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Conserved domains on  [gi|25144157|ref|NP_741143|]
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3-hydroxyisobutyryl-CoA hydrolase, mitochondrial [Caenorhabditis elegans]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 11240944)

enoyl-CoA hydratase/isomerase family protein plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate; similar to Homo sapiens 3-hydroxyisobutyryl-CoA hydrolase and Cereibacter sphaeroides Enoyl-CoA hydratase

CATH:  3.90.226.10
EC:  3.1.2.-
Gene Ontology:  GO:0016790
PubMed:  18470480|11263873
SCOP:  4004188

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
46-375 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


:

Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 528.19  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157    46 VVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDVLAVVRSFKDsESGKECtmhKDFFREEY 125
Cdd:pfam16113   3 VITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKA-GGGEAG---RDFFREEY 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   126 ILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKGNLGMYLALTGYRL 205
Cdd:pfam16113  79 RLNYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARL 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   206 LGADAFHAGLATHFVESSELAKLEKELVNIKDVTENSVDEVIRSF-EPKKIPEFSLSKNLAQIRDSFKAKSVEEILASLE 284
Cdd:pfam16113 159 NGADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFaEESDPPPSPLAAHREAIDRCFSADTVEEIIAALE 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   285 K--DGSDWAKKQAATLGKMSPTSLKVTHRQITEGSKMSYAKIFTMEYRLTQRFLADKDFHEGCRAILVDKDRKPKWNPAT 362
Cdd:pfam16113 239 AeaDGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPKWSPAT 318
                         330
                  ....*....|...
gi 25144157   363 LADVKDSVVDNYF 375
Cdd:pfam16113 319 LEEVTDEMVDAYF 331
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
46-375 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 528.19  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157    46 VVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDVLAVVRSFKDsESGKECtmhKDFFREEY 125
Cdd:pfam16113   3 VITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKA-GGGEAG---RDFFREEY 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   126 ILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKGNLGMYLALTGYRL 205
Cdd:pfam16113  79 RLNYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARL 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   206 LGADAFHAGLATHFVESSELAKLEKELVNIKDVTENSVDEVIRSF-EPKKIPEFSLSKNLAQIRDSFKAKSVEEILASLE 284
Cdd:pfam16113 159 NGADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFaEESDPPPSPLAAHREAIDRCFSADTVEEIIAALE 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   285 K--DGSDWAKKQAATLGKMSPTSLKVTHRQITEGSKMSYAKIFTMEYRLTQRFLADKDFHEGCRAILVDKDRKPKWNPAT 362
Cdd:pfam16113 239 AeaDGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPKWSPAT 318
                         330
                  ....*....|...
gi 25144157   363 LADVKDSVVDNYF 375
Cdd:pfam16113 319 LEEVTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
35-377 4.66e-152

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 432.71  E-value: 4.66e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   35 EILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDVLAVvrsFKDSESGKEC 114
Cdd:PRK05617   4 EVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRAL---YEAARAGDPL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  115 TmHKDFFREEYILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKGNL 194
Cdd:PRK05617  81 A-ADRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGAL 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  195 GMYLALTGYRLLGADAFHAGLATHFVESSELAKLEKELVNIK-DVTENSVDEVIRSFEPKKiPEFSLSKNLAQIRDSFKA 273
Cdd:PRK05617 160 GTYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRwDSGADVVDAALAAFATPA-PASELAAQRAWIDECFAG 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  274 KSVEEILASLEKDGSDWAKKQAATLGKMSPTSLKVTHRQITEGSKMSYAKIFTMEYRLTQRFLADKDFHEGCRAILVDKD 353
Cdd:PRK05617 239 DTVEDIIAALEADGGEFAAKTADTLRSRSPTSLKVTLEQLRRARGLTLEECLRRELRLALAMLRSPDFVEGVRAVLIDKD 318
                        330       340
                 ....*....|....*....|....
gi 25144157  354 RKPKWNPATLADVKDSVVDNYFSP 377
Cdd:PRK05617 319 RNPKWSPATLEDVTPEDVEAFFAP 342
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
36-233 6.27e-56

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 181.99  E-value: 6.27e-56
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  36 ILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVLAVVRSFKDSESGKEct 115
Cdd:cd06558   1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAALSDAGEEARA-- 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157 116 mhkdFFREEYILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKG-NL 194
Cdd:cd06558  78 ----FIRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGpAR 153
                       170       180       190
                ....*....|....*....|....*....|....*....
gi 25144157 195 GMYLALTGYRLLGADAFHAGLATHFVESSELAKLEKELV 233
Cdd:cd06558 154 ARELLLTGRRISAEEALELGLVDEVVPDEELLAAALELA 192
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
36-349 1.72e-44

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 154.17  E-value: 1.72e-44
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  36 ILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDvLAVVRSFKDSESGKect 115
Cdd:COG1024   1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGAD-LKELAAAADPEEAR--- 75
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157 116 mhkDFFREEYILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKG-NL 194
Cdd:COG1024  76 ---AFARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGlAR 152
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157 195 GMYLALTGYRLLGADAFHAGLATHFVESSELaklekelvnikdvtensvdevirsfepkkipefslsknLAQirdsfkak 274
Cdd:COG1024 153 AKELLLTGRRIDAEEALELGLVNRVVPDDEL--------------------------------------LAA-------- 186
                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 25144157 275 sveeilaslekdgsdwAKKQAATLGKMSPTSLKVTHRQITEGSKMSYAKIFTMEYRLTQRFLADKDFHEGCRAIL 349
Cdd:COG1024 187 ----------------ALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFL 245
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
47-242 8.05e-16

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 76.43  E-value: 8.05e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157    47 VTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDVLAVVRSFKDSESGKECTMHKDFFReeyi 126
Cdd:TIGR01929  16 ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDKAFCSGGDQKVRGDYGYIDDSGVHRLNVLDVQR---- 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   127 lnhLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKGN-LGMYLALTGYRL 205
Cdd:TIGR01929  92 ---QIRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMARIVGQkKAREIWFLCRQY 168
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 25144157   206 LGADAFHAGLATHFVessELAKLEKELVNI-KDVTENS 242
Cdd:TIGR01929 169 DAKQALDMGLVNTVV---PLADLEKETVRWcREILQKS 203
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
46-375 0e+00

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 528.19  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157    46 VVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDVLAVVRSFKDsESGKECtmhKDFFREEY 125
Cdd:pfam16113   3 VITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKA-GGGEAG---RDFFREEY 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   126 ILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKGNLGMYLALTGYRL 205
Cdd:pfam16113  79 RLNYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGELGLYLALTGARL 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   206 LGADAFHAGLATHFVESSELAKLEKELVNIKDVTENSVDEVIRSF-EPKKIPEFSLSKNLAQIRDSFKAKSVEEILASLE 284
Cdd:pfam16113 159 NGADALAAGLATHYVPSARLPALEEALAALDWSDPADVDAVLAEFaEESDPPPSPLAAHREAIDRCFSADTVEEIIAALE 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   285 K--DGSDWAKKQAATLGKMSPTSLKVTHRQITEGSKMSYAKIFTMEYRLTQRFLADKDFHEGCRAILVDKDRKPKWNPAT 362
Cdd:pfam16113 239 AeaDGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKLSLAECLRMEYRLALRCLRRPDFVEGVRALLIDKDRNPKWSPAT 318
                         330
                  ....*....|...
gi 25144157   363 LADVKDSVVDNYF 375
Cdd:pfam16113 319 LEEVTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
35-377 4.66e-152

