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Conserved domains on  [gi|28573993|ref|NP_722765|]
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apoptosis inducing factor, isoform B [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AIF_C pfam14721
Apoptosis-inducing factor, mitochondrion-associated, C-term; This C-terminal domain appears to ...
 591-721 8.75e-71

Apoptosis-inducing factor, mitochondrion-associated, C-term; This C-terminal domain appears to be a dimerization domain of the mitochondrial apoptosis-inducing factor 1. protein. The domain also appears at the C-terminus of FAD-dependent pyridine nucleotide-disulfide oxidoreductases. Apoptosis inducing factor (AIF) is a bifunctional mitochondrial flavoprotein critical for energy metabolism and induction of caspase-independent apoptosis. On reduction with NADH, AIF undergoes dimerization and forms tight, long-lived FADH2-NAD charge-transfer complexes proposed to be functionally important.


:

Pssm-ID: 464279  Cd Length: 130  Bit Score: 227.14  E-value: 8.75e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993   591 AGENMTGAKKPYQHQSMFWSDLGPEIGYEGIGLVDSSLPTVGVFALPSESATR---VDQLSESSDSDVPEtstsSSQSSK 667
Cdd:pfam14721   1 AGENMTGAGKPYWHQSMFWSDLGPDVGYEAIGIVDSSLPTVGVFAKATEKDTPkavVEESGESIRSESEE----EATASA 76

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 28573993   668 SDAGASQDGVTCDPDEAGNYGKGVIFYLKNDKIVGILLWNLFNRIGLARTIINQ 721
Cdd:pfam14721  77 SAAPSSEDVASEDPSPGEDYGKGVIFYLRDDKVVGIVLWNVFNRMPIARKIIKD 130
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
256-719 2.44e-65

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


:

Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 222.32  E-value: 2.44e-65
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 256 PYLIIGGGTAAFSAFRAIKSNDATAKVLMISNEFRKPYMRPPLSKELwytpnpnedpikdyrfkqwTG--SERSLFFEPD 333
Cdd:COG1251   3 RIVIIGAGMAGVRAAEELRKLDPDGEITVIGAEPHPPYNRPPLSKVL-------------------AGetDEEDLLLRPA 63

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 334 EFFidpedlDDNangGIAVAQGFSVKKVDAQKRIVTLNDGYEISYDECLIATGCAPKNLPMlrdaPPSVLEKVMVYRTPD 413
Cdd:COG1251  64 DFY------EEN---GIDLRLGTRVTAIDRAARTVTLADGETLPYDKLVLATGSRPRVPPI----PGADLPGVFTLRTLD 130

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 414 DFDRLRKLAAEKRSITIVGNGFIGSELACSLAHysrenNGGKVYQVFQENANMSKVLPNYLSRWTTAKMEAQGVCVIPNA 493
Cdd:COG1251 131 DADALRAALAPGKRVVVIGGGLIGLEAAAALRK-----RGLEVTVVERAPRLLPRQLDEEAGALLQRLLEALGVEVRLGT 205

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 494 SIRSAVRDETNLKLELNNGMTLMSDVVVVCVGCTPNTDLAGPSRLEVDRslgGFVVNAELEARR-NLYVAGDASCFFDPL 572
Cdd:COG1251 206 GVTEIEGDDRVTGVRLADGEELPADLVVVAIGVRPNTELARAAGLAVDR---GIVVDDYLRTSDpDIYAAGDCAEHPGPV 282

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 573 LGRRRVEHHDHSVVSGRLAGENMTGAKKPYQH-QSMFWSDLGpeigyeGIGLVdsslpTVGVFALPSESATRVDqlsess 651
Cdd:COG1251 283 YGRRVLELVAPAYEQARVAAANLAGGPAAYEGsVPSTKLKVF------GVDVA-----SAGDAEGDEEVVVRGD------ 345

                       410       420       430       440       450       460
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 28573993 652 dsdvpetstsssqssksdagasqdgvtcdpDEAGNYGKgviFYLKNDKIVGILLWNLFNRIGLARTII 719
Cdd:COG1251 346 ------------------------------PARGVYKK---LVLRDGRLVGAVLVGDTSDAGALRQLI 380
 
Name Accession Description Interval E-value
AIF_C pfam14721
Apoptosis-inducing factor, mitochondrion-associated, C-term; This C-terminal domain appears to ...
 591-721 8.75e-71

Apoptosis-inducing factor, mitochondrion-associated, C-term; This C-terminal domain appears to be a dimerization domain of the mitochondrial apoptosis-inducing factor 1. protein. The domain also appears at the C-terminus of FAD-dependent pyridine nucleotide-disulfide oxidoreductases. Apoptosis inducing factor (AIF) is a bifunctional mitochondrial flavoprotein critical for energy metabolism and induction of caspase-independent apoptosis. On reduction with NADH, AIF undergoes dimerization and forms tight, long-lived FADH2-NAD charge-transfer complexes proposed to be functionally important.


Pssm-ID: 464279  Cd Length: 130  Bit Score: 227.14  E-value: 8.75e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993   591 AGENMTGAKKPYQHQSMFWSDLGPEIGYEGIGLVDSSLPTVGVFALPSESATR---VDQLSESSDSDVPEtstsSSQSSK 667
Cdd:pfam14721   1 AGENMTGAGKPYWHQSMFWSDLGPDVGYEAIGIVDSSLPTVGVFAKATEKDTPkavVEESGESIRSESEE----EATASA 76

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 28573993   668 SDAGASQDGVTCDPDEAGNYGKGVIFYLKNDKIVGILLWNLFNRIGLARTIINQ 721
Cdd:pfam14721  77 SAAPSSEDVASEDPSPGEDYGKGVIFYLRDDKVVGIVLWNVFNRMPIARKIIKD 130
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
256-719 2.44e-65

