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Dis3 like 3'-5' exoribonuclease 2, isoform C [Drosophila melanogaster]
Protein Classification
ribonuclease R family protein ( domain architecture ID 11426128 )
ribonuclease R (RNaseR or RNR) family protein similar to RNR, a 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
List of domain hits
Name
Accession
Description
Interval
E-value
RNB
pfam00773 RNB domain; This domain is the catalytic domain of ribonuclease II.
560-909
1.75e-97
RNB domain; This domain is the catalytic domain of ribonuclease II.
Pssm-ID: 459934 [Multi-domain]
Cd Length: 314
Bit Score: 310.76
E-value: 1.75e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 560 RKDLR KMCIF TIDP MT A R DLDDA V S I EKL GDNE Y EI GVHI S DVSH FLIEDNE LD NIVKE R S TS I YL ANE VI H MLP QS L CM 639
Cdd:pfam00773 1 RKDLR DLPFI TIDP AD A K DLDDA I S V EKL PNGG Y RL GVHI A DVSH YVPPGSP LD REARK R G TS V YL PDR VI P MLP EK L SN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 640 R - CSL L PG Q D KF A F SV FWRMNGK G VM lq KKP E FCRT VI N S CSQFA YE HAQKIIDNPNE rftendfptiln GFNPD D IRNR 718
Cdd:pfam00773 81 D l CSL N PG E D RL A L SV EITIDAD G EV -- TSY E IYPS VI R S KARLT YE EVDDLLEGKDA ------------ EKDKP D LAED 146
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 719 VLW L HDI A SSI R KT RL DN GAL TINNAKLRFL LD P it GEPLSFEVEKQRE A NR LIEEFMLLAN Q AVAR FIHD s FPDI A VL R 798
Cdd:pfam00773 147 LRL L YEL A KIL R AK RL QR GAL DLDTPENKLI LD E -- EGVIDILIQERTD A HS LIEEFMLLAN E AVAR HLQE - LGIP A LY R 223
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 799 N HP P P LIKS L KA L REK L LA L GFELDY S S S KALQESMV RL cneapnpvamnac LS Q LL MKP M A RA T Y F csegkse P AD L W H 878
Cdd:pfam00773 224 V HP E P DLEK L NS L IKL L QL L PDDKGL S K S LEKIKDDE RL ------------- LS I LL LRT M P RA E Y S ------- P EP L G H 283
330 340 350
....*....|....*....|....*....|.
gi 24654592 879 YA L SIP IYTHFTSPIRRYPD IL VHR L L A A A L 909
Cdd:pfam00773 284 FG L GLD IYTHFTSPIRRYPD LI VHR Q L K A L L 314
OB_Dis3 super family
cl39334 Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 ...
454-530
8.28e-10
Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 protein. This domain along with CSD1 binds to RNA.
pfam17849 :Pssm-ID: 436091 [Multi-domain]
Cd Length: 77
Bit Score: 56.08
E-value: 8.28e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24654592 454 FYK F R P Y D L R V P MVYV P KDACAAHIGNKQQ i D VS G L L YLAH I LETDC N - GHCIAELIQPV G RV G NLDD E LK AIL FH NG 530
Cdd:pfam17849 1 YVL F V P R D K R I P RIRI P TKSAPEEFLENPE - D LE G K L FVVK I DDWPE N s RYPLGHIVKVL G EI G DIET E TE AIL LE NG 77
Name
Accession
Description
Interval
E-value
RNB
pfam00773 RNB domain; This domain is the catalytic domain of ribonuclease II.
560-909
1.75e-97
RNB domain; This domain is the catalytic domain of ribonuclease II.
Pssm-ID: 459934 [Multi-domain]
Cd Length: 314
Bit Score: 310.76
E-value: 1.75e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 560 RKDLR KMCIF TIDP MT A R DLDDA V S I EKL GDNE Y EI GVHI S DVSH FLIEDNE LD NIVKE R S TS I YL ANE VI H MLP QS L CM 639
Cdd:pfam00773 1 RKDLR DLPFI TIDP AD A K DLDDA I S V EKL PNGG Y RL GVHI A DVSH YVPPGSP LD REARK R G TS V YL PDR VI P MLP EK L SN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 640 R - CSL L PG Q D KF A F SV FWRMNGK G VM lq KKP E FCRT VI N S CSQFA YE HAQKIIDNPNE rftendfptiln GFNPD D IRNR 718
Cdd:pfam00773 81 D l CSL N PG E D RL A L SV EITIDAD G EV -- TSY E IYPS VI R S KARLT YE EVDDLLEGKDA ------------ EKDKP D LAED 146
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 719 VLW L HDI A SSI R KT RL DN GAL TINNAKLRFL LD P it GEPLSFEVEKQRE A NR LIEEFMLLAN Q AVAR FIHD s FPDI A VL R 798
Cdd:pfam00773 147 LRL L YEL A KIL R AK RL QR GAL DLDTPENKLI LD E -- EGVIDILIQERTD A HS LIEEFMLLAN E AVAR HLQE - LGIP A LY R 223
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 799 N HP P P LIKS L KA L REK L LA L GFELDY S S S KALQESMV RL cneapnpvamnac LS Q LL MKP M A RA T Y F csegkse P AD L W H 878
Cdd:pfam00773 224 V HP E P DLEK L NS L IKL L QL L PDDKGL S K S LEKIKDDE RL ------------- LS I LL LRT M P RA E Y S ------- P EP L G H 283
330 340 350
....*....|....*....|....*....|.