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 432.71  E-value: 4.66e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   35 EILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDVLAVvrsFKDSESGKEC 114
Cdd:PRK05617   4 EVLAEVEGGVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRAL---YEAARAGDPL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  115 TmHKDFFREEYILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKGNL 194
Cdd:PRK05617  81 A-ADRFFREEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGAL 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  195 GMYLALTGYRLLGADAFHAGLATHFVESSELAKLEKELVNIK-DVTENSVDEVIRSFEPKKiPEFSLSKNLAQIRDSFKA 273
Cdd:PRK05617 160 GTYLALTGARISAADALYAGLADHFVPSADLPALLDALISLRwDSGADVVDAALAAFATPA-PASELAAQRAWIDECFAG 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  274 KSVEEILASLEKDGSDWAKKQAATLGKMSPTSLKVTHRQITEGSKMSYAKIFTMEYRLTQRFLADKDFHEGCRAILVDKD 353
Cdd:PRK05617 239 DTVEDIIAALEADGGEFAAKTADTLRSRSPTSLKVTLEQLRRARGLTLEECLRRELRLALAMLRSPDFVEGVRAVLIDKD 318
                        330       340
                 ....*....|....*....|....
gi 25144157  354 RKPKWNPATLADVKDSVVDNYFSP 377
Cdd:PRK05617 319 RNPKWSPATLEDVTPEDVEAFFAP 342
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
24-386 1.61e-107

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 320.98  E-value: 1.61e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   24 MSFSVSAAAKSEILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVlavvR 103
Cdd:PLN02874   1 MAQQVQNPAEEVVLGEEKGRVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAG-RAFSAGGDL----K 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  104 SFKDSESGKECTmhKDFFREEYILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGG 183
Cdd:PLN02874  76 MFYDGRESDDSC--LEVVYRMYWLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGF 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  184 SYFLSRLKGNLGMYLALTGYRLLGADAFHAGLATHFVESSELAKLEKELVNIKDVTENSVDEVIRSF-EPKKIPEFSLSK 262
Cdd:PLN02874 154 SYILSRLPGHLGEYLALTGARLNGKEMVACGLATHFVPSEKLPELEKRLLNLNSGDESAVQEAIEEFsKDVQADEDSILN 233
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  263 NLAQIRDSFKAKSVEEILASLE----KDGSDWAKKQAATLGKMSPTSLKVTHRQITEGSKMSYAKIFTMEYRLTQ---RF 335
Cdd:PLN02874 234 KQSWINECFSKDTVEEIIKAFEseasKTGNEWIKETLKGLRRSSPTGLKITLRSIREGRKQSLAECLKKEFRLTMnilRS 313
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|.
gi 25144157  336 LADKDFHEGCRAILVDKDRKPKWNPATLADVKDSVVDNYFSPLPNNSDLKL 386
Cdd:PLN02874 314 TVSDDVYEGIRALVIDKDNAPKWNPSTLDEVTDEKVDLVFQPFKAREELQL 364
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
27-386 6.07e-101

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 304.33  E-value: 6.07e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   27 SVSAAAKSEILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVLAVVRsfk 106
Cdd:PLN02988   2 AVEMASQSQVLVEEKSSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAAVVR--- 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  107 DSESGKeCTMHKDFFREEYILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYF 186
Cdd:PLN02988  78 DIEQGN-WRLGANFFSDEYMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYF 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  187 LSRLKGNLGMYLALTGYRLLGADAFHAGLATHFVESSELAKLEKELVNIKDVTENSVDEVIRSF--EPKKIPEfSLSKNL 264
Cdd:PLN02988 157 LSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSTRLTALEADLCRIGSNDPTFASTILDAYtqHPRLKPQ-SAYHRL 235
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  265 AQIRDSFKAKSVEEILASLEKDGSD----WAKKQAATLGKMSPTSLKVTHRQITEGSKMSYAKIFTMEYRLTQRFLA--- 337
Cdd:PLN02988 236 DVIDRCFSRRTVEEIISALEREATQeadgWISATIQALKKASPASLKISLRSIREGRLQGVGQCLIREYRMVCHVMKgei 315
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|..
gi 25144157  338 DKDFHEGCRAILVDKDRKPKWNPATLADVKDSVVDNYFSPLPNN---SDLKL 386
Cdd:PLN02988 316 SKDFVEGCRAILVDKDKNPKWEPRRLEDMKDSMVEQYFERVEEEeewDDLKL 367
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
16-386 3.36e-85

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 264.53  E-value: 3.36e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   16 HSKEVCQKMSFSVSAAAKSEILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAG 95
Cdd:PLN02851  24 YGRSFSALPNYAANDDLQDQVLVEGRAKSRAAILNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSG-RAFCSG 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   96 GDVLAVVRSFKDSESgKECtmhKDFFREEYILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETAL 175
Cdd:PLN02851 103 ADVVSLYHLINEGNV-EEC---KLFFENLYKFVYLQGTYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQM 178
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  176 GLFPDVGGSYFLSRLKGNLGMYLALTGYRLLGADAFHAGLATHFVESSELAKLE----KELVNIKDVTENSVDEVIRSFE 251
Cdd:PLN02851 179 GFHPDAGASYYLSRLPGYLGEYLALTGQKLNGVEMIACGLATHYCLNARLPLIEerlgKLLTDDPAVIEDSLAQYGDLVY 258
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  252 PKKIpefSLSKNLAQIRDSFKAKSVEEILASLEKDGS----DWAKKQAATLGKMSPTSLKVTHRQITEGSKMSYAKIFTM 327
Cdd:PLN02851 259 PDKS---SVLHKIETIDKCFGHDTVEEIIEALENEAAssydEWCKKALKKIKEASPLSLKVTLQSIREGRFQTLDQCLAR 335
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 25144157  328 EYRLT----QRFLADkDFHEGCRAILVDKDRKPKWNPATLADVKDSVVDNYFSPLPN-NSDLKL 386
Cdd:PLN02851 336 EYRISlcgvSKWVSG-DFCEGVRARLVDKDFAPKWDPPSLGEVSKDMVDCYFTPLDEsESELEL 398
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
35-386 1.59e-72

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 231.88  E-value: 1.59e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   35 EILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVLAV--VRSFKDSESGK 112
Cdd:PLN02157  38 QVLVEGSGCSRTAILNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSG-RAFCAGGDIVSLyhLRKRGSPDAIR 116
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  113 EctmhkdFFREEYILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKG 192
Cdd:PLN02157 117 E------FFSSLYSFIYLLGTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLPG 190
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  193 NLGMYLALTGYRLLGADAFHAGLATHFVESSELAKLEKELVNI----KDVTENSVDEVIRSFEPKKIpefSLSKNLAQIR 268
Cdd:PLN02157 191 RLGEYLGLTGLKLSGAEMLACGLATHYIRSEEIPVMEEQLKKLltddPSVVESCLEKCAEVAHPEKT---GVIRRIDLLE 267
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  269 DSFKAKSVEEILASLEKDGS----DWAKKQAATLGKMSPTSLKVTHRQITEGSKMSYAKIFTMEYRLTQRFL---ADKDF 341
Cdd:PLN02157 268 KCFSHDTVEEIIDSLEIEAGrrkdTWCITTLRRLKESSPLSLKVALRSIREGRLQTLDQCLIREYRMSLQGLigpMSGNF 347
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*.
gi 25144157  342 HEGCRAILVDKDRKPKWNPATLADVKDSVVDNYFSPL-PNNSDLKL 386
Cdd:PLN02157 348 CEGVRARLIDKDEAPKWDPPSLEKVSEDMVDDYFCALtPTEPDLDL 393
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
36-233 6.27e-56

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 181.99  E-value: 6.27e-56
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  36 ILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVLAVVRSFKDSESGKEct 115
Cdd:cd06558   1 VLVERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAALSDAGEEARA-- 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157 116 mhkdFFREEYILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKG-NL 194
Cdd:cd06558  78 ----FIRELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGpAR 153
                       170       180       190
                ....*....|....*....|....*....|....*....
gi 25144157 195 GMYLALTGYRLLGADAFHAGLATHFVESSELAKLEKELV 233
Cdd:cd06558 154 ARELLLTGRRISAEEALELGLVDEVVPDEELLAAALELA 192
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
36-349 1.72e-44

