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Conserved domains on  [gi|24649785|ref|NP_651289|]
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uncharacterized protein Dmel_CG6980 [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 117-233 1.60e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 57.70  E-value: 1.60e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649785 117 RAEARAKAEYEAELQRSQGNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEkLQESN 196
Cdd:COG3914 101 YRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALE-LDPDN 179

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 24649785 197 LRAWLYQAHAYKGLKQDDKFEESVVKAREHNPKQLAY 233
Cdd:COG3914 180 AEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 117-233 1.60e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 57.70  E-value: 1.60e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649785 117 RAEARAKAEYEAELQRSQGNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEkLQESN 196
Cdd:COG3914 101 YRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALE-LDPDN 179

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 24649785 197 LRAWLYQAHAYKGLKQDDKFEESVVKAREHNPKQLAY 233
Cdd:COG3914 180 AEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 117-210 1.07e-08

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 55.38  E-value: 1.07e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649785   117 RAEARAKAEYEAELqRSQGNEAFRSQKYEKAILHYDKAIIkVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEkLQESN 196
Cdd:TIGR00990 117 NLSEEERKKYAAKL-KEKGNKAYRNKDFNKAIKLYSKAIE-CKPDPVYYSNRAACHNALGDWEKVVEDTTAALE-LDPDY 193

                          90
                  ....*....|....
gi 24649785   197 LRAWLYQAHAYKGL 210
Cdd:TIGR00990 194 SKALNRRANAYDGL 207
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 133-206 4.07e-03

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 37.84  E-value: 4.07e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24649785  133 SQGNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEkLQESNLRAWLYQAHA 206
Cdd:PLN03088   7 DKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIE-LDPSLAKAYLRKGTA 79
TPR_1 pfam00515
Tetratricopeptide repeat;
162-190 7.98e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 33.16  E-value: 7.98e-03
                          10        20
                  ....*....|....*....|....*....
gi 24649785   162 AITYCNRALCYIKLQNYKRALKDCQYVLE 190
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALE 29
 
Name Accession Description Interval E-value
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 117-233 1.60e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 57.70  E-value: 1.60e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649785 117 RAEARAKAEYEAELQRSQGNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEkLQESN 196
Cdd:COG3914 101 YRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALE-LDPDN 179

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 24649785 197 LRAWLYQAHAYKGLKQDDKFEESVVKAREHNPKQLAY 233
Cdd:COG3914 180 AEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
112-244 3.12e-09

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 55.69  E-value: 3.12e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649785 112 KDANDRAEARAKAEYEAELQRSQGNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEk 191
Cdd:COG4785  57 ALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALE- 135

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 24649785 192 LQESNLRAWLYQAHAYKGLKQDDKFEESVVKAREHNPKQ-LAYIDKYIKQLEAD 244
Cdd:COG4785 136 LDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDpERALWLYLAERKLD 189
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 117-210 1.07e-08

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 55.38  E-value: 1.07e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649785   117 RAEARAKAEYEAELqRSQGNEAFRSQKYEKAILHYDKAIIkVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEkLQESN 196
Cdd:TIGR00990 117 NLSEEERKKYAAKL-KEKGNKAYRNKDFNKAIKLYSKAIE-CKPDPVYYSNRAACHNALGDWEKVVEDTTAALE-LDPDY 193

                          90
                  ....*....|....
gi 24649785   197 LRAWLYQAHAYKGL 210
Cdd:TIGR00990 194 SKALNRRANAYDGL 207
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
127-229 1.55e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 47.69  E-value: 1.55e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649785 127 EAELQRSQGNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEkLQESNLRAWLYQAHA 206
Cdd:COG0457  41 DAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALE-LDPDDAEALYNLGLA 119

                        90       100
                ....*....|....*....|...
gi 24649785 207 YKGLKQDDKFEESVVKAREHNPK 229
Cdd:COG0457 120 LLELGRYDEAIEAYERALELDPD 142
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
127-229 2.59e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 47.31  E-value: 2.59e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649785 127 EAELQRSQGNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEkLQESNLRAWLYQAHA 206
Cdd:COG0457   7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALE-LDPDDAEALNNLGLA 85

                        90       100
                ....*....|....*....|...
gi 24649785 207 YKGLKQDDKFEESVVKAREHNPK 229
Cdd:COG0457  86 LQALGRYEEALEDYDKALELDPD 108
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 116-243 7.38e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 45.88  E-value: 7.38e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649785 116 DRAE-----ARAKAEYEAELQRSQGNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLe 190
Cdd:COG2956  93 DRAEellekLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKAL- 171

