|
Name |
Accession |
Description |
Interval |
E-value |
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
33-453 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 682.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 33 VLLGAQWGDEGKGKIIDYLIEnhKINVTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFFSE 112
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAE--DADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 113 LAHngiLEESG--WEKRIMISSEAHLVFGVHSQVDGRQEDSLAaKNKIGTTNRGIGPTYSSKCFRNGIRVADLMaDFEEF 190
Cdd:pfam00709 79 IEE---LEERGidVPDRLFISDRAHLILPYHKALDGLREEARG-KKKIGTTGRGIGPAYSDKAARRGIRVGDLL-DPEVF 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 191 SEKYRRLVEHYKKQFPSI---EVNVDEELAKFKQHREKLAelKLVGDTVGFIHEQRNAGKQVLVEGANGALLDIDFGTYP 267
Cdd:pfam00709 154 REKLEALLELKNKLLEKLygePLDVEEELEELLEYAERLK--PYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYP 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 268 YVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLFLLR 347
Cdd:pfam00709 232 YVTSSNTTAGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALR 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 348 RSAMINGYTAIALTKLDILDTFPTIKVAVGYKLNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDLPEKCRQ 427
Cdd:pfam00709 312 YAVRINGVTGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARK 391
|
410 420
....*....|....*....|....*.
gi 25146553 428 YVKFIEDFIKVPIVYIGVGAERESLI 453
Cdd:pfam00709 392 YVEFIEELLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
31-454 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 636.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 31 VSVLLGAQWGDEGKGKIIDYLIEnhKINVTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFF 110
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAE--KADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 111 SELAHngiLEESG--WEKRIMISSEAHLVFGVHSQVDGRQEdslaaKNKIGTTNRGIGPTYSSKCFRNGIRVADLMaDFE 188
Cdd:smart00788 79 KEIEE---LEAKGvdVKDRLFISDRAHLILPYHIALDKARE-----KARIGTTGRGIGPAYEDKVARRGIRVGDLF-DEE 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 189 EFSEKYRRLVEHYKKQFPSI----EVNVDEELAKFKQHREKLAelKLVGDTVGFIHEQRNAGKQVLVEGANGALLDIDFG 264
Cdd:smart00788 150 VLREKLEELLDYKNFLLKKLygaePVDVEEILEELLEYAERLR--PYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHG 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 265 TYPYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLF 344
Cdd:smart00788 228 TYPYVTSSNTTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAV 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 345 LLRRSAMINGYTAIALTKLDILDTFPTIKVAVGYKLNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDLPEK 424
Cdd:smart00788 308 LLRYAVRINGITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPEN 387
|
410 420 430
....*....|....*....|....*....|
gi 25146553 425 CRQYVKFIEDFIKVPIVYIGVGAERESLIV 454
Cdd:smart00788 388 AKKYIERIEELVGVPVSIISTGPDREQTIV 417
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
31-456 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 615.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 31 VSVLLGAQWGDEGKGKIIDYLIENHkiNVTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFF 110
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERA--DVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 111 SELAHngiLEESG--WEKRIMISSEAHLVFGVHSQVDGRQEDSLAaKNKIGTTNRGIGPTYSSKCFRNGIRVADLMaDFE 188
Cdd:COG0104 79 EEIDG---LEARGvdVRSRLRISERAHLILPYHRALDKAREEARG-KKKIGTTGRGIGPAYEDKVARRGIRVGDLL-DPE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 189 EFSEKYRRLVEHYKKQFPSI----EVNVDEELAKFKQHREKLAelKLVGDTVGFIHEQRNAGKQVLVEGANGALLDIDFG 264
Cdd:COG0104 154 VLREKLEELLEYKNFLLEKLygaePLDFEELLEEYLEYAERLK--PYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHG 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 265 TYPYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLF 344
Cdd:COG0104 232 TYPYVTSSNTTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 345 LLRRSAMINGYTAIALTKLDILDTFPTIKVAVGYKLNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDLPEK 424
Cdd:COG0104 312 ALRYAVRINGLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPEN 391
|
410 420 430
....*....|....*....|....*....|..