gi 24654592 879 YA L SIP IYTHFTSPIRRYPD IL VHR L L A A A L 909
Cdd:pfam00773 284 FG L GLD IYTHFTSPIRRYPD LI VHR Q L K A L L 314
VacB
COG0557 Exoribonuclease R [Transcription];
420-929
9.43e-95
Exoribonuclease R [Transcription];
Pssm-ID: 440323 [Multi-domain]
Cd Length: 711
Bit Score: 316.66
E-value: 9.43e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 420 P KAF V IA I TK R T e LRQI VG TISFTNP tklcddql F YKFR P Y D L R VPM - VYV P K D ACA - A HI G NK qqid V sglly LAH I LE 497
Cdd:COG0557 122 P EGR V VE I LE R A - NTRV VG RFEKEKG -------- F GFVV P D D K R LLQ d IFI P P D DLN g A KD G DL ---- V ----- VVE I TR 183
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 498 TDCNGH ciaeli Q P V GRV ---- G NLD D --- E LKAILFHN GL RDI kp F EQRFIDIYSQP P PPISQE DL RQ R K DLR KMCIF T 570
Cdd:COG0557 184 YPERRG ------ P P E GRV vevl G SPG D pga E ILIAIRKH GL PHE -- F PEEVLAEAEAL P DEVPEA DL KG R R DLR DLPLV T 255
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 571 ID PMT A R D L DDAVS I EKL GDNEYEI GVHI S DVSH FLIEDNE LD NIVKE R S TS I YL ANE VI H MLP QS L C - MR CSL L PG Q D K 649
Cdd:COG0557 256 ID GED A K D F DDAVS A EKL DNGGWRL GVHI A DVSH YVRPGSA LD REARK R G TS V YL PDR VI P MLP ER L S n GL CSL N PG E D R 335
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 650 F A F S VFWRMNG KG VM lq KKP EF C R T VI N S CSQFA YE HA Q K I I D NPN E RFT E ND fptilngfnp D D IRNRVLW L HDI A SSI 729
Cdd:COG0557 336 L A M S CEMEIDA KG EV -- VSY EF Y R S VI R S DARLT YE EV Q A I L D GKD E ELR E EY ---------- A D LVPMLEE L YEL A KIL 403
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 730 RK T R LDN GA LTINNAKLRFL LD P i T G E P LSFEVEKQRE A NR LIEEFMLLAN Q AVA R F IHDS fp DIAV L - R N H PP P LIKS L 808
Cdd:COG0557 404 RK A R EKR GA IDFDLPETKII LD E - E G K P EDIVPRERND A HK LIEEFMLLAN E AVA E F LEKL -- KLPF L y R V H EE P DPEK L 480
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 809 K ALRE K L LA LG FE L --- D YSSS K A LQ esmv R L CNEAPNPVAMNA c L SQ LL MKP M AR A T Y fcsegks E P ADLW H YA L SIPI 885
Cdd:COG0557 481 E ALRE F L AN LG LK L kgg D EPTP K D LQ ---- K L LEQVKGRPEEEL - L NT LL LRS M KQ A V Y ------- S P ENIG H FG L ALEA 548
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 24654592 886 YTHFTSPIRRYPD I LVHR L L A A A L KYCTP P KRTPDDLHT L TKL A 929
Cdd:COG0557 549 YTHFTSPIRRYPD L LVHR A L K A Y L EGKRS P GLQEYLEEE L EEI A 592
RNB
smart00955 This domain is the catalytic domain of ribonuclease II;
560-910
2.28e-92
This domain is the catalytic domain of ribonuclease II;
Pssm-ID: 214935 [Multi-domain]
Cd Length: 286
Bit Score: 296.10
E-value: 2.28e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 560 R K DLR KMCI FTIDP MT A R D L DDAVS I EKL GDNE Y EI GVHI S DVSH FLIEDNE LD NIVKE R S TS I YL ANE VI H MLP QS L CM 639
Cdd:smart00955 1 R V DLR DLPL FTIDP ED A K D I DDAVS V EKL DNGG Y RL GVHI A DVSH YVKPGSA LD REARK R G TS V YL PDR VI P MLP EE L SN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 640 - R CSL L PG Q D KF A F SV FWRMNGK G VMLQKK p EF C R T VI N S CSQFA YE HAQK I ID npnerftendfptilngfnpddirnr 718
Cdd:smart00955 81 g L CSL N PG E D RL A L SV EMTLDAD G GEILDY - EF Y R S VI R S KARLT YE EVDA I LE -------------------------- 133
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 719 vlwlhdiassirktrldngaltinnakl RFL LD P i T G EPLSFEVEKQRE A NR L I EEFM L LAN Q AVARF IHDSFPD i AVL R 798
Cdd:smart00955 134 ---------------------------- KIV LD E - E G KIEDIVPRERND A HS L V EEFM I LAN E AVARF LAKNGIP - GLY R 183
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 799 N H PP P - LI K SLKA L R E K L LA LG FE L - DYSSS KAL QESMVRLCNEAPNPV amnac L SQ LL MKP M AR A T Y FCSEGK sepadl 876
Cdd:smart00955 184 V H EG P d PE K LAEL L K E F L AL LG LL L l GGDGP KAL AKLLEKIRDSPEERL ----- L EL LL LRS M PH A E Y SVDNSG ------ 252
330 340 350
....*....|....*....|....*....|....
gi 24654592 877 w H YA L SIPI YTHFTSPIRRYPD IL VHR L L A AAL K 910
Cdd:smart00955 253 - H FG L ALDA YTHFTSPIRRYPD LI VHR Q L K AAL R 285
RNase_R
TIGR02063 ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. ...
