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Conserved domains on  [gi|24584647|ref|NP_723981|]
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miles to go, isoform G [Drosophila melanogaster]

Protein Classification

fibronectin type III domain-containing protein( domain architecture ID 10045852)

fibronectin type III (FN3) domain-containing protein may be involved in specific interactions with other molecules through its FN3 domain

CATH:  2.60.40.10
Gene Ontology:  GO:0005515
PubMed:  19576999|9837732|8981327

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
729-958 9.60e-24

Fibronectin type 3 domain [General function prediction only];


:

Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 107.78  E-value: 9.60e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  729 DLTPGGMYETQVRAINRIGAGSWSQWMRFTAAAAAPGVPEELRVLVKSATHLGVSWQPPlqeNGAPVTSYTLksasqERK 808
Cdd:COG3401  198 DIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTGLTATADTPGSVTLSWDPV---TESDATGYRV-----YRS 269

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  809 EDDSE--EEVKEPPSSEFHNcyqgpqtcaelRNLSPYTRYHFRIQASNSAG-TGNSSDVISVCTPAAVPGAPQ-MQGYEF 884
Cdd:COG3401  270 NSGDGpfTKVATVTTTSYTD-----------TGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPPAAPSgLTATAV 338

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  885 TAQEVTLNWTqpAAHGSPICSYNIEYGE------RTIATPDACTRYTVSGLMPETGYKFRVQAVNAIG-AGAFSAYAKLT 957
Cdd:COG3401  339 GSSSITLSWT--ASSDADVTGYNVYRSTsgggtyTKIAETVTTTSYTDTGLTPGTTYYYKVTAVDAAGnESAPSEEVSAT 416


                 .
gi 24584647  958 T 958
Cdd:COG3401  417 T 417
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 386-473 1.51e-14

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 70.60  E-value: 1.51e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  386 KLVSRTKNSINLRWAAPAANGASIQHYLLEYDEgrMPGQPQKFVELAKIKAKHYVIGKLQPTTVYSFRLAAVNEAGQSPY 465
Cdd:cd00063    8 RVTDVTSTSVTLSWTPPEDDGGPITGYVVEYRE--KGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPP 85


                 ....*...
gi 24584647  466 SPVASYST 473
Cdd:cd00063   86 SESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 968-1063 4.05e-08

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 52.11  E-value: 4.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  968 LECSGAGHNYIKLKWgengngkvvnSNPSGNGGDFTKYFVEMYVARAKQFQAV--YSGTNCMCKVHKLQERSSYTFRIYA 1045
Cdd:cd00063    7 LRVTDVTSTSVTLSW----------TPPEDDGGPITGYVVEYREKGSGDWKEVevTPGSETSYTLTGLKPGTEYEFRVRA 76

                         90
                 ....*....|....*...
gi 24584647 1046 HTDrAGDGDYSEEFVFET 1063
Cdd:cd00063   77 VNG-GGESPPSESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 570-661 2.69e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 49.80  E-value: 2.69e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  570 PGRPGKPHAKGkIHGTQFKARWDAPSDSGGaEILCYHLELSAAGPAFERIYS---GAETEAMCERLQPGTTYALRACCEG 646
Cdd:cd00063    1 PSPPTNLRVTD-VTSTSVTLSWTPPEDDGG-PITGYVVEYREKGSGDWKEVEvtpGSETSYTLTGLKPGTEYEFRVRAVN 78

                         90
                 ....*....|....*
gi 24584647  647 PAGQSPYSDIGHVTT 661
Cdd:cd00063   79 GGGESPPSESVTVTT 93
FN3 super family cl27307
Fibronectin type 3 domain [General function prediction only];
286-474 3.89e-07

Fibronectin type 3 domain [General function prediction only];


The actual alignment was detected with superfamily member COG3401:

Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 54.62  E-value: 3.89e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  286 VIDVTSRAAKIIWeSPAIANTVTvdmrqlRYQVLLCDSGKQcKYKSLYQGEAYECIVQDLQPGQDYLVRLQVHYQklTGT 365
Cdd:COG3401  241 ATADTPGSVTLSW-DPVTESDAT------GYRVYRSNSGDG-PFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDA--AGN 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  366 VSDPTEF---RTPPCEPDQPPPPKLVSRTKNSINLRWAAPAANGASiqHYLLEYDEGrmpgQPQKFVELAK-IKAKHYVI 441
Cdd:COG3401  311 ESAPSNVvsvTTDLTPPAAPSGLTATAVGSSSITLSWTASSDADVT--GYNVYRSTS----GGGTYTKIAEtVTTTSYTD 384

                        170       180       190
                 ....*....|....*....|....*....|....
gi 24584647  442 GKLQPTTVYSFRLAAVNEAG-QSPYSPVASYSTS 474
Cdd:COG3401  385 TGLTPGTTYYYKVTAVDAAGnESAPSEEVSATTA 418
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 683-758 1.65e-05

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 44.79  E-value: 1.65e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24584647  683 ALLKLRPPEYNGGaPILEFEAQMRRLEQVQPPQL-VYRGKQTYFVAQDLTPGGMYETQVRAINRIGAGSWSQWMRFT 758
Cdd:cd00063   17 VTLSWTPPEDDGG-PITGYVVEYREKGSGDWKEVeVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVTVT 92
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 498-565 3.73e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