gi 25146553 425 CRQYVKFIEDFIKVPIVYIGVGAERESLIVRQ 456
Cdd:COG0104 392 ARAYVERIEELLGVPISIVSVGPDREQTIVRR 423
|
|
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
33-456 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 593.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 33 VLLGAQWGDEGKGKIIDYLIENhkINVTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFFSE 112
Cdd:PRK01117 5 VVVGTQWGDEGKGKIVDLLSER--ADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALLKE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 113 LAHngiLEESGWE--KRIMISSEAHLVFGVHSQVDGRQEDSLAaKNKIGTTNRGIGPTYSSKCFRNGIRVADLMaDFEEF 190
Cdd:PRK01117 83 IDE---LEARGVDvrERLRISERAHLILPYHRALDKAREKARG-KKKIGTTGRGIGPAYEDKVARRGIRVGDLL-DPETF 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 191 SEKYRRLVEHYKKQFPSI----EVNVDEELAKFKQHREKLaeLKLVGDTVGFIHEQRNAGKQVLVEGANGALLDIDFGTY 266
Cdd:PRK01117 158 AEKLEENLEYKNFLLTKYygaeAVDFEEILDEYLEYAERL--KPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTY 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 267 PYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLFLL 346
Cdd:PRK01117 236 PFVTSSNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVAL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 347 RRSAMINGYTAIALTKLDILDTFPTIKVAVGYKLNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDLPEKCR 426
Cdd:PRK01117 316 RYAVRVNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENAR 395
|
410 420 430
....*....|....*....|....*....|
gi 25146553 427 QYVKFIEDFIKVPIVYIGVGAERESLIVRQ 456
Cdd:PRK01117 396 KYIKRIEELTGVPISIISTGPDRDQTIILR 425
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
33-454 |
6.25e-173 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 491.68 E-value: 6.25e-173
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 33 VLLGAQWGDEGKGKIIDYLIENHKInvTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFFSE 112
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDI--VARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 113 LAHngiLEESGW--EKRIMISSEAHLVFGVHSQVDGRQEDSLAAKNkIGTTNRGIGPTYSSKCFRNGIRVADLMAD---F 187
Cdd:TIGR00184 79 MEY---LEKRGIsvRDRLFVSYRCHLILPYHKKLDKAREKSKLAKK-IGTTGKGIGPAYEDKVARSGLRVGDLLDDeafA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 188 EEFSEKYRRLVEHYKKQFPSIEVNVDEELAKFKQHREKLAelKLVGDTVGFIHEQRNAGKQVLVEGANGALLDIDFGTYP 267
Cdd:TIGR00184 155 EKAKNILEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELK--PFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 268 YVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLFLLR 347
Cdd:TIGR00184 233 YVTSSNTTAGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAAR 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 348 RSAMINGYTAIALTKLDILDTFPTIKVAVGYKLNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDLPEKCRQ 427
Cdd:TIGR00184 313 YACRLNGATQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKK 392
|
410 420
....*....|....*....|....*..
gi 25146553 428 YVKFIEDFIKVPIVYIGVGAERESLIV 454
Cdd:TIGR00184 393 YIERIEELTGVPVTIISTGPEREQTID 419
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
31-454 |
9.41e-172 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 484.31 E-value: 9.41e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 31 VSVLLGAQWGDEGKGKIIDYLIEnhKINVTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFF 110
Cdd:cd03108 2 VTVVVGAQWGDEGKGKIVDYLAE--KADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 111 SELAhngILEESG--WEKRIMISSEAHLVFGVHSQVDGRQEDSLAaKNKIGTTNRGIGPTYSSKCFRNGIRVADlmadfe 188
Cdd:cd03108 80 EEIE---ELEKKGidVKGRLLISDRAHLVFPYHQELDGLEEKERG-GKKIGTTKRGIGPAYADKAARTGIRVGD------ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 189 efsekyrrlvehykkqfpsievnvdeelakfkqhreklaelKLVGDTVGFIHEQRNAGKQVLVEGANGALLDIDFGTYPY 268
Cdd:cd03108 150 -----------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPY 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 269 VTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLFLLRR 348
Cdd:cd03108 189 VTSSNTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRY 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 349 SAMINGYTAIALTKLDIldtfptikvavgyklngqvlssppaqanawgaieveykefegwneptvgvrkfedlpeKCRQY 428
Cdd:cd03108 269 AVRINGLTELALTKLDV----------------------------------------------------------NAQKY 290
|
410 420
....*....|....*....|....*.
gi 25146553 429 VKFIEDFIKVPIVYIGVGAERESLIV 454
Cdd:cd03108 291 IERIEELLGVPITYISVGPDREQTII 316
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
31-354 |
1.37e-27 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 111.31 E-value: 1.37e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 31 VSVLLGAQWGDEGKGKIIDYLIE--NHKINVTArcqGGNNAGHTVV-ANGRKYDFHILPSGIISPTCFNV-IGNGVVVNL 106
Cdd:NF038379 1 VDVVVDGQFGSTGKGLIAGYLAEraAPDVVVRA---AGPNAGHTYIdDEGRKFVHRMLPNGIVSPPLKQVlIGPGSEIDL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 107 DAFFSE-LAHNGILEESGweKRIMISSEAHLVFGvHSQVDgrQEDSLAAknKIGTTNRGIGPTYSSKCFRNGIRVADLMA 185
Cdd:NF038379 78 EVLREEiEELEDAGHDVG--KRLLIHEQATVIEL-HKHVE--EEAGPMT--KIGSTKKGIGAARAAKIRRNPSTLGDAEG 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 186 DFEEFSEKYRRLVEHykkqfpsiEVNVDEELAKFKQHReklaelklvgdtvgfiheqrnaGKQVLVEGANGALLDIDFGT 265
Cdd:NF038379 151 DFGEGAVRDQPWEIA--------ERVVDNALYDFALQA----------------------AERIQIEGTQGYSLGLHAGF 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 266 YPYVTSSNSTVGGACTGIGVPPTAV--GNVIGVVKAYQTRVGT-----GPFPTEL-FDSDG--EKLQTIGKEVgvttgrk 335
Cdd:NF038379 201 YPYCTSRDCTPADFLADAGIPLPNVdaFKVVGTARTYPIRVAGwsgnsYPDQGETtWEELGlpEELTTVTKKV------- 273
|
330
....*....|....*....
