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Conserved domains on  [gi|30425288|ref|NP_780731|]
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protein ELFN1 isoform 1 precursor [Mus musculus]

Protein Classification

LRR_8 and LRRCT domain-containing protein( domain architecture ID 12158289)

LRR_8 and LRRCT domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR_8 pfam13855
Leucine rich repeat;
85-144 1.91e-14

Leucine rich repeat;


:

Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 68.32  E-value: 1.91e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288    85 NLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLSKLEYLYLQANLI 144
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
40-190 2.67e-14

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 75.74  E-value: 2.67e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288  40 WLAICSQNQPPYEAIPQQINNTIVDLRLNEnrirsvqyaSLSRFGNLTYLNLTKNEIGYIEDgAFSGQFNLQVLQLGYNR 119
Cdd:COG4886  78 SLLLLSLLLLGLTDLGDLTNLTELDLSGNE---------ELSNLTNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQ 147

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30425288 120 LRNLTEGmLRGLSKLEYLYLQANLIEVVmASAFWECPNIVNIDLSMNRIQQLgSGTFAGLTKLSVCEIYSN 190
Cdd:COG4886 148 LTDLPEP-LGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGN 215
LRRCT smart00082
Leucine rich repeat C-terminal domain;
190-228 1.43e-06

Leucine rich repeat C-terminal domain;


:

Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 45.88  E-value: 1.43e-06
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 30425288    190 NPFYCSCELLGFLRWLAAFTnATQTHDRVQCESPPVYAG 228
Cdd:smart00082   1 NPFICDCELRWLLRWLQANE-HLQDPVDLRCASPSSLRG 38
 
Name Accession Description Interval E-value
LRR_8 pfam13855
Leucine rich repeat;
85-144 1.91e-14

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 68.32  E-value: 1.91e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288    85 NLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLSKLEYLYLQANLI 144
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
40-190 2.67e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 75.74  E-value: 2.67e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288  40 WLAICSQNQPPYEAIPQQINNTIVDLRLNEnrirsvqyaSLSRFGNLTYLNLTKNEIGYIEDgAFSGQFNLQVLQLGYNR 119
Cdd:COG4886  78 SLLLLSLLLLGLTDLGDLTNLTELDLSGNE---------ELSNLTNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQ 147

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30425288 120 LRNLTEGmLRGLSKLEYLYLQANLIEVVmASAFWECPNIVNIDLSMNRIQQLgSGTFAGLTKLSVCEIYSN 190
Cdd:COG4886 148 LTDLPEP-LGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGN 215
LRRCT smart00082
Leucine rich repeat C-terminal domain;
190-228 1.43e-06

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 45.88  E-value: 1.43e-06
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 30425288    190 NPFYCSCELLGFLRWLAAFTnATQTHDRVQCESPPVYAG 228
Cdd:smart00082   1 NPFICDCELRWLLRWLQANE-HLQDPVDLRCASPSSLRG 38
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 65-147 1.54e-06

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 49.78  E-value: 1.54e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288  65 LRLNENRIRSVQyaSLSRFGNLTYLNLTKNEIGYIEDgaFSGQFNLQVLQLGYNRLRNLtEGmLRGLSKLEYLYLQANLI 144
Cdd:cd21340   7 LYLNDKNITKID--NLSLCKNLKVLYLYDNKITKIEN--LEFLTNLTHLYLQNNQIEKI-EN-LENLVNLKKLYLGGNRI 80


                ...
gi 30425288 145 EVV 147
Cdd:cd21340  81 SVV 83
PCC TIGR00864
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ...
 162-233 1.98e-06

polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.


Pssm-ID: 188093 [Multi-domain]  Cd Length: 2740  Bit Score: 52.01  E-value: 1.98e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 30425288    162 DLSMNRIQQLGSGTFAGLTKLSVCEIYSNPFYCSCELLGFLRWLAAFTNATQTHDRVQCESPPVYAGYFLLG 233
Cdd:TIGR00864    1 DISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVRQPEAALCAGPGALAGQPLLG 72
LRR_8 pfam13855
Leucine rich repeat;
132-182 4.58e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 41.74  E-value: 4.58e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 30425288   132 SKLEYLYLQANLIEVVMASAFWECPNIVNIDLSMNRIQQLGSGTFAGLTKL 182
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSL 51
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 85-168 1.65e-04

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 44.78  E-value: 1.65e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288  85 NLTYLNLTKNEIGyiEDGA------FSGQFNLQVLQLGYNRL-----RNLTEGmLRGLSKLEYLYLQANLIEVV----MA 149
Cdd:COG5238 265 TVETLYLSGNQIG--AEGAialakaLQGNTTLTSLDLSVNRIgdegaIALAEG-LQGNKTLHTLNLAYNGIGAQgaiaLA 341

