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Conserved domains on  [gi|24644255|ref|NP_730939|]
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sodium potassium chloride cotransporter, isoform A [Drosophila melanogaster]

Protein Classification

APC family permease( domain architecture ID 1903533)

APC (amino acid/polyamine/organocation) family permease is involved in the uptake of a specific amino acid and/or polyamine substrate with the concomitant import of a proton

Gene Ontology:  GO:0055085|GO:0022857
TCDB:  2.A.3

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
AA_permease_2 super family cl45918
Amino acid permease;
13-995 0e+00

Amino acid permease;


The actual alignment was detected with superfamily member TIGR00930:

Pssm-ID: 459263 [Multi-domain]  Cd Length: 953  Bit Score: 1032.74  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255    13 HQESLPRLDNYRISM----RNLKRPSIGELQGE---------------AVDQSITIPEPEPEATGGH-------IKLGWI 66
Cdd:TIGR00930   2 TVDAVPRIEHYRNSEgqggPKRNRPSLEELHDLldkvvsllgpladytNNGQGMKEHEEAEDAEGTKekppagaVKFGWV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255    67 VGVLIPCLLNIWGVMLFLRLSWVVAESGILQSLIIITISAVVCVITTLSLSAISTNGEVKGGGVYFIISRSLGPEFGASV 146
Cdd:TIGR00930  82 MGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGSI 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   147 GVVFAFANAVSASMNTIGFCESLNVLLKNNDLKIVDNGINDIRIVGSITVLVLILICCVGMEWETKAQNFLIVTIVLAIF 226
Cdd:TIGR00930 162 GLIFAFANAVAVAMYVVGFAETVLDLLRENGSKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLFLVIVLLSIL 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   227 NFLIGAAIGPqgnEEQISRGFVGFSWATLKENFGSDYRYAEGvnhDFFSVFAIFFPSVTGIQAGANICGDLKDAGAAIPK 306
Cdd:TIGR00930 242 NIFVGTIIPA---FDKPAKGFFGLGNEIFSENFIPGIPGPEG---GFFSLFGIFFPSVTGILAGANISGDLKDPQKAIPK 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   307 GTFWSLLISMSSYALFVLFAGGAAVRDASGIPADLV--NGTIVSSELPCmATGNCTWGLFNSYEMMQEMSLWGPLIYAGC 384
Cdd:TIGR00930 316 GTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLvtNCTSAACFSEC-AHNTCSYGLMNNLQVMSLVSPFPPLITAGI 394
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   385 FAATLSTALTNLLSVPRLVQALGIDQIYPGLIFFSKPYGKHGEPYRGYVLTFFITTGFLLIGELNLIAPLISTFYLASYA 464
Cdd:TIGR00930 395 FSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGKNGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLASYA 474
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   465 LINFCTFHAAFVKPLGWRPTFKYYNAWLSLFGFAMCVAIMFLINYVAAIITFGIIFALYLVVMYRKPEANWGSTTQAQQY 544
Cdd:TIGR00930 475 LINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVNWGSSTQALSY 554
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   545 KAALMAVHRLQNVSDHVKNYHPQVLVLSGDPKTRPPLVDFGYLLTKNNSLMFVANII--PVRVGYKNRQHLVKDGQKYLD 622
Cdd:TIGR00930 555 SLALYSLLRLEEVEDHVKNWRPQCLVLTGPPVCRPALLDFASQFTKGKGLMICGSVIqgPRLECVKEAQAAEAKIQTWLE 634
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   623 ARKIKAFYNVIDGFSLEDGINALTKSTGFGKMSPNIVLVGYKPDWNRCRKEEVESYFSILYNAFSQRMGVALLRLPNGLD 702
Cdd:TIGR00930 635 KNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAEPRAWETYIGIIHDAFDAHLAVVVVRNSEGLP 714
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   703 FSELSSEVTLPANgmghmhtanahgftnelmpaanaasellhidsnlnlasmdspnssftmpqpapmpnmqrnsrsykvt 782
Cdd:TIGR00930 715 ISVLQVQEELEND------------------------------------------------------------------- 727
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   783 sSDEPAVTYHTKGGSDIPQNLLDAMTIFTRKQPKGTIDVFWLYDDGGLTILLPYIISMRSHWQNSKLRVFAMCHGKDE-E 861
Cdd:TIGR00930 728 -CSEDSIELNDGKISTQPDMHLEASTQFQKKQGKGTIDVWWLVDDGGLTLLLPYLLTTKKVWKKCKIRIFVGAQKDDRsE 806
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   862 QEEKSMASLLTKFRIKYSELIMLKGVSEQPRADTVLKHKRLIEPFR-------RGARNEFG-------ITDDELQSMSEK 927
Cdd:TIGR00930 807 QEKKDMATLLYKFRIDAEVIVVLMDINAKPQTESMEAFEEMIRPFRlhktekdREAKDPKMtwtkpwkITDAELQSNVRK 886
