|
Name |
Accession |
Description |
Interval |
E-value |
| MFS_NaGLT1_MFSD4B |
cd17454 |
Sodium-dependent glucose transporter 1, also called Major facilitator superfamily ... |
45-452 |
0e+00 |
|
Sodium-dependent glucose transporter 1, also called Major facilitator superfamily domain-containing protein 4B; Sodium-dependent glucose transporter 1 (NaGLT1) is also called major facilitator superfamily domain-containing protein 4B (MFSD4B). NaGLT1 is a primary fructose transporter in rat renal brush-border membranes. It also facilitates sodium-independent urea uptake in assays performed on Xenopus oocytes. NaGLT1/MFSD4B belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 341012 Cd Length: 369 Bit Score: 571.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 45 VLNAAFLGMGVSAAVLGPTFPDLARNVNRNISSLSEIFVGRALGYLGGSVVGGVLFDCMNHFLLLGLSHLLTAAGLYLTP 124
Cdd:cd17454 1 ALCASFLGLGMSIAVLGPTFQDLATNVNKNISNISYIFVGRSLGYLGGSVLGGILFDCMNHHLLLGFSMLITAAGLFAIP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 125 FCKTAALLTAMMSITGVSFGVLDTGGNVLILDLWGDKGAPHIQALHFSFALGAFLAPLLAKLAWgttasaqnhtepqldr 204
Cdd:cd17454 81 WCKKALLLTALMSLIGVSMGVLDTGGNVLILNTWGDQAGPHMQALHFSFALGAFVAPILAKLAF---------------- 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 205 salnrsfeaasdsvlavpddmnlLWAYASIGTYVLVLSVFLFAPFFKKRSKQKKSAASAQGARRAKYHRALLCLLFLFFF 284
Cdd:cd17454 145 -----------------------LWAYIVIGTYVLLVSLFFFILYSKSSSNREKSKASAQKTRFAKYHNALIILLFLFFF 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 285 FYVGAEVTYGSYVFSFATTHVGMEESEAAGLNSIFWGTFAACRGLAIFFATLLQPGTMMVLCNIGSLASSFFLVLFDKSP 364
Cdd:cd17454 202 FYVGAEVTYGSYIFTYAKTYVHMEESEAAGLNSLFWGTFAACRGLAIFFAACLYPGTMILLSLIGSTVSSLFLVLFSKNP 281
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 365 LCLWIASSVYGASMAATFPSGISWIEQYTTLTGKSAAFILVGAALGLMATPALSGILQGHYPDLPVILYMCLGSAVLTTV 444
Cdd:cd17454 282 ISLWVGTAVYGASMATTFPSGISWIEQYTTITGKSAALFVVGAALGEMVIPAVVGYLQGHVPDYPVLMYTALGTSTMTAI 361
|
....*...
gi 28570190 445 LFPVMYKV 452
Cdd:cd17454 362 LFPVMYKL 369
|
|
| FucP |
COG0738 |
Fucose permease [Carbohydrate transport and metabolism]; |
39-452 |
4.47e-28 |
|
Fucose permease [Carbohydrate transport and metabolism];
Pssm-ID: 440501 [Multi-domain] Cd Length: 391 Bit Score: 115.34 E-value: 4.47e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 39 RWFTTVVLNAAFLGMGVSAAVLGPTFPDLARNVNRNISSLSEIFVGRALGYLGGSVVGGVLFDCMNHFLLLGLSHLLTAA 118
Cdd:COG0738 6 YRRALIAIYLLFFLWGFATALWGPLIPALKDAFGLSDAQAGLLLFAFFLGYLLASLPAGRLIDRFGYKRGLLLGLLLMAL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 119 GLYLTPFCKTAALLTAMMSITGVSFGVLDTGGNVLILDLWGDKGAPHIQALHFSFALGAFLAPLLAKLAwgttasaqnht 198
Cdd:COG0738 86 GLLLFALAPSYPLLLLALFLLGLGLGLLDVAANPYVAALGPETAASRLNLLHAFFSLGALLGPLLGGLL----------- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 199 epqldrsalnrsfeaasdsvLAVPDDMNLLWAYASIGTYVLVLSVFLFAPFFKKRSKQKKSAASAQGARRAKYHRALLCL 278
Cdd:COG0738 155 --------------------ILLGLSLSWHLPYLILAVLLLLLALLFLRSKLPEIEEEEEEAAGSAASLKSLLKNPRLLL 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 279 LFLFFFFYVGAEVTYGSYVFSFATTHVGMEESEAAGLNSIFWGTFAACRGLAIFFATLLQPGTMMVLCNIGSLASSFFLV 358
Cdd:COG0738 215 GGLAIFLYVGAEGAIGDWLPLYLKDVLGLSEATAALGLSLFWGGMTIGRFLGGFLLKRFGPVRLLRLSALLAAVGLLLAL 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 359 LFDKSPLCLWIASSVyGASMAATFPSGISW-IEQYTTLTGKSAAFILVGAALGLMATPALSGILQGHYpDLPVILYMCLG 437
Cdd:COG0738 295 LAPGPWLALIGLALV-GLGLSLMFPTIFSLaLDGLGKRTAAAVSAVLIMGIVGGAIGPPLIGFLADAF-GLRAAFLVPLV 372
