|
Name |
Accession |
Description |
Interval |
E-value |
| AMPD |
cd01319 |
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at ... |
135-631 |
0e+00 |
|
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway.
Pssm-ID: 238644 Cd Length: 496 Bit Score: 930.62 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 135 FVNDMQVMCNMIADGPLKSFCYRRLCYLSSKYQMHVLLNELRELAAQKAVPHRDFYNTRKVDTHIHAASCMNQKHLLRFI 214
Cdd:cd01319 1 FYLDLEFLLALISDGPAKSFCYRRLQYLESKFQLHVLLNEDRELKEQKTVPHRDFYNVRKVDTHVHHSACMNQKHLLRFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 215 KKTLKNNANEVVTVTNGQQMTLAQVFQSMNLTTYDLTVDMLDVHADRNTFHRFDKFNSKYNPIGESRLREVFLKTDNYLN 294
Cdd:cd01319 81 KKKLRTEPDEVVIFRDGKKLTLKEVFDSLKLTAYDLSVDTLDVHADRNTFHRFDKFNLKYNPIGESRLREIFLKTDNYIN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 295 GKYFAQIIKEVAFDLEESKYQNAELRLSIYGKSPDEWYKLAKWAIDNDVYSSNIRWLIQIPRLFDIFKSNKMMKSFQEIL 374
Cdd:cd01319 161 GRYLAEITKEVFSDLEESKYQHAEYRLSIYGRSKDEWDKLASWVVDNDLFSPNVRWLIQIPRLYDVYKKSGIVNSFQEML 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 375 NNIFLPLFEATARPSKHPELHRFLQYVIGFDSVDDESKPEnPLFDNDVPRPEEWTYEENPPYAYYIYYMYANMTVLNKFR 454
Cdd:cd01319 241 ENIFEPLFEATKDPSSHPELHVFLQQVIGFDSVDDESKSE-RRFTRKFPKPEEWTSEENPPYSYYLYYMYANITTLNSFR 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 455 QSRNMNTFVLRPHCGEAGPVQHLVCGFLMAENISHGLLLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLNYHRNPLPEYLA 534
Cdd:cd01319 320 KARGFNTFVLRPHCGEAGDIDHLASAFLLAHGISHGINLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLSYEKNPFPEFFK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 535 RGLIISLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSSCDMCELARNSVMMSGFPHAIKQQWLGPIYYEDGIMGNDITRTN 614
Cdd:cd01319 400 RGLNVSLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSTCDMCELARNSVLQSGFEHSIKRHWLGPNYLKRGVAGNDIRRTN 479
|
490
....*....|....*..
gi 281360851 615 VPEIRVAYRYETLLDEL 631
Cdd:cd01319 480 VPQIRMAYRYETLCEEL 496
|
|
| AMP_deaminase |
pfam19326 |
AMP deaminase; |
10-634 |
0e+00 |
|
AMP deaminase;
Pssm-ID: 437158 [Multi-domain] Cd Length: 622 Bit Score: 893.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 10 FQRVSISGEDTSGVPLEDLERASTLLIEALRLRSHYMamsdqsFPSTTARFLKTVklkdrINNLPVKEVSDVHLRHSPMK 89
Cdd:pfam19326 3 VQRVTISGDYKLGVPTEDLEEAYKSLAECLEIREKYM------FPETTAPYLKSV-----QGEDSTPKENDEPVFHPPPK 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 90 ITNP--WNVEFPNDEDFKIKPLNGVFHIYENDDESsEIKYEYPDMSQFVNDMQVMCNMIADGPLKSFCYRRLCYLSSKYQ 167
Cdd:pfam19326 72 KGEDpyELFNFPPDLGYHLRMQDGVVHVYANKDAL-EDSLPYPDLRDFYTDLEHLLALIADGPIKTFCHRRLQYLESKFN 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 168 MHVLLNELRELAAQKAVPHRDFYNTRKVDTHIHAASCMNQKHLLRFIKKTLKNNANEVVTVTNGQQMTLAQVFQSMNLTT 247
Cdd:pfam19326 151 LHLMLNEMKELKAQKSNPHRDFYNVRKVDTHVHHSACMNQKHLLRFIKSKLRKEPDEVVIFRDGKYLTLREVFESLKLTG 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 248 YDLTVDMLDVHADRNTFHRFDKFNSKYNPIGESRLREVFLKTDNYLNGKYFAQIIKEVAFDLEESKYQNAELRLSIYGKS 327
Cdd:pfam19326 231 YDLSVDTLDVHADRDTFHRFDKFNLKYNPIGESRLREIFLKTDNYINGRYLAEITKEVFSDLEESKYQMAEYRISIYGRS 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 328 PDEWYKLAKWAIDNDVYSSNIRWLIQIPRLFDIFKSNKMMKSFQEILNNIFLPLFEATARPSKHPELHRFLQYVIGFDSV 407
Cdd:pfam19326 311 PDEWDKLASWIVDNKVYSPNVRWLIQVPRLYDIYKKKGIVPSFQKMLENIFLPLFEATVNPQSHPELHVFLKRVIGFDSV 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 408 DDESKPENPLFdNDVPRPEEWTYEENPPYAYYIYYMYANMTVLNKFRQSRNMNTFVLRPHCGEAGPVQHLVCGFLMAENI 487
Cdd:pfam19326 391 DDESKPERRMF-RKSPKPALWTNEQNPPYSYYLYYMYANIAVLNSLRKERGFNTFVLRPHCGEAGDIDHLVSAFLLAHGI 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 488 SHGLLLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLNYHRNPLPEYLARGLIISLSTDDPLQFHFTKEPLMEEYSIAAQVW 567
Cdd:pfam19326 470 SHGILLRKSPVLQYLYYLAQIGIAMSPLSNNSLFLEYHKNPFPEFFKRGLNVSLSTDDPLQFHFTKEPLMEEYSIAAQVW 549
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 281360851 568 KLSSCDMCELARNSVMMSGFPHAIKQQWLGPIYYEDGIMGNDITRTNVPEIRVAYRYETLLDELSNI 634
Cdd:pfam19326 550 KLSACDMCELARNSVLQSGFSHQLKSHWLGKDYYKEGPEGNDIRRTNVPDIRVAYRYETLCQELALI 616
|
|
| AMP_deaminase |
TIGR01429 |
AMP deaminase; This model describes AMP deaminase, a large, well-conserved eukaryotic protein ... |
26-634 |
0e+00 |
|
AMP deaminase; This model describes AMP deaminase, a large, well-conserved eukaryotic protein involved in energy metabolism. Most members of the family have an additional, poorly alignable region of 150 amino acids or more N-terminal to the region included in the model.