gi 25146553 336 RRCGWIDLFLLRRSAMING 354
Cdd:NF038379 274 RRVGTFSAEQVREAVQANG 292
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
33-453 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 682.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 33 VLLGAQWGDEGKGKIIDYLIEnhKINVTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFFSE 112
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAE--DADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 113 LAHngiLEESG--WEKRIMISSEAHLVFGVHSQVDGRQEDSLAaKNKIGTTNRGIGPTYSSKCFRNGIRVADLMaDFEEF 190
Cdd:pfam00709 79 IEE---LEERGidVPDRLFISDRAHLILPYHKALDGLREEARG-KKKIGTTGRGIGPAYSDKAARRGIRVGDLL-DPEVF 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 191 SEKYRRLVEHYKKQFPSI---EVNVDEELAKFKQHREKLAelKLVGDTVGFIHEQRNAGKQVLVEGANGALLDIDFGTYP 267
Cdd:pfam00709 154 REKLEALLELKNKLLEKLygePLDVEEELEELLEYAERLK--PYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYP 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 268 YVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLFLLR 347
Cdd:pfam00709 232 YVTSSNTTAGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALR 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 348 RSAMINGYTAIALTKLDILDTFPTIKVAVGYKLNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDLPEKCRQ 427
Cdd:pfam00709 312 YAVRINGVTGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARK 391
|
410 420
....*....|....*....|....*.
gi 25146553 428 YVKFIEDFIKVPIVYIGVGAERESLI 453
Cdd:pfam00709 392 YVEFIEELLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
31-454 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 636.83 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 31 VSVLLGAQWGDEGKGKIIDYLIEnhKINVTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFF 110
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAE--KADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 111 SELAHngiLEESG--WEKRIMISSEAHLVFGVHSQVDGRQEdslaaKNKIGTTNRGIGPTYSSKCFRNGIRVADLMaDFE 188
Cdd:smart00788 79 KEIEE---LEAKGvdVKDRLFISDRAHLILPYHIALDKARE-----KARIGTTGRGIGPAYEDKVARRGIRVGDLF-DEE 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 189 EFSEKYRRLVEHYKKQFPSI----EVNVDEELAKFKQHREKLAelKLVGDTVGFIHEQRNAGKQVLVEGANGALLDIDFG 264
Cdd:smart00788 150 VLREKLEELLDYKNFLLKKLygaePVDVEEILEELLEYAERLR--PYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHG 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 265 TYPYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLF 344
Cdd:smart00788 228 TYPYVTSSNTTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAV 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 345 LLRRSAMINGYTAIALTKLDILDTFPTIKVAVGYKLNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDLPEK 424
Cdd:smart00788 308 LLRYAVRINGITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPEN 387
|
410 420 430
....*....|....*....|....*....|
gi 25146553 425 CRQYVKFIEDFIKVPIVYIGVGAERESLIV 454
Cdd:smart00788 388 AKKYIERIEELVGVPVSIISTGPDREQTIV 417
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
31-456 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 615.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 31 VSVLLGAQWGDEGKGKIIDYLIENHkiNVTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFF 110
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERA--DVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 111 SELAHngiLEESG--WEKRIMISSEAHLVFGVHSQVDGRQEDSLAaKNKIGTTNRGIGPTYSSKCFRNGIRVADLMaDFE 188
Cdd:COG0104 79 EEIDG---LEARGvdVRSRLRISERAHLILPYHRALDKAREEARG-KKKIGTTGRGIGPAYEDKVARRGIRVGDLL-DPE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 189 EFSEKYRRLVEHYKKQFPSI----EVNVDEELAKFKQHREKLAelKLVGDTVGFIHEQRNAGKQVLVEGANGALLDIDFG 264
Cdd:COG0104 154 VLREKLEELLEYKNFLLEKLygaePLDFEELLEEYLEYAERLK--PYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHG 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 265 TYPYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLF 344
Cdd:COG0104 232 TYPYVTSSNTTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 345 LLRRSAMINGYTAIALTKLDILDTFPTIKVAVGYKLNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDLPEK 424
Cdd:COG0104 312 ALRYAVRINGLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPEN 391
|
410 420 430
....*....|....*....|....*....|..
gi 25146553 425 CRQYVKFIEDFIKVPIVYIGVGAERESLIVRQ 456
Cdd:COG0104 392 ARAYVERIEELLGVPISIVSVGPDREQTIVRR 423
|
|
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
33-456 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 593.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 33 VLLGAQWGDEGKGKIIDYLIENhkINVTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFFSE 112
Cdd:PRK01117 5 VVVGTQWGDEGKGKIVDLLSER--ADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALLKE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 113 LAHngiLEESGWE--KRIMISSEAHLVFGVHSQVDGRQEDSLAaKNKIGTTNRGIGPTYSSKCFRNGIRVADLMaDFEEF 190
Cdd:PRK01117 83 IDE---LEARGVDvrERLRISERAHLILPYHRALDKAREKARG-KKKIGTTGRGIGPAYEDKVARRGIRVGDLL-DPETF 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 191 SEKYRRLVEHYKKQFPSI----EVNVDEELAKFKQHREKLaeLKLVGDTVGFIHEQRNAGKQVLVEGANGALLDIDFGTY 266
Cdd:PRK01117 158 AEKLEENLEYKNFLLTKYygaeAVDFEEILDEYLEYAERL--KPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTY 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 267 PYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLFLL 346
Cdd:PRK01117 236 PFVTSSNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVAL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 347 RRSAMINGYTAIALTKLDILDTFPTIKVAVGYKLNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDLPEKCR 426
Cdd:PRK01117 316 RYAVRVNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENAR 395
|
410 420 430
....*....|....*....|....*....|
gi 25146553 427 QYVKFIEDFIKVPIVYIGVGAERESLIVRQ 456
Cdd:PRK01117 396 KYIKRIEELTGVPISIISTGPDRDQTIILR 425
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
31-456 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 572.74 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 31 VSVLLGAQWGDEGKGKIIDYLIENHkiNVTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFF 110
Cdd:PTZ00350 14 VVVILGAQWGDEGKGKLVDILSEKA--DIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSLL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 111 SELAhngILEESGWE--KRIMISSEAHLVFGVHSQVDGRQEDSLAAKNK-IGTTNRGIGPTYSSKCFRNGIRVADLMaDF 187
Cdd:PTZ00350 92 EEIE---QLTKKGINllGRLYISDRAHLVFDLHQAIDGIQESEKGKGGTqIGTTKRGIGPCYSTKASRTGLRVGDLL-NF 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 188 EEFSEKYRRLVEHYKKQFPSIEVNVDEELAKFKQHREKLAelKLVGDTVGFIHEQRNAGKQVLVEGANGALLDIDFGTYP 267
Cdd:PTZ00350 168 ETFEKKYRKLVEKLQEQYNIEEYDAEEELERYKGYAEKLK--DMIVDTVYFMNKAIKEGKRVLVEGANATMLDIDFGTYP 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 268 YVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLFLLR 347
Cdd:PTZ00350 246 YVTSSNTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALR 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 348 RSAMINGYTAIALTKLDILDTFPTIKVAVGYKLNGQVLS--SPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDLPEKC 425
Cdd:PTZ00350 326 YVQMINGFDSINLTKLDVLSGLKEIKICVNYKNKGTGLEigRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENA 405
|
410 420 430
....*....|....*....|....*....|.
