NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|24652508|ref|NP_724958|]
View 

pipsqueak, isoform D [Drosophila melanogaster]

Protein Classification

BTB/POZ domain-containing protein( domain architecture ID 10269253)

BTB (BR-C, ttk and bab)/POZ (Pox virus and Zinc finger) domain-containing protein, similar to Drosophila melanogaster protein pipsqueak (PsqA), a nuclear BTB-domain-containing protein required early in oogenesis

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
HTH_psq pfam05225
helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak ...
 470-513 2.80e-13

helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak protein of Drosophila melanogaster. In pipsqueak this domain binds to GAGA sequence.


:

Pssm-ID: 283007  Cd Length: 45  Bit Score: 64.25  E-value: 2.80e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 24652508   470 SEDAMNEALNSVRVGQMSINQAAIHYNLPYSSLYgRFKRGKYDV 513
Cdd:pfam05225   1 TPEALAEALEAVRNGQMSIRKAARIYGIPYSTLW-RRKRGKYSL 43
HTH_psq pfam05225
helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak ...
 418-463 1.03e-11

helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak protein of Drosophila melanogaster. In pipsqueak this domain binds to GAGA sequence.


:

Pssm-ID: 283007  Cd Length: 45  Bit Score: 60.01  E-value: 1.03e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 24652508   418 TPEDLERALEAIRAGNTSVQKASAEFGIPTGTLYgRCKREGIELSR 463
Cdd:pfam05225   1 TPEALAEALEAVRNGQMSIRKAARIYGIPYSTLW-RRKRGKYSLKR 45
HTH_psq pfam05225
helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak ...
 364-401 8.61e-09

helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak protein of Drosophila melanogaster. In pipsqueak this domain binds to GAGA sequence.


:

Pssm-ID: 283007  Cd Length: 45  Bit Score: 51.54  E-value: 8.61e-09
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 24652508   364 EDALQNALEALRSGQISANKASKAFGIPSSTLYKIARR 401
Cdd:pfam05225   2 PEALAEALEAVRNGQMSIRKAARIYGIPYSTLWRRKRG 39
HTH_psq super family cl04999
helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak ...
 309-344 1.09e-06

helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak protein of Drosophila melanogaster. In pipsqueak this domain binds to GAGA sequence.


The actual alignment was detected with superfamily member pfam05225:

Pssm-ID: 283007  Cd Length: 45  Bit Score: 45.76  E-value: 1.09e-06
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 24652508   309 TQDDMNSALDALKNQNMSLTKASAIYGIPSTTLWQR 344
Cdd:pfam05225   1 TPEALAEALEAVRNGQMSIRKAARIYGIPYSTLWRR 36
 
Name Accession Description Interval E-value
HTH_psq pfam05225
helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak ...
 470-513 2.80e-13

helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak protein of Drosophila melanogaster. In pipsqueak this domain binds to GAGA sequence.


Pssm-ID: 283007  Cd Length: 45  Bit Score: 64.25  E-value: 2.80e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 24652508   470 SEDAMNEALNSVRVGQMSINQAAIHYNLPYSSLYgRFKRGKYDV 513
Cdd:pfam05225   1 TPEALAEALEAVRNGQMSIRKAARIYGIPYSTLW-RRKRGKYSL 43
HTH_psq pfam05225
helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak ...
 418-463 1.03e-11

helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak protein of Drosophila melanogaster. In pipsqueak this domain binds to GAGA sequence.


Pssm-ID: 283007  Cd Length: 45  Bit Score: 60.01  E-value: 1.03e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 24652508   418 TPEDLERALEAIRAGNTSVQKASAEFGIPTGTLYgRCKREGIELSR 463
Cdd:pfam05225   1 TPEALAEALEAVRNGQMSIRKAARIYGIPYSTLW-RRKRGKYSLKR 45
HTH_psq pfam05225
helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak ...
 364-401 8.61e-09

helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak protein of Drosophila melanogaster. In pipsqueak this domain binds to GAGA sequence.


Pssm-ID: 283007  Cd Length: 45  Bit Score: 51.54  E-value: 8.61e-09
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 24652508   364 EDALQNALEALRSGQISANKASKAFGIPSSTLYKIARR 401
Cdd:pfam05225   2 PEALAEALEAVRNGQMSIRKAARIYGIPYSTLWRRKRG 39
HTH_psq pfam05225
helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak ...
 309-344 1.09e-06

helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak protein of Drosophila melanogaster. In pipsqueak this domain binds to GAGA sequence.


Pssm-ID: 283007  Cd Length: 45  Bit Score: 45.76  E-value: 1.09e-06
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 24652508   309 TQDDMNSALDALKNQNMSLTKASAIYGIPSTTLWQR 344
Cdd:pfam05225   1 TPEALAEALEAVRNGQMSIRKAARIYGIPYSTLWRR 36
 
Name Accession Description Interval E-value
HTH_psq pfam05225
helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak ...
 470-513 2.80e-13

helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak protein of Drosophila melanogaster. In pipsqueak this domain binds to GAGA sequence.


Pssm-ID: 283007  Cd Length: 45  Bit Score: 64.25  E-value: 2.80e-13
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 24652508   470 SEDAMNEALNSVRVGQMSINQAAIHYNLPYSSLYgRFKRGKYDV 513
Cdd:pfam05225   1 TPEALAEALEAVRNGQMSIRKAARIYGIPYSTLW-RRKRGKYSL 43
HTH_psq pfam05225
helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak ...
 418-463 1.03e-11

helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak protein of Drosophila melanogaster. In pipsqueak this domain binds to GAGA sequence.


Pssm-ID: 283007  Cd Length: 45  Bit Score: 60.01  E-value: 1.03e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 24652508   418 TPEDLERALEAIRAGNTSVQKASAEFGIPTGTLYgRCKREGIELSR 463
Cdd:pfam05225   1 TPEALAEALEAVRNGQMSIRKAARIYGIPYSTLW-RRKRGKYSLKR 45
HTH_psq pfam05225
helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak ...
 364-401 8.61e-09

helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak protein of Drosophila melanogaster. In pipsqueak this domain binds to GAGA sequence.


Pssm-ID: 283007  Cd Length: 45  Bit Score: 51.54  E-value: 8.61e-09
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 24652508   364 EDALQNALEALRSGQISANKASKAFGIPSSTLYKIARR 401
Cdd:pfam05225   2 PEALAEALEAVRNGQMSIRKAARIYGIPYSTLWRRKRG 39
HTH_psq pfam05225
helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak ...
 309-344 1.09e-06

helix-turn-helix, Psq domain; This DNA-binding motif is found in four copies in the pipsqueak protein of Drosophila melanogaster. In pipsqueak this domain binds to GAGA sequence.


Pssm-ID: 283007  Cd Length: 45  Bit Score: 45.76  E-value: 1.09e-06
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 24652508   309 TQDDMNSALDALKNQNMSLTKASAIYGIPSTTLWQR 344
Cdd:pfam05225   1 TPEALAEALEAVRNGQMSIRKAARIYGIPYSTLWRR 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH