|
Name |
Accession |
Description |
Interval |
E-value |
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
205-674 |
3.19e-139 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 413.96 E-value: 3.19e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 205 ILGLYMLIIFDVIDHTFAALIIATTAVaILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRI 284
Cdd:cd01116 1 FIITYALIIFEKVHRTVAALAGALWLV-ILGLATLSPDLETIVSWVDWETLALLLGMMIIVSILSETGVFEYLAIWAVKI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 285 SRGRPWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIVTTspv 364
Cdd:cd01116 80 SKGRPWRLLLLLGLLTAFLSAFLDNVTTVLLMVPVTIRLCEVLGLNPVPVLISEVIAANIGGAATLIGDPPNIMIGS--- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 365 avAEGVDFAHFIIHMMPGVLAAMFVVFGIIYVTHRKSIFVLDQNQLDLMeerargkkppsqetldriallkgslpgkywl 444
Cdd:cd01116 157 --AAGLTFNDFLLHMLPSVVLALVVTFILLYFLYRNILKAREEDVLALA------------------------------- 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 445 rpvegypetlaELEASSRILDKPLLVRCCIALIFAFLCMLLHSIPKVadgaSLGWVTLLAAFLLIILDDKNDLNATLGII 524
Cdd:cd01116 204 -----------ELEPKYPIKDKVLLLKSLTILTLVIIGFVLHSPLGV----SLGWIALLGALLLLLLADKLDFEDVLSRV 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 525 QWTILLFIAALFVLSEAVDQLGFFEWLGDRTVGFLRslepqNQIAVTTMVILWTTALLTIFIDNAAVTIFMLKFSIEMAS 604
Cdd:cd01116 269 EWDTLLFFAGLFVLVGGLEELGIIEWIAELLVGVIL-----GRIAVAVILILWISALLSAFIDNIPVTATMIPIVKDLAS 343
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 605 NDDIPLPPMFWALTFGACFGGNGSLFGAVSNEIIALIALQHGYKISFWHFFAIGFPLMLVTMVIGSGYLL 674
Cdd:cd01116 344 QLGIPLLPLWWALALGACLGGNGTLIGASANVVAAGIAEQHGYKISFWEFLKVGFPIMLVSLILATVYLL 413
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
201-677 |
5.81e-63 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 215.38 E-value: 5.81e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 201 AGLLILGLYMLIIFD--VIDHTFAALIIATTAVAILAIlehrpSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLV 278
Cdd:COG1055 5 ALAIFVLTYLLIILEprGLNRAVAALLGAALLLLLGVV-----SLEDALEAIDWNTILFLLGMMIIVAILDESGFFEWLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 279 VWTYRISRGRPWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAI 358
Cdd:COG1055 80 IKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLNPVPFLIAIVFAANIGGAATPIGNPTNIM 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 359 vttspVAVAEGVDFAHFIIHMMPGVLAAMFVVFGIIYVTHRKSIFVldqnqldlmeerargkkppsqetldriallkgsl 438
Cdd:COG1055 160 -----IASAGGLSFLDFLANLFPPSLVSLLVTLLVLYLLFRKELPA---------------------------------- 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 439 pgkywlrpvegypETLAELEASSRILDKPLLVRCCIALIFAFLCMLLHSIPKVAD------GASLGWVTLlaaflliild 512
Cdd:COG1055 201 -------------APDLEDDPKEAIKDRRLLRISLLVLALLLVGFVLHSFLGLPPaliallGAAVLLLLA---------- 257
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 513 dKNDLNATLGIIQWTILLFIAALFVLSEAVDQLGFFEWLGDrtvgFLRSLEPQNqIAVTTMVILWTTALLTIFIDNAAVT 592
Cdd:COG1055 258 -RVDVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAE----LLASLTGGN-LLLAALLILWLSAILSAVVDNVPLV 331
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 593 IFMLKFSIEMASNDDipLPPMFWALTFGACFGGNGSLFGAVSNEIIALIALQHGYKISFWHFFAIGFPLMLVTMVIGSGY 672
Cdd:COG1055 332 AALLPLIPDLGATGN--PEPLWLALALGATLGGNLTPIGSAANVIVLGIAEKKGIKISFGEFLKVGLPLTLLTLLIALLY 409
|
....*
gi 62484377 673 LLIAH 677
Cdd:COG1055 410 LLLLY 414
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
209-620 |
2.63e-51 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 181.36 E-value: 2.63e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 209 YMLIIFDVIDHTFAALIiattaVAILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRISRGR 288
Cdd:pfam03600 1 YVLIITEKLPRDVVALL-----GAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 289 PWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIvttspVAVAE 368
Cdd:pfam03600 76 PRRLLVALMLATALLSAFLSNDGTVLIMIPIVLALARRLGLPPSPLLIALAFAANIGGTATPIGDPPNII-----IASAL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 369 GVDFAHFIIHMMPGVLAAMFVV-FGIIYVTHRKSIFVLDQNQLDLMEERARGKKppsqetldriallkgslpgkywlrpv 447
Cdd:pfam03600 151 GLSFGDFGFFMFPPVGVALLLVgLLPLLLIFRKLLPVRKEEEAELEELRKRAIK-------------------------- 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 448 egypetlaeleassrilDKPLLVRCCIALIFAFLCMLLHSIPKVADGASLGWVtllaaflliildDKNDLNATLGIIQWT 527
Cdd:pfam03600 205 -----------------DKLLLAISALVLALVILGFLLLSVLALAGALLLLLT------------GVLDPEEALKAVDWS 255
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 528 ILLFIAALFVLSEAVDQLGFFEWLGDrtvgflrSLEPQNQIAVTTMVILWTTALLTIFIDNAAVTIFMLKFSIEMASNDD 607
Cdd:pfam03600 256 TLLFFAGLFILVGALEKTGLADALAD-------ALGGLSGLLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAG 328
|
410
....*....|....