                         970       980       990      1000      1010      1020
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24644255   928 TNRQLRIHELVVKHSSNASLVVMSLPMPRKEAISAPLYMSWLEMLTSDMKcPVALARGNQTPVLTLYS 995
Cdd:TIGR00930 887 SYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLP-PVLLVRGNHRNVLTFYS 953
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
13-995 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1032.74  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255    13 HQESLPRLDNYRISM----RNLKRPSIGELQGE---------------AVDQSITIPEPEPEATGGH-------IKLGWI 66
Cdd:TIGR00930   2 TVDAVPRIEHYRNSEgqggPKRNRPSLEELHDLldkvvsllgpladytNNGQGMKEHEEAEDAEGTKekppagaVKFGWV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255    67 VGVLIPCLLNIWGVMLFLRLSWVVAESGILQSLIIITISAVVCVITTLSLSAISTNGEVKGGGVYFIISRSLGPEFGASV 146
Cdd:TIGR00930  82 MGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGSI 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   147 GVVFAFANAVSASMNTIGFCESLNVLLKNNDLKIVDNGINDIRIVGSITVLVLILICCVGMEWETKAQNFLIVTIVLAIF 226
Cdd:TIGR00930 162 GLIFAFANAVAVAMYVVGFAETVLDLLRENGSKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLFLVIVLLSIL 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   227 NFLIGAAIGPqgnEEQISRGFVGFSWATLKENFGSDYRYAEGvnhDFFSVFAIFFPSVTGIQAGANICGDLKDAGAAIPK 306
Cdd:TIGR00930 242 NIFVGTIIPA---FDKPAKGFFGLGNEIFSENFIPGIPGPEG---GFFSLFGIFFPSVTGILAGANISGDLKDPQKAIPK 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   307 GTFWSLLISMSSYALFVLFAGGAAVRDASGIPADLV--NGTIVSSELPCmATGNCTWGLFNSYEMMQEMSLWGPLIYAGC 384
Cdd:TIGR00930 316 GTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLvtNCTSAACFSEC-AHNTCSYGLMNNLQVMSLVSPFPPLITAGI 394
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   385 FAATLSTALTNLLSVPRLVQALGIDQIYPGLIFFSKPYGKHGEPYRGYVLTFFITTGFLLIGELNLIAPLISTFYLASYA 464
Cdd:TIGR00930 395 FSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGKNGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLASYA 474
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   465 LINFCTFHAAFVKPLGWRPTFKYYNAWLSLFGFAMCVAIMFLINYVAAIITFGIIFALYLVVMYRKPEANWGSTTQAQQY 544
Cdd:TIGR00930 475 LINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVNWGSSTQALSY 554
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   545 KAALMAVHRLQNVSDHVKNYHPQVLVLSGDPKTRPPLVDFGYLLTKNNSLMFVANII--PVRVGYKNRQHLVKDGQKYLD 622
Cdd:TIGR00930 555 SLALYSLLRLEEVEDHVKNWRPQCLVLTGPPVCRPALLDFASQFTKGKGLMICGSVIqgPRLECVKEAQAAEAKIQTWLE 634
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   623 ARKIKAFYNVIDGFSLEDGINALTKSTGFGKMSPNIVLVGYKPDWNRCRKEEVESYFSILYNAFSQRMGVALLRLPNGLD 702
Cdd:TIGR00930 635 KNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAEPRAWETYIGIIHDAFDAHLAVVVVRNSEGLP 714
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   703 FSELSSEVTLPANgmghmhtanahgftnelmpaanaasellhidsnlnlasmdspnssftmpqpapmpnmqrnsrsykvt 782
Cdd:TIGR00930 715 ISVLQVQEELEND------------------------------------------------------------------- 727
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   783 sSDEPAVTYHTKGGSDIPQNLLDAMTIFTRKQPKGTIDVFWLYDDGGLTILLPYIISMRSHWQNSKLRVFAMCHGKDE-E 861
Cdd:TIGR00930 728 -CSEDSIELNDGKISTQPDMHLEASTQFQKKQGKGTIDVWWLVDDGGLTLLLPYLLTTKKVWKKCKIRIFVGAQKDDRsE 806
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   862 QEEKSMASLLTKFRIKYSELIMLKGVSEQPRADTVLKHKRLIEPFR-------RGARNEFG-------ITDDELQSMSEK 927
Cdd:TIGR00930 807 QEKKDMATLLYKFRIDAEVIVVLMDINAKPQTESMEAFEEMIRPFRlhktekdREAKDPKMtwtkpwkITDAELQSNVRK 886
                         970       980       990      1000      1010      1020
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24644255   928 TNRQLRIHELVVKHSSNASLVVMSLPMPRKEAISAPLYMSWLEMLTSDMKcPVALARGNQTPVLTLYS 995
Cdd:TIGR00930 887 SYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLP-PVLLVRGNHRNVLTFYS 953
SLC12 pfam03522
Solute carrier family 12;
578-995 0e+00