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 222.32  E-value: 2.44e-65
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 256 PYLIIGGGTAAFSAFRAIKSNDATAKVLMISNEFRKPYMRPPLSKELwytpnpnedpikdyrfkqwTG--SERSLFFEPD 333
Cdd:COG1251   3 RIVIIGAGMAGVRAAEELRKLDPDGEITVIGAEPHPPYNRPPLSKVL-------------------AGetDEEDLLLRPA 63

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 334 EFFidpedlDDNangGIAVAQGFSVKKVDAQKRIVTLNDGYEISYDECLIATGCAPKNLPMlrdaPPSVLEKVMVYRTPD 413
Cdd:COG1251  64 DFY------EEN---GIDLRLGTRVTAIDRAARTVTLADGETLPYDKLVLATGSRPRVPPI----PGADLPGVFTLRTLD 130

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 414 DFDRLRKLAAEKRSITIVGNGFIGSELACSLAHysrenNGGKVYQVFQENANMSKVLPNYLSRWTTAKMEAQGVCVIPNA 493
Cdd:COG1251 131 DADALRAALAPGKRVVVIGGGLIGLEAAAALRK-----RGLEVTVVERAPRLLPRQLDEEAGALLQRLLEALGVEVRLGT 205

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 494 SIRSAVRDETNLKLELNNGMTLMSDVVVVCVGCTPNTDLAGPSRLEVDRslgGFVVNAELEARR-NLYVAGDASCFFDPL 572
Cdd:COG1251 206 GVTEIEGDDRVTGVRLADGEELPADLVVVAIGVRPNTELARAAGLAVDR---GIVVDDYLRTSDpDIYAAGDCAEHPGPV 282

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 573 LGRRRVEHHDHSVVSGRLAGENMTGAKKPYQH-QSMFWSDLGpeigyeGIGLVdsslpTVGVFALPSESATRVDqlsess 651
Cdd:COG1251 283 YGRRVLELVAPAYEQARVAAANLAGGPAAYEGsVPSTKLKVF------GVDVA-----SAGDAEGDEEVVVRGD------ 345

                       410       420       430       440       450       460
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 28573993 652 dsdvpetstsssqssksdagasqdgvtcdpDEAGNYGKgviFYLKNDKIVGILLWNLFNRIGLARTII 719
Cdd:COG1251 346 ------------------------------PARGVYKK---LVLRDGRLVGAVLVGDTSDAGALRQLI 380
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 257-588 4.82e-40

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 149.39  E-value: 4.82e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993   257 YLIIGGGTAAFSAfrAIKSNDATAKVLMISNEFRKPYMRPPLSKELWYTPNPNEDpikdyrfkqwtgserslFFEPDEFF 336
Cdd:pfam07992   3 VVVIGGGPAGLAA--ALTLAQLGGKVTLIEDEGTCPYGGCVLSKALLGAAEAPEI-----------------ASLWADLY 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993   337 IDPEDLDDNANGGIAVAQGFSVKKVDAQKRIVTL-----NDGYEISYDECLIATGCAPKNLPMlrdaPPSVLEKVMVYRT 411
Cdd:pfam07992  64 KRKEEVVKKLNNGIEVLLGTEVVSIDPGAKKVVLeelvdGDGETITYDRLVIATGARPRLPPI----PGVELNVGFLVRT 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993   412 PDDFDRLRKLAAEKRsITIVGNGFIGSELACSLAHYsrennGGKVYqVFQENANMSKVLPNYLSRWTTAKMEAQGVCVIP 491
Cdd:pfam07992 140 LDSAEALRLKLLPKR-VVVVGGGYIGVELAAALAKL-----GKEVT-LIEALDRLLRAFDEEISAALEKALEKNGVEVRL 212

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993   492 NASIRSAVRDETNLKLELNNGMTLMSDVVVVCVGCTPNTDLAGPSRLEVDRsLGGFVVNAELE-ARRNLYVAGDAscffd 570
Cdd:pfam07992 213 GTSVKEIIGDGDGVEVILKDGTEIDADLVVVAIGRRPNTELLEAAGLELDE-RGGIVVDEYLRtSVPGIYAAGDC----- 286

                         330
                  ....*....|....*...
gi 28573993   571 pllGRRRVEHHDHSVVSG 588
Cdd:pfam07992 287 ---RVGGPELAQNAVAQG 301
PRK09754 PRK09754
phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional
 257-611 1.02e-33

phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional


Pssm-ID: 170080 [Multi-domain]  Cd Length: 396  Bit Score: 133.90  E-value: 1.02e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  257 YLIIGGGTAAFSAFRAIKSNDATAKVLMISNEFRKPYMRPPLSKElwYTPNPNEDPikdyrfkqwtgseRSLFfePDEFF 336
Cdd:PRK09754   6 IIIVGGGQAAAMAAASLRQQGFTGELHLFSDERHLPYERPPLSKS--MLLEDSPQL-------------QQVL--PANWW 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  337 IdpedlddnaNGGIAVAQGFSVKKVDAQKRIVTLNDGYEISYDECLIATGCAPKNLPMLrDAppsVLEKVMVYRTPDDFD 416
Cdd:PRK09754  69 Q---------ENNVHLHSGVTIKTLGRDTRELVLTNGESWHWDQLFIATGAAARPLPLL-DA---LGERCFTLRHAGDAA 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  417 RLRKLAAEKRSITIVGNGFIGSELACSLAHYsrennGGKVYQVFQENANMSKVLPNYLSRWTTAKMEAQGVCVIPNASIR 496
Cdd:PRK09754 136 RLREVLQPERSVVIVGAGTIGLELAASATQR-----RCKVTVIELAATVMGRNAPPPVQRYLLQRHQQAGVRILLNNAIE 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  497 SAVRDEtNLKLELNNGMTLMSDVVVVCVGCTPNTDLAGPSRLEVDrslGGFVVNAELE-ARRNLYVAGDASCFFDPLLGR 575
Cdd:PRK09754 211 HVVDGE-KVELTLQSGETLQADVVIYGIGISANDQLAREANLDTA---NGIVIDEACRtCDPAIFAGGDVAITRLDNGAL 286