:

Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.25  E-value: 3.73e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24584647  498 WERRAQDG----DFLLQLQDAETGHGF-LNTYKGTELQTECLQLRRASSYQFRLRSENEAGFSPWSPEVSYRT 565
Cdd:cd00063   21 WTPPEDDGgpitGYVVEYREKGSGDWKeVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
 
Name Accession Description Interval E-value
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
729-958 9.60e-24

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 107.78  E-value: 9.60e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  729 DLTPGGMYETQVRAINRIGAGSWSQWMRFTAAAAAPGVPEELRVLVKSATHLGVSWQPPlqeNGAPVTSYTLksasqERK 808
Cdd:COG3401  198 DIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTGLTATADTPGSVTLSWDPV---TESDATGYRV-----YRS 269

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  809 EDDSE--EEVKEPPSSEFHNcyqgpqtcaelRNLSPYTRYHFRIQASNSAG-TGNSSDVISVCTPAAVPGAPQ-MQGYEF 884
Cdd:COG3401  270 NSGDGpfTKVATVTTTSYTD-----------TGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPPAAPSgLTATAV 338

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  885 TAQEVTLNWTqpAAHGSPICSYNIEYGE------RTIATPDACTRYTVSGLMPETGYKFRVQAVNAIG-AGAFSAYAKLT 957
Cdd:COG3401  339 GSSSITLSWT--ASSDADVTGYNVYRSTsgggtyTKIAETVTTTSYTDTGLTPGTTYYYKVTAVDAAGnESAPSEEVSAT 416


                 .
gi 24584647  958 T 958
Cdd:COG3401  417 T 417
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 764-869 4.66e-16

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 74.84  E-value: 4.66e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  764 PGVPEELRVLVKSATHLGVSWQPPlQENGAPVTSYTLksasqERKEDDSEEEVKEPPSSefhncyqGPQTCAELRNLSPY 843
Cdd:cd00063    1 PSPPTNLRVTDVTSTSVTLSWTPP-EDDGGPITGYVV-----EYREKGSGDWKEVEVTP-------GSETSYTLTGLKPG 67

                         90       100
                 ....*....|....*....|....*.
gi 24584647  844 TRYHFRIQASNSAGTGNSSDVISVCT 869
Cdd:cd00063   68 TEYEFRVRAVNGGGESPPSESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 386-473 1.51e-14

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 70.60  E-value: 1.51e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  386 KLVSRTKNSINLRWAAPAANGASIQHYLLEYDEgrMPGQPQKFVELAKIKAKHYVIGKLQPTTVYSFRLAAVNEAGQSPY 465
Cdd:cd00063    8 RVTDVTSTSVTLSWTPPEDDGGPITGYVVEYRE--KGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPP 85


                 ....*...
gi 24584647  466 SPVASYST 473
Cdd:cd00063   86 SESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 764-859 3.36e-12

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 63.40  E-value: 3.36e-12
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647     764 PGVPEELRVLVKSATHLGVSWQPPLQENG-APVTSYTLksasQERKEDDSEEEVKEPPSsefhncyqgpQTCAELRNLSP 842
Cdd:smart00060    1 PSPPSNLRVTDVTSTSVTLSWEPPPDDGItGYIVGYRV----EYREEGSEWKEVNVTPS----------STSYTLTGLKP 66

                            90
                    ....*....|....*..
gi 24584647     843 YTRYHFRIQASNSAGTG 859
Cdd:smart00060   67 GTEYEFRVRAVNGAGEG 83
fn3 pfam00041
Fibronectin type III domain;
767-862 6.39e-12

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 62.82  E-value: 6.39e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647    767 PEELRVLVKSATHLGVSWQPPLQENGaPVTSYTLksasqERKEDDSEEEVKEppsseFHNCyqGPQTCAELRNLSPYTRY 846
Cdd:pfam00041    3 PSNLTVTDVTSTSLTVSWTPPPDGNG-PITGYEV-----EYRPKNSGEPWNE-----ITVP--GTTTSVTLTGLKPGTEY 69

                           90
                   ....*....|....*.
gi 24584647    847 HFRIQASNSAGTGNSS 862
Cdd:pfam00041   70 EVRVQAVNGGGEGPPS 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 386-463 1.32e-09

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 56.08  E-value: 1.32e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24584647     386 KLVSRTKNSINLRWAAPAANGasIQHYLLEYDEGRMPGQPQKFVELAKIKAKHYVIGKLQPTTVYSFRLAAVNEAGQS 463
Cdd:smart00060    8 RVTDVTSTSVTLSWEPPPDDG--ITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83
fn3 pfam00041
Fibronectin type III domain;
386-466 7.64e-09

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 53.96  E-value: 7.64e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647    386 KLVSRTKNSINLRWAAPAANGASIQHYLLEYDEGRMPGQPQKFVELAkiKAKHYVIGKLQPTTVYSFRLAAVNEAGQSPY 465
Cdd:pfam00041    7 TVTDVTSTSLTVSWTPPPDGNGPITGYEVEYRPKNSGEPWNEITVPG--TTTSVTLTGLKPGTEYEVRVQAVNGGGEGPP 84


                   .
gi 24584647    466 S 466
Cdd:pfam00041   85 S 85
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 968-1063 4.05e-08

