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Conserved domains on  [gi|45551891|ref|NP_731852|]
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flyers-cup, isoform A [Drosophila melanogaster]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
101-428 3.26e-40

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 152.78  E-value: 3.26e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 101 ELWKLARKSGTLNLSNKALARVPKRLYDINEADADSKAVNLEQLTIKEEDAWWNQVPLNNLDLSSNTLTHISpKIENLQS 180
Cdd:COG4886  19 ELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLT-DLGDLTN 97

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 181 LTVLTLHDNalvelpPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEFVELNPDISDLHMLEFLDGGHNNI 260
Cdd:COG4886  98 LTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQL 171

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 261 QSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLLRKLDCLYLQHNDILELPEFEGNEA 340
Cdd:COG4886 172 TDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTN 251

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 341 LNELHASNNFIKIIPKamCSNLPHLKILDLRDNKITELPDELCLLRNLNRLDVSNNTISVLPVTLSSLAHLISLQVEGNP 420
Cdd:COG4886 252 LEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLL 329


                ....*...
gi 45551891 421 IKTIRRDI 428
Cdd:COG4886 330 LKGLLVTL 337
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
520-669 4.29e-15

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 78.05  E-value: 4.29e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 520 VVDFARNQLSTLPNGLQHMKDLvTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLNDLPTEFGVLNTLRELNIANNRFP 599
Cdd:COG4886 117 SLDLSGNQLTDLPEELANLTNL-KELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQIT 195

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 600 CIPNCVYELQGLEILIASENHIKMLNVSgLQNMRRLSTLDLRNNDIETVPpILGNLTNITHLELVGNPFR 669
Cdd:COG4886 196 DLPEPLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLT 263
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
101-428 3.26e-40

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 152.78  E-value: 3.26e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 101 ELWKLARKSGTLNLSNKALARVPKRLYDINEADADSKAVNLEQLTIKEEDAWWNQVPLNNLDLSSNTLTHISpKIENLQS 180
Cdd:COG4886  19 ELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLT-DLGDLTN 97

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 181 LTVLTLHDNalvelpPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEFVELNPDISDLHMLEFLDGGHNNI 260
Cdd:COG4886  98 LTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQL 171

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 261 QSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLLRKLDCLYLQHNDILELPEFEGNEA 340
Cdd:COG4886 172 TDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTN 251

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 341 LNELHASNNFIKIIPKamCSNLPHLKILDLRDNKITELPDELCLLRNLNRLDVSNNTISVLPVTLSSLAHLISLQVEGNP 420
Cdd:COG4886 252 LEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLL 329


                ....*...
gi 45551891 421 IKTIRRDI 428
Cdd:COG4886 330 LKGLLVTL 337
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 158-598 1.15e-18

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 90.68  E-value: 1.15e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  158 LNNLDLSSNTLT-HISPKIENLQSLTVLTLHDNALV-ELPPEIGKLEKLVRLNVSHNKLS-QLPRAMYSLPELRHLNISY 234
Cdd:PLN00113 166 LKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLVgQIPRELGQMKSLKWIYLGYNNLSgEIPYEIGGLTSLNHLDLVY 245

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  235 NefvelnpdisdlhmlefldgghNNIQSLPGGIGFLVRLTALLLPYNHIK-ELPPDLVNMRSLQKIDLMHNDLT-SLPED 312
Cdd:PLN00113 246 N----------------------NLTGPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSLSgEIPEL 303

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  313 MGLLRKLDCLYLqhndilelpefegnealnelhASNNFIKIIPKAMCSnLPHLKILDLRDNKIT-ELPDELCLLRNLNRL 391
Cdd:PLN00113 304 VIQLQNLEILHL---------------------FSNNFTGKIPVALTS-LPRLQVLQLWSNKFSgEIPKNLGKHNNLTVL 361

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  392 DVSNNTIS-VLPVTLSSLAHLISLQVEGNPIKT-IRRDILQCGTTRILKtLHDRAVAKAKEEGGGVDDASTSAGISVTRL 469
Cdd:PLN00113 362 DLSTNNLTgEIPEGLCSSGNLFKLILFSNSLEGeIPKSLGACRSLRRVR-LQDNSFSGELPSEFTKLPLVYFLDISNNNL 440

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  470 RGgQMDDG--DIP-------------GNFPDRYKLRHTRTLAVNLEELT-SVPDQVFQIARdegVHVVDFARNQLS-TLP 532
Cdd:PLN00113 441 QG-RINSRkwDMPslqmlslarnkffGGLPDSFGSKRLENLDLSRNQFSgAVPRKLGSLSE---LMQLKLSENKLSgEIP 516

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 45551891  533 NGLQHMKDLVTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLN-DLPTEFGVLNTLRELNIANNRF 598
Cdd:PLN00113 517 DELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSgEIPKNLGNVESLVQVNISHNHL 583
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
520-669 4.29e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 78.05  E-value: 4.29e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 520 VVDFARNQLSTLPNGLQHMKDLvTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLNDLPTEFGVLNTLRELNIANNRFP 599
Cdd:COG4886 117 SLDLSGNQLTDLPEELANLTNL-KELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQIT 195

