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Conserved domains on  [gi|24647611|ref|NP_732207|]
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cheerio, isoform B [Drosophila melanogaster]

Protein Classification

IG_FLMN and Filamin domain-containing protein( domain architecture ID 12215647)

IG_FLMN and Filamin domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 433-521 9.66e-31

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 115.78  E-value: 9.66e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611    433 HLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPS--KADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHI 510
Cdd:smart00557   2 SKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHI 81

                           90
                   ....*....|.
gi 24647611    511 PDSPFKVYVSP 521
Cdd:smart00557  82 PGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 239-328 4.07e-30

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 114.24  E-value: 4.07e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611    239 AKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPS--KAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHH 316
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|..
gi 24647611    317 VEGSPFTVKVAG 328
Cdd:smart00557  81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 58-145 4.19e-29

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 111.16  E-value: 4.19e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611     58 YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPS--KADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIK 135
Cdd:smart00557   3 KVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIP 82

                           90
                   ....*....|
gi 24647611    136 GSPYFAKITG 145
Cdd:smart00557  83 GSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 621-709 1.59e-23

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 95.36  E-value: 1.59e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611    621 PAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAVSIDGPS--KVAMDCTEVEEG-YKVRYTPLLPGEHYITVKYNNMH 697
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGtYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|..
gi 24647611    698 IVGSPFKVNATG 709
Cdd:smart00557  81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 749-838 4.17e-23

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 94.21  E-value: 4.17e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611    749 ASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGEEH 828
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|
gi 24647611    829 IPGSPFQIDV 838
Cdd:smart00557  81 IPGSPFTVKV 90
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 526-615 4.06e-19

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 82.65  E-value: 4.06e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611    526 AHKLEVQQFPQGNIQADAPYQFMVRKNGA-KGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVH 604
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|.
gi 24647611    605 IPDSPFRIKVG 615
Cdd:smart00557  81 IPGSPFTVKVG 91
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 2-52 2.27e-14

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


:

Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 69.17  E-value: 2.27e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 24647611      2 PSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVD 52
Cdd:smart00557  41 PSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91
Filamin pfam00630
Filamin/ABP280 repeat;
372-420 2.70e-11

Filamin/ABP280 repeat;


:

Pssm-ID: 395505  Cd Length: 89  Bit Score: 60.38  E-value: 2.70e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 24647611   372 VTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPF 420
Cdd:pfam00630  40 VTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
 
Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 433-521 9.66e-31

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 115.78  E-value: 9.66e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611    433 HLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPS--KADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHI 510
Cdd:smart00557   2 SKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHI 81

                           90
                   ....*....|.
gi 24647611    511 PDSPFKVYVSP 521
Cdd:smart00557  82 PGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 239-328 4.07e-30

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 114.24  E-value: 4.07e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611    239 AKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPS--KAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHH 316
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|..
gi 24647611    317 VEGSPFTVKVAG 328
Cdd:smart00557  81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 58-145 4.19e-29

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 111.16  E-value: 4.19e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611     58 YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPS--KADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIK 135
Cdd:smart00557   3 KVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIP 82

                           90
                   ....*....|
gi 24647611    136 GSPYFAKITG 145
Cdd:smart00557  83 GSPFTVKVGP 92
Filamin pfam00630
Filamin/ABP280 repeat;
236-323 6.65e-24

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 96.20  E-value: 6.65e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611   236 VGDAKKVKVSGTGLKEGQTHADNIFSVDTRNAGfGGLSVSIEGPS--KAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFA 313
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                          90
                  ....*....|
gi 24647611   314 DHHVEGSPFT 323
Cdd:pfam00630  80 GQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 621-709 1.59e-23

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 95.36  E-value: 1.59e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611    621 PAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAVSIDGPS--KVAMDCTEVEEG-YKVRYTPLLPGEHYITVKYNNMH 697
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGtYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|..
gi 24647611    698 IVGSPFKVNATG 709
Cdd:smart00557  81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 749-838 4.17e-23

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 94.21  E-value: 4.17e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611    749 ASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGEEH 828
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|
gi 24647611    829 IPGSPFQIDV 838
Cdd:smart00557  81 IPGSPFTVKV 90
Filamin pfam00630
Filamin/ABP280 repeat;
435-516 5.08e-22

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 90.81  E-value: 5.08e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611   435 VKAGGSGLERGVVGEAAEFNVWTREAGGGsLAISVEGPS--KADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPD 512
Cdd:pfam00630   7 VKASGPGLEPGVVGKPAEFTVDTRDAGGE-GEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85


