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Conserved domains on  [gi|24645942|ref|NP_731573|]
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sarcomere length short, isoform B [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Filament super family cl25641
Intermediate filament protein;
542-673 3.03e-05

Intermediate filament protein;


The actual alignment was detected with superfamily member pfam00038:

Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 47.22  E-value: 3.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942   542 DIDKIRDDLQSTKQMLALELRNREAQDRE-------------NK-KLLAKIRTLETELE------REKSREKNLEYGSNV 601
Cdd:pfam00038  76 ELDNLRLAAEDFRQKYEDELNLRTSAENDlvglrkdldeatlARvDLEAKIESLKEELAflkknhEEEVRELQAQVSDTQ 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942   602 IVATMDPTPTAEQTYV-NSLKREVED-ARKVSKEVEQNYQSTAEQLVE-----------AKTEIEEQRRQIQLLE----- 663
Cdd:pfam00038 156 VNVEMDAARKLDLTSAlAEIRAQYEEiAAKNREEAEEWYQSKLEELQQaaarngdalrsAKEEITELRRTIQSLEielqs 235

                         170
                  ....*....|.
gi 24645942   664 -RKLAAALQAT 673
Cdd:pfam00038 236 lKKQKASLERQ 246
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 541-806 6.17e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.89  E-value: 6.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942    541 DDIDKIRDDLQSTKQMLA-LELRNREAQDREnKKLLAKIRTLETELEREKSREKNLEYGSNvivatmdptptAEQTYVNS 619
Cdd:TIGR02168  281 EEIEELQKELYALANEISrLEQQKQILRERL-ANLERQLEELEAQLEELESKLDELAEELA-----------ELEEKLEE 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942    620 LKREVEDARKVSKEVEQNYQSTAEQLVEAKTEIEEQRRQIQLLERKLaAALQATPSTNRPHISncfayddddyddcfHYD 699
Cdd:TIGR02168  349 LKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI-ASLNNEIERLEARLE--------------RLE 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942    700 HYHAARHQGGGSLDGSRRPSDANFGRDSSPELEPEVSESdpdEPEEKKVERRERRSGKELKILRSKLTKLKVKEEAAKKE 779
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKELQAELEELEEELEEL---QEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490

                          250       260
                   ....*....|....*....|....*..
gi 24645942    780 KDALKQAMKKNQSILKEENKKFKKLEK 806
Cdd:TIGR02168  491 LDSLERLQENLEGFSEGVKALLKNQSG 517
WH2 super family cl41728
Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins; This ...
 449-475 6.03e-03

Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins; This family contains the Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 (WH2) as well as thymosin-beta (Tbeta; also called beta-thymosin or betaT) domains that are small, widespread intrinsically disordered actin-binding peptides displaying significant sequence variability and different regulations of actin self-assembly in motile and morphogenetic processes. These WH2/betaT peptides are identified by a central consensus actin-binding motif LKKT/V flanked by variable N-terminal and C-terminal extensions; the betaT shares a more extended and conserved C-terminal half than WH2. These single or repeated domains are found in actin-binding proteins (ABPs) such as the hematopoietic-specific protein WASP, its ubiquitously expressed ortholog neural-WASP (N-WASP), WASP-interacting protein (WAS/WASL-interacting protein family members 1 and 2), and WASP-family verprolin homologous protein (WAVE/SCAR) isoforms: WAVE1, WAVE2, and WAVE3. Also included are the WH2 domains found in inverted formin FH2 domain-containing protein (INF2), Cordon bleu (Cobl) protein, vasodilator-stimulated phosphoprotein (VASP) homology protein and actobindin (found in amoebae). These ABPs are commonly multidomain proteins that contain signaling domains and structurally conserved actin-binding motifs, the most important being the WH2 domain motif through which they bind actin in order to direct the location, rate, and timing for actin assembly in the cell into different structures, such as filopodia, lamellipodia, stress fibers, and focal adhesions. The WH2 domain motif is one of the most abundant actin-binding motifs in Wiskott-Aldrich syndrome proteins (WASPs) where they activate Arp2/3-dependent actin nucleation and branching in response to signals mediated by Rho-family GTPases. The thymosin beta (Tbeta) domains in metazoans act in cells as major actin-sequestering peptides; their complex with monomeric ATP-actin (G-ATP-actin) cannot polymerize at either filament (F-actin) end.