gi 62484377 608 I-PLPPMFWALTFG 620
Cdd:pfam03600 329 LgDPDPLAWALAVG 342
|
|
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
232-669 |
2.89e-14 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 75.80 E-value: 2.89e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 232 AILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFL-VVWTYRISRGRPwpLIFFLSMLTAFLSAFLNSD 310
Cdd:PLN00136 43 AVLMIVFHVISPDDAYASIDLPILGLLFATMVVGSYLKNAGMFKHLgRLLAWRSQGGRD--LLCRVCVVTALASALFTND 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 311 IMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIvttspVAVAEGVDFAHFIIHMMPGVLAAMFVV 390
Cdd:PLN00136 121 TCCVVLTEFVLELAAERNLPAKPFLLALASSANIGSSATPIGNPQNLV-----IAFNSKITFPKFLLGILPAMLAGMAVN 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 391 FGIIYVTHRKSI-----FVLDQNQLDLMEErarGKKPPSQETL--DRIALLKGSLpgkywlrpvEGYPETLAELEASSRI 463
Cdd:PLN00136 196 MVMLLCMYWKDLdggaeLSVDGKQMEAVEE---GRSPASAKSTkqQSPALLQAGL---------NGDGNGDMSSMMSENI 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 464 LDK-PLLVRCCIALIFAFLCMLLHSIP-----KVADGASLGWvTLLAAFLLIILDDKNDLNATLGIIQWTILLFIAALFV 537
Cdd:PLN00136 264 STKhPWFMQCTEHRRKLFLKSFAYVVTvgmvvAYMVGLNMSW-TAITTAIALVVVDFRDAEPCLDTVSYSLLVFFSGMFI 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 538 LSEAVDQLGffewLGDRTVGFLRSLEPQNQ---IAVTTMVILwttaLLTIFIDNAAVTIFMlkfSIEMASNDDIPLPPMF 614
Cdd:PLN00136 343 TVSGFNKTG----LPGAIWNFMAPYSKVNSvggISVLSVIIL----LLSNLASNVPTVLLM---GDEVAAAAALISPAAV 411
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 62484377 615 ---W-ALTFGACFGGNGSLFGAVSNEII---ALIALQHGYKISFWHFFAIGFPLMLVTMVIG 669
Cdd:PLN00136 412 trsWlLLAWVSTVAGNLSLLGSAANLIVceqARRAPRNAYDLTFWQHIVFGVPSTLIVTAIG 473
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
204-625 |
9.55e-06 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 48.49 E-value: 9.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 204 LILGLYMLIIFDVIDHTFAALIIATTAVAILAIL----EHRPSMRAIVSFVNfEPLMLLFGLMTIVDIMATTGVFDFLVV 279
Cdd:TIGR00785 12 LLLAIFVAAIVGWILEPLPLPVTALLAIPIIAVLlgvlSAFKFKNALSGFAD-PTIWLFFGAFILATALVKTGLGKRIAY 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 280 WTYRISRGRPWPLIFFLSMLTAFLSAFL--NSDIMALSLTPITIRLC------EEMSLRT--SYVLVVMAIFADMGGALT 349
Cdd:TIGR00785 91 KLVGKMGGTTLGLGYFLVFLETLLAPMWpsNTARAGGILLPIIKSLLpllgskPEKSPRKigKYLMLGIAYSASIGSSGF 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 350 PLGNPPNAIVT--TSPVAVAEgVDFAHFIIHMMPGVLAAMFVVFGIIYVTHR-KSIFVLDQNQLDLMEERARGKKPPSQE 426
Cdd:TIGR00785 171 LTGSAPNALAAgiLSKILGIQ-ISWGDWFLAGLPLGIILLLLVPLLLYVLFPpELKLKDEVDLWAKEELEEMGPMSFREK 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 427 TLDRIALLKGSLpgkyWlrpvegypetlaeleassrILDKPLLVRCCIALIFAFLCMLLHSIpkvadgasLGWvtllaaf 506
Cdd:TIGR00785 250 ALLGIFLLALLL----W-------------------IFGGSLGINASVVALLAVVLMLFLGI--------VTW------- 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 507 lliilddkNDLNAtlGIIQWTILLFIAALFVLSEAVDQLGFFEWLGDRTVGFLRSLEPQNQIAVTTMVIlwtTALLTIFI 586
Cdd:TIGR00785 292 --------KDIQK--NKVAWNTLILFGGLIGLAGGLKKSGFIKWFSEKLVGILDGLSPTIAVLVLVVLF---YIILYFFA 358
|
410 420 430
....*....|....*....|....*....|....*....
gi 62484377 587 DNAAVTIFMLKFSIEMASNDDIPLPPMFWALTFGACFGG 625
Cdd:TIGR00785 359 SNTAHTAALVPIFFSVASAQGIPLELLALALALSASLMG 397
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| P_permease |
cd01116 |
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible ... |
205-674 |
3.19e-139 |
|
Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the intraorganelle pH, together with the ATP-driven proton pump. It shows significant sequence similarity to the Na+/H+ antiporter NhaD from Vibrio parahaemolyticus. Both proteins belong to ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease contains 8-13 transmembrane domains.