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 154.17  E-value: 1.72e-44
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  36 ILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDvLAVVRSFKDSESGKect 115
Cdd:COG1024   1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGAD-LKELAAAADPEEAR--- 75
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157 116 mhkDFFREEYILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKG-NL 194
Cdd:COG1024  76 ---AFARGLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGlAR 152
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157 195 GMYLALTGYRLLGADAFHAGLATHFVESSELaklekelvnikdvtensvdevirsfepkkipefslsknLAQirdsfkak 274
Cdd:COG1024 153 AKELLLTGRRIDAEEALELGLVNRVVPDDEL--------------------------------------LAA-------- 186
                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 25144157 275 sveeilaslekdgsdwAKKQAATLGKMSPTSLKVTHRQITEGSKMSYAKIFTMEYRLTQRFLADKDFHEGCRAIL 349
Cdd:COG1024 187 ----------------ALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDAREGIAAFL 245
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
30-356 9.41e-29

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 112.65  E-value: 9.41e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   30 AAAKSEILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVlavvRSFkDSE 109
Cdd:PRK06688   1 MTMVTDLLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAG-RAFSAGGDI----KDF-PKA 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  110 SGKECTMHKDFFReeyiLNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSR 189
Cdd:PRK06688  75 PPKPPDELAPVNR----FLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPR 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  190 LKGN-LGMYLALTGYRLLGADAFHAGLATHFVESSELaklekelvnikdvtensvdevirsfepkkipefslsknlaqir 268
Cdd:PRK06688 151 LIGRaRAAEMLLLGEPLSAEEALRIGLVNRVVPAAEL------------------------------------------- 187
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  269 DSFkaksveeilaslekdgsdwAKKQAATLGKMSPTSLKVTHRQITEGSKMSYAKIFTMEYRLTQRFLADKDFHEGCRAI 348
Cdd:PRK06688 188 DAE-------------------ADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLLRTPDFREGATAF 248

                 ....*...
gi 25144157  349 LvDKdRKP 356
Cdd:PRK06688 249 I-EK-RKP 254
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
46-232 1.39e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 112.14  E-value: 1.39e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   46 VVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDVlavvrsfkdsesgKE-CTMHKDFFREE 124
Cdd:PRK07657  16 KITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADL-------------KErAGMNEEQVRHA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  125 YIL----NHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKG-NLGMYLA 199
Cdd:PRK07657  83 VSLirttMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGvGRAKELI 162
                        170       180       190
                 ....*....|....*....|....*....|...
gi 25144157  200 LTGYRLLGADAFHAGLATHFVESSELAKLEKEL 232
Cdd:PRK07657 163 YTGRRISAQEAKEIGLVEFVVPAHLLEEKAIEI 195
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
36-234 6.82e-27

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 107.53  E-value: 6.82e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   36 ILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDVlAVVRSFKDSESGKECT 115
Cdd:PRK05809   6 VILEKEGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADI-SEMKDLNEEEGRKFGL 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  116 MHKDFFREeyilnhlIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKGnLG 195
Cdd:PRK05809  85 LGNKVFRK-------LENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVG-PG 156
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 25144157  196 MY--LALTGYRLLGADAFHAGLATHFVESSELAKLEKELVN 234
Cdd:PRK05809 157 KAkeLIYTGDMINAEEALRIGLVNKVVEPEKLMEEAKALAN 197
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
35-215 3.37e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 102.55  E-value: 3.37e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   35 EILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVLAVVRSFKDsesgkec 114
Cdd:PRK06072   1 MIKVESREGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEG-RAFCVGADLSEFAPDFAI------- 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  115 tmhkDFFREEYILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKGNL 194
Cdd:PRK06072  73 ----DLRETFYPIIREIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQR 148
                        170       180
                 ....*....|....*....|.
gi 25144157  195 GMYLALTGYRLLGADAFHAGL 215
Cdd:PRK06072 149 FYEILVLGGEFTAEEAERWGL 169
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
36-225 6.43e-25

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 102.14  E-value: 6.43e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   36 ILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDvlavVRSFKDSESGKECT 115
Cdd:PRK05980   5 VLIEIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGAD----IHEFSASVAAGADV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  116 MHKDFFREEYILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKG-NL 194
Cdd:PRK05980  81 ALRDFVRRGQAMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGrKR 160
                        170       180       190
                 ....*....|....*....|....*....|.
gi 25144157  195 GMYLALTGYRLLGADAFHAGLATHFVESSEL 225
Cdd:PRK05980 161 ALELLLTGDAFSAERALEIGLVNAVVPHEEL 191
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
46-293 7.47e-25

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 101.67  E-value: 7.47e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157    46 VVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGsGDKAFCAGGDVLavvrsfkdsESGKECTMHKDFFREEY 125
Cdd:pfam00378   8 VITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTG-GDKAFCAGADLK---------EMYGEGPAHQALYRENV 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   126 I-LNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKG-NLGMYLALTGY 203
Cdd:pfam00378  78 LdLWTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGhSKAMEMLLLGR 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   204 RLLGADAFHAGLATHFV-----ESSELAKLEKELVNIKDVTENSVDEVIRSFEPKKIPEFSLSKNLAQirDSF-KAKSVE 277
Cdd:pfam00378 158 RISAQEALKWGLVDKVVpedqlLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFY--STFsKDDIIE 235
                         250
                  ....*....|....*.
gi 25144157   278 EILASLEKDGSDWAKK 293
Cdd:pfam00378 236 GLQAFLEKRKPPWEDQ 251
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
36-261 1.13e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 98.58  E-value: 1.13e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   36 ILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSgDKAFCAGGDVLAVVR-SFKDSesgkec 114
Cdd:PRK05862   6 ILVETRGRVGLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITGS-EKAFAAGADIKEMADlSFMDV------ 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  115 tmhkdfFREEYILN-HLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKGN 193
Cdd:PRK05862  79 ------YKGDYITNwEKVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGK 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 25144157  194 L-GMYLALTGYRLLGADAFHAGLATHFVESSELaklekelvnikdvtensVDEVIRSFEpkKIPEFSLS 261
Cdd:PRK05862 153 AkAMDLCLTGRMMDAAEAERAGLVSRVVPADKL-----------------LDEALAAAT--TIASFSLP 202
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
36-225 6.94e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 88.11  E-value: 6.94e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   36 ILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSgDKAFCAGGDVlavvrsfkdSESGKECT 115
Cdd:PRK06190   6 LLVETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGA-DPAFCAGLDL---------KELGGDGS 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  116 MHKDFFREEYILNHLiGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLkgnLG 195
Cdd:PRK06190  76 AYGAQDALPNPSPAW-PAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQK---VG 151
                        170       180       190
                 ....*....|....*....|....*....|....
gi 25144157  196 MYLA----LTGYRLLGADAFHAGLATHFVESSEL 225
Cdd:PRK06190 152 IGRArrmsLTGDFLDAADALRAGLVTEVVPHDEL 185
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
36-358 1.28e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 87.40  E-value: 1.28e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   36 ILVDTHGSKKVVTLNRPKALNALNLEMVREFYpklQAWNS-SSDVDL--VILKGSGDKAFCAGGDVlavvrsfKDSESGK 112
Cdd:PRK06494   6 STVERKGHVTIVTLNRPEVMNALHLDAHFELE---EVFDDfAADPEQwvAIVTGAGDKAFSAGNDL-------KEQAAGG 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  113 ECTMHKDFF---REEYilnhligTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSR 189
Cdd:PRK06494  76 KRGWPESGFgglTSRF-------DLDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPR 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  190 ---LKGNLGMYlaLTGYRLLGADAFHAGLathfvesselaklekelvnikdvtensVDEVIrsfepkkipefslsknlaq 266
Cdd:PRK06494 149 qigLKRAMGMI--LTGRRVTAREGLELGF---------------------------VNEVV------------------- 180
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  267 irdsfkakSVEEILASLEKdgsdWAKkqaaTLGKMSPTSLKVTHRQITEGSKMSYAKIFT--MEYRLTQRFLADKDFHEG 344
Cdd:PRK06494 181 --------PAGELLAAAER----WAD----DILACSPLSIRASKQAVYRGLEVSLEEAITaqRDYPAVEARRASQDYIEG 244
                        330
                 ....*....|....
gi 25144157  345 CRAiLVDKdRKPKW 358
Cdd:PRK06494 245 PKA-FAEK-RPPRW 256
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
29-224 2.46e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 86.64  E-value: 2.46e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   29 SAAAKSEILVDTHGSK-KVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGsGDKAFCAGGDVlavvRSFKD 107
Cdd:PRK08138   2 MSTATDVVLLERPADGvALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTG-GEKVFAAGADI----KEFAT 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  108 SESGKECTMHKDFFREEyilnhlIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFL 187
Cdd:PRK08138  77 AGAIEMYLRHTERYWEA------IAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRL 150
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 25144157  188 SRLKGNL-GMYLALTGYRLLGADAFHAGLATHFVESSE 224
Cdd:PRK08138 151 VRAVGKFkAMRMALTGCMVPAPEALAIGLVSEVVEDEQ 188
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
24-225 8.08e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 85.53  E-value: 8.08e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   24 MSFSVSAAAKSEILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDvlavVR 103
Cdd:PRK06127   1 STMSSISSPTGKLLAEKTGGLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGAD----IS 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  104 SFKDSESGKECTMHKDFFREEYILnhLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGG 183
Cdd:PRK06127  77 QFEESRSDAEAVAAYEQAVEAAQA--ALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDG 154
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 25144157  184 SYFLSRLKG-NLGMYLALTGYRLLGADAFHAGLATHFVESSEL 225
Cdd:PRK06127 155 VKNLVDLVGpSAAKDLFYTARRFDAAEALRIGLVHRVTAADDL 197
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
35-290 1.33e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 84.59  E-value: 1.33e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   35 EILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVLAVVRSFK--DSESGK 112
Cdd:PRK05995   5 TLEIEQRGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAG-KAFCAGADLNWMKKMAGysDDENRA 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  113 ECTMHKDFFReeyilnhLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKG 192
Cdd:PRK05995  84 DARRLADMLR-------AIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPYVIRAMGE 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  193 NLGMYLALTGYRLLGADAFHAGLATHFVESSEL----AKLEKELVN------------IKDVTENSVDEVIRSFEPKKIp 256
Cdd:PRK05995 157 RAARRYFLTAERFDAAEALRLGLVHEVVPAEALdakvDELLAALVAnspqavragkrlVRDVAGRPIDAALIADTASRI- 235
                        250       260       270
                 ....*....|....*....|....*....|....
gi 25144157  257 efslsknlAQIRDSFKAKsvEEILASLEKDGSDW 290
Cdd:PRK05995 236 --------ALIRATEEAR--EGVAAFLEKRKPAW 259
PLN02600 PLN02600
enoyl-CoA hydratase
46-224 1.97e-18