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 28573993  576 RRVEHHDHSVVSGRLAGENMTGAKKPYQHQSMFWSD 611
Cdd:PRK09754 287 HRCESWENANNQAQIAAAAMLGLPLPLLPPPWFWSD 322
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 338-550 5.68e-15

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 79.10  E-value: 5.68e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993   338 DPEDLDDNANG-----GIAVAQGFSVKKVDAQKRIVTLNDGYEISYDECLIATGCAPKNLPMlrdaPPSVLEKVMVYRTP 412
Cdd:TIGR02374  52 DLDDITLNSKDwyekhGITLYTGETVIQIDTDQKQVITDAGRTLSYDKLILATGSYPFILPI----PGADKKGVYVFRTI 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993   413 DDFDRLRKLAAEKRSITIVGNGFIGSELACSLAHYsrennGGKVYQVFQENANMSKVLPNYLSRWTTAKMEAQGVCVIPN 492
Cdd:TIGR02374 128 EDLDAIMAMAQRFKKAAVIGGGLLGLEAAVGLQNL-----GMDVSVIHHAPGLMAKQLDQTAGRLLQRELEQKGLTFLLE 202

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 28573993   493 ASIRSAVRDETNLKLELNNGMTLMSDVVVVCVGCTPNTDLAGPSRLEVDRslgGFVVN 550
Cdd:TIGR02374 203 KDTVEIVGATKADRIRFKDGSSLEADLIVMAAGIRPNDELAVSAGIKVNR---GIIVN 257
 
Name Accession Description Interval E-value
AIF_C pfam14721
Apoptosis-inducing factor, mitochondrion-associated, C-term; This C-terminal domain appears to ...
 591-721 8.75e-71

Apoptosis-inducing factor, mitochondrion-associated, C-term; This C-terminal domain appears to be a dimerization domain of the mitochondrial apoptosis-inducing factor 1. protein. The domain also appears at the C-terminus of FAD-dependent pyridine nucleotide-disulfide oxidoreductases. Apoptosis inducing factor (AIF) is a bifunctional mitochondrial flavoprotein critical for energy metabolism and induction of caspase-independent apoptosis. On reduction with NADH, AIF undergoes dimerization and forms tight, long-lived FADH2-NAD charge-transfer complexes proposed to be functionally important.


Pssm-ID: 464279  Cd Length: 130  Bit Score: 227.14  E-value: 8.75e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993   591 AGENMTGAKKPYQHQSMFWSDLGPEIGYEGIGLVDSSLPTVGVFALPSESATR---VDQLSESSDSDVPEtstsSSQSSK 667
Cdd:pfam14721   1 AGENMTGAGKPYWHQSMFWSDLGPDVGYEAIGIVDSSLPTVGVFAKATEKDTPkavVEESGESIRSESEE----EATASA 76

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 28573993   668 SDAGASQDGVTCDPDEAGNYGKGVIFYLKNDKIVGILLWNLFNRIGLARTIINQ 721
Cdd:pfam14721  77 SAAPSSEDVASEDPSPGEDYGKGVIFYLRDDKVVGIVLWNVFNRMPIARKIIKD 130
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
256-719 2.44e-65

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 222.32  E-value: 2.44e-65
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 256 PYLIIGGGTAAFSAFRAIKSNDATAKVLMISNEFRKPYMRPPLSKELwytpnpnedpikdyrfkqwTG--SERSLFFEPD 333
Cdd:COG1251   3 RIVIIGAGMAGVRAAEELRKLDPDGEITVIGAEPHPPYNRPPLSKVL-------------------AGetDEEDLLLRPA 63

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 334 EFFidpedlDDNangGIAVAQGFSVKKVDAQKRIVTLNDGYEISYDECLIATGCAPKNLPMlrdaPPSVLEKVMVYRTPD 413
Cdd:COG1251  64 DFY------EEN---GIDLRLGTRVTAIDRAARTVTLADGETLPYDKLVLATGSRPRVPPI----PGADLPGVFTLRTLD 130

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 414 DFDRLRKLAAEKRSITIVGNGFIGSELACSLAHysrenNGGKVYQVFQENANMSKVLPNYLSRWTTAKMEAQGVCVIPNA 493
Cdd:COG1251 131 DADALRAALAPGKRVVVIGGGLIGLEAAAALRK-----RGLEVTVVERAPRLLPRQLDEEAGALLQRLLEALGVEVRLGT 205

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 494 SIRSAVRDETNLKLELNNGMTLMSDVVVVCVGCTPNTDLAGPSRLEVDRslgGFVVNAELEARR-NLYVAGDASCFFDPL 572
Cdd:COG1251 206 GVTEIEGDDRVTGVRLADGEELPADLVVVAIGVRPNTELARAAGLAVDR---GIVVDDYLRTSDpDIYAAGDCAEHPGPV 282

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 573 LGRRRVEHHDHSVVSGRLAGENMTGAKKPYQH-QSMFWSDLGpeigyeGIGLVdsslpTVGVFALPSESATRVDqlsess 651
Cdd:COG1251 283 YGRRVLELVAPAYEQARVAAANLAGGPAAYEGsVPSTKLKVF------GVDVA-----SAGDAEGDEEVVVRGD------ 345

                       410       420       430       440       450       460
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 28573993 652 dsdvpetstsssqssksdagasqdgvtcdpDEAGNYGKgviFYLKNDKIVGILLWNLFNRIGLARTII 719
Cdd:COG1251 346 ------------------------------PARGVYKK---LVLRDGRLVGAVLVGDTSDAGALRQLI 380
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 276-612 7.18e-44