Pssm-ID: 238536 [Multi-domain] Cd Length: 413 Bit Score: 413.96 E-value: 3.19e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 205 ILGLYMLIIFDVIDHTFAALIIATTAVaILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRI 284
Cdd:cd01116 1 FIITYALIIFEKVHRTVAALAGALWLV-ILGLATLSPDLETIVSWVDWETLALLLGMMIIVSILSETGVFEYLAIWAVKI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 285 SRGRPWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIVTTspv 364
Cdd:cd01116 80 SKGRPWRLLLLLGLLTAFLSAFLDNVTTVLLMVPVTIRLCEVLGLNPVPVLISEVIAANIGGAATLIGDPPNIMIGS--- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 365 avAEGVDFAHFIIHMMPGVLAAMFVVFGIIYVTHRKSIFVLDQNQLDLMeerargkkppsqetldriallkgslpgkywl 444
Cdd:cd01116 157 --AAGLTFNDFLLHMLPSVVLALVVTFILLYFLYRNILKAREEDVLALA------------------------------- 203
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 445 rpvegypetlaELEASSRILDKPLLVRCCIALIFAFLCMLLHSIPKVadgaSLGWVTLLAAFLLIILDDKNDLNATLGII 524
Cdd:cd01116 204 -----------ELEPKYPIKDKVLLLKSLTILTLVIIGFVLHSPLGV----SLGWIALLGALLLLLLADKLDFEDVLSRV 268
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 525 QWTILLFIAALFVLSEAVDQLGFFEWLGDRTVGFLRslepqNQIAVTTMVILWTTALLTIFIDNAAVTIFMLKFSIEMAS 604
Cdd:cd01116 269 EWDTLLFFAGLFVLVGGLEELGIIEWIAELLVGVIL-----GRIAVAVILILWISALLSAFIDNIPVTATMIPIVKDLAS 343
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 605 NDDIPLPPMFWALTFGACFGGNGSLFGAVSNEIIALIALQHGYKISFWHFFAIGFPLMLVTMVIGSGYLL 674
Cdd:cd01116 344 QLGIPLLPLWWALALGACLGGNGTLIGASANVVAAGIAEQHGYKISFWEFLKVGFPIMLVSLILATVYLL 413
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
209-673 |
1.04e-73 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 243.31 E-value: 1.04e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 209 YMLIIFDVIDHTFAALIIATTAVAILAIlehrpSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRISRGR 288
Cdd:cd00625 1 YVLIRPEKLPRAVVALLGAVLLVLLGVV-----SPKEALSAIDWETILLLFGMMILSAALEETGLFDRLAAKLARASKGS 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 289 PWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIvttspVAVAE 368
Cdd:cd00625 76 RRLLLLLMLLTAALSAFFSNDATAVLLTPIVLALLRKLGLSPPVPLLLALAFAANIGGAATPIGNPPNLI-----IASLS 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 369 GVDFAHFIIHMMPGVLAAMFVVFGIIYVTHRKSIFVLDQNQldlmeerargkkppsqetldriallkgslpgkywlrpve 448
Cdd:cd00625 151 GLGFLDFLAFMAPPALGLLLLLLGLLYLLFRKKLLLPDEDK--------------------------------------- 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 449 gyPETLAELEASSRILDKPLLVRCCIALIFAFLCMLLHSIPKVAdgasLGWVTLLAAFLLIILDDKNDLNAtlgiIQWTI 528
Cdd:cd00625 192 --LTVLAEPLPARPLLKKFLLLALLLLLLFVLLFFFLIPLGLIA----LLGALLLLLLLVRGLDPEEVLKS----VDWGT 261
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 529 LLFIAALFVLSEAVDQLGFFEWLGDRTVGFLrslepQNQIAVTTMVILWTTALLTIFIDNAAVTIFMLKFSIEMAsnddi 608
Cdd:cd00625 262 LLFFAGLFVLVGALESTGLLEWLAELLVALV-----GLPPLAALLLIGLLSALLSNFISNVPTVALLLPIAASLA----- 331
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 62484377 609 PLPPMFWALTFGACFGGNGSLFGAVSNEIIALIALQHGYKISFWHFFAIGFPLMLVTMVIGSGYL 673
Cdd:cd00625 332 PPEPAWLALALGSTLGGNLTLIGSLANLIPLGAAENAGVGISFGEFLKVGLPLTLLSLVVSLLYL 396
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
201-677 |
