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Conserved domains on  [gi|255759902|ref|NP_776101|]
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amine oxidase [flavin-containing] A [Mus musculus]

Protein Classification

flavin monoamine oxidase family protein( domain architecture ID 11440890)

flavin monoamine oxidase family protein functions as an oxidoreductase that catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

CATH:  3.50.50.60|1.10.405.10
EC:  1.-.-.-
Gene Ontology:  GO:0000166|GO:0016491
SCOP:  4000128

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
10-464 1.65e-128

Monoamine oxidase [Amino acid transport and metabolism];


:

Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 381.96  E-value: 1.65e-128
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  10 TGHMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVK-WVDVGGAYVGPTQNRILRLSKELGIET 88
Cdd:COG1231    4 RARGKDVVIVGAGLAGLAAARELRKAGLDVTVLEARDRVGGRVWTLRFGDDGlYAELGAMRIPPSHTNLLALARELGLPL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  89 YK-VNVNERLVQYVKGKTYPFRGAfppvwnPLAYLDYNNLW-RTMDDMGKEIPvdaPWQARhAEEWDKITMKDLIDKICW 166
Cdd:COG1231   84 EPfPNENGNALLYLGGKRVRAGEI------AADLRGVAELLaKLLRALAAALD---PWAHP-AAELDRESLAEWLRRNGA 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 167 TKTAREFAYLFVNINVTSEPHEVSALWFLWYVRQCGGtsrifsvtnGGQERKFVGGSGQISEQIMVLLGDKVKLSSPVTY 246
Cdd:COG1231  154 SPSARRLLGLLGAGEYGADPDELSLLDLLRYAASAGG---------GAQQFRIVGGMDQLPRALAAELGDRIRLGAPVTR 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 247 IDQTDDNIIIETLNHEHYECKYVISAIPPVLTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDYCGCMII 326
Cdd:COG1231  225 IRQDGDGVTVTTDDGGTVRADAVIVTVPPSVLRRIEFDPPLPAAKRAAIQRLPYGAAIKVFLQFDRPFWEEDGLYGGISL 304

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 327 EDEeaPISITLDDTKP-DGSMPAIMGFILARKAERLAKLHKDIRKRKICELYAKVLGSqEALSPVHYEEKNWCEEQYSGG 405
Cdd:COG1231  305 TDL--PIRQTWYPSNGpDGGAGVLLGYVGGDDARALAALSPEERVAAALEQLARIFGV-YAAEPVDYVSTDWGRDPWSRG 381

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 255759902 406 CYtAYFPPGIMTLYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALG 464
Cdd:COG1231  382 AY-AAAPPGQLTAAGPALAEPDGRIHFAGEHTSDEWPGWVEGALESGERAAAEILARLG 439
 
Name Accession Description Interval E-value
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
10-464 1.65e-128

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 381.96  E-value: 1.65e-128
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  10 TGHMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVK-WVDVGGAYVGPTQNRILRLSKELGIET 88
Cdd:COG1231    4 RARGKDVVIVGAGLAGLAAARELRKAGLDVTVLEARDRVGGRVWTLRFGDDGlYAELGAMRIPPSHTNLLALARELGLPL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  89 YK-VNVNERLVQYVKGKTYPFRGAfppvwnPLAYLDYNNLW-RTMDDMGKEIPvdaPWQARhAEEWDKITMKDLIDKICW 166
Cdd:COG1231   84 EPfPNENGNALLYLGGKRVRAGEI------AADLRGVAELLaKLLRALAAALD---PWAHP-AAELDRESLAEWLRRNGA 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 167 TKTAREFAYLFVNINVTSEPHEVSALWFLWYVRQCGGtsrifsvtnGGQERKFVGGSGQISEQIMVLLGDKVKLSSPVTY 246
Cdd:COG1231  154 SPSARRLLGLLGAGEYGADPDELSLLDLLRYAASAGG---------GAQQFRIVGGMDQLPRALAAELGDRIRLGAPVTR 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 247 IDQTDDNIIIETLNHEHYECKYVISAIPPVLTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDYCGCMII 326
Cdd:COG1231  225 IRQDGDGVTVTTDDGGTVRADAVIVTVPPSVLRRIEFDPPLPAAKRAAIQRLPYGAAIKVFLQFDRPFWEEDGLYGGISL 304

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 327 EDEeaPISITLDDTKP-DGSMPAIMGFILARKAERLAKLHKDIRKRKICELYAKVLGSqEALSPVHYEEKNWCEEQYSGG 405
Cdd:COG1231  305 TDL--PIRQTWYPSNGpDGGAGVLLGYVGGDDARALAALSPEERVAAALEQLARIFGV-YAAEPVDYVSTDWGRDPWSRG 381

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 255759902 406 CYtAYFPPGIMTLYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALG 464
Cdd:COG1231  382 AY-AAAPPGQLTAAGPALAEPDGRIHFAGEHTSDEWPGWVEGALESGERAAAEILARLG 439
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 23-460 6.32e-80

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 257.03  E-value: 6.32e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902   23 ISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVkWVDVGGAYVGPTQNRILRLSKELGIET---YKVNVNERLVQ 99
Cdd:pfam01593   1 LAGLAAARELLRAGHDVTVLEARDRVGGRIRTVRDDGF-LIELGAMWFHGAQPPLLALLKELGLEDrlvLPDPAPFYTVL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  100 YVKGKTYPFRGAFPP-VWNPLAYLDYNNLW-----RTMDDMGKEIPVDAPWQARHAEEWDKITMKD-LIDKICWTKTARE 172
Cdd:pfam01593  80 FAGGRRYPGDFRRVPaGWEGLLEFGRLLSIpeklrLGLAALASDALDEFDLDDFSLAESLLFLGRRgPGDVEVWDRLIDP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  173 FAYLFVNINVT------SEPHEVSALWFLWYVRQcggtsrifsvtNGGQERKFVGGSGQISEQI-MVLLGDKVKLSSPVT 245
Cdd:pfam01593 160 ELFAALPFASGafagdpSELSAGLALPLLWALLG-----------EGGSLLLPRGGLGALPDALaAQLLGGDVRLNTRVR 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  246 YIDQTDDNIIIETLNHEHYECKYVISAIPP-VLtAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKD---YC 321
Cdd:pfam01593 229 SIDREGDGVTVTLTDGEVIEADAVIVTVPLgVL-KRILFTPPLPPEKARAIRNLGYGPVNKVHLEFDRKFWPDLGllgLL 307

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  322 GCMIIEDEEAPISITLDDTKPDGSMPAIMGFI-LARKAERLAKLHKDIRKRKICELYAKVLGSqEALSPVHYEEKNWCEE 400
Cdd:pfam01593 308 SELLTGLGTAFSWLTFPNRAPPGKGLLLLVYVgPGDRARELEGLSDEELLQAVLRDLRKLFGE-EAPEPLRVLVSDWHTD 386

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  401 QYSGGCYTAYFPPGIMTLYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVL 460
Cdd:pfam01593 387 PWPRGSYSLPQYGPGHDDYRPLARTPDPGLFFAGEHTSTGYPGTVEGAIESGRRAARAVL 446
PLN02268 PLN02268
probable polyamine oxidase
 16-458 2.18e-22

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 99.76  E-value: 2.18e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKwVDVGGAYV-GPTQ-NRILRLSKELGIETYKVNV 93
Cdd:PLN02268   3 VIVIGGGIAGIAAARALHDASFKVTLLESRDRIGGRVHTDYSFGFP-VDMGASWLhGVCNeNPLAPLIGRLGLPLYRTSG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  94 NerlvqyvkgktypfrgafppvwNPLAYlDYNNLWRTMDDM-GKEIPvdaPWQARHAEEWDKITMKDlidkicwTKTAR- 171
Cdd:PLN02268  82 D----------------------NSVLY-DHDLESYALFDMdGNQVP---QELVTKVGETFERILEE-------TEKVRd 128

