|
Name |
Accession |
Description |
Interval |
E-value |
| pdxH |
TIGR00558 |
pyridoxamine-phosphate oxidase; This model is similar to Pyridox_oxidase from Pfam but is ... |
33-237 |
1.51e-96 |
|
pyridoxamine-phosphate oxidase; This model is similar to Pyridox_oxidase from Pfam but is designed to find only true pyridoxamine-phosphate oxidase and to ignore the related protein PhzG involved in phenazine biosynthesis. This protein from E. coli was characterized as a homodimer with two FMN per dimer. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine]
Pssm-ID: 273138 Cd Length: 190 Bit Score: 279.77 E-value: 1.51e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 33 NPFCVFRDWLELALKTpEILEPNAAALATVSAEGRPSNRYVLVKEATAEGFTFFTNYGSRKAEDIKSNPYVAISFYWLPL 112
Cdd:TIGR00558 1 DPIEQFERWFEEAIEA-ELPEPNAMTLATVDADGRPSARIVLLKGFDERGFVFYTNYESRKGQELAANPKAALLFPWHSL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 113 RRSVRIEGVAEKISVEDSLKYFHQRPRASQIGAAASPQSQRIPSRSYLDDVEAAIKLELgPDGEVPLP-NWGGYLVRPDL 191
Cdd:TIGR00558 80 ERQVRIEGRVEKVSREESDAYFASRPRGSQIGAWASQQSRPIASREELEARFAELKARF-PDGEVPRPeFWGGYRVVPDE 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 24644901 192 IEFWQGQTDRLHDRIRFRRgggvesevdsklvhKGEDGWVYERLAP 237
Cdd:TIGR00558 159 IEFWQGRPSRLHDRFRYRR--------------DGDGSWRIERLAP 190
|
|
| PdxH |
COG0259 |
Pyridoxine/pyridoxamine 5'-phosphate oxidase [Coenzyme transport and metabolism]; Pyridoxine ... |
10-237 |
1.22e-95 |
|
Pyridoxine/pyridoxamine 5'-phosphate oxidase [Coenzyme transport and metabolism]; Pyridoxine/pyridoxamine 5'-phosphate oxidase is part of the Pathway/BioSystem: Pyridoxal phosphate biosynthesis
Pssm-ID: 440029 Cd Length: 212 Bit Score: 278.61 E-value: 1.22e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 10 LSALRLKYceRKDAFLEDNIKvKNPFCVFRDWLELALKTpEILEPNAAALATVSAEGRPSNRYVLVKEATAEGFTFFTNY 89
Cdd:COG0259 4 LADLRREY--TKGGLDESDLP-ADPLALFARWLEEAEAA-GVPEPNAMTLATVDADGRPSARTVLLKGVDERGFVFYTNY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 90 GSRKAEDIKSNPYVAISFYWLPLRRSVRIEGVAEKISVEDSLKYFHQRPRASQIGAAASPQSQRIPSRSYLDDVEAAIKL 169
Cdd:COG0259 80 ESRKGRELAANPRAALTFFWPELERQVRIEGRVEKVSAAESDAYFASRPRGSQLGAWASPQSQPIASREELEARFAELEA 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24644901 170 ELgPDGEVPLP-NWGGYLVRPDLIEFWQGQTDRLHDRIRFRRGGGvesevdsklvhkgedGWVYERLAP 237
Cdd:COG0259 160 RF-AGGDVPRPpHWGGYRVVPDRIEFWQGRPSRLHDRLRYTREDG---------------GWTIERLAP 212
|
|
| PRK05679 |
PRK05679 |
pyridoxal 5'-phosphate synthase; |
33-237 |
5.50e-87 |
|
pyridoxal 5'-phosphate synthase;