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 84.09  E-value: 1.97e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   46 VVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDvLAVVRSFKDSESGKECTMHKDFFReey 125
Cdd:PLN02600   7 ELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGAD-LKERRKMSPSEVQKFVNSLRSTFS--- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  126 ilnhLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKG-NLGMYLALTGYR 204
Cdd:PLN02600  83 ----SLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGrSRAKELIFTGRR 158
                        170       180
                 ....*....|....*....|
gi 25144157  205 LLGADAFHAGLATHFVESSE 224
Cdd:PLN02600 159 IGAREAASMGLVNYCVPAGE 178
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
33-285 2.77e-18

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 83.66  E-value: 2.77e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   33 KSEILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDV--LA---VVRSFKD 107
Cdd:PRK09674   1 MSELLVSRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGNA-RFFAAGADLneMAekdLAATLND 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  108 SesgkectmhkdffREEYIlnHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFL 187
Cdd:PRK09674  80 P-------------RPQLW--QRLQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRL 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  188 SRLKGN-LGMYLALTGYRLLGADAFHAGLATHfVESSELAkLEKELvnikdvtenSVDEVIRSFEP----------KKIP 256
Cdd:PRK09674 145 IRSVGKsLASQMVLTGESITAQQAQQAGLVSE-VFPPELT-LERAL---------QLASKIARHSPlalraakqalRQSQ 213
                        250       260       270
                 ....*....|....*....|....*....|....
gi 25144157  257 EFSLSKNLAQIRDSFKAKSV-----EEILASLEK 285
Cdd:PRK09674 214 EVDLQAGLAQERQLFTLLAAtedrhEGISAFLEK 247
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
47-229 8.64e-18

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 82.24  E-value: 8.64e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   47 VTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVLAVVRSFKDSEsgkectmhKDFFReeyi 126
Cdd:PRK07509  16 VRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEG-GAFCAGLDVKSVASSPGNAV--------KLLFK---- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  127 lnHLIGTLNK-QYVCL------------IDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGsyfLSRLKGN 193
Cdd:PRK07509  83 --RLPGNANLaQRVSLgwrrlpvpviaaLEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAG---TVSLRGL 157
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 25144157  194 LG----MYLALTGYRLLGADAFHAGLATHFVESSELAKLE 229
Cdd:PRK07509 158 VRkdvaRELTYTARVFSAEEALELGLVTHVSDDPLAAALA 197
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
36-234 3.36e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 80.46  E-value: 3.36e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   36 ILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAwNSSSDVDLVILKGSGdKAFCAGGDVLAVVRSfkDSESGKECT 115
Cdd:PRK07659   8 VVVKYEGRVATIMLNRPEALNALDEPMLKELLQALKE-VAESSAHIVVLRGNG-RGFSAGGDIKMMLSS--NDESKFDGV 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  116 MHkdfFREEYILnhLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKG-NL 194
Cdd:PRK07659  84 MN---TISEIVV--TLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGeNK 158
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 25144157  195 GMYLALTGYRLLGADAFHAGLAThFVESSELAKLEKELVN 234
Cdd:PRK07659 159 AKQIIWEGKKLSATEALDLGLID-EVIGGDFQTAAKQKIS 197
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
36-232 4.67e-17

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 80.12  E-value: 4.67e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   36 ILVDTHGSKKVVTLNRPKAlNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDVLAVVRSfkDSESGkect 115
Cdd:PRK03580   5 LHTTRNGSILEITLDRPKA-NAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKFFSAGWDLKAAAEG--EAPDA---- 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  116 mhkDFFREEYI-LNHLIGtLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFL-SRLKGN 193
Cdd:PRK03580  78 ---DFGPGGFAgLTEIFD-LDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLpKRLPPA 153
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 25144157  194 LGMYLALTGYRLLGADAFHAGLATHFVESSELAKLEKEL 232
Cdd:PRK03580 154 IANEMVMTGRRMDAEEALRWGIVNRVVPQAELMDRAREL 192
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
47-226 2.18e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 78.11  E-value: 2.18e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   47 VTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDVlAVVRSFKDSEsgkectmhkDFFREEYI 126
Cdd:PRK06144  21 ITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDI-AQFRAFSTAE---------DAVAYERR 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  127 LNHLIGTLN---KQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMP-ETALG--LFPDVggsyfLSRLKGNLGMY--- 197
Cdd:PRK06144  91 IDRVLGALEqlrVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFPiARTLGncLSMSN-----LARLVALLGAArvk 165
                        170       180       190
                 ....*....|....*....|....*....|.
gi 25144157  198 -LALTGyRLLGAD-AFHAGLATHFVESSELA 226
Cdd:PRK06144 166 dMLFTA-RLLEAEeALAAGLVNEVVEDAALD 195
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
46-215 3.37e-16

