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Conserved domains on  [gi|21358045|ref|NP_650306|]
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flyers-cup, isoform B [Drosophila melanogaster]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
58-385 1.07e-38

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 148.16  E-value: 1.07e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  58 ELWKLARKSGTLNLSNKALARVPKRLYDINEADADSKAVNLEQLTIKEEDAWWNQVPLNNLDLSSNTLTHISpKIENLQS 137
Cdd:COG4886  19 ELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLT-DLGDLTN 97

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 138 LTVLTLHDNalvelpPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEFVELNPDISDLHMLEFLDGGHNNI 217
Cdd:COG4886  98 LTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQL 171

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 218 QSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLLRKLDCLYLQHNDILELPEFEGNEA 297
Cdd:COG4886 172 TDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTN 251

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 298 LNELHASNNFIKIIPKamCSNLPHLKILDLRDNKITELPDELCLLRNLNRLDVSNNTISVLPVTLSSLAHLISLQVEGNP 377
Cdd:COG4886 252 LEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLL 329


                ....*...
gi 21358045 378 IKTIRRDI 385
Cdd:COG4886 330 LKGLLVTL 337
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
477-626 2.64e-14

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 75.36  E-value: 2.64e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 477 VVDFARNQLSTLPNGLQHMKDLvTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLNDLPTEFGVLNTLRELNIANNRFP 556
Cdd:COG4886 117 SLDLSGNQLTDLPEELANLTNL-KELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQIT 195

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 557 CIPNCVYELQGLEILIASENHIKMLNVSgLQNMRRLSTLDLRNNDIETVPpILGNLTNITHLELVGNPFR 626
Cdd:COG4886 196 DLPEPLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLT 263
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
58-385 1.07e-38

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 148.16  E-value: 1.07e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  58 ELWKLARKSGTLNLSNKALARVPKRLYDINEADADSKAVNLEQLTIKEEDAWWNQVPLNNLDLSSNTLTHISpKIENLQS 137
Cdd:COG4886  19 ELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLT-DLGDLTN 97

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 138 LTVLTLHDNalvelpPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEFVELNPDISDLHMLEFLDGGHNNI 217
Cdd:COG4886  98 LTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQL 171

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 218 QSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLLRKLDCLYLQHNDILELPEFEGNEA 297
Cdd:COG4886 172 TDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTN 251

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 298 LNELHASNNFIKIIPKamCSNLPHLKILDLRDNKITELPDELCLLRNLNRLDVSNNTISVLPVTLSSLAHLISLQVEGNP 377
Cdd:COG4886 252 LEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLL 329


                ....*...
gi 21358045 378 IKTIRRDI 385
Cdd:COG4886 330 LKGLLVTL 337
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 115-555 1.27e-18

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 90.68  E-value: 1.27e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  115 LNNLDLSSNTLT-HISPKIENLQSLTVLTLHDNALV-ELPPEIGKLEKLVRLNVSHNKLS-QLPRAMYSLPELRHLNISY 191
Cdd:PLN00113 142 LETLDLSNNMLSgEIPNDIGSFSSLKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLVgQIPRELGQMKSLKWIYLGY 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  192 NEfvelnpdisdlhmlefLDGGhnniqsLPGGIGFLVRLTALLLPYNHIK-ELPPDLVNMRSLQKIDLMHNDLT-SLPED 269
Cdd:PLN00113 222 NN----------------LSGE------IPYEIGGLTSLNHLDLVYNNLTgPIPSSLGNLKNLQYLFLYQNKLSgPIPPS 279

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  270 MGLLRKLDCLYLQHNDIL-ELPEFEGN-EALNELHA-SNNFIKIIPKAMCSnLPHLKILDLRDNKIT-ELPDELCLLRNL 345
Cdd:PLN00113 280 IFSLQKLISLDLSDNSLSgEIPELVIQlQNLEILHLfSNNFTGKIPVALTS-LPRLQVLQLWSNKFSgEIPKNLGKHNNL 358

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  346 NRLDVSNNTIS-VLPVTLSSLAHLISLQVEGNPIKT-IRRDILQCGTTRILKtLHDRAVAKAKEEGGGVDDASTSAGISV 423
Cdd:PLN00113 359 TVLDLSTNNLTgEIPEGLCSSGNLFKLILFSNSLEGeIPKSLGACRSLRRVR-LQDNSFSGELPSEFTKLPLVYFLDISN 437

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  424 TRLRGgQMDDG--DIP-------------GNFPDRYKLRHTRTLAVNLEELT-SVPDQVFQIARdegVHVVDFARNQLS- 486
Cdd:PLN00113 438 NNLQG-RINSRkwDMPslqmlslarnkffGGLPDSFGSKRLENLDLSRNQFSgAVPRKLGSLSE---LMQLKLSENKLSg 513

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  487 TLPNGLQHMKDLVTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLN-DLPTEFGVLNTLRELNIANNRF 555
Cdd:PLN00113 514 EIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSgEIPKNLGNVESLVQVNISHNHL 583
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
477-626 2.64e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 75.36  E-value: 2.64e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 477 VVDFARNQLSTLPNGLQHMKDLvTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLNDLPTEFGVLNTLRELNIANNRFP 556
Cdd:COG4886 117 SLDLSGNQLTDLPEELANLTNL-KELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQIT 195