Solute carrier family 12;


Pssm-ID: 460955  Cd Length: 414  Bit Score: 560.31  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   578 RPPLVDFGYLLTKNNSLMFVANIIPVRVGYKNRQHLVKDGQKYLDARKIKAFYNVIDGFSLEDGINALTKSTGFGKMSPN 657
Cdd:pfam03522   1 RPALVDFAHLITKNVSLMICGHVVKGRLSQKLRSELQKKAYRWLRKRKIKAFYALVDGDNLREGAQALLQASGLGKLKPN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   658 IVLVGYKPDWNRCRKEEVESYFSILYNAFSQRMGVALLRLPNGLDFSELSSEVTLPANGMGHMHTANahgfTNELMPAAN 737
Cdd:pfam03522  81 ILLMGYKSDWRTCDKEELEEYFNVIHDAFDLQYAVAILRLPEGLDVSHLLQDQDTEELGLGDETNSS----YAEQSSEEQ 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   738 AASELLHIDSNLNLASMDSpNSSFTMPQPAPMPNMQRNSRSYKVTSSDEPavtyHTKGGSDIPQNLLDAMTIFTRKQPKG 817
Cdd:pfam03522 157 STSNSKQDDDKSKLSKKDS-NLSLSPDKSTKNPSGKDSSKSDKLKKKSPS----IILRTASNEKEILNNITQFQKKQKKG 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   818 TIDVFWLYDDGGLTILLPYIISMRSHWQNSKLRVFAMCHGKDE-EQEEKSMASLLTKFRIKYSELIMLKGVSEQPRADTV 896
Cdd:pfam03522 232 TIDVWWLYDDGGLTLLLPYILSTRSKWSDCKLRVFALGNRKDElEEEQRNMASLLSKFRIDYSDLTVIPDITKKPKKETK 311
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   897 LKHKRLIEPFRRGARNEFG-----ITDDELQSMSEKTNRQLRIHELVVKHSSNASLVVMSLPMPRKEAISAPLYMSWLEM 971
Cdd:pfam03522 312 KFFDELIEPFRLHEDDKEEesaekITDSELEALKEKTNRQLRLRELLLEHSSDANLIVMTLPMPRKGTVSAPLYMAWLET 391
                         410       420
                  ....*....|....*....|....
gi 24644255   972 LTSDMkCPVALARGNQTPVLTLYS 995
Cdd:pfam03522 392 LTKDL-PPFLLVRGNQTSVLTFYS 414
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
62-533 4.97e-38