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 52.11  E-value: 4.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  968 LECSGAGHNYIKLKWgengngkvvnSNPSGNGGDFTKYFVEMYVARAKQFQAV--YSGTNCMCKVHKLQERSSYTFRIYA 1045
Cdd:cd00063    7 LRVTDVTSTSVTLSW----------TPPEDDGGPITGYVVEYREKGSGDWKEVevTPGSETSYTLTGLKPGTEYEFRVRA 76

                         90
                 ....*....|....*...
gi 24584647 1046 HTDrAGDGDYSEEFVFET 1063
Cdd:cd00063   77 VNG-GGESPPSESVTVTT 93
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
344-470 1.90e-07

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 55.78  E-value: 1.90e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  344 DLQPGQDYLVRLQVHYQKLTGTVSDPTEFRTPPCEPDQPPPPKLVSRTKNSINLRWAAPAANGASiqHYLLEydegRMPG 423
Cdd:COG3401  198 DIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTGLTATADTPGSVTLSWDPVTESDAT--GYRVY----RSNS 271

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 24584647  424 QPQKFVELAKIKAKHYVIGKLQPTTVYSFRLAAVNEAG-QSPYSPVAS 470
Cdd:COG3401  272 GDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVS 319
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 570-661 2.69e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 49.80  E-value: 2.69e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  570 PGRPGKPHAKGkIHGTQFKARWDAPSDSGGaEILCYHLELSAAGPAFERIYS---GAETEAMCERLQPGTTYALRACCEG 646
Cdd:cd00063    1 PSPPTNLRVTD-VTSTSVTLSWTPPEDDGG-PITGYVVEYREKGSGDWKEVEvtpGSETSYTLTGLKPGTEYEFRVRAVN 78

                         90
                 ....*....|....*
gi 24584647  647 PAGQSPYSDIGHVTT 661
Cdd:cd00063   79 GGGESPPSESVTVTT 93
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
286-474 3.89e-07

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 54.62  E-value: 3.89e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  286 VIDVTSRAAKIIWeSPAIANTVTvdmrqlRYQVLLCDSGKQcKYKSLYQGEAYECIVQDLQPGQDYLVRLQVHYQklTGT 365
Cdd:COG3401  241 ATADTPGSVTLSW-DPVTESDAT------GYRVYRSNSGDG-PFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDA--AGN 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  366 VSDPTEF---RTPPCEPDQPPPPKLVSRTKNSINLRWAAPAANGASiqHYLLEYDEGrmpgQPQKFVELAK-IKAKHYVI 441
Cdd:COG3401  311 ESAPSNVvsvTTDLTPPAAPSGLTATAVGSSSITLSWTASSDADVT--GYNVYRSTS----GGGTYTKIAEtVTTTSYTD 384

                        170       180       190
                 ....*....|....*....|....*....|....
gi 24584647  442 GKLQPTTVYSFRLAAVNEAG-QSPYSPVASYSTS 474
Cdd:COG3401  385 TGLTPGTTYYYKVTAVDAAGnESAPSEEVSATTA 418
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 279-374 1.53e-06

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 47.88  E-value: 1.53e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  279 SAIEKPEVIDVTSRAAKIIWESPAIANTvtvdmRQLRYQVLLCDSG----KQCKYKSlyqGEAYECIVQDLQPGQDYLVR 354
Cdd:cd00063    2 SPPTNLRVTDVTSTSVTLSWTPPEDDGG-----PITGYVVEYREKGsgdwKEVEVTP---GSETSYTLTGLKPGTEYEFR 73

                         90       100
                 ....*....|....*....|
gi 24584647  355 LQVHYQKLTGTVSDPTEFRT 374
Cdd:cd00063   74 VRAVNGGGESPPSESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 683-758 1.65e-05

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 44.79  E-value: 1.65e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24584647  683 ALLKLRPPEYNGGaPILEFEAQMRRLEQVQPPQL-VYRGKQTYFVAQDLTPGGMYETQVRAINRIGAGSWSQWMRFT 758
Cdd:cd00063   17 VTLSWTPPEDDGG-PITGYVVEYREKGSGDWKEVeVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVTVT 92
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 570-651 2.19e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 41.45  E-value: 2.19e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647     570 PGRPGKPHAKGkIHGTQFKARWDAPSDSGG-AEILCYHLELSAAGPAFERIY-SGAETEAMCERLQPGTTYALRACCEGP 647
Cdd:smart00060    1 PSPPSNLRVTD-VTSTSVTLSWEPPPDDGItGYIVGYRVEYREEGSEWKEVNvTPSSTSYTLTGLKPGTEYEFRVRAVNG 79


                    ....
gi 24584647     648 AGQS 651
Cdd:smart00060   80 AGEG 83
fn3 pfam00041
Fibronectin type III domain;
279-364 9.05e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 39.71  E-value: 9.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647    279 SAIEKPEVIDVTSRAAKIIWESPAIANtVTVDMRQLRYQVllCDSGKQCKYKSLyQGEAYECIVQDLQPGQDYLVRLQVH 358
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPDGN-GPITGYEVEYRP--KNSGEPWNEITV-PGTTTSVTLTGLKPGTEYEVRVQAV 76