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 557 CIPNCVYELQGLEILIASENHIKMLNVSgLQNMRRLSTLDLRNNDIETVPpILGNLTNITHLELVGNPFR 626
Cdd:COG4886 196 DLPEPLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLT 263
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 229-383 3.29e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 66.35  E-value: 3.29e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 229 RLTALLLPYNHIKELPpDLVNMRSLQKIDLMHNDLTSLpEDMGLLRKLDCLYLQHNDILELPEFEGNEALNELHASNNFI 308
Cdd:cd21340   3 RITHLYLNDKNITKID-NLSLCKNLKVLYLYDNKITKI-ENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRI 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 309 KII----------------------------PKAMCSNLPHLKILDLRDNKITELpDELCLLRNLNRLDVSNNTIS---V 357
Cdd:cd21340  81 SVVeglenltnleelhienqrlppgekltfdPRSLAALSNSLRVLNISGNNIDSL-EPLAPLRNLEQLDASNNQISdleE 159

                       170       180
                ....*....|....*....|....*.
gi 21358045 358 LPVTLSSLAHLISLQVEGNPIKTIRR 383
Cdd:cd21340 160 LLDLLSSWPSLRELDLTGNPVCKKPK 185
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 542-625 7.23e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 50.55  E-value: 7.23e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 542 LNTLRELNIANNRFP-----CI-PNCVYELQG-LEILIASENHIKmlNVSGLQNMRRLSTLDLRNN---DIETVPPILGN 611
Cdd:cd21340  89 LTNLEELHIENQRLPpgeklTFdPRSLAALSNsLRVLNISGNNID--SLEPLAPLRNLEQLDASNNqisDLEELLDLLSS 166

                        90
                ....*....|....
gi 21358045 612 LTNITHLELVGNPF 625
Cdd:cd21340 167 WPSLRELDLTGNPV 180
LRR_8 pfam13855
Leucine rich repeat;
115-171 4.16e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 44.44  E-value: 4.16e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 21358045   115 LNNLDLSSNTLTHISPKI-ENLQSLTVLTLHDNALVELPPE-IGKLEKLVRLNVSHNKL 171
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
566-625 2.90e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.43  E-value: 2.90e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 21358045   566 QGLEILIASENHIKMLNVSGLQNMRRLSTLDLRNNDIETVPPI-LGNLTNITHLELVGNPF 625
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
450-650 9.27e-04

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 42.38  E-value: 9.27e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  450 RTLAVNLEELTSVPDQVfqiarDEGVHVVDFARNQLSTLPnglQHMKDLVTELVLSNNVIGYVPQfisqftrisflnlsn 529
Cdd:PRK15370 265 QSLDLFHNKISCLPENL-----PEELRYLSVYDNSIRTLP---AHLPSGITHLNVQSNSLTALPE--------------- 321

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  530 nllndlptefgvlntlrelniannrfpCIPncvyelQGLEILIASENHIKMLNVS---GLQNmrrlstLDLRNNDI---- 602
Cdd:PRK15370 322 ---------------------------TLP------PGLKTLEAGENALTSLPASlppELQV------LDVSKNQItvlp 362

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 21358045  603 ETVPPILGNLtNITHLELVGNPFRQPRHQILMKGTDAIMSYLRDRIPT 650
Cdd:PRK15370 363 ETLPPTITTL-DVSRNALTNLPENLPAALQIMQASRNNLVRLPESLPH 409
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
58-385 1.07e-38

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 148.16  E-value: 1.07e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  58 ELWKLARKSGTLNLSNKALARVPKRLYDINEADADSKAVNLEQLTIKEEDAWWNQVPLNNLDLSSNTLTHISpKIENLQS 137
Cdd:COG4886  19 ELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLT-DLGDLTN 97

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 138 LTVLTLHDNalvelpPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEFVELNPDISDLHMLEFLDGGHNNI 217
Cdd:COG4886  98 LTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQL 171

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 218 QSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLLRKLDCLYLQHNDILELPEFEGNEA 297
Cdd:COG4886 172 TDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTN 251

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 298 LNELHASNNFIKIIPKamCSNLPHLKILDLRDNKITELPDELCLLRNLNRLDVSNNTISVLPVTLSSLAHLISLQVEGNP 377
Cdd:COG4886 252 LEELDLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLL 329


                ....*...
gi 21358045 378 IKTIRRDI 385
Cdd:COG4886 330 LKGLLVTL 337
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
45-371 1.47e-34

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 136.22  E-value: 1.47e-34
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  45 ERSTHEDDQVLTQELWKLARKSGTLNLSNKALARVPKRLYDINEADADSKAVNLEQLTIKEEDAWWNQVPLNNLDLSSNT 124
Cdd:COG4886  45 LLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQ 124

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 125 LTHISPKIENLQSLTVLTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEFVELNPDISDL 204
Cdd:COG4886 125 LTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNL 204

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 205 HMLEFLDGGHNNIQSLPGGIGFLVRLTALLLPYNHIKELpPDLVNMRSLQKIDLMHNDLTSLPEDMGlLRKLDCLYLQHN 284
Cdd:COG4886 205 TNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDL-PELGNLTNLEELDLSNNQLTDLPPLAN-LTNLKTLDLSNN 282

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 285 DI-------LELPEFEGNEALNELHASNNFIKIIPKAMCSNLPHLKILDLRDNKITELPDELCLLRNLNRLDVSNNTISV 357
Cdd:COG4886 283 QLtdlklkeLELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLL 362

                       330
                ....*....|....
gi 21358045 358 LPVTLSSLAHLISL 371
Cdd:COG4886 363 LTLLLTLGLLGLLE 376
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
115-381 7.71e-25