gi 25146553 426 RQYVKFIEDFIKVPIVYIGVGAERESLIVRQ 456
Cdd:PTZ00350 406 QKYVLFIEELLGVPIVWIGVGPNRENMIVKK 436
|
|
| PLN02513 |
PLN02513 |
adenylosuccinate synthase |
31-456 |
0e+00 |
|
adenylosuccinate synthase
Pssm-ID: 178129 Cd Length: 427 Bit Score: 525.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 31 VSVLLGAQWGDEGKGKIIDYLIENHKInvTARCQGGNNAGHTVV-ANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAF 109
Cdd:PLN02513 4 VSAVLGTQWGDEGKGKLVDILAQHFDI--VARCQGGANAGHTIYnDEGKKFALHLVPSGILNEKTTCVIGNGVVVHLPGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 110 FSELahnGILEESG--WEKRIMISSEAHLVFGVHSQVDGRQEDSLAaKNKIGTTNRGIGPTYSSKCFRNGIRVADLMaDF 187
Cdd:PLN02513 82 FEEI---DGLESNGvsCEGRLLVSDRAHLLFDFHQEVDGLREAELA-GSKIGTTKRGIGPAYSSKATRNGLRVGDLR-HM 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 188 EEFSEKYRRLVEHYKKQFPSIE---VNVDEELAKFKQHREKLaeLKLVGDTVGFIHEQRNAGKQVLVEGANGALLDIDFG 264
Cdd:PLN02513 157 DTFAEKLRELLADAAARFEGFEydaSMVEEEVEAYKKFAERL--EPFITDTVHYLNEAIQAGKKILVEGAQATMLDIDFG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 265 TYPYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLF 344
Cdd:PLN02513 235 TYPFVTSSNPSAGGICTGLGIAPRKLGDIIGVVKAYTTRVGSGPFPTELFGELGDLLREAGQEFGTTTGRPRRCGWLDIV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 345 LLRRSAMINGYTAIALTKLDILDTFPTIKVAVGYKL-NGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDLPE 423
Cdd:PLN02513 315 ALKYSCQINGFTSLNLTKLDVLSGLPEIKIGVAYKTpDGKVVKSFPADLDTLEQVEVVYEVLPGWQEDISSVRNYDDLPA 394
|
410 420 430
....*....|....*....|....*....|...
gi 25146553 424 KCRQYVKFIEDFIKVPIVYIGVGAERESLIVRQ 456
Cdd:PLN02513 395 AAQAYVERIEELVGVPVHYIGVGPGRDALIVKP 427
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
33-454 |
6.25e-173 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 491.68 E-value: 6.25e-173
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 33 VLLGAQWGDEGKGKIIDYLIENHKInvTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFFSE 112
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDI--VARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 113 LAHngiLEESGW--EKRIMISSEAHLVFGVHSQVDGRQEDSLAAKNkIGTTNRGIGPTYSSKCFRNGIRVADLMAD---F 187
Cdd:TIGR00184 79 MEY---LEKRGIsvRDRLFVSYRCHLILPYHKKLDKAREKSKLAKK-IGTTGKGIGPAYEDKVARSGLRVGDLLDDeafA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 188 EEFSEKYRRLVEHYKKQFPSIEVNVDEELAKFKQHREKLAelKLVGDTVGFIHEQRNAGKQVLVEGANGALLDIDFGTYP 267
Cdd:TIGR00184 155 EKAKNILEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELK--PFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 268 YVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLFLLR 347
Cdd:TIGR00184 233 YVTSSNTTAGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAAR 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 348 RSAMINGYTAIALTKLDILDTFPTIKVAVGYKLNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFEDLPEKCRQ 427
Cdd:TIGR00184 313 YACRLNGATQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKK 392
|
410 420
....*....|....*....|....*..