                   ....*.
gi 24584647    359 YQKLTG 364
Cdd:pfam00041   77 NGGGEG 82
fn3 pfam00041
Fibronectin type III domain;
967-1056 2.87e-03

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 38.16  E-value: 2.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647    967 RLECSGAGHNYIKLKWgengngkvvnSNPSGNGGDFTKYFVEMYVARAKQFQAVY--SGTNCMCKVHKLQERSSYTFRIY 1044
Cdd:pfam00041    5 NLTVTDVTSTSLTVSW----------TPPPDGNGPITGYEVEYRPKNSGEPWNEItvPGTTTSVTLTGLKPGTEYEVRVQ 74

                           90
                   ....*....|..
gi 24584647   1045 AHTDrAGDGDYS 1056
Cdd:pfam00041   75 AVNG-GGEGPPS 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 688-749 2.93e-03

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 37.98  E-value: 2.93e-03
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24584647     688 RPPEYNGGAPILEFEAQMRRLEQVQPpQLVYRGKQTYFVAQDLTPGGMYETQVRAINRIGAG 749
Cdd:smart00060   23 PPPDDGITGYIVGYRVEYREEGSEWK-EVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 279-361 3.05e-03

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 37.98  E-value: 3.05e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647     279 SAIEKPEVIDVTSRAAKIIWESPAIANTVTvdmRQLRYQVLLCDSGKQCKyKSLYQGEAYECIVQDLQPGQDYLVRLQVH 358
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEPPPDDGITG---YIVGYRVEYREEGSEWK-EVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77


                    ...
gi 24584647     359 YQK 361
Cdd:smart00060   78 NGA 80
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 498-565 3.73e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.25  E-value: 3.73e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24584647  498 WERRAQDG----DFLLQLQDAETGHGF-LNTYKGTELQTECLQLRRASSYQFRLRSENEAGFSPWSPEVSYRT 565
Cdd:cd00063   21 WTPPEDDGgpitGYVVEYREKGSGDWKeVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 967-1053 5.65e-03

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 37.21  E-value: 5.65e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647     967 RLECSGAGHNYIKLKWGEngngkvvnSNPSGNGGDFTKYFVEMYVARAKQFQAVYSGTNCMCKVHKLQERSSYTFRIYAH 1046
Cdd:smart00060    6 NLRVTDVTSTSVTLSWEP--------PPDDGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77


                    ....*..
gi 24584647    1047 TDrAGDG 1053
Cdd:smart00060   78 NG-AGEG 83
 
Name Accession Description Interval E-value
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
729-958 9.60e-24

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 107.78  E-value: 9.60e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  729 DLTPGGMYETQVRAINRIGAGSWSQWMRFTAAAAAPGVPEELRVLVKSATHLGVSWQPPlqeNGAPVTSYTLksasqERK 808
Cdd:COG3401  198 DIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTGLTATADTPGSVTLSWDPV---TESDATGYRV-----YRS 269

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  809 EDDSE--EEVKEPPSSEFHNcyqgpqtcaelRNLSPYTRYHFRIQASNSAG-TGNSSDVISVCTPAAVPGAPQ-MQGYEF 884
Cdd:COG3401  270 NSGDGpfTKVATVTTTSYTD-----------TGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPPAAPSgLTATAV 338

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  885 TAQEVTLNWTqpAAHGSPICSYNIEYGE------RTIATPDACTRYTVSGLMPETGYKFRVQAVNAIG-AGAFSAYAKLT 957
Cdd:COG3401  339 GSSSITLSWT--ASSDADVTGYNVYRSTsgggtyTKIAETVTTTSYTDTGLTPGTTYYYKVTAVDAAGnESAPSEEVSAT 416


                 .
gi 24584647  958 T 958
Cdd:COG3401  417 T 417
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 764-869 4.66e-16

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 74.84  E-value: 4.66e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  764 PGVPEELRVLVKSATHLGVSWQPPlQENGAPVTSYTLksasqERKEDDSEEEVKEPPSSefhncyqGPQTCAELRNLSPY 843
Cdd:cd00063    1 PSPPTNLRVTDVTSTSVTLSWTPP-EDDGGPITGYVV-----EYREKGSGDWKEVEVTP-------GSETSYTLTGLKPG 67

                         90       100
                 ....*....|....*....|....*.
gi 24584647  844 TRYHFRIQASNSAGTGNSSDVISVCT 869
Cdd:cd00063   68 TEYEFRVRAVNGGGESPPSESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 386-473 1.51e-14

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 70.60  E-value: 1.51e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  386 KLVSRTKNSINLRWAAPAANGASIQHYLLEYDEgrMPGQPQKFVELAKIKAKHYVIGKLQPTTVYSFRLAAVNEAGQSPY 465
Cdd:cd00063    8 RVTDVTSTSVTLSWTPPEDDGGPITGYVVEYRE--KGSGDWKEVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPP 85


                 ....*...
gi 24584647  466 SPVASYST 473
Cdd:cd00063   86 SESVTVTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 874-958 4.89e-14

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 69.06  E-value: 4.89e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  874 PGAPQ-MQGYEFTAQEVTLNWTQPAAHGSPICSYNIEYGERTIATPDAC-------TRYTVSGLMPETGYKFRVQAVNAI 945
Cdd:cd00063    1 PSPPTnLRVTDVTSTSVTLSWTPPEDDGGPITGYVVEYREKGSGDWKEVevtpgseTSYTLTGLKPGTEYEFRVRAVNGG 80