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 107.71  E-value: 7.71e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 115 LNNLDLSSNTLTHISPKIENLQSLTVLTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEF 194
Cdd:COG4886   6 LSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLL 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 195 VELNPDISDLHMLEFLDGGHNNiqslpgGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLLR 274
Cdd:COG4886  86 LLGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLT 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 275 KLDCLYLQHNDILELP-EFEGNEALNELHASNNFIKIIPKAMcSNLPHLKILDLRDNKITELPDELCLLRNLNRLDVSNN 353
Cdd:COG4886 160 NLKSLDLSNNQLTDLPeELGNLTNLKELDLSNNQITDLPEPL-GNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNN 238

                       250       260
                ....*....|....*....|....*...
gi 21358045 354 TISVLPVtLSSLAHLISLQVEGNPIKTI 381
Cdd:COG4886 239 QLTDLPE-LGNLTNLEELDLSNNQLTDL 265
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 115-555 1.27e-18

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 90.68  E-value: 1.27e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  115 LNNLDLSSNTLT-HISPKIENLQSLTVLTLHDNALV-ELPPEIGKLEKLVRLNVSHNKLS-QLPRAMYSLPELRHLNISY 191
Cdd:PLN00113 142 LETLDLSNNMLSgEIPNDIGSFSSLKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLVgQIPRELGQMKSLKWIYLGY 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  192 NEfvelnpdisdlhmlefLDGGhnniqsLPGGIGFLVRLTALLLPYNHIK-ELPPDLVNMRSLQKIDLMHNDLT-SLPED 269
Cdd:PLN00113 222 NN----------------LSGE------IPYEIGGLTSLNHLDLVYNNLTgPIPSSLGNLKNLQYLFLYQNKLSgPIPPS 279

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  270 MGLLRKLDCLYLQHNDIL-ELPEFEGN-EALNELHA-SNNFIKIIPKAMCSnLPHLKILDLRDNKIT-ELPDELCLLRNL 345
Cdd:PLN00113 280 IFSLQKLISLDLSDNSLSgEIPELVIQlQNLEILHLfSNNFTGKIPVALTS-LPRLQVLQLWSNKFSgEIPKNLGKHNNL 358

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  346 NRLDVSNNTIS-VLPVTLSSLAHLISLQVEGNPIKT-IRRDILQCGTTRILKtLHDRAVAKAKEEGGGVDDASTSAGISV 423
Cdd:PLN00113 359 TVLDLSTNNLTgEIPEGLCSSGNLFKLILFSNSLEGeIPKSLGACRSLRRVR-LQDNSFSGELPSEFTKLPLVYFLDISN 437

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  424 TRLRGgQMDDG--DIP-------------GNFPDRYKLRHTRTLAVNLEELT-SVPDQVFQIARdegVHVVDFARNQLS- 486
Cdd:PLN00113 438 NNLQG-RINSRkwDMPslqmlslarnkffGGLPDSFGSKRLENLDLSRNQFSgAVPRKLGSLSE---LMQLKLSENKLSg 513

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  487 TLPNGLQHMKDLVTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLN-DLPTEFGVLNTLRELNIANNRF 555
Cdd:PLN00113 514 EIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSgEIPKNLGNVESLVQVNISHNHL 583
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 110-623 4.44e-15

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 79.12  E-value: 4.44e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  110 WNQVPLNN------LDLSSNTLT-HISPKIENLQSLTVLTLHDNALV-ELPPEIGKLEKLVR-LNVSHNKLS-QLPRAmy 179
Cdd:PLN00113  60 WQGITCNNssrvvsIDLSGKNISgKISSAIFRLPYIQTINLSNNQLSgPIPDDIFTTSSSLRyLNLSNNNFTgSIPRG-- 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  180 SLPELRHLNISYNEFV-ELNPDISDLHMLEFLD-GGHNNIQSLPGGIGFLVRLTALLLPYNH-IKELPPDLVNMRSLQKI 256
Cdd:PLN00113 138 SIPNLETLDLSNNMLSgEIPNDIGSFSSLKVLDlGGNVLVGKIPNSLTNLTSLEFLTLASNQlVGQIPRELGQMKSLKWI 217

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  257 DLMHNDLT-SLPEDMGLLRKLDCLYLQHNDIL-ELPEFEGNeaLNELH----ASNNFIKIIPKAMCSnLPHLKILDLRDN 330
Cdd:PLN00113 218 YLGYNNLSgEIPYEIGGLTSLNHLDLVYNNLTgPIPSSLGN--LKNLQylflYQNKLSGPIPPSIFS-LQKLISLDLSDN 294

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  331 KIT-ELPDELCLLRNLNRLDV-SNNTISVLPVTLSSLAHLISLQVEGNpiktirrdilqcgttrilktlhdravakakee 408
Cdd:PLN00113 295 SLSgEIPELVIQLQNLEILHLfSNNFTGKIPVALTSLPRLQVLQLWSN-------------------------------- 342

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  409 gggvddastsagisvtRLRGGqmddgdIPGNFPDRYKLRhtrtlavnleeltsvpdqvfqiardegvhVVDFARNQLS-T 487
Cdd:PLN00113 343 ----------------KFSGE------IPKNLGKHNNLT-----------------------------VLDLSTNNLTgE 371

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  488 LPNGLQHMKDLVTELVLSNNVIGYVPQFIS---QFTRISFLNLSNNLLndLPTEFGVLNTLRELNIANNRFPC-IPNCVY 563
Cdd:PLN00113 372 IPEGLCSSGNLFKLILFSNSLEGEIPKSLGacrSLRRVRLQDNSFSGE--LPSEFTKLPLVYFLDISNNNLQGrINSRKW 449