5.81e-63 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 215.38 E-value: 5.81e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 201 AGLLILGLYMLIIFD--VIDHTFAALIIATTAVAILAIlehrpSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLV 278
Cdd:COG1055 5 ALAIFVLTYLLIILEprGLNRAVAALLGAALLLLLGVV-----SLEDALEAIDWNTILFLLGMMIIVAILDESGFFEWLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 279 VWTYRISRGRPWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAI 358
Cdd:COG1055 80 IKLARRAKGSPRRLLWLLGLLTALLSAFLDNDTTALLLTPVVLAIARRLGLNPVPFLIAIVFAANIGGAATPIGNPTNIM 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 359 vttspVAVAEGVDFAHFIIHMMPGVLAAMFVVFGIIYVTHRKSIFVldqnqldlmeerargkkppsqetldriallkgsl 438
Cdd:COG1055 160 -----IASAGGLSFLDFLANLFPPSLVSLLVTLLVLYLLFRKELPA---------------------------------- 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 439 pgkywlrpvegypETLAELEASSRILDKPLLVRCCIALIFAFLCMLLHSIPKVAD------GASLGWVTLlaaflliild 512
Cdd:COG1055 201 -------------APDLEDDPKEAIKDRRLLRISLLVLALLLVGFVLHSFLGLPPaliallGAAVLLLLA---------- 257
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 513 dKNDLNATLGIIQWTILLFIAALFVLSEAVDQLGFFEWLGDrtvgFLRSLEPQNqIAVTTMVILWTTALLTIFIDNAAVT 592
Cdd:COG1055 258 -RVDVREVLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAE----LLASLTGGN-LLLAALLILWLSAILSAVVDNVPLV 331
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 593 IFMLKFSIEMASNDDipLPPMFWALTFGACFGGNGSLFGAVSNEIIALIALQHGYKISFWHFFAIGFPLMLVTMVIGSGY 672
Cdd:COG1055 332 AALLPLIPDLGATGN--PEPLWLALALGATLGGNLTPIGSAANVIVLGIAEKKGIKISFGEFLKVGLPLTLLTLLIALLY 409
|
....*
gi 62484377 673 LLIAH 677
Cdd:COG1055 410 LLLLY 414
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
209-620 |
2.63e-51 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 181.36 E-value: 2.63e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 209 YMLIIFDVIDHTFAALIiattaVAILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRISRGR 288
Cdd:pfam03600 1 YVLIITEKLPRDVVALL-----GAVLLVLLGVLTPEEALSGIDSPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 289 PWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIvttspVAVAE 368
Cdd:pfam03600 76 PRRLLVALMLATALLSAFLSNDGTVLIMIPIVLALARRLGLPPSPLLIALAFAANIGGTATPIGDPPNII-----IASAL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 369 GVDFAHFIIHMMPGVLAAMFVV-FGIIYVTHRKSIFVLDQNQLDLMEERARGKKppsqetldriallkgslpgkywlrpv 447
Cdd:pfam03600 151 GLSFGDFGFFMFPPVGVALLLVgLLPLLLIFRKLLPVRKEEEAELEELRKRAIK-------------------------- 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 448 egypetlaeleassrilDKPLLVRCCIALIFAFLCMLLHSIPKVADGASLGWVtllaaflliildDKNDLNATLGIIQWT 527
Cdd:pfam03600 205 -----------------DKLLLAISALVLALVILGFLLLSVLALAGALLLLLT------------GVLDPEEALKAVDWS 255
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 528 ILLFIAALFVLSEAVDQLGFFEWLGDrtvgflrSLEPQNQIAVTTMVILWTTALLTIFIDNAAVTIFMLKFSIEMASNDD 607
Cdd:pfam03600 256 TLLFFAGLFILVGALEKTGLADALAD-------ALGGLSGLLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAG 328
|
410
....*....|....
gi 62484377 608 I-PLPPMFWALTFG 620
Cdd:pfam03600 329 LgDPDPLAWALAVG 342
|
|
| YbiR_permease |
cd01117 |
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to ... |
232-669 |
3.55e-31 |
|
Putative anion permease YbiR. Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate sodium, sulfate, arsenite and organic anions. A typical ArsB/NhaD permease is composed of 8-13 transmembrane domains.