                         90
                 ....*....|...
gi 24584647  946 GAGAFSAYAKLTT 958
Cdd:cd00063   81 GESPPSESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 764-859 3.36e-12

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 63.40  E-value: 3.36e-12
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647     764 PGVPEELRVLVKSATHLGVSWQPPLQENG-APVTSYTLksasQERKEDDSEEEVKEPPSsefhncyqgpQTCAELRNLSP 842
Cdd:smart00060    1 PSPPSNLRVTDVTSTSVTLSWEPPPDDGItGYIVGYRV----EYREEGSEWKEVNVTPS----------STSYTLTGLKP 66

                            90
                    ....*....|....*..
gi 24584647     843 YTRYHFRIQASNSAGTG 859
Cdd:smart00060   67 GTEYEFRVRAVNGAGEG 83
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 874-948 4.13e-12

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 63.40  E-value: 4.13e-12
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647     874 PGAPQ-MQGYEFTAQEVTLNWTQPA--AHGSPICSYNIEYGE-----RTIATPDACTRYTVSGLMPETGYKFRVQAVNAI 945
Cdd:smart00060    1 PSPPSnLRVTDVTSTSVTLSWEPPPddGITGYIVGYRVEYREegsewKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGA 80


                    ...
gi 24584647     946 GAG 948
Cdd:smart00060   81 GEG 83
fn3 pfam00041
Fibronectin type III domain;
767-862 6.39e-12

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 62.82  E-value: 6.39e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647    767 PEELRVLVKSATHLGVSWQPPLQENGaPVTSYTLksasqERKEDDSEEEVKEppsseFHNCyqGPQTCAELRNLSPYTRY 846
Cdd:pfam00041    3 PSNLTVTDVTSTSLTVSWTPPPDGNG-PITGYEV-----EYRPKNSGEPWNE-----ITVP--GTTTSVTLTGLKPGTEY 69

                           90
                   ....*....|....*.
gi 24584647    847 HFRIQASNSAGTGNSS 862
Cdd:pfam00041   70 EVRVQAVNGGGEGPPS 85
fn3 pfam00041
Fibronectin type III domain;
888-951 7.12e-12

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 62.43  E-value: 7.12e-12
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 24584647    888 EVTLNWTQPAAHGSPICSYNIEY-------GERTIATPDACTRYTVSGLMPETGYKFRVQAVNAIGAGAFS 951
Cdd:pfam00041   15 SLTVSWTPPPDGNGPITGYEVEYrpknsgePWNEITVPGTTTSVTLTGLKPGTEYEVRVQAVNGGGEGPPS 85
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
706-954 1.22e-11

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 69.26  E-value: 1.22e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  706 RRLEQVQPPQLVYRGKQTYFVAQDLTPGGMYETQVRAINRIGAGS-WSQWMRFTAAAAAPGVPEELRVLVKSATHLGVSW 784
Cdd:COG3401  268 RSNSGDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGNESaPSNVVSVTTDLTPPAAPSGLTATAVGSSSITLSW 347

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  785 QPPLqenGAPVTSYTLksasqERKE--DDSEEEVKEPPSSEFHncyqgpqtcaELRNLSPYTRYHFRIQASNSAGT-GNS 861
Cdd:COG3401  348 TASS---DADVTGYNV-----YRSTsgGGTYTKIAETVTTTSY----------TDTGLTPGTTYYYKVTAVDAAGNeSAP 409

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  862 SDVISVCTPAAVPGAPQMQGYEFTAQEVTLNWTQPAAHGSPICSYNIEY---GERTIATPDACTRYTV-SGLMPETGYKF 937
Cdd:COG3401  410 SEEVSATTASAASGESLTASVDAVPLTDVAGATAAASAASNPGVSAAVLadgGDTGNAVPFTTTSSTVtATTTDTTTANL 489

                        250
                 ....*....|....*..
gi 24584647  938 RVQAVNAIGAGAFSAYA 954
Cdd:COG3401  490 SVTTGSLVGGSGASSVT 506
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 386-463 1.32e-09

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 56.08  E-value: 1.32e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24584647     386 KLVSRTKNSINLRWAAPAANGasIQHYLLEYDEGRMPGQPQKFVELAKIKAKHYVIGKLQPTTVYSFRLAAVNEAGQS 463
Cdd:smart00060    8 RVTDVTSTSVTLSWEPPPDDG--ITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83
fn3 pfam00041
Fibronectin type III domain;
386-466 7.64e-09

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 53.96  E-value: 7.64e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647    386 KLVSRTKNSINLRWAAPAANGASIQHYLLEYDEGRMPGQPQKFVELAkiKAKHYVIGKLQPTTVYSFRLAAVNEAGQSPY 465
Cdd:pfam00041    7 TVTDVTSTSLTVSWTPPPDGNGPITGYEVEYRPKNSGEPWNEITVPG--TTTSVTLTGLKPGTEYEVRVQAVNGGGEGPP 84


                   .
gi 24584647    466 S 466
Cdd:pfam00041   85 S 85
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 968-1063 4.05e-08