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 21358045  564 ELQGLEILIASENHIkMLNVSGLQNMRRLSTLDLRNNDI-ETVPPILGNLTNITHLELVGN 623
Cdd:PLN00113 450 DMPSLQMLSLARNKF-FGGLPDSFGSKRLENLDLSRNQFsGAVPRKLGSLSELMQLKLSEN 509
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
477-626 2.64e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 75.36  E-value: 2.64e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 477 VVDFARNQLSTLPNGLQHMKDLvTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLNDLPTEFGVLNTLRELNIANNRFP 556
Cdd:COG4886 117 SLDLSGNQLTDLPEELANLTNL-KELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQIT 195

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 557 CIPNCVYELQGLEILIASENHIKMLNVSgLQNMRRLSTLDLRNNDIETVPpILGNLTNITHLELVGNPFR 626
Cdd:COG4886 196 DLPEPLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLT 263
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
187-388 3.15e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 74.97  E-value: 3.15e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 187 LNISYNEFVELNPDISDLHMLEFLDGGHNNIQSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNdltsl 266
Cdd:COG4886  32 LLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN----- 106

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 267 pEDMGLLRKLDCLYLQHNDILELP-EFEGNEALNELHASNNFIKIIPKAMcSNLPHLKILDLRDNKITELPDELCLLRNL 345
Cdd:COG4886 107 -EELSNLTNLESLDLSGNQLTDLPeELANLTNLKELDLSNNQLTDLPEPL-GNLTNLKSLDLSNNQLTDLPEELGNLTNL 184

                       170       180       190       200
                ....*....|....*....|....*....|....*....|...
gi 21358045 346 NRLDVSNNTISVLPVTLSSLAHLISLQVEGNPIKTIRRDILQC 388
Cdd:COG4886 185 KELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANL 227
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
489-626 5.12e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 71.50  E-value: 5.12e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 489 PNGLQHMKDLvTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLNDLPTEFGVLNTLRELNIANNRFPCIPNCVYELQGL 568
Cdd:COG4886 106 NEELSNLTNL-ESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNL 184

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 21358045 569 EILIASENHIKMLNVSgLQNMRRLSTLDLRNNDIETVPPILGNLTNITHLELVGNPFR 626
Cdd:COG4886 185 KELDLSNNQITDLPEP-LGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLT 241
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
115-312 1.28e-12

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 69.96  E-value: 1.28e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 115 LNNLDLSSNTLTHISPKIENLQSLTVLTLHDNALVELPpEIGKLEKLVRLNVSHNKLSQLPrAMYSLPELRHLNISYNEF 194
Cdd:COG4886 207 LEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLP-PLANLTNLKTLDLSNNQL 284

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 195 VELNPD-ISDLHMLEFLDGGHNNIQSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLL 273
Cdd:COG4886 285 TDLKLKeLELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLT 364

                       170       180       190
                ....*....|....*....|....*....|....*....
gi 21358045 274 RKLDCLYLQHNDILELPEFEGNEALNELHASNNFIKIIP 312
Cdd:COG4886 365 LLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLL 403
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 72-306 2.79e-12

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 70.26  E-value: 2.79e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045   72 SNKALARVPKRLYDINEADADSKAVNleQLTIKEEDAWWNQVPLNNLDLSSNTL-THISPKIENLQSLTVLTLHDNALV- 149
Cdd:PLN00113 341 SNKFSGEIPKNLGKHNNLTVLDLSTN--NLTGEIPEGLCSSGNLFKLILFSNSLeGEIPKSLGACRSLRRVRLQDNSFSg 418

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  150 ELPPEIGKLEKLVRLNVSHNKLS-QLPRAMYSLPELRHLNISYNEFVELNPDISDLHMLEFLDGGHNNIQ-SLPGGIGFL 227
Cdd:PLN00113 419 ELPSEFTKLPLVYFLDISNNNLQgRINSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSgAVPRKLGSL 498

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  228 VRLTALLLPYNHIK-ELPPDLVNMRSLQKIDLMHNDLT-SLP---EDMGLLRKLDclyLQHNDIL-ELPEFEGN-EALNE 300
Cdd:PLN00113 499 SELMQLKLSENKLSgEIPDELSSCKKLVSLDLSHNQLSgQIPasfSEMPVLSQLD---LSQNQLSgEIPKNLGNvESLVQ 575


                 ....*.
gi 21358045  301 LHASNN 306
Cdd:PLN00113 576 VNISHN 581
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 229-383 3.29e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 66.35  E-value: 3.29e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 229 RLTALLLPYNHIKELPpDLVNMRSLQKIDLMHNDLTSLpEDMGLLRKLDCLYLQHNDILELPEFEGNEALNELHASNNFI 308
Cdd:cd21340   3 RITHLYLNDKNITKID-NLSLCKNLKVLYLYDNKITKI-ENLEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRI 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 309 KII----------------------------PKAMCSNLPHLKILDLRDNKITELpDELCLLRNLNRLDVSNNTIS---V 357
Cdd:cd21340  81 SVVeglenltnleelhienqrlppgekltfdPRSLAALSNSLRVLNISGNNIDSL-EPLAPLRNLEQLDASNNQISdleE 159

                       170       180
                ....*....|....*....|....*.
gi 21358045 358 LPVTLSSLAHLISLQVEGNPIKTIRR 383
Cdd:cd21340 160 LLDLLSSWPSLRELDLTGNPVCKKPK 185
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
139-362 3.97e-12

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 69.34  E-value: 3.97e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  139 TVLTLHDNALVELPPEIGklEKLVRLNVSHNKLSQLPRAMYSlpELRHLNISYNEFVELNPDISDlhMLEFLDGGHNNIQ 218
Cdd:PRK15370 181 TELRLKILGLTTIPACIP--EQITTLILDNNELKSLPENLQG--NIKTLYANSNQLTSIPATLPD--TIQEMELSINRIT 254