Pssm-ID: 238537 [Multi-domain] Cd Length: 384 Bit Score: 125.85 E-value: 3.55e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 232 AILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRiSRGRPWPLIFFLSMLTAFLSAFLNSDI 311
Cdd:cd01117 21 AALMLLFGVISLEDAPAAIDLDTIILLFGLMVVSAALELSGFFDALGSRILV-KAGSPRRLLFLLVLLSGILSALLTNDT 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 312 MALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIvttspVAVAEGVDFAHFIIHMMPGVLAAMFVVF 391
Cdd:cd01117 100 ACLVFTPIVLELARVAGLPPIPLLLALATAANIGSAATPIGNPQNLL-----IASESGISFPFFLAAMAPLALLGLLLLL 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 392 GIIYVTHRKSIfvldqnqldlmEERARGKKPPSQETLDRIALLKGSLPgkywlrpvegypetlaeleassrildkpllvr 471
Cdd:cd01117 175 ILLLVLFPGEL-----------KGLPLDKATKEEGVGARKLAVKLLVL-------------------------------- 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 472 cCIALIFAFLCML-LHSIPKVAdgaslgwVTLLAAFLLIILDDKNdlnaTLGIIQWTILLFIAALFVLSEAVDQLGFFEW 550
Cdd:cd01117 212 -ILLLLVAFLALLgVIPLWTAA-------LVAAVLLLLTRLKPRR----VLKKVDWGLLLFFAGLFILVGGFAQGLPLEG 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 551 LgdrtvgfLRSLEPQNQIAvttmVILWTTALLTIFIDNAAVTIFMLKFSIEmasnddipLPPMFW-ALTFGACFGGNGSL 629
Cdd:cd01117 280 L-------SRLLPLLDSVL----SLFLVSIGLSQLISNVPAVLLLLPFLPS--------ADEKDWlLLAAGSTIAGNLTL 340
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 62484377 630 FGAVSNEIIALIALQHGYKISFWHFFAIGFPLMLVTMVIG 669
Cdd:cd01117 341 LGSAANLIVAEAAERRGVRLSFGEFLKYGVPLTLLTAAIG 380
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
259-675 |
1.14e-18 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 88.29 E-value: 1.14e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 259 FGLMTIVDIMATTGVFDFLVVWTYRISRGRPWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRT-----SY 333
Cdd:COG0471 1 LGGFVLAAALEKTGLGRRIALLLLKRFGGSPLRLLLGLMLATALLSAFISNTARAAMMLPIALSIAAALGSEKrskfgSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 334 VLVVMAIFADMGGALTPLGNPPNAIVTT-SPVAVAEGVDFAHFIIHMMPGVLAAMFVVFGIIYVTHRKSIFVLDQNQLDL 412
Cdd:COG0471 81 LLLPIAFAASIGGMGTLIGTPPNLIAAGlLEEATGIPISFFEWMLVGLPVALVGLLLLWLVLYRLLPPEIKEVPGSKEVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 413 MEERARGKKPPSQEtldRIALLKGSLPGKYW-LRPVEGYPETLaeleassrildkpllvrccIALIFAFLCMLLHSIpkv 491
Cdd:COG0471 161 REELAELGPLSRRE---KIALAIFALTVLLWiTGSLHGIPIAV-------------------VALLGAVLLLLTGVL--- 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 492 adgaslgwvtllaaflliildDKNDLNATlgiIQWTILLFIAALFVLSEAVDQLGFFEWLGDRTVGFLRSLEPqnqiAVT 571
Cdd:COG0471 216 ---------------------TWKDAYKS---IPWGVLLLFGGGLALGAALEKTGLAAWLADALLPLLGGLSP----LLL 267
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 572 TMVILWTTALLTIFIDNAAVTIFMLKFSIEMASNDDIPLPPMFWALTFGACFG-----GNGSlfgavsneiiALIALQHG 646
Cdd:COG0471 268 LLLLALLTLLLTEFASNTATAALLLPIAISLAQALGVNPLPLALAVAFAASCAfllpvGTPP----------NAIVYGSG 337
|
410 420
....*....|....*....|....*....
gi 62484377 647 YkISFWHFFAIGFPLMLVTMVIGSGYLLI 675
Cdd:COG0471 338 Y-YKFKDFLKVGLPLNLIGLVVLLLLGPL 365
|
|
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
232-669 |
2.89e-14 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 75.80 E-value: 2.89e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 232 AILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFL-VVWTYRISRGRPwpLIFFLSMLTAFLSAFLNSD 310
Cdd:PLN00136 43 AVLMIVFHVISPDDAYASIDLPILGLLFATMVVGSYLKNAGMFKHLgRLLAWRSQGGRD--LLCRVCVVTALASALFTND 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 311 IMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIvttspVAVAEGVDFAHFIIHMMPGVLAAMFVV 390
Cdd:PLN00136 121 TCCVVLTEFVLELAAERNLPAKPFLLALASSANIGSSATPIGNPQNLV-----IAFNSKITFPKFLLGILPAMLAGMAVN 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 391 FGIIYVTHRKSI-----FVLDQNQLDLMEErarGKKPPSQETL--DRIALLKGSLpgkywlrpvEGYPETLAELEASSRI 463
Cdd:PLN00136 196 MVMLLCMYWKDLdggaeLSVDGKQMEAVEE---GRSPASAKSTkqQSPALLQAGL---------NGDGNGDMSSMMSENI 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 464 LDK-PLLVRCCIALIFAFLCMLLHSIP-----KVADGASLGWvTLLAAFLLIILDDKNDLNATLGIIQWTILLFIAALFV 537
Cdd:PLN00136 264 STKhPWFMQCTEHRRKLFLKSFAYVVTvgmvvAYMVGLNMSW-TAITTAIALVVVDFRDAEPCLDTVSYSLLVFFSGMFI 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 538 LSEAVDQLGffewLGDRTVGFLRSLEPQNQ---IAVTTMVILwttaLLTIFIDNAAVTIFMlkfSIEMASNDDIPLPPMF 614
Cdd:PLN00136 343 TVSGFNKTG----LPGAIWNFMAPYSKVNSvggISVLSVIIL----LLSNLASNVPTVLLM---GDEVAAAAALISPAAV 411
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 62484377 615 ---W-ALTFGACFGGNGSLFGAVSNEII---ALIALQHGYKISFWHFFAIGFPLMLVTMVIG 669
Cdd:PLN00136 412 trsWlLLAWVSTVAGNLSLLGSAANLIVceqARRAPRNAYDLTFWQHIVFGVPSTLIVTAIG 473
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
221-676 |
4.66e-11 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 65.30 E-value: 4.66e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 221 FAALIIATTAVAI---LAILEHRPSMRAIVSFVNfEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRISRGRPWPLIFFLS 297
Cdd:cd01115 13 TEALPLDVTALLVpvlLVLLGVVPPKEAFSGFSD-PAVILFLAGFILGAALTRTGLAKRIATKLLKRAGKGERRLLLLLM 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 298 MLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMGGALTPLGNPPNAIVttSPVAVAEGVDFAHFII 377
Cdd:cd01115 92 LVTAFLSAFMSNTATVAIMLPVALGLAAKLDISPSRLLMPLAFAASIGGMLTLIGTPPNLVA--SGYLESLGGQGFSFFE 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 378 HMMPGVLAAMFVVFgIIYVTHRKSIFVLdqnqldlmeerargkkppsqetldRIALLKGSLPGKYWLrpvegypetlael 457
Cdd:cd01115 170 FTPIGLPLLIIGLL-YLWFIFRLAVLII------------------------TIVLLAALAAITGLL------------- 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 458 eassrildKPLLVRCCIALIFAFLCMLLhsipkvadgaslgwvtllaaflliildDKNDLNAtlgiIQWTILLFIAALFV 537
Cdd:cd01115 212 --------PVSVAIAIGAIVLVFGGVLL---------------------------TKEDYKS----IDWGIIFLFAGGIP 252
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 538 LSEAVDQLGFFEWLGDRTVGFLRSLEPqnqiAVTTMVILWTTALLTIFIDNAAVTIFMLKFSIEMASNDDIPLPPMFWAL 617
Cdd:cd01115 253 LGKALESSGAAALIAEALISLLGGLPP----FAILLLLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAV 328
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 62484377 618 TFGA--CFggnGSLFGAVSNeiiaLIALQHGYkISFWHFFAIGFPLMLVTMVIGSGYLLIA 676
Cdd:cd01115 329 AIGAscAF---MLPVGTPPN----AIVLGPGG-YKFSDFAKVGLPLSILSLVVSVTMIPLI 381
|
|
| ArsB_permease |
cd01118 |
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in ... |
258-667 |
1.06e-10 |
|
Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.
Pssm-ID: 238538 [Multi-domain] Cd Length: 416 Bit Score: 64.21 E-value: 1.06e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 258 LFGLMTIVDIMATTGVFDFLVVWTYRISRGRPWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLV- 336
Cdd:cd01118 58 LIGVILLSLLLDEEGFFEWVAALAARWARGSGRKLFTLIVLLGAAVTAFFANDGTALILTPIVIALLRALGAKKNRTLPf 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 337 --VMAIFADMGGALTPLGNPPNAIvttspVAVAEGVDFAHFIIHMMPGVLAAMFVVFGIIYVTHRKSIfvldqnqldlme 414
Cdd:cd01118 138 lyACAFIADAASLPLPISNLVNIV-----TAGYFGIGFTEYAALMFLPSIVSILATYVVLYLFFRRAL------------ 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 415 erargkkPPSQETldriallkgslpgkywlrpvegypetlAELEASSRILDKPLLVRCCIALIFAFLCMLLHSIPKVADG 494
Cdd:cd01118 201 -------PKRLET---------------------------ASVKKPSLAIKDPLLFGLAWTLLVLLVVSAFGVDILLIPP 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 495 ASLGWVTLLAAFLLIILDDKNDLNATLGIIQWTILLFIAALFVLSEAVDQLGFFEWLGDrtvgFLRSLEPQNQIAvTTMV 574
Cdd:cd01118 247 SFIAGVLALIFLLLARRGGAINPLKVLKEAPWGVLLFSLGLYVVVFGLKNAGLTAILAD----LLNWLVSQGLLA-AILG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 575 ILWTTALLTIFIDNAAVTIFMLkfsieMASNDDIPLPPMFWALTFGACFGGNGSLFGAVSNeIIALIAL-QHGYKISFWH 653
Cdd:cd01118 322 VGLLAAFLSNVMNNLPAVLIGA-----LALAAGHAPEALVYANLIGVDLGPKLTPIGSLAT-LLWLHVLrRKGIRVSWGY 395
|
410
....*....|....