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 600 CIPNCVYELQGLEILIASENHIKMLNVSgLQNMRRLSTLDLRNNDIETVPpILGNLTNITHLELVGNPFR 669
Cdd:COG4886 196 DLPEPLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLT 263
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 272-426 1.53e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 67.50  E-value: 1.53e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 272 RLTALLLPYNHIKELPpDLVNMRSLQKIDLMHNDLTSLpEDMGLLRKLDCLYLQHNDILELPEFEGNEALNELHASNNFI 351
Cdd:cd21340   3 RITHLYLNDKNITKID-NLSLCKNLKVLYLYDNKITKI-ENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRI 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 352 KII----------------------------PKAMCSNLPHLKILDLRDNKITELpDELCLLRNLNRLDVSNNTIS---V 400
Cdd:cd21340  81 SVVeglenltnleelhienqrlppgekltfdPRSLAALSNSLRVLNISGNNIDSL-EPLAPLRNLEQLDASNNQISdleE 159

                       170       180
                ....*....|....*....|....*.
gi 45551891 401 LPVTLSSLAHLISLQVEGNPIKTIRR 426
Cdd:cd21340 160 LLDLLSSWPSLRELDLTGNPVCKKPK 185
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 585-672 3.72e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 51.33  E-value: 3.72e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 585 LNTLRELNIANNRFP-----CI-PNCVYELQG-LEILIASENHIKmlNVSGLQNMRRLSTLDLRNN---DIETVPPILGN 654
Cdd:cd21340  89 LTNLEELHIENQRLPpgeklTFdPRSLAALSNsLRVLNISGNNID--SLEPLAPLRNLEQLDASNNqisDLEELLDLLSS 166

                        90
                ....*....|....*....
gi 45551891 655 LTNITHLELVGNPF-RQPR 672
Cdd:cd21340 167 WPSLRELDLTGNPVcKKPK 185
LRR_8 pfam13855
Leucine rich repeat;
158-214 2.64e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 45.21  E-value: 2.64e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 45551891   158 LNNLDLSSNTLTHISPKI-ENLQSLTVLTLHDNALVELPPE-IGKLEKLVRLNVSHNKL 214
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
609-668 2.05e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.82  E-value: 2.05e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 45551891   609 QGLEILIASENHIKMLNVSGLQNMRRLSTLDLRNNDIETVPPI-LGNLTNITHLELVGNPF 668
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
493-693 1.01e-03

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 42.38  E-value: 1.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  493 RTLAVNLEELTSVPDQVfqiarDEGVHVVDFARNQLSTLPnglQHMKDLVTELVLSNNVIGYVPQfisqftrisflnlsn 572
Cdd:PRK15370 265 QSLDLFHNKISCLPENL-----PEELRYLSVYDNSIRTLP---AHLPSGITHLNVQSNSLTALPE--------------- 321

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  573 nllndlptefgvlntlrelniannrfpCIPncvyelQGLEILIASENHIKMLNVS---GLQNmrrlstLDLRNNDI---- 645
Cdd:PRK15370 322 ---------------------------TLP------PGLKTLEAGENALTSLPASlppELQV------LDVSKNQItvlp 362

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 45551891  646 ETVPPILGNLtNITHLELVGNPFRQPRHQILMKGTDAIMSYLRDRIPT 693
Cdd:PRK15370 363 ETLPPTITTL-DVSRNALTNLPENLPAALQIMQASRNNLVRLPESLPH 409
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
101-428 3.26e-40

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 152.78  E-value: 3.26e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 101 ELWKLARKSGTLNLSNKALARVPKRLYDINEADADSKAVNLEQLTIKEEDAWWNQVPLNNLDLSSNTLTHISpKIENLQS 180
Cdd:COG4886  19 ELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLT-DLGDLTN 97

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 181 LTVLTLHDNalvelpPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEFVELNPDISDLHMLEFLDGGHNNI 260
Cdd:COG4886  98 LTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQL 171

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 261 QSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLLRKLDCLYLQHNDILELPEFEGNEA 340
Cdd:COG4886 172 TDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTN 251

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 341 LNELHASNNFIKIIPKamCSNLPHLKILDLRDNKITELPDELCLLRNLNRLDVSNNTISVLPVTLSSLAHLISLQVEGNP 420
Cdd:COG4886 252 LEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLL 329


                ....*...
gi 45551891 421 IKTIRRDI 428
Cdd:COG4886 330 LKGLLVTL 337
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
88-414 6.07e-36

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 140.45  E-value: 6.07e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  88 ERSTHEDDQVLTQELWKLARKSGTLNLSNKALARVPKRLYDINEADADSKAVNLEQLTIKEEDAWWNQVPLNNLDLSSNT 167
Cdd:COG4886  45 LLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQ 124

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 168 LTHISPKIENLQSLTVLTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEFVELNPDISDL 247
Cdd:COG4886 125 LTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNL 204

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 248 HMLEFLDGGHNNIQSLPGGIGFLVRLTALLLPYNHIKELpPDLVNMRSLQKIDLMHNDLTSLPEDMGlLRKLDCLYLQHN 327
Cdd:COG4886 205 TNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDL-PELGNLTNLEELDLSNNQLTDLPPLAN-LTNLKTLDLSNN 282

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 328 DI-------LELPEFEGNEALNELHASNNFIKIIPKAMCSNLPHLKILDLRDNKITELPDELCLLRNLNRLDVSNNTISV 400
Cdd:COG4886 283 QLtdlklkeLELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLL 362

                       330
                ....*....|....
gi 45551891 401 LPVTLSSLAHLISL 414
Cdd:COG4886 363 LTLLLTLGLLGLLE 376
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
158-424 6.38e-26