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 52.11  E-value: 4.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  968 LECSGAGHNYIKLKWgengngkvvnSNPSGNGGDFTKYFVEMYVARAKQFQAV--YSGTNCMCKVHKLQERSSYTFRIYA 1045
Cdd:cd00063    7 LRVTDVTSTSVTLSW----------TPPEDDGGPITGYVVEYREKGSGDWKEVevTPGSETSYTLTGLKPGTEYEFRVRA 76

                         90
                 ....*....|....*...
gi 24584647 1046 HTDrAGDGDYSEEFVFET 1063
Cdd:cd00063   77 VNG-GGESPPSESVTVTT 93
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
344-470 1.90e-07

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 55.78  E-value: 1.90e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  344 DLQPGQDYLVRLQVHYQKLTGTVSDPTEFRTPPCEPDQPPPPKLVSRTKNSINLRWAAPAANGASiqHYLLEydegRMPG 423
Cdd:COG3401  198 DIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTGLTATADTPGSVTLSWDPVTESDAT--GYRVY----RSNS 271

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 24584647  424 QPQKFVELAKIKAKHYVIGKLQPTTVYSFRLAAVNEAG-QSPYSPVAS 470
Cdd:COG3401  272 GDGPFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVS 319
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 570-661 2.69e-07

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 49.80  E-value: 2.69e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  570 PGRPGKPHAKGkIHGTQFKARWDAPSDSGGaEILCYHLELSAAGPAFERIYS---GAETEAMCERLQPGTTYALRACCEG 646
Cdd:cd00063    1 PSPPTNLRVTD-VTSTSVTLSWTPPEDDGG-PITGYVVEYREKGSGDWKEVEvtpGSETSYTLTGLKPGTEYEFRVRAVN 78

                         90
                 ....*....|....*
gi 24584647  647 PAGQSPYSDIGHVTT 661
Cdd:cd00063   79 GGGESPPSESVTVTT 93
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
286-474 3.89e-07

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 54.62  E-value: 3.89e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  286 VIDVTSRAAKIIWeSPAIANTVTvdmrqlRYQVLLCDSGKQcKYKSLYQGEAYECIVQDLQPGQDYLVRLQVHYQklTGT 365
Cdd:COG3401  241 ATADTPGSVTLSW-DPVTESDAT------GYRVYRSNSGDG-PFTKVATVTTTSYTDTGLTNGTTYYYRVTAVDA--AGN 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  366 VSDPTEF---RTPPCEPDQPPPPKLVSRTKNSINLRWAAPAANGASiqHYLLEYDEGrmpgQPQKFVELAK-IKAKHYVI 441
Cdd:COG3401  311 ESAPSNVvsvTTDLTPPAAPSGLTATAVGSSSITLSWTASSDADVT--GYNVYRSTS----GGGTYTKIAEtVTTTSYTD 384

                        170       180       190
                 ....*....|....*....|....*....|....
gi 24584647  442 GKLQPTTVYSFRLAAVNEAG-QSPYSPVASYSTS 474
Cdd:COG3401  385 TGLTPGTTYYYKVTAVDAAGnESAPSEEVSATTA 418
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 279-374 1.53e-06

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 47.88  E-value: 1.53e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  279 SAIEKPEVIDVTSRAAKIIWESPAIANTvtvdmRQLRYQVLLCDSG----KQCKYKSlyqGEAYECIVQDLQPGQDYLVR 354
Cdd:cd00063    2 SPPTNLRVTDVTSTSVTLSWTPPEDDGG-----PITGYVVEYREKGsgdwKEVEVTP---GSETSYTLTGLKPGTEYEFR 73

                         90       100
                 ....*....|....*....|
gi 24584647  355 LQVHYQKLTGTVSDPTEFRT 374
Cdd:cd00063   74 VRAVNGGGESPPSESVTVTT 93
FN3 COG3401
Fibronectin type 3 domain [General function prediction only];
839-1201 2.30e-06

Fibronectin type 3 domain [General function prediction only];


Pssm-ID: 442628 [Multi-domain]  Cd Length: 603  Bit Score: 52.31  E-value: 2.30e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  839 NLSPYTRYHFRIQASNSAGTGNSSDVISVCTPAAVPGAPQ-MQGYEFTAQEVTLNWTqpAAHGSPICSYNIEYGE----- 912
Cdd:COG3401  198 DIEPGTTYYYRVAATDTGGESAPSNEVSVTTPTTPPSAPTgLTATADTPGSVTLSWD--PVTESDATGYRVYRSNsgdgp 275

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  913 -RTIATPDAcTRYTVSGLMPETGYKFRVQAVNAIG-AGAFSAYAKLTTQPAPPAPPR-LECSGAGHNYIKLKWgengngk 989
Cdd:COG3401  276 fTKVATVTT-TSYTDTGLTNGTTYYYRVTAVDAAGnESAPSNVVSVTTDLTPPAAPSgLTATAVGSSSITLSW------- 347

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  990 vvnsNPSGnGGDFTKYfvemyvarakqfqavysgtncmckvhklqerssytfRIYahtdRAGDGDYSEEFVFETSATlpa 1069
Cdd:COG3401  348 ----TASS-DADVTGY------------------------------------NVY----RSTSGGGTYTKIAETVTT--- 379