gi 62484377 654 FFAIGFPLMLVTMV 667
Cdd:cd01118 396 YLKVGLIVTPPVLV 409
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
526-683 |
5.79e-10 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 61.56 E-value: 5.79e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 526 WTILLFIAALFVLSEAVDQLGFFEWLGDRTVGFLRSLEPQNQIAVTtmvilWTTALLTIFIDNAAVTIFMLKFSIEMASN 605
Cdd:pfam03600 39 SPTILLLLGMMIIGAILERTGLFDRLALKLLRLAGGKPRRLLVALM-----LATALLSAFLSNDGTVLIMIPIVLALARR 113
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 62484377 606 DDIPLPPMFWALTFGACFGGNGSLFGAVSNEIIALIALQHGYKISFWHFFAIGFPLMLVTMVIgsgYLLIAHSVLSWN 683
Cdd:pfam03600 114 LGLPPSPLLIALAFAANIGGTATPIGDPPNIIIASALGLSFGDFGFFMFPPVGVALLLVGLLP---LLLIFRKLLPVR 188
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
524-675 |
7.50e-10 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 61.50 E-value: 7.50e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 524 IQWTILLFIAALFVLSEAVDQLGFFEWLGDRTVGFLRSlepQNQIAVTTMVIlwTTALLTIFIDNAAVTIFMLKFSIEMA 603
Cdd:cd00625 37 IDWETILLLFGMMILSAALEETGLFDRLAAKLARASKG---SRRLLLLLMLL--TAALSAFFSNDATAVLLTPIVLALLR 111
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 62484377 604 SNDDIPLPPMFWALTFGACFGGNGSLFGAVSNEIIAlialqHGYKISFWHFFAIGFPLMLVTMVIGSGYLLI 675
Cdd:cd00625 112 KLGLSPPVPLLLALAFAANIGGAATPIGNPPNLIIA-----SLSGLGFLDFLAFMAPPALGLLLLLLGLLYL 178
|
|
| ArsB_NhaD_permease |
cd00625 |
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, ... |
198-394 |
7.96e-09 |
|
Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump.
Pssm-ID: 238344 [Multi-domain] Cd Length: 396 Bit Score: 58.03 E-value: 7.96e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 198 LVCAGLLILGLYMLIIFDVIDHTFAALIIATTAVAILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFL 277
Cdd:cd00625 205 LKKFLLLALLLLLLFVLLFFFLIPLGLIALLGALLLLLLLVRGLDPEEVLKSVDWGTLLFFAGLFVLVGALESTGLLEWL 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 278 VVWTYRISRGRPWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLrtsyvLVVMAIFADMGGALTPLGNPPNA 357
Cdd:cd00625 285 AELLVALVGLPPLAALLLIGLLSALLSNFISNVPTVALLLPIAASLAPPEPA-----WLALALGSTLGGNLTLIGSLANL 359
|
170 180 190
....*....|....*....|....*....|....*..
gi 62484377 358 IVTTSPVAVAEGVDFAHFIIHMMPGVLAAMFVVFGII 394
Cdd:cd00625 360 IPLGAAENAGVGISFGEFLKVGLPLTLLSLVVSLLYL 396
|
|
| CitT |
COG0471 |
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism]; |
203-396 |
1.09e-07 |
|
Di- and tricarboxylate antiporter [Carbohydrate transport and metabolism];
Pssm-ID: 440239 [Multi-domain] Cd Length: 369 Bit Score: 54.39 E-value: 1.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 203 LLILGLYMLIIFDVIDHTFAALIIATtAVAILAILehrpSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTY 282
Cdd:COG0471 182 ALTVLLWITGSLHGIPIAVVALLGAV-LLLLTGVL----TWKDAYKSIPWGVLLLFGGGLALGAALEKTGLAAWLADALL 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 283 RISRGRPWPLIFF-LSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMgGALTPLGNPPNAIVTT 361
Cdd:COG0471 257 PLLGGLSPLLLLLlLALLTLLLTEFASNTATAALLLPIAISLAQALGVNPLPLALAVAFAASC-AFLLPVGTPPNAIVYG 335
|
170 180 190
....*....|....*....|....*....|....*
gi 62484377 362 SpvavaEGVDFAHFIIHMMPGVLAAMFVVFGIIYV 396
Cdd:COG0471 336 S-----GYYKFKDFLKVGLPLNLIGLVVLLLLGPL 365
|
|
| ArsB |
COG1055 |
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism]; |
169-396 |
2.90e-07 |
|
Na+/H+ antiporter NhaD or related arsenite permease [Inorganic ion transport and metabolism];
Pssm-ID: 440675 [Multi-domain] Cd Length: 415 Bit Score: 53.21 E-value: 2.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 169 AVISLESKRNSPISLHVVIDTNPMVTDMCLVCAGLLILGLymlIIFDVIDHTFAAL---IIATTAVAILAILeHRPSMRA 245
Cdd:COG1055 188 LVLYLLFRKELPAAPDLEDDPKEAIKDRRLLRISLLVLAL---LLVGFVLHSFLGLppaLIALLGAAVLLLL-ARVDVRE 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 246 IVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRISRGRPWPLIFFLSMLTAFLSAFLNsdimALSLTPITIRLCE 325
Cdd:COG1055 264 VLKKVDWSTLLFFIGLFVVVGGLENTGLLDLLAELLASLTGGNLLLAALLILWLSAILSAVVD----NVPLVAALLPLIP 339
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 62484377 326 EMSLRTSYVLVVMA--IFADMGGALTPLGNPPNAIVttspVAVAEG----VDFAHFIIHMMPGVLAAMFVVFGIIYV 396