gi 25146553 428 YVKFIEDFIKVPIVYIGVGAERESLIV 454
Cdd:TIGR00184 393 YIERIEELTGVPVTIISTGPEREQTID 419
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
31-454 |
9.41e-172 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 484.31 E-value: 9.41e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 31 VSVLLGAQWGDEGKGKIIDYLIEnhKINVTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFF 110
Cdd:cd03108 2 VTVVVGAQWGDEGKGKIVDYLAE--KADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 111 SELAhngILEESG--WEKRIMISSEAHLVFGVHSQVDGRQEDSLAaKNKIGTTNRGIGPTYSSKCFRNGIRVADlmadfe 188
Cdd:cd03108 80 EEIE---ELEKKGidVKGRLLISDRAHLVFPYHQELDGLEEKERG-GKKIGTTKRGIGPAYADKAARTGIRVGD------ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 189 efsekyrrlvehykkqfpsievnvdeelakfkqhreklaelKLVGDTVGFIHEQRNAGKQVLVEGANGALLDIDFGTYPY 268
Cdd:cd03108 150 -----------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPY 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 269 VTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLFLLRR 348
Cdd:cd03108 189 VTSSNTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRY 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 349 SAMINGYTAIALTKLDIldtfptikvavgyklngqvlssppaqanawgaieveykefegwneptvgvrkfedlpeKCRQY 428
Cdd:cd03108 269 AVRINGLTELALTKLDV----------------------------------------------------------NAQKY 290
|
410 420
....*....|....*....|....*.
gi 25146553 429 VKFIEDFIKVPIVYIGVGAERESLIV 454
Cdd:cd03108 291 IERIEELLGVPITYISVGPDREQTII 316
|
|
| PRK13787 |
PRK13787 |
adenylosuccinate synthetase; Provisional |
32-454 |
2.74e-126 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172324 Cd Length: 423 Bit Score: 373.13 E-value: 2.74e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 32 SVLLGAQWGDEGKGKIIDYLIENHKINVtaRCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFFS 111
Cdd:PRK13787 4 SLVVGTQWGDEGKAKVIDFLSKDTDIIV--RYQGGANAGHTVVVHGKKYVFHLVPSGVIYDQTICVIGNGVVLDPLFFIE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 112 ELAHngiLEESGW--EKRIMISSEAHLVFGVHSQVDGRQEDSLAAKNKIGTTNRGIGPTYSSKCFRNGIRVADLMADFEE 189
Cdd:PRK13787 82 ECDR---LQKEGFpvKDKLLLSDACHLLFPYHSQIDSARETTSSQEHKIGTTKKGIGICYADKMMRTGLRVGDLLDKSYK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 190 ------FSEKYRRLVEHYKKQfpsiEVNVDEELAKFKQHREKLAelKLVGDTVGFIHEQRNAGKQVLVEGANGALLDIDF 263
Cdd:PRK13787 159 rrlkhlVDEKNRELDKLYGMP----PVSYNDINDGLKFFLSKVG--KNIINTAYYLDTELKKGKRVLLEGAQGTGLDVDF 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 264 GTYPYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDL 343
Cdd:PRK13787 233 GTYPYVTSSNPTTGGALIGTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEVLRQKGGEFGATTGRPRRCGWFDV 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 344 FLLRRSAMINGYTAIALTKLDILDTFPTIKVAVGYKLNGQVLSSPPAQanAWGAIEVEYKEFEGWNEPTVGVRKFEDLPE 423
Cdd:PRK13787 313 EMLKHSVRINGITSIALTKIDILSDYDTIPVAVGYKLNGKTLDCFPSQ--GLEKVEPLYEEFPGWKDDISGINEFQKLPE 390
|
410 420 430
....*....|....*....|....*....|.
gi 25146553 424 KCRQYVKFIEDFIKVPIVYIGVGAERESLIV 454
Cdd:PRK13787 391 KCKNYISALEKWIGVKINLVSTGPDRKDTII 421
|
|
| PRK13786 |
PRK13786 |
adenylosuccinate synthetase; Provisional |
32-450 |
4.60e-120 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184325 Cd Length: 424 Bit Score: 357.19 E-value: 4.60e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 32 SVLLGAQWGDEGKGKIIDYLIENHkiNVTARCQGGNNAGHTVVANGRKYDFHILPSGIIsptcFN---VIGNGVVVNLDA 108
Cdd:PRK13786 3 TIITGAQFGDEGKGKIVDLLAKDY--DIVARFQGGDNAGHTVKVGDEVYKLHLIPSGFL----LDarvLIGPGVVLNPEV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 109 FFSELAhngILEESGWE---KRIMISSEAHLVFGVHSQVDGRQEDSLaaKNKIGTTNRGIGPTYSSKCFRNGIRVADLMa 185
Cdd:PRK13786 77 LAEEID---MLEKHGVKvdaEKLGIDAKTSIIMPYHIELDGLRESAR--TEKIGTTKRGIGFAYIDKIARDEVRMSDLV- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 186 DFEEFSEKYRRLVEHYKKQF------PSIeVNVDEELAKFKQHREKLAelKLVGDTVGFIHEQRNAGKQVLVEGANGALL 259
Cdd:PRK13786 151 DKERLMRRLEELAPQKEKEIkelggdPSI-VRDEALIDKYLELGRQLA--PYITDVSYEINKALDEGKSVLAEGAQGTHL 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 260 DIDFGTYPYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCG 339
Cdd:PRK13786 228 DVIHGTQKFVTSSSTIAGSACANLGVGPTRVDNVLGIVKAYITRVGEGPLPTELKDEAGEHLQDVGGEFGTTTGRPRRCG 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 340 WIDLFLLRRSAMINGYTAIALTKLDILDTFPTIKVAVGYKLNGQVLSSPPAQANAWGAIEVEYKEFEGWNEPTVGVRKFE 419
Cdd:PRK13786 308 WFDLPLLKKAIYLNGYTEIALTKLDVLTGLDPIKICVGYELDGEILDYPPELTSDLARCVPVYEELEGWSTDLTEVKAYE 387
|
410 420 430
....*....|....*....|....*....|.