420-957
3.09e-82
ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA]
Pssm-ID: 273947 [Multi-domain]
Cd Length: 709
Bit Score: 282.24
E-value: 3.09e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 420 PK A F VI A I TK R T e LR QIVGT ISFT N PTKLC --- D DQLFYKF rpydlrvpmv YV P KDACA - A HI G N K qqidvsgll Y L AH I 495
Cdd:TIGR02063 123 FE A R VI K I LE R A - ND QIVGT FYIE N GIGFV ipd D KRIYLDI ---------- FI P PEQIL g A EE G D K --------- V L VE I 182
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 496 LE - T D C N GHC I AELIQ pvg RV G NL DD --- ELKA I LFHN G L rd IKP F EQRFI D IYSQP P PPISQ E DLRQ RKDLR KMCIF TI 571
Cdd:TIGR02063 183 TK y P D R N RPA I GKVVE --- IL G HA DD pgi DILI I IRKH G I -- PYE F PEEVL D EAAKI P EEVPE E EIKG RKDLR DLPFV TI 257
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 572 D PMT A R D L DDAV SI EKL G D NE Y EI GV H I S DVSH FLI E DNE LD NIVKE R S TS I YL ANE VI H MLP QS L CMR - CSL L P GQ D KF 650
Cdd:TIGR02063 258 D GED A K D F DDAV YV EKL K D GN Y KL GV A I A DVSH YVR E GSA LD KEALK R G TS V YL PDR VI P MLP ER L SNG i CSL N P NE D RL 337
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 651 AF S VFWRMNG KG VM lq KK P EF CRT VINS CSQFA Y EHAQK II - DNPNERFT E NDFPTI L NG fnpddirnrvlw L HDIASSI 729
Cdd:TIGR02063 338 TL S CEMEIDK KG RV -- KK Y EF YEA VINS HARLT Y NQVND II e GKDALDKK E PPLKEM L KN ------------ L FELYKIL 403
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 730 RK T R LDN GA LTINNAKLRFL LD P i T G E P LSFEVEKQRE A NR LIEEFM LL AN QA VA RFIHDS - F P di AVL R N H PP P LIKS L 808
Cdd:TIGR02063 404 RK K R KKR GA IDFDSKEAKII LD E - N G K P IDIVPRERGD A HK LIEEFM IA AN ET VA EHLEKA k L P -- FIY R V H ER P SEEK L 480
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 809 KA LRE K L LA LG FE L DYSS S KAL Q ESMVR -- L CNEAPN P VAM na CLSQL L MKP M AR A T Y fcsegks E P ADLW H YA L SIPI Y 886
Cdd:TIGR02063 481 QN LRE F L KT LG IT L KGGT S DKP Q PKDFQ kl L EKVKGR P EEE -- LINTV L LRS M QQ A K Y ------- S P ENIG H FG L ALEY Y 551
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24654592 887 THFTSPIRRYPD IL VHRL LAA AL --- KYC T PP K RT --- PDD L HTLTKLANERKYN A KK A GE D SGNLYFKR Y VHN K Q G 957
Cdd:TIGR02063 552 THFTSPIRRYPD LI VHRL IKK AL fgg ENT T TE K ER eyl EAK L EEIAEHSSKTERR A DE A ER D VNDWKKAE Y MSE K I G 628
PRK05054
PRK05054 exoribonuclease II; Provisional
560-985
7.85e-38
exoribonuclease II; Provisional
Pssm-ID: 179920 [Multi-domain]
Cd Length: 644
Bit Score: 151.57
E-value: 7.85e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 560 R K DL RKMCIF TID PMTAR D L DDA VSI EKL G D NEYEIG V H I S D VSHFLI E DNE LD NIVKE R STSI YL ANEV I H MLP QS L C - 638
Cdd:PRK05054 190 R E DL TALDFV TID SASTE D M DDA LYV EKL P D GGLQLT V A I A D PTAYIA E GSK LD KAARQ R AFTN YL PGFN I P MLP RE L S d 269
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 639 MR CSL L P GQDKF A FSVFWRMNGK G V m LQKKPE F CRTV I N S CSQF AY EHAQKIID N PNERFT E N dfptilngfnp DD I RNR 718
Cdd:PRK05054 270 DL CSL R P NERRP A LACRVTIDAD G T - IEDDIR F FAAW I E S KAKL AY DNVSDWLE N GGDWQP E S ----------- EA I AEQ 337
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 719 VLW LH DIASSIRKT R LDNGALTINNAKL RF L L DP i T GE P L SFEV E KQ R E ANR LI EE F M LL AN QAV AR FIH D SF ------- 791
Cdd:PRK05054 338 IRL LH QFCLARSEW R KQHALVFKDRPDY RF E L GE - K GE V L DIVA E PR R I ANR IV EE S M IA AN ICA AR VLR D KL gfgiynv 416
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 792 ----- P D ----- I A V L RN H ppplik S L KALR E K LL A L - GF ----- ELD YSSSKA L q E S MV R lcneapnpvamnaclsqll 855
Cdd:PRK05054 417 hsgfd P A naeqa V A L L KE H ------ G L HFDA E E LL T L e GF cklrr ELD AQPTGY L - D S RI R ------------------- 470
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 856 mkpma R ATY F c S E GKS EP AD lw H YA L SIPI Y THF TSPIR R Y P D ILV HRLL A A AL K YC T PPK rt P D D l HTLTK LA NE R KY N 935
Cdd:PRK05054 471 ----- R FQS F - A E IST EP GP -- H FG L GLEA Y ATW TSPIR K Y G D MIN HRLL K A VI K GE T AER -- P Q D - EITVQ LA ER R RL N 539
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 24654592 936 a KK A GE D S G N - LY F k RY VHN K Q G IYM R -- A VV I E I FQHM M N V VT LE S G H V IS I 985
Cdd:PRK05054 540 - RM A ER D V G D w LY A - RY LKD K A G TDT R fa A EI I D I SRGG M R V RL LE N G A V AF I 590
OB_Dis3
pfam17849 Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 ...