|
410
....*....|....*
gi 28570190 438 SAVLTTVLFPVMYKV 452
Cdd:COG0738 373 CYLLILLLALALKRK 387
|
|
| PRK03699 |
PRK03699 |
putative transporter; Provisional |
53-425 |
2.90e-04 |
|
putative transporter; Provisional
Pssm-ID: 235151 [Multi-domain] Cd Length: 394 Bit Score: 42.99 E-value: 2.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 53 MGVSAAVLGPTFPDLARNVNRNISSLSEIFVGRALGYLGGSVVGGVLfdcMNHF------LLLGLSHLLTAAGLYLTPfc 126
Cdd:PRK03699 19 TGALVIVTGMVMGPIAEYFNLPVSSMSNTFTFLNAGILISIFLNAWL---MEIIplkrqlIFGFALMILAVAGLMFSH-- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 127 kTAALLTAMMSITGVSFGVLDTGGNVLILDLWGDKgaphIQALH-----FSFALGAFLAPLLAklAWgttasaqnhtepq 201
Cdd:PRK03699 94 -SLALFSIAMFVLGVVSGITMSIGTFLITHVYEGK----QRGSRllftdSFFSMAGMIFPIIA--AY------------- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 202 ldrsALNRSFEaasdsvlavpddmnLLWAYASIG-TYVLVLSVFLFAPFfkkrSKQKKSAASAQGARRAKYHRALLCLLF 280
Cdd:PRK03699 154 ----LLARSIE--------------WYWVYACIGlVYVAIFILTLFSEF----PALGKHAPKADKPVAKEKWGIGVLFLA 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 281 LFFFFYVGAEVTYGSYVFSFATTHVGMEESEAAGLNSIFWGtfAACRGLAIFFATL----LQpgTMMVLCNIGSLASSFF 356
Cdd:PRK03699 212 IAALLYILAQLTFISWVPEYAQKKFGMSLEDAGNLVSNFWM--AYMVGMWIFSFIVrffdLQ--RILTVLAGLALVLMYL 287
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 357 LVLFDKSPLCLWIASSvYGASMAATFPSGISWIEQYTTLTG-KSAAFILVGAALGLMATPALSGILQGHY 425
Cdd:PRK03699 288 FVNTDDPSHLLYAILG-LGFFSSAIYTTIITLGSQQTKVASpKLVNFILTCGTIGTMLTFVVTSPIVAHF 356
|
|
| MFS_1 |
pfam07690 |
Major Facilitator Superfamily; |
49-415 |
6.53e-04 |
|
Major Facilitator Superfamily;
Pssm-ID: 429598 [Multi-domain] Cd Length: 344 Bit Score: 42.02 E-value: 6.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 49 AFLGMGVSAAVLGPTFP-DLARNVNRNISSLSEIFVGRALGYLGGSVVGGVLFDCMNHFLLLGLSHLLTAAGLYLTPFCK 127
Cdd:pfam07690 4 AAFLAALGRSLLGPALPlLLAEDLGISPTEIGLLLTLFSLGYALAQPLAGRLSDRFGRRRVLLIGLLLFALGLLLLLFAS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 128 TAALLTAMMSITGVSFGVLDTGGNVLILDLWGDKGAPHIQAL-HFSFALGAFLAPLLAklawgttasaqnhtepqldrsa 206
Cdd:pfam07690 84 SLWLLLVLRVLQGLGAGALFPAALALIADWFPPEERGRALGLvSAGFGLGAALGPLLG---------------------- 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 207 lnrsfeaasdSVLAVPDDMNLLWAYASIGTYVLVLSVFLFAPFFKKRSKQKKSAASAQGARRAKYHRALLCLLFLFFFFY 286
Cdd:pfam07690 142 ----------GLLASLFGWRAAFLILAILSLLAAVLLLLPRPPPESKRPKPAEEARLSLIVAWKALLRDPVLWLLLALLL 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 287 VGAEVTYGSYVFSFATTHVGMEESEAAGLNSIFWGTFAACRGLAIFFATLLQPGTMMVLCNIGSLASSFFLVL--FDKSP 364
Cdd:pfam07690 212 FGFAFFGLLTYLPLYQEVLGLSALLAGLLLGLGGLLGAIGRLLLGRLSDRLGRRRRLLLALLLLILAALGLLLlsLTLSS 291
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 28570190 365 LCLWIASSVYGASMAATFPSGISWIEQY--TTLTGKSAAFILVGAALGLMATP 415
Cdd:pfam07690 292 LWLLLALLLLGFGFGLVFPALNALVSDLapKEERGTASGLYNTAGSLGGALGP 344
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MFS_NaGLT1_MFSD4B |
cd17454 |
Sodium-dependent glucose transporter 1, also called Major facilitator superfamily ... |
45-452 |
0e+00 |
|
Sodium-dependent glucose transporter 1, also called Major facilitator superfamily domain-containing protein 4B; Sodium-dependent glucose transporter 1 (NaGLT1) is also called major facilitator superfamily domain-containing protein 4B (MFSD4B). NaGLT1 is a primary fructose transporter in rat renal brush-border membranes. It also facilitates sodium-independent urea uptake in assays performed on Xenopus oocytes. NaGLT1/MFSD4B belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 341012 Cd Length: 369 Bit Score: 571.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 45 VLNAAFLGMGVSAAVLGPTFPDLARNVNRNISSLSEIFVGRALGYLGGSVVGGVLFDCMNHFLLLGLSHLLTAAGLYLTP 124
