGATN 1836
Gp58 pfam07902
gp58-like protein; Sequences found in this family are derived from a number of bacteriophage ...
 336-604 1.43e-03

gp58-like protein; Sequences found in this family are derived from a number of bacteriophage and prophage proteins. They are similar to gp58, a minor structural protein of Lactococcus delbrueckii bacteriophage LL-H.


Pssm-ID: 369586 [Multi-domain]  Cd Length: 594  Bit Score: 43.79  E-value: 1.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   336 SNATVAFAVQQAKRAADDELKQSQRSNDELQNqlatLKVQYESARHEIMERDQRLLELMNQLKKLEDRCAQAESQAA--- 412
Cdd:pfam07902  123 KTEIVESAEGIATRISEDTDKKLALINETISG----IRREYQDADRQLSSSYQAGIEGLKATMASDKIGLQAEIQASaqg 198

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   413 LASRYSDEIERLNNSMREIAQAVVQDAENADREADAEVTggvmqhmhlTRDAASVVGGAGGAGSTAGGGGKSPRRNSTRA 492
Cdd:pfam07902  199 LSQRYDNEIRKLSAKITTTSSGTTEAYESKLDDLRAEFT---------RSNQGMRTELESKISGLQSTQQSTAYQISQEI 269

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   493 SQafAEGTISAVQAALHKYQLALHDMQVKFQNTSETLRTTKAQLETSEGTkqlLTTKMQQLTEKLDSSNSKlsellQERE 572
Cdd:pfam07902  270 SN--REGAVSRVQQDLDSYQRRLQDAEKNYSSLTQTVKGLQSTVSDPNSK---LESRITQLAGLIEQKVTR-----GDVE 339

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 665394924   573 SLQRGLDD-----IRVQKQQSEMGRADINSAFeNLSS 604
Cdd:pfam07902  340 SIIRQSGDsimlaIKAKLPQSKMSGSEIISAI-NLNG 375
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 218-609 5.26e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.97  E-value: 5.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   218 RKLEEEHQRCEQIVAQNSALRQQLEESNRTNEALTNDLQKLTNDWASLRDELLIKEDEFKEEEQafkdyynsEHNRLLKM 297
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA--------EVEQLEER 748

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   298 WREvvavkrsfkemqtaMKAEVAKMGQEINCVGKDINGSnatvafavQQAKRAADDELKQSQRSNDELQNQLATLKVQYE 377
Cdd:TIGR02168  749 IAQ--------------LSKELTELEAEIEELEERLEEA--------EEELAEAEAEIEELEAQIEQLKEELKALREALD 806

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   378 SARHEIMERDQRLLELMNQLKKLEDRcaqAESQAALASRYSDEIERLNNSMrEIAQAVVQDAENADREADAEVTggvmqh 457
Cdd:TIGR02168  807 ELRAELTLLNEEAANLRERLESLERR---IAATERRLEDLEEQIEELSEDI-ESLAAEIEELEELIEELESELE------ 876

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   458 mHLTRDAASVVGGAGGAGSTAGGGGKSPRRNSTRASQAFAEgtISAVQAALHKYQLALHDMQVKFQNTSETLRTT-KAQL 536
Cdd:TIGR02168  877 -ALLNERASLEEALALLRSELEELSEELRELESKRSELRRE--LEELREKLAQLELRLEGLEVRIDNLQERLSEEySLTL 953

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   537 ETSEGTKQLLTTKMQQLTEKLDSSNSKLSEL-------LQERESLQRGLDDIRVQKqqsemgrADINSAFENLSSDYEKM 609
Cdd:TIGR02168  954 EEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaIEEYEELKERYDFLTAQK-------EDLTEAKETLEEAIEEI 1026
antiphage_ZorA_2 NF033915
anti-phage ZorAB system protein ZorA; Proteins of this subfamily are putative H+ channel ...
 962-1131 6.04e-03

anti-phage ZorAB system protein ZorA; Proteins of this subfamily are putative H+ channel proteins, but it has been reported that they are also involved in anti-phage defense.


Pssm-ID: 411476 [Multi-domain]  Cd Length: 383  Bit Score: 41.29  E-value: 6.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  962 QKIANLQACAEEA----AKRHGEEILQLRNALEKRMQQAL-QALQTAKDDEIEKL-QERLATLQAHLESLVQQHEEALIR 1035
Cdd:NF033915  209 VHIAEYSKESKEAlqelHERIGDRLQESLNGMSEAMQTALtDALNNIMAPAIQTLvSTTSQQSTQVLESLVGNFMDGMTS 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1036 AESEKQQALliahrdKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECI 1115
Cdd:NF033915  289 AGREQGLQM------QQAAADVNAAVSGMSERLNQLFNSLSEQQGRQMERAQQQSSTFETQLQRLSGSANERQAQLEQRF 362

                         170
                  ....*....|....*.
gi 665394924 1116 RKQELQLSSLREERES 1131
Cdd:NF033915  363 EELMSGLTEQLQTQLG 378
 
Name Accession Description Interval E-value
Rootletin pfam15035
Ciliary rootlet component, centrosome cohesion;
110-330 5.31e-49

Ciliary rootlet component, centrosome cohesion;


Pssm-ID: 464459 [Multi-domain]  Cd Length: 190  Bit Score: 173.30  E-value: 5.31e-49
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   110 RRRLDTYKQAQHNQANLVSRLQSKIQQYRQRCSDLEERMHETikptagvgpklTTGPTNQVLCSTSLTLGQSSlpcsssl 189
Cdd:pfam15035    1 RRKLQAYQEAQQRQAQLVQKLQAKVLQYKKRCSELEQQLLEK-----------TSELEKTELLLRKLTLEPRL------- 62

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   190 dsppPSCSRDYVDDVlvtgggagaAELCRKLEEEHQRCEQIVAQNSALRQQLEESNRTNEALTNDLQKLTNDWASLRDEL 269
Cdd:pfam15035   63 ----QRLEREHSADL---------EEALIRLEEERQRSESLSQVNSLLREQLEQASRANEALREDLQKLTNDWERAREEL 129

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 665394924   270 LIKEDEFKEEEQAFKDYYNSEHNRLLKMWREVVAVKRSFKEMQTAMKAEVAKMGQEINCVG 330
Cdd:pfam15035  130 EQKESEWRKEEEAFNEYLSSEHSRLLSLWREVVAVRRQFTELKTATERDLSELKTEFSRTS 190
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 991-1779 6.95e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.06  E-value: 6.95e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   991 KRMQQALQALQTAKDDeIEKLQERLATLQAHLESLVQQHEEAL----IRAESEKQQALLIAHRDKQAVAErLEAVSRDLK 1066
Cdd:TIGR02168  172 ERRKETERKLERTREN-LDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELREE-LEELQEELK 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1067 TEQESLDRSRREANARDEKqraaIAQLKDEMVQMRTKEEEHKIKLEEC---IRKQELQLSSLREERESLCRVSEELKMEI 1143
Cdd:TIGR02168  250 EAEEELEELTAELQELEEK----LEELRLEVSELEEEIEELQKELYALaneISRLEQQKQILRERLANLERQLEELEAQL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1144 rlkeDRMESTNNELQDALRKSKEGegfIDSLRKELTDCRRQLadsnierdkysgsnKELRDHVKRVESAKREQARAIEEA 1223
Cdd:TIGR02168  326 ----EELESKLDELAEELAELEEK---LEELKEELESLEAEL--------------EELEAELEELESRLEELEEQLETL 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1224 LQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVefaqkdeggKELQCKLVAEVELKERAQQE 1303
Cdd:TIGR02168  385 RSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEL---------KELQAELEELEEELEELQEE 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1304 LCQIKKQLSDLEANLCATRQELGRARCQNNQEEHRFHAREQELAQRLEEGRGrEKRLEDQKHNLEVCLADATQQI----- 1378
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEG-VKALLKNQSGLSGILGVLSELIsvdeg 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1379 --QELKARLGGAEGRI--RALDEQLSCVELHKRDTEQKLSSVVHTLRRIAGIQVDGSVNLSHrllspsrrfspSRSCGDY 1454
Cdd:TIGR02168  535 yeAAIEAALGGRLQAVvvENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKN-----------IEGFLGV 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1455 DNRSTSQCPDGPIDVDPDL----VRKGVRNLMHQVAQLERE------KDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQ 1524
Cdd:TIGR02168  604 AKDLVKFDPKLRKALSYLLggvlVVDDLDNALELAKKLRPGyrivtlDGDLVRPGGVITGGSAKTNSSILERRREIEELE 683

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1525 AMLRNLQEEKSNLETDRKMKISAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEK 1604
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1605 RQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKS 1684
Cdd:TIGR02168  764 EELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDL 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1685 AVSETQLRGEIKTLQKELSEQGHCSQANEDKLKLVQKSLQTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQ 1764
Cdd:TIGR02168  844 EEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREK 923

                          810
                   ....*....|....*
gi 665394924  1765 VTDLEVQRSALESQL 1779
Cdd:TIGR02168  924 LAQLELRLEGLEVRI 938
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 503-1314 1.81e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 99.36  E-value: 1.81e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   503 AVQAALHKYQLALHDMQVKFQNtsETLRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSELLQERESLQRGLDDIR 582
Cdd:TIGR02168  217 ELKAELRELELALLVLRLEELR--EELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   583 VQKQQSEMGRADINSAFENLSSDYEKMQLNCGKLQKRIDSMEEDKKAVELEIQRILKDKNITELNLRSEEDRSSRLREET 662
Cdd:TIGR02168  295 NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   663 ISLREELNRVSLNRDLLEQQRIESDNLINLLEKQKSDLEydldklllekcdlqekheklsnnscstsdelKSVQNCLQEA 742
Cdd:TIGR02168  375 EELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE-------------------------------DRRERLQQEI 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   743 QEERKKLriqsvdQCNEIGELKKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQDLacvtRDRGDIHNQLTAMCRK 822
Cdd:TIGR02168  424 EELLKKL------EEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQAL----DAAERELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   823 KEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVE-----EKQVVIDLHEKDTHRLNELLAALRSEKESLESVLFDTN 897
Cdd:TIGR02168  494 LERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISvdegyEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRV 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   898 TSLEATEERRSQLERDLQEALVREESlknhVARLQKELEQCQRKAQETKTQLLNAARAAEsdfnqkiaNLQACAEEAAK- 976
Cdd:TIGR02168  574 TFLPLDSIKGTEIQGNDREILKNIEG----FLGVAKDLVKFDPKLRKALSYLLGGVLVVD--------DLDNALELAKKl 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   977 RHGEEILQLRNAL-----------EKRMQQALqalqtAKDDEIEKLQERLATLQAHLESLvqqhEEALIRAESEkQQALL 1045
Cdd:TIGR02168  642 RPGYRIVTLDGDLvrpggvitggsAKTNSSIL-----ERRREIEELEEKIEELEEKIAEL----EKALAELRKE-LEELE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1046 IAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMV---QMRTKEEEHKIKLEECIRKQELQL 1122
Cdd:TIGR02168  712 EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEeleERLEEAEEELAEAEAEIEELEAQI 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1123 SSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKEL 1202
Cdd:TIGR02168  792 EQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEEL 871

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1203 RDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEG 1282
Cdd:TIGR02168  872 ESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL 951

                          810       820       830
                   ....*....|....*....|....*....|...
gi 665394924  1283 GKELQCKLVAEVELK-ERAQQELCQIKKQLSDL 1314
Cdd:TIGR02168  952 TLEEAEALENKIEDDeEEARRRLKRLENKIKEL 984
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1007-1777 9.25e-20

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 97.06  E-value: 9.25e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1007 EIEKLQERLATLQAHLESLVQQHEealiRAESEKQQALliahRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQ 1086
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLE----RLRREREKAE----RYQALLKEKREYEGYELLKEKEALERQKEAIERQLASL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1087 RAAIAQLKDEMVQMRTKEEEHKIKLEECIRKQELQLSslrEERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKE 1166
Cdd:TIGR02169  250 EEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE---EEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAK 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1167 GEGFIDSLRKELTDCRRQLADSNIERDK----YSGSNKELRDHVKRVESAKREQARAIEE---ALQKISNLEDTKNSLEN 1239
Cdd:TIGR02169  327 LEAEIDKLLAEIEELEREIEEERKRRDKlteeYAELKEELEDLRAELEEVDKEFAETRDElkdYREKLEKLKREINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1240 ERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKELQCKLVAEVELKERAQQELCQIKKQLSDLEANLC 1319
Cdd:TIGR02169  407 ELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELS 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1320 ATRQELGRARCQNNQEEHR---FHAREQELAQRLEEGRGREKRL----EDQKHNLEVCL------------ADATQQIQE 1380
Cdd:TIGR02169  487 KLQRELAEAEAQARASEERvrgGRAVEEVLKASIQGVHGTVAQLgsvgERYATAIEVAAgnrlnnvvveddAVAKEAIEL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1381 LKARLGGaegriraldeQLSCVELHKRDTEQKLSSVVHTlrriagiqvDGSVNLSHRLLSPSRRFSPS-----RSCGDYD 1455
Cdd:TIGR02169  567 LKRRKAG----------RATFLPLNKMRDERRDLSILSE---------DGVIGFAVDLVEFDPKYEPAfkyvfGDTLVVE 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1456 NRSTSQCPDGPI---DVDPDLVRKG-----------------------VRNLMHQVAQLEREKDDYKSQLGAAKKQLQDA 1509
Cdd:TIGR02169  628 DIEAARRLMGKYrmvTLEGELFEKSgamtggsraprggilfsrsepaeLQRLRERLEGLKRELSSLQSELRRIENRLDEL 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1510 ADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQ---- 1585
Cdd:TIGR02169  708 SQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDlear 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1586 -NEERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLE 1664
Cdd:TIGR02169  788 lSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELE 867

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1665 DRCTALKSTVDQLKERLQKsavsetqLRGEIKTLQKELSEQGHCSQANEDKLKLVQKSLQTAENEKRILTERLDSAQTNL 1744
Cdd:TIGR02169  868 EELEELEAALRDLESRLGD-------LKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPK 940

                          810       820       830
                   ....*....|....*....|....*....|...
gi 665394924  1745 NELRRSQQAQLDGNQrLQEQVTDLEVQRSALES 1777
Cdd:TIGR02169  941 GEDEEIPEEELSLED-VQAELQRVEEEIRALEP 972
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 730-1400 1.59e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.28  E-value: 1.59e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   730 DELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQDLACVTRDR 809
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   810 GDIHNQLTAMCRKKEALNEELMRTRQRLEQTT-------ETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAAL 882
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKeelesleAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   883 RSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVRE------------ESLKNHVARLQKELEQcQRKAQETKTQLL 950
Cdd:TIGR02168  399 NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKElqaeleeleeelEELQEELERLEEALEE-LREELEEAEQAL 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   951 NAARAAESDFNQKIANLQACAEEAAKRHGE--EILQLRNALEKRMQQALQALQTAKDDEIEKLqerlATLQAHLESLVQQ 1028
Cdd:TIGR02168  478 DAAERELAQLQARLDSLERLQENLEGFSEGvkALLKNQSGLSGILGVLSELISVDEGYEAAIE----AALGGRLQAVVVE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1029 HEEALIRA-----ESEKQQALLIAHRDkqAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMV----- 1098
Cdd:TIGR02168  554 NLNAAKKAiaflkQNELGRVTFLPLDS--IKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLvvddl 631

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1099 ------QMRTKEEEHKIKLE-ECIRKQELQLSSLREERES-LCRVSE--ELKMEIRLKEDRMESTNNELQDALRKSKEGE 1168
Cdd:TIGR02168  632 dnalelAKKLRPGYRIVTLDgDLVRPGGVITGGSAKTNSSiLERRREieELEEKIEELEEKIAELEKALAELRKELEELE 711

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1169 GFIDSLRKELTDCRRQLADSNIERDKYSGSNKELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTIL 1248
Cdd:TIGR02168  712 EELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQI 791

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1249 KETENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKELQCKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQELGRA 1328
Cdd:TIGR02168  792 EQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEEL 871

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 665394924  1329 RCQNNQEEHRFHAREQELAQ---RLEEGRGREKRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDEQLS 1400
Cdd:TIGR02168  872 ESELEALLNERASLEEALALlrsELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS 946
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 821-1747 2.36e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.51  E-value: 2.36e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   821 RKKEALNeelmrtrqRLEQTTETNSRLNRNLEEMVKDVE--EKQVvidlhekdthRLNELLAALRSEKESLESVLfdTNT 898
Cdd:TIGR02168  173 RRKETER--------KLERTRENLDRLEDILNELERQLKslERQA----------EKAERYKELKAELRELELAL--LVL 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   899 SLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQlLNAARAAESDFNQKIANLqacaEEAAKRH 978
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE-IEELQKELYALANEISRL----EQQKQIL 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   979 GEEILQLRNALEKRMQQALQALQtakddEIEKLQERLATLQAHLESLVQQHE--EALIRAESEKQQALLIAHRDKQAVAE 1056
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEELES-----KLDELAEELAELEEKLEELKEELEslEAELEELEAELEELESRLEELEEQLE 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1057 RLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIK-LEECIRKQELQLSSLREERESLCRV 1135
Cdd:TIGR02168  383 TLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKeLQAELEELEEELEELQEELERLEEA 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1136 SEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKeLTDCRRQLADSNIERDKYSGSNKELRDHVKRVESAKre 1215
Cdd:TIGR02168  463 LEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG-FSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAI-- 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1216 qARAIEEALQKI--SNLEDTK---NSLENERTRLSTILKETenhftkttqdlNATKAQLQKAQVEFAQKDEGGKELQCKL 1290
Cdd:TIGR02168  540 -EAALGGRLQAVvvENLNAAKkaiAFLKQNELGRVTFLPLD-----------SIKGTEIQGNDREILKNIEGFLGVAKDL 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1291 VAEVElkeraqqelcQIKKQLSDLEAN-LCATRQELGRARCQNNQEEHRFHAREQELAQR-----LEEGRGREKRLEDQK 1364
Cdd:TIGR02168  608 VKFDP----------KLRKALSYLLGGvLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPggvitGGSAKTNSSILERRR 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1365 H--NLEVCLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTEQKLSSVVHTLRRIagiqvdgsvnlshrllsps 1442
Cdd:TIGR02168  678 EieELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL------------------- 738

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1443 rrfspsrscgdydnrstsqcpdgpidvdpdlvRKGVRNLMHQVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGK 1522
Cdd:TIGR02168  739 --------------------------------EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEE 786

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1523 LQAMLRNLQEEKSNLEtdrkmkiSAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDN 1602
Cdd:TIGR02168  787 LEAQIEQLKEELKALR-------EALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA 859

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1603 EKRQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCSIRQMaerlenqNRALTQLEDRCTALKSTVDQLKERLQ 1682
Cdd:TIGR02168  860 EIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELREL-------ESKRSELRRELEELREKLAQLELRLE 932

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 665394924  1683 KsavsetqLRGEIKTLQKELSEQGhcsqanEDKLKLVQKSLQTAENEKRILTERLDSAQTNLNEL 1747
Cdd:TIGR02168  933 G-------LEVRIDNLQERLSEEY------SLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 815-1395 3.70e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.00  E-value: 3.70e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  815 QLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLESvlf 894
Cdd:COG1196   226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ--- 302

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  895 dtntSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLLNAARAAESdfnqkianlqacAEEA 974
Cdd:COG1196   303 ----DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE------------AEEA 366

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  975 AKRHGEEILQLRNALEKRMQQALQALQTAKddEIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAHRDKQAV 1054
Cdd:COG1196   367 LLEAEAELAEAEEELEELAEELLEALRAAA--ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEAL 444

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1055 AERLEAVSRdLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEehkiKLEECIRKQELQLSSLRE--ERESL 1132
Cdd:COG1196   445 EEAAEEEAE-LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL----LLLEAEADYEGFLEGVKAalLLAGL 519

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1133 CRVSEELKMEIRLKE-----DRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKELRDHVK 1207
Cdd:COG1196   520 RGLAGAVAVLIGVEAayeaaLEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGA 599

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1208 RVESAKREQARAIEEALQKISNLEdtknslenERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKELQ 1287
Cdd:COG1196   600 AVDLVASDLREADARYYVLGDTLL--------GRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELL 671

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1288 CKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEHRFHAREQELAQRLEEGRGREKRLEDQKHNL 1367
Cdd:COG1196   672 AALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751

                         570       580
                  ....*....|....*....|....*...
gi 665394924 1368 EVCLADATQQIQELKARLGGAEGRIRAL 1395
Cdd:COG1196   752 ALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1125-1832 8.99e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.58  E-value: 8.99e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1125 LREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKELRD 1204
Cdd:TIGR02168  195 LNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRL 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1205 HVKRVESAKREQARAIEEALQKISNLEDTK-------NSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFA 1277
Cdd:TIGR02168  275 EVSELEEEIEELQKELYALANEISRLEQQKqilrerlANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1278 QKDEGGKELQCKL--------------------VAEVELKERAQQ-ELCQIKKQLSDLEANLCATRQEL-GRARCQNNQE 1335
Cdd:TIGR02168  355 SLEAELEELEAELeelesrleeleeqletlrskVAQLELQIASLNnEIERLEARLERLEDRRERLQQEIeELLKKLEEAE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1336 EHRFHAREQELAQRLEEGRGREKRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDEQLScvelHKRDTEQKLSS 1415
Cdd:TIGR02168  435 LKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE----NLEGFSEGVKA 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1416 VVHTLRRIAG--------IQVDG------SVNLSHRLLSP-SRRFSPSRSCGDYDNRST---------SQCPDGPIDVDP 1471
Cdd:TIGR02168  511 LLKNQSGLSGilgvlselISVDEgyeaaiEAALGGRLQAVvVENLNAAKKAIAFLKQNElgrvtflplDSIKGTEIQGND 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1472 DLVRKGVRNLMHQVAQLEREKDDYKSQLGAAKkqlqdaadQQLRCDAKLGKLQAMLRNLQEEKSNLETD----------- 1540
Cdd:TIGR02168  591 REILKNIEGFLGVAKDLVKFDPKLRKALSYLL--------GGVLVVDDLDNALELAKKLRPGYRIVTLDgdlvrpggvit 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1541 --RKMKISAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVEGRA 1618
Cdd:TIGR02168  663 ggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEV 742

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1619 SKLELQrvamegdLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTL 1698
Cdd:TIGR02168  743 EQLEER-------IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1699 QKELSEQGHCSQANEDKLKLVQKSLQTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQ 1778
Cdd:TIGR02168  816 NEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE 895

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....
gi 665394924  1779 LRiakwNQESGGDKDLTNGNGGGNGEEELSRQLKSSQREKSELRSKLQTLQDKV 1832
Cdd:TIGR02168  896 LE----ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 991-1629 3.75e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 91.54  E-value: 3.75e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  991 KRMQQALQALQTAKDDeIEKLQERLATLQAHLESLVQQHEEAL----IRAESEKQQALLIAHRDK--QAVAERLEAVSRD 1064
Cdd:COG1196   172 ERKEEAERKLEATEEN-LERLEDILGELERQLEPLERQAEKAEryreLKEELKELEAELLLLKLRelEAELEELEAELEE 250

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1065 LKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECIRKQELQLSSLREERESLcrvsEELKMEIR 1144
Cdd:COG1196   251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERL----EELEEELA 326

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1145 LKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDkysgsnkELRDHVKRVESAKREQARAIEEAL 1224
Cdd:COG1196   327 ELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA-------EAEEELEELAEELLEALRAAAELA 399

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1225 QKISNLEDTKNSLENERTRLstilketenhftkttqdlNATKAQLQKAQVEFAQKDEggkELQCKLVAEVELKERAQQEL 1304
Cdd:COG1196   400 AQLEELEEAEEALLERLERL------------------EEELEELEEALAELEEEEE---EEEEALEEAAEEEAELEEEE 458

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1305 CQIKKQLSDLEANLCATRQELGRARCQNNQEEHRFHAREQELAQRLEEGRG-REKRLEDQKHNLEVCLADATQQIQE--- 1380
Cdd:COG1196   459 EALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvKAALLLAGLRGLAGAVAVLIGVEAAyea 538

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1381 -LKARLGGAEGRIRALDEQ--LSCVELHKRDTEQKLssvvhTLRRIAGIQVDGSVNLSHRLLSPSRRFSPSRSCGDYDNR 1457
Cdd:COG1196   539 aLEAALAAALQNIVVEDDEvaAAAIEYLKAAKAGRA-----TFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADA 613

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1458 STSQcpdgpiDVDPDLVRKGVRNLMHQVAQLEREKD-DYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSN 1536
Cdd:COG1196   614 RYYV------LGDTLLGRTLVAARLEAALRRAVTLAgRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAER 687

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1537 LETDRKMKISAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVEG 1616
Cdd:COG1196   688 LAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELER 767

                         650
                  ....*....|...
gi 665394924 1617 RASKLELQRVAME 1629
Cdd:COG1196   768 ELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 731-1320 2.51e-17

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 88.84  E-value: 2.51e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  731 ELKSVQNCLQEAQEERKKLRiqsvdqcNEIGELKKELAILDKARLELEtdnlsagEKLKCLQLEKEKILQDLACVTRDRG 810
Cdd:COG1196   233 KLRELEAELEELEAELEELE-------AELEELEAELAELEAELEELR-------LELEELELELEEAQAEEYELLAELA 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  811 DIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLE 890
Cdd:COG1196   299 RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  891 SVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQcQRKAQETKTQLLNAARAAESDFNQKIANLQAc 970
Cdd:COG1196   379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE-LEEALAELEEEEEEEEEALEEAAEEEAELEE- 456

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  971 AEEAAKRHGEEILQLRNALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAHRD 1050
Cdd:COG1196   457 EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAY 536

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1051 KQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLkdemVQMRTKEEEHKIKLEECIRKQELQLSSLREERE 1130
Cdd:COG1196   537 EAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPL----DKIRARAALAAALARGAIGAAVDLVASDLREAD 612

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1131 SLCRVSEELKMEIRLKEDRMEStnnelqdalrkskeGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKELRDHVKRVE 1210
Cdd:COG1196   613 ARYYVLGDTLLGRTLVAARLEA--------------ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAE 678

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1211 SAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEggkELQCKL 1290
Cdd:COG1196   679 AELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLE---EEALEE 755

                         570       580       590
                  ....*....|....*....|....*....|.
gi 665394924 1291 VAEVELKERAQQELCQIKKQLSDLEA-NLCA 1320
Cdd:COG1196   756 LPEPPDLEELERELERLEREIEALGPvNLLA 786
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 364-1186 7.80e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 87.42  E-value: 7.80e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   364 ELQNQLATLKVQYESARHEIMERDQ-RLLELMNQLKKLEDRCAQAESQAALASRYSDEIERLNNSMREiAQAVVQDAENA 442
Cdd:TIGR02168  197 ELERQLKSLERQAEKAERYKELKAElRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQE-LEEKLEELRLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   443 DREADAEVTggvmqhmhlTRDAASVVGGAGGAGSTAGGGGKSPRRNSTRASQAFAEGTISAVQAALHKYQLALHDMQVKF 522
Cdd:TIGR02168  276 VSELEEEIE---------ELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKL 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   523 QNTSETLRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSELLQERESLQRGLDDIRVQKQQSEmgradinSAFENL 602
Cdd:TIGR02168  347 EELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE-------DRRERL 419

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   603 SSDYEKMQLNCGKLQKRIDSMEEDKKAVELEIQRilKDKNITELNLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQ 682
Cdd:TIGR02168  420 QQEIEELLKKLEEAELKELQAELEELEEELEELQ--EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   683 RIESDNL---INLLEKQKSDLEYDLDkLLLEKCDLQEKHEK---------LSNNSCSTSDELKSVQNCLQEAQEERKKLR 750
Cdd:TIGR02168  498 QENLEGFsegVKALLKNQSGLSGILG-VLSELISVDEGYEAaieaalggrLQAVVVENLNAAKKAIAFLKQNELGRVTFL 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   751 IQSVDQCNEIGELKKELAILDKARLELETDNLSAGEKLKCL---QLEKEKILQDLACVTRDRGDIHNQLTAMCRKKEALN 827
Cdd:TIGR02168  577 PLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAlsyLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVR 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   828 EELMRTRQRLEQTtetNSRLNRNLEemVKDVEEKqvvIDLHEKDTHRLNELLAALRSEKESLESVLFDTNTSLEATEERR 907
Cdd:TIGR02168  657 PGGVITGGSAKTN---SSILERRRE--IEELEEK---IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQI 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   908 SQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLlNAARAAESDFNQKIANLQACAEEaakrhgeeiLQLRN 987
Cdd:TIGR02168  729 SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERL-EEAEEELAEAEAEIEELEAQIEQ---------LKEEL 798

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   988 ALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQalliahrdkqavAERLEAVSRDLKT 1067
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSED------------IESLAAEIEELEE 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1068 EQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEhkikLEECIRKQELQLSSLREERESLCRVSEELKMEI-RLK 1146
Cdd:TIGR02168  867 LIEELESELEALLNERASLEEALALLRSELEELSEELRE----LESKRSELRRELEELREKLAQLELRLEGLEVRIdNLQ 942

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 665394924  1147 EDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLA 1186
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1483-2029 1.09e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 86.91  E-value: 1.09e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1483 HQVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEEKLKHRNDEC 1562
Cdd:COG1196   232 LKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERR 311

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1563 QMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEK 1642
Cdd:COG1196   312 RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA 391

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1643 DCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEQghcsQANEDKLKLVQKS 1722
Cdd:COG1196   392 LRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL----EEEEEALLELLAE 467

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1723 LQTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQLRIAKWnqeSGGDKDLTNGNGGGN 1802
Cdd:COG1196   468 LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVL---IGVEAAYEAALEAAL 544

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1803 GEEELSRQLKSSQREKSELRSKLQTLQDKVKQLECDRKSKFSGGNAYDRAEKSNSFYGGAAESGEFDSNRYDVGGGNAGG 1882
Cdd:COG1196   545 AAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLG 624

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1883 GSFNCGLDHSVIEQ-ETRDLRLKVRRLETLLAEKESELARCKARMNDSAKCHDGLDGDRYRSAQMHAEKLLDAREQSHRQ 1961
Cdd:COG1196   625 RTLVAARLEAALRRaVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEE 704

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 665394924 1962 QVLRLENQISMLREQLAQEAKRRQQYILRSSKANREMQHLRSTLGDSLRNVSQHPVDPHLLESESRRL 2029
Cdd:COG1196   705 EERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 846-1648 1.20e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 86.65  E-value: 1.20e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   846 RLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVREESLK 925
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   926 NHVARLQKELEQCQRKAQETKTQLlnaaraaeSDFNQKIANLQACAEEAAKRHgEEILQLRNALEKRMQQALQALQTAKD 1005
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEEL--------AELEEKLEELKEELESLEAEL-EELEAELEELESRLEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1006 DEIEkLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEK 1085
Cdd:TIGR02168  387 KVAQ-LELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1086 QRAAIAQLKDEMVQMRTKEEEHKIKLEECIRKQElQLSSLREERESLCRVSEELKMEIRLKEDRMESTNN---------- 1155
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLERLQE-NLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGyeaaieaalg 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1156 -ELQDALRKSKEG-EGFIDSLRKELTDCRRQLADSNIERDKYSGSNKELR---DHVKRVESAKREQARAIEEALQKISNL 1230
Cdd:TIGR02168  545 gRLQAVVVENLNAaKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILkniEGFLGVAKDLVKFDPKLRKALSYLLGG 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1231 EDTKNSLENErTRLSTILKETENHFT-----------------KTTQDLNATKAQLQKAQVEFAQKDEGGKELQCKLVAE 1293
Cdd:TIGR02168  625 VLVVDDLDNA-LELAKKLRPGYRIVTldgdlvrpggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1294 VELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEHRFhareQELAQRLEEGRGREKRLEDQKHNLEVCLAD 1373
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERI----AQLSKELTELEAEIEELEERLEEAEEELAE 779

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1374 ATQQIQELKARLGGAEGRIRALDEQLScvelhkrdteqKLSSVVHTLRRIAGIQVDGSVNLSHRLLSPSRRFspsrscgd 1453
Cdd:TIGR02168  780 AEAEIEELEAQIEQLKEELKALREALD-----------ELRAELTLLNEEAANLRERLESLERRIAATERRL-------- 840

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1454 ydnrstsqcpdgpidvdpDLVRKGVRNLMHQVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEE 1533
Cdd:TIGR02168  841 ------------------EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEE 902

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1534 KSNLETDRKMKISAIQALEEKLKHRNDECQMLRERLAQTEMQLAA----TSEENGQNEERLEKSRQQC-SKLDNEKRQLQ 1608
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEeyslTLEEAEALENKIEDDEEEArRRLKRLENKIK 982

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 665394924  1609 ----------EELAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCSIRQ 1648
Cdd:TIGR02168  983 elgpvnlaaiEEYEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARE 1032
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 792-1361 8.37e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 83.83  E-value: 8.37e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  792 QLEKEKILQDLACVTRDRGDIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLHEKD 871
Cdd:COG1196   224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQD 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  872 THRLNELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQcQRKAQETKTQLLN 951
Cdd:COG1196   304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE-AEAELAEAEEELE 382

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  952 AARAAESDFNQKIANLQAcAEEAAKRHGEEILQLRNALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEE 1031
Cdd:COG1196   383 ELAEELLEALRAAAELAA-QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1032 ALIRAESEKQQALLIAHRDkQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKL 1111
Cdd:COG1196   462 LELLAELLEEAALLEAALA-ELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAAL 540

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1112 EECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDRMESTN----NELQDALRKSKEGEGFIDSLRKELTDCRRQLAD 1187
Cdd:COG1196   541 EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRaraaLAAALARGAIGAAVDLVASDLREADARYYVLGD 620

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1188 SNIERDKYSGSNKELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKA 1267
Cdd:COG1196   621 TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALL 700

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1268 QLQKAQVEFAQKDEggkelqcklvAEVELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEhrfhAREQELA 1347
Cdd:COG1196   701 AEEEEERELAEAEE----------ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP----PDLEELE 766

                         570
                  ....*....|....
gi 665394924 1348 QRLEEGRGREKRLE 1361
Cdd:COG1196   767 RELERLEREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 254-1025 1.66e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 83.18  E-value: 1.66e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   254 DLQKLTNDWASLRDELLIKEDEFKEEEQAFKDyYNSEHNRLLKMWREVVAVKRSFKEMQTAMKAEVAKMGQEINCVGKDI 333
Cdd:TIGR02168  226 ELALLVLRLEELREELEELQEELKEAEEELEE-LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQK 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   334 NGSNATVAFAVQQAKRaADDELKQSQRSNDELQNQLATLKVQYESARHEIMERDQRLLELMNQLKKLEDRCAQAESQAAL 413
Cdd:TIGR02168  305 QILRERLANLERQLEE-LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLET 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   414 ASRYSDEIER---LNNSMREIAQAVVQDAENADREADAEVTGGVMQHMHLTRDAASVVGGAGGAGSTAGGGGKSPRRN-- 488
Cdd:TIGR02168  384 LRSKVAQLELqiaSLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEal 463