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 172 EFAYLF-----VNINVTSEP--------HEVsalwFLWYVRQCGG-----TSRIfSVTNGGQERKFVGGSGQIS---EQI 230
Cdd:PLN02268 129 EHEEDMsllqaISIVLERHPelrleglaHEV----LQWYLCRMEGwfaadADTI-SLKSWDQEELLEGGHGLMVrgyDPV 203

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 231 MVLL--GDKVKLSSPVTYIDQTDDNIIIETLNHEHYECKYVISAIP-PVLTAK-IHFKPELPPERNQLIQRLPMGAVIKC 306
Cdd:PLN02268 204 INTLakGLDIRLNHRVTKIVRRYNGVKVTVEDGTTFVADAAIIAVPlGVLKANiIKFEPELPEWKEEAISDLGVGIENKI 283

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 307 MVYYKEAFWKKKDYCGCMiiedeeAPISIT----LDDTKPDGS-----MPAimgfilARKAERLAKLHKDIRKRKICELY 377
Cdd:PLN02268 284 ALHFDSVFWPNVEFLGVV------APTSYGcsyfLNLHKATGHpvlvyMPA------GRLARDIEKLSDEAAANFAMSQL 351

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 378 AKVLgsQEALSPVHYEEKNWCEEQYSGGCYTAYFPPGIMTLYGRvIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAR 457
Cdd:PLN02268 352 KKML--PDATEPVQYLVSRWGSDPNSLGCYSYDLVGKPHDLYER-LRAPVDNLFFAGEATSSDFPGSVHGAYSTGVMAAE 428


                 .
gi 255759902 458 E 458
Cdd:PLN02268 429 E 429
proto_IX_ox TIGR00562
protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a ...
 13-298 1.35e-11

protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a precursor of heme and chlorophyll. Bacillus subtilis HemY also has coproporphyrinogen III to coproporphyrin III oxidase activity in a heterologous expression system, although the role for this activity in vivo is unclear. This protein is a flavoprotein and has a beta-alpha-beta dinucleotide binding motif near the amino end. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 213540 [Multi-domain]  Cd Length: 462  Bit Score: 66.78  E-value: 1.35e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902   13 MFDVVVIGGGISGLAAA----KLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWvDVGGAYVGPTQNRILRLSKELGIET 88
Cdd:TIGR00562   2 KKHVVIIGGGISGLCAAyyleKEIPELPVELTLVEASDRVGGKIQTVKEDGYLI-ERGPDSFLERKKSAPDLVKDLGLEH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902   89 YKVN--VNERLVQYVKGKTYPfrgaFPPVWNPLAYLDYNNL---------WRTMDDMGKEIPVDAPWQARHAEEW----- 152
Cdd:TIGR00562  81 VLVSdaTGQRYVLVNRGKLMP----VPTKIAPFVKTGLFSLggklragmdFIRPASPGKDESVEEFVRRRFGDEVvenli 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  153 ------------DKITMKDLIDKIcwTKTAREFAYLFVNINVTSEPHEvsalwflwyvrqcGGTSRIFSVTNGGQERKFV 220
Cdd:TIGR00562 157 epllsgiyagdpSKLSLKSTFPKF--YQTEQKHGSLILGMKKTRNLPQ-------------GSGLQLTAKKQGQDFQTLA 221

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 255759902  221 GGSGQISEQIMVLLG-DKVKLSSPVTYIDQTDDNIIIETLNHEHYECKYVISAIPPVLTAKIhfkpeLPPERNQLIQRL 298
Cdd:TIGR00562 222 TGLETLPEEIEKRLKlTKVYKGTKVTKLSHRGSNYTLELDNGVTVETDSVVVTAPHKAAAGL-----LSELSNSASSHL 295
AlaDh_PNT_C smart01002
Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the ...
 16-70 4.57e-03

Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the NAD-dependent reversible reductive amination of pyruvate into alanine.


Pssm-ID: 214966 [Multi-domain]  Cd Length: 149  Bit Score: 37.87  E-value: 4.57e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 255759902    16 VVVIGGGISGLAAAKLLSEYKINVLVL--------EARDRVGGRTYTVR------NEHVKWVD--VGGAYV 70
Cdd:smart01002  23 VVVIGAGVVGLGAAATAKGLGAEVTVLdvrparlrQLESLLGARFTTLYsqaellEEAVKEADlvIGAVLI 93
 
Name Accession Description Interval E-value
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
10-464 1.65e-128

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 381.96  E-value: 1.65e-128
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  10 TGHMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVK-WVDVGGAYVGPTQNRILRLSKELGIET 88
Cdd:COG1231    4 RARGKDVVIVGAGLAGLAAARELRKAGLDVTVLEARDRVGGRVWTLRFGDDGlYAELGAMRIPPSHTNLLALARELGLPL 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  89 YK-VNVNERLVQYVKGKTYPFRGAfppvwnPLAYLDYNNLW-RTMDDMGKEIPvdaPWQARhAEEWDKITMKDLIDKICW 166
Cdd:COG1231   84 EPfPNENGNALLYLGGKRVRAGEI------AADLRGVAELLaKLLRALAAALD---PWAHP-AAELDRESLAEWLRRNGA 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 167 TKTAREFAYLFVNINVTSEPHEVSALWFLWYVRQCGGtsrifsvtnGGQERKFVGGSGQISEQIMVLLGDKVKLSSPVTY 246
Cdd:COG1231  154 SPSARRLLGLLGAGEYGADPDELSLLDLLRYAASAGG---------GAQQFRIVGGMDQLPRALAAELGDRIRLGAPVTR 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 247 IDQTDDNIIIETLNHEHYECKYVISAIPPVLTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDYCGCMII 326
Cdd:COG1231  225 IRQDGDGVTVTTDDGGTVRADAVIVTVPPSVLRRIEFDPPLPAAKRAAIQRLPYGAAIKVFLQFDRPFWEEDGLYGGISL 304

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 327 EDEeaPISITLDDTKP-DGSMPAIMGFILARKAERLAKLHKDIRKRKICELYAKVLGSqEALSPVHYEEKNWCEEQYSGG 405
Cdd:COG1231  305 TDL--PIRQTWYPSNGpDGGAGVLLGYVGGDDARALAALSPEERVAAALEQLARIFGV-YAAEPVDYVSTDWGRDPWSRG 381

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 255759902 406 CYtAYFPPGIMTLYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALG 464
Cdd:COG1231  382 AY-AAAPPGQLTAAGPALAEPDGRIHFAGEHTSDEWPGWVEGALESGERAAAEILARLG 439
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
 23-460 6.32e-80

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 257.03  E-value: 6.32e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902   23 ISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVkWVDVGGAYVGPTQNRILRLSKELGIET---YKVNVNERLVQ 99
Cdd:pfam01593   1 LAGLAAARELLRAGHDVTVLEARDRVGGRIRTVRDDGF-LIELGAMWFHGAQPPLLALLKELGLEDrlvLPDPAPFYTVL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  100 YVKGKTYPFRGAFPP-VWNPLAYLDYNNLW-----RTMDDMGKEIPVDAPWQARHAEEWDKITMKD-LIDKICWTKTARE 172
Cdd:pfam01593  80 FAGGRRYPGDFRRVPaGWEGLLEFGRLLSIpeklrLGLAALASDALDEFDLDDFSLAESLLFLGRRgPGDVEVWDRLIDP 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  173 FAYLFVNINVT------SEPHEVSALWFLWYVRQcggtsrifsvtNGGQERKFVGGSGQISEQI-MVLLGDKVKLSSPVT 245
Cdd:pfam01593 160 ELFAALPFASGafagdpSELSAGLALPLLWALLG-----------EGGSLLLPRGGLGALPDALaAQLLGGDVRLNTRVR 228