gi 25146553 420 DLPEKCRQYVKFIEDFIKVPIVYIGVGAERE 450
Cdd:PRK13786 388 DLPENARNYVERLEELMGVPIKYISVGPGRE 418
|
|
| PRK13788 |
PRK13788 |
adenylosuccinate synthetase; Provisional |
34-450 |
6.27e-119 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184326 [Multi-domain] Cd Length: 404 Bit Score: 353.34 E-value: 6.27e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 34 LLGAQWGDEGKGKIIDYLIENHKINVtaRCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFFSEL 113
Cdd:PRK13788 6 IIGAQWGDEGKGKVVDALAPEADFVV--RYQGGANAGHTVVAKGKTFKLNLLPSGVLHPHATSVLGDGMVIDPFRFAEER 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 114 AHngiLEESGWEKRIMISSEAHLVFGVHSQVDGRqedslaaKNKIGTTNRGIGPTYSSKCFRNGIRVADLMaDFEEFSEK 193
Cdd:PRK13788 84 EN---LRAGGLNPKLLISERAHLVLPHHKYVDGR-------KNFVGTTGRGIGPAYSDRARRVGIRFGDLL-DEAVLRER 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 194 YRRLVEhyKKQFPSIEV---NVDEELAKFKQHREKLAelKLVGDTVGFIHEQRNAGKQVLVEGANGALLDIDFGTYPYVT 270
Cdd:PRK13788 153 VERLLE--AKPNSTREAgwdTVEKALADLAPMREILL--PFIADTGSLLREAIREGKRVLFEGAQATLLDLNYGTYPYVT 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 271 SSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIG----KEVGVTTGRKRRCGWIDLFLL 346
Cdd:PRK13788 229 SSHPTVGGILVGAGVNHKAINKVYGVAKAFTTRVGHGPFPTEVFGEMAIRLRGKGgnpwDEFGTTTGRARRVGWLDLVLL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 347 RRSAMINGYTAIALTKLDILDTFPTIKVAVGYKLNGQVLssppaqanawgaieveYKEFEGWNEpTVGVRKFEDLPEKCR 426
Cdd:PRK13788 309 KYACEVNGFDGLVLTKLDVLSGLEKVKVCVEYDDDGQPV----------------YKELPGWGD-LDGVKSREALPKEAQ 371
|
410 420
....*....|....*....|....
gi 25146553 427 QYVKFIEDFIKVPIVYIGVGAERE 450
Cdd:PRK13788 372 AYLELIEETTGVPVVMFSTSPRRE 395
|
|
| PRK13783 |
PRK13783 |
adenylosuccinate synthetase; Provisional |
32-453 |
3.54e-117 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237505 Cd Length: 404 Bit Score: 349.02 E-value: 3.54e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 32 SVLLGAQWGDEGKGKIIDYLIENHKINVtaRCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFFS 111
Cdd:PRK13783 3 RVIVGLQWGDEGKGKVVTYLSRYYDIVV--RYSGGANAGHTVNYGDFKVVHHLLPSADFKKNVGAAIGNGVVLDLEVLVE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 112 ELAhngILEES--GWEKRIMISSEAHLVFGVHSQVDGRQEDSLaaKNKIGTTNRGIGPTYSSKCFRNGIRVADLMaDFEE 189
Cdd:PRK13783 81 ELE---ELKEKfpDYSGRIFISELAHVVLPVHKELDEIIESVR--KNAIGTTKRGIGPAYADKVMRVGVRLADLF-DEEK 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 190 FSEKYRRLVEHYKKQFpSIEVNVDEELAKFKQHREKLaeLKLVGDTVGFIHEQRNagKQVLVEGANGALLDIDFGTYPYV 269
Cdd:PRK13783 155 LREFLEKILSLYKKLY-GIEFDVEKMMEDLLTFYEKI--KDLVVSPVEIKRILEE--KSVLFEGTQGVLLDLDVGTYPYV 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 270 TSSNSTVGGACTGIGVPpTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWIDLFLLRRS 349
Cdd:PRK13783 230 TSSNCSTTGVSAGMGFP-VKVDEVIGVFKAYTTRVGEGPFPTELFGEEGEKLRKAGHEYGATTGRPRRCGWLDLPLLRYA 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 350 AMINGYTAIALTKLDILDTFPTIKVAVGYKLNGQVLSSpPAQANAWGAIEVEYKEFEGWNepTVGVRKFEDlpekcrqYV 429
Cdd:PRK13783 309 IEVSGVDSLVMTKADVLNGFEKIKVCVRYEIGGKEVRD-PSSLRDLEKAEPVYEEFDGWK--SLEDKNFLK-------FV 378
|
410 420
....*....|....*....|....