                  ....
gi 24647611   513 SPFK 516
Cdd:pfam00630  86 SPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
59-139 6.83e-21

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 87.73  E-value: 6.83e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611    59 VTAYGPGLTHGVTGEPANFTISTKGASaGGLTMAVEGPS--KADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKG 136
Cdd:pfam00630   7 VKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85


                  ...
gi 24647611   137 SPY 139
Cdd:pfam00630  86 SPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 526-615 4.06e-19

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 82.65  E-value: 4.06e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611    526 AHKLEVQQFPQGNIQADAPYQFMVRKNGA-KGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVH 604
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|.
gi 24647611    605 IPDSPFRIKVG 615
Cdd:smart00557  81 IPGSPFTVKVG 91
Filamin pfam00630
Filamin/ABP280 repeat;
618-704 9.39e-19

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 81.57  E-value: 9.39e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611   618 VADPAAVHASGNGLDEVKTGHKADFIINTCNAGvGTLAVSIDGPS--KVAMDCTEVEEG-YKVRYTPLLPGEHYITVKYN 694
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGtYTVSYTPTEPGDYTVSVKFN 79

                          90
                  ....*....|
gi 24647611   695 NMHIVGSPFK 704
Cdd:pfam00630  80 GQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
523-611 2.86e-15

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 71.55  E-value: 2.86e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611   523 AGDAHKLEVQQFPQGNIQADAPYQFMVRKNGAKGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNG 602
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80


                  ....*....
gi 24647611   603 VHIPDSPFR 611
Cdd:pfam00630  81 QHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
747-834 1.53e-14

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 69.63  E-value: 1.53e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611   747 SDASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILyVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGE 826
Cdd:pfam00630   2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGEGE-VEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80


                  ....*...
gi 24647611   827 EHIPGSPF 834
Cdd:pfam00630  81 QHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 2-52 2.27e-14

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 69.17  E-value: 2.27e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 24647611      2 PSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVD 52
Cdd:smart00557  41 PSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91
Filamin pfam00630
Filamin/ABP280 repeat;
372-420 2.70e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 60.38  E-value: 2.70e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 24647611   372 VTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPF 420
Cdd:pfam00630  40 VTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
2-48 5.56e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 59.61  E-value: 5.56e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 24647611     2 PSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFK 48
Cdd:pfam00630  43 PDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
 
Name Accession Description Interval E-value
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 433-521 9.66e-31

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 115.78  E-value: 9.66e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611    433 HLVKAGGSGLERGVVGEAAEFNVWTREAGGGSLAISVEGPS--KADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHI 510
Cdd:smart00557   2 SKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHI 81

                           90
                   ....*....|.
gi 24647611    511 PDSPFKVYVSP 521
Cdd:smart00557  82 PGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 239-328 4.07e-30

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 114.24  E-value: 4.07e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611    239 AKKVKVSGTGLKEGQTHADNIFSVDTRNAGFGGLSVSIEGPS--KAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFADHH 316
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|..
gi 24647611    317 VEGSPFTVKVAG 328
Cdd:smart00557  81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 58-145 4.19e-29

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 111.16  E-value: 4.19e-29
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611     58 YVTAYGPGLTHGVTGEPANFTISTKGASAGGLTMAVEGPS--KADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIK 135
Cdd:smart00557   3 KVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIP 82

                           90
                   ....*....|
gi 24647611    136 GSPYFAKITG 145
Cdd:smart00557  83 GSPFTVKVGP 92
Filamin pfam00630
Filamin/ABP280 repeat;
236-323 6.65e-24

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 96.20  E-value: 6.65e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611   236 VGDAKKVKVSGTGLKEGQTHADNIFSVDTRNAGfGGLSVSIEGPS--KAEIQCTDKDDGTLNISYKPTEPGYYIVNLKFA 313
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFN 79

                          90
                  ....*....|
gi 24647611   314 DHHVEGSPFT 323
Cdd:pfam00630  80 GQHIPGSPFK 89
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 621-709 1.59e-23

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 95.36  E-value: 1.59e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611    621 PAAVHASGNGLDEVKTGHKADFIINTCNAGVGTLAVSIDGPS--KVAMDCTEVEEG-YKVRYTPLLPGEHYITVKYNNMH 697
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSgkKVPVEVKDNGDGtYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|..
gi 24647611    698 IVGSPFKVNATG 709
Cdd:smart00557  81 IPGSPFTVKVGP 92
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 749-838 4.17e-23

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 94.21  E-value: 4.17e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611    749 ASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILYVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGEEH 828
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAGGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|
gi 24647611    829 IPGSPFQIDV 838
Cdd:smart00557  81 IPGSPFTVKV 90
Filamin pfam00630
Filamin/ABP280 repeat;
435-516 5.08e-22