454-530
8.28e-10
Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 protein. This domain along with CSD1 binds to RNA.
Pssm-ID: 436091 [Multi-domain]
Cd Length: 77
Bit Score: 56.08
E-value: 8.28e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24654592 454 FYK F R P Y D L R V P MVYV P KDACAAHIGNKQQ i D VS G L L YLAH I LETDC N - GHCIAELIQPV G RV G NLDD E LK AIL FH NG 530
Cdd:pfam17849 1 YVL F V P R D K R I P RIRI P TKSAPEEFLENPE - D LE G K L FVVK I DDWPE N s RYPLGHIVKVL G EI G DIET E TE AIL LE NG 77
Name
Accession
Description
Interval
E-value
RNB
pfam00773 RNB domain; This domain is the catalytic domain of ribonuclease II.
560-909
1.75e-97
RNB domain; This domain is the catalytic domain of ribonuclease II.
Pssm-ID: 459934 [Multi-domain]
Cd Length: 314
Bit Score: 310.76
E-value: 1.75e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 560 RKDLR KMCIF TIDP MT A R DLDDA V S I EKL GDNE Y EI GVHI S DVSH FLIEDNE LD NIVKE R S TS I YL ANE VI H MLP QS L CM 639
Cdd:pfam00773 1 RKDLR DLPFI TIDP AD A K DLDDA I S V EKL PNGG Y RL GVHI A DVSH YVPPGSP LD REARK R G TS V YL PDR VI P MLP EK L SN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 640 R - CSL L PG Q D KF A F SV FWRMNGK G VM lq KKP E FCRT VI N S CSQFA YE HAQKIIDNPNE rftendfptiln GFNPD D IRNR 718
Cdd:pfam00773 81 D l CSL N PG E D RL A L SV EITIDAD G EV -- TSY E IYPS VI R S KARLT YE EVDDLLEGKDA ------------ EKDKP D LAED 146
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 719 VLW L HDI A SSI R KT RL DN GAL TINNAKLRFL LD P it GEPLSFEVEKQRE A NR LIEEFMLLAN Q AVAR FIHD s FPDI A VL R 798
Cdd:pfam00773 147 LRL L YEL A KIL R AK RL QR GAL DLDTPENKLI LD E -- EGVIDILIQERTD A HS LIEEFMLLAN E AVAR HLQE - LGIP A LY R 223
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 799 N HP P P LIKS L KA L REK L LA L GFELDY S S S KALQESMV RL cneapnpvamnac LS Q LL MKP M A RA T Y F csegkse P AD L W H 878
Cdd:pfam00773 224 V HP E P DLEK L NS L IKL L QL L PDDKGL S K S LEKIKDDE RL ------------- LS I LL LRT M P RA E Y S ------- P EP L G H 283
330 340 350
....*....|....*....|....*....|.