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 160.75  E-value: 7.18e-44
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 276 NDATAKVLMISNEFRKPYMRPPLSKELwytpnpnEDPIKDyrfkqwtgsERSLFFEPDEFFIDPedlddnangGIAVAQG 355
Cdd:COG0446   2 LGPDAEITVIEKGPHHSYQPCGLPYYV-------GGGIKD---------PEDLLVRTPESFERK---------GIDVRTG 56

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 356 FSVKKVDAQKRIVTLNDGYEISYDECLIATGCAPKNLPMlrdaPPSVLEKVMVYRTPDDFDRLRKLAAEK--RSITIVGN 433
Cdd:COG0446  57 TEVTAIDPEAKTVTLRDGETLSYDKLVLATGARPRPPPI----PGLDLPGVFTLRTLDDADALREALKEFkgKRAVVIGG 132

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 434 GFIGSELACSLAHysrenNGGKVYQVFQENANMSKVLPnYLSRWTTAKMEAQGVCVIPNASIrSAVRDETNLKLELNNGM 513
Cdd:COG0446 133 GPIGLELAEALRK-----RGLKVTLVERAPRLLGVLDP-EMAALLEEELREHGVELRLGETV-VAIDGDDKVAVTLTDGE 205

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 514 TLMSDVVVVCVGCTPNTDLAGPSRLEVDRSlGGFVVNAELEAR-RNLYVAGDASCFFDPLLGRR-RVEHHDHSVVSGRLA 591
Cdd:COG0446 206 EIPADLVVVAPGVRPNTELAKDAGLALGER-GWIKVDETLQTSdPDVYAAGDCAEVPHPVTGKTvYIPLASAANKQGRVA 284

                       330       340
                ....*....|....*....|.
gi 28573993 592 GENMTGAKKPYQHQSMFWSDL 612
Cdd:COG0446 285 AENILGGPAPFPGLGTFISKV 305
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 257-588 4.82e-40

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 149.39  E-value: 4.82e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993   257 YLIIGGGTAAFSAfrAIKSNDATAKVLMISNEFRKPYMRPPLSKELWYTPNPNEDpikdyrfkqwtgserslFFEPDEFF 336
Cdd:pfam07992   3 VVVIGGGPAGLAA--ALTLAQLGGKVTLIEDEGTCPYGGCVLSKALLGAAEAPEI-----------------ASLWADLY 63

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993   337 IDPEDLDDNANGGIAVAQGFSVKKVDAQKRIVTL-----NDGYEISYDECLIATGCAPKNLPMlrdaPPSVLEKVMVYRT 411
Cdd:pfam07992  64 KRKEEVVKKLNNGIEVLLGTEVVSIDPGAKKVVLeelvdGDGETITYDRLVIATGARPRLPPI----PGVELNVGFLVRT 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993   412 PDDFDRLRKLAAEKRsITIVGNGFIGSELACSLAHYsrennGGKVYqVFQENANMSKVLPNYLSRWTTAKMEAQGVCVIP 491
Cdd:pfam07992 140 LDSAEALRLKLLPKR-VVVVGGGYIGVELAAALAKL-----GKEVT-LIEALDRLLRAFDEEISAALEKALEKNGVEVRL 212

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993   492 NASIRSAVRDETNLKLELNNGMTLMSDVVVVCVGCTPNTDLAGPSRLEVDRsLGGFVVNAELE-ARRNLYVAGDAscffd 570
Cdd:pfam07992 213 GTSVKEIIGDGDGVEVILKDGTEIDADLVVVAIGRRPNTELLEAAGLELDE-RGGIVVDEYLRtSVPGIYAAGDC----- 286

                         330
                  ....*....|....*...
gi 28573993   571 pllGRRRVEHHDHSVVSG 588
Cdd:pfam07992 287 ---RVGGPELAQNAVAQG 301
PRK09754 PRK09754
phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional
 257-611 1.02e-33

phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional


Pssm-ID: 170080 [Multi-domain]  Cd Length: 396  Bit Score: 133.90  E-value: 1.02e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  257 YLIIGGGTAAFSAFRAIKSNDATAKVLMISNEFRKPYMRPPLSKElwYTPNPNEDPikdyrfkqwtgseRSLFfePDEFF 336
Cdd:PRK09754   6 IIIVGGGQAAAMAAASLRQQGFTGELHLFSDERHLPYERPPLSKS--MLLEDSPQL-------------QQVL--PANWW 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  337 IdpedlddnaNGGIAVAQGFSVKKVDAQKRIVTLNDGYEISYDECLIATGCAPKNLPMLrDAppsVLEKVMVYRTPDDFD 416
Cdd:PRK09754  69 Q---------ENNVHLHSGVTIKTLGRDTRELVLTNGESWHWDQLFIATGAAARPLPLL-DA---LGERCFTLRHAGDAA 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  417 RLRKLAAEKRSITIVGNGFIGSELACSLAHYsrennGGKVYQVFQENANMSKVLPNYLSRWTTAKMEAQGVCVIPNASIR 496
Cdd:PRK09754 136 RLREVLQPERSVVIVGAGTIGLELAASATQR-----RCKVTVIELAATVMGRNAPPPVQRYLLQRHQQAGVRILLNNAIE 210

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  497 SAVRDEtNLKLELNNGMTLMSDVVVVCVGCTPNTDLAGPSRLEVDrslGGFVVNAELE-ARRNLYVAGDASCFFDPLLGR 575
Cdd:PRK09754 211 HVVDGE-KVELTLQSGETLQADVVIYGIGISANDQLAREANLDTA---NGIVIDEACRtCDPAIFAGGDVAITRLDNGAL 286