Pssm-ID: 273618 [Multi-domain] Cd Length: 611 Bit Score: 842.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 26 EDLERASTLLIEALRLRSHYMAMSDQSFPSTTARFLKTVKLKDRINnlPVKEVSDVHLRHSPMKITNPWNVEFPNDE-DF 104
Cdd:TIGR01429 1 EDLAEAAKSLAKALMLREKYARLAYHRFPDTTAQYLSHQGYPESVP--LEEGLPDFHPPPDPQEDPYCLDDDAPPIElGY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 105 KIKPLNGVFHIYEND---DESSEIKYEYPDMSQFVNDMQVMCNMIADGPLKSFCYRRLCYLSSKYQMHVLLNELRELAAQ 181
Cdd:TIGR01429 79 LVRMHGGVLFVYDNDtmlERQEPHFLVPPTLETYYVDMEHLLALISDGPTKSFCFRRLQYLESKFNLHELLNEMSELKEQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 182 KAVPHRDFYNTRKVDTHIHAASCMNQKHLLRFIKKTLKNNANEVVTVTNGQQMTLAQVFQSMNLTTYDLTVDMLDVHADR 261
Cdd:TIGR01429 159 KSVPHRDFYNVRKVDTHIHAAASMNQKHLLRFIKHKLKTEPDETVIERDGKKLTLREVFDSLHLDPYDLSVDTLDVHADR 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 262 NTFHRFDKFNSKYNPIGESRLREVFLKTDNYLNGKYFAQIIKEVAFDLEESKYQNAELRLSIYGKSPDEWYKLAKWAIDN 341
Cdd:TIGR01429 239 NTFHRFDKFNLKYNPVGESRLREIFLKTDNYIGGKYFAELVKEVFTDLEDSKYQYAEPRLSIYGRSPKEWDSLARWIIDH 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 342 DVYSSNIRWLIQIPRLFDIFKSNKMMKSFQEILNNIFLPLFEATARPSKHPELHRFLQYVIGFDSVDDESKPENPLFDND 421
Cdd:TIGR01429 319 DVFSPNVRWLIQVPRLYDVYRSKKLVPNFGDMLENVFLPLFEVTKDPSSHPELHLFLQQVTGFDSVDDESKHEDHMFSRK 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 422 VPRPEEWTYEENPPYAYYIYYMYANMTVLNKFRQSRNMNTFVLRPHCGEAGPVQHLVCGFLMAENISHGLLLRKVPVLQY 501
Cdd:TIGR01429 399 FPSPDEWTSEQNPPYSYYLYYMYANIMVLNNFRRERGLNTFLLRPHCGEAGSVDHLVSAFLTSHGINHGILLRKVPVLQY 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 502 LYYLTQIGIAMSPLSNNSLFLNYHRNPLPEYLARGLIISLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSSCDMCELARNS 581
Cdd:TIGR01429 479 LYYLTQIPIAMSPLSNNSLFLEYSKNPLPEYLHKGLNVSLSTDDPLQFHYTKEALMEEYAIAAQVWKLSTCDMCELARNS 558
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|...
gi 281360851 582 VMMSGFPHAIKQQWLGPIYYEDGIMGNDITRTNVPEIRVAYRYETLLDELSNI 634
Cdd:TIGR01429 559 VLQSGFEHQVKQHWLGPNYYKEGPEGNDIRRTNVPDIRVAFRYETLCNELSLL 611
|
|
| PLN03055 |
PLN03055 |
AMP deaminase; Provisional |
99-635 |
0e+00 |
|
AMP deaminase; Provisional
Pssm-ID: 178613 Cd Length: 602 Bit Score: 720.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 99 PNDEDFKIKP----------LNGVFHIYENDDESSEIkYEYPDMSQFVNDMQVMCNMIADGPLKSFCYRRLCYLSSKYQM 168
Cdd:PLN03055 46 PNPDPFRYEPeppsqhvfrmVDGVMHVYAPDDAKEEL-FPVPDATTFFTDMHRILRIVSLGNVRTFCHHRLKLLEQKFSL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 169 HVLLNELRELAAQKAVPHRDFYNTRKVDTHIHAASCMNQKHLLRFIKKTLKNNANEVVTVTNGQQMTLAQVFQSMNLTTY 248
Cdd:PLN03055 125 HLMLNADREFLAQKSAPHRDFYNVRKVDTHVHHSSCMNQKHLLRFIKSKLRKEPDEVVIFRDGKYLTLREVFESLDLTGY 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 249 DLTVDMLDVHADRNTFHRFDKFNSKYNPIGESRLREVFLKTDNYLNGKYFAQIIKEVAFDLEESKYQNAELRLSIYGKSP 328
Cdd:PLN03055 205 DLNVDLLDVHADKNTFHRFDKFNLKYNPCGQSRLREIFLKQDNLIQGRFLAELTKEVFSDLEASKYQMAEYRISIYGRKQ 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 329 DEWYKLAKWAIDNDVYSSNIRWLIQIPRLFDIFKSNKMMKSFQEILNNIFLPLFEATARPSKHPELHRFLQYVIGFDSVD 408
Cdd:PLN03055 285 SEWDQLASWIVNNRLYSENVVWLIQLPRLYNVYKEMGIVQSFQQILDNIFKPLFEVTVDPSSHPQLHVFLKMVVGFDMVD 364
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 409 DESKPENPLFDNDVPrPEEWTYEENPPYAYYIYYMYANMTVLNKFRQSRNMNTFVLRPHCGEAGPVQHLVCGFLMAENIS 488
Cdd:PLN03055 365 DESKPERRPTKHMQT-PEQWDIPFNPAYSYWAYYVYANLYTLNKLRESKGLNTIKFRPHAGEAGDIDHLAAAFLLAHNIA 443
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 489 HGLLLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLNYHRNPLPEYLARGLIISLSTDDPLQFHFTKEPLMEEYSIAAQVWK 568
Cdd:PLN03055 444 HGNNLRKSPGLQYLYYLAQIGLAMSPLSNNSLFLDYHRNPFPMFFARGLNVSLSTDDPLQIHLTKEPLVEEYSIAAQVWK 523
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 281360851 569 LSSCDMCELARNSVMMSGFPHAIKQQWLGPIYYEDGIMGNDITRTNVPEIRVAYRYETLLDELSNIF 635
Cdd:PLN03055 524 LSSCDLCEIARNSVLQSGFPHASKKHWVGDNYWLRGPAGNDIHKTNVPHMRVEFRHEVWKEELQYVF 590
|
|
| Add |
COG1816 |
Adenosine deaminase [Nucleotide transport and metabolism]; Adenosine deaminase is part of the ... |
453-596 |
3.11e-16 |
|
Adenosine deaminase [Nucleotide transport and metabolism]; Adenosine deaminase is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 441421 Cd Length: 326 Bit Score: 80.13 E-value: 3.11e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 453 FRQSRNMNtFVLRPHCGEAGPVQHL-----VCGflmAENISHGL-------LLRkvpvlqylyYL--TQIGIAMSPLSNN 518
Cdd:COG1816 174 FARAREAG-LHLTAHAGEAGGPESIwealdLLG---AERIGHGVraiedpaLVA---------RLadRGIPLEVCPTSNV 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 519 SL--FLNYHRNPLPEYLARGLIISLSTDDPLQFHFTkepLMEEYSIAAQVWKLSSCDMCELARNSVMMSGFPHAIKQQWL 596
Cdd:COG1816 241 QLgvVPSLAEHPLRRLLDAGVRVTLNTDDPLYFGTT---LTDEYELAAEAFGLSDADLAQLARNAIEASFLPEEEKAALL 317
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| AMPD |
cd01319 |
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at ... |
135-631 |
0e+00 |
|
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway.
Pssm-ID: 238644 Cd Length: 496 Bit Score: 930.62 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 135 FVNDMQVMCNMIADGPLKSFCYRRLCYLSSKYQMHVLLNELRELAAQKAVPHRDFYNTRKVDTHIHAASCMNQKHLLRFI 214
Cdd:cd01319 1 FYLDLEFLLALISDGPAKSFCYRRLQYLESKFQLHVLLNEDRELKEQKTVPHRDFYNVRKVDTHVHHSACMNQKHLLRFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 215 KKTLKNNANEVVTVTNGQQMTLAQVFQSMNLTTYDLTVDMLDVHADRNTFHRFDKFNSKYNPIGESRLREVFLKTDNYLN 294
Cdd:cd01319 81 KKKLRTEPDEVVIFRDGKKLTLKEVFDSLKLTAYDLSVDTLDVHADRNTFHRFDKFNLKYNPIGESRLREIFLKTDNYIN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 295 GKYFAQIIKEVAFDLEESKYQNAELRLSIYGKSPDEWYKLAKWAIDNDVYSSNIRWLIQIPRLFDIFKSNKMMKSFQEIL 374
Cdd:cd01319 161 GRYLAEITKEVFSDLEESKYQHAEYRLSIYGRSKDEWDKLASWVVDNDLFSPNVRWLIQIPRLYDVYKKSGIVNSFQEML 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 375 NNIFLPLFEATARPSKHPELHRFLQYVIGFDSVDDESKPEnPLFDNDVPRPEEWTYEENPPYAYYIYYMYANMTVLNKFR 454
Cdd:cd01319 241 ENIFEPLFEATKDPSSHPELHVFLQQVIGFDSVDDESKSE-RRFTRKFPKPEEWTSEENPPYSYYLYYMYANITTLNSFR 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 455 QSRNMNTFVLRPHCGEAGPVQHLVCGFLMAENISHGLLLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLNYHRNPLPEYLA 534
Cdd:cd01319 320 KARGFNTFVLRPHCGEAGDIDHLASAFLLAHGISHGINLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLSYEKNPFPEFFK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 535 RGLIISLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSSCDMCELARNSVMMSGFPHAIKQQWLGPIYYEDGIMGNDITRTN 614
Cdd:cd01319 400 RGLNVSLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSTCDMCELARNSVLQSGFEHSIKRHWLGPNYLKRGVAGNDIRRTN 479
|
490
....*....|....*..
gi 281360851 615 VPEIRVAYRYETLLDEL 631
Cdd:cd01319 480 VPQIRMAYRYETLCEEL 496
|
|
| AMP_deaminase |
pfam19326 |
AMP deaminase; |
10-634 |
0e+00 |
|
AMP deaminase;
Pssm-ID: 437158 [Multi-domain] Cd Length: 622 Bit Score: 893.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 10 FQRVSISGEDTSGVPLEDLERASTLLIEALRLRSHYMamsdqsFPSTTARFLKTVklkdrINNLPVKEVSDVHLRHSPMK 89
Cdd:pfam19326 3 VQRVTISGDYKLGVPTEDLEEAYKSLAECLEIREKYM------FPETTAPYLKSV-----QGEDSTPKENDEPVFHPPPK 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 90 ITNP--WNVEFPNDEDFKIKPLNGVFHIYENDDESsEIKYEYPDMSQFVNDMQVMCNMIADGPLKSFCYRRLCYLSSKYQ 167
Cdd:pfam19326 72 KGEDpyELFNFPPDLGYHLRMQDGVVHVYANKDAL-EDSLPYPDLRDFYTDLEHLLALIADGPIKTFCHRRLQYLESKFN 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 168 MHVLLNELRELAAQKAVPHRDFYNTRKVDTHIHAASCMNQKHLLRFIKKTLKNNANEVVTVTNGQQMTLAQVFQSMNLTT 247
Cdd:pfam19326 151 LHLMLNEMKELKAQKSNPHRDFYNVRKVDTHVHHSACMNQKHLLRFIKSKLRKEPDEVVIFRDGKYLTLREVFESLKLTG 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 248 YDLTVDMLDVHADRNTFHRFDKFNSKYNPIGESRLREVFLKTDNYLNGKYFAQIIKEVAFDLEESKYQNAELRLSIYGKS 327
Cdd:pfam19326 231 YDLSVDTLDVHADRDTFHRFDKFNLKYNPIGESRLREIFLKTDNYINGRYLAEITKEVFSDLEESKYQMAEYRISIYGRS 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 328 PDEWYKLAKWAIDNDVYSSNIRWLIQIPRLFDIFKSNKMMKSFQEILNNIFLPLFEATARPSKHPELHRFLQYVIGFDSV 407
Cdd:pfam19326 311 PDEWDKLASWIVDNKVYSPNVRWLIQVPRLYDIYKKKGIVPSFQKMLENIFLPLFEATVNPQSHPELHVFLKRVIGFDSV 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 408 DDESKPENPLFdNDVPRPEEWTYEENPPYAYYIYYMYANMTVLNKFRQSRNMNTFVLRPHCGEAGPVQHLVCGFLMAENI 487
Cdd:pfam19326 391 DDESKPERRMF-RKSPKPALWTNEQNPPYSYYLYYMYANIAVLNSLRKERGFNTFVLRPHCGEAGDIDHLVSAFLLAHGI 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 488 SHGLLLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLNYHRNPLPEYLARGLIISLSTDDPLQFHFTKEPLMEEYSIAAQVW 567
Cdd:pfam19326 470 SHGILLRKSPVLQYLYYLAQIGIAMSPLSNNSLFLEYHKNPFPEFFKRGLNVSLSTDDPLQFHFTKEPLMEEYSIAAQVW 549
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 281360851 568 KLSSCDMCELARNSVMMSGFPHAIKQQWLGPIYYEDGIMGNDITRTNVPEIRVAYRYETLLDELSNI 634
Cdd:pfam19326 550 KLSACDMCELARNSVLQSGFSHQLKSHWLGKDYYKEGPEGNDIRRTNVPDIRVAYRYETLCQELALI 616
|
|
| AMP_deaminase |
TIGR01429 |
AMP deaminase; This model describes AMP deaminase, a large, well-conserved eukaryotic protein ... |
26-634 |
0e+00 |
|
AMP deaminase; This model describes AMP deaminase, a large, well-conserved eukaryotic protein involved in energy metabolism. Most members of the family have an additional, poorly alignable region of 150 amino acids or more N-terminal to the region included in the model.
Pssm-ID: 273618 [Multi-domain] Cd Length: 611 Bit Score: 842.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 26 EDLERASTLLIEALRLRSHYMAMSDQSFPSTTARFLKTVKLKDRINnlPVKEVSDVHLRHSPMKITNPWNVEFPNDE-DF 104
Cdd:TIGR01429 1 EDLAEAAKSLAKALMLREKYARLAYHRFPDTTAQYLSHQGYPESVP--LEEGLPDFHPPPDPQEDPYCLDDDAPPIElGY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 105 KIKPLNGVFHIYEND---DESSEIKYEYPDMSQFVNDMQVMCNMIADGPLKSFCYRRLCYLSSKYQMHVLLNELRELAAQ 181
Cdd:TIGR01429 79 LVRMHGGVLFVYDNDtmlERQEPHFLVPPTLETYYVDMEHLLALISDGPTKSFCFRRLQYLESKFNLHELLNEMSELKEQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 182 KAVPHRDFYNTRKVDTHIHAASCMNQKHLLRFIKKTLKNNANEVVTVTNGQQMTLAQVFQSMNLTTYDLTVDMLDVHADR 261
Cdd:TIGR01429 159 KSVPHRDFYNVRKVDTHIHAAASMNQKHLLRFIKHKLKTEPDETVIERDGKKLTLREVFDSLHLDPYDLSVDTLDVHADR 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 262 NTFHRFDKFNSKYNPIGESRLREVFLKTDNYLNGKYFAQIIKEVAFDLEESKYQNAELRLSIYGKSPDEWYKLAKWAIDN 341
Cdd:TIGR01429 239 NTFHRFDKFNLKYNPVGESRLREIFLKTDNYIGGKYFAELVKEVFTDLEDSKYQYAEPRLSIYGRSPKEWDSLARWIIDH 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 342 DVYSSNIRWLIQIPRLFDIFKSNKMMKSFQEILNNIFLPLFEATARPSKHPELHRFLQYVIGFDSVDDESKPENPLFDND 421
Cdd:TIGR01429 319 DVFSPNVRWLIQVPRLYDVYRSKKLVPNFGDMLENVFLPLFEVTKDPSSHPELHLFLQQVTGFDSVDDESKHEDHMFSRK 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 422 VPRPEEWTYEENPPYAYYIYYMYANMTVLNKFRQSRNMNTFVLRPHCGEAGPVQHLVCGFLMAENISHGLLLRKVPVLQY 501
Cdd:TIGR01429 399 FPSPDEWTSEQNPPYSYYLYYMYANIMVLNNFRRERGLNTFLLRPHCGEAGSVDHLVSAFLTSHGINHGILLRKVPVLQY 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 502 LYYLTQIGIAMSPLSNNSLFLNYHRNPLPEYLARGLIISLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSSCDMCELARNS 581
Cdd:TIGR01429 479 LYYLTQIPIAMSPLSNNSLFLEYSKNPLPEYLHKGLNVSLSTDDPLQFHYTKEALMEEYAIAAQVWKLSTCDMCELARNS 558
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|...
gi 281360851 582 VMMSGFPHAIKQQWLGPIYYEDGIMGNDITRTNVPEIRVAYRYETLLDELSNI 634
Cdd:TIGR01429 559 VLQSGFEHQVKQHWLGPNYYKEGPEGNDIRRTNVPDIRVAFRYETLCNELSLL 611
|
|
| PLN03055 |
PLN03055 |
AMP deaminase; Provisional |
99-635 |
0e+00 |
|
AMP deaminase; Provisional
Pssm-ID: 178613 Cd Length: 602 Bit Score: 720.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 99 PNDEDFKIKP----------LNGVFHIYENDDESSEIkYEYPDMSQFVNDMQVMCNMIADGPLKSFCYRRLCYLSSKYQM 168
Cdd:PLN03055 46 PNPDPFRYEPeppsqhvfrmVDGVMHVYAPDDAKEEL-FPVPDATTFFTDMHRILRIVSLGNVRTFCHHRLKLLEQKFSL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 169 HVLLNELRELAAQKAVPHRDFYNTRKVDTHIHAASCMNQKHLLRFIKKTLKNNANEVVTVTNGQQMTLAQVFQSMNLTTY 248
Cdd:PLN03055 125 HLMLNADREFLAQKSAPHRDFYNVRKVDTHVHHSSCMNQKHLLRFIKSKLRKEPDEVVIFRDGKYLTLREVFESLDLTGY 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 249 DLTVDMLDVHADRNTFHRFDKFNSKYNPIGESRLREVFLKTDNYLNGKYFAQIIKEVAFDLEESKYQNAELRLSIYGKSP 328
Cdd:PLN03055 205 DLNVDLLDVHADKNTFHRFDKFNLKYNPCGQSRLREIFLKQDNLIQGRFLAELTKEVFSDLEASKYQMAEYRISIYGRKQ 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 329 DEWYKLAKWAIDNDVYSSNIRWLIQIPRLFDIFKSNKMMKSFQEILNNIFLPLFEATARPSKHPELHRFLQYVIGFDSVD 408
Cdd:PLN03055 285 SEWDQLASWIVNNRLYSENVVWLIQLPRLYNVYKEMGIVQSFQQILDNIFKPLFEVTVDPSSHPQLHVFLKMVVGFDMVD 364
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 409 DESKPENPLFDNDVPrPEEWTYEENPPYAYYIYYMYANMTVLNKFRQSRNMNTFVLRPHCGEAGPVQHLVCGFLMAENIS 488
Cdd:PLN03055 365 DESKPERRPTKHMQT-PEQWDIPFNPAYSYWAYYVYANLYTLNKLRESKGLNTIKFRPHAGEAGDIDHLAAAFLLAHNIA 443
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 489 HGLLLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLNYHRNPLPEYLARGLIISLSTDDPLQFHFTKEPLMEEYSIAAQVWK 568
Cdd:PLN03055 444 HGNNLRKSPGLQYLYYLAQIGLAMSPLSNNSLFLDYHRNPFPMFFARGLNVSLSTDDPLQIHLTKEPLVEEYSIAAQVWK 523
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 281360851 569 LSSCDMCELARNSVMMSGFPHAIKQQWLGPIYYEDGIMGNDITRTNVPEIRVAYRYETLLDELSNIF 635
Cdd:PLN03055 524 LSSCDLCEIARNSVLQSGFPHASKKHWVGDNYWLRGPAGNDIHKTNVPHMRVEFRHEVWKEELQYVF 590
|
|
| PLN02768 |
PLN02768 |
AMP deaminase |
9-635 |
0e+00 |
|
AMP deaminase
Pssm-ID: 215411 Cd Length: 835 Bit Score: 707.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 9 NFQRVSISGEDtsgVPLEDLERASTLLIEALRLRSHYMamsdqsFPSTTARFLKTVklkdrinnlpvkeVSDvhlRHSPM 88
Cdd:PLN02768 224 TFVRLNITPLE---VPSPDEVEAYKVLQECLELRKRYV------FREEVAPWEKEI-------------ISD---PSTPK 278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 89 KITNPWNVEFPNDEDFKIKPLNGVFHIYENDDESSEIkYEYPDMSQFVNDMQVMCNMIADGPLKSFCYRRLCYLSSKYQM 168
Cdd:PLN02768 279 PNPNPFSYTPEGKSDHYFEMQDGVVHVYANKDSKEEL-FPVADATTFFTDLHHILRVIAAGNIRTLCHHRLNLLEQKFNL 357
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 169 HVLLNELRELAAQKAVPHRDFYNTRKVDTHIHAASCMNQKHLLRFIKKTLKNNANEVVTVTNGQQMTLAQVFQSMNLTTY 248
Cdd:PLN02768 358 HLMLNADREFLAQKSAPHRDFYNVRKVDTHVHHSACMNQKHLLRFIKSKLRKEPDEVVIFRDGTYLTLKEVFESLDLTGY 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 249 DLTVDMLDVHADRNTFHRFDKFNSKYNPIGESRLREVFLKTDNYLNGKYFAQIIKEVAFDLEESKYQNAELRLSIYGKSP 328