gi 24654592 879 YA L SIP IYTHFTSPIRRYPD IL VHR L L A A A L 909
Cdd:pfam00773 284 FG L GLD IYTHFTSPIRRYPD LI VHR Q L K A L L 314
VacB
COG0557 Exoribonuclease R [Transcription];
420-929
9.43e-95
Exoribonuclease R [Transcription];
Pssm-ID: 440323 [Multi-domain]
Cd Length: 711
Bit Score: 316.66
E-value: 9.43e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 420 P KAF V IA I TK R T e LRQI VG TISFTNP tklcddql F YKFR P Y D L R VPM - VYV P K D ACA - A HI G NK qqid V sglly LAH I LE 497
Cdd:COG0557 122 P EGR V VE I LE R A - NTRV VG RFEKEKG -------- F GFVV P D D K R LLQ d IFI P P D DLN g A KD G DL ---- V ----- VVE I TR 183
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 498 TDCNGH ciaeli Q P V GRV ---- G NLD D --- E LKAILFHN GL RDI kp F EQRFIDIYSQP P PPISQE DL RQ R K DLR KMCIF T 570
Cdd:COG0557 184 YPERRG ------ P P E GRV vevl G SPG D pga E ILIAIRKH GL PHE -- F PEEVLAEAEAL P DEVPEA DL KG R R DLR DLPLV T 255
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 571 ID PMT A R D L DDAVS I EKL GDNEYEI GVHI S DVSH FLIEDNE LD NIVKE R S TS I YL ANE VI H MLP QS L C - MR CSL L PG Q D K 649
Cdd:COG0557 256 ID GED A K D F DDAVS A EKL DNGGWRL GVHI A DVSH YVRPGSA LD REARK R G TS V YL PDR VI P MLP ER L S n GL CSL N PG E D R 335
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 650 F A F S VFWRMNG KG VM lq KKP EF C R T VI N S CSQFA YE HA Q K I I D NPN E RFT E ND fptilngfnp D D IRNRVLW L HDI A SSI 729
Cdd:COG0557 336 L A M S CEMEIDA KG EV -- VSY EF Y R S VI R S DARLT YE EV Q A I L D GKD E ELR E EY ---------- A D LVPMLEE L YEL A KIL 403
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 730 RK T R LDN GA LTINNAKLRFL LD P i T G E P LSFEVEKQRE A NR LIEEFMLLAN Q AVA R F IHDS fp DIAV L - R N H PP P LIKS L 808
Cdd:COG0557 404 RK A R EKR GA IDFDLPETKII LD E - E G K P EDIVPRERND A HK LIEEFMLLAN E AVA E F LEKL -- KLPF L y R V H EE P DPEK L 480
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 809 K ALRE K L LA LG FE L --- D YSSS K A LQ esmv R L CNEAPNPVAMNA c L SQ LL MKP M AR A T Y fcsegks E P ADLW H YA L SIPI 885
Cdd:COG0557 481 E ALRE F L AN LG LK L kgg D EPTP K D LQ ---- K L LEQVKGRPEEEL - L NT LL LRS M KQ A V Y ------- S P ENIG H FG L ALEA 548
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 24654592 886 YTHFTSPIRRYPD I LVHR L L A A A L KYCTP P KRTPDDLHT L TKL A 929
Cdd:COG0557 549 YTHFTSPIRRYPD L LVHR A L K A Y L EGKRS P GLQEYLEEE L EEI A 592
RNB
smart00955 This domain is the catalytic domain of ribonuclease II;
560-910
2.28e-92
This domain is the catalytic domain of ribonuclease II;
Pssm-ID: 214935 [Multi-domain]
Cd Length: 286
Bit Score: 296.10
E-value: 2.28e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 560 R K DLR KMCI FTIDP MT A R D L DDAVS I EKL GDNE Y EI GVHI S DVSH FLIEDNE LD NIVKE R S TS I YL ANE VI H MLP QS L CM 639
Cdd:smart00955 1 R V DLR DLPL FTIDP ED A K D I DDAVS V EKL DNGG Y RL GVHI A DVSH YVKPGSA LD REARK R G TS V YL PDR VI P MLP EE L SN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 640 - R CSL L PG Q D KF A F SV FWRMNGK G VMLQKK p EF C R T VI N S CSQFA YE HAQK I ID npnerftendfptilngfnpddirnr 718
Cdd:smart00955 81 g L CSL N PG E D RL A L SV EMTLDAD G GEILDY - EF Y R S VI R S KARLT YE EVDA I LE -------------------------- 133
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 719 vlwlhdiassirktrldngaltinnakl RFL LD P i T G EPLSFEVEKQRE A NR L I EEFM L LAN Q AVARF IHDSFPD i AVL R 798
Cdd:smart00955 134 ---------------------------- KIV LD E - E G KIEDIVPRERND A HS L V EEFM I LAN E AVARF LAKNGIP - GLY R 183
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 799 N H PP P - LI K SLKA L R E K L LA LG FE L - DYSSS KAL QESMVRLCNEAPNPV amnac L SQ LL MKP M AR A T Y FCSEGK sepadl 876
Cdd:smart00955 184 V H EG P d PE K LAEL L K E F L AL LG LL L l GGDGP KAL AKLLEKIRDSPEERL ----- L EL LL LRS M PH A E Y SVDNSG ------ 252
330 340 350
....*....|....*....|....*....|....
gi 24654592 877 w H YA L SIPI YTHFTSPIRRYPD IL VHR L L A AAL K 910
Cdd:smart00955 253 - H FG L ALDA YTHFTSPIRRYPD LI VHR Q L K AAL R 285
RNase_R
TIGR02063 ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. ...