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  246 YIDQTDDNIIIETLNHEHYECKYVISAIPP-VLtAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKD---YC 321
Cdd:pfam01593 229 SIDREGDGVTVTLTDGEVIEADAVIVTVPLgVL-KRILFTPPLPPEKARAIRNLGYGPVNKVHLEFDRKFWPDLGllgLL 307

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  322 GCMIIEDEEAPISITLDDTKPDGSMPAIMGFI-LARKAERLAKLHKDIRKRKICELYAKVLGSqEALSPVHYEEKNWCEE 400
Cdd:pfam01593 308 SELLTGLGTAFSWLTFPNRAPPGKGLLLLVYVgPGDRARELEGLSDEELLQAVLRDLRKLFGE-EAPEPLRVLVSDWHTD 386

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  401 QYSGGCYTAYFPPGIMTLYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVL 460
Cdd:pfam01593 387 PWPRGSYSLPQYGPGHDDYRPLARTPDPGLFFAGEHTSTGYPGTVEGAIESGRRAARAVL 446
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 13-463 3.16e-24

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 105.30  E-value: 3.16e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  13 MFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVkWVDVGG-AYVgPTQNRILRLSKELGIETYKV 91
Cdd:COG1232    1 MKRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVGGLIRTVEVDGF-RIDRGPhSFL-TRDPEVLELLRELGLGDELV 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  92 NVNERLVQ-YVKGKTYPF-RGAFPPVWNPL--------AYLDYnnlWRTMDDMGKEIPVdAPWQARH--AEEWDKItMKD 159
Cdd:COG1232   79 WPNTRKSYiYYGGKLHPLpQGPLALLRSPLlslagklrALLEL---LAPRRPPGEDESL-AEFVRRRfgREVYERL-VEP 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 160 LIDKIcwtktareFAYlfvninvtsEPHEVSALWFLWYVRQ---------CGGTSRIFSVTNGGQERKFVGGSGQISEQI 230
Cdd:COG1232  154 LLEGV--------YAG---------DPDELSADWAFPRLKRlelehgsliKGALALRKGAKAGEVFGYLRGGLGTLVEAL 216

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 231 MVLLGD-KVKLSSPVTYIDQTDDNIIIETLNHEHYECKYVISAIPPVLTAKIhFKPeLPPERNQLIQRLPMGAVIkcMVY 309
Cdd:COG1232  217 AEALEAgEIRLGTRVTAIEREGGGWRVTTSDGETIEADAVVSATPAPALARL-LAP-LPPEVAAALAGIPYASVA--VVA 292

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 310 --YKEAFWKKKDYCGCMIIEDEEAPIS-ITLDDTK-----PDG--SMPAIMGFilARKAERLAKLHKDIRKRKICELyAK 379
Cdd:COG1232  293 lgFDRPDLPPPDGFGWLVPRDEGVPILaVTFSSNKwphraPDGkvLLRLEVGG--AGDPELWQLSDEELVALALADL-RK 369

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 380 VLGSQEAlsPVHYEEKNWcEE---QYSGGcYTAYFPPgimtlygrvIRQPVGR---IYFAGtetaTQWSGY-MEGAVEAG 452
Cdd:COG1232  370 LLGIDAE--PVDTRVVRW-PKaypQYTVG-HLERVAA---------IREALAAlpgLYLAG----RAYDGVgLPDCIRSG 432

                        490
                 ....*....|.
gi 255759902 453 ERAAREVLNAL 463
Cdd:COG1232  433 REAAERILAEL 443
PLN02268 PLN02268
probable polyamine oxidase
 16-458 2.18e-22

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 99.76  E-value: 2.18e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKwVDVGGAYV-GPTQ-NRILRLSKELGIETYKVNV 93
Cdd:PLN02268   3 VIVIGGGIAGIAAARALHDASFKVTLLESRDRIGGRVHTDYSFGFP-VDMGASWLhGVCNeNPLAPLIGRLGLPLYRTSG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  94 NerlvqyvkgktypfrgafppvwNPLAYlDYNNLWRTMDDM-GKEIPvdaPWQARHAEEWDKITMKDlidkicwTKTAR- 171
Cdd:PLN02268  82 D----------------------NSVLY-DHDLESYALFDMdGNQVP---QELVTKVGETFERILEE-------TEKVRd 128

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 172 EFAYLF-----VNINVTSEP--------HEVsalwFLWYVRQCGG-----TSRIfSVTNGGQERKFVGGSGQIS---EQI 230
Cdd:PLN02268 129 EHEEDMsllqaISIVLERHPelrleglaHEV----LQWYLCRMEGwfaadADTI-SLKSWDQEELLEGGHGLMVrgyDPV 203

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 231 MVLL--GDKVKLSSPVTYIDQTDDNIIIETLNHEHYECKYVISAIP-PVLTAK-IHFKPELPPERNQLIQRLPMGAVIKC 306
Cdd:PLN02268 204 INTLakGLDIRLNHRVTKIVRRYNGVKVTVEDGTTFVADAAIIAVPlGVLKANiIKFEPELPEWKEEAISDLGVGIENKI 283

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 307 MVYYKEAFWKKKDYCGCMiiedeeAPISIT----LDDTKPDGS-----MPAimgfilARKAERLAKLHKDIRKRKICELY 377
Cdd:PLN02268 284 ALHFDSVFWPNVEFLGVV------APTSYGcsyfLNLHKATGHpvlvyMPA------GRLARDIEKLSDEAAANFAMSQL 351

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 378 AKVLgsQEALSPVHYEEKNWCEEQYSGGCYTAYFPPGIMTLYGRvIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAR 457
Cdd:PLN02268 352 KKML--PDATEPVQYLVSRWGSDPNSLGCYSYDLVGKPHDLYER-LRAPVDNLFFAGEATSSDFPGSVHGAYSTGVMAAE 428


                 .
gi 255759902 458 E 458
Cdd:PLN02268 429 E 429
PLN02676 PLN02676
polyamine oxidase
 14-470 1.06e-18

polyamine oxidase


Pssm-ID: 215362 [Multi-domain]  Cd Length: 487  Bit Score: 89.00  E-value: 1.06e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  14 FDVVVIGGGISGLAAAKLLSEYKI-NVLVLEARDRVGGRTYTVRNEHVKwVDVGGAYV----GPTQNRILRLSKELGIET 88
Cdd:PLN02676  27 PSVIIVGAGMSGISAAKTLSEAGIeDILILEATDRIGGRMRKANFAGVS-VELGANWVegvgGPESNPIWELANKLKLRT 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  89 YKVNV-NERLVQYVK-GKTYPfrgafppvwNPLAYlDYNNLWRTMDDMGKEipVDAPWQARHAEEWDKITMKDLIDKIcw 166
Cdd:PLN02676 106 FYSDFdNLSSNIYKQdGGLYP---------KKVVQ-KSMKVADASDEFGEN--LSISLSAKKAVDISILTAQRLFGQV-- 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 167 TKTAREFAYLFVNINVT-SEPHEVSALwflwyvrqcGGTSRIFSVTNGGQERKFVGGSG-------QISEQIM-----VL 233
Cdd:PLN02676 172 PKTPLEMVIDYYNYDYEfAEPPRVTSL---------KNTEPNPTFVDFGEDEYFVADPRgyeslvyYLAEQFLstksgKI 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 234 LGDKVKLSSPVTYIDQTDDNIIIETLNHEHYECKYVI-SAIPPVL-TAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYK 311
Cdd:PLN02676 243 TDPRLKLNKVVREISYSKNGVTVKTEDGSVYRAKYVIvSVSLGVLqSDLIKFKPPLPDWKIEAIYQFDMAVYTKIFLKFP 322