Cdd:cd17454 1 ALCASFLGLGMSIAVLGPTFQDLATNVNKNISNISYIFVGRSLGYLGGSVLGGILFDCMNHHLLLGFSMLITAAGLFAIP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 125 FCKTAALLTAMMSITGVSFGVLDTGGNVLILDLWGDKGAPHIQALHFSFALGAFLAPLLAKLAWgttasaqnhtepqldr 204
Cdd:cd17454 81 WCKKALLLTALMSLIGVSMGVLDTGGNVLILNTWGDQAGPHMQALHFSFALGAFVAPILAKLAF---------------- 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 205 salnrsfeaasdsvlavpddmnlLWAYASIGTYVLVLSVFLFAPFFKKRSKQKKSAASAQGARRAKYHRALLCLLFLFFF 284
Cdd:cd17454 145 -----------------------LWAYIVIGTYVLLVSLFFFILYSKSSSNREKSKASAQKTRFAKYHNALIILLFLFFF 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 285 FYVGAEVTYGSYVFSFATTHVGMEESEAAGLNSIFWGTFAACRGLAIFFATLLQPGTMMVLCNIGSLASSFFLVLFDKSP 364
Cdd:cd17454 202 FYVGAEVTYGSYIFTYAKTYVHMEESEAAGLNSLFWGTFAACRGLAIFFAACLYPGTMILLSLIGSTVSSLFLVLFSKNP 281
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 365 LCLWIASSVYGASMAATFPSGISWIEQYTTLTGKSAAFILVGAALGLMATPALSGILQGHYPDLPVILYMCLGSAVLTTV 444
Cdd:cd17454 282 ISLWVGTAVYGASMATTFPSGISWIEQYTTITGKSAALFVVGAALGEMVIPAVVGYLQGHVPDYPVLMYTALGTSTMTAI 361
|
....*...
gi 28570190 445 LFPVMYKV 452
Cdd:cd17454 362 LFPVMYKL 369
|
|
| MFS_MFSD4 |
cd17395 |
Major facilitator superfamily domain-containing protein 4; The Major facilitator superfamily ... |
45-452 |
1.67e-157 |
|
Major facilitator superfamily domain-containing protein 4; The Major facilitator superfamily domain-containing protein 4 (MFSD4) subfamily consists of two vertebrate members: MFSD4A and MFSD4B. The function of MFSD4A is unknown. MFSD4B is more commonly know as sodium-dependent glucose transporter 1 (NaGLT1), a primary fructose transporter in rat renal brush-border membranes that also facilitates sodium-independent urea uptake. The MFSD4 subfamily belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340953 [Multi-domain] Cd Length: 367 Bit Score: 451.59 E-value: 1.67e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 45 VLNAAFLGMGVSAAVLGPTFPDLARNVNRNISSLSEIFVGRALGYLGGSVVGGVLFDCMNHFLLLGLSHLLTAAGLYLTP 124
Cdd:cd17395 1 TYWSVFFSFGLSIAFLGPTLLDLACNTNSSLPQISWVFFSRQLGYLLGSALGGVFKRTLNSLWALFTSSLLIALVLAVIP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 125 FCKTAALLTAMMSITGVSFGVLDTGGNVLILDLWGDKGAPHIQALHFSFALGAFLAPLLAKLAwgttasaqnhtepqldr 204
Cdd:cd17395 81 FCKDVKVLASVMAIAGLAMGCLDTGANMQIVRMWQKDSAPFLQVLHFSFGFGAFLAPLIADPF----------------- 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 205 salnrsfeaasdsvlavpddmnLLWAYASIGTYVLVLSVFLFAPFFKKRSKQKKSAA-SAQGARRAKYHRALLCLLFLFF 283
Cdd:cd17395 144 ----------------------LSYAYWIMALINLPVPMAVLMLLSKERLLTCCSQRrRKNLRRAPYSFFAIHITGALFL 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 284 FFYVGAEVTYGSYVFSFATTHVGMEESEAAGLNSIFWGTFAACRGLAIFFATLLQPGTMMVLCNIGSLASSFFLVLFDKS 363
Cdd:cd17395 202 FMYVGLEGAYGAFVYSYAVEKPGVGHKVAAYLPSLFWGTFTLGRLLSIPISSRMKPATMVVLNVVGVVVTSLVLLLFSKS 281
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 364 PLCLWIASSVYGASMAATFPSGISWIEQYTTLTGKSAAFILVGAALGLMATPALSGILQghyPDLPVILYMCLGSAVLTT 443
Cdd:cd17395 282 VVFLWIGTASLGLFLASTFPSMLSYTEDSLQYTGCSTTVLVTGAGLGEMVLPMLVGSIQ---PFQAQGSYSFLVCGVLFG 358
|
....*....