Pssm-ID: 235555 Cd Length: 195 Bit Score: 255.92 E-value: 5.50e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 33 NPFCVFRDWLELALKTpEILEPNAAALATVSAEGRPSNRYVLVKEATAEGFTFFTNYGSRKAEDIKSNPYVAISFYWLPL 112
Cdd:PRK05679 7 EPLALFERWLAEAVKA-ELNDPNAMTLATVDEDGRPSQRIVLLKGFDERGFVFYTNYESRKGRQLAANPKAALLFPWKSL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 113 RRSVRIEGVAEKISVEDSLKYFHQRPRASQIGAAASPQSQRIPSRSYLDDVEAAIKLELGpDGEVPLP-NWGGYLVRPDL 191
Cdd:PRK05679 86 ERQVRVEGRVEKVSAEESDAYFASRPRGSQIGAWASKQSRPISSRAALEAKFAEVKAKFA-QGEVPRPpHWGGYRVVPES 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 24644901 192 IEFWQGQTDRLHDRIRFRRGGGvesevdsklvhkgedGWVYERLAP 237
Cdd:PRK05679 165 IEFWQGRPSRLHDRILYRRDDG---------------GWKIERLAP 195
|
|
| phena_PhzG |
NF038138 |
phenazine biosynthesis FMN-dependent oxidase PhzG; |
33-237 |
1.27e-46 |
|
phenazine biosynthesis FMN-dependent oxidase PhzG;
Pssm-ID: 468380 Cd Length: 205 Bit Score: 153.67 E-value: 1.27e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 33 NPFCVFRDWLELAlKTPEILEPNAAALATVSAEGRPSNRYVLVKEATAEGFTFFTNYGSRKAEDIKSNPYVAISFYWLPL 112
Cdd:NF038138 19 EPLGLLRRWLEAA-VALGVREPRALALATADADGRPSTRIVVVKEVSDRGLVFTTHAGSRKGRELAANPWASGVLYWRET 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 113 RRSVRIEGVAEKISVEDSLKYFHQRPRASQIGAAASPQSQRipsrsyLDDVEA--AIKLELGPDGEvPLP---NWGGYLV 187
Cdd:NF038138 98 SQQISLSGPVERLPDAESDALWAARPVATHAMTAASRQSEP------LDDEAAlrAEARELAEAGG-PLPrpaRFVGYRL 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 24644901 188 RPDLIEFWQGQTDRLHDRIRFRRGGgvesevdsklvhkgeDGWVYERLAP 237
Cdd:NF038138 171 VPEEVEFWAAGPDRLHRRLRYDRDG---------------DGWTHVRLQP 205
|
|
| Putative_PNPOx |
pfam01243 |
Pyridoxamine 5'-phosphate oxidase; Family of domains with putative PNPOx function. Family ... |
50-126 |
4.57e-24 |
|
Pyridoxamine 5'-phosphate oxidase; Family of domains with putative PNPOx function. Family members were predicted to encode pyridoxamine 5'-phosphate oxidase, based on sequence similarity. However, there is no experimental data to validate the predicted activity and purified proteins, such as Swiss:Q06199 and its paralogs, do not possess this activity, nor do they bind to flavin mononucleotide (FMN). To date, the only time functional oxidase activity has been experimentally demonstrated is when the sequences contain both pfam01243 and pfam10590. Moreover, some of the family members that contain both domains have been shown to be involved in phenazine biosynthesis. While some molecular function has been experimentally validated for the proteins containing both domains, the role performed by each domain on its own is unknown.