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 148.12  E-value: 4.97e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255  62 KLGWIVGVLIpCLLNIWGVMLFLRLSWVVAESGiLQSLIIITISAVVCVITTLSLSAISTNgEVKGGGVYFIISRSLGPE 141
Cdd:COG0531  12 KLGLFDLVAL-GVGAIIGAGIFVLPGLAAGLAG-PAAILAWLIAGLLALLVALSYAELASA-FPRAGGAYTYARRALGPL 88
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255 142 FGASVGVVFAFANAVSASMNTIGFCESLNVLLknndlkivdnGINDIRIVGSITVLVLILICCVGMEWETKAQNFLIVTI 221
Cdd:COG0531  89 LGFLAGWALLLSYVLAVAAVAVAFGGYLSSLF----------PAGGSVLIALVLILLLTLLNLRGVKESAKVNNILTVLK 158
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255 222 VLAIFNFLIGaaigpqgneeqisrGFVGFSWATLkENFGSDYRYAEGVnhdfFSVFAIFFPSVTGIQAGANICGDLKDAG 301
Cdd:COG0531 159 LLVLLLFIVV--------------GLFAFDPANF-TPFLPAGGGLSGV----LAALALAFFAFTGFEAIANLAEEAKNPK 219
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255 302 AAIPKGTFWSLLISMSSYALFVLFAGGAavrdasgIPADlvngTIVSSELPcmatgnctwglfnSYEMMQEM--SLWGPL 379
Cdd:COG0531 220 RNIPRAIILSLLIVGVLYILVSLALTGV-------VPYD----ELAASGAP-------------LADAAEAVfgPWGAIL 275
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255 380 IYAGCFAATLSTALTNLLSVPRLVQALGIDQIYPGliFFSKPYGKHGEPYRGYVLTFFITTGFLLIGE--LNLIAPLIST 457
Cdd:COG0531 276 IALGALLSLLGALNASILGASRLLYAMARDGLLPK--VFAKVHPRFGTPVNAILLTGVIALLLLLLGAasFTALASLASV 353
                       410       420       430       440       450       460       470
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24644255 458 FYLASYALINFCTFHAAFVKPLGWRPtFKYYNAWLSLFGFAMCVAIMFLINYVAAIITFGII---FALYLVVMYRKPEA 533
Cdd:COG0531 354 GVLLAYLLVALAVIVLRRRRPDLPRP-FRVPLPLIPILGILLCLFLLYLLGPGALLIGLVLLaigLLLYLLYRRRHPKL 431
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
13-995 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1032.74  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255    13 HQESLPRLDNYRISM----RNLKRPSIGELQGE---------------AVDQSITIPEPEPEATGGH-------IKLGWI 66
Cdd:TIGR00930   2 TVDAVPRIEHYRNSEgqggPKRNRPSLEELHDLldkvvsllgpladytNNGQGMKEHEEAEDAEGTKekppagaVKFGWV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255    67 VGVLIPCLLNIWGVMLFLRLSWVVAESGILQSLIIITISAVVCVITTLSLSAISTNGEVKGGGVYFIISRSLGPEFGASV 146
Cdd:TIGR00930  82 MGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGSI 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   147 GVVFAFANAVSASMNTIGFCESLNVLLKNNDLKIVDNGINDIRIVGSITVLVLILICCVGMEWETKAQNFLIVTIVLAIF 226
Cdd:TIGR00930 162 GLIFAFANAVAVAMYVVGFAETVLDLLRENGSKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLFLVIVLLSIL 241
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   227 NFLIGAAIGPqgnEEQISRGFVGFSWATLKENFGSDYRYAEGvnhDFFSVFAIFFPSVTGIQAGANICGDLKDAGAAIPK 306
Cdd:TIGR00930 242 NIFVGTIIPA---FDKPAKGFFGLGNEIFSENFIPGIPGPEG---GFFSLFGIFFPSVTGILAGANISGDLKDPQKAIPK 315
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   307 GTFWSLLISMSSYALFVLFAGGAAVRDASGIPADLV--NGTIVSSELPCmATGNCTWGLFNSYEMMQEMSLWGPLIYAGC 384
Cdd:TIGR00930 316 GTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLvtNCTSAACFSEC-AHNTCSYGLMNNLQVMSLVSPFPPLITAGI 394
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   385 FAATLSTALTNLLSVPRLVQALGIDQIYPGLIFFSKPYGKHGEPYRGYVLTFFITTGFLLIGELNLIAPLISTFYLASYA 464
Cdd:TIGR00930 395 FSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGKNGEPLRAYLLTAFIAEGFILIAELNTIAPIISNFFLASYA 474
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   465 LINFCTFHAAFVKPLGWRPTFKYYNAWLSLFGFAMCVAIMFLINYVAAIITFGIIFALYLVVMYRKPEANWGSTTQAQQY 544
Cdd:TIGR00930 475 LINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDVNWGSSTQALSY 554
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   545 KAALMAVHRLQNVSDHVKNYHPQVLVLSGDPKTRPPLVDFGYLLTKNNSLMFVANII--PVRVGYKNRQHLVKDGQKYLD 622
Cdd:TIGR00930 555 SLALYSLLRLEEVEDHVKNWRPQCLVLTGPPVCRPALLDFASQFTKGKGLMICGSVIqgPRLECVKEAQAAEAKIQTWLE 634
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   623 ARKIKAFYNVIDGFSLEDGINALTKSTGFGKMSPNIVLVGYKPDWNRCRKEEVESYFSILYNAFSQRMGVALLRLPNGLD 702
Cdd:TIGR00930 635 KNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQAEPRAWETYIGIIHDAFDAHLAVVVVRNSEGLP 714
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   703 FSELSSEVTLPANgmghmhtanahgftnelmpaanaasellhidsnlnlasmdspnssftmpqpapmpnmqrnsrsykvt 782
Cdd:TIGR00930 715 ISVLQVQEELEND------------------------------------------------------------------- 727
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   783 sSDEPAVTYHTKGGSDIPQNLLDAMTIFTRKQPKGTIDVFWLYDDGGLTILLPYIISMRSHWQNSKLRVFAMCHGKDE-E 861
Cdd:TIGR00930 728 -CSEDSIELNDGKISTQPDMHLEASTQFQKKQGKGTIDVWWLVDDGGLTLLLPYLLTTKKVWKKCKIRIFVGAQKDDRsE 806
                         890       900       910       920       930       940       950       960
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   862 QEEKSMASLLTKFRIKYSELIMLKGVSEQPRADTVLKHKRLIEPFR-------RGARNEFG-------ITDDELQSMSEK 927
Cdd:TIGR00930 807 QEKKDMATLLYKFRIDAEVIVVLMDINAKPQTESMEAFEEMIRPFRlhktekdREAKDPKMtwtkpwkITDAELQSNVRK 886
                         970       980       990      1000      1010      1020
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24644255   928 TNRQLRIHELVVKHSSNASLVVMSLPMPRKEAISAPLYMSWLEMLTSDMKcPVALARGNQTPVLTLYS 995
Cdd:TIGR00930 887 SYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDLP-PVLLVRGNHRNVLTFYS 953
SLC12 pfam03522
Solute carrier family 12;
578-995 0e+00