Cdd:COG1055 340 DLGATGNPEPLWLAlaLGATLGGNLTPIGSAANVIV----LGIAEKkgikISFGEFLKVGLPLTLLTLLIALLYLLL 412
|
|
| dass |
TIGR00785 |
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally ... |
204-625 |
9.55e-06 |
|
anion transporter; The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 273267 [Multi-domain] Cd Length: 444 Bit Score: 48.49 E-value: 9.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 204 LILGLYMLIIFDVIDHTFAALIIATTAVAILAIL----EHRPSMRAIVSFVNfEPLMLLFGLMTIVDIMATTGVFDFLVV 279
Cdd:TIGR00785 12 LLLAIFVAAIVGWILEPLPLPVTALLAIPIIAVLlgvlSAFKFKNALSGFAD-PTIWLFFGAFILATALVKTGLGKRIAY 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 280 WTYRISRGRPWPLIFFLSMLTAFLSAFL--NSDIMALSLTPITIRLC------EEMSLRT--SYVLVVMAIFADMGGALT 349
Cdd:TIGR00785 91 KLVGKMGGTTLGLGYFLVFLETLLAPMWpsNTARAGGILLPIIKSLLpllgskPEKSPRKigKYLMLGIAYSASIGSSGF 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 350 PLGNPPNAIVT--TSPVAVAEgVDFAHFIIHMMPGVLAAMFVVFGIIYVTHR-KSIFVLDQNQLDLMEERARGKKPPSQE 426
Cdd:TIGR00785 171 LTGSAPNALAAgiLSKILGIQ-ISWGDWFLAGLPLGIILLLLVPLLLYVLFPpELKLKDEVDLWAKEELEEMGPMSFREK 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 427 TLDRIALLKGSLpgkyWlrpvegypetlaeleassrILDKPLLVRCCIALIFAFLCMLLHSIpkvadgasLGWvtllaaf 506
Cdd:TIGR00785 250 ALLGIFLLALLL----W-------------------IFGGSLGINASVVALLAVVLMLFLGI--------VTW------- 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 507 lliilddkNDLNAtlGIIQWTILLFIAALFVLSEAVDQLGFFEWLGDRTVGFLRSLEPQNQIAVTTMVIlwtTALLTIFI 586
Cdd:TIGR00785 292 --------KDIQK--NKVAWNTLILFGGLIGLAGGLKKSGFIKWFSEKLVGILDGLSPTIAVLVLVVLF---YIILYFFA 358
|
410 420 430
....*....|....*....|....*....|....*....
gi 62484377 587 DNAAVTIFMLKFSIEMASNDDIPLPPMFWALTFGACFGG 625
Cdd:TIGR00785 359 SNTAHTAALVPIFFSVASAQGIPLELLALALALSASLMG 397
|
|
| CitMHS |
pfam03600 |
Citrate transporter; |
205-342 |
5.71e-05 |
|
Citrate transporter;
Pssm-ID: 460985 [Multi-domain] Cd Length: 342 Bit Score: 45.77 E-value: 5.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 205 ILGLYMLIIFDVIDHTFAALIIATTAVAILAILEHRPSMRAIVSFVNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTYRI 284
Cdd:pfam03600 207 LLLAISALVLALVILGFLLLSVLALAGALLLLLTGVLDPEEALKAVDWSTLLFFAGLFILVGALEKTGLADALADALGGL 286
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 62484377 285 SrgRPWPLIFFLSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFA 342
Cdd:pfam03600 287 S--GLLVALALILWLSALLSAFISNVPTAALMAPIIVGMAPAAGLGDPDPLAWALAVG 342
|
|
| PLN00136 |
PLN00136 |
silicon transporter; Provisional |
579-674 |
1.57e-03 |
|
silicon transporter; Provisional
Pssm-ID: 215070 [Multi-domain] Cd Length: 482 Bit Score: 41.52 E-value: 1.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 579 TALLTIFIDNAAVTIFMLKFSIEMASNDDIPLPPMFWALTFGACFGGNGSLFGAVSNEIIALIAlqhgyKISFWHFFAIG 658
Cdd:PLN00136 110 TALASALFTNDTCCVVLTEFVLELAAERNLPAKPFLLALASSANIGSSATPIGNPQNLVIAFNS-----KITFPKFLLGI 184
|
90
....*....|....*.
gi 62484377 659 FPLMLVTMVIGSGYLL 674
Cdd:PLN00136 185 LPAMLAGMAVNMVMLL 200
|
|
| SLC13_permease |
cd01115 |
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been ... |
203-359 |
1.72e-03 |
|
Permease SLC13 (solute carrier 13). The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is related to renal and intestinal Na+/sulfate cotransporters and a few putative bacterial permeases. The SLC13-type proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium and various anions across biological membranes in all three kingdoms of life. A typical ArsB/NhaD permease is composed of 8-13 transmembrane helices.
Pssm-ID: 238535 [Multi-domain] Cd Length: 382 Bit Score: 41.42 E-value: 1.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 62484377 203 LLILGLYMLIIFDVIDHTFAALIIATTAVAILAILEHRPSMRAIVSFvNFEPLMLLFGLMTIVDIMATTGVFDFLVVWTY 282
Cdd:cd01115 193 VLIITIVLLAALAAITGLLPVSVAIAIGAIVLVFGGVLLTKEDYKSI-DWGIIFLFAGGIPLGKALESSGAAALIAEALI 271
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 62484377 283 RISRGRPWPLIFF-LSMLTAFLSAFLNSDIMALSLTPITIRLCEEMSLRTSYVLVVMAIFADMgGALTPLGNPPNAIV 359
Cdd:cd01115 272 SLLGGLPPFAILLlLCLLTLVLTNFISNTATAVLLAPIALSIALSLGLPPEALLLAVAIGASC-AFMLPVGTPPNAIV 348
|
|
| |