gi 25146553 430 KFIEDFIKVPIVYIGVGAERESLI 453
Cdd:PRK13783 379 DFIERETGRKIAYISTGPKIEEIV 402
|
|
| PRK13785 |
PRK13785 |
adenylosuccinate synthetase; Provisional |
30-457 |
8.53e-115 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237506 Cd Length: 454 Bit Score: 344.82 E-value: 8.53e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 30 TVSVLlGAQWGDEGKGKIIDylIENHKINVTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTcFNVIGNGVVVNLDAF 109
Cdd:PRK13785 2 TVTIV-GSQLGDEGKGGVVD--LYGDAADVVVRYQGGDNAGHTVVHGGEEYKLSLVPSGAVRGK-IGVLGNGCVVNPETL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 110 FSELahnGILEESGWEKRIMISSEAHLVFGVHSQVDGRQEDSLAAKN-KIGTTNRGIGPTYSSKCFRNGIRVADLM---- 184
Cdd:PRK13785 78 FDEI---DALRERGLDPDVRVAERAHVILPYHRVLDGIEEEAKSDSDlEVGTTGRGIGPTYEDKAGRRGVRVGDLLdpdv 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 185 --ADFEEFSEKYRRLVEH-YKKQFPSI--EVNVDEELAKFKQHREKLAELKLVGDTVGFIHEQRNAGKQVLVEGANGALL 259
Cdd:PRK13785 155 lrDRLEYVVPQKRALAEDvYGLDASETpeAFDVDALFEEYREYGERLAEEDMTVNAGDFLAERIDDGDNVMLEGAQGTSI 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 260 DIDFGTYPYVTSSNSTVGGACTGIGVPPTAVGN--VIGVVKAYQTRVGTGPFPTEL-----------FDSDGEKLQTI-- 324
Cdd:PRK13785 235 DIDHGNYPYVTSSNPTAGGAATGTGLGPTVVGQgeVVGIVKAYLSRVGSGPLPTELggvegdtpdegGRPDEEELATYir 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 325 --GKEVGVTTGRKRRCGWIDLFLLRRSAMINGYTAIALTKLDILDTFPTIKVAVGYKLNGQVLSSPPAQANAWGAIEVEY 402
Cdd:PRK13785 315 eeGGEYGTVTGRPRRVGWLDMPMLRHAARASGFTGLAINHIDVLAGLDEVKVGHSYELDGEELLTMPATTERWARCEPNF 394
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 25146553 403 KEFEGWNE---PTVGVRKFEDLPEKCRQYVKFIEDFIKVPIVYIGVGAERESLIVRQQ 457
Cdd:PRK13785 395 RSFDGWPEvdwAAVAEEGYDALPENARTYLEYVSDELDTPIYAVGVGPGREETVVLEN 452
|
|
| PRK13784 |
PRK13784 |
adenylosuccinate synthetase; Provisional |
33-453 |
1.19e-89 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172322 Cd Length: 428 Bit Score: 279.21 E-value: 1.19e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 33 VLLGAQWGDEGKGKIIDYLIEnhKINVTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAFFSE 112
Cdd:PRK13784 5 VIVGAQWGDEGKGKIADTLAE--KADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKCVIGHGVVLDPVALDEE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 113 LAHngiLEESGWE---KRIMISSEAHLVFGVHSQVDGRQEDSlaAKNKIGTTNRGIGPTYSSKCFRNGIRVADLMAD--- 186
Cdd:PRK13784 83 ITR---LQAKGIAisaENLFVSESCTIITSYHKLLDAVRESN--TSEKIGTTGKGIGPAYEDKVSRKGIKFKHLFDKdll 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 187 ----FEEFSEKYRRLVEHYKKQFPSIEvnvdEELAKFKQHREKLAELKlvGDTVGFIHEQRNAGKQVLVEGANGALLDID 262
Cdd:PRK13784 158 rsrlAISLAEKETLFRDLYKVEYPTLE----QEFDKLFALGQKLKQYA--ADTFSIIDQAIAAGKNVVYEGAQGVLLDVD 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 263 FGTYPYVTSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIGKEVGVTTGRKRRCGWID 342
Cdd:PRK13784 232 YGTYPFVTSSNTSVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWLD 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 343 LFLLRRSAMINGYTAIALTKLDILDTFPTIKVAVGYKLNGQVLSSPPAQANAWgAIEVEYKEFEGWNEPTVGVRkfEDLP 422
Cdd:PRK13784 312 LPLLKYSAKCSNLTSIALTKVDVLSDMDTLKVCIGYKYEGKEIYCAYPGIDLY-KVEPILVEMEPFSIDETVTK--DNMP 388
|
410 420 430
....*....|....*....|....*....|.