Solute carrier family 12;


Pssm-ID: 460955  Cd Length: 414  Bit Score: 560.31  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   578 RPPLVDFGYLLTKNNSLMFVANIIPVRVGYKNRQHLVKDGQKYLDARKIKAFYNVIDGFSLEDGINALTKSTGFGKMSPN 657
Cdd:pfam03522   1 RPALVDFAHLITKNVSLMICGHVVKGRLSQKLRSELQKKAYRWLRKRKIKAFYALVDGDNLREGAQALLQASGLGKLKPN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   658 IVLVGYKPDWNRCRKEEVESYFSILYNAFSQRMGVALLRLPNGLDFSELSSEVTLPANGMGHMHTANahgfTNELMPAAN 737
Cdd:pfam03522  81 ILLMGYKSDWRTCDKEELEEYFNVIHDAFDLQYAVAILRLPEGLDVSHLLQDQDTEELGLGDETNSS----YAEQSSEEQ 156
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   738 AASELLHIDSNLNLASMDSpNSSFTMPQPAPMPNMQRNSRSYKVTSSDEPavtyHTKGGSDIPQNLLDAMTIFTRKQPKG 817
Cdd:pfam03522 157 STSNSKQDDDKSKLSKKDS-NLSLSPDKSTKNPSGKDSSKSDKLKKKSPS----IILRTASNEKEILNNITQFQKKQKKG 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   818 TIDVFWLYDDGGLTILLPYIISMRSHWQNSKLRVFAMCHGKDE-EQEEKSMASLLTKFRIKYSELIMLKGVSEQPRADTV 896
Cdd:pfam03522 232 TIDVWWLYDDGGLTLLLPYILSTRSKWSDCKLRVFALGNRKDElEEEQRNMASLLSKFRIDYSDLTVIPDITKKPKKETK 311
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   897 LKHKRLIEPFRRGARNEFG-----ITDDELQSMSEKTNRQLRIHELVVKHSSNASLVVMSLPMPRKEAISAPLYMSWLEM 971
Cdd:pfam03522 312 KFFDELIEPFRLHEDDKEEesaekITDSELEALKEKTNRQLRLRELLLEHSSDANLIVMTLPMPRKGTVSAPLYMAWLET 391
                         410       420
                  ....*....|....*....|....
gi 24644255   972 LTSDMkCPVALARGNQTPVLTLYS 995
Cdd:pfam03522 392 LTKDL-PPFLLVRGNQTSVLTFYS 414
AA_permease pfam00324
Amino acid permease;
68-569 4.53e-84