420-957
3.09e-82
ribonuclease R; This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA]
Pssm-ID: 273947 [Multi-domain]
Cd Length: 709
Bit Score: 282.24
E-value: 3.09e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 420 PK A F VI A I TK R T e LR QIVGT ISFT N PTKLC --- D DQLFYKF rpydlrvpmv YV P KDACA - A HI G N K qqidvsgll Y L AH I 495
Cdd:TIGR02063 123 FE A R VI K I LE R A - ND QIVGT FYIE N GIGFV ipd D KRIYLDI ---------- FI P PEQIL g A EE G D K --------- V L VE I 182
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 496 LE - T D C N GHC I AELIQ pvg RV G NL DD --- ELKA I LFHN G L rd IKP F EQRFI D IYSQP P PPISQ E DLRQ RKDLR KMCIF TI 571
Cdd:TIGR02063 183 TK y P D R N RPA I GKVVE --- IL G HA DD pgi DILI I IRKH G I -- PYE F PEEVL D EAAKI P EEVPE E EIKG RKDLR DLPFV TI 257
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 572 D PMT A R D L DDAV SI EKL G D NE Y EI GV H I S DVSH FLI E DNE LD NIVKE R S TS I YL ANE VI H MLP QS L CMR - CSL L P GQ D KF 650
Cdd:TIGR02063 258 D GED A K D F DDAV YV EKL K D GN Y KL GV A I A DVSH YVR E GSA LD KEALK R G TS V YL PDR VI P MLP ER L SNG i CSL N P NE D RL 337
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 651 AF S VFWRMNG KG VM lq KK P EF CRT VINS CSQFA Y EHAQK II - DNPNERFT E NDFPTI L NG fnpddirnrvlw L HDIASSI 729
Cdd:TIGR02063 338 TL S CEMEIDK KG RV -- KK Y EF YEA VINS HARLT Y NQVND II e GKDALDKK E PPLKEM L KN ------------ L FELYKIL 403
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 730 RK T R LDN GA LTINNAKLRFL LD P i T G E P LSFEVEKQRE A NR LIEEFM LL AN QA VA RFIHDS - F P di AVL R N H PP P LIKS L 808
Cdd:TIGR02063 404 RK K R KKR GA IDFDSKEAKII LD E - N G K P IDIVPRERGD A HK LIEEFM IA AN ET VA EHLEKA k L P -- FIY R V H ER P SEEK L 480
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 809 KA LRE K L LA LG FE L DYSS S KAL Q ESMVR -- L CNEAPN P VAM na CLSQL L MKP M AR A T Y fcsegks E P ADLW H YA L SIPI Y 886
Cdd:TIGR02063 481 QN LRE F L KT LG IT L KGGT S DKP Q PKDFQ kl L EKVKGR P EEE -- LINTV L LRS M QQ A K Y ------- S P ENIG H FG L ALEY Y 551
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24654592 887 THFTSPIRRYPD IL VHRL LAA AL --- KYC T PP K RT --- PDD L HTLTKLANERKYN A KK A GE D SGNLYFKR Y VHN K Q G 957
Cdd:TIGR02063 552 THFTSPIRRYPD LI VHRL IKK AL fgg ENT T TE K ER eyl EAK L EEIAEHSSKTERR A DE A ER D VNDWKKAE Y MSE K I G 628
3_prime_RNase
TIGR00358 VacB and RNase II family 3'-5' exoribonucleases; This model is defined to identify a pair of ...
422-967
2.06e-59
VacB and RNase II family 3'-5' exoribonucleases; This model is defined to identify a pair of paralogous 3-prime exoribonucleases in E. coli, plus the set of proteins apparently orthologous to one or the other in other eubacteria. VacB was characterized originally as required for the expression of virulence genes, but is now recognized as the exoribonuclease RNase R (Rnr). Its paralog in E. coli and H. influenzae is designated exoribonuclease II (Rnb). Both are involved in the degradation of mRNA, and consequently have strong pleiotropic effects that may be difficult to disentangle. Both these proteins share domain-level similarity (RNB, S1) with a considerable number of other proteins, and full-length similarity scoring below the trusted cutoff to proteins associated with various phenotypes but uncertain biochemistry; it may be that these latter proteins are also 3-prime exoribonucleases. [Transcription, Degradation of RNA]
Pssm-ID: 273033 [Multi-domain]
Cd Length: 654
Bit Score: 216.12
E-value: 2.06e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 422 A F V IA I TKRT e L RQI VG TISFT N PTK -- LC DD QLF Y K frpy D LR VP MVY V PKDA caahignkqqid VS G LLYLAHIL E TD 499
Cdd:TIGR00358 72 A E V ER I LEPA - L TRF VG KFLGE N DFG fv VP DD PRI Y L ---- D II VP KAS V KNEL ------------ AE G DKVVVELT E YP 134
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 500 C - NGHCIA E LI Q pvg RV GN L DD E L --- KAI L FHNGL rdik PFE qr F I D IYS Q P ---- PPPISQEDLRQ R K DL RKMCIF TI 571