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   489 -STRASQAFAEGTISAVQAALHKYQL---ALHDMQVKFQNTSETLRTTKAQLETSEGTKQLLTTKMqQLTEKLDSSnskL 564
Cdd:TIGR02168  464 eELREELEEAEQALDAAERELAQLQArldSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELI-SVDEGYEAA---I 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   565 SELLQER------ESLQRGLDDIRVQKqQSEMGRA-----DINSAFENLSSDYEKMQLNCGKLQKRIDSMEED---KKAV 630
Cdd:TIGR02168  540 EAALGGRlqavvvENLNAAKKAIAFLK-QNELGRVtflplDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDpklRKAL 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   631 ELEIQRILKDKNITE-LNLRSEEDRSSR---LREETISLREELNRVSLNRDL-LEQQRIESDNLINLLEKQKSDLEydld 705
Cdd:TIGR02168  619 SYLLGGVLVVDDLDNaLELAKKLRPGYRivtLDGDLVRPGGVITGGSAKTNSsILERRREIEELEEKIEELEEKIA---- 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   706 klllekcdlqekheklsnnscSTSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDKARLELETDNLSAG 785
Cdd:TIGR02168  695 ---------------------ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLS 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   786 EKLKCLQLEKEKILQDLAcvtrdrgDIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVI 865
Cdd:TIGR02168  754 KELTELEAEIEELEERLE-------EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   866 DLHEKDTHRLNELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQET 945
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELREL 906

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   946 KTQlLNAARAAESDFNQKIANLQAcAEEAAKRHGEEILQLRNALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLESL 1025
Cdd:TIGR02168  907 ESK-RSELRRELEELREKLAQLEL-RLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 745-1413 2.38e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 82.42  E-value: 2.38e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   745 ERKKL--RIQSVDQCNEigELKKELAILDKARLELETDNLSAGEK---LKCLQLEKEKILQDLACVTRDRG----DIHNQ 815
Cdd:TIGR02169  154 ERRKIidEIAGVAEFDR--KKEKALEELEEVEENIERLDLIIDEKrqqLERLRREREKAERYQALLKEKREyegyELLKE 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   816 LTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVI-DLHEKDTHRLNELLAALRSEKESLESVLF 894
Cdd:TIGR02169  232 KEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIkDLGEEEQLRVKEKIGELEAEIASLERSIA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   895 DTNTSLEATEERRSQ--------------LERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQlLNAARAAESDF 960
Cdd:TIGR02169  312 EKERELEDAEERLAKleaeidkllaeieeLEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKE-FAETRDELKDY 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   961 NQKIANL----------QACAEEAAKRHGEEILQLRNALEKRMQQ--ALQALQTAKDDEIEKLQERLATLQAHLESLVQQ 1028
Cdd:TIGR02169  391 REKLEKLkreinelkreLDRLQEELQRLSEELADLNAAIAGIEAKinELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1029 HeealiRAESEKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKdemvqmrTKEEEHK 1108
Cdd:TIGR02169  471 L-----YDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLG-------SVGERYA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1109 IKLE-------------------ECI---------RKQELQLSSLREERESLCRVSEELKMEIRLK-------------- 1146
Cdd:TIGR02169  539 TAIEvaagnrlnnvvveddavakEAIellkrrkagRATFLPLNKMRDERRDLSILSEDGVIGFAVDlvefdpkyepafky 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1147 -------------------EDRMESTNNELQD-------ALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKysgsnk 1200
Cdd:TIGR02169  619 vfgdtlvvedieaarrlmgKYRMVTLEGELFEksgamtgGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSS------ 692

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1201 eLRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKD 1280
Cdd:TIGR02169  693 -LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELE 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1281 EGGKELQCKLvAEVELKER------AQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEhrfhAREQELAQRLEEGR 1354
Cdd:TIGR02169  772 EDLHKLEEAL-NDLEARLShsripeIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLE----KEIQELQEQRIDLK 846

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 665394924  1355 GREKRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTEQKL 1413
Cdd:TIGR02169  847 EQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 226-1027 4.51e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.64  E-value: 4.51e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   226 RCEQIVAQNSALRQQLEESNRTNEALTNDLQKLTNDWASLRDELLIKEDEFKEEEQAFKDYYNsEHNRLLKMWREVVAVK 305
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALAN-EISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   306 RSFKEMQTAMKAEVAKMGQEINCVGKDINgSNATVAFAVQQAKRAADDELKQSQRSNDELQNQLATLKVQYESARHEIME 385
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELA-ELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   386 RDQRLLELMNQLKKLEDRCAQAEsqaalasrysdeiERLNNSMREIAQAVVQDAENADREADAEVTggvmqhmhlTRDAA 465
Cdd:TIGR02168  391 LELQIASLNNEIERLEARLERLE-------------DRRERLQQEIEELLKKLEEAELKELQAELE---------ELEEE 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   466 SVVGGAGGAGSTAGGGGKSPRRNSTRASQAFAEGTISAVQAALHkyqlALHDMQVKFQNTSETLRTTKAQLETSEGTKQL 545
Cdd:TIGR02168  449 LEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD----SLERLQENLEGFSEGVKALLKNQSGLSGILGV 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   546 LTTKMQqLTEKLDSSnskLSELLQER------ESLQRGLDDIRVQKQqSEMGRA-----DINSAFENLSSDYEKMQLNCG 614
Cdd:TIGR02168  525 LSELIS-VDEGYEAA---IEAALGGRlqavvvENLNAAKKAIAFLKQ-NELGRVtflplDSIKGTEIQGNDREILKNIEG 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   615 KLQKRIDSMEED---KKAVELEIQRILKDKNITE-LNLRSEEDRSSR---LREETISLREELNRVSLNRDL-LEQQRIES 686
Cdd:TIGR02168  600 FLGVAKDLVKFDpklRKALSYLLGGVLVVDDLDNaLELAKKLRPGYRivtLDGDLVRPGGVITGGSAKTNSsILERRREI 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   687 DNLINLLEKQKSD---LEYDLDKLLLEKCDLQEKHEKLSNNSCSTSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGEL 763
Cdd:TIGR02168  680 EELEEKIEELEEKiaeLEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTEL 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   764 KKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAmcrkkeaLNEELMRTRQRLEQTTET 843
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTL-------LNEEAANLRERLESLERR 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   844 NSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEalvrees 923
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRE------- 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   924 LKNHVARLQKELEQCQrkaqetktQLLNAARAAESDFNQKIANLQACAEEAAKRHGEEILQLRNALEKRMQQA---LQAL 1000
Cdd:TIGR02168  906 LESKRSELRRELEELR--------EKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEArrrLKRL 977

                          810       820       830
                   ....*....|....*....|....*....|....*..
gi 665394924  1001 QTAKD----------DEIEKLQERLATLQAHLESLVQ 1027
Cdd:TIGR02168  978 ENKIKelgpvnlaaiEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 815-1615 6.32e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.26  E-value: 6.32e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   815 QLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLESVLF 894
Cdd:TIGR02168  226 ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   895 DTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKtQLLNAARAAESDFNQKIANLQACAEEA 974
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLE-AELEELEAELEELESRLEELEEQLETL 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   975 AKrhgeEILQLRNALEkrmqqALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEEAliraesekqqalliahrDKQAV 1054
Cdd:TIGR02168  385 RS----KVAQLELQIA-----SLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA-----------------ELKEL 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1055 AERLEavsrDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECIRKQELQLSSLREERE---- 1130
Cdd:TIGR02168  439 QAELE----ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKAllkn 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1131 ------SLCRVSE--------ELKMEIRLKEDR----MESTN--NELQDALRKSKEG---------------EGFIDSLR 1175
Cdd:TIGR02168  515 qsglsgILGVLSElisvdegyEAAIEAALGGRLqavvVENLNaaKKAIAFLKQNELGrvtflpldsikgteiQGNDREIL 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1176 KELTDCRRQLADSNIERDKYSGSNKELRDHVKRVESAKREQARAIE-EALQKISNLEDTK-----------NSLENERTR 1243
Cdd:TIGR02168  595 KNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKlRPGYRIVTLDGDLvrpggvitggsAKTNSSILE 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1244 LSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKELQcklvaevELKERAQQELCQIKKQLSDLEanlcATRQ 1323
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLR-------KELEELSRQISALRKDLARLE----AEVE 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1324 ELGRARCQNNQEEHRFHAREQELAQRLEEGRGREKRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDE----QL 1399
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEeaanLR 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1400 SCVELHKRDTEQKLSSVVHTLRRIAGIQVDG-SVNLSHRLLSPSRRFSPSRSCGDYDNRSTSQcpdgpidVDPDLVRKGV 1478
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIeSLAAEIEELEELIEELESELEALLNERASLE-------EALALLRSEL 896

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1479 RNLMHQVAQLEREKDDYKSQLGAAKKQLQDAadqqlrcDAKLGKLQAMLRNLQEEKSNLETDrkmkisAIQALEEKLKHR 1558
Cdd:TIGR02168  897 EELSEELRELESKRSELRRELEELREKLAQL-------ELRLEGLEVRIDNLQERLSEEYSL------TLEEAEALENKI 963

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 665394924  1559 NDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVE 1615
Cdd:TIGR02168  964 EDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLE 1020
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 556-1152 1.86e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 79.60  E-value: 1.86e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  556 KLDSSNSKLSELLQERESLQRGLDDIRVQKQQSEMGRADINSAFENLSSDYEKMQLNCGKLQKRIDSMEEDKKAVELEIQ 635
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  636 RILKDKNITELNLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQRIESDNLINLLEKQKSDLEYDLDKLLLEKCDLQ 715
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  716 EKHEKLSNnscstsdELKSVQNCLQEAQEERKKLRiqsvdqcNEIGELKKELAILDKARLELETDNLSAGEKLKCLQLEK 795
Cdd:COG1196   393 RAAAELAA-------QLEELEEAEEALLERLERLE-------EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  796 EKILQDLACVTRDRgdihnqltamcRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLhekdtHRL 875
Cdd:COG1196   459 EALLELLAELLEEA-----------ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGL-----RGL 522

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  876 NELLAALRSEKESLESVLfdtntSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEqcQRKAQETKTQLLNAARA 955
Cdd:COG1196   523 AGAVAVLIGVEAAYEAAL-----EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLP--LDKIRARAALAAALARG 595

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  956 AESDFNQKIANLQACAEEAAKRHGEEILqLRNALEKRMQQALQALQTAKDDEIEKLQERlatlqahleSLVQQHEEALIR 1035
Cdd:COG1196   596 AIGAAVDLVASDLREADARYYVLGDTLL-GRTLVAARLEAALRRAVTLAGRLREVTLEG---------EGGSAGGSLTGG 665

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1036 AESEKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECI 1115
Cdd:COG1196   666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEE 745

                         570       580       590
                  ....*....|....*....|....*....|....*..
gi 665394924 1116 RKQELQLSSLREERESLcrvsEELKMEIRLKEDRMES 1152
Cdd:COG1196   746 ELLEEEALEELPEPPDL----EELERELERLEREIEA 778
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
536-1113 6.36e-14

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 77.80  E-value: 6.36e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  536 LETSEGTKQLLTTKMQQLTEKLdssnSKLSELLQERESLQRGLDDIRVQKQQSEmgraDINSAFENLSSDYEKMQLNCGK 615
Cdd:PRK03918  185 IKRTENIEELIKEKEKELEEVL----REINEISSELPELREELEKLEKEVKELE----ELKEEIEELEKELESLEGSKRK 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  616 LQKRIDSMEEDKKAVELEIQRIlkDKNITELN-LRSEEDRSSRLREETISLREELNRVSLNRDLLEQQRIESDNLINLLE 694
Cdd:PRK03918  257 LEEKIRELEERIEELKKEIEEL--EEKVKELKeLKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELE 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  695 KQKSDLEY---DLDKLLLEKCDLQEKHEKLsnnscstsDELKSVQNCLQEAQEERKklriqsvdqCNEIGELKKELAILD 771
Cdd:PRK03918  335 EKEERLEElkkKLKELEKRLEELEERHELY--------EEAKAKKEELERLKKRLT---------GLTPEKLEKELEELE 397

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  772 KARLELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGD--IHNQLTAMCRKKEALNE---ELMRTRQRLEQTTETNSR 846
Cdd:PRK03918  398 KAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpVCGRELTEEHRKELLEEytaELKRIEKELKEIEEKERK 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  847 LNRNLEEMVKDVEEKQVVIdlhekdthRLNELLAALRSEKESLESV----LFDTNTSLEATEERRSQLE---RDLQEALV 919
Cdd:PRK03918  478 LRKELRELEKVLKKESELI--------KLKELAEQLKELEEKLKKYnleeLEKKAEEYEKLKEKLIKLKgeiKSLKKELE 549

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  920 REESLKNHVARLQKELEQCQRKAQETKTQLLNAARAAESDFNQKIANLqacaEEAAKRHgeeiLQLRNAlEKRMQQALQA 999
Cdd:PRK03918  550 KLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL----EPFYNEY----LELKDA-EKELEREEKE 620

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1000 LQTAKdDEIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAHRDKQ----AVAERLEAVSRDLKTEQESLDRS 1075
Cdd:PRK03918  621 LKKLE-EELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSrelaGLRAELEELEKRREEIKKTLEKL 699

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|
gi 665394924 1076 RREANARDEKQR--AAIAQLKDEMVQMRTKEEEHKIKLEE 1113
Cdd:PRK03918  700 KEELEEREKAKKelEKLEKALERVEELREKVKKYKALLKE 739
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 703-1380 6.37e-14

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 77.85  E-value: 6.37e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   703 DLDKLLLEKCDLQEKHEKLSNNScstsdeLKSVQNCLQEAQEERKKL----RIQSVDQCNEIGELKKELAILDKARL--- 775
Cdd:pfam15921   89 DLQRRLNESNELHEKQKFYLRQS------VIDLQTKLQEMQMERDAMadirRRESQSQEDLRNQLQNTVHELEAAKClke 162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   776 ELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGD----------------IHNQLTAMCRKKEALNEELMRTRQRL-- 837
Cdd:pfam15921  163 DMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEasgkkiyehdsmstmhFRSLGSAISKILRELDTEISYLKGRIfp 242

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   838 -EQTTETNSRLNRNLEEMVKDVEEKQV--VIDLHEKDTHRLNELLAALRSEKESLESVLfdtNTSLEATEERRSQLERDL 914
Cdd:pfam15921  243 vEDQLEALKSESQNKIELLLQQHQDRIeqLISEHEVEITGLTEKASSARSQANSIQSQL---EIIQEQARNQNSMYMRQL 319

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   915 QEalvreesLKNHVARLQKELEQCQR----KAQETKTQL------LNAARAAESDFNQKIANL----QACAEEAAKRHGE 980
Cdd:pfam15921  320 SD-------LESTVSQLRSELREAKRmyedKIEELEKQLvlanseLTEARTERDQFSQESGNLddqlQKLLADLHKREKE 392

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   981 eiLQLRNALEKRMQQ-------ALQALQTAKDD---EIEKLQERLATLQAHLESLVQQhEEALIRAESEKQQALLIAHRD 1050
Cdd:pfam15921  393 --LSLEKEQNKRLWDrdtgnsiTIDHLRRELDDrnmEVQRLEALLKAMKSECQGQMER-QMAAIQGKNESLEKVSSLTAQ 469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1051 KQAVAERLEAVSRDLKTEQESLDRSRREAN----ARDEKQRAaIAQLKDEMVQMRTKEEehkIKLEEC--IRKQELQLSS 1124
Cdd:pfam15921  470 LESTKEMLRKVVEELTAKKMTLESSERTVSdltaSLQEKERA-IEATNAEITKLRSRVD---LKLQELqhLKNEGDHLRN 545

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1125 LREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKELRD 1204
Cdd:pfam15921  546 VQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEA 625

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1205 HVKRVESAKREQARAIEEALQKISNLEDTKNSLENE----RTRLSTILKETE---NHFTKTTQDLNAT----KAQLQKAQ 1273
Cdd:pfam15921  626 RVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEvktsRNELNSLSEDYEvlkRNFRNKSEEMETTtnklKMQLKSAQ 705

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1274 VEFAQKDEGGKELQCKLVAEVELKERAQQELCQIKKQLSDLEANLcatrQELGRARCQNNQEEHRFHAREQELAQ----- 1348
Cdd:pfam15921  706 SELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKI----QFLEEAMTNANKEKHFLKEEKNKLSQelstv 781

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 665394924  1349 ---------RLEEGRGREKRLEDQKHNLEVCLADATQQIQE 1380
Cdd:pfam15921  782 ateknkmagELEVLRSQERRLKEKVANMEVALDKASLQFAE 822
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
811-1385 9.32e-14

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 77.00  E-value: 9.32e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  811 DIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSrlnrNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLE 890
Cdd:PRK02224  203 DLHERLNGLESELAELDEEIERYEEQREQARETRD----EADEVLEEHEERREELETLEAEIEDLRETIAETEREREELA 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  891 SVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQEtktqllnaARAAESDFNQKIANLQAC 970
Cdd:PRK02224  279 EEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEE--------CRVAAQAHNEEAESLRED 350

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  971 AEEAAKRhGEEILQLRNALEKRMQQALQALQTAK------DDEIEKLQERLATLQAHLESLVQQHEEAL-----IRAESE 1039
Cdd:PRK02224  351 ADDLEER-AEELREEAAELESELEEAREAVEDRReeieelEEEIEELRERFGDAPVDLGNAEDFLEELReerdeLREREA 429

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1040 KQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQraaIAQLKDEMVQMRTKEEEHKIKLE--ECIRK 1117
Cdd:PRK02224  430 ELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRER---VEELEAELEDLEEEVEEVEERLEraEDLVE 506

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1118 QELQLSSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERdkysG 1197
Cdd:PRK02224  507 AEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKL----A 582

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1198 SNKElrdhvkrvesaKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFA 1277
Cdd:PRK02224  583 ELKE-----------RIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEA 651

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1278 QKDeggkelqcklvaevelKERAQQELCQIKKQLSDLEANLCATRQELGrarcqnnqeehrfhAREQELaQRLEEGRGRE 1357
Cdd:PRK02224  652 RED----------------KERAEEYLEQVEEKLDELREERDDLQAEIG--------------AVENEL-EELEELRERR 700

                         570       580
                  ....*....|....*....|....*...
gi 665394924 1358 KRLEDQKHNLEVcLADATQQIQELKARL 1385
Cdd:PRK02224  701 EALENRVEALEA-LYDEAEELESMYGDL 727
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 615-1304 1.46e-13

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 76.21  E-value: 1.46e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   615 KLQKRIDSMEEDKKAVELEIQRILKDKNITELNLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQRIESDNLINLLE 694
Cdd:TIGR04523   37 QLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDK 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   695 KQKSDLEYDLDKLLLEKCDLQEKHEKLSNNSCSTSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDKAR 774
Cdd:TIGR04523  117 EQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKL 196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   775 LELETdNLSAGEKLKCLQLEKEKILQDLacvTRDRGDIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEM 854
Cdd:TIGR04523  197 LKLEL-LLSNLKKKIQKNKSLESQISEL---KKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEK 272

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   855 VKDVEEKQVVIDLHEKDTHRLNELLAALRSEKEslESVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKE 934
Cdd:TIGR04523  273 QKELEQNNKKIKELEKQLNQLKSEISDLNNQKE--QDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKE 350

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   935 LEQCQRKAQETKTQLLNAARAAESDFNQKIANLQacaeeaakrhgeEILQLRNALEKRMQQALQALQTAKddeieKLQER 1014
Cdd:TIGR04523  351 LTNSESENSEKQRELEEKQNEIEKLKKENQSYKQ------------EIKNLESQINDLESKIQNQEKLNQ-----QKDEQ 413

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1015 LATLQAHLESLVQQHEEalIRAESEKQQALLIAHRDKQAVAE----RLEAVSRDLKTEQESLDRSRREANARDEKQRAAI 1090
Cdd:TIGR04523  414 IKKLQQEKELLEKEIER--LKETIIKNNSEIKDLTNQDSVKEliikNLDNTRESLETQLKVLSRSINKIKQNLEQKQKEL 491

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1091 AQLKDEMVQMRtkeeEHKIKLEECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDRMESTNNELqdalrKSKEGEGF 1170
Cdd:TIGR04523  492 KSKEKELKKLN----EEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFEL-----KKENLEKE 562

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1171 IDSLRKELTdcrrQLADSNIERDKysgSNKELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKE 1250
Cdd:TIGR04523  563 IDEKNKEIE----ELKQTQKSLKK---KQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKN 635

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....
gi 665394924  1251 TENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKELQCKLVAEVELKERAQQEL 1304
Cdd:TIGR04523  636 IKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIELMKDWLKEL 689
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 615-1403 2.70e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.87  E-value: 2.70e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   615 KLQKRIDSMEEDKKAVElEIQRILKDKNITELNLRSEEDRSSRLREETISLRE-ELNRVSLNRDLLEQQRIESDNLINLL 693
Cdd:TIGR02169  171 KKEKALEELEEVEENIE-RLDLIIDEKRQQLERLRREREKAERYQALLKEKREyEGYELLKEKEALERQKEAIERQLASL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   694 EKQKSDLEYDLDKLLLEKCDLQEKHEKLSNN-SCSTSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDK 772
Cdd:TIGR02169  250 EEELEKLTEEISELEKRLEEIEQLLEELNKKiKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEA 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   773 ARLELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLE 852
Cdd:TIGR02169  330 EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELD 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   853 EMVKDVEEKqvvidlhEKDTHRLNELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQ 932
Cdd:TIGR02169  410 RLQEELQRL-------SEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVE 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   933 KELEQCQRKAQETKTQLLNA------ARAAESDFNQKIANLQACAEEAAKRHGEEILQLRNALEKRMQQ--------ALQ 998
Cdd:TIGR02169  483 KELSKLQRELAEAEAQARASeervrgGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNvvveddavAKE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   999 ALQTAKDDEI--------EKLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAHRDKQAV-----AERLEAVSRDL 1065
Cdd:TIGR02169  563 AIELLKRRKAgratflplNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVedieaARRLMGKYRMV 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1066 KTEQESLDRSRREANARDEKQRAAIAQlkdemvqmrtkeeehkikleeciRKQELQLSSLREERESLCRVSEELKMEIRL 1145
Cdd:TIGR02169  643 TLEGELFEKSGAMTGGSRAPRGGILFS-----------------------RSEPAELQRLRERLEGLKRELSSLQSELRR 699

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1146 KEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKELRDHVKRVES---AKREQARAIEE 1222
Cdd:TIGR02169  700 IENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEArieELEEDLHKLEE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1223 AL---------QKISNLEDTKNSLENERTRLSTILKETEnhftkttqdlnatkAQLQKAQVEFAQKDEGGKELQCKLVAE 1293
Cdd:TIGR02169  780 ALndlearlshSRIPEIQAELSKLEEEVSRIEARLREIE--------------QKLNRLTLEKEYLEKEIQELQEQRIDL 845

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1294 VELKERAQQELCQIKKQLSDLEANLcatrqelgrarcqnnqEEHRfhAREQELAQRLEEGRGREKRLEDQKHNLEVCLAD 1373
Cdd:TIGR02169  846 KEQIKSIEKEIENLNGKKEELEEEL----------------EELE--AALRDLESRLGDLKKERDELEAQLRELERKIEE 907

                          810       820       830
                   ....*....|....*....|....*....|
gi 665394924  1374 ATQQIQELKARLGGAEGRIRALDEQLSCVE 1403
Cdd:TIGR02169  908 LEAQIEKKRKRLSELKAKLEALEEELSEIE 937
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
890-1397 4.04e-13

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 75.08  E-value: 4.04e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  890 ESVLFDTNTSLEATEERRSQLE-RDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLLNA------ARAAESDFNQ 962
Cdd:PRK02224  179 ERVLSDQRGSLDQLKAQIEEKEeKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVleeheeRREELETLEA 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  963 KIANLQACAEEAAKR---HGEEILQLRNALEKRMQQALQALQTA--KDDEIEKLQERLATLQAHLESLVQQHEEALIRAE 1037
Cdd:PRK02224  259 EIEDLRETIAETEREreeLAEEVRDLRERLEELEEERDDLLAEAglDDADAEAVEARREELEDRDEELRDRLEECRVAAQ 338

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1038 SEKQQALLIAHRdkqavAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECirk 1117
Cdd:PRK02224  339 AHNEEAESLRED-----ADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNA--- 410

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1118 qELQLSSLREERESLCRVSEELKMEIRLKEDRMEStNNELQDALRKSKEGEGFIDSLRKE-LTDCRRQLADSNIERDKYS 1196
Cdd:PRK02224  411 -EDFLEELREERDELREREAELEATLRTARERVEE-AEALLEAGKCPECGQPVEGSPHVEtIEEDRERVEELEAELEDLE 488

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1197 GSNKELRDHVKRVESAKrEQARAIEEALQKISNLE----DTKNSLENERTRLSTILKETENHFTKTtqdlNATKAQLQKA 1272
Cdd:PRK02224  489 EEVEEVEERLERAEDLV-EAEDRIERLEERREDLEeliaERRETIEEKRERAEELRERAAELEAEA----EEKREAAAEA 563

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1273 QVEFAQKDEGGKELQCKLVaevELKERAQQeLCQIKKQLSDLEANlcatRQELGRAR-------CQNNQEEHRFHA---R 1342
Cdd:PRK02224  564 EEEAEEAREEVAELNSKLA---ELKERIES-LERIRTLLAAIADA----EDEIERLRekrealaELNDERRERLAEkreR 635

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1343 EQELAQ-----RLEEGRGREKRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDE 1397
Cdd:PRK02224  636 KRELEAefdeaRIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEE 695
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1487-1783 4.53e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.97  E-value: 4.53e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1487 QLEREKDDYKSQLGAAKKQLQDAADQQLRcdAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEEKLKHRNDECQMLR 1566
Cdd:COG1196   217 ELKEELKELEAELLLLKLRELEAELEELE--AELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1567 ERLAQTEMQLAATSEENGQNEERLEksrqqcskldnekrQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCSI 1646
Cdd:COG1196   295 AELARLEQDIARLEERRRELEERLE--------------ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAEL 360

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1647 RQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEQGHCSQANEDKLKLVQKSLQTA 1726
Cdd:COG1196   361 AEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE 440

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 665394924 1727 ENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQLRIAK 1783
Cdd:COG1196   441 EEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLL 497
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
821-1382 1.48e-12

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 73.17  E-value: 1.48e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  821 RKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVK------DVEEKQVVIDLHEKDTHRLNELLAALRSEKESLESvlf 894
Cdd:PRK03918  176 RRIERLEKFIKRTENIEELIKEKEKELEEVLREINEisselpELREELEKLEKEVKELEELKEEIEELEKELESLEG--- 252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  895 dtntSLEATEERRSQLERDLQEALVREESLKNHVarlqKELEQCQRKAQETKTqllnaARAAESDFNQKIANLqacaEEA 974
Cdd:PRK03918  253 ----SKRKLEEKIRELEERIEELKKEIEELEEKV----KELKELKEKAEEYIK-----LSEFYEEYLDELREI----EKR 315

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  975 AKRHGEEIlqlrNALEKRMQQAlqalqTAKDDEIEKLQERLATLQAHLESLVQQHEEaLIRAESEKQQALLIAHRDKQAV 1054
Cdd:PRK03918  316 LSRLEEEI----NGIEERIKEL-----EEKEERLEELKKKLKELEKRLEELEERHEL-YEEAKAKKEELERLKKRLTGLT 385

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1055 AERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQM-----------RTKEEEHKiklEECIRKQELQLS 1123
Cdd:PRK03918  386 PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELkkakgkcpvcgRELTEEHR---KELLEEYTAELK 462

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1124 SLREERESLcrvsEELKMEIRLKEDRMESTNNElQDALRKSKEGEGFIDSLRKELtdcrrqladSNIERDKYSGSNKELR 1203
Cdd:PRK03918  463 RIEKELKEI----EEKERKLRKELRELEKVLKK-ESELIKLKELAEQLKELEEKL---------KKYNLEELEKKAEEYE 528

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1204 DHVKRVESAKREQaRAIEEALQKISNLEDTKNSLENE----RTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQK 1279
Cdd:PRK03918  529 KLKEKLIKLKGEI-KSLKKELEKLEELKKKLAELEKKldelEEELAELLKELEELGFESVEELEERLKELEPFYNEYLEL 607

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1280 DEGGKELQCKLvaevELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEHRFHARE-QELAQRLEEGRGREK 1358
Cdd:PRK03918  608 KDAEKELEREE----KELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEyLELSRELAGLRAELE 683

                         570       580
                  ....*....|....*....|....
gi 665394924 1359 RLEDQKHNLEVCLADATQQIQELK 1382
Cdd:PRK03918  684 ELEKRREEIKKTLEKLKEELEERE 707
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 524-1252 3.64e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.02  E-value: 3.64e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   524 NTSETLRTTKAQLETSEGTkqLLTTKMQQLTEKLDSSNSKLSELLQERESLQRGLDDIRVQKQQSEMGRADINSAFENLS 603
Cdd:TIGR02169  208 EKAERYQALLKEKREYEGY--ELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLG 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   604 SD-YEKMQLNCGKLQKRIDSMEEDKKAVELEIQRILKDKNITELNLRseedrssRLREETISLREELNRVSLNRDLLEQQ 682
Cdd:TIGR02169  286 EEeQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEID-------KLLAEIEELEREIEEERKRRDKLTEE 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   683 RIESDNLINLLEKQKSDLEYDLDKLLLEKCDLQEKHEKLsnnscstSDELKSVQNCLQEAQEERKKLRIqsvdqcnEIGE 762
Cdd:TIGR02169  359 YAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKL-------KREINELKRELDRLQEELQRLSE-------ELAD 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   763 LKKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAMCRKKEALNEELMRTRQRLeQTTE 842
Cdd:TIGR02169  425 LNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA-RASE 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   843 TNSRLNRNLEEMVKD--------------VEEK--------------QVVID-----------LHEKDTHR-----LNEL 878
Cdd:TIGR02169  504 ERVRGGRAVEEVLKAsiqgvhgtvaqlgsVGERyataievaagnrlnNVVVEddavakeaielLKRRKAGRatflpLNKM 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   879 LAALR-SEKESLESVLFDTNTSLEATEERRSQLERDLQEALVRE--ESLKNHVARLQK-ELEQCQRKAQETKTQLLNAAR 954
Cdd:TIGR02169  584 RDERRdLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVEdiEAARRLMGKYRMvTLEGELFEKSGAMTGGSRAPR 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   955 AAESDFNQKIANLQACAE--EAAKRHGEEILQLRNALEKRMQQALQALQTAKdDEIEKLQERLATLQAHLESLVQQHEEa 1032
Cdd:TIGR02169  664 GGILFSRSEPAELQRLRErlEGLKRELSSLQSELRRIENRLDELSQELSDAS-RKIGEIEKEIEQLEQEEEKLKERLEE- 741

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1033 LIRAESEKQQALLIAHRDKQAVAERLEAVSRDLKTEQESL-DRSRREANARDEKQRAAIAQLKDEmvqmRTKEEEHKIKL 1111
Cdd:TIGR02169  742 LEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALnDLEARLSHSRIPEIQAELSKLEEE----VSRIEARLREI 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1112 EECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLadsnie 1191
Cdd:TIGR02169  818 EQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKER------ 891

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 665394924  1192 rdkysgsnKELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETE 1252
Cdd:TIGR02169  892 --------DELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDE 944
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1121-1704 1.41e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 69.97  E-value: 1.41e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1121 QLSSLREERESLcRVSEELKMEIRLKEdrMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNK 1200
Cdd:COG1196   201 QLEPLERQAEKA-ERYRELKEELKELE--AELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELE 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1201 ELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKD 1280
Cdd:COG1196   278 ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1281 EGGKELQCKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEHRFHAREQELAQRLEEGRGREKRL 1360
Cdd:COG1196   358 AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE 437

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1361 EDQKHNLEvclaDATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTEQKLSSVVHTLRRIAGIQVDgsvnlsHRLLS 1440
Cdd:COG1196   438 EEEEEALE----EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD------YEGFL 507

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1441 PSRRFSPSRSCGDYDNRSTSQCPDGPIDVDPDLVRKGVRNLMHQVAQLEREKDDYKSQLGAAKK------QLQDAADQQL 1514
Cdd:COG1196   508 EGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgratflPLDKIRARAA 587

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1515 RCDAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEERLEKSR 1594
Cdd:COG1196   588 LAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSR 667

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1595 QQCSKLDNEKRQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCSIRQMAERLENQ-NRALTQLEDRCTALKST 1673
Cdd:COG1196   668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQlEAEREELLEELLEEEEL 747

                         570       580       590
                  ....*....|....*....|....*....|.
gi 665394924 1674 VDQLKERLQKSAVSETQLRGEIKTLQKELSE 1704
Cdd:COG1196   748 LEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1485-1836 2.52e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 69.33  E-value: 2.52e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1485 VAQLEREKDDYKSQLGAAKKQLQdaadqqlRCDAKLGKLQAMLRNLQEEKSNLETDRKMKiSAIQALEEKLKHRndECQM 1564
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIE-------RLDLIIDEKRQQLERLRREREKAERYQALL-KEKREYEGYELLK--EKEA 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1565 LRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEEL-AKVEGRASKLELQRVAMEGDLTRLQMALQEKD 1643
Cdd:TIGR02169  235 LERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIkDLGEEEQLRVKEKIGELEAEIASLERSIAEKE 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1644 CSIRQMAERLEnqnraltQLEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEQghcsqanEDKLKLVQKSL 1723
Cdd:TIGR02169  315 RELEDAEERLA-------KLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDL-------RAELEEVDKEF 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1724 QTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQLRIAKWNQESGGDKdltnGNGGGNG 1803
Cdd:TIGR02169  381 AETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALE----IKKQEWK 456

                          330       340       350
                   ....*....|....*....|....*....|...
gi 665394924  1804 EEELSRQLKSSQREKSELRSKLQTLQDKVKQLE 1836
Cdd:TIGR02169  457 LEQLAADLSKYEQELYDLKEEYDRVEKELSKLQ 489
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 486-1253 3.39e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.94  E-value: 3.39e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   486 RRNSTRASQAFAEGTISAVQAALHKYQLALHDMQVKFQNTSETLRTTKAQLETSEGTKQL-LTTKMQQLTEKLDSSNSKL 564
Cdd:TIGR02169  231 EKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLrVKEKIGELEAEIASLERSI 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   565 SELLQERESLQRglddiRVQKQQSEMGRadINSAFENLSSDYEKMQLNCGKLQKRIDSMEEDKKAVELEIQRILKDKNIT 644
Cdd:TIGR02169  311 AEKERELEDAEE-----RLAKLEAEIDK--LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAET 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   645 ELNLRSEEDRSSRLREETISLREELNRVslnRDLLEQQRIESDNLINLLEkqksDLEYDLDKLLLEKCDLQEKHEKLSNN 724
Cdd:TIGR02169  384 RDELKDYREKLEKLKREINELKRELDRL---QEELQRLSEELADLNAAIA----GIEAKINELEEEKEDKALEIKKQEWK 456

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   725 SCSTSDELKSVQNCLQEAQEERKKLRiqsvdqcNEIGELKKELAILDKARLELETdnlsAGEKLKCLQLEKEKILQDLAC 804
Cdd:TIGR02169  457 LEQLAADLSKYEQELYDLKEEYDRVE-------KELSKLQRELAEAEAQARASEE----RVRGGRAVEEVLKASIQGVHG 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   805 VTRDRGDIH------------NQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRnLEEMVKDVE---EKQVV---ID 866
Cdd:TIGR02169  526 TVAQLGSVGeryataievaagNRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNK-MRDERRDLSilsEDGVIgfaVD 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   867 LHE-------------KDTHRLNELLAALRSEKE----SLESVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVA 929
Cdd:TIGR02169  605 LVEfdpkyepafkyvfGDTLVVEDIEAARRLMGKyrmvTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLE 684

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   930 RLQKELEQCQRKAQETKtQLLNAARAAESDFNQKIANLQACAEEAAKRHG---EEILQLRNALEKrMQQALQALQTAKDD 1006
Cdd:TIGR02169  685 GLKRELSSLQSELRRIE-NRLDELSQELSDASRKIGEIEKEIEQLEQEEEklkERLEELEEDLSS-LEQEIENVKSELKE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1007 ---EIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARD 1083
Cdd:TIGR02169  763 leaRIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQR 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1084 EKQRAAIAQLKDEMVQMRTKEEEhkikLEECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRK 1163
Cdd:TIGR02169  843 IDLKEQIKSIEKEIENLNGKKEE----LEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKR 918

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1164 SKEGEGFIDSLRKELTdcrrQLADSNIERDKYSGSNKELRDHVKRVESAKRE-------QARAI---EEALQKISNLEDT 1233
Cdd:TIGR02169  919 LSELKAKLEALEEELS----EIEDPKGEDEEIPEEELSLEDVQAELQRVEEEiralepvNMLAIqeyEEVLKRLDELKEK 994

                          810       820
                   ....*....|....*....|
gi 665394924  1234 KNSLENERTRLSTILKETEN 1253
Cdd:TIGR02169  995 RAKLEEERKAILERIEEYEK 1014
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1045-1770 3.89e-11

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 68.61  E-value: 3.89e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1045 LIAHRDKQAVAERLEAVSRDLKTEQESLDrsrrEANARDEKQRAaiaQLKDEMVQMRTKEEEHKIKLEEC--IRKQELQl 1122
Cdd:pfam15921   67 IIAYPGKEHIERVLEEYSHQVKDLQRRLN----ESNELHEKQKF---YLRQSVIDLQTKLQEMQMERDAMadIRRRESQ- 138

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1123 sSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDkySGSNKEL 1202
Cdd:pfam15921  139 -SQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHD--SMSTMHF 215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1203 RDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENE------------RTRLSTILKETENHFTKTTQDLNATKAQLQ 1270
Cdd:pfam15921  216 RSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSEsqnkielllqqhQDRIEQLISEHEVEITGLTEKASSARSQAN 295

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1271 KAQVEFAQkdeggkelqcklvaeveLKERAQQELCQIKKQLSDLEANLCATRQELGRARcqnNQEEHRFHAREQELA--- 1347
Cdd:pfam15921  296 SIQSQLEI-----------------IQEQARNQNSMYMRQLSDLESTVSQLRSELREAK---RMYEDKIEELEKQLVlan 355

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1348 QRLEEGRGREKRLEDQKHNLEvcladatQQIQELKARLGGAEGRIRALDEQLScvELHKRDTEQKLSsvVHTLRRiagiQ 1427
Cdd:pfam15921  356 SELTEARTERDQFSQESGNLD-------DQLQKLLADLHKREKELSLEKEQNK--RLWDRDTGNSIT--IDHLRR----E 420

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1428 VDGSvNLSHRLLSPSRRFSPSRSCGDYD---------NRSTSQCPD--GPIDVDPDLVRKGVRNLMHQVAQL---EREKD 1493
Cdd:pfam15921  421 LDDR-NMEVQRLEALLKAMKSECQGQMErqmaaiqgkNESLEKVSSltAQLESTKEMLRKVVEELTAKKMTLessERTVS 499

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1494 DYKSQLGAAKKQLQDAADQ----QLRCDAKLGKLQAM------LRNLQEEKSNLETDRKMKISAIQALEEKLKHrndecq 1563
Cdd:pfam15921  500 DLTASLQEKERAIEATNAEitklRSRVDLKLQELQHLknegdhLRNVQTECEALKLQMAEKDKVIEILRQQIEN------ 573

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1564 mLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKD 1643
Cdd:pfam15921  574 -MTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDIK 652

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1644 CSIRQMAERLENQNRALTQLEDRCTALK-----------STVDQLKERLQKSAVSETQLRGEIKT--------------L 1698
Cdd:pfam15921  653 QERDQLLNEVKTSRNELNSLSEDYEVLKrnfrnkseemeTTTNKLKMQLKSAQSELEQTRNTLKSmegsdghamkvamgM 732

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 665394924  1699 QKELSEQGHCSQANEDKLKLVQKSLQTAENEKRILTE-------RLDSAQTNLNELRRSQQAQLDGNQRLQEQVTDLEV 1770
Cdd:pfam15921  733 QKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEeknklsqELSTVATEKNKMAGELEVLRSQERRLKEKVANMEV 811
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
730-1316 6.12e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.78  E-value: 6.12e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  730 DELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAildkaRLELETDNLSAGEKLKCLQLEK-EKILQDLACVTRD 808
Cdd:PRK03918  165 KNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELE-----EVLREINEISSELPELREELEKlEKEVKELEELKEE 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  809 RGDIHNQLTAMCRKKEALNEELMRTRQRLEqttETNSRLnRNLEEMVKDVEEKQVVIDLHEKdthrLNELLAALRSEKES 888
Cdd:PRK03918  240 IEELEKELESLEGSKRKLEEKIRELEERIE---ELKKEI-EELEEKVKELKELKEKAEEYIK----LSEFYEEYLDELRE 311

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  889 LESvlfdtntSLEATEERRSQLERDLQEAlvreESLKNHVARLQKELEQCQRKAQETKT--QLLNAARaaesdfnQKIAN 966
Cdd:PRK03918  312 IEK-------RLSRLEEEINGIEERIKEL----EEKEERLEELKKKLKELEKRLEELEErhELYEEAK-------AKKEE 373

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  967 LQACAEEAAKRHGEEILQLRNALEKRmqqalqalQTAKDDEIEKLQERLATLqahlESLVQQHEEALIRAESEKQQ---- 1042
Cdd:PRK03918  374 LERLKKRLTGLTPEKLEKELEELEKA--------KEEIEEEISKITARIGEL----KKEIKELKKAIEELKKAKGKcpvc 441

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1043 -ALLIAHRDKQAVAERLEAVSRDLKTEQEsLDRSRREANARDEKQRAAIAQLKdEMVQMRTKEEEHKiKLEECIRKQELQ 1121
Cdd:PRK03918  442 gRELTEEHRKELLEEYTAELKRIEKELKE-IEEKERKLRKELRELEKVLKKES-ELIKLKELAEQLK-ELEEKLKKYNLE 518

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1122 -LSSLREERESLCRVSEELKMEIRLKEDRMESTNnELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERD------- 1193
Cdd:PRK03918  519 eLEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLE-ELKKKLAELEKKLDELEEELAELLKELEELGFESVEELeerlkel 597

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1194 -KYSGSNKELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILK--------ETENHFTKTTQDLNA 1264
Cdd:PRK03918  598 ePFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKkyseeeyeELREEYLELSRELAG 677

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|..
gi 665394924 1265 TKAQLQKAQvefAQKDEGGKELQcKLVAEVELKERAQQELCQIKKQLSDLEA 1316
Cdd:PRK03918  678 LRAELEELE---KRREEIKKTLE-KLKEELEEREKAKKELEKLEKALERVEE 725
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
527-1032 1.47e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 66.60  E-value: 1.47e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  527 ETLRTTKAQLETSEGTKQLLTTkmqqLTEKLDSSNSKLSELLQERESLQrglDDIRVQKQQSEMGRADINSAFENL---S 603
Cdd:PRK02224  234 ETRDEADEVLEEHEERREELET----LEAEIEDLRETIAETEREREELA---EEVRDLRERLEELEEERDDLLAEAgldD 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  604 SDYEKMQLNCGKLQKRIDSMEEDKKAVELEIQRILKDKNITELNLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQR 683
Cdd:PRK02224  307 ADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEI 386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  684 IESDNLINLLEKQKSDLEYDLDKLLLEKCDLQEKHEKLSNNSCSTSDELKSVQNCLQEAQEERKK-------------LR 750
Cdd:PRK02224  387 EELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvegsPH 466

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  751 IQSVDQCNE-IGELKKELAILDKARLELEtDNLSAGEKLKCLQLEKEKILQdlacvtrdrgdihnqltamcrKKEALNEE 829
Cdd:PRK02224  467 VETIEEDRErVEELEAELEDLEEEVEEVE-ERLERAEDLVEAEDRIERLEE---------------------RREDLEEL 524

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  830 LMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQvvidlhekdthrlnELLAALRSEKESLESVLFDTNTSLEATEERRSQ 909
Cdd:PRK02224  525 IAERRETIEEKRERAEELRERAAELEAEAEEKR--------------EAAAEAEEEAEEAREEVAELNSKLAELKERIES 590

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  910 LERdLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLlnaaraaeSDFNQKIANLQACAEEAAKRHGEEILQLRNAL 989
Cdd:PRK02224  591 LER-IRTLLAAIADAEDEIERLREKREALAELNDERRERL--------AEKRERKRELEAEFDEARIEEAREDKERAEEY 661

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 665394924  990 EKRMQQALQALQTAKDD-------------EIEKLQERLATLQAHLESLVQQHEEA 1032
Cdd:PRK02224  662 LEQVEEKLDELREERDDlqaeigaveneleELEELRERREALENRVEALEALYDEA 717
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
685-1252 2.44e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 65.83  E-value: 2.44e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  685 ESDNLINLLEKQKSDLEYDLdkLLLEKcdLQEKHEKLSNNSCSTSDELKSVQNCLQEAQEERKklRIQSVDQCNEIGELK 764
Cdd:PRK02224  139 EVNKLINATPSDRQDMIDDL--LQLGK--LEEYRERASDARLGVERVLSDQRGSLDQLKAQIE--EKEEKDLHERLNGLE 212

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  765 KELAILDKARLELETDNLSAGEKLKCLQL---EKEKILQDLACVTRDRGDIHNQLTAMCRKKEALNEELMRTRQRLEqtt 841
Cdd:PRK02224  213 SELAELDEEIERYEEQREQARETRDEADEvleEHEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLE--- 289

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  842 etnsRLNRNLEEMVKDVEekqvvidLHEKDTHRLNELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVRE 921
Cdd:PRK02224  290 ----ELEEERDDLLAEAG-------LDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERA 358

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  922 ESLKNHVARLQKELEQCQRKAQETKTQL------LNAARAAESDFNQKIANLQACAEEAAKRHGE----------EILQL 985
Cdd:PRK02224  359 EELREEAAELESELEEAREAVEDRREEIeeleeeIEELRERFGDAPVDLGNAEDFLEELREERDElrereaeleaTLRTA 438

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  986 RNALEKrmQQALQAL-------QTAKD----DEIEKLQERLATLQAHLESLVQQHEEalIRAESEKQQALLIAHRDKQAV 1054
Cdd:PRK02224  439 RERVEE--AEALLEAgkcpecgQPVEGsphvETIEEDRERVEELEAELEDLEEEVEE--VEERLERAEDLVEAEDRIERL 514

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1055 AERLEAVSRDLKTEQESLDRSRREAnardEKQRAAIAQLKDEMVQMRTKEEEHKIKLEEC---IRKQELQLSSLREERES 1131
Cdd:PRK02224  515 EERREDLEELIAERRETIEEKRERA----EELRERAAELEAEAEEKREAAAEAEEEAEEAreeVAELNSKLAELKERIES 590

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1132 LCRVSEELKmEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKysGSNKELRDHVKRVES 1211
Cdd:PRK02224  591 LERIRTLLA-AIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEAR--EDKERAEEYLEQVEE 667

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|.
gi 665394924 1212 AKRE--------QAR--AIEEALQKISNLEDTKNSLENERTRLSTILKETE 1252
Cdd:PRK02224  668 KLDElreerddlQAEigAVENELEELEELRERREALENRVEALEALYDEAE 718
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 654-1382 2.80e-10

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 65.76  E-value: 2.80e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   654 RSSRLREETISLREELNRVSLNRDLLEQQRIESDNLINLLEKQKSDLEYDLDKLLLEKCDLQEKHEKLSNNSCSTSDELK 733
Cdd:TIGR00618  160 AKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQ 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   734 SVQNCLQ---EAQEERKKLRIQSVDQCNEIGELKKELAILDKARLELEtdnlsageklkcLQLEKEKILQDLACVTRDRG 810
Cdd:TIGR00618  240 QSHAYLTqkrEAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERIN------------RARKAAPLAAHIKAVTQIEQ 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   811 DIHNQLTAMCRKKEALNEELMRTR--QRLEQTTETNSRLNRNL---EEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSE 885
Cdd:TIGR00618  308 QAQRIHTELQSKMRSRAKLLMKRAahVKQQSSIEEQRRLLQTLhsqEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQ 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   886 KESLE------SVLFDTNTSLEATEERRSQLERDLQEALVR---EESLKNHVARLQKELEQCQRKAQETKTQLLNAARAA 956
Cdd:TIGR00618  388 KTTLTqklqslCKELDILQREQATIDTRTSAFRDLQGQLAHakkQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQS 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   957 ESDFNQKIANLQACAEEAAKRHG------EEILQLRNALEKRMQQALQALQTAKDDE-----IEKLQERLATLQAHLESL 1025
Cdd:TIGR00618  468 LKEREQQLQTKEQIHLQETRKKAvvlarlLELQEEPCPLCGSCIHPNPARQDIDNPGpltrrMQRGEQTYAQLETSEEDV 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1026 VQQHEEALIRAESEKQQALLIAHrDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEE 1105
Cdd:TIGR00618  548 YHQLTSERKQRASLKEQMQEIQQ-SFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQD 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1106 EHKIKLEECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKegegfidSLRKELTDCRRQL 1185
Cdd:TIGR00618  627 LQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQ-------SEKEQLTYWKEML 699

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1186 ADSNIERdkysgsnKELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLS-TILKETENHFTKTTQDLNA 1264
Cdd:TIGR00618  700 AQCQTLL-------RELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQArTVLKARTEAHFNNNEEVTA 772

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1265 TKAQLQKAQvefaqkdeggkelqcKLVAEVELKERAQQELCQIKKQL-SDLEANLCATRQELGRARCQNNQEEHRFHARE 1343
Cdd:TIGR00618  773 ALQTGAELS---------------HLAAEIQFFNRLREEDTHLLKTLeAEIGQEIPSDEDILNLQCETLVQEEEQFLSRL 837

                          730       740       750
                   ....*....|....*....|....*....|....*....
gi 665394924  1344 QELAQRLEEGRGREKRLEDQKHNLEVCLADATQQIQELK 1382
Cdd:TIGR00618  838 EEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSD 876
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 874-1624 4.74e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.14  E-value: 4.74e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   874 RLNELLAALRSEKESLESVLFDTNTSLEATeerrsQLERDLQEALVREES-----LKNHVARLQKELEQCQ------RKA 942
Cdd:pfam15921   93 RLNESNELHEKQKFYLRQSVIDLQTKLQEM-----QMERDAMADIRRRESqsqedLRNQLQNTVHELEAAKclkedmLED 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   943 QETKTQLLNAARAAESDFNQKIANLQACAEEAAKRHGEEILQLRNALEKRMQQALQALQTAKDDEIEKLQERLATLQAHL 1022
Cdd:pfam15921  168 SNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQL 247

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1023 ESL---VQQHEEALIRAESEKQQALLIAHR-DKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMV 1098
Cdd:pfam15921  248 EALkseSQNKIELLLQQHQDRIEQLISEHEvEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVS 327

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1099 QMRTKEEEHKIKLEECIRKQELQL----SSLREERESLCRVSEEL-KMEIRLKEDRMESTNNELQDALRKSKEGEGFIDS 1173
Cdd:pfam15921  328 QLRSELREAKRMYEDKIEELEKQLvlanSELTEARTERDQFSQESgNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRD 407

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1174 LRKELT--DCRRQLADSNIERDKYSGSNKELRDHVKRVESAKREQARAIEEALQKISNL----EDTKNSLENERTRLsTI 1247
Cdd:pfam15921  408 TGNSITidHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLtaqlESTKEMLRKVVEEL-TA 486

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1248 LKETENHFTKTTQDLNATKAQLQKAQvefaqkdEGGKELQCKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQELGr 1327
Cdd:pfam15921  487 KKMTLESSERTVSDLTASLQEKERAI-------EATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMA- 558

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1328 arcQNNQEEHRFHAREQELAQRLEEGRGREKRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKr 1407
Cdd:pfam15921  559 ---EKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEK- 634

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1408 dtEQKLSSVVHTLRRIAGIQVDgsvnlSHRLLSPSRrfspsrscgdydnrsTSQCPDGPIDVDPDLVRKGVRNlmhQVAQ 1487
Cdd:pfam15921  635 --VKLVNAGSERLRAVKDIKQE-----RDQLLNEVK---------------TSRNELNSLSEDYEVLKRNFRN---KSEE 689

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1488 LEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEEKLKHRNDECQMLRE 1567
Cdd:pfam15921  690 METTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKE 769

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 665394924  1568 RLAQTEMQLAATSEENGQNEERLEKSRQQcskldneKRQLQEELAKVEGRASKLELQ 1624
Cdd:pfam15921  770 EKNKLSQELSTVATEKNKMAGELEVLRSQ-------ERRLKEKVANMEVALDKASLQ 819
mukB PRK04863
chromosome partition protein MukB;
868-1225 8.28e-10

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 64.59  E-value: 8.28e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  868 HEKDTHRLNELLAALRSEK-------ESLESVLFDTNTSLEATEERRSQLERDLQealvreeSLKNHVA------RLQKE 934
Cdd:PRK04863  277 HANERRVHLEEALELRRELytsrrqlAAEQYRLVEMARELAELNEAESDLEQDYQ-------AASDHLNlvqtalRQQEK 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  935 LEQCQRKAQETKTQLLNAARAAEsdfnqKIANLQACAEEAAKRHGEEILQLR----------NALEKR---MQQALQALQ 1001
Cdd:PRK04863  350 IERYQADLEELEERLEEQNEVVE-----EADEQQEENEARAEAAEEEVDELKsqladyqqalDVQQTRaiqYQQAVQALE 424

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1002 TAK------DDEIEKLQERLATLQAHLESL-----------------VQQHEEAL-----IRAESEKQQA------LLIA 1047
Cdd:PRK04863  425 RAKqlcglpDLTADNAEDWLEEFQAKEQEAteellsleqklsvaqaaHSQFEQAYqlvrkIAGEVSRSEAwdvareLLRR 504

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1048 HRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEmvqmrTKEEEHKIKLEECIRKQELQLSSLRE 1127
Cdd:PRK04863  505 LREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDE-----DELEQLQEELEARLESLSESVSEARE 579

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1128 ERESLCRVSEELKMEIRLKEDRmESTNNELQDALRKSKE--GEGFIDSlrKELTDCRRQLAdsniERDkysgsnKELRDH 1205
Cdd:PRK04863  580 RRMALRQQLEQLQARIQRLAAR-APAWLAAQDALARLREqsGEEFEDS--QDVTEYMQQLL----ERE------RELTVE 646

                         410       420
                  ....*....|....*....|
gi 665394924 1206 VKRVESAKREQARAIEEALQ 1225
Cdd:PRK04863  647 RDELAARKQALDEEIERLSQ 666
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1121-1667 1.81e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 63.01  E-value: 1.81e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1121 QLSSLREERESLCRVSEELKMEIRLKEDRMEstnNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNK 1200
Cdd:COG4913   243 ALEDAREQIELLEPIRELAERYAAARERLAE---LEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLD 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1201 ELRDHVKRVESAKREQ-ARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQK 1279
Cdd:COG4913   320 ALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEE 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1280 DEGGKELQCKL-VAEVELKER---AQQELCQIKKQLSDLEANLCATRQELGRArCQNNQEEHRFHAreqELAQ-RLEEGR 1354
Cdd:COG4913   400 LEALEEALAEAeAALRDLRRElreLEAEIASLERRKSNIPARLLALRDALAEA-LGLDEAELPFVG---ELIEvRPEEER 475

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1355 GR---EKRLEDQKHNLEV---CLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTEQKLSSVVHTL-------- 1420
Cdd:COG4913   476 WRgaiERVLGGFALTLLVppeHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFrawleael 555

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1421 -RRIAGIQVDGSVNLSHRllspsrRFSPSRSCGDYDNRSTSQCpDGPIDVDPDLV-----RKGVRNLMHQVAQLEREKDD 1494
Cdd:COG4913   556 gRRFDYVCVDSPEELRRH------PRAITRAGQVKGNGTRHEK-DDRRRIRSRYVlgfdnRAKLAALEAELAELEEELAE 628

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1495 YKSQLGAAKKQLQDAADQQLRC---------DAKLGKLQAMLRNLQEEKSNLETDRkmkiSAIQALEEKLKHrndecqmL 1565
Cdd:COG4913   629 AEERLEALEAELDALQERREALqrlaeyswdEIDVASAEREIAELEAELERLDASS----DDLAALEEQLEE-------L 697

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1566 RERLAQTEMQLAATSEENGQNEERLEKSRQQCskldnekRQLQEELAKVEGRASKLELQRVAmegdlTRLQMALQEKdcS 1645
Cdd:COG4913   698 EAELEELEEELDELKGEIGRLEKELEQAEEEL-------DELQDRLEAAEDLARLELRALLE-----ERFAAALGDA--V 763

                         570       580
                  ....*....|....*....|..
gi 665394924 1646 IRQMAERLENQNRALTQLEDRC 1667
Cdd:COG4913   764 ERELRENLEERIDALRARLNRA 785
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
821-1205 2.39e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 62.63  E-value: 2.39e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  821 RKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDL--HEKDTHRLNELLAALRSEKESLESvlfdTNT 898
Cdd:COG4913   610 AKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYswDEIDVASAEREIAELEAELERLDA----SSD 685

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  899 SLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLLNAARAAESDFNQKIANL--QACAEEAAK 976
Cdd:COG4913   686 DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERfaAALGDAVER 765

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  977 RHGEEILQLRNALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLES-------LVQQHEEALIRAESEKQQALliahr 1049
Cdd:COG4913   766 ELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESlpeylalLDRLEEDGLPEYEERFKELL----- 840

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1050 dkqavaerLEAVSRDLKTEQESLDRSRREANARdekqraaIAQLKDEMVQMRTKEEEHkIKLEecirKQELQLSSLREER 1129
Cdd:COG4913   841 --------NENSIEFVADLLSKLRRAIREIKER-------IDPLNDSLKRIPFGPGRY-LRLE----ARPRPDPEVREFR 900

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 665394924 1130 ESLCRVSEELKMEIRLKEDRMESTNNELQDALRksKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKELRDH 1205
Cdd:COG4913   901 QELRAVTSGASLFDEELSEARFAALKRLIERLR--SEEEESDRRWRARVLDVRNHLEFDAEEIDREDGEEVETYSS 974
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
811-1395 2.62e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 62.63  E-value: 2.62e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  811 DIHNQLTAMCRKKEALnEELMRTRQRLEQTTETNSRLNRnLEEMVkDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLE 890
Cdd:COG4913   239 RAHEALEDAREQIELL-EPIRELAERYAAARERLAELEY-LRAAL-RLWFAQRRLELLEAELEELRAELARLEAELERLE 315

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  891 svlfdtnTSLEATEERRSQLERDLQEA-LVREESLKNHVARLQKELEQCQRKAQETKTQLLN---AARAAESDFNQKIAN 966
Cdd:COG4913   316 -------ARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLEALLAAlglPLPASAEEFAALRAE 388

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  967 LQACAEEAAkrhgeeilQLRNALEKRMQQALQALQTAKDdEIEKLQERLATLQAH---LESLVQQHEEALIRAESEKQQA 1043
Cdd:COG4913   389 AAALLEALE--------EELEALEEALAEAEAALRDLRR-ELRELEAEIASLERRksnIPARLLALRDALAEALGLDEAE 459

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1044 LLIA---------HRDKQAVAER-LEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEE-----HK 1108
Cdd:COG4913   460 LPFVgelievrpeEERWRGAIERvLGGFALTLLVPPEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDpdslaGK 539

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1109 IKLEECIRKQELQLSSLREERESLCRVSEELKMEIR-LKEDRMESTNNElqdalRKSKEGEGFIDSlrkeltdcRRQLAD 1187
Cdd:COG4913   540 LDFKPHPFRAWLEAELGRRFDYVCVDSPEELRRHPRaITRAGQVKGNGT-----RHEKDDRRRIRS--------RYVLGF 606

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1188 SNIERdkysgsnkelrdhVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKetenhFTKTTQDLNATKA 1267
Cdd:COG4913   607 DNRAK-------------LAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAE-----YSWDEIDVASAER 668

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1268 QLQKAQVEFAQKDEGG---KELQCKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEHRFHAREQ 1344
Cdd:COG4913   669 EIAELEAELERLDASSddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR 748

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|.
gi 665394924 1345 ELAQRLEEGRGREKRLEDQKHNLEvcladatQQIQELKARLGGAEGRIRAL 1395
Cdd:COG4913   749 ALLEERFAAALGDAVERELRENLE-------ERIDALRARLNRAEEELERA 792
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 821-1683 3.74e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 62.30  E-value: 3.74e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   821 RKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQ-----VVIDLHEKDTHRLNELLAALRSEKESLESVLFD 895
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALeyyqlKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   896 TNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLLNAARAAESDFNQKIANLQACAEEAA 975
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   976 KRHGEEILQLRNALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAHRDKQAVA 1055
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1056 ERLEAVSR---DLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLE-ECIRKQELQLSSLREERES 1131
Cdd:pfam02463  409 LLLELARQledLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKkSEDLLKETQLVKLQEQLEL 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1132 LCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKELRDHVKRVES 1211
Cdd:pfam02463  489 LLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVR 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1212 AKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKELQCKLV 1291
Cdd:pfam02463  569 ALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGL 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1292 AEVELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEHRFHAREQELAQRLEEGRGREKRLEDQKHNLEVCL 1371
Cdd:pfam02463  649 RKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQ 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1372 ADATQQIQELKARLggaegriRALDEQLSCVELHKRDTEQKLSSVVHTLRRIAGIQVDGSVNLSHRLLSPSRRFSPSRSC 1451
Cdd:pfam02463  729 EAQDKINEELKLLK-------QKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEE 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1452 GDYDNRSTSQcpdgpidvdpdlvrkgvRNLMHQVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQ 1531
Cdd:pfam02463  802 ELRALEEELK-----------------EEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEIT 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1532 EEKSNLETDRKMKISAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEEL 1611
Cdd:pfam02463  865 KEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEE 944

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 665394924  1612 AKVEGRA-SKLELQRVAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLED----RCTALKSTVDQLKERLQK 1683
Cdd:pfam02463  945 ADEKEKEeNNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERleeeKKKLIRAIIEETCQRLKE 1021
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
980-1422 1.07e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.46  E-value: 1.07e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  980 EEILQLRNALEKRMQQALQAlqtakdDEIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQalliahrdKQAVAERLE 1059
Cdd:PRK03918  138 DAILESDESREKVVRQILGL------DDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEEL--------IKEKEKELE 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1060 AVSRDLKTEQESLDRSRRE-ANARDEKQR-AAIAQLKDEMVQMRTKEEEHKIKLEECIRKQELQLSSLREERESLCRVSE 1137
Cdd:PRK03918  204 EVLREINEISSELPELREElEKLEKEVKElEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVK 283

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1138 ELKmEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKELRDHVKRVESAKrEQA 1217
Cdd:PRK03918  284 ELK-ELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELE-ERH 361

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1218 RAIEEALQKISNLEDTKNSLEN-ERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKELQ-----CKLV 1291
Cdd:PRK03918  362 ELYEEAKAKKEELERLKKRLTGlTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKkakgkCPVC 441

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1292 A-------EVELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEHRFhaREQELAQRLEEgrgREKRLEdqK 1364
Cdd:PRK03918  442 GrelteehRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELI--KLKELAEQLKE---LEEKLK--K 514

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 665394924 1365 HNLEVcLADATQQIQELKARLGGAEGRIRALDEQLS----------CVELHKRDTEQKLSSVVHTLRR 1422
Cdd:PRK03918  515 YNLEE-LEKKAEEYEKLKEKLIKLKGEIKSLKKELEkleelkkklaELEKKLDELEEELAELLKELEE 581
PTZ00121 PTZ00121
MAEBL; Provisional
 901-1758 1.25e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.54  E-value: 1.25e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  901 EATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQ--RKAQETKTqlLNAARAAESdfNQKIANLQACAE----EA 974
Cdd:PTZ00121 1129 KAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEeaRKAEDAKK--AEAARKAEE--VRKAEELRKAEDarkaEA 1204

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  975 AKRHGEE--ILQLRNALEKRMQQALQALQTAKDDEIEklqerlatlqahleslVQQHEEALIRAESEKQQALLIAHRDKQ 1052
Cdd:PTZ00121 1205 ARKAEEErkAEEARKAEDAKKAEAVKKAEEAKKDAEE----------------AKKAEEERNNEEIRKFEEARMAHFARR 1268

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1053 AVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQmrtKEEEHKIKLEECIRKQElqlsSLREERESL 1132
Cdd:PTZ00121 1269 QAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAK---KADEAKKKAEEAKKKAD----AAKKKAEEA 1341

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1133 CRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRqlADsniERDKYSGSNKELRDHVKRVESA 1212
Cdd:PTZ00121 1342 KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK--AD---EAKKKAEEDKKKADELKKAAAA 1416

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1213 KREQARAIEEALQKISNLEDTKNSLEnertrlstilketenhftkttqdlnATKAQLQKAQVEFAQKDEGGKELQCKLVA 1292
Cdd:PTZ00121 1417 KKKADEAKKKAEEKKKADEAKKKAEE-------------------------AKKADEAKKKAEEAKKAEEAKKKAEEAKK 1471

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1293 EVELKERAQQelcqiKKQLSDLEANLCATRQELGRARCQNNQEEHRFHAREQELAQRLEEGRGRE--KRLEDQKHNLEVC 1370
Cdd:PTZ00121 1472 ADEAKKKAEE-----AKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEeaKKADEAKKAEEKK 1546

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1371 LADATQQIQELKARlggaegriraldEQLSCVELHKRDTEQKLSSvvhtLRRiagiqvdgsvnlshrllspsrrfspsrs 1450
Cdd:PTZ00121 1547 KADELKKAEELKKA------------EEKKKAEEAKKAEEDKNMA----LRK---------------------------- 1582

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1451 cgdydnrstsqcpdgpidvdPDLVRKGVRNLMHQVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNL 1530
Cdd:PTZ00121 1583 --------------------AEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKE 1642

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1531 QEEKSNLetdrkmkisaiqaleEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEE 1610
Cdd:PTZ00121 1643 AEEKKKA---------------EELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEEL 1707

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1611 LAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCSIRQMAE--RLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSE 1688
Cdd:PTZ00121 1708 KKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEakKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDE 1787

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 665394924 1689 TQLRGEI---KTLQKELSEQGHCSQANEDKLKLVQKSLQTAENEKRiltERLDSAQTNLNELRRSQQAQLDGN 1758
Cdd:PTZ00121 1788 EDEKRRMevdKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIK---EVADSKNMQLEEADAFEKHKFNKN 1857
PTZ00121 PTZ00121
MAEBL; Provisional
 583-1261 1.74e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.15  E-value: 1.74e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  583 VQKQQSEMGRADINSAFENLSSDYEKMQLNCGKLQKRIDSmEEDKKAVELeiqRILKDKNITELNLRSEEDRSSrlrEET 662
Cdd:PTZ00121 1235 AKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKA-EEARKADEL---KKAEEKKKADEAKKAEEKKKA---DEA 1307

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  663 ISLREELNRVSLNRDLLEQQRIESDNLINLLEKQKSDLEYDLDKLLLEKCDLQEKHEKLSNNSCSTSDELKSVQNCLQEA 742
Cdd:PTZ00121 1308 KKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKA 1387

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  743 QEERK--KLRIQSVDQCNEIGELKKELAILDKA-RLELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAM 819
Cdd:PTZ00121 1388 EEKKKadEAKKKAEEDKKKADELKKAAAAKKKAdEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAE 1467

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  820 CRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLESVLFDTNT- 898
Cdd:PTZ00121 1468 EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKk 1547

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  899 --SLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLLNAARAAESDFNQKIANLQACAEEAAK 976
Cdd:PTZ00121 1548 adELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK 1627

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  977 RHGE--EILQLRNALEKRMQQALQALQTAKDDEIEKLQE--------RLATLQAHLESLVQQHEEALIRAESEKQQALLI 1046
Cdd:PTZ00121 1628 AEEEkkKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEakkaeedkKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEEL 1707

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1047 ----AHRDKQAVAERLEAVSRDLKTEQ----ESLDRSRREANARDEKQRAAIAQLKDEmvqmRTKEEEHKIKLEECIRKQ 1118
Cdd:PTZ00121 1708 kkkeAEEKKKAEELKKAEEENKIKAEEakkeAEEDKKKAEEAKKDEEEKKKIAHLKKE----EEKKAEEIRKEKEAVIEE 1783

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1119 ElqlssLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEgfiDSLRKELTDCRR-QLADSN-IERDKYS 1196
Cdd:PTZ00121 1784 E-----LDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEME---DSAIKEVADSKNmQLEEADaFEKHKFN 1855

                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 665394924 1197 GSNKELRDHVKRVESAKREQARA--IEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQD 1261
Cdd:PTZ00121 1856 KNNENGEDGNKEADFNKEKDLKEddEEEIEEADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKD 1922
PRK11281 PRK11281
mechanosensitive channel MscK;
1492-1771 1.86e-08

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 59.93  E-value: 1.86e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1492 KDDYKSQLGAAKKQLQDAadqqlrcDAKLGKLQAMLRNLQEEKSNLETDRKMKISaIQALEEKLKHRNDECQMLRERLAQ 1571
Cdd:PRK11281   75 IDRQKEETEQLKQQLAQA-------PAKLRQAQAELEALKDDNDEETRETLSTLS-LRQLESRLAQTLDQLQNAQNDLAE 146

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1572 TEMQLAA--TSEENGQNE-----ERLEKSRQQCSKLDNEKR--------QLQEELAKVEGrasKLELQRVAMEGDlTRLQ 1636
Cdd:PRK11281  147 YNSQLVSlqTQPERAQAAlyansQRLQQIRNLLKGGKVGGKalrpsqrvLLQAEQALLNA---QNDLQRKSLEGN-TQLQ 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1637 MALQEKDCSIRQMAERLENQNRALTQL--EDRCTALKSTVDQLKERLQKSAVSETQLrgeiktLQKELSEQGHCSQ---- 1710
Cdd:PRK11281  223 DLLQKQRDYLTARIQRLEHQLQLLQEAinSKRLTLSEKTVQEAQSQDEAARIQANPL------VAQELEINLQLSQrllk 296

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 665394924 1711 ANEDKLKLVQKSLQTaeneKRILtERLDSAQTNLNE----LRRS----------QQA--QLDGNQRLQEQVTDLEVQ 1771
Cdd:PRK11281  297 ATEKLNTLTQQNLRV----KNWL-DRLTQSERNIKEqisvLKGSlllsrilyqqQQAlpSADLIEGLADRIADLRLE 368
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1007-1788 1.94e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.99  E-value: 1.94e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1007 EIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALLiahRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQ 1086
Cdd:pfam02463  177 KLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQL---KEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEI 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1087 RAAIAQLKDEMvqmRTKEEEHKI--KLEECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKS 1164
Cdd:pfam02463  254 ESSKQEIEKEE---EKLAQVLKEnkEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKEL 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1165 KEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRL 1244
Cdd:pfam02463  331 KKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLL 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1245 STILKETEnhftKTTQDLNATKAQLQKAQVEFAQKDEGGKELQCKLVAEVELKEraqQELCQIKKQLSDLEANLCATRQE 1324
Cdd:pfam02463  411 LELARQLE----DLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKL---LKDELELKKSEDLLKETQLVKLQ 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1325 LgrarcqnNQEEHRFHAREQELAQRLEEGRGREKRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDEQLSCVEL 1404
Cdd:pfam02463  484 E-------QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSAT 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1405 HKRDTEQKLSSVVHTLRRIAGIQVDGSVNLSHRLLSPSRRFSPSRSCGDYDNRSTSQCpdgpIDVDPDLVRKGVRNLMHQ 1484
Cdd:pfam02463  557 ADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLE----ADEDDKRAKVVEGILKDT 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1485 VAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEEKLKHRNDECQM 1564
Cdd:pfam02463  633 ELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEEL 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1565 LRERLAQTEMQLAATSEENGQNEERLEKSRQQCS--KLDNEKRQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEK 1642
Cdd:pfam02463  713 KKLKLEAEELLADRVQEAQDKINEELKLLKQKIDeeEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEK 792

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1643 DCSIRQMAERLENQNRaltqledrctALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEQGHCSQANEDKLKLVQKS 1722
Cdd:pfam02463  793 EEKLKAQEEELRALEE----------ELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEE 862

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 665394924  1723 LQTAENEKRILTERLDSAQtnLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQLRIAKWNQES 1788
Cdd:pfam02463  863 ITKEELLQELLLKEEELEE--QKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEE 926
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 814-1148 2.07e-08

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 59.37  E-value: 2.07e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   814 NQLTAMCRKKEALNEELMRTR-QRLEQttetnSRLNRNLEEMVKDVEEKQvviDLHEKDTHRLNEL--LAALRSEKESLE 890
Cdd:pfam17380  272 NQLLHIVQHQKAVSERQQQEKfEKMEQ-----ERLRQEKEEKAREVERRR---KLEEAEKARQAEMdrQAAIYAEQERMA 343

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   891 svlFDTNTSLE--ATEERRSQLERDLQEALVREESLKNHVARLQKELEQcqrkAQETKTQLLNAARaaesdfnqKIANLQ 968
Cdd:pfam17380  344 ---MERERELEriRQEERKRELERIRQEEIAMEISRMRELERLQMERQQ----KNERVRQELEAAR--------KVKILE 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   969 ACAEEAAKRHGEEILQLRNALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEE---ALIRAESEKQQALL 1045
Cdd:pfam17380  409 EERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEErkrKKLELEKEKRDRKR 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1046 IAHRDKQAVAERLEAVSRDLKTEQesldRSRREANARDEKQRAAIAqlkdEMVQMRTKEEEHK--IKLEECIRKQElQLS 1123
Cdd:pfam17380  489 AEEQRRKILEKELEERKQAMIEEE----RKRKLLEKEMEERQKAIY----EEERRREAEEERRkqQEMEERRRIQE-QMR 559

                          330       340
                   ....*....|....*....|....*
gi 665394924  1124 SLREERESLCRVSEELKMEIRLKED 1148
Cdd:pfam17380  560 KATEERSRLEAMEREREMMRQIVES 584
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 211-1038 2.12e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 59.70  E-value: 2.12e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   211 AGAAELCRKLEEEHQRCEQIvaqnsalRQQLEESNRTNEALTNDLQKLTNDwaslrDELLIKEDEFKEEEQAFKDYynse 290
Cdd:TIGR02169  163 AGVAEFDRKKEKALEELEEV-------EENIERLDLIIDEKRQQLERLRRE-----REKAERYQALLKEKREYEGY---- 226

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   291 hnRLLKMWREVVAVKRSFKEMQTAMKAEVAKMGQEINCVGKDINGSNATVAFAVQQAKRAADDELKQsqrsndeLQNQLA 370
Cdd:TIGR02169  227 --ELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLR-------VKEKIG 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   371 TLKVQYESARHEIMERDQRLLELMNQLKKLE-DRCAQAESQAALASRYSDEIERLNNSMREIA--QAVVQDAENADREAD 447
Cdd:TIGR02169  298 ELEAEIASLERSIAEKERELEDAEERLAKLEaEIDKLLAEIEELEREIEEERKRRDKLTEEYAelKEELEDLRAELEEVD 377

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   448 AEVTGGVMQHMHLTRDAASVVGGAGGAGSTAGGGGKSPRRNSTRasQAFAEGTISAVQAALHKYQLALHDMQVKFQNTSE 527
Cdd:TIGR02169  378 KEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEE--LADLNAAIAGIEAKINELEEEKEDKALEIKKQEW 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   528 TLRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSELLQERESLQRGLDDIRVQKQQSEMGRADINSAFENLSSDYE 607
Cdd:TIGR02169  456 KLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGE 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   608 KMQLNC-GKLQKRIDSMEEDKKAVELEIQRILKDKNITELN------LRSEEDRSSRLREETI----------------- 663
Cdd:TIGR02169  536 RYATAIeVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATflplnkMRDERRDLSILSEDGVigfavdlvefdpkyepa 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   664 ---------------SLREELNR---VSLNRDLLEQ--------QRIESDNLINLLEKQKS-DLEYDLDKLLLEKCDLQE 716
Cdd:TIGR02169  616 fkyvfgdtlvvedieAARRLMGKyrmVTLEGELFEKsgamtggsRAPRGGILFSRSEPAELqRLRERLEGLKRELSSLQS 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   717 KHEKLSNNSCSTSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDKARLELETDNLSAGEKLKCLQLEKE 796
Cdd:TIGR02169  696 ELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLH 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   797 KILQDLACVTRDrgDIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLN 876
Cdd:TIGR02169  776 KLEEALNDLEAR--LSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIE 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   877 ELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEalvreesLKNHVARLQKELEQCQRKAQETKTQL--LNAAR 954
Cdd:TIGR02169  854 KEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDE-------LEAQLRELERKIEELEAQIEKKRKRLseLKAKL 926

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   955 AAESDFNQKIANLQACAEE--AAKRHGEEILQLRNALEKRMqQALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEEA 1032
Cdd:TIGR02169  927 EALEEELSEIEDPKGEDEEipEEELSLEDVQAELQRVEEEI-RALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAI 1005


                   ....*.
gi 665394924  1033 LIRAES 1038
Cdd:TIGR02169 1006 LERIEE 1011
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 874-1089 2.70e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.24  E-value: 2.70e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  874 RLNELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQrkaQETKTQLLNAA 953
Cdd:COG4942    38 ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK---EELAELLRALY 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  954 RAAESDFNQKIANlQACAEEAAKRhgeeiLQLRNALEKRMQQALQALQTAKdDEIEKLQERLATLQAHLESLVQQHEE-- 1031
Cdd:COG4942   115 RLGRQPPLALLLS-PEDFLDAVRR-----LQYLKYLAPARREQAEELRADL-AELAALRAELEAERAELEALLAELEEer 187

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 665394924 1032 -ALIRAESEKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAA 1089
Cdd:COG4942   188 aALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 501-1632 3.13e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 59.03  E-value: 3.13e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   501 ISAVQAALHKYQLALHDMQVKFQNTSE--TLRTTKAQLET-----SEGTKQLLTTKMQQLTEKLDSSNSKLSE------- 566
Cdd:pfam01576   14 LQKVKERQQKAESELKELEKKHQQLCEekNALQEQLQAETelcaeAEEMRARLAARKQELEEILHELESRLEEeeersqq 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   567 LLQERESLQRGLDDIRVQKQQSEMGRadinsafenlssdyEKMQLNCGKLQKRIDSMEEDKKAVELEIQRILKDKNITEL 646
Cdd:pfam01576   94 LQNEKKKMQQHIQDLEEQLDEEEAAR--------------QKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   647 NLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQRIESDNLINLLEKQKSDLEYDLDKLLLEKCDLQEKHEKLSNNSC 726
Cdd:pfam01576  160 RISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLA 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   727 STSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQDLACVT 806
Cdd:pfam01576  240 KKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTTAAQQ 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   807 RDRGDIHNQLTAMcrkKEALNEElmrTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEK 886
Cdd:pfam01576  320 ELRSKREQEVTEL---KKALEEE---TRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAEL 393

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   887 ESLESVLFDtntsleaTEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAqETKTQLLNAARAAESDFNQKIAN 966
Cdd:pfam01576  394 RTLQQAKQD-------SEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSEL-ESVSSLLNEAEGKNIKLSKDVSS 465

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   967 LQACAEEAAKRHGEEILQlRNALEKRMQQaLQALQTAKDDEIEKLQERLATLQAHLESLVQQHEEALIRAESEkqqalli 1046
Cdd:pfam01576  466 LESQLQDTQELLQEETRQ-KLNLSTRLRQ-LEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEED------- 536

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1047 ahrdkQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECIRKQELQLSSLR 1126
Cdd:pfam01576  537 -----AGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLA 611

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1127 EERESLCRVSEE---LKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDcrrqladsnierdkYSGSNKELR 1203
Cdd:pfam01576  612 EEKAISARYAEErdrAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMED--------------LVSSKDDVG 677

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1204 DHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTilketenhftkttqDLNATKAQLQKaqvEFAQKDEGG 1283
Cdd:pfam01576  678 KNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEV--------------NMQALKAQFER---DLQARDEQG 740

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1284 KELQCKLV-----AEVELK-ERAQQELC-----QIKKQLSDLEANLCATrqelGRARCQNNQEEHRFHAREQELAQRLEE 1352
Cdd:pfam01576  741 EEKRRQLVkqvreLEAELEdERKQRAQAvaakkKLELDLKELEAQIDAA----NKGREEAVKQLKKLQAQMKDLQRELEE 816

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1353 GRGREKrledqkhnlevclaDATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTEQKLSSVVHTLrriagiqvdGSV 1432
Cdd:pfam01576  817 ARASRD--------------EILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEI---------ASG 873

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1433 NLSHRLLSPSRRFSPSRSCGDYDNRSTSQCpdgpidvDPDLVRKGVRNLMHQVAQLEREKDDYKSQLgaakkQLQDAADQ 1512
Cdd:pfam01576  874 ASGKSALQDEKRRLEARIAQLEEELEEEQS-------NTELLNDRLRKSTLQVEQLTTELAAERSTS-----QKSESARQ 941

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1513 QLRCDAKLGKLQamlrnLQEEKSNLETDRKMKISAIQA----LEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEE 1588
Cdd:pfam01576  942 QLERQNKELKAK-----LQEMEGTVKSKFKSSIAALEAkiaqLEEQLEQESRERQAANKLVRRTEKKLKEVLLQVEDERR 1016

                         1130      1140      1150      1160
                   ....*....|....*....|....*....|....*....|....
gi 665394924  1589 RLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQRVAMEGDL 1632
Cdd:pfam01576 1017 HADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQREL 1060
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 90-918 4.51e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.53  E-value: 4.51e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924    90 ALLRQNQELRQRLADESHSYRRRLDTYKQAQHNQANLVSRLQSKIQQYRQRCSDLEermhetikptagvgpklttgpTNQ 169
Cdd:TIGR02168  260 AELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLE---------------------RQL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   170 VLCSTSLTLGQSSLPCSSSLDSPPPSCSRDYVDDVlvtgggagaAELCRKLEEEHQRCEQIVAQNSALRQQLEESNRTNE 249
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEEL---------ESLEAELEELEAELEELESRLEELEEQLETLRSKVA 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   250 ALTNDLQKLTNDWASLRDELLIKEDEFKEEEQAfkdyyNSEHNRLLKmwrevvavkrsfkemqtamKAEVAKMGQEINCV 329
Cdd:TIGR02168  390 QLELQIASLNNEIERLEARLERLEDRRERLQQE-----IEELLKKLE-------------------EAELKELQAELEEL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   330 GKDINGSNATVAFAVQQAKRaADDELKQSQRSNDELQNQLATLkvqyeSARHEIMERDQRLLE--------LMNQLKKLE 401
Cdd:TIGR02168  446 EEELEELQEELERLEEALEE-LREELEEAEQALDAAERELAQL-----QARLDSLERLQENLEgfsegvkaLLKNQSGLS 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   402 DRCAQAESQAALASRYSDEIErlnNSMREIAQAVVQDAENADREA---DAEVTGGVMQHMHLTRDAASVVGGAGGAGSTA 478
Cdd:TIGR02168  520 GILGVLSELISVDEGYEAAIE---AALGGRLQAVVVENLNAAKKAiafLKQNELGRVTFLPLDSIKGTEIQGNDREILKN 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   479 GGGGKSPrRNSTRASQAFAEGTISAVQAALH---KYQLALHdmQVKFQNTSETLRTTKAQLETSEGTkqllttkmqqLTE 555
Cdd:TIGR02168  597 IEGFLGV-AKDLVKFDPKLRKALSYLLGGVLvvdDLDNALE--LAKKLRPGYRIVTLDGDLVRPGGV----------ITG 663

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   556 KLDSSNSKLSELLQERESLQRGLDDIRVQKQQSEMGRADINSAFENLSSDYEKMQLNCGKLQKRIDSMEEDKKAVELEIQ 635
Cdd:TIGR02168  664 GSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   636 RILKDKNITELNLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQRIESDNLINLLEKQKSDLEYDLDKLLLEKCDLQ 715
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR 823

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   716 EKHEKLSNNSCSTSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDKARLELEtdnlsagEKLKCLQLEK 795
Cdd:TIGR02168  824 ERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLE-------EALALLRSEL 896

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   796 EKILQDLACVTRDRGDIHNQLTAMCRKKEALNEELMRTRQRLEQTTET-NSRLNRNLEEMVKDVEEKqvvidlhEKDTHR 874
Cdd:TIGR02168  897 EELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERlSEEYSLTLEEAEALENKI-------EDDEEE 969

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*..
gi 665394924   875 LNELLAALRSEKESLESVLFDTNTSLEATEERRSQLER---DLQEAL 918
Cdd:TIGR02168  970 ARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAqkeDLTEAK 1016
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1509-1731 5.69e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 57.08  E-value: 5.69e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1509 AADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEE 1588
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1589 RLEKSRQQCSKLDNE--KRQLQEELAKVEGRASKLELQRVAMegDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDR 1666
Cdd:COG4942    98 ELEAQKEELAELLRAlyRLGRQPPLALLLSPEDFLDAVRRLQ--YLKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 665394924 1667 CTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEQGHCSQANEDKLKLVQKSLQTAENEKR 1731
Cdd:COG4942   176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1545-1925 6.47e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.16  E-value: 6.47e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1545 ISAIQALEEKLKHRNDECQMLRERLAQTEMQLaatsEENGQNEERLEKSRQQCSKLDNEKRQLQE-ELAKVEGRASKLEL 1623
Cdd:TIGR02169  162 IAGVAEFDRKKEKALEELEEVEENIERLDLII----DEKRQQLERLRREREKAERYQALLKEKREyEGYELLKEKEALER 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1624 QRVAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKStvdqlkerlqksavsetqlrGEIKTLQKELS 1703
Cdd:TIGR02169  238 QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE--------------------EEQLRVKEKIG 297

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1704 E-QGHCSQAnEDKLKLVQKSLQTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQL--- 1779
Cdd:TIGR02169  298 ElEAEIASL-ERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELeev 376

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1780 --RIAKWNQESggdkdltngNGGGNGEEELSRQLKSSQREKSELRSKLQTLQDKVKQLECDRKSKFSGGNAYDrAEKSNS 1857
Cdd:TIGR02169  377 dkEFAETRDEL---------KDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELE-EEKEDK 446

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 665394924  1858 FYGGAAESGEFDSNRYDVgggnagggsfncgldhSVIEQETRDLRLKVRRLETLLAEKESELARCKAR 1925
Cdd:TIGR02169  447 ALEIKKQEWKLEQLAADL----------------SKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQ 498
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1126-1842 7.73e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.77  E-value: 7.73e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1126 REERESLCRVSEELKMEIRLKEDRMESTNNELQDALRkskegegfIDSLRKELTDcrrqladsnIERDKYSGSNKELRDH 1205
Cdd:TIGR02169  176 LEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--------YQALLKEKRE---------YEGYELLKEKEALERQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1206 VKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLST-ILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGK 1284
Cdd:TIGR02169  239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKkIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1285 ELQCKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQELGRARcqnnqeehrfhAREQELAQRLEE-----------G 1353
Cdd:TIGR02169  319 DAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELK-----------EELEDLRAELEEvdkefaetrdeL 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1354 RGREKRLEDQKHNLE----------VCLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTEQKLSSVVHTLRRI 1423
Cdd:TIGR02169  388 KDYREKLEKLKREINelkreldrlqEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKY 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1424 AgiqvDGSVNLSHRLLSPSRRFSPSRSCGDYDNRSTSQCPDGPIDVDP--DLVRKGVRNLMHQVAQLEREKDDYKSQLGA 1501
Cdd:TIGR02169  468 E----QELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAveEVLKASIQGVHGTVAQLGSVGERYATAIEV 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1502 AKKQLQDAADQQLRCDAK------------------LGKLQAMLRNLQEEKSN---------LETDRKMKISAIQALEEK 1554
Cdd:TIGR02169  544 AAGNRLNNVVVEDDAVAKeaiellkrrkagratflpLNKMRDERRDLSILSEDgvigfavdlVEFDPKYEPAFKYVFGDT 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1555 LKHRNDEC---QMLRERLAQTEMQL---------AATSEENGQN-----EERLEKSRQQCSKLDNEKRQLQEELAKVEGR 1617
Cdd:TIGR02169  624 LVVEDIEAarrLMGKYRMVTLEGELfeksgamtgGSRAPRGGILfsrsePAELQRLRERLEGLKRELSSLQSELRRIENR 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1618 ASKLELQRVAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKT 1697
Cdd:TIGR02169  704 LDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALND 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1698 LQKELSEQghcsqanedKLKLVQKSLQTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALES 1777
Cdd:TIGR02169  784 LEARLSHS---------RIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEK 854

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 665394924  1778 QLRIAKWNQEsggdKDLTNGNGGGNGEEELSRQLKSSQREKSELRSKLQTLQDKVKQLECDRKSK 1842
Cdd:TIGR02169  855 EIENLNGKKE----ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 874-1187 7.77e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 58.04  E-value: 7.77e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  874 RLNELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKtQLLNAA 953
Cdd:COG3096   344 RQQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQ-QAVQAL 422

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  954 RAAesdfnQKIANLQACAEEAAKRHgeeilqlrnalekrmQQALQALQTAKDDEIEKLQERLATLQAHleslVQQHEEAL 1033
Cdd:COG3096   423 EKA-----RALCGLPDLTPENAEDY---------------LAAFRAKEQQATEEVLELEQKLSVADAA----RRQFEKAY 478

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1034 -----IRAESEKQQA------LLIAHRDKQAVAERLEAVSRDLKtEQESLDRSRREAnardEKQRAAIAQLKDEMVQMRT 1102
Cdd:COG3096   479 elvckIAGEVERSQAwqtareLLRRYRSQQALAQRLQQLRAQLA-ELEQRLRQQQNA----ERLLEEFCQRIGQQLDAAE 553

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1103 KEEEHKIKLEECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDRmESTNNELQDALRKSKE--GEGFIDSlrKELTD 1180
Cdd:COG3096   554 ELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAAR-APAWLAAQDALERLREqsGEALADS--QEVTA 630


                  ....*..
gi 665394924 1181 CRRQLAD 1187
Cdd:COG3096   631 AMQQLLE 637
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
783-1025 8.95e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.62  E-value: 8.95e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  783 SAGEKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAMCRKKEALN----------------EELMRTRQRLEQTTETNSR 846
Cdd:COG4913   607 DNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlaeyswdeidvasaeREIAELEAELERLDASSDD 686

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  847 LnRNLEEMVKDVEEKqvvIDLHEKDTHRLNELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVREESLKN 926
Cdd:COG4913   687 L-AALEEQLEELEAE---LEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDA 762

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  927 HVARLQKELEQCQRKAQETKTQLLNAARAAESDFNQK----IANLQACAEEAA------KRHGEEIL-----QLRNALEK 991
Cdd:COG4913   763 VERELRENLEERIDALRARLNRAEEELERAMRAFNREwpaeTADLDADLESLPeylallDRLEEDGLpeyeeRFKELLNE 842

                         250       260       270
                  ....*....|....*....|....*....|....
gi 665394924  992 RMQQALQALQTAKDDEIEKLQERLATLQAHLESL 1025
Cdd:COG4913   843 NSIEFVADLLSKLRRAIREIKERIDPLNDSLKRI 876
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
973-1664 9.50e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.62  E-value: 9.50e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  973 EAAKRHGEEILQLRNALEKRMQQ--ALQALQtAKDDEIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAHRD 1050
Cdd:COG4913   228 DALVEHFDDLERAHEALEDAREQieLLEPIR-ELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELAR 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1051 KQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQ-RAAIAQLKDEMVQMRTKEEEhkikLEECIRKQELQLSSLREER 1129
Cdd:COG4913   307 LEAELERLEARLDALREELDELEAQIRGNGGDRLEQlEREIERLERELEERERRRAR----LEALLAALGLPLPASAEEF 382

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1130 ESLCRVSEELKMEIrlkEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQlaDSNIERDkysgsNKELRDHVKRV 1209
Cdd:COG4913   383 AALRAEAAALLEAL---EEELEALEEALAEAEAALRDLRRELRELEAEIASLERR--KSNIPAR-----LLALRDALAEA 452

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1210 ESAKREQARAIEEALQKISNLEDTKNSLENE-RTRLSTILKEtENHFTKTTQDLNATK--AQLQKAQVEFAQKDEGGKEL 1286
Cdd:COG4913   453 LGLDEAELPFVGELIEVRPEEERWRGAIERVlGGFALTLLVP-PEHYAAALRWVNRLHlrGRLVYERVRTGLPDPERPRL 531

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1287 QCK-LVAEVELKE-RAQQELcqikkqlsdleanlcatRQELGR----ARCQNNQEEHRFHAREQELAQRLEEGRGREKRL 1360
Cdd:COG4913   532 DPDsLAGKLDFKPhPFRAWL-----------------EAELGRrfdyVCVDSPEELRRHPRAITRAGQVKGNGTRHEKDD 594

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1361 EDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTEQKLssvvHTLRRIAGIQVDgsvnlshrlls 1440
Cdd:COG4913   595 RRRIRSRYVLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERR----EALQRLAEYSWD----------- 659

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1441 psrrfspsrscgdydnrstsqcpdgpiDVDPDLVRKGVRNLMHQVAQLEREKDDY---KSQLGAAKKQLQDAADQQLRCD 1517
Cdd:COG4913   660 ---------------------------EIDVASAEREIAELEAELERLDASSDDLaalEEQLEELEAELEELEEELDELK 712

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1518 AKLGKLQAMLRNLQEE----KSNLETDRKMKISAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEERLEKS 1593
Cdd:COG4913   713 GEIGRLEKELEQAEEEldelQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERA 792

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1594 RQQ-CSKLDNEKRQL------------------QEELAKVEGRAskLELQRVAMEGDLTRLQMALQEkdcSIRQMAERLE 1654
Cdd:COG4913   793 MRAfNREWPAETADLdadleslpeylalldrleEDGLPEYEERF--KELLNENSIEFVADLLSKLRR---AIREIKERID 867

                         730
                  ....*....|
gi 665394924 1655 NQNRALTQLE 1664
Cdd:COG4913   868 PLNDSLKRIP 877
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1489-1763 1.09e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 57.36  E-value: 1.09e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1489 EREKDDYKSQLGAAKKQLQDAADQQLRcdAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEEKL---KHRNDECQML 1565
Cdd:PRK02224  179 ERVLSDQRGSLDQLKAQIEEKEEKDLH--ERLNGLESELAELDEEIERYEEQREQARETRDEADEVLeehEERREELETL 256

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1566 RERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCS 1645
Cdd:PRK02224  257 EAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVA 336

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1646 IRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEqghcsqaNEDKLKLVQKSLQT 1725
Cdd:PRK02224  337 AQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEE-------LRERFGDAPVDLGN 409

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 665394924 1726 AENEKRILTERLDSAQTNLNELR---RSQQAQLDGNQRLQE 1763
Cdd:PRK02224  410 AEDFLEELREERDELREREAELEatlRTARERVEEAEALLE 450
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1479-1835 1.12e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 57.27  E-value: 1.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1479 RNLMHQVAQLEREKDDYKSQLGAAKKQLQDAADQQlrcdAKLGKLQAMLrnlqEEKSNLETDRKMKISAIQALEEKLKHR 1558
Cdd:COG3096   281 RELSERALELRRELFGARRQLAEEQYRLVEMAREL----EELSARESDL----EQDYQAASDHLNLVQTALRQQEKIERY 352

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1559 NDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDN-----------------EKRQLQEELAKVEGRASKL 1621
Cdd:COG3096   353 QEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSqladyqqaldvqqtraiQYQQAVQALEKARALCGLP 432

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1622 ELQRVAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLE-------------DRCTALKSTVDQLKE--RLQKSAV 1686
Cdd:COG3096   433 DLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEkayelvckiagevERSQAWQTARELLRRyrSQQALAQ 512

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1687 SETQLRGEIKTLQKELSEQGHCSQANEDKLKLVQKSLQTAEN------EKRILTERLDSAQTNLNELRRSQQAQLDgnqR 1760
Cdd:COG3096   513 RLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLDAAEEleellaELEAQLEELEEQAAEAVEQRSELRQQLE---Q 589

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 665394924 1761 LQEQVTDLEVQRSA-LESQLRIAKWNQESGgdKDLTNGNGGGNGEEELSRQLKSSQREKSELRSKLQTLQDKVKQL 1835
Cdd:COG3096   590 LRARIKELAARAPAwLAAQDALERLREQSG--EALADSQEVTAAMQQLLEREREATVERDELAARKQALESQIERL 663
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
617-1244 1.39e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 57.00  E-value: 1.39e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  617 QKRIDSMEEDKKAVELEIQRILK-------DKN----ITELNLRSEEDRSSRLREETISLREELNrvslnrdllEQQRIE 685
Cdd:PRK03918  134 QGEIDAILESDESREKVVRQILGlddyenaYKNlgevIKEIKRRIERLEKFIKRTENIEELIKEK---------EKELEE 204

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  686 SDNLINLLEKQKSDLEYDLDKLLLEKCDLQEKHEKLSNnscsTSDELKSVQNCLQEAQEERKKLRIQsvdqcneIGELKK 765
Cdd:PRK03918  205 VLREINEISSELPELREELEKLEKEVKELEELKEEIEE----LEKELESLEGSKRKLEEKIRELEER-------IEELKK 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  766 ELAILDKARLELETDNLSAGEKLKcLQLEKEKILQDLACVTRDRGDIHNQLTAMCRKKEALNEElmrtRQRLEQTTETNS 845
Cdd:PRK03918  274 EIEELEEKVKELKELKEKAEEYIK-LSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEK----EERLEELKKKLK 348

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  846 RLNRNLEEMVKDVEEKQvvidlhekDTHRLNELLAALRSEKESLEsvLFDTNTSLEATEERRSQLERDLQEALVREESLK 925
Cdd:PRK03918  349 ELEKRLEELEERHELYE--------EAKAKKEELERLKKRLTGLT--PEKLEKELEELEKAKEEIEEEISKITARIGELK 418

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  926 NHVARLQKELEQCQRKAQETKTqllnaaraaesdfnqkianlqaCAEEAAKRHGEEILQLRNALEKRMQQALQALqTAKD 1005
Cdd:PRK03918  419 KEIKELKKAIEELKKAKGKCPV----------------------CGRELTEEHRKELLEEYTAELKRIEKELKEI-EEKE 475

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1006 DEIEKLQERLATLQAHLESLVQQHE--EALIRAESEKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARD 1083
Cdd:PRK03918  476 RKLRKELRELEKVLKKESELIKLKElaEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELK 555

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1084 EKQRAAIAQLKDemVQMRTKEEEHKIKLE--ECIRKQELQLSSLREERESLCRVSEELKmEIRLKEDRMESTNNELQDAL 1161
Cdd:PRK03918  556 KKLAELEKKLDE--LEEELAELLKELEELgfESVEELEERLKELEPFYNEYLELKDAEK-ELEREEKELKKLEEELDKAF 632

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1162 RKSKEGEGFIDSLRKELTDCRRQLADSNIERDK---------YSG------SNKELRDHVKRVESAKREQARAIEEALQK 1226
Cdd:PRK03918  633 EELAETEKRLEELRKELEELEKKYSEEEYEELReeylelsreLAGlraeleELEKRREEIKKTLEKLKEELEEREKAKKE 712

                         650
                  ....*....|....*...
gi 665394924 1227 ISNLEDTKNSLENERTRL 1244
Cdd:PRK03918  713 LEKLEKALERVEELREKV 730
PTZ00121 PTZ00121
MAEBL; Provisional
 853-1413 1.58e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.07  E-value: 1.58e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  853 EMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLEsvlfDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQ 932
Cdd:PTZ00121 1281 DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKAD----EAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAA 1356

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  933 KELEQCQRKAQETKTQLLNAARAAE-----SDFNQKIANLQACAEEAaKRHGEEILQLRNALEKRMQQALQALQTAKDDE 1007
Cdd:PTZ00121 1357 DEAEAAEEKAEAAEKKKEEAKKKADaakkkAEEKKKADEAKKKAEED-KKKADELKKAAAAKKKADEAKKKAEEKKKADE 1435

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1008 IEKLQERlatlqahleslVQQHEEALIRAESEKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQR 1087
Cdd:PTZ00121 1436 AKKKAEE-----------AKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKK 1504

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1088 AAIAQLKDEmvQMRTKEEEHKI----KLEECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRK 1163
Cdd:PTZ00121 1505 AAEAKKKAD--EAKKAEEAKKAdeakKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRK 1582

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1164 SKEGegfidslrKELTDCRRQLADSNIERDKYSGSNKELRDHVKRVesaKREQARAIEEALQKIsnlEDTKNSLENERTR 1243
Cdd:PTZ00121 1583 AEEA--------KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKI---KAEELKKAEEEKKKV---EQLKKKEAEEKKK 1648

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1244 LSTILKETENHFTKTTQDlnATKAQLQKAQVEFAQKDEggkELQCKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQ 1323
Cdd:PTZ00121 1649 AEELKKAEEENKIKAAEE--AKKAEEDKKKAEEAKKAE---EDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1324 ElgrarcqnnQEEHRFHAREQELAQRLEEGRGREKRLEDQKHNlevcladatqQIQELKARLGGAEGRIRALDEQLSCVE 1403
Cdd:PTZ00121 1724 A---------EEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKK----------KIAHLKKEEEKKAEEIRKEKEAVIEEE 1784

                         570
                  ....*....|
gi 665394924 1404 LHKRDTEQKL 1413
Cdd:PTZ00121 1785 LDEEDEKRRM 1794
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1212-1821 2.06e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.48  E-value: 2.06e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1212 AKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKELQCKLV 1291
Cdd:COG1196   233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1292 AEVELKERAQQELCQIKKQLSDLEANL---CATRQELGRARCQNNQEEHRFHAREQELAQRLEEGRGREKRLEDQKHNLE 1368
Cdd:COG1196   313 ELEERLEELEEELAELEEELEELEEELeelEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1369 VCLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTEQKLSSVVHTLRRIagiqvdgsvnlshrllspsrrfsps 1448
Cdd:COG1196   393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA------------------------- 447

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1449 rscgdydnrstsqcpdgpidvdpdlvRKGVRNLMHQVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLR 1528
Cdd:COG1196   448 --------------------------AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA 501

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1529 NLQEEksnLETDRKMKISAIQALEEKLKHRNDECQMLRERLAQTEmqLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQ 1608
Cdd:COG1196   502 DYEGF---LEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA--LAAALQNIVVEDDEVAAAAIEYLKAAKAGRATF 576

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1609 EELAKVEGRASKLELQRVAMEGDLTRLQMALQEkdcsirqmAERLENQNRALTQLEDrcTALKSTVDQLKERLQKSAVSE 1688
Cdd:COG1196   577 LPLDKIRARAALAAALARGAIGAAVDLVASDLR--------EADARYYVLGDTLLGR--TLVAARLEAALRRAVTLAGRL 646

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1689 TQLRGEIKTLQKELSEQGHCSQANEDKLKLVQKSLQTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQVTDL 1768
Cdd:COG1196   647 REVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEAL 726

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|...
gi 665394924 1769 EVQRSALESQLRIAKWNQESGGDKDLTNGNGGGNGEEELSRQLKSSQREKSEL 1821
Cdd:COG1196   727 EEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1523-1777 2.09e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 56.18  E-value: 2.09e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1523 LQAMLRNLQEEksNLETDRKMKISAIQALEEKLKHrndecqmLRERLAQTEMQLAATSEENG--QNEERLEKSRQQCSKL 1600
Cdd:COG3206   154 ANALAEAYLEQ--NLELRREEARKALEFLEEQLPE-------LRKELEEAEAALEEFRQKNGlvDLSEEAKLLLQQLSEL 224

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1601 DNEKRQLQEELAKVEGRASKLELQRVAMEGDLTRLQmalqekdcsirqmaerlenQNRALTQLEDRCTALKSTVDQLKER 1680
Cdd:COG3206   225 ESQLAEARAELAEAEARLAALRAQLGSGPDALPELL-------------------QSPVIQQLRAQLAELEAELAELSAR 285

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1681 LQKSAVSETQLRGEIKTLQKELSEQghcsqanedklklVQKSLQTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQR 1760
Cdd:COG3206   286 YTPNHPDVIALRAQIAALRAQLQQE-------------AQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAE 352

                         250
                  ....*....|....*..
gi 665394924 1761 LQEQVTDLEVQRSALES 1777
Cdd:COG3206   353 LRRLEREVEVARELYES 369
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1200-1683 3.12e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 55.69  E-value: 3.12e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1200 KELRDHVKRVESAkREQARAIEEALQKIS--NLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFA 1277
Cdd:COG4913   255 EPIRELAERYAAA-RERLAELEYLRAALRlwFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIR 333

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1278 QkdEGGKELqcklvaevelkERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEHRFHAREQELAQRLEEGRGRE 1357
Cdd:COG4913   334 G--NGGDRL-----------EQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEEL 400

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1358 KRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDEQLscVELhKRDTEQKLSSVVHTLrRIAG--IQVD------ 1429
Cdd:COG4913   401 EALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARL--LAL-RDALAEALGLDEAEL-PFVGelIEVRpeeerw 476

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1430 -GSV-----NLSHRLLSPSRRFS---------PSRSCGDYDNRSTSQCPDGPIDVDPD-LVRK----------GVRNLMH 1483
Cdd:COG4913   477 rGAIervlgGFALTLLVPPEHYAaalrwvnrlHLRGRLVYERVRTGLPDPERPRLDPDsLAGKldfkphpfraWLEAELG 556

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1484 Q---------VAQLER------------------EKDDYK-----SQLGA-AKKQLQDAADQQLRCDAKLGKLQAMLRNL 1530
Cdd:COG4913   557 RrfdyvcvdsPEELRRhpraitragqvkgngtrhEKDDRRrirsrYVLGFdNRAKLAALEAELAELEEELAEAEERLEAL 636

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1531 QEEKSNLETDRkmkiSAIQALEEKLKHRNDeCQMLRERLAQTEMQLAATSEENGQneerLEKSRQQCSKLDNEKRQLQEE 1610
Cdd:COG4913   637 EAELDALQERR----EALQRLAEYSWDEID-VASAEREIAELEAELERLDASSDD----LAALEEQLEELEAELEELEEE 707

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1611 LAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCSIRQ-MAERLENQNRALTQ----------LEDRCTALKSTVDQLKE 1679
Cdd:COG4913   708 LDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLeLRALLEERFAAALGdaverelrenLEERIDALRARLNRAEE 787