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 279.59  E-value: 4.53e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255    68 GVLIPCLLNIWGVMLFLRLSWVVAESGILQSLIIITISAVVCVITTLSLSAISTNGeVKGGGVYFIISRSLGPEFGASVG 147
Cdd:pfam00324   1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNG-PVSGGFYTYASRFLGPSLGFATG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   148 V------VFAFANAVSASMNTIGFCESLNvllknndlkivdnGINDIRIVGSITVLVLILICCVGMEWETKAQNFLIVTI 221
Cdd:pfam00324  80 WnywlswITVLALELTAASILIQFWELVP-------------DIPYLWVWGAVFLVLLTIINLVGVKWYGEAEFWFALIK 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   222 VLAIFNFLIGAAIGPQGNEEQISRGFVGFSWATLKENFGSDYryaegvNHDFFSVFAIFFPSVTGIQAGANICGDLKDAG 301
Cdd:pfam00324 147 IIAIIGFIIVGIILLSGGNPNDGAIFRYLGDNGGKNNFPPGF------GKGFISVFVIAFFAFTGIELVGIAAGEVKNPE 220
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   302 AAIPKGTFWSLLISMSSYALFVLFAGGAAVRDASGIPADLVNGTivsselpcmatgnctwGLFNSYEMMQEMSLWGPLIY 381
Cdd:pfam00324 221 KSIPKAILQVIWRITIFYILSLLAIGLLVPWNDPGLLNDSASAA----------------SPFVIFFKFLGISGLAPLIN 284
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   382 AGCFAATLSTALTNLLSVPRLVQALGIDQIYPgliFFSKPYGKHGEPYRGYVLTFFITTGFLLIGELNLIapLISTFYLA 461
Cdd:pfam00324 285 AVILTAALSAANSSLYSGSRMLYSLARDGLAP---KFLKKVDKRGVPLRAILVSMVISLLALLLASLNPA--IVFNFLLA 359
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   462 SYALINFCTFHAAFVKPLGWRPTFKYYNAWLSLFGFAMCVAIMFLINYVAAIITFGIIFALYLVVMYRKPEANWGSTTQA 541
Cdd:pfam00324 360 ISGLSGLIVWGLISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFA 439
                         490       500
                  ....*....|....*....|....*...
gi 24644255   542 QQYKAALMAVHRLQNVSDHVKNYHPQVL 569
Cdd:pfam00324 440 AAYLIVLLFLIILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
62-533 4.97e-38