Cdd:TIGR00358 135 L r RNLFYG E IT Q --- IL GN N DD P L ipw WVT L ARHEI ---- PFE -- F P D GVE Q Q aakl QFDVDEQAKKY R E DL TDLAFV TI 205
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 572 D PMT A R DLDDAV SIE KL G D NEYEIG V H I S DVS HFLI E DNE LD NIV K E R ST S I YL ANE VI H MLP QS L CMR - CSL L P GQ D KF 650
Cdd:TIGR00358 206 D GAD A K DLDDAV YVK KL P D GGWKLY V A I A DVS YYVA E NSP LD KEA K H R GF S V YL PGF VI P MLP EE L SNG l CSL N P NE D RL 285
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 651 AFSVFWRMNGK G VMLQK kp EF CRTV I N S CSQFA Y EHAQKIID N PN E RFT E nd FP T ILNGFN pddirnrvl W LH DIASSIR 730
Cdd:TIGR00358 286 VLVCEMTISAQ G RITDN -- EF YPAT I E S KARLT Y DKVNDWLE N DD E LQP E -- YE T LVEQLK --------- A LH QLSQALG 352
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 731 KT R LDN G ALTINNAKLR F LL D P i T G EPLSFEV E KQ R E A NRL IEE F M LL AN QAV ARF I H DS f PDIAVL R N HP P P LI K S L KA 810
Cdd:TIGR00358 353 EW R HKR G LIDFEHPETK F IV D E - E G RVIDIVA E VR R I A EKI IEE A M IV AN ICA ARF L H NH - KVPGIY R V HP G P SK K K L QS 430
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 811 L R E K L LA LG ----- FELDYSSSKALQESMVR lcn EAPN P VA mn AC L SQL L MKPMAR A T Y fcseg KS EP ad L W H YA L SIPI 885
Cdd:TIGR00358 431 L L E F L AE LG ltlpg GNAENVTTLDGACWLRE --- VKDR P EY -- EI L VTR L LRSLSQ A E Y ----- SP EP -- L G H FG L GLEH 498
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 886 Y T HFTSPIRRYPD ILV HRL LA A A L KYCTPPKRTPDDLHT L TKL A NERKYNAKK A GE --- D SGNLYFK RY VHN K Q G IYMRA 962
Cdd:TIGR00358 499 Y A HFTSPIRRYPD LTN HRL IK A V L AKEQTDTERYQPQDE L LQI A EHCSDTERR A RD aer D VADWLKC RY LLD K V G TEFSG 578
....*
gi 24654592 963 VVIEI 967
Cdd:TIGR00358 579 EISSV 583
PRK05054
PRK05054 exoribonuclease II; Provisional
560-985
7.85e-38
exoribonuclease II; Provisional
Pssm-ID: 179920 [Multi-domain]
Cd Length: 644
Bit Score: 151.57
E-value: 7.85e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 560 R K DL RKMCIF TID PMTAR D L DDA VSI EKL G D NEYEIG V H I S D VSHFLI E DNE LD NIVKE R STSI YL ANEV I H MLP QS L C - 638
Cdd:PRK05054 190 R E DL TALDFV TID SASTE D M DDA LYV EKL P D GGLQLT V A I A D PTAYIA E GSK LD KAARQ R AFTN YL PGFN I P MLP RE L S d 269
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 639 MR CSL L P GQDKF A FSVFWRMNGK G V m LQKKPE F CRTV I N S CSQF AY EHAQKIID N PNERFT E N dfptilngfnp DD I RNR 718
Cdd:PRK05054 270 DL CSL R P NERRP A LACRVTIDAD G T - IEDDIR F FAAW I E S KAKL AY DNVSDWLE N GGDWQP E S ----------- EA I AEQ 337
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 719 VLW LH DIASSIRKT R LDNGALTINNAKL RF L L DP i T GE P L SFEV E KQ R E ANR LI EE F M LL AN QAV AR FIH D SF ------- 791
Cdd:PRK05054 338 IRL LH QFCLARSEW R KQHALVFKDRPDY RF E L GE - K GE V L DIVA E PR R I ANR IV EE S M IA AN ICA AR VLR D KL gfgiynv 416
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 792 ----- P D ----- I A V L RN H ppplik S L KALR E K LL A L - GF ----- ELD YSSSKA L q E S MV R lcneapnpvamnaclsqll 855
Cdd:PRK05054 417 hsgfd P A naeqa V A L L KE H ------ G L HFDA E E LL T L e GF cklrr ELD AQPTGY L - D S RI R ------------------- 470
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 856 mkpma R ATY F c S E GKS EP AD lw H YA L SIPI Y THF TSPIR R Y P D ILV HRLL A A AL K YC T PPK rt P D D l HTLTK LA NE R KY N 935
Cdd:PRK05054 471 ----- R FQS F - A E IST EP GP -- H FG L GLEA Y ATW TSPIR K Y G D MIN HRLL K A VI K GE T AER -- P Q D - EITVQ LA ER R RL N 539
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 24654592 936 a KK A GE D S G N - LY F k RY VHN K Q G IYM R -- A VV I E I FQHM M N V VT LE S G H V IS I 985
Cdd:PRK05054 540 - RM A ER D V G D w LY A - RY LKD K A G TDT R fa A EI I D I SRGG M R V RL LE N G A V AF I 590
Rnb
COG4776 Exoribonuclease II [Transcription];
554-985
9.46e-37
Exoribonuclease II [Transcription];
Pssm-ID: 443808 [Multi-domain]
Cd Length: 644
Bit Score: 148.08
E-value: 9.46e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 554 QEDLRQ R K DL RKMCIF TID PMTAR D L DDA VS IEKL GDNEYEIG V H I S D VSHFLI E DN ELD NIVKE R STSI YL ANEV I H ML 633