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 77.81  E-value: 3.37e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   46 VVTLNRPkALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVLAvvRSFKDSESGkECTMHKDFFREey 125
Cdd:PRK06495  16 VVTLDNP-PVNALSRELRDELIAVFDEISERPDVRVVVLTGAG-KVFCAGADLKG--RPDVIKGPG-DLRAHNRRTRE-- 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  126 iLNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLfpdVGGSYFLSRLKG-NLGMYLALTGYR 204
Cdd:PRK06495  89 -CFHAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL---AGGGKHAMRLFGhSLTRRMMLTGYR 164
                        170
                 ....*....|.
gi 25144157  205 LLGADAFHAGL 215
Cdd:PRK06495 165 VPAAELYRRGV 175
menB TIGR01929
naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, ...
47-242 8.05e-16

naphthoate synthase (dihydroxynaphthoic acid synthetase); This model represents an enzyme, naphthoate synthase (dihydroxynaphthoic acid synthetase), which is involved in the fifth step of the menaquinone biosynthesis pathway. Together with o-succinylbenzoate-CoA ligase (menE: TIGR01923), this enzyme takes 2-succinylbenzoate and converts it into 1,4-di-hydroxy-2-naphthoate. Included above the trusted cutoff are two enzymes from Arabadopsis thaliana and one from Staphylococcus aureus which are identified as putative enoyl-CoA hydratase/isomerases. These enzymes group with the naphthoate synthases when building a tree and when doing BLAST searches. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 200143 [Multi-domain]  Cd Length: 259  Bit Score: 76.43  E-value: 8.05e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157    47 VTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDVLAVVRSFKDSESGKECTMHKDFFReeyi 126
Cdd:TIGR01929  16 ITINRPQVRNAFRPLTVKEIIQALDDAREDPDIGVVILTGAGDKAFCSGGDQKVRGDYGYIDDSGVHRLNVLDVQR---- 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   127 lnhLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKGN-LGMYLALTGYRL 205
Cdd:TIGR01929  92 ---QIRTCPKPVIAMVNGYAIGGGHVLHMMCDLTIAAENARFGQTGPKVGSFDGGYGSSYMARIVGQkKAREIWFLCRQY 168
                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 25144157   206 LGADAFHAGLATHFVessELAKLEKELVNI-KDVTENS 242
Cdd:TIGR01929 169 DAKQALDMGLVNTVV---PLADLEKETVRWcREILQKS 203
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
36-225 5.54e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 74.24  E-value: 5.54e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   36 ILVDTHGSKKVVTLNRPKALNALN-LEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVLAVvRSFKDSESGKEC 114
Cdd:PRK09245   5 LLVERDGHIVTLTMNRPETRNALSdNDAVDALVAACAAINADRSVRAVILTGAG-TAFSSGGNVKDM-RARVGAFGGSPA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  115 TMhkdffREEY---I--LNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSR 189
Cdd:PRK09245  83 DI-----RQGYrhgIqrIPLALYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPR 157
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 25144157  190 LkgnLGM----YLALTGYRLLGADAFHAGLATHFVESSEL 225
Cdd:PRK09245 158 I---IGMaraaEMAFTGDAIDAATALEWGLVSRVVPADQL 194
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
37-234 6.65e-15

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 73.98  E-value: 6.65e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   37 LVDTHGSKKVVTLNRPKALNALNLEMVREFYpklQAW---NSSSDVDLVILKGSGDkAFCAGGDVLAVVR-----SFKDS 108
Cdd:PRK07799   8 LVEQRGHTLIVTMNRPEARNALSTEMLRIMV---DAWdrvDNDPDIRSCILTGAGG-AFCAGMDLKAATKkppgdSFKDG 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  109 EsgkectmhKDFFREEYILNHLigTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPdVGGSYF-L 187
Cdd:PRK07799  84 S--------YDPSRIDALLKGR--RLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFP-MGGSAVrL 152
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 25144157  188 SR-LKGNLGMYLALTGYRLLGADAFHAGLATHFV-ESSELAK-LE-KELVN 234
Cdd:PRK07799 153 VRqIPYTVACDLLLTGRHITAAEAKEIGLIGHVVpDGQALDKaLElAELIN 203
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
30-241 7.85e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 73.97  E-value: 7.85e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   30 AAAKSEILVDTHGSK-KVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDvLAVVRSFKDS 108
Cdd:PRK06210   1 DMAYDAVLYEVADSGvAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAG-RGFCAGAD-MGELQTIDPS 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  109 ESGKECTM-------HKDFFREEyilnHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDV 181
Cdd:PRK06210  79 DGRRDTDVrpfvgnrRPDYQTRY----HFLTALRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEH 154
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 25144157  182 GGSYFLSRLKGN-LGMYLALTGYRLLGADAFHAGLATHFVESSELakLEKELVNIKDVTEN 241
Cdd:PRK06210 155 GISWILPRLVGHaNALDLLLSARTFYAEEALRLGLVNRVVPPDEL--MERTLAYAEDLARN 213
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
34-229 1.12e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 73.22  E-value: 1.12e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   34 SEILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVLAVvrsFKDSESGKE 113
Cdd:PRK05870   3 DPVLLDVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAG-KAFCAGADLTAL---GAAPGRPAE 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  114 CTMHK---DFFReeyilnhlIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRL 190
Cdd:PRK05870  79 DGLRRiydGFLA--------VASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRA 150
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 25144157  191 KG-NLGMYLALTGYRLLGADAFHAGLATHFVESSELAKLE 229
Cdd:PRK05870 151 VGpQVARAALLFGMRFDAEAAVRHGLALMVADDPVAAALE 190
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
38-227 1.62e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 72.74  E-value: 1.62e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   38 VDTHGSKKVVTLNRPKALNALN---LEMVREFYPKLQAwnsssDVDLVILKGSGDKaFCAGGDvLAVVRSFKDSESGKEC 114
Cdd:PRK08150   6 YELDGGVATIGLNRPAKRNALNdglIAALRAAFARLPE-----GVRAVVLHGEGDH-FCAGLD-LSELRERDAGEGMHHS 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  115 TM-HKDFFREEYILNHLIGTLNkqyvclidGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKGN 193
Cdd:PRK08150  79 RRwHRVFDKIQYGRVPVIAALH--------GAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGV 150
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 25144157  194 LGMY-LALTGYRLLGADAFHAGLATHFVESSE-LAK 227
Cdd:PRK08150 151 ARMTdMMLTGRVYDAQEGERLGLAQYLVPAGEaLDK 186
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
49-224 1.67e-14

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 73.01  E-value: 1.67e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   49 LNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKaFCAGGDVLAVVRSFKDSESGKECTMHKDFFREEYILN 128
Cdd:PLN02664  23 LNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAGDH-FCSGIDLKTLNSISEQSSSGDRGRSGERLRRKIKFLQ 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  129 HLIGTLN---KQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGsyfLSRLKGNLG----MYLALT 201
Cdd:PLN02664 102 DAITAIEqcrKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGT---LQRLPSIVGygnaMELALT 178
                        170       180
                 ....*....|....*....|...
gi 25144157  202 GYRLLGADAFHAGLATHFVESSE 224
Cdd:PLN02664 179 GRRFSGSEAKELGLVSRVFGSKE 201
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
34-224 1.80e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 72.72  E-value: 1.80e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   34 SEILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVLAVVRSFKDSESGKE 113
Cdd:PRK08252   3 DEVLVERRGRVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAG-GTFCAGMDLKAFARGERPSIPGRG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  114 ctmhkdffreeyilnhlIGTLN-----KQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFL- 187
Cdd:PRK08252  82 -----------------FGGLTerpprKPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLp 144
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 25144157  188 SRLKGNLGMYLALTGYRLLGADAFHAGLATHFVESSE 224
Cdd:PRK08252 145 RRIPYHIAMELALTGDMLTAERAHELGLVNRLTEPGQ 181
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
35-233 2.55e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 72.08  E-value: 2.55e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   35 EILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVLAVVRSFK--DSESgk 112
Cdd:PRK07260   3 HIIYEVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANG-KVFSVGGDLVEMKRAVDedDVQS-- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  113 ectmhkdFFREEYILNHL---IGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSR 189
Cdd:PRK07260  80 -------LVKIAELVNEIsfaIKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTR 152
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 25144157  190 LKG-NLGMYLALTGYRLLGADAFHAGLATHFVESSELAKLEKELV 233
Cdd:PRK07260 153 AIGlNRATHLAMTGEALTAEKALEYGFVYRVAESEKLEKTCEQLL 197
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
34-292 2.68e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 72.34  E-value: 2.68e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   34 SEILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDkAFCAGGD--VLAVVRSFKDSEsg 111
Cdd:PRK07511   3 AELLSRREGSTLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGAGG-FFCAGGNlnRLLENRAKPPSV-- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  112 kectmhkdffREEYI--LNHLIGTLN---KQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYF 186
Cdd:PRK07511  80 ----------QAASIdgLHDWIRAIRafpKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWF 149
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  187 LSR-LKGNLGMYLALTGYRLLGADAFHAGLATHFVESSE-----LAkLEKELVNIKDVTENSVDEVIRsfepkKIPEFSL 260
Cdd:PRK07511 150 LARaLPRQLATELLLEGKPISAERLHALGVVNRLAEPGQalaeaLA-LADQLAAGSPNALARIKSLIA-----DAPEATL 223
                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 25144157  261 SKNLAQIRDSF-----KAKSVEEILASLEKDGSDWAK 292
Cdd:PRK07511 224 AAQLEAERDHFvaslhHADALEGIAAFLEKRAPDYKR 260
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
47-232 4.04e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 71.63  E-value: 4.04e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   47 VTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDV------LAVVRSFKDSESGKECTMHKdf 120
Cdd:PRK07468  18 LTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAG-KSFCAGGDLgwmraqMTADRATRIEEARRLAMMLK-- 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  121 freeyILNhligTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKGNLGMYLAL 200
Cdd:PRK07468  95 -----ALN----DLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARMGEANARRVFM 165
                        170       180       190
                 ....*....|....*....|....*....|....
gi 25144157  201 TGyRLLGAD-AFHAGLATHFVESSEL-AKLEKEL 232
Cdd:PRK07468 166 SA-RLFDAEeAVRLGLLSRVVPAERLdAAVEAEV 198
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
34-234 4.05e-14