                        90
                ....*....|....*....
gi 30425288 150 SAFWECPNIVNIDLSMNRI 168
Cdd:COG5238 342 KALQENTTLHSLDLSDNQI 360
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 86-190 5.25e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 40.60  E-value: 5.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288   86 LTYLNLTKNEI-GYIEDgaFSGQFNLQVLQLGYNRLRNLTEGMLRGLSKLEYLYLQANLIEVVMASAFWECPNIVNIDLS 164
Cdd:PLN00113 454 LQMLSLARNKFfGGLPD--SFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLS 531

                         90       100
                 ....*....|....*....|....*.
gi 30425288  165 MNRIQQLGSGTFAGLTKLSVCEIYSN 190
Cdd:PLN00113 532 HNQLSGQIPASFSEMPVLSQLDLSQN 557
 
Name Accession Description Interval E-value
LRR_8 pfam13855
Leucine rich repeat;
85-144 1.91e-14

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 68.32  E-value: 1.91e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288    85 NLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLSKLEYLYLQANLI 144
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
40-190 2.67e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 75.74  E-value: 2.67e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288  40 WLAICSQNQPPYEAIPQQINNTIVDLRLNEnrirsvqyaSLSRFGNLTYLNLTKNEIGYIEDgAFSGQFNLQVLQLGYNR 119
Cdd:COG4886  78 SLLLLSLLLLGLTDLGDLTNLTELDLSGNE---------ELSNLTNLESLDLSGNQLTDLPE-ELANLTNLKELDLSNNQ 147

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30425288 120 LRNLTEGmLRGLSKLEYLYLQANLIEVVmASAFWECPNIVNIDLSMNRIQQLgSGTFAGLTKLSVCEIYSN 190
Cdd:COG4886 148 LTDLPEP-LGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGN 215
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
65-210 2.84e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 75.74  E-value: 2.84e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288  65 LRLNENRIRSVQyASLSRFGNLTYLNLTKNEIGYIEDgAFSGQFNLQVLQLGYNRLRNLTEGmLRGLSKLEYLYLQANLI 144
Cdd:COG4886 118 LDLSGNQLTDLP-EELANLTNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNNQLTDLPEE-LGNLTNLKELDLSNNQI 194

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 30425288 145 EvVMASAFWECPNIVNIDLSMNRIQQLgSGTFAGLTKLSVCEIYSNPfycscelLGFLRWLAAFTN 210
Cdd:COG4886 195 T-DLPEPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQ-------LTDLPELGNLTN 251
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
44-202 5.14e-12

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 68.81  E-value: 5.14e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288  44 CSQNQppYEAIPQQINN--TIVDLRLNENRIRSVQyASLSRFGNLTYLNLTKNEIGYIEDgAFSGQFNLQVLQLGYNRLR 121
Cdd:COG4886 166 LSNNQ--LTDLPEELGNltNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDLPE-PLANLTNLETLDLSNNQLT 241

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288 122 NLTEgmLRGLSKLEYLYLQANLIEVVmaSAFWECPNIVNIDLSMNRIQQLGSGTFAGLTKLSVCEIYSNPFYCSCELLGF 201
Cdd:COG4886 242 DLPE--LGNLTNLEELDLSNNQLTDL--PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILL 317


                .
gi 30425288 202 L 202
Cdd:COG4886 318 L 318
LRR_8 pfam13855
Leucine rich repeat;
109-168 8.21e-10

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 55.22  E-value: 8.21e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288   109 NLQVLQLGYNRLRNLTEGMLRGLSKLEYLYLQANLIEVVMASAFWECPNIVNIDLSMNRI 168
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
65-120 7.94e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 49.45  E-value: 7.94e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 30425288    65 LRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRL 120
Cdd:pfam13855   6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRRCT smart00082
Leucine rich repeat C-terminal domain;
190-228 1.43e-06

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 45.88  E-value: 1.43e-06
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 30425288    190 NPFYCSCELLGFLRWLAAFTnATQTHDRVQCESPPVYAG 228
Cdd:smart00082   1 NPFICDCELRWLLRWLQANE-HLQDPVDLRCASPSSLRG 38
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 65-147 1.54e-06

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 49.78  E-value: 1.54e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288  65 LRLNENRIRSVQyaSLSRFGNLTYLNLTKNEIGYIEDgaFSGQFNLQVLQLGYNRLRNLtEGmLRGLSKLEYLYLQANLI 144
Cdd:cd21340   7 LYLNDKNITKID--NLSLCKNLKVLYLYDNKITKIEN--LEFLTNLTHLYLQNNQIEKI-EN-LENLVNLKKLYLGGNRI 80


                ...
gi 30425288 145 EVV 147
Cdd:cd21340  81 SVV 83
PCC TIGR00864
polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) ...
 162-233 1.98e-06

polycystin cation channel protein; The Polycystin Cation Channel (PCC) Family (TC 1.A.5) Polycystin is a huge protein of 4303aas. Its repeated leucine-rich (LRR) segment is found in many proteins. It contains 16 polycystic kidney disease (PKD) domains, one LDL-receptor class A domain, one C-type lectin family domain, and 16-18 putative TMSs in positions between residues 2200 and 4100. Polycystin-L has been shown to be a cation (Na+, K+ and Ca2+) channel that is activated by Ca2+. Two members of the PCC family (polycystin 1 and 2) are mutated in autosomal dominant polycystic kidney disease, and polycystin-L is deleted in mice with renal and retinal defects. Note: this model is restricted to the amino half.