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 110.79  E-value: 6.38e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 158 LNNLDLSSNTLTHISPKIENLQSLTVLTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEF 237
Cdd:COG4886   6 LSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLL 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 238 VELNPDISDLHMLEFLDGGHNNiqslpgGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLLR 317
Cdd:COG4886  86 LLGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLT 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 318 KLDCLYLQHNDILELP-EFEGNEALNELHASNNFIKIIPKAMcSNLPHLKILDLRDNKITELPDELCLLRNLNRLDVSNN 396
Cdd:COG4886 160 NLKSLDLSNNQLTDLPeELGNLTNLKELDLSNNQITDLPEPL-GNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNN 238

                       250       260
                ....*....|....*....|....*...
gi 45551891 397 TISVLPVtLSSLAHLISLQVEGNPIKTI 424
Cdd:COG4886 239 QLTDLPE-LGNLTNLEELDLSNNQLTDL 265
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 158-598 1.15e-18

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 90.68  E-value: 1.15e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  158 LNNLDLSSNTLT-HISPKIENLQSLTVLTLHDNALV-ELPPEIGKLEKLVRLNVSHNKLS-QLPRAMYSLPELRHLNISY 234
Cdd:PLN00113 166 LKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLVgQIPRELGQMKSLKWIYLGYNNLSgEIPYEIGGLTSLNHLDLVY 245

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  235 NefvelnpdisdlhmlefldgghNNIQSLPGGIGFLVRLTALLLPYNHIK-ELPPDLVNMRSLQKIDLMHNDLT-SLPED 312
Cdd:PLN00113 246 N----------------------NLTGPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSLSgEIPEL 303

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  313 MGLLRKLDCLYLqhndilelpefegnealnelhASNNFIKIIPKAMCSnLPHLKILDLRDNKIT-ELPDELCLLRNLNRL 391
Cdd:PLN00113 304 VIQLQNLEILHL---------------------FSNNFTGKIPVALTS-LPRLQVLQLWSNKFSgEIPKNLGKHNNLTVL 361

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  392 DVSNNTIS-VLPVTLSSLAHLISLQVEGNPIKT-IRRDILQCGTTRILKtLHDRAVAKAKEEGGGVDDASTSAGISVTRL 469
Cdd:PLN00113 362 DLSTNNLTgEIPEGLCSSGNLFKLILFSNSLEGeIPKSLGACRSLRRVR-LQDNSFSGELPSEFTKLPLVYFLDISNNNL 440

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  470 RGgQMDDG--DIP-------------GNFPDRYKLRHTRTLAVNLEELT-SVPDQVFQIARdegVHVVDFARNQLS-TLP 532
Cdd:PLN00113 441 QG-RINSRkwDMPslqmlslarnkffGGLPDSFGSKRLENLDLSRNQFSgAVPRKLGSLSE---LMQLKLSENKLSgEIP 516

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 45551891  533 NGLQHMKDLVTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLN-DLPTEFGVLNTLRELNIANNRF 598
Cdd:PLN00113 517 DELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSgEIPKNLGNVESLVQVNISHNHL 583
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 153-666 4.17e-15

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 79.51  E-value: 4.17e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  153 WNQVPLNN------LDLSSNTLT-HISPKIENLQSLTVLTLHDNALV-ELPPEIGKLEKLVR-LNVSHNKLS-QLPRAmy 222
Cdd:PLN00113  60 WQGITCNNssrvvsIDLSGKNISgKISSAIFRLPYIQTINLSNNQLSgPIPDDIFTTSSSLRyLNLSNNNFTgSIPRG-- 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  223 SLPELRHLNISYNEFV-ELNPDISDLHMLEFLD-GGHNNIQSLPGGIGFLVRLTALLLPYNH-IKELPPDLVNMRSLQKI 299
Cdd:PLN00113 138 SIPNLETLDLSNNMLSgEIPNDIGSFSSLKVLDlGGNVLVGKIPNSLTNLTSLEFLTLASNQlVGQIPRELGQMKSLKWI 217

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  300 DLMHNDLT-SLPEDMGLLRKLDCLYLQHNDIL-ELPEFEGNeaLNELH----ASNNFIKIIPKAMCSnLPHLKILDLRDN 373
Cdd:PLN00113 218 YLGYNNLSgEIPYEIGGLTSLNHLDLVYNNLTgPIPSSLGN--LKNLQylflYQNKLSGPIPPSIFS-LQKLISLDLSDN 294

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  374 KIT-ELPDELCLLRNLNRLDV-SNNTISVLPVTLSSLAHLISLQVEGNpiktirrdilqcgttrilktlhdravakakee 451
Cdd:PLN00113 295 SLSgEIPELVIQLQNLEILHLfSNNFTGKIPVALTSLPRLQVLQLWSN-------------------------------- 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  452 gggvddastsagisvtRLRGGqmddgdIPGNFPDRYKLRhtrtlavnleeltsvpdqvfqiardegvhVVDFARNQLS-T 530
Cdd:PLN00113 343 ----------------KFSGE------IPKNLGKHNNLT-----------------------------VLDLSTNNLTgE 371

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  531 LPNGLQHMKDLVTELVLSNNVIGYVPQFIS---QFTRISFLNLSNNLLndLPTEFGVLNTLRELNIANNRFPC-IPNCVY 606
Cdd:PLN00113 372 IPEGLCSSGNLFKLILFSNSLEGEIPKSLGacrSLRRVRLQDNSFSGE--LPSEFTKLPLVYFLDISNNNLQGrINSRKW 449