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 312 EAFWKkkdyCG----CMIIEDEEA---PISITLDDTKPDGSMpaIMGFILARKAERLAKLHKDIRKRKICELYAKVLGSQ 384
Cdd:PLN02676 323 YKFWP----SGpgteFFLYAHERRgyyPFWQHLENEYPGSNV--LFVTVTDEESRRIEQQPDSETKAEIMEVLRKMFGPN 396

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 385 -----EALSPvhyeekNWCEEQYSGGCYTAYfPPGIMTLYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREV 459
Cdd:PLN02676 397 ipeatDILVP------RWWSNRFFKGSYSNW-PIGVSRYEFDQIRAPVGRVYFTGEHTSEKYNGYVHGAYLAGIDTANDL 469

                        490
                 ....*....|.
gi 255759902 460 LNALGKVAKKD 470
Cdd:PLN02676 470 LECIKKKKCRK 480
PRK07233 PRK07233
hypothetical protein; Provisional
 16-308 1.89e-18

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 87.63  E-value: 1.89e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVkWVDVGGAYVGPTQNRILRLSKELGIEtykvnvnE 95
Cdd:PRK07233   2 IAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGLAASFEFGGL-PIERFYHHIFKSDEALLELLDELGLE-------D 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  96 RLV-------QYVKGKTYPFRG-----AFPPVwnPL----------AYLDYNNLWRTMDDMGkeipvdapwqarhAEEWd 153
Cdd:PRK07233  74 KLRwretktgYYVDGKLYPLGTplellRFPHL--SLidkfrlglltLLARRIKDWRALDKVP-------------AEEW- 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 154 kitMKDLIDKICWTKtarefayLFvninvtsEP----------HEVSALWFLWYVRqcggtSRIFSVTNGGQERK--FVG 221
Cdd:PRK07233 138 ---LRRWSGEGVYEV-------FW-------EPlleskfgdyaDDVSAAWLWSRIK-----RRGNRRYSLFGEKLgyLEG 195

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 222 GSGQISEQIMVLL---GDKVKLSSPVTYIDQTDDNIIIETLNHEHYECKYVISAIPPVLTAKIhfKPELPPERNQLIQRL 298
Cdd:PRK07233 196 GFATLIDALAEAIearGGEIRLGTPVTSVVIDGGGVTGVEVDGEEEDFDAVISTAPPPILARL--VPDLPADVLARLRRI 273

                        330
                 ....*....|.
gi 255759902 299 P-MGAVikCMV 308
Cdd:PRK07233 274 DyQGVV--CMV 282
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 13-301 1.92e-18

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 87.98  E-value: 1.92e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  13 MFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTV-RNEHVkwVDVGGAYVGPTQ--NRILRlskELGIETY 89
Cdd:COG1233    3 MYDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTPGGRARTFeRPGFR--FDVGPSVLTMPGvlERLFR---ELGLEDY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  90 kVNVNERLVQYvkgkTYPFRGAfppvwnplAYLDynnLWRTMDDMGKEI----PVDA--------PWQARHAEEWDKI-- 155
Cdd:COG1233   78 -LELVPLDPAY----RVPFPDG--------RALD---LPRDLERTAAELerlfPGDAeayrrflaELRRLYDALLEDLly 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 156 ----TMKDLIDKICW-------TKTAREF------------AYLFVNINVTSEPHEVSAL-WFLWYVRQCGGTSRIfsvt 211
Cdd:COG1233  142 rpllSLRDLLRPLALarllrllLRSLRDLlrryfkdprlraLLAGQALYLGLSPDRTPALyALIAYLEYAGGVWYP---- 217

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 212 nggqerkfVGGSGQISE---QIMVLLGDKVKLSSPVTYIDQTDDNII-IETLNHEHYECKYVISAIPPVLTAKIHFKPE- 286
Cdd:COG1233  218 --------KGGMGALADalaRLAEELGGEIRTGAEVERILVEGGRATgVRLADGEEIRADAVVSNADPAHTYLRLLGEEa 289

                        330
                 ....*....|....*
gi 255759902 287 LPPERNQLIQRLPMG 301
Cdd:COG1233  290 LPARYRRRLERFRYS 304
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
18-84 1.02e-13

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 66.02  E-value: 1.02e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 255759902   18 VIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKwVDVGG-AYVGPTQNRILRLSKEL 84
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNAYSYRVPGYV-FDYGAhIFHGSDEPNVRDLLDEL 67
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 13-467 1.16e-13

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 72.96  E-value: 1.16e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  13 MFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNE----------HVKWvdvgGAYvgptQNrILRLSK 82
Cdd:COG3349    3 PPRVVVVGGGLAGLAAAVELAEAGFRVTLLEARPRLGGRARSFPDPdtglpidngqHVLL----GCY----RN-TLDLLR 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  83 ELGIETYKVNVNERLVQYVKGKTYPFR-GAFPPVWNPLAYL---------DYNNLWRTMddmgkeipvdAPWQARHAEEW 152
Cdd:COG3349   74 RIGAADNLVGPEPLQFPLPGGRRWTLRaPRLPAPLHLLRALlrapglslaDRLALLRLL----------TACRERRWREL 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 153 DKITMKDLIDKICWTKTARE-----FAYLFVNInvtsEPHEVSALWFLWYVRQ---CGGTSRIFSVTNGGQERKFVGGSG 224
Cdd:COG3349  144 DDISVADWLRRHGQSPRLIRrlwepLLLAALNT----PPEQASARLALTVLREtllAGPAASDLLVPRGPLSELFVDPAL 219

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 225 QISEQimvlLGDKVKLSSPVTYIDQTDDNI-IIETLNHEHYECKYVISAIPPVLTAKIhfkpeLPPERN----QLIQRLP 299
Cdd:COG3349  220 AYLEA----RGGEVRLGTRVRALEFDGGRVtGLVLADGETVPADAVVLAVPPEVAARL-----LPELARlpelGLLAPLE 290

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 300 MGAVIKCMVYYKEafWKKKDYCGCMIIEDeeAPISITLDDTKPDGSMPAIMGFILArKAERLAKL-HKDIRKRKICELyA 378
Cdd:COG3349  291 YSPIVNVHLWLDR--PVTLGPPPFAGLVG--STSQWVFDRGAGDGGQGGVLSVVIS-AADRLLDLsREELAAEVWAEL-A 364

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 379 KVLGSQEALSPVHYE---EKnwceeqysggcyTAYF---P------PGIMTlygrvirqPVGRIYFAGTETATQWSGYME 446
Cdd:COG3349  365 ALLPAAREALPVWSRvvrEK------------RATFaatPgsdrlrPGART--------PIPNLFLAGDWTATGLPATME 424

                        490       500
                 ....*....|....*....|.
gi 255759902 447 GAVEAGERAAREVLNALGKVA 467
Cdd:COG3349  425 GAVRSGRRAANAILARLGRPA 445
PLN02328 PLN02328
lysine-specific histone demethylase 1 homolog
 15-469 6.69e-13

lysine-specific histone demethylase 1 homolog


Pssm-ID: 215187 [Multi-domain]  Cd Length: 808  Bit Score: 71.56  E-value: 6.69e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  15 DVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEH---VKWVDVGGAYV-GPTQNRILRLSKELGIETYK 90
Cdd:PLN02328 240 NVVVVGAGLAGLVAARQLLSMGFKVVVLEGRARPGGRVKTMKMKGdgvVAAADLGGSVLtGINGNPLGVLARQLGLPLHK 319