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 148.12  E-value: 4.97e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255  62 KLGWIVGVLIpCLLNIWGVMLFLRLSWVVAESGiLQSLIIITISAVVCVITTLSLSAISTNgEVKGGGVYFIISRSLGPE 141
Cdd:COG0531  12 KLGLFDLVAL-GVGAIIGAGIFVLPGLAAGLAG-PAAILAWLIAGLLALLVALSYAELASA-FPRAGGAYTYARRALGPL 88
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255 142 FGASVGVVFAFANAVSASMNTIGFCESLNVLLknndlkivdnGINDIRIVGSITVLVLILICCVGMEWETKAQNFLIVTI 221
Cdd:COG0531  89 LGFLAGWALLLSYVLAVAAVAVAFGGYLSSLF----------PAGGSVLIALVLILLLTLLNLRGVKESAKVNNILTVLK 158
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255 222 VLAIFNFLIGaaigpqgneeqisrGFVGFSWATLkENFGSDYRYAEGVnhdfFSVFAIFFPSVTGIQAGANICGDLKDAG 301
Cdd:COG0531 159 LLVLLLFIVV--------------GLFAFDPANF-TPFLPAGGGLSGV----LAALALAFFAFTGFEAIANLAEEAKNPK 219
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255 302 AAIPKGTFWSLLISMSSYALFVLFAGGAavrdasgIPADlvngTIVSSELPcmatgnctwglfnSYEMMQEM--SLWGPL 379
Cdd:COG0531 220 RNIPRAIILSLLIVGVLYILVSLALTGV-------VPYD----ELAASGAP-------------LADAAEAVfgPWGAIL 275
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255 380 IYAGCFAATLSTALTNLLSVPRLVQALGIDQIYPGliFFSKPYGKHGEPYRGYVLTFFITTGFLLIGE--LNLIAPLIST 457
Cdd:COG0531 276 IALGALLSLLGALNASILGASRLLYAMARDGLLPK--VFAKVHPRFGTPVNAILLTGVIALLLLLLGAasFTALASLASV 353
                       410       420       430       440       450       460       470
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24644255 458 FYLASYALINFCTFHAAFVKPLGWRPtFKYYNAWLSLFGFAMCVAIMFLINYVAAIITFGII---FALYLVVMYRKPEA 533
Cdd:COG0531 354 GVLLAYLLVALAVIVLRRRRPDLPRP-FRVPLPLIPILGILLCLFLLYLLGPGALLIGLVLLaigLLLYLLYRRRHPKL 431
AA_permease_2 pfam13520
Amino acid permease;
90-526 3.40e-14

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 75.81  E-value: 3.40e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255    90 VAESGILQSLIIITISAVVCVITTLSLSAISTNGEVKGGGVYFIISRSLGPEFGASVGVVFAFANAVSASMNTIGFCESL 169
Cdd:pfam13520  24 LVASGGPALIVWGWIAAIIFSLAVGLVYAELSSALPRSGGIYVYLENAFGKFVAFLAGWSNWFAYVLGLASSASVAASYL 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   170 NVLLknnDLKIVDNGInDIRIVGSITVLVLILICCVGMEWETKAQNFLIVTIVLAIFNFLIGAAIgpqgneeqisrGFVG 249
Cdd:pfam13520 104 LSAL---GPDLVPTTW-LTYGIAIAILIIFAIINIRGVRESAKIQNILGILKLLLPLILIIILGL-----------VTAD 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   250 FSWATLKENFGsDYRYAEGVNHDFFSVFAIFFpSVTGIQAGANICGDLKDagAAIPKGTFWSLLISMSSYALFVLFAGGA 329
Cdd:pfam13520 169 GGGFNLLSGEW-HTFFPDGWPGVFAGFLGVLW-SFTGFESAANVSEEVKK--RNVPKAIFIGVIIVGVLYILVNIAFFGV 244
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   330 AVRDASGIPADLVNgtivsselpcmatgncTWGLFnsYEMMQemSLWGPLIYAGCFAATLSTALTNLL-SVPRLVQALGI 408
Cdd:pfam13520 245 VPDDEIALSSGLGQ----------------VAALL--FQAVG--GKWGAIIVVILLALSLLGAVNTAIvGASRLLYALAR 304
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644255   409 DQIYPGLIFFSKPyGKHGEPYRGYVLTFFITTGFLLI-----GELNLIAPLISTFYLASYALINFCTFHAAFVKPLGWRP 483
Cdd:pfam13520 305 DGVLPFSRFFAKV-NKFGSPIRAIILTAILSLILLLLfllspAAYNALLSLSAYGYLLSYLLPIIGLLILRKKRPDLGRI 383
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 24644255   484 TFKYYNAWLSLFGFAMCVAIMFLINYVAAIITFGIIFALYLVV 526
Cdd:pfam13520 384 PGRWPVAIFGILFSLFLIVALFFPPVGPATGSSLNYAIILIVA 426
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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