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  219 SLPGGIGflVRLTALLLPYNHIKELPPDLVNmrSLQKIDLMHNDLTSLPEDmgLLRKLDCLYLQHNDILELPEfEGNEAL 298
Cdd:PRK15370 255 ELPERLP--SALQSLDLFHNKISCLPENLPE--ELRYLSVYDNSIRTLPAH--LPSGITHLNVQSNSLTALPE-TLPPGL 327

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 21358045  299 NELHASNNFIKIIPKAMCsnlPHLKILDLRDNKITELPDelCLLRNLNRLDVSNNTISVLPVTL 362
Cdd:PRK15370 328 KTLEAGENALTSLPASLP---PELQVLDVSKNQITVLPE--TLPPTITTLDVSRNALTNLPENL 386
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
110-620 5.78e-12

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 68.04  E-value: 5.78e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 110 WNQVPLNNLDLSSNTLTHISPKIENLQSLTVLTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNI 189
Cdd:COG4886  24 LILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDL 103

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 190 SYNEfvelnpDISDLHMLEFLDGGHNNIQSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPED 269
Cdd:COG4886 104 SGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEE 177

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 270 MGLLRKLDCLYLQHNDILELP-EFEGNEALNELHASNNFIKIIPKAMcSNLPHLKILDLRDNKITELPDelcllrnlnrl 348
Cdd:COG4886 178 LGNLTNLKELDLSNNQITDLPePLGNLTNLEELDLSGNQLTDLPEPL-ANLTNLETLDLSNNQLTDLPE----------- 245

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 349 dvsnntisvlpvtLSSLAHLISLqvegnpiktirrdilqcgttrilktlhdravakakeegggvddastsagisvtrlrg 428
Cdd:COG4886 246 -------------LGNLTNLEEL--------------------------------------------------------- 255

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 429 gqmddgdipgnfpdryklrhtrtlavnleeltsvpdqvfqiardegvhvvDFARNQLSTLPNgLQHMKDLvTELVLSNNv 508
Cdd:COG4886 256 --------------------------------------------------DLSNNQLTDLPP-LANLTNL-KTLDLSNN- 282

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 509 igyvpqfisqftrisflnlsnnLLNDLPTEFGVLNTLRELNIANNRFPCIPNCVYELQGLEILIASENHIKMLNVSGLQN 588
Cdd:COG4886 283 ----------------------QLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTL 340

                       490       500       510
                ....*....|....*....|....*....|..
gi 21358045 589 MRRLSTLDLRNNDIETVPPILGNLTNITHLEL 620
Cdd:COG4886 341 ALSLSLLALLTLLLLLNLLSLLLTLLLTLGLL 372
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 112-267 2.53e-11

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 67.18  E-value: 2.53e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  112 QVPLNN-LDLSSNTLT-HISPKIENLQSLTVLTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQ-LPRAMYSLPELRHLN 188
Cdd:PLN00113 426 KLPLVYfLDISNNNLQgRINSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSGaVPRKLGSLSELMQLK 505

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  189 ISYNEFVELNPD-ISDLHMLEFLDGGHNNIQ-SLPGGIGFLVRLTALLLPYNHIK-ELPPDLVNMRSLQKIDLMHNDL-T 264
Cdd:PLN00113 506 LSENKLSGEIPDeLSSCKKLVSLDLSHNQLSgQIPASFSEMPVLSQLDLSQNQLSgEIPKNLGNVESLVQVNISHNHLhG 585


                 ...
gi 21358045  265 SLP 267
Cdd:PLN00113 586 SLP 588
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
498-625 5.90e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 61.87  E-value: 5.90e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 498 LVTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLNDLPTEFGVLNTLRELNIANNRFPCIPNCVYELQGLEILIASENH 577
Cdd:COG4886  68 LLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQ 147

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 21358045 578 IKMLNvSGLQNMRRLSTLDLRNNDIETVPPILGNLTNITHLELVGNPF 625
Cdd:COG4886 148 LTDLP-EPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQI 194
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
261-625 2.63e-09

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 59.56  E-value: 2.63e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 261 NDLTSLPEDMGLLRKLDCLYLQHNDILELPEFEGNEALNELHASNNfikiipkAMCSNLPHLKILDLRDNKITELPDELC 340
Cdd:COG4886  61 LLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPEELA 133

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 341 LLRNLNRLDVSNNTISVLPVTLSSLAHLISLQVEGNPIKTIRRDILQCgttrilktlhdravakakeegggvddastsag 420
Cdd:COG4886 134 NLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNL-------------------------------- 181

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 421 isvtrlrggqmddgdipgnfpdryklrhtrtlaVNLEELtsvpdqvfqiardegvhvvDFARNQLSTLPNGLQHMKDLvT 500
Cdd:COG4886 182 ---------------------------------TNLKEL-------------------DLSNNQITDLPEPLGNLTNL-E 208

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 501 ELVLSNNvigyvpqfisqftrisflnlsnnLLNDLPTEFGVLNTLRELNIANNRFPCIPNcvyelqgleiliasenhikm 580
Cdd:COG4886 209 ELDLSGN-----------------------QLTDLPEPLANLTNLETLDLSNNQLTDLPE-------------------- 245

                       330       340       350       360
                ....*....|....*....|....*....|....*....|....*
gi 21358045 581 lnvsgLQNMRRLSTLDLRNNDIETVPPiLGNLTNITHLELVGNPF 625
Cdd:COG4886 246 -----LGNLTNLEELDLSNNQLTDLPP-LANLTNLKTLDLSNNQL 284
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 115-227 9.06e-09