gi 28570190 444 VLFPVMYKV 452
Cdd:cd17395 359 CLAFTFYIL 367
|
|
| MFS_FucP_MFSD4_like |
cd17333 |
Bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein ... |
49-445 |
3.02e-29 |
|
Bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4, and similar proteins; This family is composed of bacterial L-fucose permease (FucP), eukaryotic Major facilitator superfamily domain-containing protein 4 (MFSD4) proteins, and similar proteins. L-fucose permease facilitates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell; it can also transport L-galactose and D-arabinose. The MFSD4 subfamily consists of two vertebrate members: MFSD4A and MFSD4B. The function of MFSD4A is unknown. MFSD4B is more commonly know as Sodium-dependent glucose transporter 1 (NaGLT1), a primary fructose transporter in rat renal brush-border membranes that also facilitates sodium-independent urea uptake. The FucP/MFSD4 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340891 [Multi-domain] Cd Length: 372 Bit Score: 118.19 E-value: 3.02e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 49 AFLGMGVSAAVLGPTFPDLARNVNRNISSLSEIFVGRALGYLGGSVVGGVLFDCMNHFLLLGLSHLLTAAGLYLTPFCKT 128
Cdd:cd17333 4 SFFSNGLTDALLGILGPSLEEAFNLNVADVSVIFSSQNAGYLIGSLLAGFLMKRLGRRRTLILGLLLISLALALIFATPS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 129 AALLTAMMSITGVSFGVLDTGGNVLILDLWGDKGAPHIQALHFSFALGAFLAPLLAKLAWGTTASAQnhtepqldrsaln 208
Cdd:cd17333 84 IYLFVVLMFLAGLGAGILDTGANTFVGALFEESSATRLNVLHGFFGLGALIGPLIATSLLTSELSWS------------- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 209 rsfeaasdsvlavpddmnllWAYASIGTYVLVLSVFLFAPFFKKR--SKQKKSAASAQGARRAKYHR-ALLCLLFLFFFF 285
Cdd:cd17333 151 --------------------WAYLIIGLIYLLLAILILLTLFPELpsARNPQQSVGAFSASASRLLRnPSIILGALALFL 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 286 YVGAEVTYGSYVFSFATTHVGMEESEAAGLNSIFWGTFAACRGLAIFFATLLQPGTMMVLCNIGSLAsSFFLVLFDKSPL 365
Cdd:cd17333 211 YVGAETAFSSWVPSYLVEKKHVSDGLAGYLLSGFWVGITIGRLLGGPISRRIKPHTLLVLSGSGALL-GLLILLLAPTLV 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 366 CLWIASSVYGASMAATFPSGISW-IEQYTTLTGKSAAFILVGAALGLMATPALSGILqGHYPDLPVILYMCLGSAVLTTV 444
Cdd:cd17333 290 VGLVATALLGLFMAALFPTILSLgISNLPYAKGKGTSVLLAAGSIGGAIIPFIMGFI-AEAVGIQTAMLLITILYAIIFV 368
|
.
gi 28570190 445 L 445
Cdd:cd17333 369 L 369
|
|
| FucP |
COG0738 |
Fucose permease [Carbohydrate transport and metabolism]; |
39-452 |
4.47e-28 |
|
Fucose permease [Carbohydrate transport and metabolism];
Pssm-ID: 440501 [Multi-domain] Cd Length: 391 Bit Score: 115.34 E-value: 4.47e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 39 RWFTTVVLNAAFLGMGVSAAVLGPTFPDLARNVNRNISSLSEIFVGRALGYLGGSVVGGVLFDCMNHFLLLGLSHLLTAA 118
Cdd:COG0738 6 YRRALIAIYLLFFLWGFATALWGPLIPALKDAFGLSDAQAGLLLFAFFLGYLLASLPAGRLIDRFGYKRGLLLGLLLMAL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 119 GLYLTPFCKTAALLTAMMSITGVSFGVLDTGGNVLILDLWGDKGAPHIQALHFSFALGAFLAPLLAKLAwgttasaqnht 198
Cdd:COG0738 86 GLLLFALAPSYPLLLLALFLLGLGLGLLDVAANPYVAALGPETAASRLNLLHAFFSLGALLGPLLGGLL----------- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 199 epqldrsalnrsfeaasdsvLAVPDDMNLLWAYASIGTYVLVLSVFLFAPFFKKRSKQKKSAASAQGARRAKYHRALLCL 278
Cdd:COG0738 155 --------------------ILLGLSLSWHLPYLILAVLLLLLALLFLRSKLPEIEEEEEEAAGSAASLKSLLKNPRLLL 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 279 LFLFFFFYVGAEVTYGSYVFSFATTHVGMEESEAAGLNSIFWGTFAACRGLAIFFATLLQPGTMMVLCNIGSLASSFFLV 358
Cdd:COG0738 215 GGLAIFLYVGAEGAIGDWLPLYLKDVLGLSEATAALGLSLFWGGMTIGRFLGGFLLKRFGPVRLLRLSALLAAVGLLLAL 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 359 LFDKSPLCLWIASSVyGASMAATFPSGISW-IEQYTTLTGKSAAFILVGAALGLMATPALSGILQGHYpDLPVILYMCLG 437