The actual alignment was detected with superfamily member cd22076:

Pssm-ID: 425359 [Multi-domain]  Cd Length: 32  Bit Score: 35.33  E-value: 6.03e-03
                        10        20
                ....*....|....*....|....*..
gi 24645942 449 NKLLKQIQGGIKLKPTKTNDRSKPVLD 475
Cdd:cd22076   6 NALLSDINKGKKLKKTVTNDRSAPILD 32
 
Name Accession Description Interval E-value
Filament pfam00038
Intermediate filament protein;
542-673 3.03e-05

Intermediate filament protein;


Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 47.22  E-value: 3.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942   542 DIDKIRDDLQSTKQMLALELRNREAQDRE-------------NK-KLLAKIRTLETELE------REKSREKNLEYGSNV 601
Cdd:pfam00038  76 ELDNLRLAAEDFRQKYEDELNLRTSAENDlvglrkdldeatlARvDLEAKIESLKEELAflkknhEEEVRELQAQVSDTQ 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942   602 IVATMDPTPTAEQTYV-NSLKREVED-ARKVSKEVEQNYQSTAEQLVE-----------AKTEIEEQRRQIQLLE----- 663
Cdd:pfam00038 156 VNVEMDAARKLDLTSAlAEIRAQYEEiAAKNREEAEEWYQSKLEELQQaaarngdalrsAKEEITELRRTIQSLEielqs 235

                         170
                  ....*....|.
gi 24645942   664 -RKLAAALQAT 673
Cdd:pfam00038 236 lKKQKASLERQ 246
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 541-806 6.17e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.89  E-value: 6.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942    541 DDIDKIRDDLQSTKQMLA-LELRNREAQDREnKKLLAKIRTLETELEREKSREKNLEYGSNvivatmdptptAEQTYVNS 619
Cdd:TIGR02168  281 EEIEELQKELYALANEISrLEQQKQILRERL-ANLERQLEELEAQLEELESKLDELAEELA-----------ELEEKLEE 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942    620 LKREVEDARKVSKEVEQNYQSTAEQLVEAKTEIEEQRRQIQLLERKLaAALQATPSTNRPHISncfayddddyddcfHYD 699
Cdd:TIGR02168  349 LKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI-ASLNNEIERLEARLE--------------RLE 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942    700 HYHAARHQGGGSLDGSRRPSDANFGRDSSPELEPEVSESdpdEPEEKKVERRERRSGKELKILRSKLTKLKVKEEAAKKE 779
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKELQAELEELEEELEEL---QEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490

                          250       260
                   ....*....|....*....|....*..
gi 24645942    780 KDALKQAMKKNQSILKEENKKFKKLEK 806
Cdd:TIGR02168  491 LDSLERLQENLEGFSEGVKALLKNQSG 517
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
538-669 7.07e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 7.07e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942 538 DELDDIDKIRDDLQSTKQMLALElRNREAQDRENKKLLAKIRTLETELEREKSREKNLEYGSNVIVATMDPTPTAEQTYV 617
Cdd:COG4717 116 EELEKLEKLLQLLPLYQELEALE-AELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEEL 194

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 24645942 618 NSLKREVEDARKVSKEVEqnyqstaEQLVEAKTEIEEQRRQIQLLERKLAAA 669
Cdd:COG4717 195 QDLAEELEELQQRLAELE-------EELEEAQEELEELEEELEQLENELEAA 239
WH2_WAS_WASL-1 cd22076
Wiskott Aldrich syndrome homology region 2 (WH2 motif) in WAS/WASL-interacting protein family ...
 449-475 6.03e-03

Wiskott Aldrich syndrome homology region 2 (WH2 motif) in WAS/WASL-interacting protein family member 1; This family contains the Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 (WH2) in WAS/WASL-interacting protein family (WIPF, also known as WASP-interacting protein or WIP) member 1 (WIPF1). WIPF1 is a ubiquitously expressed proline-rich multidomain protein and is a binding partner and chaperone of WASP. It stabilizes actin filaments and regulates actin organization and polymerization which are associated with cell migration and invasion. Mutations in the WIPF1 binding site of WASP or in WIPF1 itself cause Wiskott-Aldrich syndrome (WAS), a rare X-linked recessive disease characterized by eczema, thrombocytopenia, immune deficiency, and bloody diarrhea. Aberrant expression of WIPF1 contributes to the invasion and metastasis of several malignancies such breast cancer, glioma and colorectal cancer; it has been identified as an oncoprotein in human pancreatic ductal adenocarcinoma (PDAC) and is associated with poor survival.