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  91 VnvnerlvqyvkgktypfRGAFPpvwnplAYLDYNNLwrtmddmgkeipVDAPWQARHAEEWDKitmkdLIDKICWTKTA 170
Cdd:PLN02328 320 V-----------------RDICP------LYLPDGKA------------VDAEIDSKIEASFNK-----LLDRVCKLRQA 359

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 171 --REFAYLFVNI-----------NVTSEPHEVSAL-WFLWYVRQCGGT-----SRIFSVTNG----GQERKFVGGSGQI- 226
Cdd:PLN02328 360 miEEVKSVDVNLgtaleafrhvyKVAEDPQERMLLnWHLANLEYANASlmsnlSMAYWDQDDpyemGGDHCFIPGGNDTf 439

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 227 ----SEQIMVLLGdkvklsSPVTYIDQTDDNIIIETLNHEhYECKYVISAIPPVLTAK--IHFKPELPPERNQLIQRLPM 300
Cdd:PLN02328 440 vrelAKDLPIFYE------RTVESIRYGVDGVIVYAGGQE-FHGDMVLCTVPLGVLKKgsIEFYPELPQRKKDAIQRLGY 512

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 301 GAVIKCMVYYKEAFWKKK-DYCGcMIIEDEEAPISITLDDTKPDGS-MPAIMGFILARKAERLAKLHKDIRKRKICELYA 378
Cdd:PLN02328 513 GLLNKVALLFPYNFWGGEiDTFG-HLTEDPSMRGEFFLFYSYSSVSgGPLLIALVAGDAAVKFETLSPVESVKRVLQILR 591

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 379 KVLGSQEAL--SPVHYEEKNWCEEQYSGGCYTaYFPPGIMTLYGRVIRQPV--GRIYFAGTETATQWSGYMEGAVEAGER 454
Cdd:PLN02328 592 GIFHPKGIVvpDPVQAVCTRWGKDCFTYGSYS-YVAVGSSGDDYDILAESVgdGRVFFAGEATNKQYPATMHGAFLSGMR 670

                        490
                 ....*....|....*
gi 255759902 455 AAREVLnalgKVAKK 469
Cdd:PLN02328 671 EAANIL----RVARR 681
proto_IX_ox TIGR00562
protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a ...
 13-298 1.35e-11

protoporphyrinogen oxidase; This enzyme oxidizes protoporphyrinogen IX to protoporphyrin IX, a precursor of heme and chlorophyll. Bacillus subtilis HemY also has coproporphyrinogen III to coproporphyrin III oxidase activity in a heterologous expression system, although the role for this activity in vivo is unclear. This protein is a flavoprotein and has a beta-alpha-beta dinucleotide binding motif near the amino end. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 213540 [Multi-domain]  Cd Length: 462  Bit Score: 66.78  E-value: 1.35e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902   13 MFDVVVIGGGISGLAAA----KLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWvDVGGAYVGPTQNRILRLSKELGIET 88
Cdd:TIGR00562   2 KKHVVIIGGGISGLCAAyyleKEIPELPVELTLVEASDRVGGKIQTVKEDGYLI-ERGPDSFLERKKSAPDLVKDLGLEH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902   89 YKVN--VNERLVQYVKGKTYPfrgaFPPVWNPLAYLDYNNL---------WRTMDDMGKEIPVDAPWQARHAEEW----- 152
Cdd:TIGR00562  81 VLVSdaTGQRYVLVNRGKLMP----VPTKIAPFVKTGLFSLggklragmdFIRPASPGKDESVEEFVRRRFGDEVvenli 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  153 ------------DKITMKDLIDKIcwTKTAREFAYLFVNINVTSEPHEvsalwflwyvrqcGGTSRIFSVTNGGQERKFV 220
Cdd:TIGR00562 157 epllsgiyagdpSKLSLKSTFPKF--YQTEQKHGSLILGMKKTRNLPQ-------------GSGLQLTAKKQGQDFQTLA 221

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 255759902  221 GGSGQISEQIMVLLG-DKVKLSSPVTYIDQTDDNIIIETLNHEHYECKYVISAIPPVLTAKIhfkpeLPPERNQLIQRL 298
Cdd:TIGR00562 222 TGLETLPEEIEKRLKlTKVYKGTKVTKLSHRGSNYTLELDNGVTVETDSVVVTAPHKAAAGL-----LSELSNSASSHL 295
PLN02529 PLN02529
lysine-specific histone demethylase 1
 16-462 3.92e-11

lysine-specific histone demethylase 1


Pssm-ID: 178144 [Multi-domain]  Cd Length: 738  Bit Score: 65.68  E-value: 3.92e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTV---RNEHVKWVDVGGAYV-GPTQNRILRLSKELGIETYKV 91
Cdd:PLN02529 163 VIIVGAGLAGLAAARQLLSFGFKVVVLEGRNRPGGRVYTQkmgRKGQFAAVDLGGSVItGIHANPLGVLARQLSIPLHKV 242

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  92 NVNerlvqyvkgktypfrgafPPVWNPLAYLdynnlwrtmddMGKEIpvDAPWQARHAEEWDKIT-----MKDLIDKICW 166
Cdd:PLN02529 243 RDN------------------CPLYKPDGAL-----------VDKEI--DSNIEFIFNKLLDKVTelrqiMGGFANDISL 291

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 167 TKTAREFAYLFVNINVTSEPHEVSalWFLWYVRQC-GGTSRIFSVTN---------GGQERKFVGGSGQ----ISEQIMV 232
Cdd:PLN02529 292 GSVLERLRQLYGVARSTEERQLLD--WHLANLEYAnAGCLSDLSAAYwdqddpyemGGDHCFLAGGNWRlinaLCEGVPI 369

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 233 LLGDKVKLsspvtyIDQTDDNIIIeTLNHEHYECKYVISAIP-PVLTAK-IHFKPELPPERNQLIQRLPMGAVIKCMVYY 310
Cdd:PLN02529 370 FYGKTVDT------IKYGNDGVEV-IAGSQVFQADMVLCTVPlGVLKKRtIRFEPELPRRKLAAIDRLGFGLLNKVAMVF 442

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 311 KEAFWKKK-DYCGCMiiedEEAPIS------ITLDDTKPDGsmPAIMGFILARKAERLAKLHKDIRKRKICELYAKVLGS 383
Cdd:PLN02529 443 PSVFWGEElDTFGCL----NESSNKrgefflFYGYHTVSGG--PALVALVAGEAAQRFENTDPSTLLHRVLSVLRGIYNP 516

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 384 Q--EALSPVHYEEKNWCEEQYSGGCYTAYFPPGIMTLYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLN 461
Cdd:PLN02529 517 KgiNVPDPIQTICTRWGSDPLSYGSYSHVRVQSSGSDYDILAESVSGRLFFAGEATTRQYPATMHGAFLSGLREASRILH 596


                 .
gi 255759902 462 A 462
Cdd:PLN02529 597 V 597
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 8-53 5.32e-11