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 71.69  E-value: 4.05e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   34 SEILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSD-VDLVILKGSGdKAFCAGGDVLAVVRSFKDSESGK 112
Cdd:PRK05981   4 KKVTLDFDGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKAeVRCLVLTGAG-RGFCTGANLQGRGSGGRESDSGG 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  113 EC-----TMHKDFFReeyilnhLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFL 187
Cdd:PRK05981  83 DAgaaleTAYHPFLR-------RLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLL 155
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 25144157  188 SRLKGNL-GMYLALTGYRLLGADAFHAGLATHFVESSEL----AKLEKELVN 234
Cdd:PRK05981 156 PRLVGKArAMELSLLGEKLPAETALQWGLVNRVVDDAELmaeaMKLAHELAN 207
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
46-232 4.80e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 71.20  E-value: 4.80e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   46 VVTLNRPKAlNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVlavvRSFKDSESGKECTMHKD-----F 120
Cdd:PRK07658  14 VITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIHGEG-RFFSAGADI----KEFTSVTEAEQATELAQlgqvtF 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  121 FREEyilnhligTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKGNLGMY-LA 199
Cdd:PRK07658  88 ERVE--------KFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALeMM 159
                        170       180       190
                 ....*....|....*....|....*....|...
gi 25144157  200 LTGYRLLGADAFHAGLATHFVESSELAKLEKEL 232
Cdd:PRK07658 160 LTSEPITGAEALKWGLVNGVFPEETLLDDAKKL 192
PLN02888 PLN02888
enoyl-CoA hydratase
36-232 1.57e-13

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 70.17  E-value: 1.57e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   36 ILVD-THGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVLAVVRSFKDSESGKEc 114
Cdd:PLN02888  11 ILVPkSRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSG-RAFCSGVDLTAAEEVFKGDVKDVE- 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  115 tmHKDFFREEYILNHLIGTLNkqyvclidGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKG-N 193
Cdd:PLN02888  89 --TDPVAQMERCRKPIIGAIN--------GFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGaN 158
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 25144157  194 LGMYLALTGYRLLGADAFHAGLATHFVESSELAKLEKEL 232
Cdd:PLN02888 159 RAREVSLTAMPLTAETAERWGLVNHVVEESELLKKAREV 197
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
35-224 3.04e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 69.18  E-value: 3.04e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   35 EILVDTHGSKKVVTLNRPKAlNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDvlavVRSFKDSESGKEC 114
Cdd:PRK09076   4 ELDLEIDGHVAILTLNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGAD----LNLFADGDKAVAR 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  115 TMHKDF---------FREEYIlnhligtlnkqyvCLIDGIVMGGG--CGLSVNgrFRVATEKTMLAMPETALGLFPDVGG 183
Cdd:PRK09076  79 EMARRFgeafealsaFRGVSI-------------AAINGYAMGGGleCALACD--IRIAEEQAQMALPEASVGLLPCAGG 143
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 25144157  184 SYFLSRLKG-NLGMYLALTGYRLLGADAFHAGLATHFVESSE 224
Cdd:PRK09076 144 TQNLPWLVGeGWAKRMILCGERVDAATALRIGLVEEVVEKGE 185
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
36-226 2.54e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 66.48  E-value: 2.54e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   36 ILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSdVDLVILKGSGdKAFCAGGDVlavvrSFKDSESGKECT 115
Cdd:PRK08140   6 ILLAIEAGVATLTLNRPDKLNSFTREMHRELREALDQVEDDG-ARALLLTGAG-RGFCAGQDL-----ADRDVTPGGAMP 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  116 MHKDFFREEYilNHLIGT---LNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKG 192
Cdd:PRK08140  79 DLGESIETFY--NPLVRRlraLPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVG 156
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 25144157  193 NL-GMYLALTGYRLLGADAFHAGLATHFVESSELA 226
Cdd:PRK08140 157 MArALGLALLGEKLSAEQAEQWGLIWRVVDDAALA 191
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
47-225 7.09e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 65.41  E-value: 7.09e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   47 VTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVLAVVRSFkdsesGKECTMHKDFFREEYI 126
Cdd:PRK08260  17 ITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAG-RAFCAGADLSAGGNTF-----DLDAPRTPVEADEEDR 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  127 LNHL--------------IGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLkg 192
Cdd:PRK08260  91 ADPSddgvrdgggrvtlrIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPRL-- 168
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 25144157  193 nLGMYLAL----TGyRLLGAD-AFHAGLATHFVESSEL 225
Cdd:PRK08260 169 -VGLQTALewvySG-RVFDAQeALDGGLVRSVHPPDEL 204
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
24-226 2.61e-11

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 63.42  E-value: 2.61e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   24 MSFSVSAAAKSEILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVlavvr 103
Cdd:PRK08139   1 MMAPAAATEAPLLLREDRDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAG-KAFCAGHDL----- 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  104 sfkdsesgKECTMH--KDFFREEY----ILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGL 177
Cdd:PRK08139  75 --------KEMRAArgLAYFRALFarcsRVMQAIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGL 146
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 25144157  178 F---PDVGgsyfLSRlkgNLG----MYLALTGYRLLGADAFHAGLATHFVESSELA 226
Cdd:PRK08139 147 FcstPMVA----LSR---NVPrkqaMEMLLTGEFIDAATAREWGLVNRVVPADALD 195
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
24-221 2.67e-11

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 65.24  E-value: 2.67e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157    24 MSFSVSAAAKSEILVDTHGSKKVVTLNRPKA-LNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDVlAVV 102
Cdd:TIGR02441   3 FSTSAALMARTHRHYEVKGDVAVVKIDSPNSkVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADI-QMI 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   103 RSFKDSESGKECTM--HKDFFREEyilnhligTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATE--KTMLAMPETALGLF 178
Cdd:TIGR02441  82 AACKTAQEVTQLSQegQEMFERIE--------KSQKPIVAAISGSCLGGGLELALACHYRIATKdrKTLLGLPEVMLGLL 153
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 25144157   179 PDVGGSYFLSRLKG-NLGMYLALTGYRLLGADAFHAGLATHFVE 221
Cdd:TIGR02441 154 PGAGGTQRLPKLTGvPAALDMMLTGKKIRADRAKKMGIVDQLVD 197
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
38-215 1.23e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 58.45  E-value: 1.23e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   38 VDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVLAVVRSFKDSESGKECTMH 117
Cdd:PRK06142  10 VELADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSG-KHFSYGIDLPAMAGVFGQLGKDGLARPR 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  118 KDFFREeyILNhLIGTLN------KQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLK 191
Cdd:PRK06142  89 TDLRRE--ILR-LQAAINavadcrKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPRII 165
                        170       180
                 ....*....|....*....|....*.
gi 25144157  192 GNlGMY--LALTGYRLLGADAFHAGL 215
Cdd:PRK06142 166 GD-GHLreLALTGRDIDAAEAEKIGL 190
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
47-192 1.63e-09

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 59.49  E-value: 1.63e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   47 VTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKgSGDKAFCAGGDVLAVVRSFKDSEsgkectmhkdffreEYI 126
Cdd:PRK11730  20 LVFDAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLT-SAKDAFIVGADITEFLSLFAAPE--------------EEL 84
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 25144157  127 LNHLIGTlNKQY----------VCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKG 192
Cdd:PRK11730  85 SQWLHFA-NSIFnrledlpvptVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIG 159
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
38-217 2.67e-09

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 57.38  E-value: 2.67e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   38 VDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVLAVVRSFKDSESgkectMH 117
Cdd:PRK07827  10 YAVDGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTG-GTFCAGADLSEAGGGGGDPYD-----AA 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  118 KDFFREEYILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKGN-LGM 196
Cdd:PRK07827  84 VARAREMTALLRAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRaAAR 163
                        170       180
                 ....*....|....*....|.
gi 25144157  197 YLaLTGYRLLGADAFHAGLAT 217
Cdd:PRK07827 164 YY-LTGEKFGAAEAARIGLVT 183
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
46-233 7.25e-09

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 57.60  E-value: 7.25e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   46 VVTLNRP-KALNALNLEMVREFYPKLQAWNSSSDVD-LVILKGSGDkAFCAGGDV--LAVVRSFKDSESGKEcTMHKDFF 121
Cdd:PRK11154  18 VITIDVPgEKMNTLKAEFAEQVRAILKQLREDKELKgVVFISGKPD-NFIAGADInmLAACKTAQEAEALAR-QGQQLFA 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  122 ReeyilnhlIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVAT--EKTMLAMPETALGLFPDVGGSYFLSRLKGNL-GMYL 198
Cdd:PRK11154  96 E--------IEALPIPVVAAIHGACLGGGLELALACHYRVCTddPKTVLGLPEVQLGLLPGSGGTQRLPRLIGVStALDM 167
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 25144157  199 ALTGYRLLGADAFHAGLATHFVESSELAKLEKELV 233
Cdd:PRK11154 168 ILTGKQLRAKQALKLGLVDDVVPHSILLEVAVELA 202
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
46-225 7.76e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 55.81  E-value: 7.76e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   46 VVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDVLAVVRSfkDSESGkectmhkdffrEEY 125
Cdd:PRK06143  19 TLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATL--DQASA-----------EAF 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  126 I--LNHLIGTLNKQYVCLI---DGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLfPDVGGSYFLSRLKGNL-GMYLA 199
Cdd:PRK06143  86 IsrLRDLCDAVRHFPVPVIariPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGI-PSVIHAALLPRLIGWArTRWLL 164
                        170       180
                 ....*....|....*....|....*.
gi 25144157  200 LTGYRLLGADAFHAGLATHFVESSEL 225
Cdd:PRK06143 165 LTGETIDAAQALAWGLVDRVVPLAEL 190
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
47-226 1.02e-08

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 55.74  E-value: 1.02e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   47 VTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDkAFCAGGDVLAVVrsfkdsesGKECTM----HKDFFR 122
Cdd:PRK08258  30 ITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGG-NFCSGGDVHEII--------GPLTKMdmpeLLAFTR 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  123 eeyilnhLIGTLNK-------QYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLF-PDVGGSYFLSRLKGnL 194
Cdd:PRK08258 101 -------MTGDLVKamracpqPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRVGLAgADMGACALLPRIIG-Q 172
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 25144157  195 G--MYLALTGyRLLGADAFHA-GLATHFVESSELA 226
Cdd:PRK08258 173 GraSELLYTG-RSMSAEEGERwGFFNRLVEPEELL 206
PLN02921 PLN02921
naphthoate synthase
47-192 3.55e-08

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 54.41  E-value: 3.55e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   47 VTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDvlAVVRSfKDSESGKEctmhkDFFReeyi 126
Cdd:PLN02921  80 ITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGD--QAVRG-KDGYVGPD-----DAGR---- 147
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25144157  127 LNHL-----IGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFpDVG-GSYFLSRLKG 192
Cdd:PLN02921 148 LNVLdlqiqIRRLPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSF-DAGyGSSIMARLVG 218
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
34-159 4.24e-08

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 53.74  E-value: 4.24e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   34 SEILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDKAFCAGGDvlAVVRS---FKDsES 110
Cdd:PRK07396  13 EDILYKSADGIAKITINRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKAFCSGGD--QKVRGyggYVD-DD 89
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25144157  111 GkectMHKdffreeyiLN-----HLIGTLNKQYVCLIDGIVMGGG------CGLSV---NGRF 159
Cdd:PRK07396  90 G----VPR--------LNvldlqRLIRTCPKPVIAMVAGYAIGGGhvlhlvCDLTIaadNAIF 140
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
46-216 4.97e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 53.49  E-value: 4.97e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   46 VVTLNRPKALNALNLEMVREFYPKLQAwNSSSDVDLVILKGSGdKAFCAGGDVLAVVrsFKDsesgkectmhkDFFREEY 125
Cdd:PRK07854  12 TIELQRPERRNALNAELCEELREAVRK-AVDESARAIVLTGQG-TVFCAGADLSGDV--YAD-----------DFPDALI 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  126 ILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDvggSYFLSRLKGNLGMYLA----LT 201
Cdd:PRK07854  77 EMLHAIDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALD---NWTIRRLSSLVGGGRAramlLG 153
                        170
                 ....*....|....*
gi 25144157  202 GYRLLGADAFHAGLA 216
Cdd:PRK07854 154 AEKLTAEQALATGMA 168
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
36-225 9.50e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 52.49  E-value: 9.50e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   36 ILVD---THGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSgDKAFCAG---GDVLAVVRSfkDSE 109
Cdd:PRK06023   5 ILVErpgAHPGVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGT-EGCFSAGndmQDFLAAAMG--GTS 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  110 SGKECTmhkDFFREeyilnhlIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSR 189
Cdd:PRK06023  82 FGSEIL---DFLIA-------LAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPR 151
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 25144157  190 LKGNLGMY--LALtGYRLLGADAFHAGLATHFVESSEL 225
Cdd:PRK06023 152 LMGHQRAFalLAL-GEGFSAEAAQEAGLIWKIVDEEAV 188
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
49-235 1.99e-07

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 51.73  E-value: 1.99e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   49 LNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDvLAVVRSFKDSESGKECTMHKDFFREEYILN 128
Cdd:PRK05674  21 LSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRG-RHFSAGAD-LAWMQQSADLDYNTNLDDARELAELMYNLY 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  129 HL-IGTLnkqyvCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKGNLGMYLALTGYRLLG 207
Cdd:PRK05674  99 RLkIPTL-----AVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISPFVVKAIGERAARRYALTAERFDG 173
                        170       180
                 ....*....|....*....|....*....
gi 25144157  208 ADAFHAGLATHFVESSEL-AKLEKELVNI 235
Cdd:PRK05674 174 RRARELGLLAESYPAAELeAQVEAWIANL 202
MenB COG0447
1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1, ...
47-159 3.91e-07

1,4-Dihydroxy-2-naphthoyl-CoA synthase [Coenzyme transport and metabolism]; 1,4-Dihydroxy-2-naphthoyl-CoA synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440216  Cd Length: 281  Bit Score: 50.97  E-value: 3.91e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  47 VTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDK-----AFCAGGDvlAVVRS---FKDSESGKEctMHk 118
Cdd:COG0447  31 IAINRPEVRNAFRPETVDELYDALDHAREDPDVGVVLLTGNGPSkdggwAFCSGGD--QRVRGrggYVYEDGVGR--LN- 105
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 25144157 119 dffreeyILN--HLIGTLNKQYVCLIDGIVMGGG------CGLSV---NGRF 159
Cdd:COG0447 106 -------ILEvqRLIRFMPKPVIAMVAGWAIGGGhvlhvvCDLTIaseNARF 150
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
47-229 6.48e-07

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 50.39  E-value: 6.48e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   47 VTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDkAFCAGGDvlaVVRSFKDSESGKECTMHKdFFREEYI 126
Cdd:PRK09120  21 VTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLTGAGD-AWSAGMD---LKEYFRETDAQPEILQER-IRREAYG 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  127 LNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKGNL-GMYLALTGYRL 205
Cdd:PRK09120  96 WWRRLRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTVGHRdALYYIMTGETF 175
                        170       180
                 ....*....|....*....|....
gi 25144157  206 LGADAFHAGLAThfvESSELAKLE 229
Cdd:PRK09120 176 TGRKAAEMGLVN---ESVPLAQLR 196
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
34-225 7.47e-07

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 50.03  E-value: 7.47e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   34 SEILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSsDVDLVILK-GSGDKAFCAGGDVLAVVRSFKDSESgk 112
Cdd:PRK11423   4 QYVNVVTINKIATITFNNPAKRNALSKVLIDDLMQALSDLNRP-EIRVVILRaPSGSKVWSAGHDIHELPSGGRDPLS-- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  113 ectmHKDFFReeyILNHLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGsyfLSRLKG 192
Cdd:PRK11423  81 ----YDDPLR---QILRMIQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSG---ILNFTN 150
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 25144157  193 NLGMYLA----LTGYRLLGADAFHAGLATHFVESSEL 225
Cdd:PRK11423 151 DAGFHIVkemfFTASPITAQRALAVGILNHVVEVEEL 187
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
46-225 7.68e-06

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 47.14  E-value: 7.68e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   46 VVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDvlavVRSFKDSESGKECTMHKDFFREEY 125
Cdd:PRK05864  22 LITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAG-RGFSSGAD----HKSAGVVPHVEGLTRPTYALRSME 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  126 ILNHLIGTLNKQY---VCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLF-PDVGGSYFLSRLKGNLGMY-LAL 200
Cdd:PRK05864  97 LLDDVILALRRLHqpvIAAVNGPAIGGGLCLALAADIRVASSSAYFRAAGINNGLTaSELGLSYLLPRAIGSSRAFeIML 176
                        170       180
                 ....*....|....*....|....*
gi 25144157  201 TGYRLLGADAFHAGLATHFVESSEL 225
Cdd:PRK05864 177 TGRDVDAEEAERIGLVSRQVPDEQL 201
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
47-234 1.28e-05

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 46.57  E-value: 1.28e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   47 VTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVLAVVRSFKDSESG--------------- 111
Cdd:PRK08272  23 ITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAG-KGFCAGYDLSAYAEGSSSGGGGgaypgkrqavnhlpd 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  112 ------KECTMHKDFFREEYILNHligtLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGgsY 185
Cdd:PRK08272 102 dpwdpmIDYQMMSRFVRGFMSLWH----AHKPTVAKVHGYCVAGGTDIALHCDQVIAADDAKIGYPPTRVWGVPATG--M 175
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 25144157  186 FLSRLKGNLGMYLALTGYRLLGADAFHAGLATHFVESSELAKLEKELVN 234
Cdd:PRK08272 176 WAYRLGPQRAKRLLFTGDCITGAQAAEWGLAVEAVPPEELDERTERLVE 224
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
47-155 1.84e-05

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 46.17  E-value: 1.84e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   47 VTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDK------AFCAGGDVLAVVRS-FKDSESGKECTMHKD 119
Cdd:PRK08321  38 IAFDRPEVRNAFRPHTVDELYRALDHARMSPDVGCVLLTGNGPSpkdggwAFCSGGDQRIRGRDgYQYAEGDEADTVDPA 117
                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 25144157  120 FFREEYIL--NHLIGTLNKQYVCLIDGIVMGGGCGLSV 155
Cdd:PRK08321 118 RAGRLHILevQRLIRFMPKVVIAVVPGWAAGGGHSLHV 155
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
36-97 1.12e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 43.41  E-value: 1.12e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25144157   36 ILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGD 97
Cdd:PRK08290   6 VRYEVAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAG-KHFSAGHD 66
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
36-235 1.24e-04

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 43.41  E-value: 1.24e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   36 ILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDVLAVVRSFKDS------- 108
Cdd:PRK12478   7 LLYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAG-RAFSGGYDFGGGFQHWGEAmmtdgrw 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  109 ESGKECTMHKDffREEYILNHL--IGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPetalglFPDVGGSY- 185
Cdd:PRK12478  86 DPGKDFAMVTA--RETGPTQKFmaIWRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTP------YSRMWGAYl 157
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 25144157  186 ---FLSRLKGNLGMYLALTGYRLLGADAFHAGLAThfvESSELAKLEKELVNI 235
Cdd:PRK12478 158 tgmWLYRLSLAKVKWHSLTGRPLTGVQAAEAELIN---EAVPFERLEARVAEV 207
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
47-117 1.32e-04

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 43.09  E-value: 1.32e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 25144157   47 VTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGdKAFCAGGDvLAVVRSFKDSESGKECTMH 117
Cdd:PRK07327  25 IVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEG-KAFSAGGD-LALVEEMADDFEVRARVWR 93
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
24-225 2.39e-04

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 42.56  E-value: 2.39e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   24 MSFSVSAAAKSEILVDTH-GSKKVVTLNRpKALNALNLEMVREFYPKLQAWNSSSDVDLVILkGSGDK--AFCAGGDvLA 100
Cdd:PLN03214   1 MPAPSPPGATPGVRVDRRpGGIAVVWLAK-EPVNSMTLAMWRSLDDALTALENDPTVRGVVF-ASGLRrdVFTAGND-IA 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  101 VVRSFKDSEsgkecTMHKDFFR-EEYILNHLIGTlNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGL-F 178
Cdd:PLN03214  78 ELYAPKTSA-----ARYAEFWLtQTTFLVRLLRS-RLATVCAIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIpV 151
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 25144157  179 PDVGGSYFLSRLKGNLGMYLALTGYRLLG-ADAFHAGLATHFVESSEL 225
Cdd:PLN03214 152 PKFWARLFMGRVIDRKVAESLLLRGRLVRpAEAKQLGLIDEVVPAAAL 199
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
36-101 5.56e-04

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 41.04  E-value: 5.56e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 25144157   36 ILVDTHGSKKVVTLNRPKALNALNLEMVREFYPKLQAWNSSSDVDLVILKGSGDkAFCAGGDVLAV 101
Cdd:PRK08259   5 VRVERNGPVTTVILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGG-TFCAGADLKAV 69
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
49-192 1.26e-03

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 39.82  E-value: 1.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   49 LNRPKAlNALNLEMVREFYPKLQAWNSSSDVDLVILKGsGDKAFCAGGDVLAVvRSFKDSESGKectmhKDFFREEYIln 128
Cdd:PRK05869  23 LSRPPT-NALTRQVYREIVAAANELGRRDDVAAVILYG-GHEIFSAGDDMPEL-RTLSAQEADT-----AARVRQQAV-- 92
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 25144157  129 HLIGTLNKQYVCLIDGIVMGGGCGLSVNGRFRVATEKTMLAMPETALGLFPDVGGSYFLSRLKG 192
Cdd:PRK05869  93 DAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAG 156
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
59-221 2.78e-03

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 39.12  E-value: 2.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157   59 NLEMVREF-----YPKLQAWNSSSDVDLVILKGSGDKAFCAGGDvLAVVRSF---KDSES----GKECT--MHkdffree 124
Cdd:PRK08788  41 NLELLDDImnlqrAIRQRLDDSGLPVDFWVLASDVPGVFNLGGD-LALFAELiraGDRDAllayARACVdgVH------- 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25144157  125 yiLNHLIGTLNKQYVCLIDGIVMGGG--CGLSVNgrFRVATEKTMLAMPETALGLFPDVGGSYFLSRlkgNLGMYLA--- 199
Cdd:PRK08788 113 --AFHRGFGAGAISIALVQGDALGGGfeAALSHH--TIIAERGAKMGFPEILFNLFPGMGAYSFLAR---RVGPKLAeel 185
                        170       180
                 ....*....|....*....|....
gi 25144157  200 -LTGyRLLGADAFHA-GLATHFVE 221
Cdd:PRK08788 186 iLSG-KLYTAEELHDmGLVDVLVE 208
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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