Cdd:COG0738 295 LAPGPWLALIGLALV-GLGLSLMFPTIFSLaLDGLGKRTAAAVSAVLIMGIVGGAIGPPLIGFLADAF-GLRAAFLVPLV 372
|
410
....*....|....*
gi 28570190 438 SAVLTTVLFPVMYKV 452
Cdd:COG0738 373 CYLLILLLALALKRK 387
|
|
| MFS_MFSD4A |
cd17453 |
Major facilitator superfamily domain-containing protein 4A; Major facilitator superfamily ... |
50-446 |
1.08e-16 |
|
Major facilitator superfamily domain-containing protein 4A; Major facilitator superfamily domain-containing protein 4A (MFSD4A) belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 341011 Cd Length: 415 Bit Score: 81.77 E-value: 1.08e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 50 FLGMGVSAAVLGPTFPDLARNVNRNISSLSEIFVGRALGYLGGSVVGGVLFDCMNHFLLLGLSHLLTAAGLY-LTPFCKT 128
Cdd:cd17453 8 FFSFGLCIAFLGPTLLDLRCQTQSSLQQITWVFFSQQFCLLLGSTLGGVFKRTLAQSLFALFVSSLAISVVFaIIPFCRN 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 129 AALLTAMMSITGVSFGVLDTGGNVLILDLWGDKGAPHIQALHFSFALGAFLAPLLAklawgttasaqnhtEPQL-DRSAL 207
Cdd:cd17453 88 VGVLAFVMAVAGLAMGCIDTISNMQLVKIYQKDSAVFLQALHFFVGFGALLSPLIA--------------DPFLsDTNCV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 208 NRSFEAASDSVLAVPddmnllwayasIGTYVLVLSVFLFAPFFKKR-------------SKQKKSAASAQGARRAKYHR- 273
Cdd:cd17453 154 SYAFWIMAIINLPVP-----------IAVFVLLYKERMVPCCSDPSrpllsadelameaRPEEKLDESTGKAHTSNGHAd 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 274 ----ALLCLLFLFFFFYVGAEVT--------------YGSYVFSFATTH-VGMEESEAAGLNSIFWGTFAACRGLAIFFA 334
Cdd:cd17453 223 lfscCQSKNFRGAPFSFFAIHVTgalvlfmtdgivgeYSGFVYSYAVEPpLNLPHKVAGYLPSLFWGFITLGRLISIPIS 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 335 TLLQPGTMMVLCNIGSLASSFFLVLFDKSPLCLWIASSVYGASMAATFPSGISWIEQYTTLTGKSAAFILVGAALGLMAT 414
Cdd:cd17453 303 YRMKPATMVFINLVGVIVTFLLLLIFSNSTVFLFVGTASLGLFLSSTFPSMLAYTEDILQYKGCATTVLVTGAGMGEMVL 382
|
410 420 430
....*....|....*....|....*....|....*
gi 28570190 415 PALSGIL---QGHYPDLpvILYMCLGSAVLTTVLF 446
Cdd:cd17453 383 QMLVGSImhsQGSYSFL--VCGMIFGCLAFTFYTF 415
|
|
| MFS |
cd06174 |
Major Facilitator Superfamily; The Major Facilitator Superfamily (MFS) is a large and diverse ... |
49-446 |
7.03e-09 |
|
Major Facilitator Superfamily; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.
Pssm-ID: 349949 [Multi-domain] Cd Length: 378 Bit Score: 57.44 E-value: 7.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 49 AFLGMGVSAAVLGPTFPDLARNVNRNISSLSEIFVGRALGYLGGSVVGGVLFDCMNHFLLLGLSHLLTAAGLYLTPFCKT 128
Cdd:cd06174 4 GFFLTGLARGLISPLLPALLQSFGLSASQLGLLFALFSLGYALLQPLAGLLADRFGRRPVLLLGLLLFALGALLFAFAPS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 129 AALLTAMMSITGVSFGVLDTGGNVLILDLWGDKGAPHIQALHFSF-ALGAFLAPLLAklawgttasaqnhtepqldrsal 207
Cdd:cd06174 84 FWLLLLGRFLLGLGSGLIDPAVLALIADLFPERERGRALGLLQAFgSVGGILGPLLG----------------------- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 208 nrsfeaasdSVLAVPDDMNLLWAYASIGTYVLVLSVFLFAPFFKKRSKQKKSAASAQGARRAK-----YHRALLCLLFLF 282
Cdd:cd06174 141 ---------GILASSLGFGWRAVFLIAAALALLAAILLLLVVPDPPESARAKNEEASSKSVLKllkrvLKNPGLWLLLLA 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 283 FFFYVGAEVTYGSYVFSFATTHVGMEESEAAGLNSIFWGTFAACRGLAIFFATLLQPGTMMVLCNIGSLASSFFLVLFDK 362
Cdd:cd06174 212 IFLVNLAYYSFSTLLPLFLLDLGGLSVAVAGLLLSLFGLAGALGSLLLGLLSDRLIGRKPLLLIGLLLMALGLALLLLAP 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 363 SPLCLWIASSVYGASMAATFPSGISWIEQYTTLTGKSAA--FILVGAALGLMATPALSGILQGHYPDLPVILYMCLGSAV 440
Cdd:cd06174 292 SLLLLLLLLLLLGFGLGGLLPLSFALIAELFPPEIRGTAfgLLNTFGFLGGAIGPLLAGFLLAATFGLTGAFLVLAVLLL 371
|
....*.