Cdd:PLN02768 438 DLNVDLLDVHADKSTFHRFDKFNLKYNPCGQSRLREIFLKQDNLIQGRFLAELTKQVFSDLEASKYQMAEYRISIYGRKQ 517
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 329 DEWYKLAKWAIDNDVYSSNIRWLIQIPRLFDIFKSNKMMKSFQEILNNIFLPLFEATARPSKHPELHRFLQYVIGFDSVD 408
Cdd:PLN02768 518 SEWDQLASWIVNNELYSENVVWLIQLPRLYNVYKEMGIVTSFQNILDNIFIPLFEVTVDPDSHPQLHVFLKQVVGLDLVD 597
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 409 DESKPE-NPlfDNDVPRPEEWTYEENPPYAYYIYYMYANMTVLNKFRQSRNMNTFVLRPHCGEAGPVQHLVCGFLMAENI 487
Cdd:PLN02768 598 DESKPErRP--TKHMPTPAQWTNVFNPAFSYYVYYCYANLYTLNKLRESKGMTTIKFRPHSGEAGDIDHLAATFLTCHNI 675
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 488 SHGLLLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLNYHRNPLPEYLARGLIISLSTDDPLQFHFTKEPLMEEYSIAAQVW 567
Cdd:PLN02768 676 AHGINLRKSPVLQYLYYLAQIGLAMSPLSNNSLFLDYHRNPFPMFFLRGLNVSLSTDDPLQIHLTKEPLVEEYSIAASVW 755
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 281360851 568 KLSSCDMCELARNSVMMSGFPHAIKQQWLGPIYYEDGIMGNDITRTNVPEIRVAYRYETLLDELSNIF 635
Cdd:PLN02768 756 KLSSCDLCEIARNSVYQSGFSHALKSHWIGKEYYKRGPDGNDIHKTNVPHIRVEFRDTIWKEEMQQVY 823
|
|
| PTZ00310 |
PTZ00310 |
AMP deaminase; Provisional |
130-631 |
3.38e-177 |
|
AMP deaminase; Provisional
Pssm-ID: 240354 [Multi-domain] Cd Length: 1453 Bit Score: 542.09 E-value: 3.38e-177
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 130 PDMSQFVNDMQVMCNMIADGPLKSFCYRRLCYLSSKYQMHVLLNELRELAA--QKAVPHRDFYNTRKVDTHIHAASCMNQ 207
Cdd:PTZ00310 780 PTLTEFIRDLSELRDICSSVEVKRLATKRLENLEHKFRLHLALNHSNEAGTteERESSNRDFYQAYKVDTHIHMAAGMTA 859
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 208 KHLLRFIKKTLKNNANEVVTVTNGQQMTLAQVFqSMNLTTYDLTVDMLDVHADRNTFHRFDKFNSKYNPIGESRLREVFL 287
Cdd:PTZ00310 860 RQLLEFVVDKLLESGDDIAFKRGDHIVTLGQLF-SKYGITPNLTVDQLNVQADHTLFERFDNFNSKYNPMENPDLRSLLL 938
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 288 KTDNYLNGKYFAQIIKEVAFDLEESKYQNAELRLSIYGKSPDEWYKLAKWAIDNDVYSSNIRWLIQIPRLFDIFKSNKMM 367
Cdd:PTZ00310 939 KTDNFMKGRYFAELIKDVFEQYSRDRFTYAENRLSIYGINVKEWDDLAHWFDTHGMASKHNKWMIQVPRVYKVFRAQNVI 1018
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 368 KSFQEILNNIFLPLFEATARPSKHPELHRFLQYVIGFDSVDDESKPENPLFDNDvprPEEWTYEENPPYAYYIYYMYANM 447
Cdd:PTZ00310 1019 GSFGQYLDNIFQPLWEASLHPSKHPKFHYFLNHVSGFDSVDNEATIDLPFTDVS---PWAWTSVENPPYNYYLYYLYANI 1095
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 448 TVLNKFRQSRNMNTFVLRPHCGEAGPVQHLVCGFLMAENISHGLLLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLNYHRN 527
Cdd:PTZ00310 1096 RTLNEFRASRGFSTFALRPHCGESGSMDHLYGAFLCANSICHGINLRNDPPMQYLYYLAQIGLHVSPLSNNALFLAFLEN 1175
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 528 PLPEYLARGLIISLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSSCDMCELARNSVMMSGFPHAIKQQWLGPIYYEDGIMG 607
Cdd:PTZ00310 1176 PFPVFFHRGLNVSLSTDDPLMFHQTQEPLIEEYSIAARVWGLSLNDLCEIARNSVLQSGFDAAFKRNAIGDRWYLSSSLG 1255
|
490 500
....*....|....*....|....