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 58.71  E-value: 9.06e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  115 LNNLDLSSNTLTHISP-KIENLQSLTVLTLHDNALV-ELPPEIGKLEKLVRLNVSHNKLS-QLPRAMYSLPELRHLNISY 191
Cdd:PLN00113 477 LENLDLSRNQFSGAVPrKLGSLSELMQLKLSENKLSgEIPDELSSCKKLVSLDLSHNQLSgQIPASFSEMPVLSQLDLSQ 556

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 21358045  192 NEFV-ELNPDISDLHMLEFLDGGHNNIQ-SLPGGIGFL 227
Cdd:PLN00113 557 NQLSgEIPKNLGNVESLVQVNISHNHLHgSLPSTGAFL 594
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 125-336 7.76e-08

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 53.25  E-value: 7.76e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 125 LTHIS------PKIENL---QSLTVLTLHDNALVELPPeIGKLEKLVRLNVSHNKLSQLPRaMYSLPELRHLNISYNEFV 195
Cdd:cd21340   4 ITHLYlndkniTKIDNLslcKNLKVLYLYDNKITKIEN-LEFLTNLTHLYLQNNQIEKIEN-LENLVNLKKLYLGGNRIS 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 196 ELNpDISDLHMLEFLdggHNNIQSLPGGIGFLVR---LTALLlpynhikelppdlvnmRSLQKIDLMHNDLTSLpEDMGL 272
Cdd:cd21340  82 VVE-GLENLTNLEEL---HIENQRLPPGEKLTFDprsLAALS----------------NSLRVLNISGNNIDSL-EPLAP 140

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 21358045 273 LRKLDCLYLQHNDILELPEFEGnealnelhasnnfikiipkaMCSNLPHLKILDLRDNKITELP 336
Cdd:cd21340 141 LRNLEQLDASNNQISDLEELLD--------------------LLSSWPSLRELDLTGNPVCKKP 184
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
138-378 2.88e-07

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 53.63  E-value: 2.88e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  138 LTVLTLHDNALVELP---PEIGKLEklvrlnVSHNKLSQLPRAMyslPELRHLNISYNEFVELNPDISDLHMLEFLDGGH 214
Cdd:PRK15387 224 ITTLVIPDNNLTSLPalpPELRTLE------VSGNQLTSLPVLP---PGLLELSIFSNPLTHLPALPSGLCKLWIFGNQL 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  215 NNIQSLPGGI-------GFLVRLTAL------LLPYNHIKELPPDLVNmrSLQKIDLMHNDLTSLPEdmgLLRKLDCLYL 281
Cdd:PRK15387 295 TSLPVLPPGLqelsvsdNQLASLPALpselckLWAYNNQLTSLPTLPS--GLQELSVSDNQLASLPT---LPSELYKLWA 369

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  282 QHNDILELPEFEgnEALNELHASNNFIKIIPKamcsnLP-HLKILDLRDNKITELPdelCLLRNLNRLDVSNNTISVLPV 360
Cdd:PRK15387 370 YNNRLTSLPALP--SGLKELIVSGNRLTSLPV-----LPsELKELMVSGNRLTSLP---MLPSGLLSLSVYRNQLTRLPE 439

                        250
                 ....*....|....*...
gi 21358045  361 TLSSLAHLISLQVEGNPI 378
Cdd:PRK15387 440 SLIHLSSETTVNLEGNPL 457
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
229-496 5.75e-07

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 52.78  E-value: 5.75e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  229 RLTALLLPYNHIKELPPDL-VNMRSLQkidLMHNDLTSLPEDmgLLRKLDCLYLQHNDILELPEFegnealnelhasnnf 307
Cdd:PRK15370 200 QITTLILDNNELKSLPENLqGNIKTLY---ANSNQLTSIPAT--LPDTIQEMELSINRITELPER--------------- 259

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  308 ikiIPKAmcsnlphLKILDLRDNKITELPDelCLLRNLNRLDVSNNTISVLPVTLSSlaHLISLQVEGNPIkTIRRDILQ 387
Cdd:PRK15370 260 ---LPSA-------LQSLDLFHNKISCLPE--NLPEELRYLSVYDNSIRTLPAHLPS--GITHLNVQSNSL-TALPETLP 324

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  388 CGttriLKTLhdravaKAKEEGGGVDDASTSAGISVTRLRGGQMDdgDIPGNFPDRYKlrhtrTLAVNLEELTSVPDQVf 467
Cdd:PRK15370 325 PG----LKTL------EAGENALTSLPASLPPELQVLDVSKNQIT--VLPETLPPTIT-----TLDVSRNALTNLPENL- 386

                        250       260
                 ....*....|....*....|....*....
gi 21358045  468 qiarDEGVHVVDFARNQLSTLPNGLQHMK 496
Cdd:PRK15370 387 ----PAALQIMQASRNNLVRLPESLPHFR 411
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 115-267 6.90e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 50.55  E-value: 6.90e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 115 LNNLDLSSNTLTHIsPKIENLQSLTVLTLHDNALVELPPeIGKLEKLVRLNVSHNKLSQL-------------------- 174
Cdd:cd21340  26 LKVLYLYDNKITKI-ENLEFLTNLTHLYLQNNQIEKIEN-LENLVNLKKLYLGGNRISVVeglenltnleelhienqrlp 103

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 175 --------PRAMYSL-PELRHLNISYNEFVELNPdISDLHMLEFLDGGHNNIQSlpggigflvrltalllpynhIKELPP 245
Cdd:cd21340 104 pgekltfdPRSLAALsNSLRVLNISGNNIDSLEP-LAPLRNLEQLDASNNQISD--------------------LEELLD 162