                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 28573993  576 RRVEHHDHSVVSGRLAGENMTGAKKPYQHQSMFWSD 611
Cdd:PRK09754 287 HRCESWENANNQAQIAAAAMLGLPLPLLPPPWFWSD 322
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
252-571 2.21e-24

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 105.98  E-value: 2.21e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 252 PKHVpyLIIGGGTAAFSAFRAI-KSNDATAKVLMISnefRKPYMrpplskeLWYTPNPnedpikdyrfkQW-TGSerslf 329
Cdd:COG1252   1 MKRI--VIVGGGFAGLEAARRLrKKLGGDAEVTLID---PNPYH-------LFQPLLP-----------EVaAGT----- 52

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 330 FEPDEFFIDPEDLDDNANggIAVAQGfSVKKVDAQKRIVTLNDGYEISYDECLIATGCAPKNLPMlrdapPSVLEKVMVY 409
Cdd:COG1252  53 LSPDDIAIPLRELLRRAG--VRFIQG-EVTGIDPEARTVTLADGRTLSYDYLVIATGSVTNFFGI-----PGLAEHALPL 124

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 410 RTPDDFDRLRK------LAAEKR---SITIVGNGFIGSELACSLAHYSRENNggKVYQVFQENAN------MSKVLPNY- 473
Cdd:COG1252 125 KTLEDALALRErllaafERAERRrllTIVVVGGGPTGVELAGELAELLRKLL--RYPGIDPDKVRitlveaGPRILPGLg 202

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 474 --LSRWTTAKMEAQGVCVIPNASIRSAVRDetnlKLELNNGMTLMSDVVVVCVGCTPNtDLAGPSRLEVDRslGGFV-VN 550
Cdd:COG1252 203 ekLSEAAEKELEKRGVEVHTGTRVTEVDAD----GVTLEDGEEIPADTVIWAAGVKAP-PLLADLGLPTDR--RGRVlVD 275

                       330       340
                ....*....|....*....|...
gi 28573993 551 AELEARR--NLYVAGDASCFFDP 571
Cdd:COG1252 276 PTLQVPGhpNVFAIGDCAAVPDP 298
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 258-600 4.51e-18

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 87.45  E-value: 4.51e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 258 LIIGGGTAAFSAfrAIKSNDATAKVLMIsnEfrkpymRPPL-----------SKELWYTPNPNEDpIKDYRFKQWTGSER 326
Cdd:COG1249   7 VVIGAGPGGYVA--AIRAAQLGLKVALV--E------KGRLggtclnvgcipSKALLHAAEVAHE-ARHAAEFGISAGAP 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 327 SlffepdeffIDPEDLDDNANGGIA-----VAQGFSVKKVD--------AQKRIVTLNDGYEISYDECLIATGCAPKNLP 393
Cdd:COG1249  76 S---------VDWAALMARKDKVVDrlrggVEELLKKNGVDvirgrarfVDPHTVEVTGGETLTADHIVIATGSRPRVPP 146

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 394 MLRDAPPSVLekvmvyrTPDDFDRLRKLaaeKRSITIVGNGFIGSELACSLAHYsrennGGKVYQVfqenANMSKVLPNY 473
Cdd:COG1249 147 IPGLDEVRVL-------TSDEALELEEL---PKSLVVIGGGYIGLEFAQIFARL-----GSEVTLV----ERGDRLLPGE 207

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993 474 ---LSRWTTAKMEAQGVCVIPNASIRSAVRDETNLKLELNNG---MTLMSDVVVVCVGCTPNTDLAGPSRLEVDRSLGGF 547
Cdd:COG1249 208 dpeISEALEKALEKEGIDILTGAKVTSVEKTGDGVTVTLEDGggeEAVEADKVLVATGRRPNTDGLGLEAAGVELDERGG 287

                       330       340       350       360       370
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 28573993 548 V-VNAELE-ARRNLYVAGDAScffdpllGRRRVEH---HDhsvvsGRLAGENMTGAKK 600
Cdd:COG1249 288 IkVDEYLRtSVPGIYAIGDVT-------GGPQLAHvasAE-----GRVAAENILGKKP 333
PRK09564 PRK09564
coenzyme A disulfide reductase; Reviewed
 334-603 1.09e-16

coenzyme A disulfide reductase; Reviewed


Pssm-ID: 181958 [Multi-domain]  Cd Length: 444  Bit Score: 83.17  E-value: 1.09e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  334 EFFIDPEDL-----DDNANGGIAVAQGFSVKKVDAQKRIVTL-----NDGYEISYDECLIATGCAP-----KNLPmlrda 398
Cdd:PRK09564  50 GFFDDPNTMiartpEEFIKSGIDVKTEHEVVKVDAKNKTITVknlktGSIFNDTYDKLMIATGARPiippiKNIN----- 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  399 ppsvLEKVMVYRTPDDFDRLRKLAAEKR--SITIVGNGFIGSELACSLAHYsrenngGKVYQVFQENAnmsKVLPNYLSR 476
Cdd:PRK09564 125 ----LENVYTLKSMEDGLALKELLKDEEikNIVIIGAGFIGLEAVEAAKHL------GKNVRIIQLED---RILPDSFDK 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  477 WTTAKMEA----QGVCVIPNASIRSAVRDETNLKLELNNGmTLMSDVVVVCVGCTPNTDLAGPSRLEVDRSlGGFVVNAE 552
Cdd:PRK09564 192 EITDVMEEelreNGVELHLNEFVKSLIGEDKVEGVVTDKG-EYEADVVIVATGVKPNTEFLEDTGLKTLKN-GAIIVDEY 269

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 28573993  553 LEAR-RNLYVAGDASCFFDPLLGRRrvehhDHSVVS------GRLAGENMTGAKKPYQ 603
Cdd:PRK09564 270 GETSiENIYAAGDCATIYNIVSNKN-----VYVPLAttanklGRMVGENLAGRHVSFK 322
PRK04965 PRK04965
NADH:flavorubredoxin reductase NorW;
256-564 4.13e-16

NADH:flavorubredoxin reductase NorW;


Pssm-ID: 179902 [Multi-domain]  Cd Length: 377  Bit Score: 80.73  E-value: 4.13e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  256 PYLIIGGGTAAFSAFRAIKSNDATAKVLMISNEFRKPYMRPPLSKELWYTPNPnEDPIKDyrfkqwTGSErslFFEPDEF 335
Cdd:PRK04965   4 GIVIIGSGFAARQLVKNIRKQDAHIPITLITADSGDEYNKPDLSHVFSQGQRA-DDLTRQ------SAGE---FAEQFNL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  336 FIDPEDLddnanggiavaqgfsVKKVDAQKRIVTLNDGyEISYDECLIATGCAPKNLPMLRDAPPSVLEKVMVYRTPDDf 415
Cdd:PRK04965  74 RLFPHTW---------------VTDIDAEAQVVKSQGN-QWQYDKLVLATGASAFVPPIPGRELMLTLNSQQEYRAAET- 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  416 drlrKLAAEKRsITIVGNGFIGSELACSLAHysrennGGKVYQVFQENAN-MSKVLPNYLSRWTTAKMEAQGVCVIPNAS 494
Cdd:PRK04965 137 ----QLRDAQR-VLVVGGGLIGTELAMDLCR------AGKAVTLVDNAASlLASLMPPEVSSRLQHRLTEMGVHLLLKSQ 205

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 28573993  495 IRSAVRDETNLKLELNNGMTLMSDVVVVCVGCTPNTDLAGPSRLEVDRslgGFVVNAELE-ARRNLYVAGD 564
Cdd:PRK04965 206 LQGLEKTDSGIRATLDSGRSIEVDAVIAAAGLRPNTALARRAGLAVNR---GIVVDSYLQtSAPDIYALGD 273
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 338-550 5.68e-15

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 79.10  E-value: 5.68e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993   338 DPEDLDDNANG-----GIAVAQGFSVKKVDAQKRIVTLNDGYEISYDECLIATGCAPKNLPMlrdaPPSVLEKVMVYRTP 412
Cdd:TIGR02374  52 DLDDITLNSKDwyekhGITLYTGETVIQIDTDQKQVITDAGRTLSYDKLILATGSYPFILPI----PGADKKGVYVFRTI 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993   413 DDFDRLRKLAAEKRSITIVGNGFIGSELACSLAHYsrennGGKVYQVFQENANMSKVLPNYLSRWTTAKMEAQGVCVIPN 492
Cdd:TIGR02374 128 EDLDAIMAMAQRFKKAAVIGGGLLGLEAAVGLQNL-----GMDVSVIHHAPGLMAKQLDQTAGRLLQRELEQKGLTFLLE 202

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 28573993   493 ASIRSAVRDETNLKLELNNGMTLMSDVVVVCVGCTPNTDLAGPSRLEVDRslgGFVVN 550
Cdd:TIGR02374 203 KDTVEIVGATKADRIRFKDGSSLEADLIVMAAGIRPNDELAVSAGIKVNR---GIIVN 257
PRK07846 PRK07846
mycothione reductase; Reviewed
 363-566 4.39e-09

mycothione reductase; Reviewed


Pssm-ID: 181142 [Multi-domain]  Cd Length: 451  Bit Score: 59.20  E-value: 4.39e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  363 AQKRIVTlNDGYEISYDECLIATGCAPKnlpmlrdAPPSVLEKVMVYRTPDDFDRLRKLAaekRSITIVGNGFIGSELAC 442
Cdd:PRK07846 115 GPKTLRT-GDGEEITADQVVIAAGSRPV-------IPPVIADSGVRYHTSDTIMRLPELP---ESLVIVGGGFIAAEFAH 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  443 SLAHYsrennGGKVYQVfqenaNMSKVLPNYL-----SRWTtaKMEAQGVCVIPNASIRSAVRDETNLKLELNNGMTLMS 517
Cdd:PRK07846 184 VFSAL-----GVRVTVV-----NRSGRLLRHLdddisERFT--ELASKRWDVRLGRNVVGVSQDGSGVTLRLDDGSTVEA 251

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 28573993  518 DVVVVCVGCTPNTDLAGPSRLEVDRSLGGFVVNAELE--ARRNLYVAGDAS 566
Cdd:PRK07846 252 DVLLVATGRVPNGDLLDAAAAGVDVDEDGRVVVDEYQrtSAEGVFALGDVS 302
PRK13748 PRK13748
putative mercuric reductase; Provisional
 347-566 1.49e-08

putative mercuric reductase; Provisional


Pssm-ID: 184298 [Multi-domain]  Cd Length: 561  Bit Score: 57.85  E-value: 1.49e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  347 NGGIAVAQGFSVKKvDAQKRIVTLNDGYE--ISYDECLIATGCAPK--NLPMLRDAPpsvlekvmvYRTPDDfdrlrKLA 422
Cdd:PRK13748 201 NPAITVLHGEARFK-DDQTLIVRLNDGGErvVAFDRCLIATGASPAvpPIPGLKETP---------YWTSTE-----ALV 265

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  423 AEK--RSITIVGNGFIGSELACSLAHYsrennGGKVYQV------FQENANMSKVLpnylsrwtTAKMEAQGVCVIPNAS 494
Cdd:PRK13748 266 SDTipERLAVIGSSVVALELAQAFARL-----GSKVTILarstlfFREDPAIGEAV--------TAAFRAEGIEVLEHTQ 332

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 28573993  495 IRSAVRDETNLKLELNNGmTLMSDVVVVCVGCTPNT-----DLAGpsrLEVDRSlGGFVVNAELEARR-NLYVAGDAS 566
Cdd:PRK13748 333 ASQVAHVDGEFVLTTGHG-ELRADKLLVATGRAPNTrslalDAAG---VTVNAQ-GAIVIDQGMRTSVpHIYAAGDCT 405
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 253-602 2.11e-08

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 57.11  E-value: 2.11e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  253 KHVPYLIIGGGTAAFSAFRAIKsnDATAKVLMISNEfrkPY---------MrpPlSKELWYTPNpnedpikdyRFKQWTG 323
Cdd:PRK06292   2 EKYDVIVIGAGPAGYVAARRAA--KLGKKVALIEKG---PLggtclnvgcI--P-SKALIAAAE---------AFHEAKH 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  324 SErslffepdEFFIDPEDL---------------DDNANGgiAVAQGFSVKKVDAQK---RIV---TLN-DGYEISYDEC 381
Cdd:PRK06292  65 AE--------EFGIHADGPkidfkkvmarvrrerDRFVGG--VVEGLEKKPKIDKIKgtaRFVdpnTVEvNGERIEAKNI 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  382 LIATGCAPKNLPmlrdAPPSVLEKVMVyrTPDDFDRLRKLAaekRSITIVGNGFIGSELACSLAHYsrennGGKVYqVFQ 461
Cdd:PRK06292 135 VIATGSRVPPIP----GVWLILGDRLL--TSDDAFELDKLP---KSLAVIGGGVIGLELGQALSRL-----GVKVT-VFE 199

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  462 ENanmSKVLPNY---LSRWTTAKMEAQgVCVIPNASIRSAVRDETNLKLELNNG---MTLMSDVVVVCVGCTPNTDLAGP 535
Cdd:PRK06292 200 RG---DRILPLEdpeVSKQAQKILSKE-FKIKLGAKVTSVEKSGDEKVEELEKGgktETIEADYVLVATGRRPNTDGLGL 275

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 28573993  536 SRL--EVDRSlgGFV-VNAELE-ARRNLYVAGDASCFFdPLLgrrrvehhdHSVV-SGRLAGENMTGAKKPY 602
Cdd:PRK06292 276 ENTgiELDER--GRPvVDEHTQtSVPGIYAAGDVNGKP-PLL---------HEAAdEGRIAAENAAGDVAGG 335
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 427-512 8.52e-08

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 49.90  E-value: 8.52e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993   427 SITIVGNGFIGSELACSLAHYsrennGGKVYQVfqenANMSKVLPNY---LSRWTTAKMEAQGVCVIPNASIRSAVRDET 503
Cdd:pfam00070   1 RVVVVGGGYIGLELAGALARL-----GSKVTVV----ERRDRLLPGFdpeIAKILQEKLEKNGIEFLLNTTVEAIEGNGD 71


                  ....*....
gi 28573993   504 NLKLELNNG 512
Cdd:pfam00070  72 GVVVVLTDG 80
PRK14989 PRK14989
nitrite reductase subunit NirD; Provisional
 349-550 2.21e-07

nitrite reductase subunit NirD; Provisional


Pssm-ID: 184951 [Multi-domain]  Cd Length: 847  Bit Score: 54.35  E-value: 2.21e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  349 GIAVAQGFSVKKVDAQKRIVTLNDGYEISYDECLIATGCAPKnlpmlrdAPP---SVLEKVMVYRTPDDFDRLRKLAAEK 425
Cdd:PRK14989  73 GIKVLVGERAITINRQEKVIHSSAGRTVFYDKLIMATGSYPW-------IPPikgSETQDCFVYRTIEDLNAIEACARRS 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  426 RSITIVGNGFIGSELACSLAHYSRENNGGKVYQVFqenanMSKVLPNYLSRWTTAKMEAQGVCVIPNASIRSAVRDETNL 505
Cdd:PRK14989 146 KRGAVVGGGLLGLEAAGALKNLGVETHVIEFAPML-----MAEQLDQMGGEQLRRKIESMGVRVHTSKNTLEIVQEGVEA 220

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 28573993  506 K--LELNNGMTLMSDVVVVCVGCTPNTDLAGPSRLEVDRSlGGFVVN 550
Cdd:PRK14989 221 RktMRFADGSELEVDFIVFSTGIRPQDKLATQCGLAVAPR-GGIVIN 266
PRK05249 PRK05249
Si-specific NAD(P)(+) transhydrogenase;
361-598 6.65e-06

Si-specific NAD(P)(+) transhydrogenase;


Pssm-ID: 235373 [Multi-domain]  Cd Length: 461  Bit Score: 49.38  E-value: 6.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  361 VDAQKRIVTLNDG--YEISYDECLIATGCAPknlpmlrdappsvlekvmvYRTPD-DFDRLR--------KLAAEKRSIT 429
Cdd:PRK05249 119 VDPHTVEVECPDGevETLTADKIVIATGSRP-------------------YRPPDvDFDHPRiydsdsilSLDHLPRSLI 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  430 IVGNGFIGSELACSLAhysreNNGGKVYQV--------F--QEnanMSKVLPNYLsrwttakmEAQGVCVIPNASIRSAV 499
Cdd:PRK05249 180 IYGAGVIGCEYASIFA-----ALGVKVTLIntrdrllsFldDE---ISDALSYHL--------RDSGVTIRHNEEVEKVE 243

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  500 RDETNLKLELNNGMTLMSDVVVVCVGCTPNTD-L----AGpsrLEVDrSLGGFVVNAELE-ARRNLYVAGD-------AS 566
Cdd:PRK05249 244 GGDDGVIVHLKSGKKIKADCLLYANGRTGNTDgLnlenAG---LEAD-SRGQLKVNENYQtAVPHIYAVGDvigfpslAS 319

                        250       260       270
                 ....*....|....*....|....*....|..
gi 28573993  567 CFFDpllgrrrvehhdhsvvSGRLAGENMTGA 598
Cdd:PRK05249 320 ASMD----------------QGRIAAQHAVGE 335
PRK06370 PRK06370
FAD-containing oxidoreductase;
372-564 8.24e-06