Cdd:COG4776 184 LDEGLE R E DL TALPFV TID SESTE D M DDA LY IEKL ENGGWKLT V A I A D PTAYIP E GS ELD KEARQ R AFTN YL PGFN I P ML 263
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 634 P QS L C - MR CSL LPGQDKF A F -- S V FWRMN G K gvm LQKKP EF CRTV I N S CSQF AY EHAQKIIDNPN E RFT EN D fptilngf 710
Cdd:COG4776 264 P RE L S d DL CSL KENEKRP A L vc R V TIDAD G S --- IGDDI EF FAAW I R S KAKL AY DNVSDWLEGKG E WQP EN E -------- 332
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 711 npd D I RNRVLW LH DI A SSIRKT R LDNGALTINNAKL RF L LD P i T G EP L SFEV E KQ R E ANR LI EE F M LL AN QAV AR F ---- 786
Cdd:COG4776 333 --- E I AEQIRL LH QF A LARSQW R QQHALVFKDRPDY RF E LD E - K G NV L DIHA E PR R I ANR IV EE A M IA AN ICA AR V lreh 408
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 787 ------- I H DS F PD ------ IAV L RN H PPPLIK slkalr E K LL A L - GF ----- ELD YSSSKA L q E S MV R LCN eapnpvam 847
Cdd:COG4776 409 lgfgifn V H SG F DP ekleqa VEL L AE H GIEFDP ------ E Q LL T L e GF calrr ELD AQPTSY L - D S RL R RFQ -------- 473
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 848 naclsqllmkpmara T Y fc S E GKS EP AD lw H YA L SIPI Y THF TSPIR R Y P D ILV HRL LA A ALKY c T P PKRTPDD L ht LTK 927
Cdd:COG4776 474 --------------- T F -- A E IST EP GP -- H FG L GLDA Y ATW TSPIR K Y G D MVN HRL IK A VILG - Q P AEKPDEE L -- TER 531
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 928 LA NE R KY N a KK A GE D SGNLYFK RY VHN K -- Q G IYMR A VV I E I FQHMMN V VT LE S G H V IS I 985
Cdd:COG4776 532 LA ER R RL N - RM A ER D VADWLYA RY LKP K vg S G QVFT A EI I D I NRGGLR V RL LE N G A V AF I 590
PRK11642
PRK11642 ribonuclease R;
560-911
3.54e-33
ribonuclease R;
Pssm-ID: 236944 [Multi-domain]
Cd Length: 813
Bit Score: 138.34
E-value: 3.54e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 560 R K DLR KMCIF TID PMT ARD L DDAV SI EK LGDNEYEIG V H I S DVS HFLIEDNE LD NIVKE R S TS I Y LANE V IH MLP QS L CM 639
Cdd:PRK11642 260 R V DLR DLPLV TID GED ARD F DDAV YC EK KRGGGWRLW V A I A DVS YYVRPPTP LD REARN R G TS V Y FPSQ V VP MLP EV L SN 339
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 640 - R CSL L P GQ D KFAFSVFWRMNG KG VMLQK K pe F CRT V IN S CSQFA Y EHAQK I IDN p NERFT E NDF P TI lngfnpddir NR 718
Cdd:PRK11642 340 g L CSL N P QV D RLCMVCEMTISS KG RLTGY K -- F YEA V MS S HARLT Y TKVWH I LQG - DQDLR E QYA P LV ---------- KH 406
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 719 VLW LH DIASSIR K T R LDN G ALTINNAKLR F L ldpitgepls F EV E KQR E --------- A NR LIEE F M L LAN QAV ARF IHD 789
Cdd:PRK11642 407 LEE LH NLYKVLD K A R EER G GISFESEEAK F I ---------- F NA E RRI E rieqtqrnd A HK LIEE C M I LAN ISA ARF VEK 476
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24654592 790 S f PDI A VL R N H PP P LIKSLKAL R EK L LA LG F EL DYSSSKALQESMVR L CNE A PN P V A mn AC L SQL L MKP M AR A T Y fcseg 869
Cdd:PRK11642 477 A - KEP A LF R I H DK P STEAITSF R SV L AE LG L EL PGGNKPEPRDYAEL L ESV A DR P D A -- EM L QTM L LRS M KQ A I Y ----- 548
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 24654592 870 ks E P ADLW H YA L SIPI Y T HFTSPIRRYPD ILV HR llaa A L KY 911
Cdd:PRK11642 549 -- D P ENRG H FG L ALQS Y A HFTSPIRRYPD LSL HR ---- A I KY 584
OB_Dis3
pfam17849 Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 ...
454-530
8.28e-10
Dis3-like cold-shock domain 2 (CSD2); This domain has an OB fold and is found in the Dis3l2 protein. This domain along with CSD1 binds to RNA.
Pssm-ID: 436091 [Multi-domain]
Cd Length: 77
Bit Score: 56.08
E-value: 8.28e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24654592 454 FYK F R P Y D L R V P MVYV P KDACAAHIGNKQQ i D VS G L L YLAH I LETDC N - GHCIAELIQPV G RV G NLDD E LK AIL FH NG 530
Cdd:pfam17849 1 YVL F V P R D K R I P RIRI P TKSAPEEFLENPE - D LE G K L FVVK I DDWPE N s RYPLGHIVKVL G EI G DIET E TE AIL LE NG 77
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