                       170       180
                ....*....|....*....|..
gi 21358045 246 DLVNMRSLQKIDLMHNDLTSLP 267
Cdd:cd21340 163 LLSSWPSLRELDLTGNPVCKKP 184
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 542-625 7.23e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 50.55  E-value: 7.23e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 542 LNTLRELNIANNRFP-----CI-PNCVYELQG-LEILIASENHIKmlNVSGLQNMRRLSTLDLRNN---DIETVPPILGN 611
Cdd:cd21340  89 LTNLEELHIENQRLPpgeklTFdPRSLAALSNsLRVLNISGNNID--SLEPLAPLRNLEQLDASNNqisDLEELLDLLSS 166

                        90
                ....*....|....
gi 21358045 612 LTNITHLELVGNPF 625
Cdd:cd21340 167 WPSLRELDLTGNPV 180
LRR_8 pfam13855
Leucine rich repeat;
115-171 4.16e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 44.44  E-value: 4.16e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 21358045   115 LNNLDLSSNTLTHISPKI-ENLQSLTVLTLHDNALVELPPE-IGKLEKLVRLNVSHNKL 171
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
274-332 7.43e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 43.67  E-value: 7.43e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 21358045   274 RKLDCLYLQHNDILELPE--FEGNEALNELHASNNFIKIIPKAMCSNLPHLKILDLRDNKI 332
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
160-217 1.96e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.51  E-value: 1.96e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045   160 KLVRLNVSHNKLSQL-PRAMYSLPELRHLNISYNEFVELNPD-ISDLHMLEFLDGGHNNI 217
Cdd:pfam13855   2 NLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
115-481 8.50e-05

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 45.92  E-value: 8.50e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  115 LNNLDLSSNTLTHISPKIENLQSLTVLTLHDNALVELPPeigkleKLVRLNVSHNKLSQLPramySLP-ELRHLNISYNE 193
Cdd:PRK15387 264 LLELSIFSNPLTHLPALPSGLCKLWIFGNQLTSLPVLPP------GLQELSVSDNQLASLP----ALPsELCKLWAYNNQ 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  194 FVELNPDISDLHMLEFLDgghNNIQSLPggigflvrltalllpynhikELPPDLVnmrslqKIDLMHNDLTSLPedmGLL 273
Cdd:PRK15387 334 LTSLPTLPSGLQELSVSD---NQLASLP--------------------TLPSELY------KLWAYNNRLTSLP---ALP 381

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  274 RKLDCLYLQHNDILELPEFEGNeaLNELHASNNFIKIIPKamcsnLPH-LKILDLRDNKITELPDELCLLRNLNRLDVSN 352
Cdd:PRK15387 382 SGLKELIVSGNRLTSLPVLPSE--LKELMVSGNRLTSLPM-----LPSgLLSLSVYRNQLTRLPESLIHLSSETTVNLEG 454

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  353 NTISvlPVTLSSLAHLISLQVEGNPIktIRRDILQCGTTRILKTLH----DRAVAKAKEEGGGVDDASTSagisvtrlrg 428
Cdd:PRK15387 455 NPLS--ERTLQALREITSAPGYSGPI--IRFDMAGASAPRETRALHlaaaDWLVPAREGEPAPADRWHMF---------- 520

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 21358045  429 GQMDDGDIPGNFPDRykLRHTRTLAVNLEELTSVPDQVFQIARDEGVHVVDFA 481
Cdd:PRK15387 521 GQEDNADAFSLFLDR--LSETENFIKDAGFKAQISSWLAQLAEDEALRANTFA 571
LRR_8 pfam13855
Leucine rich repeat;
229-286 1.31e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.20  E-value: 1.31e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045   229 RLTALLLPYNHIKELPPD-LVNMRSLQKIDLMHNDLTSL-PEDMGLLRKLDCLYLQHNDI 286
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGaFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 115-182 2.65e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 44.04  E-value: 2.65e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 21358045  115 LNNLDLSSNTLT-HISPKIENLQSLTVLTLHDNALVELPPE-IGKLEKLVRLNVSHNKLS-QLPRAMYSLP 182
Cdd:PLN03150 444 LQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNGSIPEsLGQLTSLRILNLNGNSLSgRVPAALGGRL 514
LRR_8 pfam13855
Leucine rich repeat;
566-625 2.90e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.43  E-value: 2.90e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 21358045   566 QGLEILIASENHIKMLNVSGLQNMRRLSTLDLRNNDIETVPPI-LGNLTNITHLELVGNPF 625
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGaFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
483-627 3.68e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 43.38  E-value: 3.68e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 483 NQLSTLPNGLQHMKDLVTELVLSNNVIGYVPQFISQFTRISFLNLSNNLLNDLPTEFGVLNTLRELNIANNRFPCIPNCV 562
Cdd:COG4886  13 LLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDL 92

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 21358045 563 YELQGLEILIASENhikmlnvSGLQNMRRLSTLDLRNNDIETVPPILGNLTNITHLELVGNPFRQ 627
Cdd:COG4886  93 GDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTD 150
PLN03150 PLN03150
hypothetical protein; Provisional
 209-284 6.09e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 42.88  E-value: 6.09e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  209 FLDGGHNNIQSL----PGGIGFLVRLTALLLPYNHIK-ELPPDLVNMRSLQKIDLMHNDLT-SLPEDMGLLRKLDCLYLQ 282
Cdd:PLN03150 419 FIDGLGLDNQGLrgfiPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLN 498