gi 28570190 441 LTTVLF 446
Cdd:cd06174 372 LAAILL 377
|
|
| MFS_FucP_like |
cd17394 |
Fucose permease and similar proteins of the Major Facilitator Superfamily of transporters; ... |
129-421 |
7.91e-09 |
|
Fucose permease and similar proteins of the Major Facilitator Superfamily of transporters; This subfamily is composed of L-fucose permease (also called L-fucose-proton symporter) and similar proteins such as glucose/galactose transporter and N-acetyl glucosamine transporter NagP. L-fucose permease facilitates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell; it can also transport L-galactose and D-arabinose. Glucose/galactose transporter functions in the uptake of of glucose and galactose. The FucP-like subfamily belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340952 [Multi-domain] Cd Length: 401 Bit Score: 57.62 E-value: 7.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 129 AALLTAMMSI-TGVSFgvLDTGGNVLILDLWGDKGAPHIQALHFSF-ALGAFLAPLLAKLAWGTTASAQNHTEPQLDRSA 206
Cdd:cd17394 91 GLFLIALFVLaSGLAL--LQTAANPYVTVLGPEETAARRLNLAQAFnSLGSTIAPLFGSYLILSGIPSTATALAAMSAAE 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 207 LNRSFEAASDSVLAVpddmnllwaYASIGTYVLVLSVFLFAPFFKKRSKQKKSAASAQGARRAKYHRALLCLLFLFFFFY 286
Cdd:cd17394 169 LQAYKTAELASVQLP---------YLGIALVLLLLAVLILLSKLPEIEAAEAEALGSKGTLLRLLKNPHLRLGVLAIFFY 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 287 VGAEVTYGSYVFSFATTHV-GMEESEAAGLNSIFWGTFAACRGLAIFFATLLQPGTMMVLCNIGSLASSFFLVLFDK-SP 364
Cdd:cd17394 240 VGAEVAIWSFLINYLMEYIaGLTETSAATFVSYYWGGFMVGRFLGTALLKKISPKKLLAVFALLGLLLLLGAIFTGGmVA 319
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 28570190 365 LCLWIASSVYGASMAAT-FPSGISWIEQYTtltgKSAAFILVGAALGLMATPALSGIL 421
Cdd:cd17394 320 LYALVLVGFFNSIMFPTiFSLALKGLGKHT----KTGSGLLVMAIVGGAVVPLIQGAV 373
|
|
| AraJ |
COG2814 |
Predicted arabinose efflux permease AraJ, MFS family [Carbohydrate transport and metabolism]; |
39-416 |
9.86e-07 |
|
Predicted arabinose efflux permease AraJ, MFS family [Carbohydrate transport and metabolism];
Pssm-ID: 442063 [Multi-domain] Cd Length: 348 Bit Score: 50.74 E-value: 9.86e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 39 RWFTTVVLNAAFLGMGVSAAVLGPTFPDLARNVNRNISSLSEIFVGRALGYLGGSVVGGVLFDCMNHFLLLGLSHLLTAA 118
Cdd:COG2814 8 RWLALLALALGAFLSGLGIGIVLPALPLIAADLGASPAQAGLVVTAYLLGAALGAPLAGRLADRFGRRRVLLLGLLLFAL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 119 GLYLTPFCKTAALLTAMMSITGVSFGVLDTGGNVLILDLWGDKGAPHIQALHFS-FALGAFLAPLLAklawgttasaqnh 197
Cdd:COG2814 88 GSLLCALAPSLWLLLAARFLQGLGAGALFPAALALIADLVPPERRGRALGLLGAgLGLGPALGPLLG------------- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 198 tepqldrsalnrsfeaasdSVLAVpddmNLLWAYASIGTYVLVLSVFLFAPFFKKRSKQKKSAASAQGARRAKYHRALLC 277
Cdd:COG2814 155 -------------------GLLAD----LFGWRWVFLVNAVLALLALLLLLRLLPESRPAARARLRGSLRELLRRPRLLL 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 278 LLFLFFFFYVGAeVTYGSYVFSFATTHVGMEESEAAGLNSIFWGTFAACRGLAIFFATLLQPGTMMVLCnIGSLASSFFL 357
Cdd:COG2814 212 LLLLAFLLGFGF-FALFTYLPLYLQEVLGLSASAAGLLLALFGLGGVLGALLAGRLADRFGRRRLLLIG-LLLLALGLLL 289
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 28570190 358 VLFDKSPLCLWIASSVYGASMAATFPSGISWIEQYTTLTGKSAAFILVGAALGLMATPA 416