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 45551891  607 ELQGLEILIASENHIkMLNVSGLQNMRRLSTLDLRNNDI-ETVPPILGNLTNITHLELVGN 666
Cdd:PLN00113 450 DMPSLQMLSLARNKF-FGGLPDSFGSKRLENLDLSRNQFsGAVPRKLGSLSELMQLKLSEN 509
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
520-669 4.29e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 78.05  E-value: 4.29e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 520 VVDFARNQLSTLPNGLQHMKDLvTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLNDLPTEFGVLNTLRELNIANNRFP 599
Cdd:COG4886 117 SLDLSGNQLTDLPEELANLTNL-KELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQIT 195

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 600 CIPNCVYELQGLEILIASENHIKMLNVSgLQNMRRLSTLDLRNNDIETVPpILGNLTNITHLELVGNPFR 669
Cdd:COG4886 196 DLPEPLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLT 263
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
230-431 5.37e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 77.67  E-value: 5.37e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 230 LNISYNEFVELNPDISDLHMLEFLDGGHNNIQSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNdltsl 309
Cdd:COG4886  32 LLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN----- 106

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 310 pEDMGLLRKLDCLYLQHNDILELP-EFEGNEALNELHASNNFIKIIPKAMcSNLPHLKILDLRDNKITELPDELCLLRNL 388
Cdd:COG4886 107 -EELSNLTNLESLDLSGNQLTDLPeELANLTNLKELDLSNNQLTDLPEPL-GNLTNLKSLDLSNNQLTDLPEELGNLTNL 184

                       170       180       190       200
                ....*....|....*....|....*....|....*....|...
gi 45551891 389 NRLDVSNNTISVLPVTLSSLAHLISLQVEGNPIKTIRRDILQC 431
Cdd:COG4886 185 KELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANL 227
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
532-669 1.09e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 73.43  E-value: 1.09e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 532 PNGLQHMKDLvTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLNDLPTEFGVLNTLRELNIANNRFPCIPNCVYELQGL 611
Cdd:COG4886 106 NEELSNLTNL-ESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNL 184

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 45551891 612 EILIASENHIKMLNVSgLQNMRRLSTLDLRNNDIETVPPILGNLTNITHLELVGNPFR 669
Cdd:COG4886 185 KELDLSNNQITDLPEP-LGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLT 241
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
153-663 1.87e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 73.04  E-value: 1.87e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 153 WNQVPLNNLDLSSNTLTHISPKIENLQSLTVLTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNI 232
Cdd:COG4886  24 LILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDL 103

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 233 SYNEfvelnpDISDLHMLEFLDGGHNNIQSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPED 312
Cdd:COG4886 104 SGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEE 177

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 313 MGLLRKLDCLYLQHNDILELP-EFEGNEALNELHASNNFIKIIPKAMcSNLPHLKILDLRDNKITELPDelcllrnlnrl 391
Cdd:COG4886 178 LGNLTNLKELDLSNNQITDLPePLGNLTNLEELDLSGNQLTDLPEPL-ANLTNLETLDLSNNQLTDLPE----------- 245

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 392 dvsnntisvlpvtLSSLAHLISLqvegnpiktirrdilqcgttrilktlhdravakakeegggvddastsagisvtrlrg 471
Cdd:COG4886 246 -------------LGNLTNLEEL--------------------------------------------------------- 255

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 472 gqmddgdipgnfpdryklrhtrtlavnleeltsvpdqvfqiardegvhvvDFARNQLSTLPNgLQHMKDLvTELVLSNNv 551
Cdd:COG4886 256 --------------------------------------------------DLSNNQLTDLPP-LANLTNL-KTLDLSNN- 282

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 552 igyvpqfisqftrisflnlsnnLLNDLPTEFGVLNTLRELNIANNRFPCIPNCVYELQGLEILIASENHIKMLNVSGLQN 631
Cdd:COG4886 283 ----------------------QLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTL 340

                       490       500       510
                ....*....|....*....|....*....|..
gi 45551891 632 MRRLSTLDLRNNDIETVPPILGNLTNITHLEL 663
Cdd:COG4886 341 ALSLSLLALLTLLLLLNLLSLLLTLLLTLGLL 372
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
158-355 2.74e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 72.27  E-value: 2.74e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 158 LNNLDLSSNTLTHISPKIENLQSLTVLTLHDNALVELPpEIGKLEKLVRLNVSHNKLSQLPrAMYSLPELRHLNISYNEF 237
Cdd:COG4886 207 LEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLP-PLANLTNLKTLDLSNNQL 284

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 238 VELNPD-ISDLHMLEFLDGGHNNIQSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLL 316
Cdd:COG4886 285 TDLKLKeLELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLT 364

                       170       180       190
                ....*....|....*....|....*....|....*....
gi 45551891 317 RKLDCLYLQHNDILELPEFEGNEALNELHASNNFIKIIP 355
Cdd:COG4886 365 LLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLL 403
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 272-426 1.53e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 67.50  E-value: 1.53e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 272 RLTALLLPYNHIKELPpDLVNMRSLQKIDLMHNDLTSLpEDMGLLRKLDCLYLQHNDILELPEFEGNEALNELHASNNFI 351
Cdd:cd21340   3 RITHLYLNDKNITKID-NLSLCKNLKVLYLYDNKITKI-ENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRI 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 352 KII----------------------------PKAMCSNLPHLKILDLRDNKITELpDELCLLRNLNRLDVSNNTIS---V 400
Cdd:cd21340  81 SVVeglenltnleelhienqrlppgekltfdPRSLAALSNSLRVLNISGNNIDSL-EPLAPLRNLEQLDASNNQISdleE 159

                       170       180
                ....*....|....*....|....*.
gi 45551891 401 LPVTLSSLAHLISLQVEGNPIKTIRR 426
Cdd:cd21340 160 LLDLLSSWPSLRELDLTGNPVCKKPK 185
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 115-349 2.89e-12

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 70.26  E-value: 2.89e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  115 SNKALARVPKRLYDINEADADSKAVNleQLTIKEEDAWWNQVPLNNLDLSSNTL-THISPKIENLQSLTVLTLHDNALV- 192
Cdd:PLN00113 341 SNKFSGEIPKNLGKHNNLTVLDLSTN--NLTGEIPEGLCSSGNLFKLILFSNSLeGEIPKSLGACRSLRRVRLQDNSFSg 418

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  193 ELPPEIGKLEKLVRLNVSHNKLS-QLPRAMYSLPELRHLNISYNEFVELNPDISDLHMLEFLDGGHNNIQ-SLPGGIGFL 270
Cdd:PLN00113 419 ELPSEFTKLPLVYFLDISNNNLQgRINSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSgAVPRKLGSL 498

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  271 VRLTALLLPYNHIK-ELPPDLVNMRSLQKIDLMHNDLT-SLP---EDMGLLRKLDclyLQHNDIL-ELPEFEGN-EALNE 343
Cdd:PLN00113 499 SELMQLKLSENKLSgEIPDELSSCKKLVSLDLSHNQLSgQIPasfSEMPVLSQLD---LSQNQLSgEIPKNLGNvESLVQ 575


                 ....*.
gi 45551891  344 LHASNN 349
Cdd:PLN00113 576 VNISHN 581
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
182-405 4.87e-12

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 69.34  E-value: 4.87e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  182 TVLTLHDNALVELPPEIGklEKLVRLNVSHNKLSQLPRAMYSlpELRHLNISYNEFVELNPDISDlhMLEFLDGGHNNIQ 261
Cdd:PRK15370 181 TELRLKILGLTTIPACIP--EQITTLILDNNELKSLPENLQG--NIKTLYANSNQLTSIPATLPD--TIQEMELSINRIT 254

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  262 SLPGGIGflVRLTALLLPYNHIKELPPDLVNmrSLQKIDLMHNDLTSLPEDmgLLRKLDCLYLQHNDILELPEfEGNEAL 341
Cdd:PRK15370 255 ELPERLP--SALQSLDLFHNKISCLPENLPE--ELRYLSVYDNSIRTLPAH--LPSGITHLNVQSNSLTALPE-TLPPGL 327

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 45551891  342 NELHASNNFIKIIPKAMCsnlPHLKILDLRDNKITELPDelCLLRNLNRLDVSNNTISVLPVTL 405
Cdd:PRK15370 328 KTLEAGENALTSLPASLP---PELQVLDVSKNQITVLPE--TLPPTITTLDVSRNALTNLPENL 386
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 155-310 2.40e-11

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 67.18  E-value: 2.40e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  155 QVPLNN-LDLSSNTLT-HISPKIENLQSLTVLTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQ-LPRAMYSLPELRHLN 231
Cdd:PLN00113 426 KLPLVYfLDISNNNLQgRINSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSGaVPRKLGSLSELMQLK 505

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  232 ISYNEFVELNPD-ISDLHMLEFLDGGHNNIQ-SLPGGIGFLVRLTALLLPYNHIK-ELPPDLVNMRSLQKIDLMHNDL-T 307
Cdd:PLN00113 506 LSENKLSGEIPDeLSSCKKLVSLDLSHNQLSgQIPASFSEMPVLSQLDLSQNQLSgEIPKNLGNVESLVQVNISHNHLhG 585


                 ...
gi 45551891  308 SLP 310
Cdd:PLN00113 586 SLP 588
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
304-668 1.67e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 63.80  E-value: 1.67e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 304 NDLTSLPEDMGLLRKLDCLYLQHNDILELPEFEGNEALNELHASNNfikiipkAMCSNLPHLKILDLRDNKITELPDELC 383
Cdd:COG4886  61 LLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPEELA 133

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 384 LLRNLNRLDVSNNTISVLPVTLSSLAHLISLQVEGNPIKTIRRDILQCgttrilktlhdravakakeegggvddastsag 463
Cdd:COG4886 134 NLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNL-------------------------------- 181

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 464 isvtrlrggqmddgdipgnfpdryklrhtrtlaVNLEELtsvpdqvfqiardegvhvvDFARNQLSTLPNGLQHMKDLvT 543
Cdd:COG4886 182 ---------------------------------TNLKEL-------------------DLSNNQITDLPEPLGNLTNL-E 208

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 544 ELVLSNNvigyvpqfisqftrisflnlsnnLLNDLPTEFGVLNTLRELNIANNRFPCIPNcvyelqgleiliasenhikm 623
Cdd:COG4886 209 ELDLSGN-----------------------QLTDLPEPLANLTNLETLDLSNNQLTDLPE-------------------- 245

                       330       340       350       360
                ....*....|....*....|....*....|....*....|....*
gi 45551891 624 lnvsgLQNMRRLSTLDLRNNDIETVPPiLGNLTNITHLELVGNPF 668
Cdd:COG4886 246 -----LGNLTNLEELDLSNNQLTDLPP-LANLTNLKTLDLSNNQL 284
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 158-270 8.88e-09

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 59.09  E-value: 8.88e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  158 LNNLDLSSNTLTHISP-KIENLQSLTVLTLHDNALV-ELPPEIGKLEKLVRLNVSHNKLS-QLPRAMYSLPELRHLNISY 234
Cdd:PLN00113 477 LENLDLSRNQFSGAVPrKLGSLSELMQLKLSENKLSgEIPDELSSCKKLVSLDLSHNQLSgQIPASFSEMPVLSQLDLSQ 556

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 45551891  235 NEFV-ELNPDISDLHMLEFLDGGHNNIQ-SLPGGIGFL 270
Cdd:PLN00113 557 NQLSgEIPKNLGNVESLVQVNISHNHLHgSLPSTGAFL 594
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 168-379 2.80e-08

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 54.79  E-value: 2.80e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 168 LTHIS------PKIENL---QSLTVLTLHDNALVELPPeIGKLEKLVRLNVSHNKLSQLPRaMYSLPELRHLNISYNEFV 238
Cdd:cd21340   4 ITHLYlndkniTKIDNLslcKNLKVLYLYDNKITKIEN-LEFLTNLTHLYLQNNQIEKIEN-LENLVNLKKLYLGGNRIS 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 239 ELNpDISDLHMLEFLdggHNNIQSLPGGIGFLVR---LTALLlpynhikelppdlvnmRSLQKIDLMHNDLTSLpEDMGL 315
Cdd:cd21340  82 VVE-GLENLTNLEEL---HIENQRLPPGEKLTFDprsLAALS----------------NSLRVLNISGNNIDSL-EPLAP 140

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 45551891 316 LRKLDCLYLQHNDILELPEFEGnealnelhasnnfikiipkaMCSNLPHLKILDLRDNKITELP 379
Cdd:cd21340 141 LRNLEQLDASNNQISDLEELLD--------------------LLSSWPSLRELDLTGNPVCKKP 184
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
181-421 1.75e-07

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 54.78  E-value: 1.75e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  181 LTVLTLHDNALVELP---PEIGKLEklvrlnVSHNKLSQLPRAMyslPELRHLNISYNEFVELNPDISDLHMLEFLDGGH 257
Cdd:PRK15387 224 ITTLVIPDNNLTSLPalpPELRTLE------VSGNQLTSLPVLP---PGLLELSIFSNPLTHLPALPSGLCKLWIFGNQL 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  258 NNIQSLPGGI-------GFLVRLTAL------LLPYNHIKELPPDLVNmrSLQKIDLMHNDLTSLPEdmgLLRKLDCLYL 324
Cdd:PRK15387 295 TSLPVLPPGLqelsvsdNQLASLPALpselckLWAYNNQLTSLPTLPS--GLQELSVSDNQLASLPT---LPSELYKLWA 369

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  325 QHNDILELPEFEgnEALNELHASNNFIKIIPKamcsnLP-HLKILDLRDNKITELPdelCLLRNLNRLDVSNNTISVLPV 403
Cdd:PRK15387 370 YNNRLTSLPALP--SGLKELIVSGNRLTSLPV-----LPsELKELMVSGNRLTSLP---MLPSGLLSLSVYRNQLTRLPE 439

                        250
                 ....*....|....*...
gi 45551891  404 TLSSLAHLISLQVEGNPI 421
Cdd:PRK15387 440 SLIHLSSETTVNLEGNPL 457
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 158-310 3.04e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 51.71  E-value: 3.04e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 158 LNNLDLSSNTLTHIsPKIENLQSLTVLTLHDNALVELPPeIGKLEKLVRLNVSHNKLSQL-------------------- 217
Cdd:cd21340  26 LKVLYLYDNKITKI-ENLEFLTNLTHLYLQNNQIEKIEN-LENLVNLKKLYLGGNRISVVeglenltnleelhienqrlp 103

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 218 --------PRAMYSL-PELRHLNISYNEFVELNPdISDLHMLEFLDGGHNNIQSlpggigflvrltalllpynhIKELPP 288
Cdd:cd21340 104 pgekltfdPRSLAALsNSLRVLNISGNNIDSLEP-LAPLRNLEQLDASNNQISD--------------------LEELLD 162

                       170       180
                ....*....|....*....|..
gi 45551891 289 DLVNMRSLQKIDLMHNDLTSLP 310
Cdd:cd21340 163 LLSSWPSLRELDLTGNPVCKKP 184
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 585-672 3.72e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 51.33  E-value: 3.72e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 585 LNTLRELNIANNRFP-----CI-PNCVYELQG-LEILIASENHIKmlNVSGLQNMRRLSTLDLRNN---DIETVPPILGN 654
Cdd:cd21340  89 LTNLEELHIENQRLPpgeklTFdPRSLAALSNsLRVLNISGNNID--SLEPLAPLRNLEQLDASNNqisDLEELLDLLSS 166

                        90
                ....*....|....*....
gi 45551891 655 LTNITHLELVGNPF-RQPR 672
Cdd:cd21340 167 WPSLRELDLTGNPVcKKPK 185
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
272-539 6.63e-07

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 52.78  E-value: 6.63e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  272 RLTALLLPYNHIKELPPDL-VNMRSLQkidLMHNDLTSLPEDmgLLRKLDCLYLQHNDILELPEFegnealnelhasnnf 350
Cdd:PRK15370 200 QITTLILDNNELKSLPENLqGNIKTLY---ANSNQLTSIPAT--LPDTIQEMELSINRITELPER--------------- 259

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  351 ikiIPKAmcsnlphLKILDLRDNKITELPDelCLLRNLNRLDVSNNTISVLPVTLSSlaHLISLQVEGNPIkTIRRDILQ 430
Cdd:PRK15370 260 ---LPSA-------LQSLDLFHNKISCLPE--NLPEELRYLSVYDNSIRTLPAHLPS--GITHLNVQSNSL-TALPETLP 324

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  431 CGttriLKTLhdravaKAKEEGGGVDDASTSAGISVTRLRGGQMDdgDIPGNFPDRYKlrhtrTLAVNLEELTSVPDQVf 510
Cdd:PRK15370 325 PG----LKTL------EAGENALTSLPASLPPELQVLDVSKNQIT--VLPETLPPTIT-----TLDVSRNALTNLPENL- 386

                        250       260
                 ....*....|....*....|....*....
gi 45551891  511 qiarDEGVHVVDFARNQLSTLPNGLQHMK 539
Cdd:PRK15370 387 ----PAALQIMQASRNNLVRLPESLPHFR 411
LRR_8 pfam13855
Leucine rich repeat;
158-214 2.64e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 45.21  E-value: 2.64e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 45551891   158 LNNLDLSSNTLTHISPKI-ENLQSLTVLTLHDNALVELPPE-IGKLEKLVRLNVSHNKL 214
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
317-375 5.10e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 44.44  E-value: 5.10e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 45551891   317 RKLDCLYLQHNDILELPE--FEGNEALNELHASNNFIKIIPKAMCSNLPHLKILDLRDNKI 375
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
203-260 1.28e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 43.28  E-value: 1.28e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891   203 KLVRLNVSHNKLSQL-PRAMYSLPELRHLNISYNEFVELNPD-ISDLHMLEFLDGGHNNI 260
Cdd:pfam13855   2 NLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
158-524 4.72e-05

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 46.69  E-value: 4.72e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  158 LNNLDLSSNTLTHISPKIENLQSLTVLTLHDNALVELPPeigkleKLVRLNVSHNKLSQLPramySLP-ELRHLNISYNE 236
Cdd:PRK15387 264 LLELSIFSNPLTHLPALPSGLCKLWIFGNQLTSLPVLPP------GLQELSVSDNQLASLP----ALPsELCKLWAYNNQ 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  237 FVELNPDISDLHMLEFLDgghNNIQSLPggigflvrltalllpynhikELPPDLVnmrslqKIDLMHNDLTSLPedmGLL 316
Cdd:PRK15387 334 LTSLPTLPSGLQELSVSD---NQLASLP--------------------TLPSELY------KLWAYNNRLTSLP---ALP 381

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  317 RKLDCLYLQHNDILELPEFEGNeaLNELHASNNFIKIIPKamcsnLPH-LKILDLRDNKITELPDELCLLRNLNRLDVSN 395
Cdd:PRK15387 382 SGLKELIVSGNRLTSLPVLPSE--LKELMVSGNRLTSLPM-----LPSgLLSLSVYRNQLTRLPESLIHLSSETTVNLEG 454

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  396 NTISvlPVTLSSLAHLISLQVEGNPIktIRRDILQCGTTRILKTLH----DRAVAKAKEEGGGVDDASTSagisvtrlrg 471
Cdd:PRK15387 455 NPLS--ERTLQALREITSAPGYSGPI--IRFDMAGASAPRETRALHlaaaDWLVPAREGEPAPADRWHMF---------- 520

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 45551891  472 GQMDDGDIPGNFPDRykLRHTRTLAVNLEELTSVPDQVFQIARDEGVHVVDFA 524
Cdd:PRK15387 521 GQEDNADAFSLFLDR--LSETENFIKDAGFKAQISSWLAQLAEDEALRANTFA 571
LRR_8 pfam13855
Leucine rich repeat;
272-329 8.46e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.97  E-value: 8.46e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891   272 RLTALLLPYNHIKELPPD-LVNMRSLQKIDLMHNDLTSL-PEDMGLLRKLDCLYLQHNDI 329
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGaFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
526-670 1.53e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 44.54  E-value: 1.53e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 526 NQLSTLPNGLQHMKDLVTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLNDLPTEFGVLNTLRELNIANNRFPCIPNCV 605
Cdd:COG4886  13 LLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDL 92

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 45551891 606 YELQGLEILIASENhikmlnvSGLQNMRRLSTLDLRNNDIETVPPILGNLTNITHLELVGNPFRQ 670
Cdd:COG4886  93 GDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTD 150
LRR_8 pfam13855
Leucine rich repeat;
609-668 2.05e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.82  E-value: 2.05e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 45551891   609 QGLEILIASENHIKMLNVSGLQNMRRLSTLDLRNNDIETVPPI-LGNLTNITHLELVGNPF 668
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 158-225 2.88e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 44.04  E-value: 2.88e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 45551891  158 LNNLDLSSNTLT-HISPKIENLQSLTVLTLHDNALVELPPE-IGKLEKLVRLNVSHNKLS-QLPRAMYSLP 225
Cdd:PLN03150 444 LQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNGSIPEsLGQLTSLRILNLNGNSLSgRVPAALGGRL 514
LRR_8 pfam13855
Leucine rich repeat;
225-283 5.93e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 38.27  E-value: 5.93e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 45551891   225 PELRHLNISYNEFVELNPDI-SDLHMLEFLDGGHNNIQSL-PGGIGFLVRLTALLLPYNHI 283
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 252-327 6.62e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 42.88  E-value: 6.62e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  252 FLDGGHNNIQSL----PGGIGFLVRLTALLLPYNHIK-ELPPDLVNMRSLQKIDLMHNDLT-SLPEDMGLLRKLDCLYLQ 325
Cdd:PLN03150 419 FIDGLGLDNQGLrgfiPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLN 498


                 ..
gi 45551891  326 HN 327
Cdd:PLN03150 499 GN 500
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 202-345 8.79e-04

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 42.55  E-value: 8.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891   202 EKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEFVELNPDISDLHMLEFLD-GGHNNIQSLPGGIGFLVRLTALLLPY 280
Cdd:PLN03210  611 ENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSKNLKEIPDLSMATNLETLKlSDCSSLVELPSSIQYLNKLEDLDMSR 690

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 45551891   281 NHIKELPPDLVNMRSLQKIDLMH-NDLTSLPEdmgLLRKLDCLYLQHNDILELPEFEGNEALNELH 345
Cdd:PLN03210  691 CENLEILPTGINLKSLYRLNLSGcSRLKSFPD---ISTNISWLDLDETAIEEFPSNLRLENLDELI 753
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
493-693 1.01e-03

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 42.38  E-value: 1.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  493 RTLAVNLEELTSVPDQVfqiarDEGVHVVDFARNQLSTLPnglQHMKDLVTELVLSNNVIGYVPQfisqftrisflnlsn 572
Cdd:PRK15370 265 QSLDLFHNKISCLPENL-----PEELRYLSVYDNSIRTLP---AHLPSGITHLNVQSNSLTALPE--------------- 321

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891  573 nllndlptefgvlntlrelniannrfpCIPncvyelQGLEILIASENHIKMLNVS---GLQNmrrlstLDLRNNDI---- 645
Cdd:PRK15370 322 ---------------------------TLP------PGLKTLEAGENALTSLPASlppELQV------LDVSKNQItvlp 362

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 45551891  646 ETVPPILGNLtNITHLELVGNPFRQPRHQILMKGTDAIMSYLRDRIPT 693
Cdd:PRK15370 363 ETLPPTITTL-DVSRNALTNLPENLPAALQIMQASRNNLVRLPESLPH 409
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
158-317 2.81e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 40.69  E-value: 2.81e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 158 LNNLDLSSNTLTHIsPKIENLQSLTVLTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEF 237
Cdd:COG4886 252 LEELDLSNNQLTDL-PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLL 330

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 238 VELNPDISDLHMLEFLDGGHNNIQSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLLR 317
Cdd:COG4886 331 KGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDA 410
LRR_8 pfam13855
Leucine rich repeat;
363-421 3.52e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 36.35  E-value: 3.52e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 45551891   363 PHLKILDLRDNKITELPDELCLLRNLNRL-DVSNNTISVL-PVTLSSLAHLISLQVEGNPI 421
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVlDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 111-362 6.17e-03

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 39.86  E-value: 6.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891   111 TLNLSNKALARVPKRLYDINeadadskAVNLEQLTIKEEDAWWNQVPLNNLdlssntLTHISPkienlqSLTVLTLHDN- 189
Cdd:PLN03210  729 WLDLDETAIEEFPSNLRLEN-------LDELILCEMKSEKLWERVQPLTPL------MTMLSP------SLTRLFLSDIp 789

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891   190 ALVELPPEIGKLEKLVRLNVSHNK-LSQLPRAMySLPELRHLNISYNEFVELNPDISdlhmlefldgghNNIQSlpggig 268
Cdd:PLN03210  790 SLVELPSSIQNLHKLEHLEIENCInLETLPTGI-NLESLESLDLSGCSRLRTFPDIS------------TNISD------ 850

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891   269 flvrltaLLLPYNHIKELPPDLVNMRSLQKIDLMH-NDLTSLPEDMGLLRKLDclYLQHNDILELPEFEGNEALNEL-HA 346
Cdd:PLN03210  851 -------LNLSRTGIEEVPWWIEKFSNLSFLDMNGcNNLQRVSLNISKLKHLE--TVDFSDCGALTEASWNGSPSEVaMA 921

                         250
                  ....*....|....*.
gi 45551891   347 SNNFIKIIPKAMCSNL 362
Cdd:PLN03210  922 TDNIHSKLPSTVCINF 937
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 155-377 6.28e-03

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 39.26  E-value: 6.28e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 155 QVPLNNLDLSSNTLTHISPKIENLQSLTV--LTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPE------ 226
Cdd:cd00116   2 QLSLKGELLKTERATELLPKLLCLQVLRLegNTLGEEAAKALASALRPQPSLKELCLSLNETGRIPRGLQSLLQgltkgc 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 45551891 227 -LRHLNISYNEFVELNPD-ISDLHMLEFLDGGHNNIQSLPGGIGFLVrLTALllpynhiKELPPDLvnmrslQKIDLMHN 304
Cdd:cd00116  82 gLQELDLSDNALGPDGCGvLESLLRSSSLQELKLNNNGLGDRGLRLL-AKGL-------KDLPPAL------EKLVLGRN 147

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 45551891 305 DLTS-----LPEDMGLLRKLDCLYLQHNDILElpefEGNEALNELHASNnfikiipkamcsnlPHLKILDLRDNKITE 377
Cdd:cd00116 148 RLEGasceaLAKALRANRDLKELNLANNGIGD----AGIRALAEGLKAN--------------CNLEVLDLNNNGLTD 207
LRR_8 pfam13855
Leucine rich repeat;
250-306 9.25e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.19  E-value: 9.25e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 45551891   250 LEFLDGGHNNIQSLPGGIGF-LVRLTALLLPYNHIKELPPD-LVNMRSLQKIDLMHNDL 306
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAFKgLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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