FAD-containing oxidoreductase;


Pssm-ID: 235787 [Multi-domain]  Cd Length: 463  Bit Score: 49.05  E-value: 8.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  372 DGYEISYDECLIATGCAPK--NLPMLRDAPpsvlekvmvYRTPDDFDRLRKLAaekRSITIVGNGFIGSELACSLAHYsr 449
Cdd:PRK06370 128 GGETLRAKRIFINTGARAAipPIPGLDEVG---------YLTNETIFSLDELP---EHLVIIGGGYIGLEFAQMFRRF-- 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  450 ennGGKVYqVFQ--------ENANMSKVLpnylsrwtTAKMEAQGVCVIPNASIRSAVRDETNLKLELN---NGMTLMSD 518
Cdd:PRK06370 194 ---GSEVT-VIErgprllprEDEDVAAAV--------REILEREGIDVRLNAECIRVERDGDGIAVGLDcngGAPEITGS 261

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 28573993  519 VVVVCVGCTPNTDLAGPSR--LEVDRSlGGFVVNAELEAR-RNLYVAGD 564
Cdd:PRK06370 262 HILVAVGRVPNTDDLGLEAagVETDAR-GYIKVDDQLRTTnPGIYAAGD 309
PRK13512 PRK13512
coenzyme A disulfide reductase; Provisional
 337-565 1.72e-04

coenzyme A disulfide reductase; Provisional


Pssm-ID: 184103 [Multi-domain]  Cd Length: 438  Bit Score: 44.77  E-value: 1.72e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  337 IDPEDLDDNANggIAVAQGFSVKKVDAQKRIVTL-----NDGYEISYDECLIATGCAPKNLPMLRDAppsvlekVMVYRT 411
Cdd:PRK13512  62 YTPEKFYDRKQ--ITVKTYHEVIAINDERQTVTVlnrktNEQFEESYDKLILSPGASANSLGFESDI-------TFTLRN 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  412 PDDFDRLRKLAAE---KRSItIVGNGFIGSELACSLAHYS-------RENNGGKvyqvfQENANMSKVLPNylsrwttaK 481
Cdd:PRK13512 133 LEDTDAIDQFIKAnqvDKAL-VVGAGYISLEVLENLYERGlhptlihRSDKINK-----LMDADMNQPILD--------E 198

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  482 MEAQGVCVIPNASIRSAVRDETNLKlelnNGMTLMSDVVVVCVGCTPNTDLAGPSRLEVDRSlgGFV-VNAELEAR-RNL 559
Cdd:PRK13512 199 LDKREIPYRLNEEIDAINGNEVTFK----SGKVEHYDMIIEGVGTHPNSKFIESSNIKLDDK--GFIpVNDKFETNvPNI 272


                 ....*.
gi 28573993  560 YVAGDA 565
Cdd:PRK13512 273 YAIGDI 278
PRK06416 PRK06416
dihydrolipoamide dehydrogenase; Reviewed
 349-565 3.78e-04

dihydrolipoamide dehydrogenase; Reviewed


Pssm-ID: 235798 [Multi-domain]  Cd Length: 462  Bit Score: 43.60  E-value: 3.78e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  349 GIAVAQGFSvKKVDAQK-RIVTLNDGYEISYDECLIATGCAPKNLPMLrdaPPSvlEKVMVyrTPDD---FDRLRKlaae 424
Cdd:PRK06416 106 KVDIIRGEA-KLVDPNTvRVMTEDGEQTYTAKNIILATGSRPRELPGI---EID--GRVIW--TSDEalnLDEVPK---- 173

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  425 krSITIVGNGFIGSELACSLAhysreNNGGKVYQVfqEnaNMSKVLPNY---LSRWTTAKMEAQGVCVIPNASIRSAVRD 501
Cdd:PRK06416 174 --SLVVIGGGYIGVEFASAYA-----SLGAEVTIV--E--ALPRILPGEdkeISKLAERALKKRGIKIKTGAKAKKVEQT 242

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 28573993  502 ETNLKLELNNGM---TLMSDVVVVCVGCTPNTDLAGPSRL--EVDRslgGFV-VNAELearR----NLYVAGDA 565
Cdd:PRK06416 243 DDGVTVTLEDGGkeeTLEADYVLVAVGRRPNTENLGLEELgvKTDR---GFIeVDEQL---RtnvpNIYAIGDI 310
PTZ00058 PTZ00058
glutathione reductase; Provisional
 370-565 4.31e-03

glutathione reductase; Provisional


Pssm-ID: 185420 [Multi-domain]  Cd Length: 561  Bit Score: 40.37  E-value: 4.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  370 LNDGYEISYDECLIATGcapkNLPMLRDappsvLEKVMVYRTPDDFDRLRklaaEKRSITIVGNGFIGSELACSLAHYSR 449
Cdd:PTZ00058 195 LDDGQVIEGKNILIAVG----NKPIFPD-----VKGKEFTISSDDFFKIK----EAKRIGIAGSGYIAVELINVVNRLGA 261

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28573993  450 EN----NGGKVYQVFQEnaNMSKVLPNylsrwttaKMEAQGVCVIPNASIRSAVRDE-TNLKLELNNGMTLMS-DVVVVC 523
Cdd:PTZ00058 262 ESyifaRGNRLLRKFDE--TIINELEN--------DMKKNNINIITHANVEEIEKVKeKNLTIYLSDGRKYEHfDYVIYC 331

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 28573993  524 VGCTPNTDLAGPSRLEVDRSLGGFVVNA-ELEARRNLYVAGDA 565
Cdd:PTZ00058 332 VGRSPNTEDLNLKALNIKTPKGYIKVDDnQRTSVKHIYAVGDC 374
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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