Cdd:COG2814 290 LALAGSLWLLLLALFLLGFGFGLLFPLLQALVAELAPPEARGRASGLYNSAFFLGGPLA 348
|
|
| PRK03699 |
PRK03699 |
putative transporter; Provisional |
53-425 |
2.90e-04 |
|
putative transporter; Provisional
Pssm-ID: 235151 [Multi-domain] Cd Length: 394 Bit Score: 42.99 E-value: 2.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 53 MGVSAAVLGPTFPDLARNVNRNISSLSEIFVGRALGYLGGSVVGGVLfdcMNHF------LLLGLSHLLTAAGLYLTPfc 126
Cdd:PRK03699 19 TGALVIVTGMVMGPIAEYFNLPVSSMSNTFTFLNAGILISIFLNAWL---MEIIplkrqlIFGFALMILAVAGLMFSH-- 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 127 kTAALLTAMMSITGVSFGVLDTGGNVLILDLWGDKgaphIQALH-----FSFALGAFLAPLLAklAWgttasaqnhtepq 201
Cdd:PRK03699 94 -SLALFSIAMFVLGVVSGITMSIGTFLITHVYEGK----QRGSRllftdSFFSMAGMIFPIIA--AY------------- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 202 ldrsALNRSFEaasdsvlavpddmnLLWAYASIG-TYVLVLSVFLFAPFfkkrSKQKKSAASAQGARRAKYHRALLCLLF 280
Cdd:PRK03699 154 ----LLARSIE--------------WYWVYACIGlVYVAIFILTLFSEF----PALGKHAPKADKPVAKEKWGIGVLFLA 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 281 LFFFFYVGAEVTYGSYVFSFATTHVGMEESEAAGLNSIFWGtfAACRGLAIFFATL----LQpgTMMVLCNIGSLASSFF 356
Cdd:PRK03699 212 IAALLYILAQLTFISWVPEYAQKKFGMSLEDAGNLVSNFWM--AYMVGMWIFSFIVrffdLQ--RILTVLAGLALVLMYL 287
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 357 LVLFDKSPLCLWIASSvYGASMAATFPSGISWIEQYTTLTG-KSAAFILVGAALGLMATPALSGILQGHY 425
Cdd:PRK03699 288 FVNTDDPSHLLYAILG-LGFFSSAIYTTIITLGSQQTKVASpKLVNFILTCGTIGTMLTFVVTSPIVAHF 356
|
|
| MFS_1 |
pfam07690 |
Major Facilitator Superfamily; |
49-415 |
6.53e-04 |
|
Major Facilitator Superfamily;
Pssm-ID: 429598 [Multi-domain] Cd Length: 344 Bit Score: 42.02 E-value: 6.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 49 AFLGMGVSAAVLGPTFP-DLARNVNRNISSLSEIFVGRALGYLGGSVVGGVLFDCMNHFLLLGLSHLLTAAGLYLTPFCK 127
Cdd:pfam07690 4 AAFLAALGRSLLGPALPlLLAEDLGISPTEIGLLLTLFSLGYALAQPLAGRLSDRFGRRRVLLIGLLLFALGLLLLLFAS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 128 TAALLTAMMSITGVSFGVLDTGGNVLILDLWGDKGAPHIQAL-HFSFALGAFLAPLLAklawgttasaqnhtepqldrsa 206
Cdd:pfam07690 84 SLWLLLVLRVLQGLGAGALFPAALALIADWFPPEERGRALGLvSAGFGLGAALGPLLG---------------------- 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 207 lnrsfeaasdSVLAVPDDMNLLWAYASIGTYVLVLSVFLFAPFFKKRSKQKKSAASAQGARRAKYHRALLCLLFLFFFFY 286
Cdd:pfam07690 142 ----------GLLASLFGWRAAFLILAILSLLAAVLLLLPRPPPESKRPKPAEEARLSLIVAWKALLRDPVLWLLLALLL 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 287 VGAEVTYGSYVFSFATTHVGMEESEAAGLNSIFWGTFAACRGLAIFFATLLQPGTMMVLCNIGSLASSFFLVL--FDKSP 364
Cdd:pfam07690 212 FGFAFFGLLTYLPLYQEVLGLSALLAGLLLGLGGLLGAIGRLLLGRLSDRLGRRRRLLLALLLLILAALGLLLlsLTLSS 291
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 28570190 365 LCLWIASSVYGASMAATFPSGISWIEQY--TTLTGKSAAFILVGAALGLMATP 415
Cdd:pfam07690 292 LWLLLALLLLGFGFGLVFPALNALVSDLapKEERGTASGLYNTAGSLGGALGP 344
|
|
| NarK |
COG2223 |
Nitrate/nitrite transporter NarK [Inorganic ion transport and metabolism]; |
284-451 |
6.86e-04 |
|
Nitrate/nitrite transporter NarK [Inorganic ion transport and metabolism];