Pssm-ID: 426149 [Multi-domain] Cd Length: 88 Bit Score: 91.54 E-value: 4.57e-24
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24644901 50 EILEPNAAALATVSAEGRPSNRYVLVKEATAE-GFTFFTNYGSRKAEDIKSNPYVAISFYWLPLRRSVRIEGVAEKIS 126
Cdd:pfam01243 8 FLAEPNAVVLATVDKDGRPNVRPVGLKYGFDTvGILFATNTDSRKARNLEENPRVALLFGDPELRRGVRIEGTAEIVT 85
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| pdxH |
TIGR00558 |
pyridoxamine-phosphate oxidase; This model is similar to Pyridox_oxidase from Pfam but is ... |
33-237 |
1.51e-96 |
|
pyridoxamine-phosphate oxidase; This model is similar to Pyridox_oxidase from Pfam but is designed to find only true pyridoxamine-phosphate oxidase and to ignore the related protein PhzG involved in phenazine biosynthesis. This protein from E. coli was characterized as a homodimer with two FMN per dimer. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine]
Pssm-ID: 273138 Cd Length: 190 Bit Score: 279.77 E-value: 1.51e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 33 NPFCVFRDWLELALKTpEILEPNAAALATVSAEGRPSNRYVLVKEATAEGFTFFTNYGSRKAEDIKSNPYVAISFYWLPL 112
Cdd:TIGR00558 1 DPIEQFERWFEEAIEA-ELPEPNAMTLATVDADGRPSARIVLLKGFDERGFVFYTNYESRKGQELAANPKAALLFPWHSL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 113 RRSVRIEGVAEKISVEDSLKYFHQRPRASQIGAAASPQSQRIPSRSYLDDVEAAIKLELgPDGEVPLP-NWGGYLVRPDL 191
Cdd:TIGR00558 80 ERQVRIEGRVEKVSREESDAYFASRPRGSQIGAWASQQSRPIASREELEARFAELKARF-PDGEVPRPeFWGGYRVVPDE 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 24644901 192 IEFWQGQTDRLHDRIRFRRgggvesevdsklvhKGEDGWVYERLAP 237
Cdd:TIGR00558 159 IEFWQGRPSRLHDRFRYRR--------------DGDGSWRIERLAP 190
|
|
| PdxH |
COG0259 |
Pyridoxine/pyridoxamine 5'-phosphate oxidase [Coenzyme transport and metabolism]; Pyridoxine ... |
10-237 |
1.22e-95 |
|
Pyridoxine/pyridoxamine 5'-phosphate oxidase [Coenzyme transport and metabolism]; Pyridoxine/pyridoxamine 5'-phosphate oxidase is part of the Pathway/BioSystem: Pyridoxal phosphate biosynthesis
Pssm-ID: 440029 Cd Length: 212 Bit Score: 278.61 E-value: 1.22e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 10 LSALRLKYceRKDAFLEDNIKvKNPFCVFRDWLELALKTpEILEPNAAALATVSAEGRPSNRYVLVKEATAEGFTFFTNY 89
Cdd:COG0259 4 LADLRREY--TKGGLDESDLP-ADPLALFARWLEEAEAA-GVPEPNAMTLATVDADGRPSARTVLLKGVDERGFVFYTNY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 90 GSRKAEDIKSNPYVAISFYWLPLRRSVRIEGVAEKISVEDSLKYFHQRPRASQIGAAASPQSQRIPSRSYLDDVEAAIKL 169
Cdd:COG0259 80 ESRKGRELAANPRAALTFFWPELERQVRIEGRVEKVSAAESDAYFASRPRGSQLGAWASPQSQPIASREELEARFAELEA 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24644901 170 ELgPDGEVPLP-NWGGYLVRPDLIEFWQGQTDRLHDRIRFRRGGGvesevdsklvhkgedGWVYERLAP 237
Cdd:COG0259 160 RF-AGGDVPRPpHWGGYRVVPDRIEFWQGRPSRLHDRLRYTREDG---------------GWTIERLAP 212
|
|
| PRK05679 |
PRK05679 |
pyridoxal 5'-phosphate synthase; |
33-237 |
5.50e-87 |
|
pyridoxal 5'-phosphate synthase;