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 64.50  E-value: 5.32e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 255759902   8 SITGHMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGG----RTY 53
Cdd:COG2072    1 TAATEHVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGtwrdNRY 50
PLN02576 PLN02576
protoporphyrinogen oxidase
 8-314 9.63e-11

protoporphyrinogen oxidase


Pssm-ID: 215314 [Multi-domain]  Cd Length: 496  Bit Score: 63.88  E-value: 9.63e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902   8 SITGHMFDVVVIGGGISGLAAA-KLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDvggayvGP----TQNRILRLSK 82
Cdd:PLN02576   7 SAAASSKDVAVVGAGVSGLAAAyALASKHGVNVLVTEARDRVGGNITSVSEDGFIWEE------GPnsfqPSDPELTSAV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  83 ELGIETYKVNVNERLVQYV--KGKTYPfrgaFPPvwNPLAYLDYNNL--------------WRTMDDMGKEIPVDApWQA 146
Cdd:PLN02576  81 DSGLRDDLVFPDPQAPRYVvwNGKLRP----LPS--NPIDLPTFDLLsapgkiraglgafgWKRPPPPGREESVGE-FVR 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 147 RH--AEEWDKitmkdLIDKICWTKTArefaylfvninvtSEPHEVS---ALWFLWYVRQCGGtSRIFSVTNGGQERK--- 218
Cdd:PLN02576 154 RHlgDEVFER-----LIDPFVSGVYA-------------GDPSSLSmkaAFPKLWNLEKRGG-SIIGGAIKAIQEAKknp 214

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 219 -------------------FVGGSGQISEQIMVLLG-DKVKLSSPVTYIDQTDD---NIIIETLNHE---HYECkyVISA 272
Cdd:PLN02576 215 kpeprdprlpkpkgqtvgsFRGGLQTLPDALAKRLGkDKVKLNWKVLSLSKNDDggySLTYDTPEGKvnvTAKA--VVMT 292

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 255759902 273 IPPVLTAKIhFKPELPPERNQL--IQRLPMGAVIkcMVYYKEAF 314
Cdd:PLN02576 293 APLYVVSEM-LRPKSPAAADALpeFYYPPVAAVT--TSYPKEAV 333
COG3380 COG3380
Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];
12-70 9.81e-11

Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];


Pssm-ID: 442607 [Multi-domain]  Cd Length: 331  Bit Score: 62.97  E-value: 9.81e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 255759902  12 HMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVkWVDVGGAYV 70
Cdd:COG3380    2 SMPDIAIIGAGIAGLAAARALQDAGHEVTVFEKSRGVGGRMATRRLDGG-RFDHGAQYF 59
PLN03000 PLN03000
amine oxidase
 15-471 1.23e-10

amine oxidase


Pssm-ID: 178578 [Multi-domain]  Cd Length: 881  Bit Score: 64.27  E-value: 1.23e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  15 DVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVR---NEHVKWVDVGGAYV-GPTQNRILRLSKELGIETYK 90
Cdd:PLN03000 186 SVVIVGAGLSGLAAARQLMRFGFKVTVLEGRKRPGGRVYTKKmeaNRVGAAADLGGSVLtGTLGNPLGIIARQLGSSLYK 265

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  91 VNVNERLVQyVKGKtypfrgAFPPVWNPLAYLDYNNLwrtMDDMGK------EIPVDAPWQARhAEEWDKITMKDL---- 160
Cdd:PLN03000 266 VRDKCPLYR-VDGK------PVDPDVDLKVEVAFNQL---LDKASKlrqlmgDVSMDVSLGAA-LETFRQVSGNDVatee 334

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 161 IDKICWTKTAREFAylfvNINVTSephEVS-ALWflwyvrqcggtSRIFSVTNGGQERKFVGGSGQ----ISEQIMVLLG 235
Cdd:PLN03000 335 MGLFNWHLANLEYA----NAGLVS---KLSlAFW-----------DQDDPYDMGGDHCFLPGGNGRlvqaLAENVPILYE 396

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 236 DKVKLsspvtyIDQTDDNIIIeTLNHEHYECKYVISAIP-PVL-TAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEA 313
Cdd:PLN03000 397 KTVQT------IRYGSNGVKV-IAGNQVYEGDMVLCTVPlGVLkNGSIKFVPELPQRKLDCIKRLGFGLLNKVAMLFPYV 469

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 314 FWKKK-DYCGCMIIEDEEAPISITLDDTKPDGSMPAIMGFILARKAERLAKLHKDIRKRKICELYAKVLGSQ--EALSPV 390
Cdd:PLN03000 470 FWSTDlDTFGHLTEDPNYRGEFFLFYSYAPVAGGPLLIALVAGEAAHKFETMPPTDAVTRVLHILRGIYEPQgiNVPDPL 549

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 391 HYEEKNWCEEQYSGGCYTAYFPPGIMTLYGrVIRQPV--GRIYFAGTETATQWSGYMEGAVEAGER-AAREVLNALGKVA 467
Cdd:PLN03000 550 QTVCTRWGGDPFSLGSYSNVAVGASGDDYD-ILAESVgdGRLFFAGEATTRRYPATMHGAFVTGLReAANMAQSAKARGI 628


                 ....
gi 255759902 468 KKDI 471
Cdd:PLN03000 629 RKRI 632
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
13-49 1.85e-08

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 56.69  E-value: 1.85e-08
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 255759902  13 MFDVVVIGGGISGLAAAKLLSEY-KINVLVLEARDRVG 49
Cdd:COG0579    4 MYDVVIIGAGIVGLALARELSRYeDLKVLVLEKEDDVA 41
Ppro0129 COG2907
Predicted flavin-containing amine oxidase [General function prediction only];
18-88 3.31e-08

Predicted flavin-containing amine oxidase [General function prediction only];


Pssm-ID: 442151 [Multi-domain]  Cd Length: 423  Bit Score: 55.89  E-value: 3.31e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  18 VIGGGISGLAAAKLLSEyKINVLVLEARDRVGGRTYTVRnehvkwVDVGGAYVG----------PTQNRILRLSKELGIE 87
Cdd:COG2907    8 VIGSGISGLTAAWLLSR-RHDVTLFEANDRLGGHTHTVD------VDLDGRTVPvdtgfivfneRTYPNLTALFAELGVP 80


                 .
gi 255759902  88 T 88
Cdd:COG2907   81 T 81
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 15-83 3.55e-08

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 55.48  E-value: 3.55e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 255759902   15 DVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTyTVRNehVKWvdVGGAYVGPTQNRILRLSKE 83
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGDDPGSGA-SGRN--AGL--IHPGLRYLEPSELARLALE 64
PRK11883 PRK11883
protoporphyrinogen oxidase; Reviewed
 16-107 3.60e-08

protoporphyrinogen oxidase; Reviewed


Pssm-ID: 237009 [Multi-domain]  Cd Length: 451  Bit Score: 55.63  E-value: 3.60e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  16 VVVIGGGISGLAAAKLLSEYK--INVLVLEARDRVGGRTYTVRNEHVkWVDVGG-AYVGptqnR---ILRLSKELGIEty 89
Cdd:PRK11883   3 VAIIGGGITGLSAAYRLHKKGpdADITLLEASDRLGGKIQTVRKDGF-PIELGPeSFLA----RkpsAPALVKELGLE-- 75

                         90       100
                 ....*....|....*....|....*.
gi 255759902  90 kvnvnERLVQ--------YVKGKTYP 107
Cdd:PRK11883  76 -----DELVAnttgqsyiYVNGKLHP 96
crtI_fam TIGR02734
phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two ...
 16-56 1.35e-07

phytoene desaturase; Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]


Pssm-ID: 274273 [Multi-domain]  Cd Length: 495  Bit Score: 54.21  E-value: 1.35e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 255759902   16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVR 56
Cdd:TIGR02734   1 AVVIGAGFGGLALAIRLAAAGIPVTVVEQRDKPGGRAGVLE 41
PLN02976 PLN02976
amine oxidase
 16-66 2.31e-07

amine oxidase


Pssm-ID: 215527 [Multi-domain]  Cd Length: 1713  Bit Score: 53.72  E-value: 2.31e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 255759902   16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVG 66
Cdd:PLN02976  696 IIVVGAGPAGLTAARHLQRQGFSVTVLEARSRIGGRVYTDRSSLSVPVDLG 746
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 12-55 6.82e-07