Pssm-ID: 409219 [Multi-domain]  Cd Length: 32  Bit Score: 35.33  E-value: 6.03e-03
                        10        20
                ....*....|....*....|....*..
gi 24645942 449 NKLLKQIQGGIKLKPTKTNDRSKPVLD 475
Cdd:cd22076   6 NALLSDINKGKKLKKTVTNDRSAPILD 32
 
Name Accession Description Interval E-value
Filament pfam00038
Intermediate filament protein;
542-673 3.03e-05

Intermediate filament protein;


Pssm-ID: 459643 [Multi-domain]  Cd Length: 313  Bit Score: 47.22  E-value: 3.03e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942   542 DIDKIRDDLQSTKQMLALELRNREAQDRE-------------NK-KLLAKIRTLETELE------REKSREKNLEYGSNV 601
Cdd:pfam00038  76 ELDNLRLAAEDFRQKYEDELNLRTSAENDlvglrkdldeatlARvDLEAKIESLKEELAflkknhEEEVRELQAQVSDTQ 155

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942   602 IVATMDPTPTAEQTYV-NSLKREVED-ARKVSKEVEQNYQSTAEQLVE-----------AKTEIEEQRRQIQLLE----- 663
Cdd:pfam00038 156 VNVEMDAARKLDLTSAlAEIRAQYEEiAAKNREEAEEWYQSKLEELQQaaarngdalrsAKEEITELRRTIQSLEielqs 235

                         170
                  ....*....|.
gi 24645942   664 -RKLAAALQAT 673
Cdd:pfam00038 236 lKKQKASLERQ 246
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 541-806 6.17e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.89  E-value: 6.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942    541 DDIDKIRDDLQSTKQMLA-LELRNREAQDREnKKLLAKIRTLETELEREKSREKNLEYGSNvivatmdptptAEQTYVNS 619
Cdd:TIGR02168  281 EEIEELQKELYALANEISrLEQQKQILRERL-ANLERQLEELEAQLEELESKLDELAEELA-----------ELEEKLEE 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942    620 LKREVEDARKVSKEVEQNYQSTAEQLVEAKTEIEEQRRQIQLLERKLaAALQATPSTNRPHISncfayddddyddcfHYD 699
Cdd:TIGR02168  349 LKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQI-ASLNNEIERLEARLE--------------RLE 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942    700 HYHAARHQGGGSLDGSRRPSDANFGRDSSPELEPEVSESdpdEPEEKKVERRERRSGKELKILRSKLTKLKVKEEAAKKE 779
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKELQAELEELEEELEEL---QEELERLEEALEELREELEEAEQALDAAERELAQLQAR 490

                          250       260
                   ....*....|....*....|....*..
gi 24645942    780 KDALKQAMKKNQSILKEENKKFKKLEK 806
Cdd:TIGR02168  491 LDSLERLQENLEGFSEGVKALLKNQSG 517
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
538-669 7.07e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 7.07e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942 538 DELDDIDKIRDDLQSTKQMLALElRNREAQDRENKKLLAKIRTLETELEREKSREKNLEYGSNVIVATMDPTPTAEQTYV 617
Cdd:COG4717 116 EELEKLEKLLQLLPLYQELEALE-AELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEEL 194

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 24645942 618 NSLKREVEDARKVSKEVEqnyqstaEQLVEAKTEIEEQRRQIQLLERKLAAA 669
Cdd:COG4717 195 QDLAEELEELQQRLAELE-------EELEEAQEELEELEEELEQLENELEAA 239
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 551-672 3.31e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.46  E-value: 3.31e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942 551 QSTKQMLALELRnREAQDRENKKLLAKIRTLETELEREKSREKNLEYGSNVIVATMDptptaeqtyvnSLKREVEDARKV 630
Cdd:COG1196 208 QAEKAERYRELK-EELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELA-----------ELEAELEELRLE 275

                        90       100       110       120
                ....*....|....*....|....*....|....*....|..
gi 24645942 631 SKEVEQNYQSTAEQLVEAKTEIEEQRRQIQLLERKLAAALQA 672
Cdd:COG1196 276 LEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 549-677 3.46e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 3.46e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942 549 DLQSTKQMLALELRNREAQDRENKKLLAKIRTLETELEREKSREKNLEygsnvivatmdptpTAEQTYVNSLKREVEDAR 628
Cdd:COG4942 133 DAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL--------------AELEEERAALEALKAERQ 198

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*....
gi 24645942 629 KVSKEVEQNYQSTAEQLVEAKTEIEEQRRQIQLLERKLAAALQATPSTN 677
Cdd:COG4942 199 KLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 547-672 5.42e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 40.69  E-value: 5.42e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942 547 RDDLQSTKQMLALELrnrEAQDRENKKLLAKIRTLETELE--REKSREKNLEYgsnvivatmdptpTAEQTYVNSLKREV 624
Cdd:COG1196 234 LRELEAELEELEAEL---EELEAELEELEAELAELEAELEelRLELEELELEL-------------EEAQAEEYELLAEL 297

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 24645942 625 EDARKVSKEVEQNYQSTAEQLVEAKTEIEEQRRQIQLLERKLAAALQA 672
Cdd:COG1196 298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEE 345
WH2_WAS_WASL-1 cd22076
Wiskott Aldrich syndrome homology region 2 (WH2 motif) in WAS/WASL-interacting protein family ...
 449-475 6.03e-03

Wiskott Aldrich syndrome homology region 2 (WH2 motif) in WAS/WASL-interacting protein family member 1; This family contains the Wiskott-Aldrich syndrome protein (WASP)-homology domain 2 (WH2) in WAS/WASL-interacting protein family (WIPF, also known as WASP-interacting protein or WIP) member 1 (WIPF1). WIPF1 is a ubiquitously expressed proline-rich multidomain protein and is a binding partner and chaperone of WASP. It stabilizes actin filaments and regulates actin organization and polymerization which are associated with cell migration and invasion. Mutations in the WIPF1 binding site of WASP or in WIPF1 itself cause Wiskott-Aldrich syndrome (WAS), a rare X-linked recessive disease characterized by eczema, thrombocytopenia, immune deficiency, and bloody diarrhea. Aberrant expression of WIPF1 contributes to the invasion and metastasis of several malignancies such breast cancer, glioma and colorectal cancer; it has been identified as an oncoprotein in human pancreatic ductal adenocarcinoma (PDAC) and is associated with poor survival.


Pssm-ID: 409219 [Multi-domain]  Cd Length: 32  Bit Score: 35.33  E-value: 6.03e-03
                        10        20
                ....*....|....*....|....*..
gi 24645942 449 NKLLKQIQGGIKLKPTKTNDRSKPVLD 475
Cdd:cd22076   6 NALLSDINKGKKLKKTVTNDRSAPILD 32
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
466-681 6.46e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 40.39  E-value: 6.46e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942 466 TNDRSKPVLDGLRKFRRQMT-IEEQLQKSQSKINMLSEAPsshALGPGSATALGAGGSRPSIVSAMS-----IDEES--- 536
Cdd:COG3206 210 LSEEAKLLLQQLSELESQLAeARAELAEAEARLAALRAQL---GSGPDALPELLQSPVIQQLRAQLAeleaeLAELSary 286

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942 537 PDELDDIDKIRDDLQSTKQMLALELRNREAQ-DRENKKLLAKIRTLETELEREKSREKNLeygsnvivatmdptPTAEQT 615
Cdd:COG3206 287 TPNHPDVIALRAQIAALRAQLQQEAQRILASlEAELEALQAREASLQAQLAQLEARLAEL--------------PELEAE 352

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24645942 616 YvNSLKREVEDARkvskeveQNYQSTAEQLVEAKTEIEEQRRQIQLLERklaAALQATPS-TNRPHI 681
Cdd:COG3206 353 L-RRLEREVEVAR-------ELYESLLQRLEEARLAEALTVGNVRVIDP---AVVPLKPVsPKKLLI 408
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
557-682 7.85e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.14  E-value: 7.85e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942 557 LALELRNREAQDRENKKLLAKIRTLETELEREKSREKNLEYGSNVIVATMDPTPTAEQtyVNSLKREVEDARKVSKEVEQ 636
Cdd:COG4717  76 LEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQE--LEALEAELAELPERLEELEE 153

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 24645942 637 NYQstaeQLVEAKTEIEEQRRQIQLLERKLAAALQATPSTNRPHIS 682
Cdd:COG4717 154 RLE----ELRELEEELEELEAELAELQEELEELLEQLSLATEEELQ 195
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
543-672 9.81e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 39.61  E-value: 9.81e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24645942 543 IDKIRDDLQSTKQMLAlELRNRE---AQDRENKKLLAKIRTLETELEREKSREKNLEYGSNVIVATMDPTPTA-----EQ 614
Cdd:COG3206 184 LPELRKELEEAEAALE-EFRQKNglvDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDAlpellQS 262

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 24645942 615 TYVNSLKREVEDARKVSKEVEQNYQSTAEQLVEAKTEIEEQRRQIQLLERKLAAALQA 672
Cdd:COG3206 263 PVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEA 320
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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