Pssm-ID: 235555 Cd Length: 195 Bit Score: 255.92 E-value: 5.50e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 33 NPFCVFRDWLELALKTpEILEPNAAALATVSAEGRPSNRYVLVKEATAEGFTFFTNYGSRKAEDIKSNPYVAISFYWLPL 112
Cdd:PRK05679 7 EPLALFERWLAEAVKA-ELNDPNAMTLATVDEDGRPSQRIVLLKGFDERGFVFYTNYESRKGRQLAANPKAALLFPWKSL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 113 RRSVRIEGVAEKISVEDSLKYFHQRPRASQIGAAASPQSQRIPSRSYLDDVEAAIKLELGpDGEVPLP-NWGGYLVRPDL 191
Cdd:PRK05679 86 ERQVRVEGRVEKVSAEESDAYFASRPRGSQIGAWASKQSRPISSRAALEAKFAEVKAKFA-QGEVPRPpHWGGYRVVPES 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 24644901 192 IEFWQGQTDRLHDRIRFRRGGGvesevdsklvhkgedGWVYERLAP 237
Cdd:PRK05679 165 IEFWQGRPSRLHDRILYRRDDG---------------GWKIERLAP 195
|
|
| PLN03049 |
PLN03049 |
pyridoxine (pyridoxamine) 5'-phosphate oxidase; Provisional |
5-237 |
1.95e-72 |
|
pyridoxine (pyridoxamine) 5'-phosphate oxidase; Provisional
Pssm-ID: 215550 [Multi-domain] Cd Length: 462 Bit Score: 227.81 E-value: 1.95e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 5 ASEVPLSALRLKYCERKdaFLEDNIKvKNPFCVFRDWLELALkTPEILEPNAAALATVSAEGRPSNRYVLVKEATAEGFT 84
Cdd:PLN03049 244 TPSVDIAALRENYVGPE--LLEEQVN-ADPIDQFKEWFDDAV-AAGLREPNAMTLATAGEDGRPSARIVLLKGVDKRGFV 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 85 FFTNYGSRKAEDIKSNPYVAISFYWLPLRRSVRIEGVAEKISVEDSLKYFHQRPRASQIGAAASPQSQRIPSRSYLDDVE 164
Cdd:PLN03049 320 WYTNYDSRKAHELSANPKASLVFYWDGLHRQVRVEGSVEKVSEEESDQYFHSRPRGSQIGALVSKQSTVIPGRHILDQSY 399
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24644901 165 AAIKLELGPDGEVPLP-NWGGYLVRPDLIEFWQGQTDRLHDRIRFRRgggveSEVDSKLVhkgedgWVYERLAP 237
Cdd:PLN03049 400 KELEAKYADSSAIPKPkHWGGYRLKPELIEFWQGRESRLHDRLQYTR-----EEINGKSV------WKIDRLAP 462
|
|
| PLN02918 |
PLN02918 |
pyridoxine (pyridoxamine) 5'-phosphate oxidase |
5-237 |
3.78e-58 |
|
pyridoxine (pyridoxamine) 5'-phosphate oxidase
Pssm-ID: 215496 [Multi-domain] Cd Length: 544 Bit Score: 192.46 E-value: 3.78e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 5 ASEVPLSALRLKYCERKdaFLEDNIKVkNPFCVFRDWLELALkTPEILEPNAAALATVSAEGRPSNRYVLVKEATAEGFT 84
Cdd:PLN02918 326 PPSVDISALRENYISPE--LLEEQVET-DPTDQFRKWFDEAV-AAGLREPNAMALSTANKDGKPSSRMVLLKGVDKNGFV 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 85 FFTNYGSRKAEDIKSNPYVAISFYWLPLRRSVRIEGVAEKISVEDSLKYFHQRPRASQIGAAASPQSQRIPSRSYLDDVE 164
Cdd:PLN02918 402 WYTNYESQKGSDLSENPSAALLFYWEELNRQVRVEGSVQKVPESESENYFHSRPRGSQIGAIVSKQSSVVPGRHVLYQEY 481
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24644901 165 AAIKLELGPDGEVPLP-NWGGYLVRPDLIEFWQGQTDRLHDRIRFrrgggVESEVDSKLVhkgedgWVYERLAP 237
Cdd:PLN02918 482 KELEKKYSDGSVIPKPkNWGGYRLKPNLFEFWQGQQSRLHDRLQY-----SLQEVNGKPV------WKIHRLAP 544
|
|
| phena_PhzG |
NF038138 |
phenazine biosynthesis FMN-dependent oxidase PhzG; |
33-237 |
1.27e-46 |
|
phenazine biosynthesis FMN-dependent oxidase PhzG;
Pssm-ID: 468380 Cd Length: 205 Bit Score: 153.67 E-value: 1.27e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 33 NPFCVFRDWLELAlKTPEILEPNAAALATVSAEGRPSNRYVLVKEATAEGFTFFTNYGSRKAEDIKSNPYVAISFYWLPL 112
Cdd:NF038138 19 EPLGLLRRWLEAA-VALGVREPRALALATADADGRPSTRIVVVKEVSDRGLVFTTHAGSRKGRELAANPWASGVLYWRET 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 113 RRSVRIEGVAEKISVEDSLKYFHQRPRASQIGAAASPQSQRipsrsyLDDVEA--AIKLELGPDGEvPLP---NWGGYLV 187
Cdd:NF038138 98 SQQISLSGPVERLPDAESDALWAARPVATHAMTAASRQSEP------LDDEAAlrAEARELAEAGG-PLPrpaRFVGYRL 170
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 24644901 188 RPDLIEFWQGQTDRLHDRIRFRRGGgvesevdsklvhkgeDGWVYERLAP 237
Cdd:NF038138 171 VPEEVEFWAAGPDRLHRRLRYDRDG---------------DGWTHVRLQP 205
|
|
| Putative_PNPOx |
pfam01243 |
Pyridoxamine 5'-phosphate oxidase; Family of domains with putative PNPOx function. Family ... |
50-126 |
4.57e-24 |
|
Pyridoxamine 5'-phosphate oxidase; Family of domains with putative PNPOx function. Family members were predicted to encode pyridoxamine 5'-phosphate oxidase, based on sequence similarity. However, there is no experimental data to validate the predicted activity and purified proteins, such as Swiss:Q06199 and its paralogs, do not possess this activity, nor do they bind to flavin mononucleotide (FMN). To date, the only time functional oxidase activity has been experimentally demonstrated is when the sequences contain both pfam01243 and pfam10590. Moreover, some of the family members that contain both domains have been shown to be involved in phenazine biosynthesis. While some molecular function has been experimentally validated for the proteins containing both domains, the role performed by each domain on its own is unknown.
Pssm-ID: 426149 [Multi-domain] Cd Length: 88 Bit Score: 91.54 E-value: 4.57e-24
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24644901 50 EILEPNAAALATVSAEGRPSNRYVLVKEATAE-GFTFFTNYGSRKAEDIKSNPYVAISFYWLPLRRSVRIEGVAEKIS 126
Cdd:pfam01243 8 FLAEPNAVVLATVDKDGRPNVRPVGLKYGFDTvGILFATNTDSRKARNLEENPRVALLFGDPELRRGVRIEGTAEIVT 85
|
|
| PNP_phzG_C |
pfam10590 |
Pyridoxine 5'-phosphate oxidase C-terminal dimerization region; This domain represents one of ... |
182-237 |
3.13e-20 |
|
Pyridoxine 5'-phosphate oxidase C-terminal dimerization region; This domain represents one of the two dimerization regions of the protein, located at the edge of the dimer interface, at the C-terminus, being the last three beta strands, S6, S7, and S8 along with the last three residues to the end. In Swiss:P21159, S6 runs from residues 178-192, S7 from 200-206 and S8 from 211-215. the extended loop, of residues 167-177 may well be involved in the pocket formed between the two dimers that positions the FMN molecule.To date, the only time functional oxidase or phenazine biosynthesis activities have been experimentally demonstrated is when the sequences contain both pfam01243 and pfam10590. It is unknown the role performed by each domain in bringing about molecular functions of either oxidase or phenazine activity.