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 51.09  E-value: 6.82e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 255759902  12 HMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARD--RVGGRTYTV 55
Cdd:COG0654    2 MRTDVLIVGGGPAGLALALALARAGIRVTVVERAPppRPDGRGIAL 47
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
12-90 1.29e-06

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 50.67  E-value: 1.29e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  12 HMFDVVVIGGGISGLAAAKLLSEYKINVLVLEaRDRVGGRTyTVRNehvkwvdvGG----AYVGPTQNRILRLSKElGIE 87
Cdd:COG0665    1 ATADVVVIGGGIAGLSTAYHLARRGLDVTVLE-RGRPGSGA-SGRN--------AGqlrpGLAALADRALVRLARE-ALD 69


                 ...
gi 255759902  88 TYK 90
Cdd:COG0665   70 LWR 72
PLN02612 PLN02612
phytoene desaturase
 16-97 1.09e-05

phytoene desaturase


Pssm-ID: 215330 [Multi-domain]  Cd Length: 567  Bit Score: 47.91  E-value: 1.09e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVG-----GAYVGpTQNrilrLSKELGIetyk 90
Cdd:PLN02612  96 VVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGGKVAAWKDEDGDWYETGlhiffGAYPN-VQN----LFGELGI---- 166


                 ....*..
gi 255759902  91 vnvNERL 97
Cdd:PLN02612 167 ---NDRL 170
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 12-50 1.69e-05

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 47.14  E-value: 1.69e-05
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 255759902  12 HMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGG 50
Cdd:COG1053    2 HEYDVVVVGSGGAGLRAALEAAEAGLKVLVLEKVPPRGG 40
PRK07208 PRK07208
hypothetical protein; Provisional
 12-67 2.10e-05

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 47.19  E-value: 2.10e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 255759902  12 HMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKwVDVGG 67
Cdd:PRK07208   3 NKKSVVIIGAGPAGLTAAYELLKRGYPVTVLEADPVVGGISRTVTYKGNR-FDIGG 57
PRK12416 PRK12416
protoporphyrinogen oxidase; Provisional
 13-294 4.84e-05

protoporphyrinogen oxidase; Provisional


Pssm-ID: 183516  Cd Length: 463  Bit Score: 45.97  E-value: 4.84e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  13 MFDVVVIGGGISGLAA----AKLLSEYKI--NVLVLEARDRVGGRTYTVRnEHVKWVDVGGAYVGPTQNRILRLSKELGI 86
Cdd:PRK12416   1 MKTVVVIGGGITGLSTmfylEKLKKDYNIdlNLILVEKEEYLGGKIHSVE-EKDFIMESGADSIVARNEHVMPLVKDLNL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902  87 EtykvnvnERLVQYVKGKTYPFRgafppvwnplayldynnlwrtmDDMGKEIPVDA----PWQARHAEEWD------KIT 156
Cdd:PRK12416  80 E-------EEMVYNETGISYIYS----------------------DNTLHPIPSDTifgiPMSVESLFSSTlvstkgKIV 130

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 157 -MKDLIDK-ICWTK--TAREFAYLFVNINV-------------TSEPHEV---SAL-WFLWYVRQCGGTSRIFSVTN--- 212
Cdd:PRK12416 131 aLKDFITKnKEFTKdtSLALFLESFLGKELverqiapvlsgvySGKLNELtmaSTLpYLLDYKNKYGSIIKGFEENKkqf 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255759902 213 -GGQERKFVGGSGQISEQI----MVLLGDKVKLSSPVTYIDQTDDNIIIETLNHEHYECKYVISAIPPVLTAKIHFKPEL 287
Cdd:PRK12416 211 qSAGNKKFVSFKGGLSTIIdrleEVLTETVVKKGAVTTAVSKQGDRYEISFANHESIQADYVVLAAPHDIAETLLQSNEL 290


                 ....*..
gi 255759902 288 PPERNQL 294
Cdd:PRK12416 291 NEQFHTF 297
PTZ00367 PTZ00367
squalene epoxidase; Provisional
 6-46 5.78e-05

squalene epoxidase; Provisional


Pssm-ID: 240384 [Multi-domain]  Cd Length: 567  Bit Score: 45.61  E-value: 5.78e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 255759902   6 KPSITGHMFDVVVIGGGISGLAAAKLLSEYKINVLVLEaRD 46
Cdd:PTZ00367  26 KPARTNYDYDVIIVGGSIAGPVLAKALSKQGRKVLMLE-RD 65
PRK08274 PRK08274
FAD-dependent tricarballylate dehydrogenase TcuA;
10-57 7.42e-05

FAD-dependent tricarballylate dehydrogenase TcuA;


Pssm-ID: 236214 [Multi-domain]  Cd Length: 466  Bit Score: 45.25  E-value: 7.42e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 255759902  10 TGHMFDVVVIGGGISGLAAAKLLSEYKINVLVLEA--RDRVGGRTYTVRN 57
Cdd:PRK08274   1 MASMVDVLVIGGGNAALCAALAAREAGASVLLLEAapREWRGGNSRHTRN 50
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
12-48 9.37e-05

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 44.90  E-value: 9.37e-05
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 255759902  12 HMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRV 48
Cdd:PRK06183   9 HDTDVVIVGAGPVGLTLANLLGQYGVRVLVLERWPTL 45
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 12-50 1.01e-04

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 44.69  E-value: 1.01e-04
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 255759902  12 HMFDVVVIGGGISGLAAAKLLSEYKINVLVLEaRDRVGG 50
Cdd:COG1249    2 KDYDLVVIGAGPGGYVAAIRAAQLGLKVALVE-KGRLGG 39
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
14-51 1.78e-04

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 43.57  E-value: 1.78e-04
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 255759902  14 FDVVVIGGGISGLAAAKLLSEYKINVLVLEaRDRVGGR 51
Cdd:COG0492    1 YDVVIIGAGPAGLTAAIYAARAGLKTLVIE-GGEPGGQ 37
MurD COG0771
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; ...
 16-63 2.99e-04

UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramoylalanine-D-glutamate ligase is part of the Pathway/BioSystem: Mureine biosynthesis


Pssm-ID: 440534 [Multi-domain]  Cd Length: 445  Bit Score: 43.15  E-value: 2.99e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 255759902  16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWV 63
Cdd:COG0771    7 VLVLGLGKSGLAAARLLAKLGAEVTVSDDRPAPELAAAELEAPGVEVV 54
PLN02568 PLN02568
polyamine oxidase
 16-54 3.02e-04

polyamine oxidase


Pssm-ID: 215308 [Multi-domain]  Cd Length: 539  Bit Score: 43.28  E-value: 3.02e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 255759902  16 VVVIGGGISGLAAA-KLLSEYKIN----VLVLEARDRVGGRTYT 54
Cdd:PLN02568   8 IVIIGAGMAGLTAAnKLYTSSAANdmfeLTVVEGGDRIGGRINT 51
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
 13-76 3.08e-04

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 43.28  E-value: 3.08e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 255759902  13 MFDVVVIGGGISGLAAAKLLSEY-KINVLVLEArdrvGGRTytvRNEhvkWVDVGGAYVGPTQNR 76
Cdd:COG2303    4 EYDYVIVGAGSAGCVLANRLSEDaGLRVLLLEA----GGRD---DDP---LIRMPAGYAKLLGNP 58
NadB COG0029
Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the ...
 12-42 3.21e-04

Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the Pathway/BioSystem: NAD biosynthesis


Pssm-ID: 439800 [Multi-domain]  Cd Length: 521  Bit Score: 43.17  E-value: 3.21e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 255759902  12 HMFDVVVIGGGISGLAAAKLLSEYKiNVLVL 42
Cdd:COG0029    3 LKTDVLVIGSGIAGLSAALKLAERG-RVTLL 32
PRK12843 PRK12843
FAD-dependent oxidoreductase;
14-54 7.40e-04

FAD-dependent oxidoreductase;


Pssm-ID: 237225 [Multi-domain]  Cd Length: 578  Bit Score: 42.03  E-value: 7.40e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 255759902  14 FDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYT 54
Cdd:PRK12843  17 FDVIVIGAGAAGMSAALFAAIAGLKVLLVERTEYVGGTTAT 57
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
15-51 1.26e-03

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 41.38  E-value: 1.26e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 255759902  15 DVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGR 51
Cdd:COG1148  142 RALVIGGGIAGMTAALELAEQGYEVYLVEKEPELGGR 178
FAD_oxidored pfam12831
FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases ...
 15-50 1.31e-03

FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases and related proteins.