gi 25146553 423 EKCRQYVKFIEDFIKVPIVYIGVGAERESLI 453
Cdd:PRK13784 389 AALKTYLKTIENHVGIPISSLAYGPSREQIL 419
|
|
| PRK04293 |
PRK04293 |
adenylosuccinate synthetase; Provisional |
30-453 |
1.30e-84 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 179812 Cd Length: 333 Bit Score: 262.89 E-value: 1.30e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 30 TVSVLLGAQWGDEGKGKIIDYLIENHKINVTARCQGGNNAGHTVVANGRKYDFHILPSGIISPTCFNVIGNGVVVNLDAF 109
Cdd:PRK04293 2 TCTIVVGGFFGDEGKGKIIAYLALKDKPSIIARGGVGPNAGHTVEYNGKKYGLRMIPSGFVNKDAKLAIGAGVLVDPEVL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 110 FSELAHNGILEESGWEKRIMISSEAHlvfgvhsqVDGRQEDSLAAKnKIGTTNRGIGPTYSSKCFRngirVADLMADFEE 189
Cdd:PRK04293 82 LKEVEELNVGGRVFVDYRCGIIEEKH--------VEEDRSDEHLSK-KIGSTGTGCGPANADRVLR----RLKLAKDVEE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 190 fsekyrrlvehykkqfpsievnvdeeLAKFkqhreklaelklVGDTVGFIHEQRNAGKQVLVEGANGALLDIDFGTYPYV 269
Cdd:PRK04293 149 --------------------------LEKY------------LTDVPEEVNEALDRGENVLIEGTQGFGLSLYYGTYPYV 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 270 TSSNSTVGGACTGIGVPPTAVGNVIGVVKAYQTRVGTGPFPTELFDSDGEKLQTIgkEVGVTTGRKRRCGWIDLFLLRRS 349
Cdd:PRK04293 191 TSKDTTASGIASDVGVGPTKVDEVIVVFKSYPTRVGEGPFPTELSLEEAEKLGLV--EYGTVTGRRRRVGPFDFELARRA 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 350 AMINGYTAIALTKLDILDtfptikvavgyklngqvlssPPAQanawgaieveykefegwneptvGVRKFEDLPEKCRQYV 429
Cdd:PRK04293 269 ARINGATQIAITKLDKLD--------------------KEAY----------------------GVTEYDKLPPEAKKFI 306
|
410 420
....*....|....*....|....
gi 25146553 430 KFIEDFIKVPIVYIGVGAERESLI 453
Cdd:PRK04293 307 EEIEEELGVPVTLISTGPELEDTI 330
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
31-354 |
1.37e-27 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 111.31 E-value: 1.37e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 31 VSVLLGAQWGDEGKGKIIDYLIE--NHKINVTArcqGGNNAGHTVV-ANGRKYDFHILPSGIISPTCFNV-IGNGVVVNL 106
Cdd:NF038379 1 VDVVVDGQFGSTGKGLIAGYLAEraAPDVVVRA---AGPNAGHTYIdDEGRKFVHRMLPNGIVSPPLKQVlIGPGSEIDL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 107 DAFFSE-LAHNGILEESGweKRIMISSEAHLVFGvHSQVDgrQEDSLAAknKIGTTNRGIGPTYSSKCFRNGIRVADLMA 185
Cdd:NF038379 78 EVLREEiEELEDAGHDVG--KRLLIHEQATVIEL-HKHVE--EEAGPMT--KIGSTKKGIGAARAAKIRRNPSTLGDAEG 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 186 DFEEFSEKYRRLVEHykkqfpsiEVNVDEELAKFKQHReklaelklvgdtvgfiheqrnaGKQVLVEGANGALLDIDFGT 265
Cdd:NF038379 151 DFGEGAVRDQPWEIA--------ERVVDNALYDFALQA----------------------AERIQIEGTQGYSLGLHAGF 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 266 YPYVTSSNSTVGGACTGIGVPPTAV--GNVIGVVKAYQTRVGT-----GPFPTEL-FDSDG--EKLQTIGKEVgvttgrk 335
Cdd:NF038379 201 YPYCTSRDCTPADFLADAGIPLPNVdaFKVVGTARTYPIRVAGwsgnsYPDQGETtWEELGlpEELTTVTKKV------- 273
|
330
....*....|....*....
gi 25146553 336 RRCGWIDLFLLRRSAMING 354
Cdd:NF038379 274 RRVGTFSAEQVREAVQANG 292
|
|
| PTZ00351 |
PTZ00351 |
adenylosuccinate synthetase; Provisional |
31-324 |
2.86e-14 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 173544 Cd Length: 710 Bit Score: 75.09 E-value: 2.86e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 31 VSVLLGAQWGDEGKGKIIDYLIENHKINVTARCQGGNNAGHTVVAN-GRKYDFHILPSGIISPTCFNVIGNGVVVNLDAF 109
Cdd:PTZ00351 171 VIMVAGAFFGDEGKGKTVDAVAHHPLCTCIARVNSGENAGHTVYDKaGRKFVFNLAPSGLLLPGKRNYIGPECVMDPVSF 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 110 FSELAHNGILEESGWEKRIMISSEAhLVFGVHSQVDgrqedsLAAKNKIGTTNRGIGPTYSSKCFRNGIRVADLMADFEE 189
Cdd:PTZ00351 251 MEKEIIQLIDAGIDYRDRLFIGNVC-IVTPYHKLLD------LLGSAANSSTLKGMAPVHGSKVMKRGIRLDHIFNDDET 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 190 FSEKYRRLVEHY------------------KKQFPSIEVNVDEELAKFKQHREKLAEL-KLVGDTV----------GFIH 240
Cdd:PTZ00351 324 LRKRLEKDMDTYlgllkvknlsdadvvrlcREENSDGVVRVPDYVIAFAQAKDKVEFLvKLYRDRVrhnpdfparcDVTY 403
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25146553 241 EQRNA---GKQVLVEGANGALL-DIDFGTYPYVTSSNSTVGGACTGIGVPPTAVGNVI-GVVKAY-QTRVGTGPFPTELF 314
Cdd:PTZ00351 404 ELHAAvlrGEKVLLEGPQSYWLsNARTKFWESTTSADTTAAGLLAASQLNFQKFKSVVlNVHKAPgSSRVGIGACPSSFV 483
|
330
....*....|
gi 25146553 315 DSDGEKLQTI 324
Cdd:PTZ00351 484 PQDYFSAQNI 493
|
|
| |