                  ....
gi 665394924 1680 RLQK 1683
Cdd:COG4913   788 ELER 791
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 521-1232 3.36e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 55.82  E-value: 3.36e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   521 KFQNTSETLRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLsELLQERESLQRGLDDIRVQKQQSEMGRADINSAFE 600
Cdd:TIGR00606  330 KLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSL-ATRLELDGFERGPFSERQIKNFHTLVIERQEDEAK 408

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   601 NLSSDYEKMQLNCGKLQKRIDSMEEDKKAVE--LEIQRILKDKNITELNLRSEEDRSSRLREETISLREElnrvSLNRDL 678
Cdd:TIGR00606  409 TAAQLCADLQSKERLKQEQADEIRDEKKGLGrtIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQ----ELRKAE 484

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   679 LEQQRIESDNLINLLEKQKSDLEYDLDKLLLEKCDLQEKHEKLsNNSCSTSDELKSVQNCLQEAQEERKKLRIQSVDQCN 758
Cdd:TIGR00606  485 RELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQL-NHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELT 563

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   759 EIGELKKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAMCRK------KEALNEELMR 832
Cdd:TIGR00606  564 SLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKlfdvcgSQDEESDLER 643

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   833 TRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLESVLFDTNTSLEATEERRSQLER 912
Cdd:TIGR00606  644 LKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEK 723

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   913 DLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLLNAARAAESdfNQKIANLQACAEEAAKrhgeeILQLRNALEKR 992
Cdd:TIGR00606  724 RRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEE--QETLLGTIMPEEESAK-----VCLTDVTIMER 796

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   993 MQQALQALQTAKDDEIEKLQE---RLATLQAHLESLVQQHEEALIRAESEKQQALLiahRDKQAVAERLEAVSRDLKTEQ 1069
Cdd:TIGR00606  797 FQMELKDVERKIAQQAAKLQGsdlDRTVQQVNQEKQEKQHELDTVVSKIELNRKLI---QDQQEQIQHLKSKTNELKSEK 873

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1070 ESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEhkikleecIRKQELQLSSLREERESLcrvseelkmeIRLKEDR 1149
Cdd:TIGR00606  874 LQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQ--------DSPLETFLEKDQQEKEEL----------ISSKETS 935

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1150 MESTNNELQDALRKSKEGEGFIDSLRKELTD-CRRQLADSNIERDKYSGSNKELRDHVKRVESAKREQARAIEEALQKIS 1228
Cdd:TIGR00606  936 NKKAQDKVNDIKEKVKNIHGYMKDIENKIQDgKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQER 1015


                   ....
gi 665394924  1229 NLED 1232
Cdd:TIGR00606 1016 WLQD 1019
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1113-1776 4.14e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.46  E-value: 4.14e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1113 ECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDRMESTNNElqdalrkskegEGFIDSLRKELTDCRRQLADSNIER 1192
Cdd:PRK03918  148 EKVVRQILGLDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENI-----------EELIKEKEKELEEVLREINEISSEL 216

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1193 DKYSGSNKELRDHVKRVESAKreqaraieealQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQlqka 1272
Cdd:PRK03918  217 PELREELEKLEKEVKELEELK-----------EEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEK---- 281

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1273 qVEFAQKDEGGKELQCKLVaevELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEhRFHAREQELAQRLEE 1352
Cdd:PRK03918  282 -VKELKELKEKAEEYIKLS---EFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLE-ELKKKLKELEKRLEE 356

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1353 GRGREKRLEDQKHNLEvcladatqQIQELKARLGGAEgrIRALDEQLSCVELHKRDTEQKLSSVVHTLRRIAGIQVDGSV 1432
Cdd:PRK03918  357 LEERHELYEEAKAKKE--------ELERLKKRLTGLT--PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKK 426

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1433 NLShRLLSPSRRfspsrscgdydnrstsqCPdgpidvdpdlvrkgvrnlmhqVAQLEREKDDYKSQLGAAKKQLQDAADQ 1512
Cdd:PRK03918  427 AIE-ELKKAKGK-----------------CP---------------------VCGRELTEEHRKELLEEYTAELKRIEKE 467

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1513 QLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKISA--IQALEEKLKHRN--------DECQMLRERLAQTEMQLAATSEE 1582
Cdd:PRK03918  468 LKEIEEKERKLRKELRELEKVLKKESELIKLKELAeqLKELEEKLKKYNleelekkaEEYEKLKEKLIKLKGEIKSLKKE 547

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1583 ngqnEERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQRVA-MEGDLTRLQMALQEKDcsirqmaeRLENQNRALT 1661
Cdd:PRK03918  548 ----LEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEeLEERLKELEPFYNEYL--------ELKDAEKELE 615

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1662 QLEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEQGHcSQANEDKLKLvQKSLQTAENEKRILTERLDSAQ 1741
Cdd:PRK03918  616 REEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEY-EELREEYLEL-SRELAGLRAELEELEKRREEIK 693

                         650       660       670
                  ....*....|....*....|....*....|....*
gi 665394924 1742 TNLNELRRsqqaQLDGNQRLQEQVTDLEVQRSALE 1776
Cdd:PRK03918  694 KTLEKLKE----ELEEREKAKKELEKLEKALERVE 724
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1290-1832 4.45e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 55.31  E-value: 4.45e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1290 LVAEVELKERAQQELCQIKKQLSDLE--ANLCATRQELGRARCQNNQEEHRFHA-----REQELAQRLEEGRGREKRLED 1362
Cdd:COG4913   230 LVEHFDDLERAHEALEDAREQIELLEpiRELAERYAAARERLAELEYLRAALRLwfaqrRLELLEAELEELRAELARLEA 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1363 QKHNLEVCLADATQQIQELKARLGGAEG-RIRALDEQLSCVELHKRDTEQKLSSVVHTLRRIagiqvdgsvnlshrllsp 1441
Cdd:COG4913   310 ELERLEARLDALREELDELEAQIRGNGGdRLEQLEREIERLERELEERERRRARLEALLAAL------------------ 371

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1442 srrfspsrscgdydnrstsqcpdgpiDVDPDLVRKGVRNLMHQVAQLereKDDYKSQLGAAKKQLQDAADQQLRCDAKLG 1521
Cdd:COG4913   372 --------------------------GLPLPASAEEFAALRAEAAAL---LEALEEELEALEEALAEAEAALRDLRRELR 422

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1522 KLQAMLRNLQEEKSNLetDRKMkISAIQALEEKLKHRNDECQMLRE----RLAQTEMQLAATSEENGQ------------ 1585
Cdd:COG4913   423 ELEAEIASLERRKSNI--PARL-LALRDALAEALGLDEAELPFVGElievRPEEERWRGAIERVLGGFaltllvppehya 499

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1586 ---------------NEERLEKSRQQCSKLDNEKRQLQEELAKVEGRAS---KLELQR------VAMEGDLTRLQMALQe 1641
Cdd:COG4913   500 aalrwvnrlhlrgrlVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRawlEAELGRrfdyvcVDSPEELRRHPRAIT- 578

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1642 KDCSIRQMAERLE-NQNRALTQL-------EDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEQGHCSQANE 1713
Cdd:COG4913   579 RAGQVKGNGTRHEkDDRRRIRSRyvlgfdnRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSW 658

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1714 DKLKL--VQKSLQTAENEK----------RILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQLRI 1781
Cdd:COG4913   659 DEIDVasAEREIAELEAELerldassddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEA 738

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|.
gi 665394924 1782 AKWNQESGGDKDLTNGNGGGNGEEELSRQLKSSQREKSELRSKLQTLQDKV 1832
Cdd:COG4913   739 AEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEEL 789
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1479-1836 4.78e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 55.03  E-value: 4.78e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1479 RNLMHQVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAML---RNLQEEKSNLETDRKmkisaiqALEEKL 1555
Cdd:TIGR04523  162 NDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIqknKSLESQISELKKQNN-------QLKDNI 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1556 KHRNDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQRVamEGDLTRL 1635
Cdd:TIGR04523  235 EKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKE--QDWNKEL 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1636 QMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEQGHCSQANEDK 1715
Cdd:TIGR04523  313 KSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQ 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1716 LKLVQKSLQTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQ---LRIAKWNQESGGDK 1792
Cdd:TIGR04523  393 INDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIiknLDNTRESLETQLKV 472

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 665394924  1793 DLTNGNGGGNGEEELSRQLKSSQREKSELRSKLQTLQDKVKQLE 1836
Cdd:TIGR04523  473 LSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLT 516
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 356-856 1.06e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.97  E-value: 1.06e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   356 KQSQRSNDELQNQLATLKVQYESARHEIMERdQRLLElmNQLKKLEDRCAQAESQAALASRYSDEIERLNNSMREIAQAV 435
Cdd:pfam15921  306 EQARNQNSMYMRQLSDLESTVSQLRSELREA-KRMYE--DKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKL 382

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   436 VQDAENADREADAEV----------TGGVMQHMHLTRDAASVVGGAGGAGSTAGGGgKSPRRNSTRASQAFAEGTISAVQ 505
Cdd:pfam15921  383 LADLHKREKELSLEKeqnkrlwdrdTGNSITIDHLRRELDDRNMEVQRLEALLKAM-KSECQGQMERQMAAIQGKNESLE 461

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   506 AaLHKYQLALHDMQVKFQNTSETLRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSEL-------LQERESLQRGL 578
Cdd:pfam15921  462 K-VSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLrsrvdlkLQELQHLKNEG 540

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   579 DDIRVQKQQSEMGR---ADINSAFENLSSDYEKMQLNCGKLQKRIDSMEEDKKAVELEIQ---------RILKDKNitEL 646
Cdd:pfam15921  541 DHLRNVQTECEALKlqmAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINdrrlelqefKILKDKK--DA 618

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   647 NLRSEEDRSSRLREETISLreeLNRVSLNRDLLEQQRIESDNLINLLEKQKSDLEYDLDKLLLEKCDLQEKHEKLSNNSC 726
Cdd:pfam15921  619 KIRELEARVSDLELEKVKL---VNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTN 695

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   727 STSDELKSVQNCLQEAQEERKKLRIQ-------SVDQCNEIGELKKELAILDKARLELETDNLSAGEKLKCLQLEKEKIL 799
Cdd:pfam15921  696 KLKMQLKSAQSELEQTRNTLKSMEGSdghamkvAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLS 775

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 665394924   800 QDLACVTRDRGDIHNQLTAMCRKKEALNEELMRTRQRLE----QTTETNSRLNRNLEEMVK 856
Cdd:pfam15921  776 QELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDkaslQFAECQDIIQRQEQESVR 836
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 500-917 1.12e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.87  E-value: 1.12e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   500 TISAVQAALHKYQLALHDMQVKFQNTSETLRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSELLQERE------- 572
Cdd:TIGR04523  233 NIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEqdwnkel 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   573 -----SLQRGLDDIRVQKQQSEMGRADINSAFE-------NLSSDYEKMQLNCGKLQKRIDSMEEDKKAVELEIQRILKD 640
Cdd:TIGR04523  313 kselkNQEKKLEEIQNQISQNNKIISQLNEQISqlkkeltNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQ 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   641 KNITELNLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQRIESDNLINLLEKQKSDLEYDLDKLLLEKCDLQEKHEK 720
Cdd:TIGR04523  393 INDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKV 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   721 LSNNSCSTSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQ 800
Cdd:TIGR04523  473 LSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDF 552

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   801 DLacvtrdrgdihnqltamcrKKEALNEELMRTRQRLEQTTETNSRL---NRNLEEMVKDVEEKQVV----IDLHEKDTH 873
Cdd:TIGR04523  553 EL-------------------KKENLEKEIDEKNKEIEELKQTQKSLkkkQEEKQELIDQKEKEKKDlikeIEEKEKKIS 613

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....
gi 665394924   874 RLNELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEA 917
Cdd:TIGR04523  614 SLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEI 657
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
985-1417 1.52e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 53.23  E-value: 1.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  985 LRNALEKRMQQALQALQTAK-------DDEIEKLQERLATLQAHLESLVQ-QHEEALIRAESEKQQALLIAHRDKQAVAE 1056
Cdd:COG4717    43 IRAMLLERLEKEADELFKPQgrkpelnLKELKELEEELKEAEEKEEEYAElQEELEELEEELEELEAELEELREELEKLE 122

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1057 RLEAVSRDLKtEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECIRKQELQLSSLREERESLCRVS 1136
Cdd:COG4717   123 KLLQLLPLYQ-ELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEEL 201

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1137 EELKMEIRLKEDRMESTNNELQDALRKSK--EGEGFIDSLRKELTDCRRQLA---------------DSNIERDK----- 1194
Cdd:COG4717   202 EELQQRLAELEEELEEAQEELEELEEELEqlENELEAAALEERLKEARLLLLiaaallallglggslLSLILTIAgvlfl 281

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1195 --------YSGSNKELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQdLNATK 1266
Cdd:COG4717   282 vlgllallFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLRE-AEELE 360

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1267 AQLQKAQVEfAQKDEGGKELQCKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEE-----HRFHA 1341
Cdd:COG4717   361 EELQLEELE-QEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEEleeelEELEE 439

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 665394924 1342 REQELAQRLEEGRGREKRLEDQKHNLE--VCLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTEQKLSSVV 1417
Cdd:COG4717   440 ELEELEEELEELREELAELEAELEQLEedGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERLPPV 517
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 546-1275 1.99e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 53.52  E-value: 1.99e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   546 LTTKMQQLTE-----KLDSSNSKLSELLQERESLQRGL-----DDIRVQKQQSEMGRADINSAFENLSSDYEKMQLNC-G 614
Cdd:TIGR01612  972 LIDKINELDKafkdaSLNDYEAKNNELIKYFNDLKANLgknkeNMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIhT 1051

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   615 KLQKRIDSME-EDKKAVELEIQRILKDKNITELNLRSEEDR------SSRLREETISLREELNRV-----SLNRDL---- 678
Cdd:TIGR01612 1052 SIYNIIDEIEkEIGKNIELLNKEILEEAEINITNFNEIKEKlkhynfDDFGKEENIKYADEINKIkddikNLDQKIdhhi 1131

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   679 --LEQQRIESDNLINLLEKQKSDLEYDLDKLLLEkcDLQEKHEKLSNNSCSTSDELKSVqnclqeaQEERKKLriqsvdq 756
Cdd:TIGR01612 1132 kaLEEIKKKSENYIDEIKAQINDLEDVADKAISN--DDPEEIEKKIENIVTKIDKKKNI-------YDEIKKL------- 1195

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   757 CNEIGELKKelailDKARLE-LETDNLSAGEKLKCLQLEK---------------EKILQDLACVTRDRGDIHNQLTAMC 820
Cdd:TIGR01612 1196 LNEIAEIEK-----DKTSLEeVKGINLSYGKNLGKLFLEKideekkksehmikamEAYIEDLDEIKEKSPEIENEMGIEM 1270

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   821 RKKEAL--------------------NEELMRTRQRLEQTTETNSR------LNRNLEEMVKDVEEKQVVIDLHEKDTHR 874
Cdd:TIGR01612 1271 DIKAEMetfnishdddkdhhiiskkhDENISDIREKSLKIIEDFSEesdindIKKELQKNLLDAQKHNSDINLYLNEIAN 1350

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   875 LNELLaALRSEKESLESVLFDTNTSLEATEERRSQLERD--LQEALVREESLKNHVARLQ-----KELEQCQRKAQETKT 947
Cdd:TIGR01612 1351 IYNIL-KLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSekLIKKIKDDINLEECKSKIEstlddKDIDECIKKIKELKN 1429

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   948 QLLnaarAAESDFNQKIANlqacaeeaAKRHGEEILQLRNALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQ 1027
Cdd:TIGR01612 1430 HIL----SEESNIDTYFKN--------ADENNENVLLLFKNIEMADNKSQHILKIKKDNATNDHDFNINELKEHIDKSKG 1497

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1028 QHEEALIRAESEKQQALLIAHRdKQAVAERLEAVSR-DLKTEqesLDRSRREANA-----RDEKQRAAIAQLKDEMVQMR 1101
Cdd:TIGR01612 1498 CKDEADKNAKAIEKNKELFEQY-KKDVTELLNKYSAlAIKNK---FAKTKKDSEIiikeiKDAHKKFILEAEKSEQKIKE 1573

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1102 TKEEEHKIKLE------------------ECIRKQELQLSSLREERESLCRVSEELkmEIRLKEDRMESTNNELQDALRK 1163
Cdd:TIGR01612 1574 IKKEKFRIEDDaakndksnkaaidiqlslENFENKFLKISDIKKKINDCLKETESI--EKKISSFSIDSQDTELKENGDN 1651

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1164 SKEGEGFIDSLRkeltDCRRQLADSNIERDKYsgsNKELRDHVKRVESAKREQARAIEEALQKISnlEDTKNSLENERTR 1243
Cdd:TIGR01612 1652 LNSLQEFLESLK----DQKKNIEDKKKELDEL---DSEIEKIEIDVDQHKKNYEIGIIEKIKEIA--IANKEEIESIKEL 1722

                          810       820       830
                   ....*....|....*....|....*....|....
gi 665394924  1244 LSTILKETENHFtkTTQDLNA--TKAQLQKAQVE 1275
Cdd:TIGR01612 1723 IEPTIENLISSF--NTNDLEGidPNEKLEEYNTE 1754
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 343-937 2.60e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.63  E-value: 2.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  343 AVQQAKRAADDELKQSQRSNDELQNQLATLKVQYESARHEIMERDQRLLELMNQLKKLEDRCAQAESQAALasrysdEIE 422
Cdd:COG1196   236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIAR------LEE 309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  423 RLNNSMREIAQAVVQDAENADREADAEVtggvmqhmhltrdaasvvggaggagstaggggkspRRNSTRASQAFAEGTIS 502
Cdd:COG1196   310 RRRELEERLEELEEELAELEEELEELEE-----------------------------------ELEELEEELEEAEEELE 354

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  503 AVQAALHKYQLALHDMQVKFQNTSETLRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSELLQERESLQRGLDDIR 582
Cdd:COG1196   355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE 434

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  583 VQKQQSEMGRADINSAFENLSSDYEKMQLNCGKLQKRIDSMEEDKKAVELEIQRILKDKNITELNLRSEEDRSSRLREET 662
Cdd:COG1196   435 EEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAAL 514

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  663 ISLREELNRVSLNRDLLEQQRIESDNLINLLEKQKSDLEYDLDKllLEKCDLQEKHEKLSNNSCSTSDELKsvqnclQEA 742
Cdd:COG1196   515 LLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEV--AAAAIEYLKAAKAGRATFLPLDKIR------ARA 586

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  743 QEERKKLRIQSVDQCNEIGELKKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAMCRK 822
Cdd:COG1196   587 ALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGS 666

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  823 KEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLESVLFDTntsLEA 902
Cdd:COG1196   667 RRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE---LLE 743

                         570       580       590
                  ....*....|....*....|....*....|....*
gi 665394924  903 TEERRSQLERDLQEALVREESLKNHVARLQKELEQ 937
Cdd:COG1196   744 EEELLEEEALEELPEPPDLEELERELERLEREIEA 778
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 548-1157 2.63e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.72  E-value: 2.63e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   548 TKMQQLTEKLDSSNSKLSELLQERESLQRGLDDIRVQKQQSEMGRADINSAFENLSSDYEKMQLNCGKLQKRIDSMEEDK 627
Cdd:TIGR04523   96 DKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENEL 175

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   628 KAVELEIQRILKD----------KNITELNLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQRIESDNLINLLEKQK 697
Cdd:TIGR04523  176 NLLEKEKLNIQKNidkiknkllkLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQL 255

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   698 SDLEYDLDKlllEKCDLQEKHEKLSNNscstSDELKSVQNCLQEAQEERKKLRIQSvdQCNEIGELKKELAILDKARLEL 777
Cdd:TIGR04523  256 NQLKDEQNK---IKKQLSEKQKELEQN----NKKIKELEKQLNQLKSEISDLNNQK--EQDWNKELKSELKNQEKKLEEI 326

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   778 ETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKD 857
Cdd:TIGR04523  327 QNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKL 406

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   858 VEEKQVVI-------DLHEKDTHRLNELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVAR 930
Cdd:TIGR04523  407 NQQKDEQIkklqqekELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQ 486

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   931 LQKELEQcqrkaqetKTQLLNAARAAESDFNQKIANLqacaeeaaKRHGEEILQLRNALEKRMQQALQALQTaKDDEIEK 1010
Cdd:TIGR04523  487 KQKELKS--------KEKELKKLNEEKKELEEKVKDL--------TKKISSLKEKIEKLESEKKEKESKISD-LEDELNK 549

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1011 LQERLATLQahLESLVQQHEEALIRAESEkQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSrreanardekqraaI 1090
Cdd:TIGR04523  550 DDFELKKEN--LEKEIDEKNKEIEELKQT-QKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKK--------------I 612

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 665394924  1091 AQLKDEmvqMRTKEEEHKiKLEECIRKQELQLSSLREERESlcrVSEELKmEIRLKEDRMESTNNEL 1157
Cdd:TIGR04523  613 SSLEKE---LEKAKKENE-KLSSIIKNIKSKKNKLKQEVKQ---IKETIK-EIRNKWPEIIKKIKES 671
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 900-1833 3.36e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 52.48  E-value: 3.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   900 LEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQR---KAQETKTQLLNAARAAESDFNQKIANLQACAEEAAK 976
Cdd:pfam01576   14 LQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETElcaEAEEMRARLAARKQELEEILHELESRLEEEEERSQQ 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   977 RHGEEilqlrnaleKRMQQALQALQTAKDDEiEKLQERLATLQAHLESLVQQHEEALIRAESEKQQAlliaHRDKQAVAE 1056
Cdd:pfam01576   94 LQNEK---------KKMQQHIQDLEEQLDEE-EAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKL----SKERKLLEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1057 RLEAVSRDLKTEQESLDRSRREANardeKQRAAIAQLKDEMvqmrTKEEEHKIKLEECIRKQELQLSSLREERESLCRVS 1136
Cdd:pfam01576  160 RISEFTSNLAEEEEKAKSLSKLKN----KHEAMISDLEERL----KKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQI 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1137 EELKMEIRLKEDrmestnnELQDALRKSKEGEGFIDSLRKELTDCRRQLA----DSNIERDKYSGSNKELRDHVKRVESA 1212
Cdd:pfam01576  232 AELRAQLAKKEE-------ELQAALARLEEETAQKNNALKKIRELEAQISelqeDLESERAARNKAEKQRRDLGEELEAL 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1213 KRE-------QARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKE 1285
Cdd:pfam01576  305 KTEledtldtTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALES 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1286 LQCKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEHRFHAREQELAQRLEEGRGREKRLEDQKH 1365
Cdd:pfam01576  385 ENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVS 464

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1366 NLEVCLADATQQIQE-------LKARLGGAEGRIRALDEQLSCVELHKRDTEQKLSSVvhtlrriaGIQVDGSVNLSHRL 1438
Cdd:pfam01576  465 SLESQLQDTQELLQEetrqklnLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTL--------QAQLSDMKKKLEED 536

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1439 LSPSRRFSPSRSCGDYDNRSTSQCPDGPIDVDPDLVRKGVRnlmhqvaqLEREKDDYKSQLGAAKKQLQDAADQQLRCDA 1518
Cdd:pfam01576  537 AGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNR--------LQQELDDLLVDLDHQRQLVSNLEKKQKKFDQ 608

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1519 KLGKLQAMLRNLQEEKSNLETDRKMK----ISAIQALEEKLKHRNDECQMLRERLAQTEmQLAATSEENGQNEERLEKSR 1594
Cdd:pfam01576  609 MLAEEKAISARYAEERDRAEAEAREKetraLSLARALEEALEAKEELERTNKQLRAEME-DLVSSKDDVGKNVHELERSK 687

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1595 ----QQCSKLDNEKRQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKD--------CSIRQMAERLENQNRALTQ 1662
Cdd:pfam01576  688 raleQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERDLQARDEQGeekrrqlvKQVRELEAELEDERKQRAQ 767

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1663 -------LEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEQG-------HCSQANEDKLKLVQKSLQTAEN 1728
Cdd:pfam01576  768 avaakkkLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARasrdeilAQSKESEKKLKNLEAELLQLQE 847

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1729 EKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQLRIAKWNQESGGDKDLTNGNGGGNGEEELS 1808
Cdd:pfam01576  848 DLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELA 927

                          970       980       990
                   ....*....|....*....|....*....|....*
gi 665394924  1809 RQLKSSQ----------REKSELRSKLQTLQDKVK 1833
Cdd:pfam01576  928 AERSTSQksesarqqleRQNKELKAKLQEMEGTVK 962
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 347-1065 4.08e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 52.38  E-value: 4.08e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   347 AKRAADDELKQSQRSNDELQNQLATLKVQYESARHEIMERDQRLLELMNQLKKLEDRcAQAESQAALASrYSDEIERLNN 426
Cdd:TIGR02169  231 EKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE-EQLRVKEKIGE-LEAEIASLER 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   427 SMREIAQAVvQDAENADREADAEVTGGVMQHMHLTRDAASVVGGAGGAGSTAGGGGKspRRNSTRASqafaegtISAVQA 506
Cdd:TIGR02169  309 SIAEKEREL-EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE--ELEDLRAE-------LEEVDK 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   507 ALHKYQLALHDMQVKFQNTSETLRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSELLQERESLQRGLDDIRVQKQ 586
Cdd:TIGR02169  379 EFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLE 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   587 QSEMGRADINSAFENLSSDYEKMQLNCGKLQKRIDSMEEDKKAVELEI-----QRILKDKNI-----TELNLRSEEDRSS 656
Cdd:TIGR02169  459 QLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVrggraVEEVLKASIqgvhgTVAQLGSVGERYA 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   657 RLREETISLReeLNRVSLNRDLLEQQRIESDNLINL-------LEKQKsDLEYDLDKLLLEKC-----DLQEKHEKLSNN 724
Cdd:TIGR02169  539 TAIEVAAGNR--LNNVVVEDDAVAKEAIELLKRRKAgratflpLNKMR-DERRDLSILSEDGVigfavDLVEFDPKYEPA 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   725 SCSTSDELKSVQNcLQEAQEERKKLRIQSVDqcNEI---------GELKKELAILDKARLELETDNLSagEKLKCLQLEK 795
Cdd:TIGR02169  616 FKYVFGDTLVVED-IEAARRLMGKYRMVTLE--GELfeksgamtgGSRAPRGGILFSRSEPAELQRLR--ERLEGLKREL 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   796 EKILQDLACVTRDRgdihNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKqvvidlhekdthrl 875
Cdd:TIGR02169  691 SSLQSELRRIENRL----DELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQE-------------- 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   876 nelLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVRE-----ESLKNHVARLQKEL-------------EQ 937
Cdd:TIGR02169  753 ---IENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEiqaelSKLEEEVSRIEARLreieqklnrltleKE 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   938 CQRKAQETKTQLLNAARAAESDFNQKIANLQACAEE---AAKRHGEEILQLRNALE------KRMQQALQALQTAKDD-- 1006
Cdd:TIGR02169  830 YLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEEleeELEELEAALRDLESRLGdlkkerDELEAQLRELERKIEEle 909

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 665394924  1007 -EIEKLQERLATLQAHLESLVQQ--HEEALIRAESEKQQALLIAhRDKQAVAERLEAVSRDL 1065
Cdd:TIGR02169  910 aQIEKKRKRLSELKAKLEALEEElsEIEDPKGEDEEIPEEELSL-EDVQAELQRVEEEIRAL 970
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 521-1380 4.59e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 51.97  E-value: 4.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   521 KFQNTSETLR----TTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSELLQERE---SLQRGLDDIRVQKQQSEMGRA 593
Cdd:TIGR00606  183 RYIKALETLRqvrqTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREivkSYENELDPLKNRLKEIEHNLS 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   594 DINSaFENLSSDYEKMQLNCGKLQKRIDSM--------EEDKKAVELEIQRILKDKNITELNLRSEEDRSSR----LREE 661
Cdd:TIGR00606  263 KIMK-LDNEIKALKSRKKQMEKDNSELELKmekvfqgtDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKerrlLNQE 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   662 TISLREELNRVSLNRDLLEQQRIESDNLINLLEKQ--------KSDLEYDLDKLLLEKCDLQEKHEKLSNNSCST-SDEL 732
Cdd:TIGR00606  342 KTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRleldgferGPFSERQIKNFHTLVIERQEDEAKTAAQLCADlQSKE 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   733 KSVQNCLQEAQEERKKL----RIQSVDQCNEIGELK-------------KELAILDKARLELETDnLSAGEK---LKCLQ 792
Cdd:TIGR00606  422 RLKQEQADEIRDEKKGLgrtiELKKEILEKKQEELKfvikelqqlegssDRILELDQELRKAERE-LSKAEKnslTETLK 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   793 LEKEKILQDLACVTRDRGDIHNQLTAMCRKKEALNEELMRTRQRL---EQTTETNSRLNRNLEEMVKDVEEKQVVID-LH 868
Cdd:TIGR00606  501 KEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMdkdEQIRKIKSRHSDELTSLLGYFPNKKQLEDwLH 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   869 E--KDTHRLNELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEAlVREESLKNHVARLQKELEqcqrKAQETK 946
Cdd:TIGR00606  581 SksKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDV-CGSQDEESDLERLKEEIE----KSSKQR 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   947 TQLLNAARAAESDFNQKIANLQACAeeaakrhgeEILQLRNALEKRMQQALQALQTAKDDEIEKLQErlatLQAHLESLV 1026
Cdd:TIGR00606  656 AMLAGATAVYSQFITQLTDENQSCC---------PVCQRVFQTEAELQEFISDLQSKLRLAPDKLKS----TESELKKKE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1027 QQHEEALIRAESEKQQALLIAHRDKQaVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEe 1106
Cdd:TIGR00606  723 KRRDEMLGLAPGRQSIIDLKEKEIPE-LRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQME- 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1107 hkikLEECIRKQELQLSSLreERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLR---KELTDCRR 1183
Cdd:TIGR00606  801 ----LKDVERKIAQQAAKL--QGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKsktNELKSEKL 874

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1184 QLADSNIERDKYSGSNKELRDHVKrvesakrEQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLN 1263
Cdd:TIGR00606  875 QIGTNLQRRQQFEEQLVELSTEVQ-------SLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIK 947

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1264 ATKAQLQKAQVEFAQKDEGGKELQcklvaevelKERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEHRFHARE 1343
Cdd:TIGR00606  948 EKVKNIHGYMKDIENKIQDGKDDY---------LKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQ 1018

                          890       900       910
                   ....*....|....*....|....*....|....*..
gi 665394924  1344 QELAQRLEEGRGREKRLEDQKHNLEVCLADATQQIQE 1380
Cdd:TIGR00606 1019 DNLTLRKRENELKEVEEELKQHLKEMGQMQVLQMKQE 1055
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1099-2009 8.49e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 51.20  E-value: 8.49e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1099 QMRTKEEEHKIKLEECIRKQELQLSSLREERESLCRVSEELKMeiRLKE-DRMESTNNELQDALRKSKEGEGFIDSLRKE 1177
Cdd:TIGR00606  210 KYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKN--RLKEiEHNLSKIMKLDNEIKALKSRKKQMEKDNSE 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1178 LTDCRRQLadsnierdkYSGSNKELRD----HVKRVESAKREQA---RAIEEALQKISNLEDTKNSLENERTRLSTILKE 1250
Cdd:TIGR00606  288 LELKMEKV---------FQGTDEQLNDlyhnHQRTVREKERELVdcqRELEKLNKERRLLNQEKTELLVEQGRLQLQADR 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1251 TENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKELQCKLVaevelKERAQQELCQIKKQLSDLEANLCATRQELGRARC 1330
Cdd:TIGR00606  359 HQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLV-----IERQEDEAKTAAQLCADLQSKERLKQEQADEIRD 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1331 QNNQEEHRFHAREQELAQRLEEGRGREKRLEDqkhnlevcLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKRdtE 1410
Cdd:TIGR00606  434 EKKGLGRTIELKKEILEKKQEELKFVIKELQQ--------LEGSSDRILELDQELRKAERELSKAEKNSLTETLKKE--V 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1411 QKLSSVVHTLRRIAGIQVDGSVNLSHRLLSPSRRFSPSRSCGD-----YDNRS------TSQCPDGP-----------ID 1468
Cdd:TIGR00606  504 KSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDkdeqiRKIKSrhsdelTSLLGYFPnkkqledwlhsKS 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1469 VDPDLVRKGVRNLMHQVAQLEREKDDYKSQLGAAKKQLQDAADQQLR-CDAKlgKLQAMLRNLQEEKSNLETDRKM---K 1544
Cdd:TIGR00606  584 KEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDvCGSQ--DEESDLERLKEEIEKSSKQRAMlagA 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1545 ISAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSeengqneerleksrqqcSKLDNEKRQLQEELAKVEGRASKLELQ 1624
Cdd:TIGR00606  662 TAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFI-----------------SDLQSKLRLAPDKLKSTESELKKKEKR 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1625 RVAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQLrGEIKTLQKELS- 1703
Cdd:TIGR00606  725 RDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDV-TIMERFQMELKd 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1704 -EQGHCSQANEDKLKLVQKSLQTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQLRIA 1782
Cdd:TIGR00606  804 vERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRR 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1783 KWNQESGGDKD------LTNGNGGGNGEEELSRQLKSSQREKSELRS-----------KLQTLQDKVKQLECDRKS---K 1842
Cdd:TIGR00606  884 QQFEEQLVELStevqslIREIKDAKEQDSPLETFLEKDQQEKEELISsketsnkkaqdKVNDIKEKVKNIHGYMKDienK 963

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1843 FSGGNAYDRAEKSNSFYGGAAESGEFDSNRYDVGGGNAGGGSfncGLDHSVIEQETRDLRLKVRRLETLLAEKESELARC 1922
Cdd:TIGR00606  964 IQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQ---DIDTQKIQERWLQDNLTLRKRENELKEVEEELKQH 1040

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1923 KARMN-----DSAKCHDGLDGDRYRSAQMHAEKLldAREQSHRQQVLRLENQISMLREQLAQEAKRRQQYILRSSK-ANR 1996
Cdd:TIGR00606 1041 LKEMGqmqvlQMKQEHQKLEENIDLIKRNHVLAL--GRQKGYEKEIKHFKKELREPQFRDAEEKYREMMIVMRTTElVNK 1118

                          970
                   ....*....|...
gi 665394924  1997 EMQHLRSTLGDSL 2009
Cdd:TIGR00606 1119 DLDIYYKTLDQAI 1131
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
986-1399 9.08e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.81  E-value: 9.08e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  986 RNALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEEAliRAESEKQQALLIAHRDKQAVAERLEAVSRDL 1065
Cdd:PRK02224  186 RGSLDQLKAQIEEKEEKDLHERLNGLESELAELDEEIERYEEQREQA--RETRDEADEVLEEHEERREELETLEAEIEDL 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1066 KTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECirkqELQLSSLREERESLCRVSEELKMEIRL 1145
Cdd:PRK02224  264 RETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAV----EARREELEDRDEELRDRLEECRVAAQA 339

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1146 KEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSnieRDKYSGSNKELRDHVKRVESAkreqARAIEEALQ 1225
Cdd:PRK02224  340 HNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDR---REEIEELEEEIEELRERFGDA----PVDLGNAED 412

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1226 KISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEfaqkdegGKELQCKLVAEVELKERAQQELC 1305
Cdd:PRK02224  413 FLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVE-------GSPHVETIEEDRERVEELEAELE 485