Pssm-ID: 432816 [Multi-domain]  Cd Length: 420  Bit Score: 41.06  E-value: 1.31e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 255759902   15 DVVVIGGGISGLAAAkllseykI-------NVLVLEARDRVGG 50
Cdd:pfam12831   1 DVVVVGGGPAGVAAA-------IaaaragaKVLLVERRGFLGG 36
PRK08132 PRK08132
FAD-dependent oxidoreductase; Provisional
 16-49 1.50e-03

FAD-dependent oxidoreductase; Provisional


Pssm-ID: 236158 [Multi-domain]  Cd Length: 547  Bit Score: 41.01  E-value: 1.50e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 255759902  16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVG 49
Cdd:PRK08132  26 VVVVGAGPVGLALAIDLAQQGVPVVLLDDDDTLS 59
HI0933_like pfam03486
HI0933-like protein;
14-49 1.51e-03

HI0933-like protein;


Pssm-ID: 427330 [Multi-domain]  Cd Length: 406  Bit Score: 41.03  E-value: 1.51e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 255759902   14 FDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVG 49
Cdd:pfam03486   1 FDVIVIGGGAAGLMAAISAAKRGRRVLLIEKGKKLG 36
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 16-50 2.49e-03

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 40.55  E-value: 2.49e-03
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 255759902  16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGG 50
Cdd:PRK11749 143 VAVIGAGPAGLTAAHRLARKGYDVTIFEARDKAGG 177
PRK06847 PRK06847
hypothetical protein; Provisional
 15-86 2.61e-03

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 40.24  E-value: 2.61e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 255759902  15 DVVVIGGGISGLAAAKLLSEYKINVLVLEARDrvggrtytvrnehvKWvDVGGAyvGPT-QNRILRLSKELGI 86
Cdd:PRK06847   6 KVLIVGGGIGGLSAAIALRRAGIAVDLVEIDP--------------EW-RVYGA--GITlQGNALRALRELGV 61
PRK05329 PRK05329
glycerol-3-phosphate dehydrogenase subunit GlpB;
13-42 2.76e-03

glycerol-3-phosphate dehydrogenase subunit GlpB;


Pssm-ID: 235412  Cd Length: 422  Bit Score: 40.22  E-value: 2.76e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 255759902  13 MFDVVVIGGGISGLAAAKLLSEYKINVLVL 42
Cdd:PRK05329   2 KFDVLVIGGGLAGLTAALAAAEAGKRVALV 31
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 14-51 3.50e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 39.61  E-value: 3.50e-03
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 255759902   14 FDVVVIGGGISGLAAAKLLSEYKINVLVLEA-RDRVGGR 51
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIEDeGTCPYGG 39
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 15-52 3.52e-03

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 39.96  E-value: 3.52e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 255759902   15 DVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRT 52
Cdd:pfam00890   1 DVLVIGGGLAGLAAALAAAEAGLKVAVVEKGQPFGGAT 38
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 14-49 4.13e-03

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 39.22  E-value: 4.13e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 255759902   14 FDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVG 49
Cdd:TIGR02032   1 YDVVVVGAGPAGASAAYRLADKGLRVLLLEKKSFPR 36
PRK11728 PRK11728
L-2-hydroxyglutarate oxidase;
13-49 4.45e-03

L-2-hydroxyglutarate oxidase;


Pssm-ID: 183292 [Multi-domain]  Cd Length: 393  Bit Score: 39.42  E-value: 4.45e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 255759902  13 MFDVVVIGGGISGLAAAK-LLSEY-KINVLVLEARDRVG 49
Cdd:PRK11728   2 MYDFVIIGGGIVGLSTAMqLQERYpGARIAVLEKESGPA 40
AlaDh_PNT_C smart01002
Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the ...
 16-70 4.57e-03

Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase catalyzes the NAD-dependent reversible reductive amination of pyruvate into alanine.


Pssm-ID: 214966 [Multi-domain]  Cd Length: 149  Bit Score: 37.87  E-value: 4.57e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 255759902    16 VVVIGGGISGLAAAKLLSEYKINVLVL--------EARDRVGGRTYTVR------NEHVKWVD--VGGAYV 70
Cdd:smart01002  23 VVVIGAGVVGLGAAATAKGLGAEVTVLdvrparlrQLESLLGARFTTLYsqaellEEAVKEADlvIGAVLI 93
PRK08163 PRK08163
3-hydroxybenzoate 6-monooxygenase;
16-49 7.66e-03

3-hydroxybenzoate 6-monooxygenase;


Pssm-ID: 181262 [Multi-domain]  Cd Length: 396  Bit Score: 38.86  E-value: 7.66e-03
                         10        20        30
                 ....*....|....*....|....*....|....
gi 255759902  16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRVG 49
Cdd:PRK08163   7 VLIVGGGIGGLAAALALARQGIKVKLLEQAAEIG 40
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
21-51 7.71e-03

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 38.41  E-value: 7.71e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 255759902  21 GGISGLAAAKLLSEYKINVLVLEARDRVGGR 51
Cdd:COG0644    1 AGPAGSAAARRLARAGLSVLLLEKGSFPGDK 31
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 16-48 8.36e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 35.26  E-value: 8.36e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 255759902   16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRV 48
Cdd:pfam00070   2 VVVVGGGYIGLELAGALARLGSKVTVVERRDRL 34
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 16-48 8.39e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 38.45  E-value: 8.39e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 255759902   16 VVVIGGGISGLAAAKLLSEYKINVLVLEARDRV 48
Cdd:pfam07992 155 VVVVGGGYIGVELAAALAKLGKEVTLIEALDRL 187
GlpB COG3075
Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism];
14-29 9.53e-03

Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism];


Pssm-ID: 442309  Cd Length: 415  Bit Score: 38.62  E-value: 9.53e-03
                         10
                 ....*....|....*.
gi 255759902  14 FDVVVIGGGISGLAAA 29
Cdd:COG3075    3 FDVVVIGGGLAGLTAA 18
PRK07364 PRK07364
FAD-dependent hydroxylase;
7-45 9.62e-03

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 38.46  E-value: 9.62e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 255759902   7 PSITGHMFDVVVIGGGISGLAAAKLLSEYKINVLVLEAR 45
Cdd:PRK07364  12 PSTRSLTYDVAIVGGGIVGLTLAAALKDSGLRIALIEAQ 50
PRK05249 PRK05249
Si-specific NAD(P)(+) transhydrogenase;
14-50 9.82e-03

Si-specific NAD(P)(+) transhydrogenase;


Pssm-ID: 235373 [Multi-domain]  Cd Length: 461  Bit Score: 38.60  E-value: 9.82e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 255759902  14 FDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGG 50
Cdd:PRK05249   6 YDLVVIGSGPAGEGAAMQAAKLGKRVAVIERYRNVGG 42
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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