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647 1070 nikpprvvqegsvclmelpgqlgmqltlewqhsknsfndrveyelqyavlgaaelegeslspkgrsssssgssngapinl 1149
Cdd:COG3401      --------------------------------------------------------------------------------

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|..
gi 24584647 1150 pnhdyrqlyrgpeTKFTIDNLAAGTCYQFRVcpvrIAAGGELLYGQPSSPLR 1201
Cdd:COG3401  380 -------------TSYTDTGLTPGTTYYYKV----TAVDAAGNESAPSEEVS 414
COG4733 COG4733
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
782-958 5.51e-06

Phage-related protein, tail protein J [Mobilome: prophages, transposons];


Pssm-ID: 443767 [Multi-domain]  Cd Length: 978  Bit Score: 51.10  E-value: 5.51e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  782 VSWQPPlqengAPVTSYTLksasQERKEDDS--EEEVKEPPSSEFHNCYQGpqtcaelrnlspytRYHFRIQASNSAGTG 859
Cdd:COG4733  556 VSWDAP-----AGAVAYEV----EWRRDDGNwvSVPRTSGTSFEVPGIYAG--------------DYEVRVRAINALGVS 612

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  860 nSSDVISVCTP----AAVPGAPQmqgyEFTAQ----EVTLNWTQPAahGSPICSYNIEYGERT-------IATPDACTRY 924
Cdd:COG4733  613 -SAWAASSETTvtgkTAPPPAPT----GLTATgglgGITLSWSFPV--DADTLRTEIRYSTTGdwasatvAQALYPGNTY 685

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 24584647  925 TVSGLMPETGYKFRVQAVNAIG-AGAFSAYAKLTT 958
Cdd:COG4733  686 TLAGLKAGQTYYYRARAVDRSGnVSAWWVSGQASA 720
Pur_ac_phosph_N pfam16656
Purple acid Phosphatase, N-terminal domain; This domain is found at the N-terminus of Purple ...
 767-869 1.44e-05

Purple acid Phosphatase, N-terminal domain; This domain is found at the N-terminus of Purple acid phosphatase proteins.


Pssm-ID: 465220 [Multi-domain]  Cd Length: 93  Bit Score: 45.09  E-value: 1.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647    767 PEELRV-LVKSATHLGVSWQPPLQENGaPVTSYTLKSASQERKEDDSEEEVKEPpssefhNCYQGPQTCAELRNLSPYTR 845
Cdd:pfam16656    1 PEQVHLsLTGDSTSMTVSWVTPSAVTS-PVVQYGTSSSALTSTATATSSTYTTG------DGGTGYIHRATLTGLEPGTT 73

                           90       100
                   ....*....|....*....|....
gi 24584647    846 YHFRIqasnSAGTGNSSDVISVCT 869
Cdd:pfam16656   74 YYYRV----GDDNGGWSEVYSFTT 93
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 683-758 1.65e-05

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 44.79  E-value: 1.65e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24584647  683 ALLKLRPPEYNGGaPILEFEAQMRRLEQVQPPQL-VYRGKQTYFVAQDLTPGGMYETQVRAINRIGAGSWSQWMRFT 758
Cdd:cd00063   17 VTLSWTPPEDDGG-PITGYVVEYREKGSGDWKEVeVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVTVT 92
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 570-651 2.19e-04

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 41.45  E-value: 2.19e-04
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647     570 PGRPGKPHAKGkIHGTQFKARWDAPSDSGG-AEILCYHLELSAAGPAFERIY-SGAETEAMCERLQPGTTYALRACCEGP 647
Cdd:smart00060    1 PSPPSNLRVTD-VTSTSVTLSWEPPPDDGItGYIVGYRVEYREEGSEWKEVNvTPSSTSYTLTGLKPGTEYEFRVRAVNG 79


                    ....
gi 24584647     648 AGQS 651
Cdd:smart00060   80 AGEG 83
COG3979 COG3979
Chitodextrinase [Carbohydrate transport and metabolism];
885-946 4.93e-04

Chitodextrinase [Carbohydrate transport and metabolism];


Pssm-ID: 443178 [Multi-domain]  Cd Length: 369  Bit Score: 43.99  E-value: 4.93e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24584647  885 TAQEVTLNWTqPAAHGSPICSYNIEYGERTIATPDACTRYTVSGLMPETGYKFRVQAVNAIG 946
Cdd:COG3979   15 TSSSVSLSWD-ASTDNVGVTGYDVYRGGDQVATVTGLTAWTVTGLTPGTEYTFTVGACDAAG 75
fn3 pfam00041
Fibronectin type III domain;
279-364 9.05e-04

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 39.71  E-value: 9.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647    279 SAIEKPEVIDVTSRAAKIIWESPAIANtVTVDMRQLRYQVllCDSGKQCKYKSLyQGEAYECIVQDLQPGQDYLVRLQVH 358
Cdd:pfam00041    1 SAPSNLTVTDVTSTSLTVSWTPPPDGN-GPITGYEVEYRP--KNSGEPWNEITV-PGTTTSVTLTGLKPGTEYEVRVQAV 76


                   ....*.
gi 24584647    359 YQKLTG 364
Cdd:pfam00041   77 NGGGEG 82
fn3 pfam00041
Fibronectin type III domain;
967-1056 2.87e-03