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1306 QIKKQLSDLEANL--------CATRQELGRARCQNNQE---EHRFHAREQELaqRLEEGRGREKRLEDQKHNLEVCLADA 1374
Cdd:PRK02224  486 DLEEEVEEVEERLeraedlveAEDRIERLEERREDLEEliaERRETIEEKRE--RAEELRERAAELEAEAEEKREAAAEA 563

                         410       420
                  ....*....|....*....|....*
gi 665394924 1375 TQQIQELKARLGGAEGRIRALDEQL 1399
Cdd:PRK02224  564 EEEAEEAREEVAELNSKLAELKERI 588
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1475-1836 9.39e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 50.81  E-value: 9.39e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1475 RKGVRNLMHQVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEEK 1554
Cdd:PRK02224  348 REDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRER 427

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1555 LKHRNDECQMLRERLAQTEMQLAA-TSEENGQNEE------RLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLElQRVA 1627
Cdd:PRK02224  428 EAELEATLRTARERVEEAEALLEAgKCPECGQPVEgsphveTIEEDRERVEELEAELEDLEEEVEEVEERLERAE-DLVE 506

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1628 MEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEqgh 1707
Cdd:PRK02224  507 AEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAE--- 583

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1708 CSQANEDKLKLVQKSLQTAENEKRI--LTERLDsAQTNLNELRRSQQAQLdgNQRLQEQVTDLEVQR-SALESQLRIAKW 1784
Cdd:PRK02224  584 LKERIESLERIRTLLAAIADAEDEIerLREKRE-ALAELNDERRERLAEK--RERKRELEAEFDEARiEEAREDKERAEE 660

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 665394924 1785 NQESGGDKdLTNGNGGGNGEEELSRQLKSSQREKSELRSKLQTLQDKVKQLE 1836
Cdd:PRK02224  661 YLEQVEEK-LDELREERDDLQAEIGAVENELEELEELRERREALENRVEALE 711
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1484-1685 9.69e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.15  E-value: 9.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1484 QVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEEKLKHRNDECQ 1563
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1564 MLRERLA-----------QTEMQLAATSEENGQNEERL-------EKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQR 1625
Cdd:COG4942   101 AQKEELAellralyrlgrQPPLALLLSPEDFLDAVRRLqylkylaPARREQAEELRADLAELAALRAELEAERAELEALL 180

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1626 VAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSA 1685
Cdd:COG4942   181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1248-1684 1.76e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.77  E-value: 1.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1248 LKETENHFTKTTQDLNATKAQLQKAQVEF--AQKDEGGKELQCKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQEL 1325
Cdd:COG4717    83 AEEKEEEYAELQEELEELEEELEELEAELeeLREELEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELRELE 162

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1326 GRARCQNNQEEHRFHAREQELAQRLEEGRGREKRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDEQLSCVELH 1405
Cdd:COG4717   163 EELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALE 242

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1406 KRDTEQKLSSVVHTLrrIAGIQVDGSVNLSHRLLSPSRRFSPSRSCGDYDNRSTSQCPDGPIDVDPDLVRKGVRNLMHQv 1485
Cdd:COG4717   243 ERLKEARLLLLIAAA--LLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEE- 319

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1486 aQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEE--KLKHRNDECQ 1563
Cdd:COG4717   320 -ELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEElrAALEQAEEYQ 398

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1564 MLRERLAQTEMQLAATSEENGQN---------EERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQRVAMEgdltr 1634
Cdd:COG4717   399 ELKEELEELEEQLEELLGELEELlealdeeelEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELAE----- 473

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 665394924 1635 lqmalqekdcsIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKS 1684
Cdd:COG4717   474 -----------LLQELEELKAELRELAEEWAALKLALELLEEAREEYREE 512
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 869-1692 1.81e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 50.34  E-value: 1.81e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  869 EKDTH--RLNELLAALRSEKESL---ESVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVaRLQKELEQCQRKAQ 943
Cdd:COG3096   279 ERRELseRALELRRELFGARRQLaeeQYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTAL-RQQEKIERYQEDLE 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  944 EtktqlLNAARAAESDFNQKIANLQACAEEAAKRHGEEILQLRNALEKRMQ-------------QALQALQTAK------ 1004
Cdd:COG3096   358 E-----LTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQaldvqqtraiqyqQAVQALEKARalcglp 432

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1005 DDEIEKLQERLATLQAHLESL-----------------VQQHEEAL-----IRAESEKQQA------LLIAHRDKQAVAE 1056
Cdd:COG3096   433 DLTPENAEDYLAAFRAKEQQAteevleleqklsvadaaRRQFEKAYelvckIAGEVERSQAwqtareLLRRYRSQQALAQ 512

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1057 RLEAVSRDLKtEQESLDRSRREAnardEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECIRKQELQLSSLREERESLCRVS 1136
Cdd:COG3096   513 RLQQLRAQLA-ELEQRLRQQQNA----ERLLEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQL 587

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1137 EELKMEIRLKEDRmESTNNELQDALRKSKE--GEGFIDSlrKELTDCRRQLADSnierdkysgsnkelrdhvKRVESAKR 1214
Cdd:COG3096   588 EQLRARIKELAAR-APAWLAAQDALERLREqsGEALADS--QEVTAAMQQLLER------------------EREATVER 646

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1215 EQARAIEEALQK-ISNLEDTKNSlenERTRLSTIlketenhftkttqdlnatkaqlqkaqvefaqKDEGGKELQCKLVAE 1293
Cdd:COG3096   647 DELAARKQALESqIERLSQPGGA---EDPRLLAL-------------------------------AERLGGVLLSEIYDD 692

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1294 VELKERAQ--------------QELCQIKKQLSDLE------------ANLCATR----QELGRARC-QNNQEEHRFH-- 1340
Cdd:COG3096   693 VTLEDAPYfsalygparhaivvPDLSAVKEQLAGLEdcpedlyliegdPDSFDDSvfdaEELEDAVVvKLSDRQWRYSrf 772

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1341 ---------AREQ----------ELAQRLEEGRGREKRLEDQKHNLEVCLA---------DATQQIQELKARLGGAEGRI 1392
Cdd:COG3096   773 pevplfgraAREKrleelraerdELAEQYAKASFDVQKLQRLHQAFSQFVGghlavafapDPEAELAALRQRRSELEREL 852

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1393 RALDEQlscvelhkrdtEQKLssvvhtlrRIAGIQVDGSVNLSHRLLspsrrfspsrscgdydnrstsqcPDGPIDVDPD 1472
Cdd:COG3096   853 AQHRAQ-----------EQQL--------RQQLDQLKEQLQLLNKLL-----------------------PQANLLADET 890

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1473 LvrkgvrnlMHQVAQLEREKDdyksqlgaakkQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETdRKMKISAIQALE 1552
Cdd:COG3096   891 L--------ADRLEELREELD-----------AAQEAQAFIQQHGKALAQLEPLVAVLQSDPEQFEQ-LQADYLQAKEQQ 950

                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1553 EKLKHRNDECQMLRERL-----AQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEEL---------------A 1612
Cdd:COG3096   951 RRLKQQIFALSEVVQRRphfsyEDAVGLLGENSDLNEKLRARLEQAEEARREAREQLRQAQAQYsqynqvlaslkssrdA 1030

                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1613 KVEG-RASKLELQRVAMEGDLTRLQMALQEKDcsirQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQL 1691
Cdd:COG3096  1031 KQQTlQELEQELEELGVQADAEAEERARIRRD----ELHEELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQE 1106


                  .
gi 665394924 1692 R 1692
Cdd:COG3096  1107 R 1107
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
834-1082 1.95e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 49.63  E-value: 1.95e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  834 RQRLEQTTETNSRLNRNLEEMVKDVEEKqvvidlhekdthrLNELLAALRSEKEslESVLFDTNTSLEATEERRSQLERD 913
Cdd:COG3206   163 EQNLELRREEARKALEFLEEQLPELRKE-------------LEEAEAALEEFRQ--KNGLVDLSEEAKLLLQQLSELESQ 227

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  914 LQEALVREESLKNHVARLQKELEQCQRKAQETKT-QLLNAARAAESDFNQKIANLQAcaeeaakRHGE------EILQLR 986
Cdd:COG3206   228 LAEARAELAEAEARLAALRAQLGSGPDALPELLQsPVIQQLRAQLAELEAELAELSA-------RYTPnhpdviALRAQI 300

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  987 NALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQQheealIRAESEKQQALLIAHRDKQAVAERLEAVSRdlK 1066
Cdd:COG3206   301 AALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEAR-----LAELPELEAELRRLEREVEVARELYESLLQ--R 373

                         250
                  ....*....|....*.
gi 665394924 1067 TEQESLDRSRREANAR 1082
Cdd:COG3206   374 LEEARLAEALTVGNVR 389
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1476-1836 1.98e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 49.63  E-value: 1.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1476 KGVRNLMHQVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEEKL 1555
Cdd:TIGR04523  321 KKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKI 400

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1556 KHRNDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQRVAMEGDLTRL 1635
Cdd:TIGR04523  401 QNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKI 480

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1636 QMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELseqghcsqaNEDK 1715
Cdd:TIGR04523  481 KQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDEL---------NKDD 551

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1716 lklvqkslqtAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQLriakwnqesggdkdlt 1795
Cdd:TIGR04523  552 ----------FELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEI---------------- 605

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 665394924  1796 ngNGGGNGEEELSRQLKSSQREKSELRSKLQTLQDKVKQLE 1836
Cdd:TIGR04523  606 --EEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLK 644
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 721-957 2.16e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  721 LSNNSCSTSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDKARLELEtdnlsagEKLKCLQLEKEKILQ 800
Cdd:COG4942    11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA-------RRIRALEQELAALEA 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  801 DLACVTRDRGDIHNQLtamcRKKEALNEELMRTRQRLEQTTETNSRLN-RNLEEMVKDVEEKQVVIDLHEKDTHRLNELL 879
Cdd:COG4942    84 ELAELEKEIAELRAEL----EAQKEELAELLRALYRLGRQPPLALLLSpEDFLDAVRRLQYLKYLAPARREQAEELRADL 159

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 665394924  880 AALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLLNAARAAE 957
Cdd:COG4942   160 AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 929-1194 2.18e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  929 ARLQKELEQCQRKAQETKtQLLNAARAAESDFNQKIANLQACAEEAAKRhgeeilqlRNALEKRMQQALQALQTAKDdEI 1008
Cdd:COG4942    23 AEAEAELEQLQQEIAELE-KELAALKKEEKALLKQLAALERRIAALARR--------IRALEQELAALEAELAELEK-EI 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1009 EKLQERLATLQAHLESLVQqheeALIRAESEKQQALLIAHRDKQAVAERLEAVsrdlkteqesldrsrREANARDEKQRA 1088
Cdd:COG4942    93 AELRAELEAQKEELAELLR----ALYRLGRQPPLALLLSPEDFLDAVRRLQYL---------------KYLAPARREQAE 153

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1089 AIAQLKDEMVQMRTKEEEHKIKLEEcirkqelQLSSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGE 1168
Cdd:COG4942   154 ELRADLAELAALRAELEAERAELEA-------LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELE 226

                         250       260
                  ....*....|....*....|....*.
gi 665394924 1169 GFIDSLRKELTDCRRQLADSNIERDK 1194
Cdd:COG4942   227 ALIARLEAEAAAAAERTPAAGFAALK 252
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 828-1704 2.21e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 49.79  E-value: 2.21e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   828 EELMRTRQRLEQTTETNSRLNRNLEEMVKDV----EEKQVVIDLHEKDTHRLNE---LLAALRSEKESLESVLFDTNTSL 900
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKAESELKELEKKHqqlcEEKNALQEQLQAETELCAEaeeMRARLAARKQELEEILHELESRL 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   901 EATEERRSQLE----------RDLQEALVREESLKNhvaRLQ----------KELEQCQRKAQETKTQLLNAARAAESDF 960
Cdd:pfam01576   85 EEEEERSQQLQnekkkmqqhiQDLEEQLDEEEAARQ---KLQlekvtteakiKKLEEDILLLEDQNSKLSKERKLLEERI 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   961 NQKIANLqACAEEAAK-----RHGEEI----LQLRNALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQQhee 1031
Cdd:pfam01576  162 SEFTSNL-AEEEEKAKslsklKNKHEAmisdLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQ--- 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1032 aLIRAESEKQQALLIAHR---DKQAVAERLEAVSRDLKTEQESLDrSRREANARDEKQRAaiaQLKDEMVQMRTKEEE-- 1106
Cdd:pfam01576  238 -LAKKEEELQAALARLEEetaQKNNALKKIRELEAQISELQEDLE-SERAARNKAEKQRR---DLGEELEALKTELEDtl 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1107 -HKIKLEECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDrmeSTNNELQDALRKSKEGEGFIDSLRKELTDCRRQL 1185
Cdd:pfam01576  313 dTTAAQQELRSKREQEVTELKKALEEETRSHEAQLQEMRQKHT---QALEELTEQLEQAKRNKANLEKAKQALESENAEL 389

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1186 AdsnIERDKYSGSNKELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNAT 1265
Cdd:pfam01576  390 Q---AELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSL 466

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1266 KAQLQKAQ--------------VEFAQKDEGGKELQCKLVAEVELKERAQQELCQIKKQLSDLEanlcaTRQELGRARCQ 1331
Cdd:pfam01576  467 ESQLQDTQellqeetrqklnlsTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMK-----KKLEEDAGTLE 541

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1332 NNQEEHRFHAREQE-LAQRLEEGRGREKRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDEQLScvelhkrdTE 1410
Cdd:pfam01576  542 ALEEGKKRLQRELEaLTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLA--------EE 613

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1411 QKLSSVVHTLRRIAGIQvdgSVNLSHRLLSPSRRFSPSRSCGDYDNRSTSQCPDGPIDV--DPDLVRKGVRNLMHQVAQL 1488
Cdd:pfam01576  614 KAISARYAEERDRAEAE---AREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLvsSKDDVGKNVHELERSKRAL 690

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1489 EREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQA-------------------MLRNLQEEKSNLETDRKMKISAIQ 1549
Cdd:pfam01576  691 EQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAqferdlqardeqgeekrrqLVKQVRELEAELEDERKQRAQAVA 770

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1550 A--------------LEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDN---EKRQLQEELA 1612
Cdd:pfam01576  771 AkkkleldlkeleaqIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNleaELLQLQEDLA 850

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1613 KVEGRASKLELQRVAMEGDL-------TRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERL---- 1681
Cdd:pfam01576  851 ASERARRQAQQERDELADEIasgasgkSALQDEKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELaaer 930

                          970       980
                   ....*....|....*....|....*.
gi 665394924  1682 ---QKSAVSETQLRGEIKTLQKELSE 1704
Cdd:pfam01576  931 stsQKSESARQQLERQNKELKAKLQE 956
COG5022 COG5022
Myosin heavy chain [General function prediction only];
604-1263 2.24e-05

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 49.69  E-value: 2.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  604 SDYEKMQLNCGKLQKRIDSMEEDKKAVE-LEIQRILKDKNITELNLRSEEDRSSRLREETIslreeLNRVSLNRDLLEQQ 682
Cdd:COG5022   787 VDYELKWRLFIKLQPLLSLLGSRKEYRSyLACIIKLQKTIKREKKLRETEEVEFSLKAEVL-----IQKFGRSLKAKKRF 861

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  683 RIESDNLINLLEKQKSDLeydldkllLEKcDLQEKHEklsnnSCSTSDELKSVQNCLQE-----AQEERKKLRIQSVDQC 757
Cdd:COG5022   862 SLLKKETIYLQSAQRVEL--------AER-QLQELKI-----DVKSISSLKLVNLELESeiielKKSLSSDLIENLEFKT 927

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  758 NEIGELKKelaILDKARLELETDNLSAGEKLKCLQLEKEKILQDLAcvtRDRGDIHNQLTAMCRKKEALNEELMRTRQRL 837
Cdd:COG5022   928 ELIARLKK---LLNNIDLEEGPSIEYVKLPELNKLHEVESKLKETS---EEYEDLLKKSTILVREGNKANSELKNFKKEL 1001

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  838 EQTTETNSRLnrnlEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLESVlfdTNTSLEATEERRS----QLERD 913
Cdd:COG5022  1002 AELSKQYGAL----QESTKQLKELPVEVAELQSASKIISSESTELSILKPLQKLK---GLLLLENNQLQARykalKLRRE 1074

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  914 LQEALVREESLKNHVARLQKELEQcqRKAQETKTQLLNAARAAE--------SDFNQKIA-----NLQACAEEAAKRHGE 980
Cdd:COG5022  1075 NSLLDDKQLYQLESTENLLKTINV--KDLEVTNRNLVKPANVLQfivaqmikLNLLQEISkflsqLVNTLEPVFQKLSVL 1152

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  981 EILQLRNALEKRMQQALQALQTAKDDEIEKLQERLATLQAHL-ESLVQQHEEALIRAESEKQQALLIAHRDKQAVAErle 1059
Cdd:COG5022  1153 QLELDGLFWEANLEALPSPPPFAALSEKRLYQSALYDEKSKLsSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISE--- 1229

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1060 avSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECIRK-------------QELQLSSLR 1126
Cdd:COG5022  1230 --GWVPTEYSTSLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEEEVLPATinsllqyinvglfNALRTKASS 1307

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1127 EERESLCRVSEELKMEIR-LKEDRMESTNNELQDALRKSKEGEGFIDSL--RKELTDCRRQLADSNIER--DKYSGSNKE 1201
Cdd:COG5022  1308 LRWKSATEVNYNSEELDDwCREFEISDVDEELEELIQAVKVLQLLKDDLnkLDELLDACYSLNPAEIQNlkSRYDPADKE 1387

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 665394924 1202 L---RDHVKRVES--AKREQA------RAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLN 1263
Cdd:COG5022  1388 NnlpKEILKKIEAllIKQELQlslegkDETEVHLSEIFSEEKSLISLDRNSIYKEEVLSSLSALLTKEKIALL 1460
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1576-1780 2.35e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 2.35e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1576 LAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCSIRQMAERLEN 1655
Cdd:COG4942    15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1656 QNRALTQLEDRCTAL------KSTVDQLKERLQKSAVSETQLRGE-IKTLQKELSEQGHCSQANEDKLKLVQKSLQTAEN 1728
Cdd:COG4942    95 LRAELEAQKEELAELlralyrLGRQPPLALLLSPEDFLDAVRRLQyLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 665394924 1729 EKRILTERLDSAQTNLNELRRSQQAQLDGNQR----LQEQVTDLEVQRSALESQLR 1780
Cdd:COG4942   175 ELEALLAELEEERAALEALKAERQKLLARLEKelaeLAAELAELQQEAEELEALIA 230
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 811-1423 3.33e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 48.86  E-value: 3.33e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   811 DIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLE 890
Cdd:TIGR04523   58 NLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENK 137

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   891 SVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLLNaaraaesdFNQKIANLQAc 970
Cdd:TIGR04523  138 KNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLK--------LELLLSNLKK- 208

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   971 AEEAAKRHGEEILQLrnaleKRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEEAlIRAESEKQQALLIAHRd 1050
Cdd:TIGR04523  209 KIQKNKSLESQISEL-----KKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKI-KKQLSEKQKELEQNNK- 281

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1051 kqaVAERLEAVSRDLKTEQESLDRsrreanardEKQRAAIAQLKDEMVQMRTKEEEHKIKL---EECIRKQELQLSSLRE 1127
Cdd:TIGR04523  282 ---KIKELEKQLNQLKSEISDLNN---------QKEQDWNKELKSELKNQEKKLEEIQNQIsqnNKIISQLNEQISQLKK 349

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1128 ERESLCRVSEELKMEIRLKEDRMESTNNElqdalrkskegegfIDSLRKELTDCRRQLADSNIERDKYSGSNKELRDHVK 1207
Cdd:TIGR04523  350 ELTNSESENSEKQRELEEKQNEIEKLKKE--------------NQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIK 415

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1208 RVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDL-------NATKAQLQKAQVEFAQKD 1280
Cdd:TIGR04523  416 KLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLkvlsrsiNKIKQNLEQKQKELKSKE 495

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1281 EGGKEL----------QCKLVAEV-ELKERAQQ---ELCQIKKQLSDLEANLCATRQELGRARC-----QNNQEEHRFHA 1341
Cdd:TIGR04523  496 KELKKLneekkeleekVKDLTKKIsSLKEKIEKlesEKKEKESKISDLEDELNKDDFELKKENLekeidEKNKEIEELKQ 575

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1342 REQELAQRLEEGRGREKRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTEQKLSSVVHTLR 1421
Cdd:TIGR04523  576 TQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIK 655


                   ..
gi 665394924  1422 RI 1423
Cdd:TIGR04523  656 EI 657
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 879-1092 3.91e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 48.29  E-value: 3.91e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  879 LAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQE---------TKTQL 949
Cdd:COG3883    25 LSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGEraralyrsgGSVSY 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  950 LNAARAAES--DFNQKIANLQACAEEAAkrhgeEILQLRNALEKRMQQALQALQTAKdDEIEKLQERLATLQAHLESLVQ 1027
Cdd:COG3883   105 LDVLLGSESfsDFLDRLSALSKIADADA-----DLLEELKADKAELEAKKAELEAKL-AELEALKAELEAAKAELEAQQA 178

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 665394924 1028 QHEEALIRAESEKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQ 1092
Cdd:COG3883   179 EQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 243
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 213-683 4.85e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.78  E-value: 4.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  213 AAELCRKLEEEHQRCEQIVAQNSALRQQLEESNRTNEALTNDLQKLTNDWASLRDELLIKEDEFKEEEQAFKDYYNSEHN 292
Cdd:COG1196   311 RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  293 RLLKMwREVVAVKRSFKEMQTAMKAEVAKMGQEINcvgkdingSNATVAFAVQQAKRAADDELKQSQRSNDELQNQLATL 372
Cdd:COG1196   391 ALRAA-AELAAQLEELEEAEEALLERLERLEEELE--------ELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  373 KVQYESARHEIMERDQRLLELMNQLKKLEDRCAQAESQAALASRYSDEIER--LNNSMREIAQAV--VQDAENADREADA 448
Cdd:COG1196   462 LELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAalLLAGLRGLAGAVavLIGVEAAYEAALE 541

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  449 EVTGGVMQHMHLTRDAASVVGGAGGAGSTAGGGGKSPRRNSTRASQAFAEGTISAVQAALHKYQLALHDMQVKFQNTSET 528
Cdd:COG1196   542 AALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  529 LRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSELLQERESLQRGLDDIRVQKQQSEMGRADINSAFENLSSDYEK 608
Cdd:COG1196   622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLA 701

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 665394924  609 MQLNCGKLQKRIDSMEEDKKAVELEIQRILKDKNITELNLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQR 683
Cdd:COG1196   702 EEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1083-1841 5.13e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.53  E-value: 5.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1083 DEKQRAAIAQLKdemvQMRTKEEEHKIKLEECIRkqelQLSSLREERESLCRVSEELKmeiRLKEDRMESTNNELQDALR 1162
Cdd:TIGR02169  169 DRKKEKALEELE----EVEENIERLDLIIDEKRQ----QLERLRREREKAERYQALLK---EKREYEGYELLKEKEALER 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1163 KSKEGEGFIDSLRKELTDCRRQLADSNierDKYSGSNKELRDHVKRVESAKREQARAIEEALQkisnledtknSLENERT 1242
Cdd:TIGR02169  238 QKEAIERQLASLEEELEKLTEEISELE---KRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIG----------ELEAEIA 304

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1243 RLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKELQCKLVAEVELKERAQQELCQIKKQLSDLEANLCATR 1322
Cdd:TIGR02169  305 SLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1323 QELGRARCQNNQEEHRFHAREQELAQRLEEGRGREKRLEDqkhnLEVCLADATQQIQELKARLGGAEGRIRALDEQLSCV 1402
Cdd:TIGR02169  385 DELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAD----LNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQL 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1403 ELHKRDTEQKLSSVVHTLRRIAGIQVDGSVNLSHrlLSPSRRFSPSRSCGDYDNRstsqcpdgpidvdpDLVRKGVRNLM 1482
Cdd:TIGR02169  461 AADLSKYEQELYDLKEEYDRVEKELSKLQRELAE--AEAQARASEERVRGGRAVE--------------EVLKASIQGVH 524

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1483 HQVAQLEREKDDYKSQLGAA----------KKQLQDAADQQLRCDAKLGKLQAM----LRNLQEEKSNLETDRKMKIsAI 1548
Cdd:TIGR02169  525 GTVAQLGSVGERYATAIEVAagnrlnnvvvEDDAVAKEAIELLKRRKAGRATFLplnkMRDERRDLSILSEDGVIGF-AV 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1549 QALEEKLKHRNDECQMLRERLAQTEMQLAatseengqneerleksrqqcskldnekrqlqeelakvegRASKLELQRVAM 1628
Cdd:TIGR02169  604 DLVEFDPKYEPAFKYVFGDTLVVEDIEAA---------------------------------------RRLMGKYRMVTL 644

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1629 EGDL---------------TRLQMALQEKDcSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQLRG 1693
Cdd:TIGR02169  645 EGELfeksgamtggsraprGGILFSRSEPA-ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEK 723

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1694 EIKTLQKELSEQGHCSQANEDKLKLVQKSLQTAENEKRILTERLDSAQTNLNELRR---SQQAQLDGN--QRLQEQVTDL 1768
Cdd:TIGR02169  724 EIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEalnDLEARLSHSriPEIQAELSKL 803

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 665394924  1769 EVQRSALESQLRiakwnqesggdkdltngngggngeeELSRQLKSSQREKSELRSKLQTLQDKVKQLECDRKS 1841
Cdd:TIGR02169  804 EEEVSRIEARLR-------------------------EIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKS 851
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 527-1079 5.24e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.68  E-value: 5.24e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   527 ETLRTTKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSE-LLQERESLQRGLDDIR-------------VQKQQSEMgR 592
Cdd:pfam12128  347 EQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEqNNRDIAGIKDKLAKIReardrqlavaeddLQALESEL-R 425

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   593 ADINSAFENLSSDYEKMQLNCGKLQKRIDSM---EEDKKAVELEIQRI------LKDKNITELNLRSEEDRSSRLREE-T 662
Cdd:pfam12128  426 EQLEAGKLEFNEEEYRLKSRLGELKLRLNQAtatPELLLQLENFDERIerareeQEAANAEVERLQSELRQARKRRDQaS 505

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   663 ISLREELNRVSLNR---DLLEQQRI-ESDNLINLLEKQKSDLEYDLDKL----LLEKCDLqekHEKLSNNSCSTSDELKS 734
Cdd:pfam12128  506 EALRQASRRLEERQsalDELELQLFpQAGTLLHFLRKEAPDWEQSIGKVispeLLHRTDL---DPEVWDGSVGGELNLYG 582

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   735 VQNCLQeaqeerkklRIQSVDQCNEIGELKKELAILDKArleletdnlsageklkcLQLEKEKILQDLACVTRDRGDIHN 814
Cdd:pfam12128  583 VKLDLK---------RIDVPEWAASEEELRERLDKAEEA-----------------LQSAREKQAAAEEQLVQANGELEK 636

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   815 QLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLHEKDThrLNELLAALRSEKESLESVLF 894
Cdd:pfam12128  637 ASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQL--DKKHQAWLEEQKEQKREART 714

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   895 DTNTSLEATEErrsqlERDLQEALVREESLKNHVARlQKELEQCQrkaQETKTQL--LNAARAAESDFNQKIANLQACAE 972
Cdd:pfam12128  715 EKQAYWQVVEG-----ALDAQLALLKAAIAARRSGA-KAELKALE---TWYKRDLasLGVDPDVIAKLKREIRTLERKIE 785

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   973 EAAKRhGEEILQLRNALEKRMQQALQALQTAKDD---EIEKLQERLATLQAHLESLVQQHEEAliRAESEKQQALLI-AH 1048
Cdd:pfam12128  786 RIAVR-RQEVLRYFDWYQETWLQRRPRLATQLSNierAISELQQQLARLIADTKLRRAKLEME--RKASEKQQVRLSeNL 862

                          570       580       590
                   ....*....|....*....|....*....|.
gi 665394924  1049 RDKQAVAERLEAVSRDLKTEQESLDRSRREA 1079
Cdd:pfam12128  863 RGLRCEMSKLATLKEDANSEQAQGSIGERLA 893
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1200-1415 8.58e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 8.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1200 KELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKaQVEFAQK 1279
Cdd:COG4942    37 AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAE-LLRALYR 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1280 DEGGKELQCKLVAE-VELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEhrfhareQELAQRLEEGRGREK 1358
Cdd:COG4942   116 LGRQPPLALLLSPEdFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER-------AELEALLAELEEERA 188

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 665394924 1359 RLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTEQKLSS 1415
Cdd:COG4942   189 ALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1496-1780 9.43e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 47.43  E-value: 9.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1496 KSQLGAAKKQLQDAADQQLRCDAKLGKLqAMLRNLQEEKSNLEtDRKMKISAIqaleeklkhRNDECQMLRERLAQTEMQ 1575
Cdd:pfam17380  315 RRKLEEAEKARQAEMDRQAAIYAEQERM-AMERERELERIRQE-ERKRELERI---------RQEEIAMEISRMRELERL 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1576 LAATSEENGQNEERLEKSRQQcsKLDNEKRQLQEELAKVEGRASKLElQRVAMEGDLTRLQMALQEKDCSIRQMAERLEN 1655
Cdd:pfam17380  384 QMERQQKNERVRQELEAARKV--KILEEERQRKIQQQKVEMEQIRAE-QEEARQREVRRLEEERAREMERVRLEEQERQQ 460

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1656 QNRALTQLEDRCTALKSTVDQLKErlqKSAVSETQLRgeiKTLQKELSEQGHCSQANEDKLKLVQKSLQtaENEKRILTE 1735
Cdd:pfam17380  461 QVERLRQQEEERKRKKLELEKEKR---DRKRAEEQRR---KILEKELEERKQAMIEEERKRKLLEKEME--ERQKAIYEE 532

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*
gi 665394924  1736 RldsaQTNLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQLR 1780
Cdd:pfam17380  533 E----RRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMER 573
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1056-1768 9.55e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 47.66  E-value: 9.55e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1056 ERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTkeEEHKIKLEECIRKQELQLSSLREERESLCRV 1135
Cdd:TIGR00618  164 EKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCT--PCMPDTYHERKQVLEKELKHLREALQQTQQS 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1136 SEELKMEIRLKEDRmESTNNELQDALRKSKEGEGFIDSLrkELTDCRRQLADSNIERDKYSGSNKELRDHVKRVESAKRE 1215
Cdd:TIGR00618  242 HAYLTQKREAQEEQ-LKKQQLLKQLRARIEELRAQEAVL--EETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQS 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1216 QARAIEEALQKISNLEDTKNSLENERTRLSTILKEtENHFTKTTQDLNATKAQLQKAqvefaqkdeggKELQCKLVAEVE 1295
Cdd:TIGR00618  319 KMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQ-EIHIRDAHEVATSIREISCQQ-----------HTLTQHIHTLQQ 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1296 LKERAQQELcQIKKQLSDLEANLCATRQELgrarcqnnqeehrfHAREQELAQRLEEGRGREKRledQKHNLEVCLADAT 1375
Cdd:TIGR00618  387 QKTTLTQKL-QSLCKELDILQREQATIDTR--------------TSAFRDLQGQLAHAKKQQEL---QQRYAELCAAAIT 448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1376 QQIQELKAR---LGGAEGRIRALDEQLSCVELHKRDTEQKLSSVVHTLRRIAGIQVDGSVNLSHrllspsrrfsPSRSCG 1452
Cdd:TIGR00618  449 CTAQCEKLEkihLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIH----------PNPARQ 518

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1453 DYDNRSTSQCPDGPIDVDPDLVRKGVRNLMHQVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQE 1532
Cdd:TIGR00618  519 DIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQD 598

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1533 EKSNLETDRKMKISAIQALEEKLKHRND------ECQMLRERLAQTEMQLAATSEENGQNEERlEKSRQQCSKLDNEKRQ 1606
Cdd:TIGR00618  599 LTEKLSEAEDMLACEQHALLRKLQPEQDlqdvrlHLQQCSQELALKLTALHALQLTLTQERVR-EHALSIRVLPKELLAS 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1607 LQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTA----LKSTVDQLKERLQ 1682
Cdd:TIGR00618  678 RQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDAlnqsLKELMHQARTVLK 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1683 KSAVSETQLRGEIKTLQKELSEQGHCSQANEDKLKLVQKSL-QTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRL 1761
Cdd:TIGR00618  758 ARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDThLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRL 837


                   ....*..
gi 665394924  1762 QEQVTDL 1768
Cdd:TIGR00618  838 EEKSATL 844
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 657-1095 1.26e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 47.25  E-value: 1.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  657 RLREETISLREELnrvslnRDLLEQQRIESDNLINL------LEKQKSDLEYDLD------KLLLEKCDLQEKHEKLSNN 724
Cdd:COG3096   282 ELSERALELRREL------FGARRQLAEEQYRLVEMareleeLSARESDLEQDYQaasdhlNLVQTALRQQEKIERYQED 355

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  725 SCSTSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDKARLELETDNLSAGEKLKclQLEKEKILQDLAc 804
Cdd:COG3096   356 LEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQ--ALEKARALCGLP- 432

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  805 vtrdrgdihnQLTAmcrkkEALNEELMRTRQRLEQTTETnsrlnrnleemVKDVEEKQVVIDLHEKDTHRLNELLAALRS 884
Cdd:COG3096   433 ----------DLTP-----ENAEDYLAAFRAKEQQATEE-----------VLELEQKLSVADAARRQFEKAYELVCKIAG 486

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  885 EKEslesvlfdtntSLEATEERRSQLE--RDLQEALVREESLKNHVARLQKELEQcQRKAQETKTQlLNAARAAESDFNQ 962
Cdd:COG3096   487 EVE-----------RSQAWQTARELLRryRSQQALAQRLQQLRAQLAELEQRLRQ-QQNAERLLEE-FCQRIGQQLDAAE 553

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  963 KIANLQACAEEAAKRHGEeilQLRNALEKRM--QQALQALQtAKDDEIEKLQERLATLQAHLESLVQQHEEALIRAESek 1040
Cdd:COG3096   554 ELEELLAELEAQLEELEE---QAAEAVEQRSelRQQLEQLR-ARIKELAARAPAWLAAQDALERLREQSGEALADSQE-- 627

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 665394924 1041 qqalLIAHRDKQAVAERLEAVSRD-LKTEQESLDRSRREANARDEKQRAAIAQLKD 1095
Cdd:COG3096   628 ----VTAAMQQLLEREREATVERDeLAARKQALESQIERLSQPGGAEDPRLLALAE 679
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 786-1016 1.60e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 1.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  786 EKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQvvi 865
Cdd:COG4942    27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK--- 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  866 dlhekdtHRLNELLAAL-RSEKESLESVLFDTNTSLEAteERRSQLERDLQEALVRE-ESLKNHVARLQKeleqcQRKAQ 943
Cdd:COG4942   104 -------EELAELLRALyRLGRQPPLALLLSPEDFLDA--VRRLQYLKYLAPARREQaEELRADLAELAA-----LRAEL 169

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 665394924  944 ETKTQLLNAARAAESDFNQKIANLQACAEEAAKRHGEEILQLRNALekrmqQALQALQTAKDDEIEKLQERLA 1016
Cdd:COG4942   170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAEL-----AELQQEAEELEALIARLEAEAA 237
PTZ00121 PTZ00121
MAEBL; Provisional
 971-1773 1.65e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.06  E-value: 1.65e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  971 AEEAAKRHGEEILQLRNALE--KRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAH 1048
Cdd:PTZ00121 1100 AEEAKKTETGKAEEARKAEEakKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAE 1179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1049 RDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMV----QMRTKEEE----HKIKLEECIRKQEL 1120
Cdd:PTZ00121 1180 AARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVkkaeEAKKDAEEakkaEEERNNEEIRKFEE 1259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1121 QLSSLREERESLCRVSEELKM-EIRLKEDRMEStnnelqDALRKSKEGEGfIDSLRKELTDCRRqladSNIERDKYSGSN 1199
Cdd:PTZ00121 1260 ARMAHFARRQAAIKAEEARKAdELKKAEEKKKA------DEAKKAEEKKK-ADEAKKKAEEAKK----ADEAKKKAEEAK 1328

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1200 KELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQlQKAQVEFAQK 1279
Cdd:PTZ00121 1329 KKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAK-KKAEEDKKKA 1407

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1280 DEGGKELQCKLVAEvELKERAQQelcqiKKQLSDLEAnlcatrqelgRARCQNNQEEHRFHAREQELAQRLEEGRGREKR 1359
Cdd:PTZ00121 1408 DELKKAAAAKKKAD-EAKKKAEE-----KKKADEAKK----------KAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKK 1471

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1360 LEDQKHNlevclADATQQIQELKARlggAEGRIRALDEQLSCVELHKRDTEQKLSsvvhtlrriagiqvdgsvnlshrll 1439
Cdd:PTZ00121 1472 ADEAKKK-----AEEAKKADEAKKK---AEEAKKKADEAKKAAEAKKKADEAKKA------------------------- 1518

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1440 spsrrfspsrscgdydnrstsqcpdgpidvdpDLVRKGVrnlmhqvaqlEREKDDYKSQLGAAKKQLQDAADQQLRCDAK 1519
Cdd:PTZ00121 1519 --------------------------------EEAKKAD----------EAKKAEEAKKADEAKKAEEKKKADELKKAEE 1556

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1520 LGKLQAMLRnlQEEKSNLETDRKMKISAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSK 1599
Cdd:PTZ00121 1557 LKKAEEKKK--AEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKK 1634

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1600 LDNEKRQLQEELAKVEgrasklELQRVAMEGDLTRLQMALQ-EKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLK 1678
Cdd:PTZ00121 1635 VEQLKKKEAEEKKKAE------ELKKAEEENKIKAAEEAKKaEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELK 1708

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1679 ERLQKSAVSETQLRGEiKTLQKELSEQGHcSQANEDKLKlvQKSLQTAENEKRILTERLDSAQTNLNELRRSQQAQLDGN 1758
Cdd:PTZ00121 1709 KKEAEEKKKAEELKKA-EEENKIKAEEAK-KEAEEDKKK--AEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE 1784

                         810
                  ....*....|....*
gi 665394924 1759 QRLQEQVTDLEVQRS 1773
Cdd:PTZ00121 1785 LDEEDEKRRMEVDKK 1799
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 849-1377 1.68e-04

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 46.67  E-value: 1.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   849 RNLEEMVKdvEEKQVVIDLHEKD----THRLNELLAALRSEKESLESvlfdtntSLEATEERRSQLERDLQEALVREESL 924
Cdd:pfam07111  132 KNLEEGSQ--RELEEIQRLHQEQlsslTQAHEEALSSLTSKAEGLEK-------SLNSLETKRAGEAKQLAEAQKEAELL 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   925 KNHVARLQKELEqcqrkAQETKTQLLN--AARAAESDFNQKIANLQACAEEAAKRHGEEILQLRNALEKRMQQALQALQT 1002
Cdd:pfam07111  203 RKQLSKTQEELE-----AQVTLVESLRkyVGEQVPPEVHSQTWELERQELLDTMQHLQEDRADLQATVELLQVRVQSLTH 277

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1003 AKDDEIEKLQERLATLQAhLESLVQQHEEALIRAESEKQQALLIA-------HRD-----KQAVAERLEAVSRDlKTEQE 1070
Cdd:pfam07111  278 MLALQEEELTRKIQPSDS-LEPEFPKKCRSLLNRWREKVFALMVQlkaqdleHRDsvkqlRGQVAELQEQVTSQ-SQEQA 355

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1071 SLDRSRREANARDEKQRAAIAQLKDEMVQMrtkeeehkiklEECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDRM 1150
Cdd:pfam07111  356 ILQRALQDKAAEVEVERMSAKGLQMELSRA-----------QEARRRQQQQTASAEEQLKFVVNAMSSTQIWLETTMTRV 424

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1151 E-------STNNELQDALRKSKEGEGFIDS----LRKELTDCRRQLADSNIERDkYSGSNKELRDHVKRVESAKREQARA 1219
Cdd:pfam07111  425 EqavaripSLSNRLSYAVRKVHTIKGLMARkvalAQLRQESCPPPPPAPPVDAD-LSLELEQLREERNRLDAELQLSAHL 503

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1220 IEEALQKisnledTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKELQCKLVAEVELKER 1299
Cdd:pfam07111  504 IQQEVGR------AREQGEAERQQLSEVAQQLEQELQRAQESLASVGQQLEVARQGQQESTEEAASLRQELTQQQEIYGQ 577

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1300 AQQELC-----QIKKQLSDLEANLCATRQELGRARCQNNQEEHRfHAREQELAQRL---------EEGRGREKRLEDQKH 1365
Cdd:pfam07111  578 ALQEKVaevetRLREQLSDTKRRLNEARREQAKAVVSLRQIQHR-ATQEKERNQELrrlqdearkEEGQRLARRVQELER 656

                          570
                   ....*....|..
gi 665394924  1366 NLEVCLADATQQ 1377
Cdd:pfam07111  657 DKNLMLATLQQE 668
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1483-1700 1.72e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.55  E-value: 1.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1483 HQVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMkisaiqaleeklkhrndec 1562
Cdd:COG3206   205 NGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQSPVI------------------- 265

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1563 QMLRERLAQTEMQLAATSEENGQNEERLEKSRQQcskLDNEKRQLQEELAKVegrASKLELQRVAMEGDLTRLQMALQEk 1642
Cdd:COG3206   266 QQLRAQLAELEAELAELSARYTPNHPDVIALRAQ---IAALRAQLQQEAQRI---LASLEAELEALQAREASLQAQLAQ- 338

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 665394924 1643 dcsIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQK 1700
Cdd:COG3206   339 ---LEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNVRVIDP 393
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 901-1162 1.92e-04

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 46.75  E-value: 1.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  901 EATEERRSQLERDLQEALvreeslkNHVARLQKELEQCQRKAQETKTQLLNAARAAESdfNQKIANLQACAE------EA 974
Cdd:NF012221 1565 ERAEADRQRLEQEKQQQL-------AAISGSQSQLESTDQNALETNGQAQRDAILEES--RAVTKELTTLAQgldaldSQ 1635

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  975 AKRHGEEILQLRN----ALEKRMQQALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALL-IAHR 1049
Cdd:NF012221 1636 ATYAGESGDQWRNpfagGLLDRVQEQLDDAKKISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQGEQNQANAEQdIDDA 1715

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1050 DKQAVAERLEAVSRDLKTEQEsldRSRREANARDEKQR----AAIAQLKDEMVQMRTKeeehKIKLEECIR--KQELQLS 1123
Cdd:NF012221 1716 KADAEKRKDDALAKQNEAQQA---ESDANAAANDAQSRgeqdASAAENKANQAQADAK----GAKQDESDKpnRQGAAGS 1788

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 665394924 1124 -------SLREERESLCRVSEELKMEI--RLKEDRMESTNNELQDALR 1162
Cdd:NF012221 1789 glsgkaySVEGVAEPGSHINPDSPAAAdgRFSEGLTEQEQEALEGATN 1836
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1645-1851 2.22e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 2.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1645 SIRQMAERLENQNRALTQLEDRCtalkstvdqlkERLQKSAVSETQLRGEIKTLQKELSEQghCSQANEDKLKLVQKSLQ 1724
Cdd:COG4913   239 RAHEALEDAREQIELLEPIRELA-----------ERYAAARERLAELEYLRAALRLWFAQR--RLELLEAELEELRAELA 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1725 TAENEKRILTERLDSAQTNLNELRRsQQAQLDGNQ--RLQEQVTDLEVQ-------RSALESQLRIAKWNQESGGDKDLT 1795
Cdd:COG4913   306 RLEAELERLEARLDALREELDELEA-QIRGNGGDRleQLEREIERLEREleererrRARLEALLAALGLPLPASAEEFAA 384

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 665394924 1796 NGNGGGNGEEELSRQLKSSQREKSELRSKLQTLQDKVKQLECDRKSKFSGGNAYDR 1851
Cdd:COG4913   385 LRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPA 440
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
832-1046 2.23e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.16  E-value: 2.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  832 RTRQRLEQTTETNSRLNRNLEEMVKDVEEKQV-VIDLHEK-DTHRLNELLAALRSEKESLESVLFDTNTSLEATEERRSQ 909
Cdd:COG3206   165 NLELRREEARKALEFLEEQLPELRKELEEAEAaLEEFRQKnGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAA 244

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  910 LERDLQEALVREESLKNH--VARLQKELEQCQRKAQETKTQLLN------AARAAESDFNQKIANLQACAEEAAKRHGEE 981
Cdd:COG3206   245 LRAQLGSGPDALPELLQSpvIQQLRAQLAELEAELAELSARYTPnhpdviALRAQIAALRAQLQQEAQRILASLEAELEA 324

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 665394924  982 ILQLRNALEKRMQQALQALQTAKDDEIE--KLQERLATLQAHLESLVQQHEEALIRAESEKQQALLI 1046
Cdd:COG3206   325 LQAREASLQAQLAQLEARLAELPELEAElrRLEREVEVARELYESLLQRLEEARLAEALTVGNVRVI 391
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1096-1238 2.26e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 46.39  E-value: 2.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1096 EMVQMRTKEEEHKIKLEECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKE---GEGFID 1172
Cdd:COG2433   396 EAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEERREIRKDREisrLDREIE 475

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 665394924 1173 SLRKELTDCRRqladsnierdkysgSNKELRDHVKRVESAKREQARAIEEALQKISNLedTKNSLE 1238
Cdd:COG2433   476 RLERELEEERE--------------RIEELKRKLERLKELWKLEHSGELVPVKVVEKF--TKEAIR 525
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1039-1417 2.27e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 46.04  E-value: 2.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1039 EKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEEcirkq 1118
Cdd:pfam07888   38 ECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEE----- 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1119 elqlssLREERESLCRVSEELKMEIRLKEDRMESTNNELQDA---LRKSKEGEGFIDSLRKELTDCRRQLadsnieRDKY 1195
Cdd:pfam07888  113 ------LSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLEReteLERMKERAKKAGAQRKEEEAERKQL------QAKL 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1196 SGSNKELRDHVKRVESAKREQARAIEEALQkisnledtknsLENERTRLSTILKETENHftktTQDLNATKAQLQKAQVE 1275
Cdd:pfam07888  181 QQTEEELRSLSKEFQELRNSLAQRDTQVLQ-----------LQDTITTLTQKLTTAHRK----EAENEALLEELRSLQER 245

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1276 FAQKDEGGKELQCKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEHRF-------HAREQELA- 1347
Cdd:pfam07888  246 LNASERKVEGLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLALREGRARWAQERETLqqsaeadKDRIEKLSa 325

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1348 --QRLEEgRGREKRLEDQKHNLE---------VCLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTEQKLSSV 1416
Cdd:pfam07888  326 elQRLEE-RLQEERMEREKLEVElgrekdcnrVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLETV 404


                   .
gi 665394924  1417 V 1417
Cdd:pfam07888  405 A 405
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 772-1399 2.39e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 46.58  E-value: 2.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   772 KARLELETDNLSAGEKLKCLQLEKE--KILQDLACVTRDR-GDIHNQLTA---MCRKKEALNEELMRTRQRLEQTTETNS 845
Cdd:TIGR00606  186 KALETLRQVRQTQGQKVQEHQMELKylKQYKEKACEIRDQiTSKEAQLESsreIVKSYENELDPLKNRLKEIEHNLSKIM 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   846 RLNRNLE-------EMVKDVEE-KQVVIDLHEKDTHRLNELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEA 917
Cdd:TIGR00606  266 KLDNEIKalksrkkQMEKDNSElELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTEL 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   918 LVREESLKNHVARLQKELEQCQRKAQETKTQLLNAARAAESDFNQKIANLQACAEEAAKRHGEEILQLRNALEKRMQQAL 997
Cdd:TIGR00606  346 LVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQ 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   998 QALQTAKDDE------IEKLQERLATLQAHLESLVQQHEEALIRAES--EKQQALLIAHR-----DKQAVAERLEAVSRD 1064
Cdd:TIGR00606  426 EQADEIRDEKkglgrtIELKKEILEKKQEELKFVIKELQQLEGSSDRilELDQELRKAERelskaEKNSLTETLKKEVKS 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1065 LKTEQESLDRS-RREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECIRKQEL---------------QLSSLREE 1128
Cdd:TIGR00606  506 LQNEKADLDRKlRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELtsllgyfpnkkqledWLHSKSKE 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1129 ----RESLCRV------SEELKMEIRLKEDRMESTNNELQDALRK---SKEGEGFIDSLRKELTDCRRQLA--------- 1186
Cdd:TIGR00606  586 inqtRDRLAKLnkelasLEQNKNHINNELESKEEQLSSYEDKLFDvcgSQDEESDLERLKEEIEKSSKQRAmlagatavy 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1187 DSNIER--DKYSG----------SNKELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSL-------ENERTRLSTI 1247
Cdd:TIGR00606  666 SQFITQltDENQSccpvcqrvfqTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMlglapgrQSIIDLKEKE 745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1248 LKETENHFTKTTQDLNATKAQLQKAQVEFAQ---KDEGGKELQcklvAEVELKERAQQELCQIKKQLSDLEANLCATrqE 1324
Cdd:TIGR00606  746 IPELRNKLQKVNRDIQRLKNDIEEQETLLGTimpEEESAKVCL----TDVTIMERFQMELKDVERKIAQQAAKLQGS--D 819

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 665394924  1325 LGRARCQNNQEEHRFHAREQELAQRLEEGRgreKRLEDQKHNLEVcLADATQQIQELKARLGGAEGRIRALDEQL 1399
Cdd:TIGR00606  820 LDRTVQQVNQEKQEKQHELDTVVSKIELNR---KLIQDQQEQIQH-LKSKTNELKSEKLQIGTNLQRRQQFEEQL 890
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1603-1836 3.18e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.82  E-value: 3.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1603 EKRQLQEELAKVEG---RASKLELQRVAMEGDLTRLQMALQEKDCSIR------QMAERLENQNRALTQLE-----DRCT 1668
Cdd:TIGR02168  156 ERRAIFEEAAGISKykeRRKETERKLERTRENLDRLEDILNELERQLKslerqaEKAERYKELKAELRELElallvLRLE 235

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1669 ALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEQGHCSQANEDKLKLVQKSLQTA-------ENEKRILTERLDSAQ 1741
Cdd:TIGR02168  236 ELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALaneisrlEQQKQILRERLANLE 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1742 TN-------LNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQL---RIAKWNQESGGDKDLTNGNGGGNGEEELSRQL 1811
Cdd:TIGR02168  316 RQleeleaqLEELESKLDELAEELAELEEKLEELKEELESLEAELeelEAELEELESRLEELEEQLETLRSKVAQLELQI 395

                          250       260
                   ....*....|....*....|....*
gi 665394924  1812 KSSQREKSELRSKLQTLQDKVKQLE 1836
Cdd:TIGR02168  396 ASLNNEIERLEARLERLEDRRERLQ 420
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1487-1836 3.57e-04

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 45.27  E-value: 3.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1487 QLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEEKLKhrndecqMLR 1566
Cdd:pfam07888   70 QWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEARIRELEEDIK-------TLT 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1567 ERLAQTEMQLAatseengQNEERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKDCSI 1646
Cdd:pfam07888  143 QRVLERETELE-------RMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTI 215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1647 RQMAERLENQNRALTQLEDRCTALKStvdqLKERLQKSAVSETQLRGEIKTLqKELSEQGHCS------QANEDKLKLVQ 1720
Cdd:pfam07888  216 TTLTQKLTTAHRKEAENEALLEELRS----LQERLNASERKVEGLGEELSSM-AAQRDRTQAElhqarlQAAQLTLQLAD 290

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1721 KSLQTAENEKRILTERlDSAQTNLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQLRIAKwnqesggDKDLTNGNGG 1800
Cdd:pfam07888  291 ASLALREGRARWAQER-ETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEVELGREK-------DCNRVQLSES 362

                          330       340       350
                   ....*....|....*....|....*....|....*.
gi 665394924  1801 GNGEEELSRQLKSSQREKSELRSKLQTLQDKVKQLE 1836
Cdd:pfam07888  363 RRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLE 398
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1656-1842 3.68e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1656 QNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEQghcsqanEDKLKLVQKSLQTAENEKRILTE 1735
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAL-------ARRIRALEQELAALEAELAELEK 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1736 RLDSAQTNLNELRRSQQAQLDGNQRLQEQ--VTDLEVQRSALESQLRIAKWNQESGGDKDLTNGNGGGNGEeeLSRQLKS 1813
Cdd:COG4942    91 EIAELRAELEAQKEELAELLRALYRLGRQppLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE--LAALRAE 168

                         170       180
                  ....*....|....*....|....*....
gi 665394924 1814 SQREKSELRSKLQTLQDKVKQLECDRKSK 1842
Cdd:COG4942   169 LEAERAELEALLAELEEERAALEALKAER 197
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 532-1202 4.56e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 45.34  E-value: 4.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   532 TKAQLETSEGTKQLLTTKMQQLTEKLDSSNSKLSELLQERESLQRGLDDIRVQKQQsemgRADINSAfENLSSDYEKMQL 611
Cdd:TIGR00618  210 TPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQL----RARIEEL-RAQEAVLEETQE 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   612 NCGKLQKRIDSMEEDKKAVELEIQRILKDKNITELNLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQRIESDNLIN 691
Cdd:TIGR00618  285 RINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVA 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   692 LLEKQKSDLEYDLDKLLLEKCDLQEKHEKLSNNSCSTSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILD 771
Cdd:TIGR00618  365 TSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCA 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   772 ----------KARLELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAMCRKKEALNEELMRTRQRLEQTT 841
Cdd:TIGR00618  445 aaitctaqceKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   842 ETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESlESVLFDTNTSLEATEERRSQLERDLQEALVRE 921
Cdd:TIGR00618  525 PLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQS-FSILTQCDNRSKEDIPNLQNITVRLQDLTEKL 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   922 ESLKNHVARLQKELEQcQRKAQETKTQLLNAARAAESDFNQKIANLQACAEEAAKRHGEEILQLRNALEKRMQQALQALQ 1001
Cdd:TIGR00618  604 SEAEDMLACEQHALLR-KLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLAL 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1002 TAKDDEIEKLQERLATLqAHLESLVQQHEEALIRAESEKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLD---RSRRE 1078
Cdd:TIGR00618  683 QKMQSEKEQLTYWKEML-AQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARtvlKARTE 761

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1079 ANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECIRKQELQLSSLREERESlcrVSEELKMEIRLKEDRMESTNNElq 1158
Cdd:TIGR00618  762 AHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPS---DEDILNLQCETLVQEEEQFLSR-- 836

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....
gi 665394924  1159 daLRKSKEGEGFIDSLRKELTDCRRQLADSNIERDKYSGSNKEL 1202
Cdd:TIGR00618  837 --LEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
759-1187 4.57e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 4.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  759 EIGELKKELAILDKARLELEtdnlSAGEKLKCLQLEKEKILQDLACVTRDRgdihnQLTAMCRKKEALNEELMRTRQRLE 838
Cdd:COG4717    79 ELKEAEEKEEEYAELQEELE----ELEEELEELEAELEELREELEKLEKLL-----QLLPLYQELEALEAELAELPERLE 149

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  839 QttetnsrlnrnLEEMVKDVEEKQVVIDLHEKDTHRL-NELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEA 917
Cdd:COG4717   150 E-----------LEERLEELRELEEELEELEAELAELqEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEA 218

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  918 LVREESLKNHVARLQKELEQCQRKAQETKTQLLNAARAAESDFNQKIANLQACAEEAAK----RHGEEILQLRNALEKRM 993
Cdd:COG4717   219 QEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGvlflVLGLLALLFLLLAREKA 298

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  994 QQALQALQTAKDDEIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAHRDKQAVAERLEavsrdLKTEQESLD 1073
Cdd:COG4717   299 SLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ-----LEELEQEIA 373

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1074 RSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEEciRKQELQLSSLREERESLCRVSEELKMEIRLKEDRMEST 1153
Cdd:COG4717   374 ALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEE--LLGELEELLEALDEEELEEELEELEEELEELEEELEEL 451

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 665394924 1154 NNELQDALRKSK--EGEGFIDSLRKELTDCRRQLAD 1187
Cdd:COG4717   452 REELAELEAELEqlEEDGELAELLQELEELKAELRE 487
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 727-956 4.66e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 4.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  727 STSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQDLAcvt 806
Cdd:COG4942    24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE--- 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  807 RDRGDIHNQLTAMCRKKEALNEELM-------RTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELL 879
Cdd:COG4942   101 AQKEELAELLRALYRLGRQPPLALLlspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 665394924  880 AALRSEKESLESvlfdtntSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLLNAARAA 956
Cdd:COG4942   181 AELEEERAALEA-------LKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAA 250
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1206-1780 5.27e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.03  E-value: 5.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1206 VKRVESAKREQARAIEEALQKI--SNLEDTKNSLENERTRLSTILKETENHFTK---TTQDLNATKAQLQKAQVEFAQKD 1280
Cdd:PRK02224  178 VERVLSDQRGSLDQLKAQIEEKeeKDLHERLNGLESELAELDEEIERYEEQREQareTRDEADEVLEEHEERREELETLE 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1281 EGGKELQCKLVAEVELKERAQQELCQIKKQLSDLEANLCATRQELGRARCQNNQEEHR---FHAREQELAQRLEEGR--- 1354
Cdd:PRK02224  258 AEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARreeLEDRDEELRDRLEECRvaa 337

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1355 -----------GREKRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTEQKLSSVVHTLRRI 1423
Cdd:PRK02224  338 qahneeaeslrEDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEEL 417

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1424 AgiQVDGSVNLSHRLLSPSRRFSPSRSCGDYDNRSTSQCPDGPIDVDPDLVRKGVRNLMHQVAQLEREKDDYKSQLGAAK 1503
Cdd:PRK02224  418 R--EERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVE 495

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1504 KQLQDAADqqlrcdakLGKLQAMLRNLQEEKSNLEtdrkmkiSAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSEEN 1583
Cdd:PRK02224  496 ERLERAED--------LVEAEDRIERLEERREDLE-------ELIAERRETIEEKRERAEELRERAAELEAEAEEKREAA 560

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1584 GQNEERLEKSRQQCSKLDNEKRQLQEELAKVEgrasklelqrvamegDLTRLQMALQEKDCSIRQMAERLENQNRALTQL 1663
Cdd:PRK02224  561 AEAEEEAEEAREEVAELNSKLAELKERIESLE---------------RIRTLLAAIADAEDEIERLREKREALAELNDER 625

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1664 EDRCTALKSTVDQLKERLQKSAVSETQLRGE-IKTLQKELSEQGHCSQANEDKLklvQKSLQTAENEkrilTERLDSaqt 1742
Cdd:PRK02224  626 RERLAEKRERKRELEAEFDEARIEEAREDKErAEEYLEQVEEKLDELREERDDL---QAEIGAVENE----LEELEE--- 695

                         570       580       590
                  ....*....|....*....|....*....|....*...
gi 665394924 1743 nLNELRRSQQAQLDGNQRLQEQVTDLEVQRSALESQLR 1780
Cdd:PRK02224  696 -LRERREALENRVEALEALYDEAEELESMYGDLRAELR 732
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1099-1287 5.54e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 5.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1099 QMRTKEEEHKIKLEECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKEL 1178
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1179 TDCRRQLAD--------SNIERDKYSGSNKELRDHVKRVESAK---REQARAIEEALQKISNLEDTKNSLENERTRLSTI 1247
Cdd:COG4942   100 EAQKEELAEllralyrlGRQPPLALLLSPEDFLDAVRRLQYLKylaPARREQAEELRADLAELAALRAELEAERAELEAL 179

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 665394924 1248 LKETENHFTKTTQDLNATKAQLQKAQVEFAQKDEGGKELQ 1287
Cdd:COG4942   180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQ 219
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1043-1281 5.83e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 5.83e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1043 ALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKiKLEECIRKQELQL 1122
Cdd:COG4942     7 LALLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIR-ALEQELAALEAEL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1123 SSLREERESLCRVSEELKMEI--RLKEDRMESTNNELQdALRKSKEGEGFIDSLR--KELTDCRRQLADSnIERDKysgs 1198
Cdd:COG4942    86 AELEKEIAELRAELEAQKEELaeLLRALYRLGRQPPLA-LLLSPEDFLDAVRRLQylKYLAPARREQAEE-LRADL---- 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1199 nKELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVEFAQ 1278
Cdd:COG4942   160 -AELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238


                  ...
gi 665394924 1279 KDE 1281
Cdd:COG4942   239 AAE 241
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 879-1053 5.94e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.76  E-value: 5.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  879 LAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLLNAARAAEs 958
Cdd:COG1579    12 LQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKE- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  959 dfnqkIANLQACAEEAAKRhgeeilqlRNALEKRMQQALQALQTAKdDEIEKLQERLATLQAHLESLVQQHEEALirAES 1038
Cdd:COG1579    91 -----YEALQKEIESLKRR--------ISDLEDEILELMERIEELE-EELAELEAELAELEAELEEKKAELDEEL--AEL 154

                         170
                  ....*....|....*
gi 665394924 1039 EKQQALLIAHRDKQA 1053
Cdd:COG1579   155 EAELEELEAEREELA 169
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
911-1132 6.61e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 6.61e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  911 ERDLQEALvreESLKNHVARLqKELEQCQRKAQETKTQLLNAARAAESdfnqkianLQACAEEAAKRHgeeilQLRNALE 990
Cdd:COG4913   220 EPDTFEAA---DALVEHFDDL-ERAHEALEDAREQIELLEPIRELAER--------YAAARERLAELE-----YLRAALR 282

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  991 -KRMQQALQALQtakdDEIEKLQERLATLQAHLESLVQQHEEAliraeSEKQQALLIAHRdkQAVAERLEAVSRDLKTEQ 1069
Cdd:COG4913   283 lWFAQRRLELLE----AELEELRAELARLEAELERLEARLDAL-----REELDELEAQIR--GNGGDRLEQLEREIERLE 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1070 ESLDRSRREANARDE-----------------KQRAAIAQLKDEMVQMRTKEEEHKIKLEECIRKQELQLSSLREERESL 1132
Cdd:COG4913   352 RELEERERRRARLEAllaalglplpasaeefaALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASL 431
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1119-1279 6.68e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.37  E-value: 6.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1119 ELQLSSLREERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNierdkysgS 1198
Cdd:COG1579    16 DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVR--------N 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1199 NKELRDHVKRVESAKREQARA---IEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQLQKAQVE 1275
Cdd:COG1579    88 NKEYEALQKEIESLKRRISDLedeILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREE 167


                  ....
gi 665394924 1276 FAQK 1279
Cdd:COG1579   168 LAAK 171
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1440-1739 7.75e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 44.51  E-value: 7.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1440 SPSRRfsPSRSCGDYDNRSTSQCPDGPIDVDPDLVRKGVRNLMHQ---VAQLEREKDDYKsqlgaaKKQLQDAADQQLRC 1516
Cdd:PLN02939   55 APKQR--SSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHnraSMQRDEAIAAID------NEQQTNSKDGEQLS 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1517 DAKLGKLQAMLRNLQEeksNLETDRKMKISAIQALEEKLKHRND---ECQMLRERLAQTEMQLAATSEENGQ---NEERL 1590
Cdd:PLN02939  127 DFQLEDLVGMIQNAEK---NILLLNQARLQALEDLEKILTEKEAlqgKINILEMRLSETDARIKLAAQEKIHveiLEEQL 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1591 EKSRQQCSK-------------------------LDNEKRQLQEEL---AKVEGRASKLELQRVAMEGDLTRLQM----- 1637
Cdd:PLN02939  204 EKLRNELLIrgateglcvhslskeldvlkeenmlLKDDIQFLKAELievAETEERVFKLEKERSLLDASLRELESkfiva 283

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1638 -------------ALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQ------LRGEIKTL 1698
Cdd:PLN02939  284 qedvsklsplqydCWWEKVENLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLEASLKEANVSKFSsykvelLQQKLKLL 363

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 665394924 1699 QKELSEqghCSQANEDKLKLVQKSLQ---------TAENEKRILTERLDS 1739
Cdd:PLN02939  364 EERLQA---SDHEIHSYIQLYQESIKefqdtlsklKEESKKRSLEHPADD 410
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1331-1558 8.46e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 8.46e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1331 QNNQEEHRFHAREQELAQRLEEGRGREKRLEDQKHNLEVCLADATQQIQELKARLGGAEGRIRALDEQLSCVELHKRDTE 1410
Cdd:COG4942    24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQK 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1411 QKLSsvvhtlRRIAGIQVDGSVNLSHRLLSPS------RRFSPSRSCGDYDNRSTSQcpdgpidvdpdlVRKGVRNLMHQ 1484
Cdd:COG4942   104 EELA------ELLRALYRLGRQPPLALLLSPEdfldavRRLQYLKYLAPARREQAEE------------LRADLAELAAL 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 665394924 1485 VAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEEKLKHR 1558
Cdd:COG4942   166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 497-1121 1.00e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.34  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   497 AEGTISAVQAALHKYQLALHDMQVKFQNTSETLRTTKAQLETS-EGTKQLLTTKMQQLTEKLDSSNSKLSELLQERESLQ 575
Cdd:pfam15921  290 ARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSElREAKRMYEDKIEELEKQLVLANSELTEARTERDQFS 369

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   576 RGLDDIRVQKQQSemgRADINSAFENLSSDYEKmqlncgklQKRIDSMEEDKKAVELEIQRILKDKNITELNLrsEEDRS 655
Cdd:pfam15921  370 QESGNLDDQLQKL---LADLHKREKELSLEKEQ--------NKRLWDRDTGNSITIDHLRRELDDRNMEVQRL--EALLK 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   656 SRLREETISLREELNRVSLNRDLLEQqrieSDNLINLLEKQKSDLEYDLDKLLLEKCDLQEKHEKLSNNSCStsdeLKSV 735
Cdd:pfam15921  437 AMKSECQGQMERQMAAIQGKNESLEK----VSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTAS----LQEK 508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   736 QNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQdlacVTRDRGDIHNQ 815
Cdd:pfam15921  509 ERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIEN----MTQLVGQHGRT 584

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   816 LTAMCRKKEALNEELMRTRQRLEQTTETNSRLN---RNLEEMVKDVEEKQVvidlheKDTHRLNELLAALRSEKESLESV 892
Cdd:pfam15921  585 AGAMQVEKAQLEKEINDRRLELQEFKILKDKKDakiRELEARVSDLELEKV------KLVNAGSERLRAVKDIKQERDQL 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   893 LFDTNTSleateerRSQLERDLQEALVREESLKNhvarlqkELEQCQRKAQETKTQLlnaaRAAESDFNQKIANLQACae 972
Cdd:pfam15921  659 LNEVKTS-------RNELNSLSEDYEVLKRNFRN-------KSEEMETTTNKLKMQL----KSAQSELEQTRNTLKSM-- 718

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   973 EAAKRHGeeilqlrnaleKRMQQALQALQTAKDDEIEKLQERLATLQAHLESlvQQHEEALIRAESEK-QQALLIAHRDK 1051
Cdd:pfam15921  719 EGSDGHA-----------MKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTN--ANKEKHFLKEEKNKlSQELSTVATEK 785

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1052 QAVAERLEAvsrdLKTEQESLDRSRREANARDEKQRAAIAQLKDemVQMRTKEEEHKIKLEECIRKQELQ 1121
Cdd:pfam15921  786 NKMAGELEV----LRSQERRLKEKVANMEVALDKASLQFAECQD--IIQRQEQESVRLKLQHTLDVKELQ 849
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 700-1314 1.00e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.44  E-value: 1.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   700 LEYDLDKLLLEKCDLQEKHEKLSNNSCSTSDELKSVQnclqEAQEERKKLRIQSVDQCNEI-----GELKKELAILDKAR 774
Cdd:pfam12128  246 LQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQ----ETSAELNQLLRTLDDQWKEKrdelnGELSAADAAVAKDR 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   775 LELEtdnLSAGEKLKCLQLEKEKILQDLACVTrdrgDIHNQLTAMCRKKEALneelmrTRQRLEQTTETNSRLNRNLEEM 854
Cdd:pfam12128  322 SELE---ALEDQHGAFLDADIETAAADQEQLP----SWQSELENLEERLKAL------TGKHQDVTAKYNRRRSKIKEQN 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   855 VKDVEekqvvidlhekdthRLNELLAALRSEKESLESVLFDTNTSLEAteERRSQLERDLQEALVREESLKNHVARLQKE 934
Cdd:pfam12128  389 NRDIA--------------GIKDKLAKIREARDRQLAVAEDDLQALES--ELREQLEAGKLEFNEEEYRLKSRLGELKLR 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   935 LEQCQrKAQETKTQL-------------LNAARAAESDFNQKIANLQACAEEAAKRHGEE---ILQLRNALEKRMQQA-- 996
Cdd:pfam12128  453 LNQAT-ATPELLLQLenfderierareeQEAANAEVERLQSELRQARKRRDQASEALRQAsrrLEERQSALDELELQLfp 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   997 -----LQALQTAKDDEIEKLQERLATLQAHLESLV-----------------------------QQHEEALIRAESEKQQ 1042
Cdd:pfam12128  532 qagtlLHFLRKEAPDWEQSIGKVISPELLHRTDLDpevwdgsvggelnlygvkldlkridvpewAASEEELRERLDKAEE 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1043 ALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECIRKQELQL 1122
Cdd:pfam12128  612 ALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQL 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1123 SSLREE----RESLCRVSEELKMEIRLKEDRMESTNNELQDALR--KSKEGEGFIDSLRKELTDCRRQLADSNIERDKYS 1196
Cdd:pfam12128  692 KQLDKKhqawLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKaaIAARRSGAKAELKALETWYKRDLASLGVDPDVIA 771

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1197 GSNKELRDHVKRVESAKREQARAI-------EEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATKAQL 1269
Cdd:pfam12128  772 KLKREIRTLERKIERIAVRRQEVLryfdwyqETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKAS 851

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*..
gi 665394924  1270 QKAQVEFAQKDEGGKELQCKL--VAEVELKERAQQELCQIKKQLSDL 1314
Cdd:pfam12128  852 EKQQVRLSENLRGLRCEMSKLatLKEDANSEQAQGSIGERLAQLEDL 898
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
599-1163 1.10e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  599 FENLSSDYEKMQlncgKLQKRIDSMEE--------DKKAVELEIQRILKDKniteLNLRSEEDRSSRLREETISLREELN 670
Cdd:COG4913   234 FDDLERAHEALE----DAREQIELLEPirelaeryAAARERLAELEYLRAA----LRLWFAQRRLELLEAELEELRAELA 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  671 RVSLNRDLLEQQRIESDNLINLLEKQKSDLEYDlDKLLLEKcdlqekheklsnnscstsdELKSVQNCLQEAQEERKKLR 750
Cdd:COG4913   306 RLEAELERLEARLDALREELDELEAQIRGNGGD-RLEQLER-------------------EIERLERELEERERRRARLE 365