Pssm-ID: 441825 [Multi-domain] Cd Length: 392 Bit Score: 41.79 E-value: 6.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 284 FFYVGAEVTYGSYVFSFATTHVGMEESEAAGLNSIFWGTFAACRGLAIFFATLLQPGTMMVLCNIGSLASSFFLVLFDKS 363
Cdd:COG2223 215 FGTFGSFIGFSSWLPPYLVDQFGLSAATAGLLAALFALLGALGRPLGGWLSDRIGGRRVLLIVFALMALGLLLLALALGS 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 364 PLCLWIASSVYGASMAATFPSGISWIEQY--TTLTGKSAAFILVGAALGLMATPALSGILQGHYPDLPVILYMCLGSAVL 441
Cdd:COG2223 295 LWLFLVLFLLLGLALGGGNGAVFALVPDIfpTKNAGAVYGLVGAAGGLGGFLGPLLFGALLDATGSYTAAFLVFAVLALV 374
|
170
....*....|
gi 28570190 442 TTVLFPVMYK 451
Cdd:COG2223 375 ALVLTLLLYR 384
|
|
| MFS_MosC_like |
cd17393 |
Membrane protein MosC and similar proteins of the Major Facilitator Superfamily of ... |
48-197 |
1.76e-03 |
|
Membrane protein MosC and similar proteins of the Major Facilitator Superfamily of transporters; The gene encoding Sinorhizobium meliloti membrane protein MosC is part of the mos locus, which encodes the biosynthesis of the rhizopine 3-O-methyl-scyllo-inosamine. MosC belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.
Pssm-ID: 340951 [Multi-domain] Cd Length: 373 Bit Score: 40.70 E-value: 1.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 48 AAFLGMGVSAAVLGPTFPDLARNVNRNISSLSEIFVGRALGYLGGSVVGGVLFDCMNHFLLLGLSHLLTAAGLYLTPFCK 127
Cdd:cd17393 6 AFFFINGILMASWATRIPAIKDRLGLSDAALGLLLLALGVGALVAMPLAGRLVARFGSRRVTRLGALLLLLALLLLGLAP 85
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 128 TAALLTAMMSITGVSFGVLDTGGNVLILDLWGDKGAPHIQALHFSFALGAFLAPLLAKLAWGTTASAQNH 197
Cdd:cd17393 86 SVPALALALFLFGAANGALDVAMNAQGVAVERAYGRPIMSSLHAMWSLGGLAGALLGAAAIGAGVSPGVH 155
|
|
| UhpC |
COG2271 |
Sugar phosphate permease [Carbohydrate transport and metabolism]; |
32-451 |
9.18e-03 |
|
Sugar phosphate permease [Carbohydrate transport and metabolism];
Pssm-ID: 441872 [Multi-domain] Cd Length: 363 Bit Score: 38.31 E-value: 9.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 32 DQVGRTLRWFTTVVLNAAFLGMGVSAAVLGPTFPDLARNVNRNISSLSEIFVGRALGYLGGSVVGGVLFDCMNHFLLLGL 111
Cdd:COG2271 1 ARAPSRYRWRILALLFLAYFLNYLDRSNLSVAAPPLQADLGLSAAQLGLLASAFFLGYALGQIPAGLLADRFGRRRVLAI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 112 SHLLTAAGLYLTPFCKTAALLTAMMSITGVSFGVLDTGGNVLILDLWGDKGAPHIQALHFSFA-LGAFLAPLLaklawgt 190
Cdd:COG2271 81 GLLLWGLATLLFGFATSFWQLLLLRFLLGLGEAGFFPAALKLIAEWFPPKERGRALGIFNAGGpLGGALAPPL------- 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 191 tasaqnhtepqldrsalnrsfeaasdsVLAVPDDMNLLWAYASIGTYVLVLSVFLFAPFFkkrskqkksaasaqgarrak 270
Cdd:COG2271 154 ---------------------------LGWLLAAFGWRAAFLILGLPGLLLALLRFWLLA-------------------- 186
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 271 yhrallcllfLFFFFYVGAEVTYGSYVFSFATTHVGMEESEAAGLNSIFWGTFAACRGLAIFFATLLQPG--TMMVLCNI 348
Cdd:COG2271 187 ----------LAYFLVYFALYGFLTWLPTYLVEVRGLSLAQAGLLLSLPFLAGIVGSLLGGWLSDRLGRRrkLVLAIGLL 256
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28570190 349 GSLASSFFLVLFDkSPLCLWIASSVYGASMAATFPSGISWIEQY--TTLTGKSAAFILVGAALGLMATPALSGILQGHYp 426
Cdd:COG2271 257 LAALALLLLALLP-SPALAIALLFLAGFGLGGAFGLLWALAAELfpKKARGTASGLVNTFGFLGGALGPLLVGYLLDAT- 334
|
410 420
....*....|....*....|....*
gi 28570190 427 DLPVILYMCLGSAVLTTVLFPVMYK 451
Cdd:COG2271 335 GYQAAFLLLAALALLAALLALLLLR 359
|
|
| |