Fibronectin type III domain;


Pssm-ID: 394996 [Multi-domain]  Cd Length: 85  Bit Score: 38.16  E-value: 2.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647    967 RLECSGAGHNYIKLKWgengngkvvnSNPSGNGGDFTKYFVEMYVARAKQFQAVY--SGTNCMCKVHKLQERSSYTFRIY 1044
Cdd:pfam00041    5 NLTVTDVTSTSLTVSW----------TPPPDGNGPITGYEVEYRPKNSGEPWNEItvPGTTTSVTLTGLKPGTEYEVRVQ 74

                           90
                   ....*....|..
gi 24584647   1045 AHTDrAGDGDYS 1056
Cdd:pfam00041   75 AVNG-GGEGPPS 85
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 688-749 2.93e-03

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 37.98  E-value: 2.93e-03
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24584647     688 RPPEYNGGAPILEFEAQMRRLEQVQPpQLVYRGKQTYFVAQDLTPGGMYETQVRAINRIGAG 749
Cdd:smart00060   23 PPPDDGITGYIVGYRVEYREEGSEWK-EVNVTPSSTSYTLTGLKPGTEYEFRVRAVNGAGEG 83
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 279-361 3.05e-03

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 37.98  E-value: 3.05e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647     279 SAIEKPEVIDVTSRAAKIIWESPAIANTVTvdmRQLRYQVLLCDSGKQCKyKSLYQGEAYECIVQDLQPGQDYLVRLQVH 358
Cdd:smart00060    2 SPPSNLRVTDVTSTSVTLSWEPPPDDGITG---YIVGYRVEYREEGSEWK-EVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77


                    ...
gi 24584647     359 YQK 361
Cdd:smart00060   78 NGA 80
FN3 cd00063
Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein ...
 498-565 3.73e-03

Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all animal proteins contain the FN3 repeat; including extracellular and intracellular proteins, membrane spanning cytokine receptors, growth hormone receptors, tyrosine phosphatase receptors, and adhesion molecules. FN3-like domains are also found in bacterial glycosyl hydrolases.


Pssm-ID: 238020 [Multi-domain]  Cd Length: 93  Bit Score: 38.25  E-value: 3.73e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24584647  498 WERRAQDG----DFLLQLQDAETGHGF-LNTYKGTELQTECLQLRRASSYQFRLRSENEAGFSPWSPEVSYRT 565
Cdd:cd00063   21 WTPPEDDGgpitGYVVEYREKGSGDWKeVEVTPGSETSYTLTGLKPGTEYEFRVRAVNGGGESPPSESVTVTT 93
FN3 smart00060
Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, ...
 967-1053 5.65e-03

Fibronectin type 3 domain; One of three types of internal repeat within the plasma protein, fibronectin. The tenth fibronectin type III repeat contains a RGD cell recognition sequence in a flexible loop between 2 strands. Type III modules are present in both extracellular and intracellular proteins.


Pssm-ID: 214495 [Multi-domain]  Cd Length: 83  Bit Score: 37.21  E-value: 5.65e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647     967 RLECSGAGHNYIKLKWGEngngkvvnSNPSGNGGDFTKYFVEMYVARAKQFQAVYSGTNCMCKVHKLQERSSYTFRIYAH 1046
Cdd:smart00060    6 NLRVTDVTSTSVTLSWEP--------PPDDGITGYIVGYRVEYREEGSEWKEVNVTPSSTSYTLTGLKPGTEYEFRVRAV 77


                    ....*..
gi 24584647    1047 TDrAGDG 1053
Cdd:smart00060   78 NG-AGEG 83
COG4733 COG4733
Phage-related protein, tail protein J [Mobilome: prophages, transposons];
585-823 9.96e-03

Phage-related protein, tail protein J [Mobilome: prophages, transposons];


Pssm-ID: 443767 [Multi-domain]  Cd Length: 978  Bit Score: 40.31  E-value: 9.96e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  585 TQFKARWDAPSDSGGaeilcYHLELSAAGPAFERIYSGAETEAMCERLQPGTtYALRACCEGPAG-QSPYSDIGHVTTEA 663
Cdd:COG4733  552 TTLTVSWDAPAGAVA-----YEVEWRRDDGNWVSVPRTSGTSFEVPGIYAGD-YEVRVRAINALGvSSAWAASSETTVTG 625

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  664 VPPSAPPPPHCSDPPSPYAALLKLRPPEyngGAPILEFEaqMRRLEQV---QPPQLVYRGKQTYFVAQDLTPGGMYETQV 740
Cdd:COG4733  626 KTAPPPAPTGLTATGGLGGITLSWSFPV---DADTLRTE--IRYSTTGdwaSATVAQALYPGNTYTLAGLKAGQTYYYRA 700

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24584647  741 RAINRIG-AGSWsqWMRFTAAAAAPGVPEELRVLVKsATHLGvswqPPLQENGAPVTSYTLKSASQERKEDDSEEEVKEP 819
Cdd:COG4733  701 RAVDRSGnVSAW--WVSGQASADAAGILDAITGQIL-ETELG----QELDAIIQNATVAEVVAATVTDVTAQIDTAVLFA 773


                 ....
gi 24584647  820 PSSE 823
Cdd:COG4733  774 GVAT 777
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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