                 ..
gi 21358045  283 HN 284
Cdd:PLN03150 499 GN 500
LRR_8 pfam13855
Leucine rich repeat;
182-240 8.81e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.89  E-value: 8.81e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 21358045   182 PELRHLNISYNEFVELNPDI-SDLHMLEFLDGGHNNIQSL-PGGIGFLVRLTALLLPYNHI 240
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
450-650 9.27e-04

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 42.38  E-value: 9.27e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  450 RTLAVNLEELTSVPDQVfqiarDEGVHVVDFARNQLSTLPnglQHMKDLVTELVLSNNVIGYVPQfisqftrisflnlsn 529
Cdd:PRK15370 265 QSLDLFHNKISCLPENL-----PEELRYLSVYDNSIRTLP---AHLPSGITHLNVQSNSLTALPE--------------- 321

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045  530 nllndlptefgvlntlrelniannrfpCIPncvyelQGLEILIASENHIKMLNVS---GLQNmrrlstLDLRNNDI---- 602
Cdd:PRK15370 322 ---------------------------TLP------PGLKTLEAGENALTSLPASlppELQV------LDVSKNQItvlp 362

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 21358045  603 ETVPPILGNLtNITHLELVGNPFRQPRHQILMKGTDAIMSYLRDRIPT 650
Cdd:PRK15370 363 ETLPPTITTL-DVSRNALTNLPENLPAALQIMQASRNNLVRLPESLPH 409
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 159-302 9.42e-04

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 42.55  E-value: 9.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045   159 EKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEFVELNPDISDLHMLEFLD-GGHNNIQSLPGGIGFLVRLTALLLPY 237
Cdd:PLN03210  611 ENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSKNLKEIPDLSMATNLETLKlSDCSSLVELPSSIQYLNKLEDLDMSR 690

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 21358045   238 NHIKELPPDLVNMRSLQKIDLMH-NDLTSLPEdmgLLRKLDCLYLQHNDILELPEFEGNEALNELH 302
Cdd:PLN03210  691 CENLEILPTGINLKSLYRLNLSGcSRLKSFPD---ISTNISWLDLDETAIEEFPSNLRLENLDELI 753
LRR_8 pfam13855
Leucine rich repeat;
320-378 4.52e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.96  E-value: 4.52e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 21358045   320 PHLKILDLRDNKITELPDEL-CLLRNLNRLDVSNNTISVL-PVTLSSLAHLISLQVEGNPI 378
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
115-274 6.39e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 39.53  E-value: 6.39e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 115 LNNLDLSSNTLTHIsPKIENLQSLTVLTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPELRHLNISYNEF 194
Cdd:COG4886 252 LEELDLSNNQLTDL-PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLL 330

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 195 VELNPDISDLHMLEFLDGGHNNIQSLPGGIGFLVRLTALLLPYNHIKELPPDLVNMRSLQKIDLMHNDLTSLPEDMGLLR 274
Cdd:COG4886 331 KGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDA 410
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 68-327 7.93e-03

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 39.47  E-value: 7.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045    68 TLNLSNKALARVPKRLYDINeadadskAVNLEQLTIKEEDAWWNQVPLNNLdlssntLTHISPkienlqSLTVLTLHDN- 146
Cdd:PLN03210  729 WLDLDETAIEEFPSNLRLEN-------LDELILCEMKSEKLWERVQPLTPL------MTMLSP------SLTRLFLSDIp 789

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045   147 ALVELPPEIGKLEKLVRLNVSHNK-LSQLPRAMySLPELRHLNISYNEFVELNPDISdlhmlefldgghNNIQSlpggig 225
Cdd:PLN03210  790 SLVELPSSIQNLHKLEHLEIENCInLETLPTGI-NLESLESLDLSGCSRLRTFPDIS------------TNISD------ 850

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045   226 flvrltaLLLPYNHIKELPPDLVNMRSLQKIDLMH-NDLTSLPEDMGLLRKLDclYLQHNDILELPEFEGNEALNEL-HA 303
Cdd:PLN03210  851 -------LNLSRTGIEEVPWWIEKFSNLSFLDMNGcNNLQRVSLNISKLKHLE--TVDFSDCGALTEASWNGSPSEVaMA 921

                         250       260
                  ....*....|....*....|....
gi 21358045   304 SNNFIKIIPKAMCSNLPHLKILDL 327
Cdd:PLN03210  922 TDNIHSKLPSTVCINFINCFNLDQ 945
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 112-334 9.16e-03

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 38.49  E-value: 9.16e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 112 QVPLNNLDLSSNTLTHISPKIENLQSLTV--LTLHDNALVELPPEIGKLEKLVRLNVSHNKLSQLPRAMYSLPE------ 183
Cdd:cd00116   2 QLSLKGELLKTERATELLPKLLCLQVLRLegNTLGEEAAKALASALRPQPSLKELCLSLNETGRIPRGLQSLLQgltkgc 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21358045 184 -LRHLNISYNEFVELNPD-ISDLHMLEFLDGGHNNIQSLPGGIGFLVrLTALllpynhiKELPPDLvnmrslQKIDLMHN 261
Cdd:cd00116  82 gLQELDLSDNALGPDGCGvLESLLRSSSLQELKLNNNGLGDRGLRLL-AKGL-------KDLPPAL------EKLVLGRN 147

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 21358045 262 DLTS-----LPEDMGLLRKLDCLYLQHNDILElpefEGNEALNELHASNnfikiipkamcsnlPHLKILDLRDNKITE 334
Cdd:cd00116 148 RLEGasceaLAKALRANRDLKELNLANNGIGD----AGIRALAEGLKAN--------------CNLEVLDLNNNGLTD 207
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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