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  751 iqsvDQCNEIG-ELKKELAILDKARLELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAMCRKKEALNEE 829
Cdd:COG4913   366 ----ALLAALGlPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPAR 441

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  830 LMRTRQRLEqttetnsrlnrnlEEMVKDVEEKQVV---IDLHEKD---------------------THRLNELLAALRSE 885
Cdd:COG4913   442 LLALRDALA-------------EALGLDEAELPFVgelIEVRPEEerwrgaiervlggfaltllvpPEHYAAALRWVNRL 508

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  886 KESLESVLFDTNTSLEatEERRSQLERDlqeALVREESLKNHVAR--LQKELEQ-----CQRKAQETKT---------QL 949
Cdd:COG4913   509 HLRGRLVYERVRTGLP--DPERPRLDPD---SLAGKLDFKPHPFRawLEAELGRrfdyvCVDSPEELRRhpraitragQV 583

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  950 LNAARAAESDFNQKIANLQACAEEAAKRhgeeilqlRNALEKRMQQALQALQTAkDDEIEKLQERLATLQAHLESL--VQ 1027
Cdd:COG4913   584 KGNGTRHEKDDRRRIRSRYVLGFDNRAK--------LAALEAELAELEEELAEA-EERLEALEAELDALQERREALqrLA 654

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1028 QHEEALIRAesekqQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAA---IAQLKDEMVQMRTKE 1104
Cdd:COG4913   655 EYSWDEIDV-----ASAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELkgeIGRLEKELEQAEEEL 729

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 665394924 1105 EEHKIKLEECIRKQELQLSSLREER-------ESLCRVSEELKMEIRLKEDRMESTNNELQDALRK 1163
Cdd:COG4913   730 DELQDRLEAAEDLARLELRALLEERfaaalgdAVERELRENLEERIDALRARLNRAEEELERAMRA 795
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 626-1201 1.16e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.94  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   626 DKKAVELEIQRILKDKNITELNLRSEEDRSsRLREETISLREELNRVSLNRDLLEQQRIESDN----LINLLEKQKSDLE 701
Cdd:pfam05483  193 EKMILAFEELRVQAENARLEMHFKLKEDHE-KIQHLEEEYKKEINDKEKQVSLLLIQITEKENkmkdLTFLLEESRDKAN 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   702 YDLDKLLLEKCDLQEKHEKLSNNSCSTSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDKAR------- 774
Cdd:pfam05483  272 QLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKaahsfvv 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   775 LELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAMCR---KKEALNEELMRTRQRLEQTTETNSRLNRNL 851
Cdd:pfam05483  352 TEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKfknNKEVELEELKKILAEDEKLLDEKKQFEKIA 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   852 EEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARL 931
Cdd:pfam05483  432 EELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDM 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   932 QKELEQCQRKAQETKTQ---LLNAARAAESDFNQKIANLQACAEEAAKRHGEEILQLRNALEKRMQQALQALQTAKDDEI 1008
Cdd:pfam05483  512 TLELKKHQEDIINCKKQeerMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYEVLKKEKQMKI 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1009 EK-----LQERLATLQAHLESLvQQHEEALIRAESEKQQALLIAHRDKQAVAERLEAVSRDLKT-----EQESLDRSRRE 1078
Cdd:pfam05483  592 LEnkcnnLKKQIENKNKNIEEL-HQENKALKKKGSAENKQLNAYEIKVNKLELELASAKQKFEEiidnyQKEIEDKKISE 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1079 ANARDEKQRAAIaqLKDEMVQMRT---KEEEHKI-KLEECIRKQELQLSSLREERESlcrvseelkmEIRLKEDRMEStn 1154
Cdd:pfam05483  671 EKLLEEVEKAKA--IADEAVKLQKeidKRCQHKIaEMVALMEKHKHQYDKIIEERDS----------ELGLYKNKEQE-- 736

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 665394924  1155 nelQDALRKSKEGEgfIDSLRKELTDCRRQLADSNIERDKYSGSNKE 1201
Cdd:pfam05483  737 ---QSSAKAALEIE--LSNIKAELLSLKKQLEIEKEEKEKLKMEAKE 778
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1472-1841 1.18e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.90  E-value: 1.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1472 DLVRKGVRNLMHQVAQLEREKDDY---KSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKmKISAI 1548
Cdd:PRK03918  210 NEISSELPELREELEKLEKEVKELeelKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVK-ELKEL 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1549 QALEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEERL---EKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQR 1625
Cdd:PRK03918  289 KEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIkelEEKEERLEELKKKLKELEKRLEELEERHELYEEAK 368

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1626 VAMEgDLTRLQMalQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQ--KSAVSETQ-LRGEIKTLQKEL 1702
Cdd:PRK03918  369 AKKE-ELERLKK--RLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKelKKAIEELKkAKGKCPVCGREL 445

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1703 SEQGHCSQANEDKLKL--VQKSLQTAENEKRILTERLDSAQTNLNELRRsqqaqLDGNQRLQEQVTDLEVQRSALESQLR 1780
Cdd:PRK03918  446 TEEHRKELLEEYTAELkrIEKELKEIEEKERKLRKELRELEKVLKKESE-----LIKLKELAEQLKELEEKLKKYNLEEL 520

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 665394924 1781 IAKWnqesggdKDLTNGNGGGNGEEELSRQLKSSQREKSELRSKLQTLQDKVKQLECDRKS 1841
Cdd:PRK03918  521 EKKA-------EEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAE 574
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1546-1842 1.21e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.90  E-value: 1.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1546 SAIQALEEKLKHRNDECQMLRERLAQTEmqlaATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLElqr 1625
Cdd:PRK03918  162 NAYKNLGEVIKEIKRRIERLEKFIKRTE----NIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELE--- 234

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1626 vAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKErLQKSAVSETQLRGEIKTLQKELSEQ 1705
Cdd:PRK03918  235 -ELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKE-LKEKAEEYIKLSEFYEEYLDELREI 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1706 GHCSQANEDKLKLVQKSLQTAENEKriltERLDSAQTNLNELRRsQQAQLDGNQRLQEQVTDLEVQRSALESQLRIakwn 1785
Cdd:PRK03918  313 EKRLSRLEEEINGIEERIKELEEKE----ERLEELKKKLKELEK-RLEELEERHELYEEAKAKKEELERLKKRLTG---- 383

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 665394924 1786 qesggdkdltngngggNGEEELSRQLKSSQREKSELRSKLQTLQDKVKQLECDRKSK 1842
Cdd:PRK03918  384 ----------------LTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKEL 424
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 904-1131 1.24e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.28  E-value: 1.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  904 EERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLlNAARAAESDFNQKIANLQacaeeaakrhgEEIL 983
Cdd:COG3883    15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAEL-EALQAEIDKLQAEIAEAE-----------AEIE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  984 QLRNALEKRMQQA---------LQALQTAKD--DEIEKLQeRLATLQAHLESLVQQHEEALIRAESEKQQalliahrdkq 1052
Cdd:COG3883    83 ERREELGERARALyrsggsvsyLDVLLGSESfsDFLDRLS-ALSKIADADADLLEELKADKAELEAKKAE---------- 151

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 665394924 1053 avaerLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEmvqmRTKEEEHKIKLEECIRKQELQLSSLREERES 1131
Cdd:COG3883   152 -----LEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAE----EAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221
Gp58 pfam07902
gp58-like protein; Sequences found in this family are derived from a number of bacteriophage ...
 336-604 1.43e-03

gp58-like protein; Sequences found in this family are derived from a number of bacteriophage and prophage proteins. They are similar to gp58, a minor structural protein of Lactococcus delbrueckii bacteriophage LL-H.


Pssm-ID: 369586 [Multi-domain]  Cd Length: 594  Bit Score: 43.79  E-value: 1.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   336 SNATVAFAVQQAKRAADDELKQSQRSNDELQNqlatLKVQYESARHEIMERDQRLLELMNQLKKLEDRCAQAESQAA--- 412
Cdd:pfam07902  123 KTEIVESAEGIATRISEDTDKKLALINETISG----IRREYQDADRQLSSSYQAGIEGLKATMASDKIGLQAEIQASaqg 198

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   413 LASRYSDEIERLNNSMREIAQAVVQDAENADREADAEVTggvmqhmhlTRDAASVVGGAGGAGSTAGGGGKSPRRNSTRA 492
Cdd:pfam07902  199 LSQRYDNEIRKLSAKITTTSSGTTEAYESKLDDLRAEFT---------RSNQGMRTELESKISGLQSTQQSTAYQISQEI 269

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   493 SQafAEGTISAVQAALHKYQLALHDMQVKFQNTSETLRTTKAQLETSEGTkqlLTTKMQQLTEKLDSSNSKlsellQERE 572
Cdd:pfam07902  270 SN--REGAVSRVQQDLDSYQRRLQDAEKNYSSLTQTVKGLQSTVSDPNSK---LESRITQLAGLIEQKVTR-----GDVE 339

                          250       260       270
                   ....*....|....*....|....*....|....*..
gi 665394924   573 SLQRGLDD-----IRVQKQQSEMGRADINSAFeNLSS 604
Cdd:pfam07902  340 SIIRQSGDsimlaIKAKLPQSKMSGSEIISAI-NLNG 375
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1545-1734 1.54e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.97  E-value: 1.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1545 ISAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQ 1624
Cdd:COG4372    37 LFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEE 116

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1625 RVAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQksAVSETQLRGEIKTLQKELSE 1704
Cdd:COG4372   117 LEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQ--ALSEAEAEQALDELLKEANR 194

                         170       180       190
                  ....*....|....*....|....*....|
gi 665394924 1705 QGHCSQANEDKLKLVQKSLQTAENEKRILT 1734
Cdd:COG4372   195 NAEKEEELAEAEKLIESLPRELAEELLEAK 224
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 213-780 1.56e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.77  E-value: 1.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  213 AAELCRKLEEEHQRCEQIVAQNSALRQQLEESNRTNEALTNDLQKLTNDWASLRDELLIKEDEFKEEEQafkdyynsEHN 292
Cdd:COG1196   248 LEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE--------RLE 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  293 RLLKMWREVVAVKRSFKEMQTAMKAEVAKMGQEINcvgkdingsnatvafAVQQAKRAADDELKQSQRSNDELQNQLATL 372
Cdd:COG1196   320 ELEEELAELEEELEELEEELEELEEELEEAEEELE---------------EAEAELAEAEEALLEAEAELAEAEEELEEL 384

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  373 KVQYESARHEIMERDQRLLELMNQLKKLEDRCAQAESQAALAsrySDEIERLNNSMREIAQAVVQDAENADREADAEVTg 452
Cdd:COG1196   385 AEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEEL---EEALAELEEEEEEEEEALEEAAEEEAELEEEEEA- 460

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  453 gvMQHMHLTRDAASVVGGAGGAGSTAGGGGKSPRRNSTRASQAFAEGTISAVQAALHKYQLALHDMQVKfqntseTLRTT 532
Cdd:COG1196   461 --LLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVA------VLIGV 532

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  533 KAQLETSEGTkqLLTTKMQQLTEKLDSSNSKLSELLQereslqrglddirvQKQQSEMGRADINSAFENLSSDYEKMQLN 612
Cdd:COG1196   533 EAAYEAALEA--ALAAALQNIVVEDDEVAAAAIEYLK--------------AAKAGRATFLPLDKIRARAALAAALARGA 596

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  613 CGKLQKRIDSMEEDKKAVELEIQRILKDKNITELNLRSEEDRSSRLREETISLREELNRVSLNRDLLEQQRIESDNLINL 692
Cdd:COG1196   597 IGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE 676

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  693 LEKQKSDLEYDLDKLLLEKCDLQEKHEKLSNNScstsdELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDK 772
Cdd:COG1196   677 AEAELEELAERLAEEELELEEALLAEEEEEREL-----AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751


                  ....*...
gi 665394924  773 ARLELETD 780
Cdd:COG1196   752 ALEELPEP 759
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
770-1141 1.64e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.97  E-value: 1.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  770 LDKARLELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRGDIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNR 849
Cdd:COG4372     8 VGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNE 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  850 NLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLESvlfdtntSLEATEERRSQLERDLQEALVREESLKNHVA 929
Cdd:COG4372    88 QLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQ-------QRKQLEAQIAELQSEIAEREEELKELEEQLE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  930 RLQKELEQCQRKAQETKTQLLnaaraaesdfNQKIANLQACAEEAAKRHGEEILQLRNALEKRMQQALQALQTAKDDEIE 1009
Cdd:COG4372   161 SLQEELAALEQELQALSEAEA----------EQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAK 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1010 KLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAA 1089
Cdd:COG4372   231 LGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLI 310

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 665394924 1090 IAQLKDEMVQMRTKEEEHKIKLEECIRKQELQLSSLREERESLCRVSEELKM 1141
Cdd:COG4372   311 GALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLSKG 362
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
842-963 1.82e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 43.31  E-value: 1.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  842 ETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLEsvlfdtnTSLEATEERRSQLERDL------- 914
Cdd:COG2433   385 LIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELE-------AELEEKDERIERLERELsearsee 457

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 665394924  915 -QEALVREE--SLKNHVARLQKELEQCQRKAQETKTQLLNAARAAESDFNQK 963
Cdd:COG2433   458 rREIRKDREisRLDREIERLERELEEERERIEELKRKLERLKELWKLEHSGE 509
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1467-1632 2.11e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 2.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1467 IDVDPDLVRKGVRNLMHQVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKis 1546
Cdd:COG1579    15 LDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEYE-- 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1547 AIQALEEKLKHRNDEcqmLRERLAQTEMQLAATSEENGQNEERLEKSRQQcskLDNEKRQLQEELAKVEGRASKLELQRV 1626
Cdd:COG1579    93 ALQKEIESLKRRISD---LEDEILELMERIEELEEELAELEAELAELEAE---LEEKKAELDEELAELEAELEELEAERE 166


                  ....*.
gi 665394924 1627 AMEGDL 1632
Cdd:COG1579   167 ELAAKI 172
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 981-1132 2.15e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 2.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  981 EILQLRNALEKRMQ--QALQALQTAKDDEIEKLQERLATLQ---AHLESLVQQHEEALirAESEKQQALLIAHRDKQAVA 1055
Cdd:COG1579    18 ELDRLEHRLKELPAelAELEDELAALEARLEAAKTELEDLEkeiKRLELEIEEVEARI--KKYEEQLGNVRNNKEYEALQ 95

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 665394924 1056 ERLEAvsrdLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECIRKQELQLSSLREERESL 1132
Cdd:COG1579    96 KEIES----LKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREEL 168
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1503-1843 2.53e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 43.09  E-value: 2.53e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1503 KKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSEE 1582
Cdd:TIGR04523   81 EQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNK 160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1583 NgqneerlEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKDcsirqmaerlenqnraltQ 1662
Cdd:TIGR04523  161 Y-------NDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNK------------------S 215

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1663 LEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEQGHCSQANEDKLKLVQKSLQTAENEKRILTERLDSAQT 1742
Cdd:TIGR04523  216 LESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKS 295

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1743 NLNELRrsQQAQLDGNQRLQEQVTDLEVQRSALESQL-----RIAKWNQEsggdkdltngngggngEEELSRQLKSSQRE 1817
Cdd:TIGR04523  296 EISDLN--NQKEQDWNKELKSELKNQEKKLEEIQNQIsqnnkIISQLNEQ----------------ISQLKKELTNSESE 357

                          330       340
                   ....*....|....*....|....*.
gi 665394924  1818 KSELRSKLQTLQDKVKQLECDRKSKF 1843
Cdd:TIGR04523  358 NSEKQRELEEKQNEIEKLKKENQSYK 383
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 1478-1580 2.71e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 42.76  E-value: 2.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1478 VRNLMHQVAQLEREKDdyksqlgAAKKQlQDAADQQlrcdaKLGKLQAMLRNLQEEKSNLETD---RKMKISAIQALEEK 1554
Cdd:COG0542   413 LDELERRLEQLEIEKE-------ALKKE-QDEASFE-----RLAELRDELAELEEELEALKARweaEKELIEEIQELKEE 479

                          90       100
                  ....*....|....*....|....*.
gi 665394924 1555 LKHRNDECQMLRERLAQTEMQLAATS 1580
Cdd:COG0542   480 LEQRYGKIPELEKELAELEEELAELA 505
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 799-1108 3.03e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 42.36  E-value: 3.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   799 LQDLACVTRDRGDIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNEL 878
Cdd:pfam19220   19 LEDLRSLKADFSQLIEPIEAILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAA 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   879 LAALRSEKESLESVLFDTNTSLEAteerrsqLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLlNAARAAES 958
Cdd:pfam19220   99 LREAEAAKEELRIELRDKTAQAEA-------LERQLAAETEQNRALEEENKALREEAQAAEKALQRAEGEL-ATARERLA 170

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   959 DFNQKIANLQACAEEAAkrhgEEILQLRNALEKRMQQALQALQTakddeIEKLQERLATLQAHLESLVQQHEEALIRAES 1038
Cdd:pfam19220  171 LLEQENRRLQALSEEQA----AELAELTRRLAELETQLDATRAR-----LRALEGQLAAEQAERERAEAQLEEAVEAHRA 241

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1039 EKQqalliahrdkqAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHK 1108
Cdd:pfam19220  242 ERA-----------SLRMKLEALTARAAATEQLLAEARNQLRDRDEAIRAAERRLKEASIERDTLERRLA 300
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 811-985 3.11e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.45  E-value: 3.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  811 DIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKEsLE 890
Cdd:COG1579    14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKE-YE 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  891 SVLFDtntsLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLlnaaRAAESDFNQKIANLQAC 970
Cdd:COG1579    93 ALQKE----IESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAEL----DEELAELEAELEELEAE 164

                         170
                  ....*....|....*
gi 665394924  971 AEEAAKRHGEEILQL 985
Cdd:COG1579   165 REELAAKIPPELLAL 179
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1481-1688 4.06e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 41.74  E-value: 4.06e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1481 LMHQVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEEKLKHRND 1560
Cdd:COG3883     7 AAPTPAFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERRE 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1561 EcqmLRERLAQTEMQ----------------------LAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVEGRA 1618
Cdd:COG3883    87 E---LGERARALYRSggsvsyldvllgsesfsdfldrLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALK 163

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1619 SKLELQRVAMEGDLTRLQMALQEKDCSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSE 1688
Cdd:COG3883   164 AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAA 233
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1484-1764 4.67e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.43  E-value: 4.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1484 QVAQLEREKDDYKSQLGAAKKQLQDAADQQLRCDAKLGKLQAMLRNLQEEKSNLETDRKMKISAIQALEEKLKHRNDECQ 1563
Cdd:COG4372    32 QLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAE 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1564 MLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSKLDNEKRQLQEELAKVEGRASKLELQRVAMEGDLTRLQMALQEKD 1643
Cdd:COG4372   112 ELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKE 191

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1644 CSIRQMAERLENQNRALTQLEDRCTALKSTVDQLKERLQKSAVSETQLRGEIKTLQKELSEQGHCSQANEDKLKLVQKSL 1723
Cdd:COG4372   192 ANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEK 271

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 665394924 1724 QTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQ 1764
Cdd:COG4372   272 DTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGA 312
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 218-609 5.26e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.97  E-value: 5.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   218 RKLEEEHQRCEQIVAQNSALRQQLEESNRTNEALTNDLQKLTNDWASLRDELLIKEDEFKEEEQafkdyynsEHNRLLKM 297
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEA--------EVEQLEER 748

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   298 WREvvavkrsfkemqtaMKAEVAKMGQEINCVGKDINGSnatvafavQQAKRAADDELKQSQRSNDELQNQLATLKVQYE 377
Cdd:TIGR02168  749 IAQ--------------LSKELTELEAEIEELEERLEEA--------EEELAEAEAEIEELEAQIEQLKEELKALREALD 806

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   378 SARHEIMERDQRLLELMNQLKKLEDRcaqAESQAALASRYSDEIERLNNSMrEIAQAVVQDAENADREADAEVTggvmqh 457
Cdd:TIGR02168  807 ELRAELTLLNEEAANLRERLESLERR---IAATERRLEDLEEQIEELSEDI-ESLAAEIEELEELIEELESELE------ 876

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   458 mHLTRDAASVVGGAGGAGSTAGGGGKSPRRNSTRASQAFAEgtISAVQAALHKYQLALHDMQVKFQNTSETLRTT-KAQL 536
Cdd:TIGR02168  877 -ALLNERASLEEALALLRSELEELSEELRELESKRSELRRE--LEELREKLAQLELRLEGLEVRIDNLQERLSEEySLTL 953

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   537 ETSEGTKQLLTTKMQQLTEKLDSSNSKLSEL-------LQERESLQRGLDDIRVQKqqsemgrADINSAFENLSSDYEKM 609
Cdd:TIGR02168  954 EEAEALENKIEDDEEEARRRLKRLENKIKELgpvnlaaIEEYEELKERYDFLTAQK-------EDLTEAKETLEEAIEEI 1026
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1309-1793 5.47e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 42.13  E-value: 5.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1309 KQLSDLEANLCATRQELGRARCQNNQEEHRFHAREQELAQRLEEgrgrekrLEDQkhnLEVCLADATQQIQELKARLGGA 1388
Cdd:pfam12128  251 NTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRT-------LDDQ---WKEKRDELNGELSAADAAVAKD 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1389 EGRIRALDEQlscvelHKRDTEQKLSSVVHTLRRIAGIQVDGS-VNLSHRLLSPSRRfSPSRSCGDYDNRSTSQCPDGPI 1467
Cdd:pfam12128  321 RSELEALEDQ------HGAFLDADIETAAADQEQLPSWQSELEnLEERLKALTGKHQ-DVTAKYNRRRSKIKEQNNRDIA 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1468 DVDPDLVR-KGVRNLMHQVAQ--LEREKDDYKSQLGAAKKQLQDaadQQLRCDAKLGKLQAMLRNLQEEkSNLETDRKMK 1544
Cdd:pfam12128  394 GIKDKLAKiREARDRQLAVAEddLQALESELREQLEAGKLEFNE---EEYRLKSRLGELKLRLNQATAT-PELLLQLENF 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1545 ISAIQALEEKLKHRNDECQMLRERLAQTEMQLAATSEENGQNEERLEKSRQQCSK---------------LDNEKRQLQE 1609
Cdd:pfam12128  470 DERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDElelqlfpqagtllhfLRKEAPDWEQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1610 ELAKVEGRAsklELQRVAMEGDLTRLQMALQEKDCSIRQMAERLE-NQNRALTQ-LEDRCTALKSTVDQLKERLQKSAVS 1687
Cdd:pfam12128  550 SIGKVISPE---LLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDvPEWAASEEeLRERLDKAEEALQSAREKQAAAEEQ 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1688 ETQLRGEIKTLQKELSEQGHCSQANEDKLklvQKSLQTAENEKRILTERLDSAQTNLNELRRSQQAQLDGNQRLQEQVTD 1767
Cdd:pfam12128  627 LVQANGELEKASREETFARTALKNARLDL---RRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLE 703

                          490       500
                   ....*....|....*....|....*.
gi 665394924  1768 lEVQRSALESQLRIAKWNQESGGDKD 1793
Cdd:pfam12128  704 -EQKEQKREARTEKQAYWQVVEGALD 728
HCR pfam07111
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ...
 731-1266 5.48e-03

Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.


Pssm-ID: 284517 [Multi-domain]  Cd Length: 749  Bit Score: 41.66  E-value: 5.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   731 ELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKElaildkarlELETDNLSAGEKLKCLQLEKEKILQDLACVTRDRG 810
Cdd:pfam07111  116 EAEGLRAALAGAEMVRKNLEEGSQRELEEIQRLHQE---------QLSSLTQAHEEALSSLTSKAEGLEKSLNSLETKRA 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   811 DIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVvidlHEKDTHRLNELLAALRSEKESLE 890
Cdd:pfam07111  187 GEAKQLAEAQKEAELLRKQLSKTQEELEAQVTLVESLRKYVGEQVPPEVHSQT----WELERQELLDTMQHLQEDRADLQ 262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   891 SVLFDTNTSLEATEERRSQLERDLQEALVREESLKNHVARLQKELEQCQRKAQETKTQLLNAARAAESDFNQKIANLQAC 970
Cdd:pfam07111  263 ATVELLQVRVQSLTHMLALQEEELTRKIQPSDSLEPEFPKKCRSLLNRWREKVFALMVQLKAQDLEHRDSVKQLRGQVAE 342

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   971 AEEAAKRHGEEILQLRNALEKRMQQALQALQTAKDDEIE---------KLQERLATLQAHLESLVQQHEEALIRAES--- 1038
Cdd:pfam07111  343 LQEQVTSQSQEQAILQRALQDKAAEVEVERMSAKGLQMElsraqearrRQQQQTASAEEQLKFVVNAMSSTQIWLETtmt 422

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1039 --EKQQALLIAHRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECIR 1116
Cdd:pfam07111  423 rvEQAVARIPSLSNRLSYAVRKVHTIKGLMARKVALAQLRQESCPPPPPAPPVDADLSLELEQLREERNRLDAELQLSAH 502

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  1117 KQELQLSSLRE----ERESLCRVSEELKMEIRLKEDRMESTNNELQDALRKSKEGEGFIDSLRKELTDCRRQLADSNIER 1192
Cdd:pfam07111  503 LIQQEVGRAREqgeaERQQLSEVAQQLEQELQRAQESLASVGQQLEVARQGQQESTEEAASLRQELTQQQEIYGQALQEK 582

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 665394924  1193 --DKYSGSNKELRDHVKRVESAKREQARAIEEALQKISNLEDTKNSLENERTRLSTILKETENHFTKTTQDLNATK 1266
Cdd:pfam07111  583 vaEVETRLREQLSDTKRRLNEARREQAKAVVSLRQIQHRATQEKERNQELRRLQDEARKEEGQRLARRVQELERDK 658
antiphage_ZorA_2 NF033915
anti-phage ZorAB system protein ZorA; Proteins of this subfamily are putative H+ channel ...
 962-1131 6.04e-03

anti-phage ZorAB system protein ZorA; Proteins of this subfamily are putative H+ channel proteins, but it has been reported that they are also involved in anti-phage defense.


Pssm-ID: 411476 [Multi-domain]  Cd Length: 383  Bit Score: 41.29  E-value: 6.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  962 QKIANLQACAEEA----AKRHGEEILQLRNALEKRMQQAL-QALQTAKDDEIEKL-QERLATLQAHLESLVQQHEEALIR 1035
Cdd:NF033915  209 VHIAEYSKESKEAlqelHERIGDRLQESLNGMSEAMQTALtDALNNIMAPAIQTLvSTTSQQSTQVLESLVGNFMDGMTS 288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1036 AESEKQQALliahrdKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEHKIKLEECI 1115
Cdd:NF033915  289 AGREQGLQM------QQAAADVNAAVSGMSERLNQLFNSLSEQQGRQMERAQQQSSTFETQLQRLSGSANERQAQLEQRF 362

                         170
                  ....*....|....*.
gi 665394924 1116 RKQELQLSSLREERES 1131
Cdd:NF033915  363 EELMSGLTEQLQTQLG 378
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 498-916 6.22e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 41.63  E-value: 6.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   498 EGTISAVQAALHKYQLALHDMQVKFQNTSETLRTTKAQLETSEGTKQLLTTKMQ-------------------------- 551
Cdd:pfam05483  334 EAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQkksseleemtkfknnkeveleelkki 413

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   552 ---------------QLTEKLDSSNSKLSELLQEREslqRGLDDIRVQKQQSEMGRADINSAFENLSSDYEKMQLNCGKL 616
Cdd:pfam05483  414 laedeklldekkqfeKIAEELKGKEQELIFLLQARE---KEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIEL 490

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   617 QKRIDSME-EDKKAVELEIQRILKDKNITE--LNLRSEEDRSSR----LREETISLREELNRVslnRDLLEQQRIESDNL 689
Cdd:pfam05483  491 TAHCDKLLlENKELTQEASDMTLELKKHQEdiINCKKQEERMLKqienLEEKEMNLRDELESV---REEFIQKGDEVKCK 567

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   690 INLLEKQKSDLEYDLDKlllekcdlQEKHEKLSNNSCST-SDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKEla 768
Cdd:pfam05483  568 LDKSEENARSIEYEVLK--------KEKQMKILENKCNNlKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIK-- 637

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924   769 iLDKARLELETDNLSAGEKLKCLQLEKEkilqdlacvtrDRGDIHNQLTAMCRKKEALNEELMRTRQRLE-----QTTET 843
Cdd:pfam05483  638 -VNKLELELASAKQKFEEIIDNYQKEIE-----------DKKISEEKLLEEVEKAKAIADEAVKLQKEIDkrcqhKIAEM 705

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 665394924   844 NSRLNRNLEEMVKDVEEKQVVIDLHEKDTHRLNELLAALRSEKESLESVLFDTNTSLEATEERRSQLERDLQE 916
Cdd:pfam05483  706 VALMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKE 778
PRK01156 PRK01156
chromosome segregation protein; Provisional
 549-1178 6.24e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 41.81  E-value: 6.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  549 KMQQLTEKLDSSNSKLSELLQERESLQRGLDdirVQKQQSEMGRADInSAFENLSSDYEKMQLNCGKLQKRIDSMEEDKK 628
Cdd:PRK01156  139 EMDSLISGDPAQRKKILDEILEINSLERNYD---KLKDVIDMLRAEI-SNIDYLEEKLKSSNLELENIKKQIADDEKSHS 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  629 AVELEIQRILKDKNITElnlrseedrssrlrEETISLREELNRVSLNRDllEQQRIESDnlinlLEKQKSDLEYDLDKLL 708
Cdd:PRK01156  215 ITLKEIERLSIEYNNAM--------------DDYNNLKSALNELSSLED--MKNRYESE-----IKTAESDLSMELEKNN 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  709 lEKCDLQEKHEKLSNNSCSTSDELKSVQNCLQEAQEERKKLRIQSVDQCNEIGELKKELAILDKARLELETdnlsagekl 788
Cdd:PRK01156  274 -YYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAIIKKLSVLQKDYNDYIK--------- 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  789 kcLQLEKEKILQDLACVTRDRGDIHNQLTAMCRKKEALNEELMRTRQRLEQTTETNSRLNRNLEEMVKDVEEKQVVIDLH 868
Cdd:PRK01156  344 --KKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDI 421

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  869 EKDTHRLNELLAALRSEKESLE---------SVLFDTNTSL---------EATEERRSQLERDLQEALVREESLKNHVAR 930
Cdd:PRK01156  422 SSKVSSLNQRIRALRENLDELSrnmemlngqSVCPVCGTTLgeeksnhiiNHYNEKKSRLEEKIREIEIEVKDIDEKIVD 501

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  931 LQKELEQCQRK---AQETKTQLLNAARAAESDFNQKIANLqACAEEAAKRHGEEILQLR-NALEKRMQQALQALQTAKDD 1006
Cdd:PRK01156  502 LKKRKEYLESEeinKSINEYNKIESARADLEDIKIKINEL-KDKHDKYEEIKNRYKSLKlEDLDSKRTSWLNALAVISLI 580

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1007 EIEKLQERLATLQAHLESLVQQHEEALIRAESEKQQALLIAHRDKQAV------AERLEAVSRDLKTEQESLDRSRREAN 1080
Cdd:PRK01156  581 DIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEAnnlnnkYNEIQENKILIEKLRGKIDNYKKQIA 660

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1081 ARDEKQRaaiaQLKDEMVQMRTKEEEHKiKLEECIRKQELQLSSLREERESLCRVSEELKMEIRLKEDRMEStnnelqda 1160
Cdd:PRK01156  661 EIDSIIP----DLKEITSRINDIEDNLK-KSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLES-------- 727

                         650
                  ....*....|....*...
gi 665394924 1161 LRKSKEGEGFIDSLRKEL 1178
Cdd:PRK01156  728 MKKIKKAIGDLKRLREAF 745
mukB PRK04863
chromosome partition protein MukB;
741-1125 7.25e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.48  E-value: 7.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  741 EAQEERKKLRIQSVDQCNEIGELKKELAILDKARLELETDNLSAGEKLKCLQ---LEKEKILQDLAcvtrDRGDIHNQLT 817
Cdd:PRK04863  290 ELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQtalRQQEKIERYQA----DLEELEERLE 365

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  818 AMCRKKEALNEELMRTRQRLEQTTETNSRLNRNL-----------------EEMVKDVEEKQVVIDLHEKDTHRLNELLA 880
Cdd:PRK04863  366 EQNEVVEEADEQQEENEARAEAAEEEVDELKSQLadyqqaldvqqtraiqyQQAVQALERAKQLCGLPDLTADNAEDWLE 445

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  881 ALRSEKESLESVLFDTNTSLEATEERRSQLERDLQeaLVReeSLKNHVARlqkelEQCQRKAQETKTQLLnaaraaesdf 960
Cdd:PRK04863  446 EFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQ--LVR--KIAGEVSR-----SEAWDVARELLRRLR---------- 506

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  961 NQKIANLQACAEEAAKRHGEEILQLRNALEKRMQQALQALQTAKDDEIEkLQERLATLQAHLESLVQQHEEALIRAESEK 1040
Cdd:PRK04863  507 EQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDE-LEQLQEELEARLESLSESVSEARERRMALR 585

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924 1041 QQAlliahRDKQAVAERLEAVSRDLKTEQESLDRSRREANARDEKQRAAIAQLKDEMVQMRTKEEEhKIKLEECIRKQEL 1120
Cdd:PRK04863  586 QQL-----EQLQARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQLLERERELTVE-RDELAARKQALDE 659


                  ....*
gi 665394924 1121 QLSSL 1125
Cdd:PRK04863  660 EIERL 664
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 538-753 8.38e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.97  E-value: 8.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  538 TSEGTKQLLTTKMQQLTEKLDSSNSKLSELLQERESLQRGLDDIRVQKQQSEMGRADINSAFENLSSDYEKMQlncGKLQ 617
Cdd:COG3883    13 FADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERR---EELG 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  618 KRIDSMEEDKKAVELeIQRILKDKNITELNlrseeDRSSRLREETISLREELNRVSLNRDLLEQQRIESDNLINLLEKQK 697
Cdd:COG3883    90 ERARALYRSGGSVSY-LDVLLGSESFSDFL-----DRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALK 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 665394924  698 SDLEYDLDKLLLEKCDLQEKHEKLSNNSCSTSDELKSVQNCLQEAQEERKKLRIQS 753
Cdd:COG3883   164 AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAA 219
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 558-777 9.40e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 41.07  E-value: 9.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  558 DSSNSKLSELLQERESLQRGLDDIR-----VQKQQSEMGRADINSAfENLSSDYEKmqlNCGKLQKRIDSMEEDKKAVEL 632
Cdd:PRK05771   39 ELSNERLRKLRSLLTKLSEALDKLRsylpkLNPLREEKKKVSVKSL-EELIKDVEE---ELEKIEKEIKELEEEISELEN 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 665394924  633 EIQRILKDKNITEL--NLRSEEdrsSRLREETiSLREELNRVSLNRDLLEQQRIESDNLINLLEKQ---------KSDLE 701
Cdd:PRK05771  115 EIKELEQEIERLEPwgNFDLDL---SLLLGFK-YVSVFVGTVPEDKLEELKLESDVENVEYISTDKgyvyvvvvvLKELS 190

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 665394924  702 YDLDKlLLEKCDLQEKHeklSNNSCSTSDELKSVQNCLQEAQEERKKLRiqsvdqcNEIGELKKELAILDKARLEL 777
Cdd:PRK05771  191 DEVEE-ELKKLGFERLE---LEEEGTPSELIREIKEELEEIEKERESLL-------EELKELAKKYLEELLALYEY 255
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH