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Conserved domains on  [gi|24475869|ref|NP_722578|]
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protein CREG2 precursor [Homo sapiens]

Protein Classification

CREG family protein( domain architecture ID 10620712)

CREG (cellular repressor of E1A-stimulated gene) family protein similar to human CREG1 and CREG2, brain-specific secreted glycoproteins that may enhance differentiation of pluripotent stem cells

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Pyrid_oxidase_2 pfam13883
Pyridoxamine 5'-phosphate oxidase;
118-284 2.27e-81

Pyridoxamine 5'-phosphate oxidase;


:

Pssm-ID: 404723  Cd Length: 167  Bit Score: 242.91  E-value: 2.27e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24475869   118 PGPRLRAATARSLAHASVWGCLATVSTHKKIQGLPFGNCLPVSDGPFNNSTGIPFFYMTAKDPVVADLMKNPMASLMLPE 197
Cdd:pfam13883   1 PTREEAAAVARTLVHRESWGTLSTISTVKDIGGAPFGNVVSYSDGPPGDSTGNPYFLLTDLDSTVQNIQKNSRASLTLSE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24475869   198 SEGEFCRKNIVDPEDPRCVQLTLTGQMIAVSPEEVEFAKQAMFSRHPGMRKWPRQYEWFFMKMRIEHIWLQKWYGGASSI 277
Cdd:pfam13883  81 GQTGFCKKHGVDPESPTCARISLTGKLKKVESEEADFAKKALFSRHPDAKYWLPGHNFHFYKLEIEDIYVVGGFGGPAYI 160


                  ....*..
gi 24475869   278 SREEYFK 284
Cdd:pfam13883 161 PAEEYYK 167
 
Name Accession Description Interval E-value
Pyrid_oxidase_2 pfam13883
Pyridoxamine 5'-phosphate oxidase;
118-284 2.27e-81

Pyridoxamine 5'-phosphate oxidase;


Pssm-ID: 404723  Cd Length: 167  Bit Score: 242.91  E-value: 2.27e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24475869   118 PGPRLRAATARSLAHASVWGCLATVSTHKKIQGLPFGNCLPVSDGPFNNSTGIPFFYMTAKDPVVADLMKNPMASLMLPE 197
Cdd:pfam13883   1 PTREEAAAVARTLVHRESWGTLSTISTVKDIGGAPFGNVVSYSDGPPGDSTGNPYFLLTDLDSTVQNIQKNSRASLTLSE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24475869   198 SEGEFCRKNIVDPEDPRCVQLTLTGQMIAVSPEEVEFAKQAMFSRHPGMRKWPRQYEWFFMKMRIEHIWLQKWYGGASSI 277
Cdd:pfam13883  81 GQTGFCKKHGVDPESPTCARISLTGKLKKVESEEADFAKKALFSRHPDAKYWLPGHNFHFYKLEIEDIYVVGGFGGPAYI 160


                  ....*..
gi 24475869   278 SREEYFK 284
Cdd:pfam13883 161 PAEEYYK 167
 
Name Accession Description Interval E-value
Pyrid_oxidase_2 pfam13883
Pyridoxamine 5'-phosphate oxidase;
118-284 2.27e-81

Pyridoxamine 5'-phosphate oxidase;


Pssm-ID: 404723  Cd Length: 167  Bit Score: 242.91  E-value: 2.27e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24475869   118 PGPRLRAATARSLAHASVWGCLATVSTHKKIQGLPFGNCLPVSDGPFNNSTGIPFFYMTAKDPVVADLMKNPMASLMLPE 197
Cdd:pfam13883   1 PTREEAAAVARTLVHRESWGTLSTISTVKDIGGAPFGNVVSYSDGPPGDSTGNPYFLLTDLDSTVQNIQKNSRASLTLSE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24475869   198 SEGEFCRKNIVDPEDPRCVQLTLTGQMIAVSPEEVEFAKQAMFSRHPGMRKWPRQYEWFFMKMRIEHIWLQKWYGGASSI 277
Cdd:pfam13883  81 GQTGFCKKHGVDPESPTCARISLTGKLKKVESEEADFAKKALFSRHPDAKYWLPGHNFHFYKLEIEDIYVVGGFGGPAYI 160


                  ....*..
gi 24475869   278 SREEYFK 284
Cdd:pfam13883 161 PAEEYYK 167
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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