Pssm-ID: 463161 Cd Length: 42 Bit Score: 80.24 E-value: 3.13e-20
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 24644901 182 WGGYLVRPDLIEFWQGQTDRLHDRIRFRRgggvesevdsklvhKGEDGWVYERLAP 237
Cdd:pfam10590 1 WGGYRLVPEEIEFWQGRPSRLHDRIRYTR--------------EGDGGWTIERLAP 42
|
|
| YzzA |
COG3871 |
General stress protein 26 (function unknown) [Function unknown]; |
50-123 |
7.58e-09 |
|
General stress protein 26 (function unknown) [Function unknown];
Pssm-ID: 443080 [Multi-domain] Cd Length: 132 Bit Score: 52.63 E-value: 7.58e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24644901 50 EILE-PNAAALATVSAEGRPSNRYVLVKEATAEG-FTFFTNYGSRKAEDIKSNPYVAISFYWLPLRRSVRIEGVAE 123
Cdd:COG3871 13 ELLEdIRTAMLATVDADGRPHSRPMWFQVDVDDGtLWFFTSRDSAKVRNIRRDPRVSLSFADPGDDRYVSVEGTAE 88
|
|
| COG5135 |
COG5135 |
Uncharacterized conserved protein [Function unknown]; |
59-194 |
1.78e-06 |
|
Uncharacterized conserved protein [Function unknown];
Pssm-ID: 444058 Cd Length: 193 Bit Score: 46.87 E-value: 1.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 59 LATVSAEGRPSNRYVLVKeataeGFT-------FFTNYGSRKAEDIKSNPYVAISFYWLPLRRSVRIEGVAEKISVEDSL 131
Cdd:COG5135 27 LATVTGDGRPANRTVVFR-----GFLedsnqlkFITDARSEKVDQIQQQPWAEICWYFPKTREQFRLSGKLTLVTADDPD 101
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24644901 132 KYFHQ---------RPRASQIGAAASPQSQRipsrsylDDVEAAIKLELgPDGEVPLPNWGGYLVRPDLIEF 194
Cdd:COG5135 102 PDLQKarqqtwqelSDAARLQFAWPAPGAPR-------EEPEAAFSPPP-PDPDQPLPNFCLLLLEPDQVDH 165
|
|
| Pyridox_oxase_2 |
pfam12766 |
Pyridoxamine 5'-phosphate oxidase; Pyridoxamine 5'-phosphate oxidase catalyzes the oxidation ... |
39-126 |
6.82e-04 |
|
Pyridoxamine 5'-phosphate oxidase; Pyridoxamine 5'-phosphate oxidase catalyzes the oxidation of pyridoxamine-5-P (PMP) and pyridoxine-5-P (PNP) to pyridoxal-5-P (PLP), the terminal step in the de novo biosynthesis of PLP in Escherichia coli and part of the salvage pathway of this coenzyme in both E. coli and mammalian cells. This region is the flavoprotein FMN-binding domain.
Pssm-ID: 432768 [Multi-domain] Cd Length: 99 Bit Score: 37.99 E-value: 6.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644901 39 RDWLELALKTPEILEP-NAAALATV-SAEGRPSNRYV-----LVKEATAEGFTFFTNYGSRKAEDIKSNPYVAISFyWLP 111
Cdd:pfam12766 5 RPLLESALSNNRKLPPsTYFQLATVdPPEGRPRVRTVvfrgfLFNDYESDVLTFTTDVRSEKVEQLEGNPAFEACF-WFP 83
|
90
....*....|....*.
gi 24644901 112 -LRRSVRIEGVAEKIS 126
Cdd:pfam12766 84 kTREQFRIRGTAFVIG 99
|
|
|