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 90.81  E-value: 5.08e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611   435 VKAGGSGLERGVVGEAAEFNVWTREAGGGsLAISVEGPS--KADIEFKDRKDGSCDVSYKVTEPGEYRVGLKFNDRHIPD 512
Cdd:pfam00630   7 VKASGPGLEPGVVGKPAEFTVDTRDAGGE-GEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85


                  ....
gi 24647611   513 SPFK 516
Cdd:pfam00630  86 SPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
59-139 6.83e-21

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 87.73  E-value: 6.83e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611    59 VTAYGPGLTHGVTGEPANFTISTKGASaGGLTMAVEGPS--KADINYHDNKDGTVSVQYLPTAPGEYQVSVRFGDKHIKG 136
Cdd:pfam00630   7 VKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPG 85


                  ...
gi 24647611   137 SPY 139
Cdd:pfam00630  86 SPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 526-615 4.06e-19

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 82.65  E-value: 4.06e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611    526 AHKLEVQQFPQGNIQADAPYQFMVRKNGA-KGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNGVH 604
Cdd:smart00557   1 ASKVKASGPGLEKGVVGEPAEFTVDTRDAgGGELEVEVTGPSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEH 80

                           90
                   ....*....|.
gi 24647611    605 IPDSPFRIKVG 615
Cdd:smart00557  81 IPGSPFTVKVG 91
Filamin pfam00630
Filamin/ABP280 repeat;
618-704 9.39e-19

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 81.57  E-value: 9.39e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611   618 VADPAAVHASGNGLDEVKTGHKADFIINTCNAGvGTLAVSIDGPS--KVAMDCTEVEEG-YKVRYTPLLPGEHYITVKYN 694
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAG-GEGEVEVTGPDgsPVPVEVTDNGDGtYTVSYTPTEPGDYTVSVKFN 79

                          90
                  ....*....|
gi 24647611   695 NMHIVGSPFK 704
Cdd:pfam00630  80 GQHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
523-611 2.86e-15

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 71.55  E-value: 2.86e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611   523 AGDAHKLEVQQFPQGNIQADAPYQFMVRKNGAKGELDAKIVAPSGTDDDCFIQVIDGEMYSVRFYPRENGIHAIHVKFNG 602
Cdd:pfam00630   1 AADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGEGEVEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80


                  ....*....
gi 24647611   603 VHIPDSPFR 611
Cdd:pfam00630  81 QHIPGSPFK 89
Filamin pfam00630
Filamin/ABP280 repeat;
747-834 1.53e-14

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 69.63  E-value: 1.53e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24647611   747 SDASKVVSKGMGLKKAYIGKQNQFSISATDAGNNILyVGMYGPKGPCEEFHVKHAGHNNYNVQYLVRDRGQYVLLIKWGE 826
Cdd:pfam00630   2 ADASKVKASGPGLEPGVVGKPAEFTVDTRDAGGEGE-VEVTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNG 80


                  ....*...
gi 24647611   827 EHIPGSPF 834
Cdd:pfam00630  81 QHIPGSPF 88
IG_FLMN smart00557
Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding ...
 2-52 2.27e-14

Filamin-type immunoglobulin domains; These form a rod-like structure in the actin-binding cytoskeleton protein, filamin. The C-terminal repeats of filamin bind beta1-integrin (CD29).


Pssm-ID: 214720 [Multi-domain]  Cd Length: 93  Bit Score: 69.17  E-value: 2.27e-14
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 24647611      2 PSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFKFHVD 52
Cdd:smart00557  41 PSGKKVPVEVKDNGDGTYTVSYTPTEPGDYTVTVKFGGEHIPGSPFTVKVG 91
Filamin pfam00630
Filamin/ABP280 repeat;
372-420 2.70e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 60.38  E-value: 2.70e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 24647611   372 VTSPSNVTEDAEIQEVEDGLYAVHFVPKELGVHTVSVRYSEMHIPGSPF 420
Cdd:pfam00630  40 VTGPDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPF 88
Filamin pfam00630
Filamin/ABP280 repeat;
2-48 5.56e-11

Filamin/ABP280 repeat;


Pssm-ID: 395505  Cd Length: 89  Bit Score: 59.61  E-value: 5.56e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 24647611     2 PSGKVDKPVIQDNRDGTVSVKYDPREEGSHELVVKYNGEPVQGSPFK 48
Cdd:pfam00630  43 PDGSPVPVEVTDNGDGTYTVSYTPTEPGDYTVSVKFNGQHIPGSPFK 89
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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