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|...
gi 24649785 191 KLQESNLRAWLYQAHAYKGLKQDDKFEESVVKAREHNPKQLAYIDKYIKQLEA 243
Cdd:COG2956 172 KLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEK 224
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 119-230 7.82e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.41  E-value: 7.82e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649785 119 EARAKAEYEAELQRSQGNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLeKLQESNLR 198
Cdd:COG4783  29 KALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKAL-KLDPEHPE 107

                        90       100       110
                ....*....|....*....|....*....|..
gi 24649785 199 AWLYQAHAYKGLKQDDKFEESVVKAREHNPKQ 230
Cdd:COG4783 108 AYLRLARAYRALGRPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 119-249 3.50e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 43.95  E-value: 3.50e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649785 119 EARAKAEYEAELQRSQGNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEkLQESNLR 198
Cdd:COG2956 135 RLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALE-QDPDYLP 213

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|...
gi 24649785 199 AWLYQAHAYKGLKQDDKFEESVVKAREHNPK--QLAYIDKYIKQLEADLKALE 249
Cdd:COG2956 214 ALPRLAELYEKLGDPEEALELLRKALELDPSddLLLALADLLERKEGLEAALA 266
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 75-228 1.20e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.48  E-value: 1.20e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649785  75 RLKVKENRTVINRKSLEEDNEKQVKDMNQKSFMEQVEKDANDRAEARAKAEYEAELQRSQGNEAFRSQKYEKAILHYDKA 154
Cdd:COG5010   1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24649785 155 IIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEkLQESNLRAWLYQAHAYKGLKQDDKFEESVVKAREHNP 228
Cdd:COG5010  81 LQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALA-LSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 116-241 3.27e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.60  E-value: 3.27e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649785 116 DRAEARAKAEYE-AELQRSQGNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEkLQE 194
Cdd:COG4235   4 ARLRQALAANPNdAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALA-LDP 82

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*....
gi 24649785 195 SNLRAWLYQAHAYKGLKQDDKFEESVVKAREHNPK--QLAYIDKYIKQL 241
Cdd:COG4235  83 DNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAdaPARLLEASIAEA 131
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 128-229 7.26e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 38.63  E-value: 7.26e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649785 128 AELQRSQGNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEkLQESNLRAWLYQAHAY 207
Cdd:COG4783   4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALE-LDPDEPEARLNLGLAL 82

                        90       100
                ....*....|....*....|..
gi 24649785 208 KGLKQDDKFEESVVKAREHNPK 229
Cdd:COG4783  83 LKAGDYDEALALLEKALKLDPE 104
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 133-206 4.07e-03

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 37.84  E-value: 4.07e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24649785  133 SQGNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEkLQESNLRAWLYQAHA 206
Cdd:PLN03088   7 DKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIE-LDPSLAKAYLRKGTA 79
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
119-250 4.87e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 37.29  E-value: 4.87e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649785 119 EARAKAEYEAELQRSQGNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQYVLEKLQESNLR 198
Cdd:COG0457 101 KALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLA 180

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|..
gi 24649785 199 AWLYQAHAYKGLKQDDKFEESVVKAREHNPKQLAYIDKYIKQLEADLKALEI 250
Cdd:COG0457 181 AALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLA 232
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 119-229 7.39e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 37.02  E-value: 7.39e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24649785 119 EARAKAEYEAELQRSQGNEAFRSQKYEKAILHYDKAIIKVKDSAITYCNRALCYIKLQNYKRALKDCQyVLEKLQESNLR 198
Cdd:COG2956  67 KLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLE-RLLKLGPENAH 145

                        90       100       110
                ....*....|....*....|....*....|.
gi 24649785 199 AWLYQAHAYKGLKQDDKFEESVVKAREHNPK 229
Cdd:COG2956 146 AYCELAELYLEQGDYDEAIEALEKALKLDPD 176
TPR_1 pfam00515
Tetratricopeptide repeat;
162-190 7.98e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 33.16  E-value: 7.98e-03
                          10        20
                  ....*....|....*....|....*....
gi 24649785   162 AITYCNRALCYIKLQNYKRALKDCQYVLE 190
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALE 29
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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