Pssm-ID: 188093 [Multi-domain]  Cd Length: 2740  Bit Score: 52.01  E-value: 1.98e-06
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 30425288    162 DLSMNRIQQLGSGTFAGLTKLSVCEIYSNPFYCSCELLGFLRWLAAFTNATQTHDRVQCESPPVYAGYFLLG 233
Cdd:TIGR00864    1 DISNNKISTIEEGICANLCNLSEIDLSGNPFECDCGLARLPRWAEEKGVKVRQPEAALCAGPGALAGQPLLG 72
LRR_5 pfam13306
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ...
 85-195 2.15e-06

BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.


Pssm-ID: 463839 [Multi-domain]  Cd Length: 127  Bit Score: 47.54  E-value: 2.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288    85 NLTYLNLTKNeIGYIEDGAFSGQFNLQVLQLgYNRLRNLTEGMLRGlSKLEYLYLQANL--IEVvmaSAFWECPNIVNID 162
Cdd:pfam13306  12 SLTSITIPSS-LTSIGEYAFSNCTSLKSITL-PSSLTSIGSYAFYN-CSLTSITIPSSLtsIGE---YAFSNCSNLKSIT 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 30425288   163 LSmNRIQQLGSGTFAG--LTKLSVC----EIYSNPFY-CS 195
Cdd:pfam13306  86 LP-SNLTSIGSYAFSNcsLKSITIPssvtTIGSYAFSnCS 124
LRR_8 pfam13855
Leucine rich repeat;
132-182 4.58e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 41.74  E-value: 4.58e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 30425288   132 SKLEYLYLQANLIEVVMASAFWECPNIVNIDLSMNRIQQLGSGTFAGLTKL 182
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSL 51
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 85-168 1.65e-04

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 44.78  E-value: 1.65e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288  85 NLTYLNLTKNEIGyiEDGA------FSGQFNLQVLQLGYNRL-----RNLTEGmLRGLSKLEYLYLQANLIEVV----MA 149
Cdd:COG5238 265 TVETLYLSGNQIG--AEGAialakaLQGNTTLTSLDLSVNRIgdegaIALAEG-LQGNKTLHTLNLAYNGIGAQgaiaLA 341

                        90
                ....*....|....*....
gi 30425288 150 SAFWECPNIVNIDLSMNRI 168
Cdd:COG5238 342 KALQENTTLHSLDLSDNQI 360
RNA1 COG5238
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ...
 34-172 2.61e-04

Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];


Pssm-ID: 444072 [Multi-domain]  Cd Length: 434  Bit Score: 44.40  E-value: 2.61e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288  34 GDKGFVWLAicsqnqppyEAIpqQINNTIVDLRLNENRIrSVQYA-----SLSRFGNLTYLNLTKNEIGyiEDGAFSGQF 108
Cdd:COG5238 249 GDEGVIALA---------EAL--KNNTTVETLYLSGNQI-GAEGAialakALQGNTTLTSLDLSVNRIG--DEGAIALAE 314

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288 109 NLQ------VLQLGYNRLRNltEGM------LRGLSKLEYLYLQANLIEVVMASAFWE----CPNIVNIDLSMNRIQQLG 172
Cdd:COG5238 315 GLQgnktlhTLNLAYNGIGA--QGAialakaLQENTTLHSLDLSDNQIGDEGAIALAKylegNTTLRELNLGKNNIGKQG 392
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 109-142 2.38e-03

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 36.45  E-value: 2.38e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 30425288   109 NLQVLQLGYNRLRNLteGMLRGLSKLEYLYLQAN 142
Cdd:pfam12799   2 NLEVLDLSNNQITDI--PPLAKLPNLETLDLSGN 33
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 86-190 5.25e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 40.60  E-value: 5.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30425288   86 LTYLNLTKNEI-GYIEDgaFSGQFNLQVLQLGYNRLRNLTEGMLRGLSKLEYLYLQANLIEVVMASAFWECPNIVNIDLS 164
Cdd:PLN00113 454 LQMLSLARNKFfGGLPD--SFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLS 531

                         90       100
                 ....*....|....*....|....*.
gi 30425288  165 MNRIQQLGSGTFAGLTKLSVCEIYSN 190
Cdd:PLN00113 532 HNQLSGQIPASFSEMPVLSQLDLSQN 557
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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