gi 281360851 608 NDITRTNVPEIRVAYRYETLLDEL 631
Cdd:PTZ00310 1256 NDSLRTHLSDIRVAFRFETYHTEL 1279
|
|
| PTZ00310 |
PTZ00310 |
AMP deaminase; Provisional |
9-630 |
1.18e-77 |
|
AMP deaminase; Provisional
Pssm-ID: 240354 [Multi-domain] Cd Length: 1453 Bit Score: 270.14 E-value: 1.18e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 9 NFQRVSISGEDtSGVpleDLERASTLLIEALRLRSHYMamsdqsfpsttarflktvKLKDRINNLPVKEVSDVHlrhspm 88
Cdd:PTZ00310 64 TMFRVVIDGDD-GGV---DMRKVHGRIAAAIRVRQLYK------------------PTDTKVPEGEREQPSDST------ 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 89 kitnpwnvefPNDEDFKIKPLNGVFHIyenDDESSEIKYEYPdMSQFVNDMQVMCNMIADGPLKSFCYRRLCYLSSKYQM 168
Cdd:PTZ00310 116 ----------PMPSLVTIVQRDGVYRF---SGMDTSVVLPPP-WEQYVRDVQAVYLTVGNGPCLSACRHRLTIIQERSRM 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 169 HVLLNELRElaaQKAVPHRD---FYNTRKVDTHIHAASCMNQKHLLRFIKKTLKNNANEVVTVTNGQQMTLAQVFQSMNL 245
Cdd:PTZ00310 182 FFLLNAEIE---ERADLYKAggvFSPCTKVDNAVLLSTSVDAQELLEFVVTTYREQPRAPLRLRDGSNSTLREYLEAHGV 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 246 TTYD-LTVDMLDVHA--DRNTFHRFDKFNSKyNPIGE--SRLREVFLKTDNYLNGKyfaqIIKEVAFDLEESKY--QNAE 318
Cdd:PTZ00310 259 RDPReLTVEGLGWQPtkYRNKYGQYDLFDAK-NPMGAlgAELRQSFLSLHGNLCGK----LLRRELERREYQKQqpQATE 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 319 LRLSIYGKSPDEWYKLAKWAIDNDVYS-SNIRWLIQI--PRLFDiFKSNKMMKSFQEILNNIFLPLFEATARPS--KHPE 393
Cdd:PTZ00310 334 YSLPLYGHHPEELTDLAEWVRRQGFGPfSRNRWILAIsfKELGP-FQVPSSCTTVQDQLDNIFLPLFKATLCPSdpQWSD 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 394 LHRFLQYVIGFdSVDDESKPENPLFDNDVPRPEEWTYEENPPYAYYIYYMYANMTVLNKFRQSRNMNTFVLRPHCGEAGP 473
Cdd:PTZ00310 413 VAWLLCQVGGL-QILTHAVVRSEDFDETAPDPDQVPYTAKCSDLYYFYYVYANLAVLNSLRKRKGLNTLQLRPSGEKAPA 491
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 474 VQHLVCGFLMAENISHGLLLRKVPVLQYLYYLTQIGIAMSPLSNNSL-FLNYHRNPLPEYLARGLIISLSTDDPLQFHFT 552
Cdd:PTZ00310 492 YDQLISSYLLGDVITRATSIADYPVLQYLCGLHRVGLTVSPLRDHALsITAYFDHPLPKFLHRCLRVSISTSDPLYFHHH 571
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 281360851 553 KEPLMEEYSIAAQVWKLSSCDMCELARNSVMMSGFPHAIKQQWLGPIyYEDGIMGNDITRTNVPEIRVAYRYETLLDE 630
Cdd:PTZ00310 572 SQPLIEEYATAMKLFSLSPLDTTELARNSVLNSSFPPEVKQQWLGER-FQLGVEGNDFERSGVTNYRLAFREEAWALE 648
|
|
| ADA_AMPD |
cd00443 |
Adenosine/AMP deaminase. Adenosine deaminases (ADAs) are present in pro- and eukaryotic ... |
193-599 |
2.42e-62 |
|
Adenosine/AMP deaminase. Adenosine deaminases (ADAs) are present in pro- and eukaryotic organisms and catalyze the zinc dependent irreversible deamination of adenosine nucleosides to inosine nucleosides and ammonia. The eukaryotic AMP deaminase catalyzes a similar reaction leading to the hydrolytic removal of an amino group at the 6 position of the adenine nucleotide ring, a branch point in the adenylate catabolic pathway.
Pssm-ID: 238250 Cd Length: 305 Bit Score: 209.13 E-value: 2.42e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 193 RKVDTHIHAASCMNQKHLLRFIKKtlknnanevvtvtngqqmtlaqvfqsmnlttydltvdmldvhadrntfhrfdkfns 272
Cdd:cd00443 2 PKVELHAHLSGSISPETLLELIKK-------------------------------------------------------- 25
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 273 kynpigesRLREVFLKTDNYL-NGKYFAQIIKEVAFDLEESKYQNAELRLSIYGKSP-DEWYKLAKWAIDNDVYSSNIRW 350
Cdd:cd00443 26 --------EFFEKFLLVHNLLqKGEALARALKEVIEEFAEDNVQYLELRTTPRLLETeKGLTKEQYWLLVIEGISEAKQW 97
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 351 L--IQIPRLFDIfksNKMMKSFQEILNNiflplfeatarpSKHPELHRFL-QYVIGFDSVDDESKPENPlfdndvprPEE 427
Cdd:cd00443 98 FppIKVRLILSV---DRRGPYVQNYLVA------------SEILELAKFLsNYVVGIDLVGDESKGENP--------LRD 154
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 428 WT--YEEnppyayyiyymyanmtvLNKFRQsrnmntFVLRPHCGEAGPVQHLVCGF-LMAENISHGLLLRKVPVLQYLYY 504
Cdd:cd00443 155 FYsyYEY-----------------ARRLGL------LGLTLHCGETGNREELLQALlLLPDRIGHGIFLLKHPELIYLVK 211
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 505 LTQIGIAMSPLSNNSLFL--NYHRNPLPEYLARGLIISLSTDDPLQFHFtkePLMEEYSIAAQVWKLSSCDMCELARNSV 582
Cdd:cd00443 212 LRNIPIEVCPTSNVVLGTvqSYEKHPFMRFFKAGLPVSLSTDDPGIFGT---SLSEEYSLAAKTFGLTFEDLCELNRNSV 288
|
410
....*....|....*..
gi 281360851 583 MMSGFPHAIKQQWLGPI 599
Cdd:cd00443 289 LSSFAKDEEKKSLLEVL 305
|
|
| Add |
COG1816 |
Adenosine deaminase [Nucleotide transport and metabolism]; Adenosine deaminase is part of the ... |
453-596 |
3.11e-16 |
|
Adenosine deaminase [Nucleotide transport and metabolism]; Adenosine deaminase is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 441421 Cd Length: 326 Bit Score: 80.13 E-value: 3.11e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 453 FRQSRNMNtFVLRPHCGEAGPVQHL-----VCGflmAENISHGL-------LLRkvpvlqylyYL--TQIGIAMSPLSNN 518
Cdd:COG1816 174 FARAREAG-LHLTAHAGEAGGPESIwealdLLG---AERIGHGVraiedpaLVA---------RLadRGIPLEVCPTSNV 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 519 SL--FLNYHRNPLPEYLARGLIISLSTDDPLQFHFTkepLMEEYSIAAQVWKLSSCDMCELARNSVMMSGFPHAIKQQWL 596
Cdd:COG1816 241 QLgvVPSLAEHPLRRLLDAGVRVTLNTDDPLYFGTT---LTDEYELAAEAFGLSDADLAQLARNAIEASFLPEEEKAALL 317
|
|
| PRK09358 |
PRK09358 |
adenosine deaminase; Provisional |
453-596 |
1.31e-11 |
|
adenosine deaminase; Provisional
Pssm-ID: 236480 Cd Length: 340 Bit Score: 66.35 E-value: 1.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 453 FRQSRNMNtfvLR--PHCGEAGPVQHL-----VCGflmAENISHGL-------LLRkvpvlqylyYL--TQIGIAMSPLS 516
Cdd:PRK09358 188 FDRARDAG---LRltAHAGEAGGPESIwealdELG---AERIGHGVraiedpaLMA---------RLadRRIPLEVCPTS 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 517 NNSL--FLNYHRNPLPEYLARGLIISLSTDDPLQFHFTkepLMEEYSIAAQVWKLSSCDMCELARNSVMMSGFPHAIKQQ 594
Cdd:PRK09358 253 NVQTgaVPSLAEHPLKTLLDAGVRVTINTDDPLVFGTT---LTEEYEALAEAFGLSDEDLAQLARNALEAAFLSEEEKAA 329
|
..
gi 281360851 595 WL 596
Cdd:PRK09358 330 LL 331
|
|
| ADA |
cd01320 |
Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the ... |
466-596 |
5.57e-11 |
|
Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in the purine pathway. Low, as well as high levels of ADA activity have been linked to several diseases.
Pssm-ID: 238645 Cd Length: 325 Bit Score: 64.15 E-value: 5.57e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 466 PHCGEAGPVQHL-----VCGflmAENISHGLLLRKVPVLQYLYYLTQIGIAMSPLSNnsLFL----NYHRNPLPEYLARG 536
Cdd:cd01320 191 AHAGEAGGPESVrdaldLLG---AERIGHGIRAIEDPELVKRLAERNIPLEVCPTSN--VQTgavkSLAEHPLRELLDAG 265
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 537 LIISLSTDDPLQFHFTkepLMEEYSIAAQVWKLSSCDMCELARNSVMMSGFPHAIKQQWL 596
Cdd:cd01320 266 VKVTINTDDPTVFGTY---LTDEYELLAEAFGLTEEELKKLARNAVEASFLSEEEKAELL 322
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|
| metallo-dependent_hydrolases |
cd01292 |
Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a ... |
463-578 |
5.24e-10 |
|
Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a conserved metal binding site, involving four histidines and one aspartic acid residue. In the common reaction mechanism, the metal ion (or ions) deprotonate a water molecule for a nucleophilic attack on the substrate. The family includes urease alpha, adenosine deaminase, phosphotriesterase dihydroorotases, allantoinases, hydantoinases, AMP-, adenine and cytosine deaminases, imidazolonepropionase, aryldialkylphosphatase, chlorohydrolases, formylmethanofuran dehydrogenases and others.
Pssm-ID: 238617 [Multi-domain] Cd Length: 275 Bit Score: 60.81 E-value: 5.24e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 463 VLRPHCGEAGPVQHLVcGFLMA-------ENISHGLLLrkVPVLQYLYYLTQIGIAMSPLSNNSLFLN-YHRNPLPEYLA 534
Cdd:cd01292 148 PVVIHAGELPDPTRAL-EDLVAllrlggrVVIGHVSHL--DPELLELLKEAGVSLEVCPLSNYLLGRDgEGAEALRRLLE 224
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 281360851 535 RGLIISLSTDDPlqFHFTKEPLMEEYSIAAQVWKL--SSCDMCELA 578
Cdd:cd01292 225 LGIRVTLGTDGP--PHPLGTDLLALLRLLLKVLRLglSLEEALRLA 268
|
|
| ADGF |
cd01321 |
Adenosine deaminase-related growth factors (ADGF), a novel family of secreted growth-factors ... |
467-594 |
1.30e-05 |
|
Adenosine deaminase-related growth factors (ADGF), a novel family of secreted growth-factors with sequence similarty to adenosine deaminase.
Pssm-ID: 238646 Cd Length: 345 Bit Score: 47.65 E-value: 1.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 281360851 467 HCGE-----AGPVQHLVCGFLM-AENISHGLLLRKVPVLQYLYYLTQIGIAMSPLSN--NSLFLNYHRNPLPEYLARGLI 538
Cdd:cd01321 200 HAGEtngdgTETDENLVDALLLnTKRIGHGFALPKHPLLMDLVKKKNIAIEVCPISNqvLGLVSDLRNHPAAALLARGVP 279
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 281360851 539 ISLSTDDPLQFHFTkePLMEEYSIAAQVWKLSSCDMC---ELARNSVMMSGFPHAIKQQ 594
Cdd:cd01321 280 VVISSDDPGFWGAK--GLSHDFYQAFMGLAPADAGLRglkQLAENSIRYSALSDQEKDE 336
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